ICP Mass Spectrometers

with DRC technology

by Keith Hutchison

ICP Mass Spectrometers

with DRC technology

by Keith Hutchison

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Flame + THGA Zeeman

Flame + HGA Furnace

Dedicated THGA Zeeman Furnace (no flame)

Flame (opt. HGA Furnace)

Flame (opt. HGA Furnace)

High-end Flame/

Furnace

Entry-level Flame

(Furnace)

Price

Fea

ture

s/P

erfo

rman

ce

ELAN 9000

ELAN DRC-e

ELAN DRC II

FIMS

AAnalyst 200

AAnalyst 400

AAnalyst 600

AAnalyst 700

AAnalyst 800

Optima 2100DV

Optima 5100DV

Optima 5200DV

Optima 5300V

Conventional ICP-MS system

DRC Technology Systems

Robust basic system

Robust HF resistant sample intro DRC system

Lowest BEC, Highest S/B

Hybrid system

Simultaneous Systems

Lower Cost system

Dual view, single detector

Dual view, single detector + extended λ

Vertical torch/Radial View, dual detector

Dual view, dual detector Optima 5300DV

AA

ICP

-OE

SIC

P-

MS

Dedicated Hg CVAA)

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ELAN Product History

ELAN 250 1983ELAN 500 1987ELAN 5000 1990ELAN 6000 1994ELAN 6100 & DRC 1999ELAN DRC Plus 2001ELAN 9000 & DRCII 2002DRC-e 2003Design Enhancements 200521CFR Part 11 s/w 2005Chromera speciation s/w 2005ELAN 3.4 software 2007

ICP-MS 25 Years Mature

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ELAN Product Line

ELAN 9000• Rugged and

reliable• Designed for

routine, high throughput labs

• Proven methodology for environmental, clinical and geochemical applications

ELAN DRCII

• Targeted at ultra-trace analyses

• Ideal for research-oriented applications

• Exciting potential for other application areas

ELAN DRCELAN DRC --ee

��Targeted at trace Targeted at trace analysisanalysis

��Designed for routine, Designed for routine, high throughput labshigh throughput labs

��Potential for lower Potential for lower detection limits and detection limits and reduced interferencesreduced interferences

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Schematic Diagram of ICP-MS: ELAN 9000

Detector

ShadowStop

Turbomolecularpumps

Roughing pumps

Ar gas in

Main Q-poleDC + AC ( U + Vcosωωωωt )

E-LensPre-filterAC only ( V cosωωωωt )

+++

++++

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A little review…

The quadrupole is a mass filter!It’s a sequential scanning device,

ramping through the periodic table from low to high mass in about 1/100th second.

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Common ICP-MS Spectral Interferences

POLYATOMIC SPECIES

INTERFERED ANALYTE

12C15N, 12C14NH 27Al38Ar1H 39K40Ar 40Ca35Cl16O 51V35Cl16O1H 52Cr36Ar16O 52Cr40Ar12C 52Cr38Ar16O1H 55Mn40Ar16O 56Fe40Ar16O1H 57Fe40Ar35Cl 75AsArAr 80Se

What is produced in an argon plasma?What is produced in an argon plasma?

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Schematic Diagram of ICP-MS: ELAN 9000

Detector

ShadowStop

Turbomolecularpumps

Roughing pumps

Ar gas in

Main Q-poleDC + AC ( U + Vcosωωωωt )

E-LensPre-filterAC only ( V cosωωωωt )

+++

++++

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Schematic Diagram of ELAN DRCReaction

gas in

Detector

Autolens

Shadow stop

DRC

Turbo pump

Roughing pump

Q-pole mass filter

Pre-filter

Ar gas in

++

++

+++

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100

ppt S

tand

ard

in W

ater

with

out

Rea

ctio

n G

as

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100

ppt S

tand

ard

in W

ater

Usi

ng

Rea

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n G

as

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Robust Ion Lens System of ELAN DRC

Neutral species from plasma

DRC cell ( U + V cos ωωωωt )±±±± 150 v

ShadowStopGrounded

AutoLens

M+

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DR

C R

ods

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Snap in lens mount

Shadow stop sits on posts. Two fingers to remove a nd replace Shadow stop sits on posts. Two fingers to remove a nd replace lens mount. Retrolens mount. Retro --fit able onto existing instruments.fit able onto existing instruments.

Snap out and Snap inSnap out and Snap in

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What’s New in ELAN v3.4 Software:DRC MD: A New DRC Method

Development Tool

• Simultaneous two-parameter optimization• The ELAN software automatically runs the required s olutions and

selects the best cell conditions

~ DRC Method Development has never been easier!• Outputs results to automatically create a quantitat ive method• Allows you to reprocess previous results with modif ied criteria

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High Throughput Sample Analysis with the SC-FAST and ELAN ICP-MS

High Throughput Sample Analysis with the SC-FAST and ELAN ICP-MS

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What is FAST?

• A Complete Sample Introduction System~ Autosampler~ Switching valve~ On-Line addition of internal standards~ PFA-ST nebulizer~ Peltier-cooled spray chamber

• Direct Nebulization Using Flow Injection~ Filled sample loop takes the role

of the sample vial~ Solution nebulized continuously

as the sample loop empties

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Benefits of the SC-FAST

• High Throughput~ Reduce uptake, stabilization, and rinsing time~ High speed vacuum loading of sample~ Eliminate sample contact with peristaltic pump tubing~ Probe is rinsed while sample is being analyzed

• Constant Sample Flow Rate

• Stable QC

• Integrated with ELAN Software

SC-FAST saves argon, electricity, and reduces consu mables costs.

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Steps in an ICP-MS Analysis

• Autosampler Movement

• Sample Uptake Time

• Plasma Stabilization Time

• Measurement Time

• Rinse Time

Events in Blue are Significantly Shortened

with the SC-FAST

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Normal ICP-MS Sample Introduction

-12 to -48 RPM

Sample passes through peristaltic pump tubing.

On-Line Addition of Internal Standard

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SC-FAST ICP-MS Sample Introduction

-8 RPM

On-Line Addition of Internal Standard

No contact between sample and peristaltic pump tubing.

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SC

-FA

ST

Flo

w D

iagr

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USEPA Methods Included

• Turnkey USEPA Methods included

~ 200.8

~ 6020• Prepared specifically for the ELAN

• Time tested for over ten years

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