intimal hyperplasia post carotid...
TRANSCRIPT
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Intimal Hyperplasia Post Carotid Endarterectomy
George H. Meier, MD RVT FACSProfessor and Chief, VascularUniversity of Cincinnati COM
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Disclosures
None
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Anyone who says they understand Intimal
Hyperplasia, is lying….
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Associations with IH• Embolectomy catheter induced,
associated with endothelial denudation
• Common after endarterectomy in any location
• Common after balloon angioplasty (~30%)
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Am J Surgery 1967
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mTOR Pathway
• Target for sirolimus
• Dysregulation associated with intimal hyperplasia
• Complicated!
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E2F
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E2F in LEB
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Conclusions• Carotid restenosis, although not
uncommon, rarely leads to stroke
• Treating asymptomatic restenosis is unwarranted
• We need to know more….
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