infection. pathogenicity and virulence of microorganisms. types of infection. vinnitsa national...
DESCRIPTION
The main properties of pathogen 1. Pathogenicity 2. Infectivity 3. Communicability 4. Adhesiveness 5. Invasiveness 6. Toxigenicity 1.TRANSCRIPT
![Page 1: Infection. Pathogenicity and virulence of microorganisms. Types of infection. Vinnitsa National Pirogov Memorial Medical University / Department of microbiology](https://reader036.vdocuments.us/reader036/viewer/2022062413/5a4d1b4c7f8b9ab0599a5f8d/html5/thumbnails/1.jpg)
Infection. Pathogenicity and virulence of microorganisms.
Types of infection.
Vinnitsa National Pirogov Memorial Medical University / Department of microbiology
![Page 2: Infection. Pathogenicity and virulence of microorganisms. Types of infection. Vinnitsa National Pirogov Memorial Medical University / Department of microbiology](https://reader036.vdocuments.us/reader036/viewer/2022062413/5a4d1b4c7f8b9ab0599a5f8d/html5/thumbnails/2.jpg)
Infection is the active penetration of pathogenic microorganism into the host organism. In result of penetration infectious process is developed.
![Page 3: Infection. Pathogenicity and virulence of microorganisms. Types of infection. Vinnitsa National Pirogov Memorial Medical University / Department of microbiology](https://reader036.vdocuments.us/reader036/viewer/2022062413/5a4d1b4c7f8b9ab0599a5f8d/html5/thumbnails/3.jpg)
The main properties of pathogen
1. Pathogenicity2. Infectivity3. Communicability4. Adhesiveness5. Invasiveness6. Toxigenicity
1.
![Page 4: Infection. Pathogenicity and virulence of microorganisms. Types of infection. Vinnitsa National Pirogov Memorial Medical University / Department of microbiology](https://reader036.vdocuments.us/reader036/viewer/2022062413/5a4d1b4c7f8b9ab0599a5f8d/html5/thumbnails/4.jpg)
Adherence factorsAdhesins of the microorganisms:
1. Fimbriae and adhesive pili2. Capsule3. Peptidoglycane4. Teichoic and lipoteichoic acids5. Fatty acids6. A-protein (S.aureus) and M-protein
(S.pyogenes) 7. Ligands
![Page 5: Infection. Pathogenicity and virulence of microorganisms. Types of infection. Vinnitsa National Pirogov Memorial Medical University / Department of microbiology](https://reader036.vdocuments.us/reader036/viewer/2022062413/5a4d1b4c7f8b9ab0599a5f8d/html5/thumbnails/5.jpg)
![Page 6: Infection. Pathogenicity and virulence of microorganisms. Types of infection. Vinnitsa National Pirogov Memorial Medical University / Department of microbiology](https://reader036.vdocuments.us/reader036/viewer/2022062413/5a4d1b4c7f8b9ab0599a5f8d/html5/thumbnails/6.jpg)
Pathogenicity factors: Invasion factors
1. Hyaluronidase2. Lecithinase3. Deoxyribonuclease and ribonuclease4. Fibrinolysine5. Plasmocoagulase6. Collagenase7. Hemolysins8. Elastase9. IgA protease10. Leukocidins
![Page 7: Infection. Pathogenicity and virulence of microorganisms. Types of infection. Vinnitsa National Pirogov Memorial Medical University / Department of microbiology](https://reader036.vdocuments.us/reader036/viewer/2022062413/5a4d1b4c7f8b9ab0599a5f8d/html5/thumbnails/7.jpg)
![Page 8: Infection. Pathogenicity and virulence of microorganisms. Types of infection. Vinnitsa National Pirogov Memorial Medical University / Department of microbiology](https://reader036.vdocuments.us/reader036/viewer/2022062413/5a4d1b4c7f8b9ab0599a5f8d/html5/thumbnails/8.jpg)
Pathogenicity factors:ToxinsToxin is a specific substance, often a metabolic product of
microorganism, that damages the host.Classification: 1. Endotoxin2. Exotoxin
![Page 9: Infection. Pathogenicity and virulence of microorganisms. Types of infection. Vinnitsa National Pirogov Memorial Medical University / Department of microbiology](https://reader036.vdocuments.us/reader036/viewer/2022062413/5a4d1b4c7f8b9ab0599a5f8d/html5/thumbnails/9.jpg)
Classification of exotoxinsCytotoxins (enterotoxins and
dermatonecrotoxins)Neurotoxins Membranotoxins Miscellaneous group
![Page 10: Infection. Pathogenicity and virulence of microorganisms. Types of infection. Vinnitsa National Pirogov Memorial Medical University / Department of microbiology](https://reader036.vdocuments.us/reader036/viewer/2022062413/5a4d1b4c7f8b9ab0599a5f8d/html5/thumbnails/10.jpg)
Infectious process
Infectious process is a complex of physiological, adaptive and pathological changes that arise in the host organism due to infection
![Page 11: Infection. Pathogenicity and virulence of microorganisms. Types of infection. Vinnitsa National Pirogov Memorial Medical University / Department of microbiology](https://reader036.vdocuments.us/reader036/viewer/2022062413/5a4d1b4c7f8b9ab0599a5f8d/html5/thumbnails/11.jpg)
Infectious disease
Infectious disease is any change from a state of health in which part or all of the host body is not able of carrying on its normal functions due to presence of a parasite or its products
![Page 12: Infection. Pathogenicity and virulence of microorganisms. Types of infection. Vinnitsa National Pirogov Memorial Medical University / Department of microbiology](https://reader036.vdocuments.us/reader036/viewer/2022062413/5a4d1b4c7f8b9ab0599a5f8d/html5/thumbnails/12.jpg)
Phases of infectious disease
1. Incubation period2. Prodromal period3. The period of illness4. Outcome of disease
![Page 13: Infection. Pathogenicity and virulence of microorganisms. Types of infection. Vinnitsa National Pirogov Memorial Medical University / Department of microbiology](https://reader036.vdocuments.us/reader036/viewer/2022062413/5a4d1b4c7f8b9ab0599a5f8d/html5/thumbnails/13.jpg)
Outcome of infectious disease The outcome of infectious disease may be:1. The recovery2. The formation of convalescent carrying3. The persistence of pathogen in the host4. The death
![Page 14: Infection. Pathogenicity and virulence of microorganisms. Types of infection. Vinnitsa National Pirogov Memorial Medical University / Department of microbiology](https://reader036.vdocuments.us/reader036/viewer/2022062413/5a4d1b4c7f8b9ab0599a5f8d/html5/thumbnails/14.jpg)
Mechanisms and types of infection transmission
The main types of infection transmission are by: Inhalation (air-borne transmission)
![Page 15: Infection. Pathogenicity and virulence of microorganisms. Types of infection. Vinnitsa National Pirogov Memorial Medical University / Department of microbiology](https://reader036.vdocuments.us/reader036/viewer/2022062413/5a4d1b4c7f8b9ab0599a5f8d/html5/thumbnails/15.jpg)
Mechanisms and types of infection transmission
Ingestion (waterborne, food borne, and hand borne transmission) and poor sanitation
![Page 16: Infection. Pathogenicity and virulence of microorganisms. Types of infection. Vinnitsa National Pirogov Memorial Medical University / Department of microbiology](https://reader036.vdocuments.us/reader036/viewer/2022062413/5a4d1b4c7f8b9ab0599a5f8d/html5/thumbnails/16.jpg)
Mechanisms and types of infection transmission
Inoculation
![Page 17: Infection. Pathogenicity and virulence of microorganisms. Types of infection. Vinnitsa National Pirogov Memorial Medical University / Department of microbiology](https://reader036.vdocuments.us/reader036/viewer/2022062413/5a4d1b4c7f8b9ab0599a5f8d/html5/thumbnails/17.jpg)
Mechanisms and types of infection transmission
Contact (contact transmission)
Direct contact Indirect contact Sexual intercourse
![Page 18: Infection. Pathogenicity and virulence of microorganisms. Types of infection. Vinnitsa National Pirogov Memorial Medical University / Department of microbiology](https://reader036.vdocuments.us/reader036/viewer/2022062413/5a4d1b4c7f8b9ab0599a5f8d/html5/thumbnails/18.jpg)
Mechanisms and types of infection transmission
Biting of blood sucking insects (vector borne transmission)
![Page 19: Infection. Pathogenicity and virulence of microorganisms. Types of infection. Vinnitsa National Pirogov Memorial Medical University / Department of microbiology](https://reader036.vdocuments.us/reader036/viewer/2022062413/5a4d1b4c7f8b9ab0599a5f8d/html5/thumbnails/19.jpg)
Mechanisms and types of infection transmission
Person-to-person through the placenta (congenital transmission)
![Page 20: Infection. Pathogenicity and virulence of microorganisms. Types of infection. Vinnitsa National Pirogov Memorial Medical University / Department of microbiology](https://reader036.vdocuments.us/reader036/viewer/2022062413/5a4d1b4c7f8b9ab0599a5f8d/html5/thumbnails/20.jpg)
Classification of the infectionsManifested infectionAtypical infection Inapparent infection
Endogenous infection (autoinfection) Exogenous infection
Acute infection (till 3 months) Chronic infection (after 6 months) Persistent infection (years)
![Page 21: Infection. Pathogenicity and virulence of microorganisms. Types of infection. Vinnitsa National Pirogov Memorial Medical University / Department of microbiology](https://reader036.vdocuments.us/reader036/viewer/2022062413/5a4d1b4c7f8b9ab0599a5f8d/html5/thumbnails/21.jpg)
Classification of the infections Primary infection Secondary infection
Mixed infection Reinfection Super infection
Pandemic Epidemic Endemic Sporadic