icawc 2014 - canine parvovirus - cagri akkin
DESCRIPTION
ICAWC 2014 Istanbul - Cagri Akkin's presentation on Canine Parvovirus covers diagnosis, treatment, protection and vaccination.TRANSCRIPT
CONTENTSCANINE PARVOVIRAL ENTERITIS
VomitingDiarrheaSevere dehydration Endotoxic or septic shock Multiple organ failureWithout treatment
WHICH BREEDS ARE UNDER RISKETIOLOGY HOW CPV INFECTS A DOGPATHOPHYSIOLOGYCLINICAL FINDINGSDIAGNOSIS TREATMENT Fluid Therapy
Systemic AntibioticsAnti-EmeticsAggressive Adjunctive TreatmentsEradication of Intestinal Parasites
PREVENTION AND CONTROL
WHAT IS CPV?CANINE PARVOVIRAL ENTERITIS
Vomiting
WHAT IS CPV?CANINE PARVOVIRAL ENTERITIS
Diarrhea
WHAT IS CPV?CANINE PARVOVIRAL ENTERITIS
Severe dehydration
WHAT IS CPV?CANINE PARVOVIRAL ENTERITIS
Endotoxic or septic shock
WHAT IS CPV?CANINE PARVOVIRAL ENTERITIS
Multiple organ failure
WHAT IS CPV?CANINE PARVOVIRAL ENTERITIS
Without treatment
Which breeds are under risk
Etiology DNA1970
CPV-2b
HOW CPV INFECTS A DOG
HOW CPV INFECTS A DOG
HOW CPV INFECTS A DOG
Pathophysiology
Pathophysiology
Infection in utero or in pups <8wk old or born to unvaccinated dams
4–5 days later
Clinical Findings
Physical examination findings can include depression, fever, dehydration, and intestinal loops that are dilated
and fluid filled. Abdominal pain warrants further investigation to rule out the potential complication of
intussusception. Severely affected animals may present collapsed with prolonged capillary refill time, poor pulse quality, tachycardia, and hypothermia—signs potentially consistent with septic shock. Although CPV-associated leukoencephalomalacia has been reported, CNS signs
are more commonly attributable to hypoglycemia, sepsis, or acid-base and electrolyte abnormalities. Inapparent or
subclinical infection is common.
Diagnosis
Clinical signs Leukopenia, lymphopenia
ELISA PCR Rapid test kits
Treatment
Fluid Therapy
Treatment
Systemic Antibiotics
Treatment
Anti-Emetics
TreatmentAggressive Adjunctive Treatments
A polyvalent equine origin antiserum against LPS endotoxin
Antiserum
Convalescent serum Recombinant granulocyte colony stimulating factor (rG-
CSF)
Oseltamivir
Treatment
Eradication of Intestinal Parasites
Treatment
Nutrition
PPN
A liquid diet
Prevention and Control
Vaccination for puppies
6–8, 10–12, and 14–16 wk
Prevention and Control
Vaccination for adults
Once a year
Prevention and Control
Isolation housing
Gowning and gloving of personnel
Frequent and thorough cleaning
Prevention and Control
1:30
BIBLIOGRAPHY
Openi.nlm.nih.gov
Histology-world.com
dvm360.com
The Merck Veterinary Manual 8th edition
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