inheco on deck thermal cycler - odtc implementation of ... · thermal innovations & products 3...

Thermal Innovations & Products 1

INHECO On Deck Thermal Cycler - ODTC®

Implementation of SiLA communication interface on

embedded mini PC

SiLA conference Sept. 22, 2014, Basel

Dr. Volker Lob

INHECO GmbH, 82152 Martinsried, Germany, [email protected]

mailto:[email protected]


• Company

• ODTC®: On Deck Thermal

Cycler; Product Details

• Hardware concept and

SiLA integration level

• Challenges and Problems

• Perspective

Content


2000 INHECO founded by Guenter

Tenzler

2001 Focus on thermal products in lab

automation

2003 First PCR developments

2005 First IVD product development

2006 ISO 9001:2000 certified

2009 First IVD Project in the US

successfully completed, move to

new premises

2014 +50 employees

Company - History

INHECO develops, manufactures and Distributes products

for thermo-mechanical applications.


ODTC®: Designed for LabAutomation

Thermocycling

Heating

Cooling

Sealing

VCM® Technology

SiLA enables “plug and play” integration and guarantees cost- and time-

effective development of complex lab-platforms for high throughput

applications.


Compact and Innovative Design for Optimal Deck Integration

• Very low height to avoid

interference with gripper

or pipettor movement

• Competitor products are

too large for proper on-

deck integration

• Power supply and

controller are located in a

separate box underneath

the deck

ODTC typical competitor product

P&CU

Liquid handling platform


Unique Thermal Performance with VCM®-Technology

• Almost ZERO well-to-well

temperature uniformity

• Almost ZERO delay-time during

PCR-Cycle

• Excellent well-to-well temperature

uniformity even with non-

homogeneous sample loading

• Still very good temperature

uniformity when lid is open


Various Options for Plate Sealing

• Robot manageable sealing mats, pick-and-

place with gripper

• Presealed disposables (e.g. sealing foils)

• Sealing mat mounted in the lid, may be used

with presealed and unsealed disposables

(cross contamination issues must be

considered according to assay type)

sealing mat robot

manageable

sealing mat sealing foil


Free programmable temperature curves

• Easy programming of thermo cycles

• Input of process parameters:

o plate type

o filling level

o target temperature curve

ramp speed,

plateau temperature

plateau time

• Free programmable temperature

curves from +4°C to +99°C

• Lid can be opened and closed

during operation – pipetting during

thermocycle runs is possible

INHECO Skript Editor

Thermal Innovations & Products

9

low-level serial

communication

(RS232)

SiLA

(TCP/IP)

Benefits:

• High integration level

• Size of a matchbox

• Standard communication Interface (SiLA <–> RS232)

• Encapsulated system (modular system architecture)

• I/O Port for further device controlling/signaling

Encapsulated hardware Module for SiLA communication

INHECO SiLA Module: Interfaces


10

Internal serial real-time interface (2 Layer)

ODTC® internal serial communikation (RS232)

This SiLA interface module makes integration into lab automation

systems very easy. Platform manufacturers and Third-Party-

Integrators can expand their product line functionality with minimal

configuration time and effort.


ODTC® supports SiLA integration level 3

• Software (driver) with SiLA-Library on the

device

• Easy replacement of devices

• No additional hardware required

• Standard wiring to the PMS (Ethernet)

ODTC®


ODTC® SiLA Commands

SiLA Command Mandatory Required Optional SpecificAbort ×

DoContinue ×

GetDeviceIdentification ×

GetStatus ×

Initialize ×

LockDevice ×

Pause ×

Reset ×

UnlockDevice ×

GetParameters ×

PrepareForInput ×

PrepareForOutput ×

SetParameters ×

ExecuteMethod ×

GetConfiguration ×

SetConfiguration ×

CloseDoor ×

OpenDoor ×

ReadActualTemperature ×

StopMethod ×

SiLA Device Class 30 (PCR Cycler, version: 1.2.01)

Commands:

- 9 Mandatory Commands

- 4 Required Commands

- 3 Optional Commands

- 4 Specific Commands


13

Challenges and Problems

Successful Validation

1. Fraunhofer LACS (PMS)

2. Infoteam Library (Driver)

Challenges

• No SOAP Server within the .NET Compact Framework 3.5 (MS Visual Studio )

• Translation between managed (C#) and unmanaged Code (C++) -> Middleware

• Limited resources (embedded PC), space saving and runtime optimized

programming.

• Architecture encapsulate device-specific properties (device.dll)

Problems

• “Specific commands” dilute the standard

• Interpretation of the specification (e.g. RequestID unique during lifetime)


14

• SiLA certification for the INHECO SiLA Module

• Equip further INHECO Products with the SiLA -> e.g. new On Deck

Incubator Line (Scila)

Perspective

SiLA


15

ODTC® to be exhibited at MipTec 2014

• SiLA Live Integration Demo, booth # A 41/42

• Hamilton Robotics, booth # C 53

For further product Information please

contact:

INHECO GmbH

Frauenhoferstrasse 11

82152 Martinsried

Germany

Tel.: +49 89 899593 – 101

[email protected]

www.inheco.com

Contact

mailto:[email protected]

http://www.inheco.com/

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