histology various type of epithelium

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Simple Squamous Epithelium Composed of a single layer of flattened cells lying on a basement membrane. In section only their flattened nuclei are often visible. Function: Provides a selective barrier which allows for filtration, passive diffusion and pinocytosis.

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Page 1: Histology   various type of epithelium

Simple Squamous Epithelium

Composed of a single layer of flattened cells lying on a

basement membrane. In section only their flattened nuclei are

often visible. Function: Provides a selective barrier which

allows for filtration, passive diffusion and pinocytosis.

Page 2: Histology   various type of epithelium

A single layer of cuboidal cells with rounded nuclei, lying on a

basement membrane. They are often found lining ducts and may possess

basal infoldings. Function: They transport fluids and may modify the

contents of the lumen by selective absorption.

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Function:

Absorption, lubrication or movement of luminal contents.

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Uterian tube

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Pseudostratified Epith. Treachea

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Pseudostratified Epididymis

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Stratified columnar/cuboidal epith

Multiple layers of cells in which the surface layer is cuboidal or

columnar.

Function: Protection or secretion.

Location examples: Male Urethra, Large Glanduclar Ducts, Sweat

Glands

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Transitional

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Simple Cuboidal Epith

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Simple Cuboidal Salivary gland

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Fig. 20.7

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to protect

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where diffusion is important

where tissues are

involved in secretion

and absorption: larger

cells because of the

machinery of

production, packaging,

and energy

requirements

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“ciliated” literally = eyelashes

(see next page)

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Stratified: regenerate from below

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Rare…

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Rare…

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Endothelium

A simple squamous

epithelium that lines the

interior of the

circulatory vessels and

heart

Mesothelium

Simple squamous epithelium that lines the

peritoneal, pleural and pericardial cavities and covers

the viscera

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Glands

• Epithelial cells form them

• Production & secretion of needed substances

• Are aqueous (water-based) products

• The protein product is made in rough ER, packed into secretory granules by Golgi apparatus, released from the cell by exocytosis

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Classification of glands

• By where they release their product

– Exocrine: external secretion onto body surfaces

(skin) or into body cavities

– Endocrine: secrete messenger molecules

(hormones) which are carried by blood to target

organs; “ductless” glands

• By whether they are unicellular or

multicellular

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Exocrine glandsunicellular or multicellular

Unicellular: goblet cell scattered within epithelial lining

of intestines and

respiratory tubes

Product: mucin

mucus is mucin & water

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Multicellular exocrine glands

Epithelium-walled

duct and a

secretory unit

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• Cilia

– Whiplike motile extentions of the apical surface membranes

• Flagellum

– Long isolated cilium

– Only found as sperm in human

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Classes of Connective Tissue: note the cell types

and great variety of subclasses

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*

Classes of Connective Tissue

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*

Classes of Connective Tissue

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Classes of Connective Tissue

*

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Page 47: Histology   various type of epithelium

Classes of Connective Tissue

*

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Membranes that combine epithelial sheets

plus underlying connective tissue proper (see

next slide)

• Cutaneous membranes– Skin: epidermis and dermis

• Mucous membranes, or mucosa– Lines every hollow internal organ that opens to the outside

of the body

• Serous membranes, or serosa– Slippery membranes lining the pleural, pericardial and

peritoneal cavities

– The fluid formed on the surfaces is called a transudate

• Synovial membranes– Line joints

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(a)Cutaneous membrane

(b)Mucous membrane

(c)Serous membrane

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• Four basic types of tissue

– Epithelium

– Connective tissue

– Muscle tissue

• Skeletal

• Cardiac

• Smooth

– Nervous tissue

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• Four basic types of tissue

– Epithelium

– Connective tissue

– Muscle tissue

– Nervous tissue

• Neurons

• Supporting cells

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Page 57: Histology   various type of epithelium

Tissue response to injury

• Immune: takes longer and is highly specific

• Inflammation

– Nonspecific, local, rapid

– Inflammatory chemicals

– Signs: heat, swelling, redness, pain

• Repair – two ways

– Regeneration

– Fibrosis and scarring

• Severe injuries

• Cardiac and nervous tissue

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Page 59: Histology   various type of epithelium

Tumors (neoplasms): abnormal growth of

cells

• Adenoma – neoplasm of glandular epithelium,

benign or malignant

• Carcinoma – cancer arising in an epithelium

(90% of all human cancers)

• Sarcoma – cancer arising in mesenchyme-

derived tissue (connective tissues and muscle)

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STEM CELLS….

STEM CELLS

______Inner cell mass becomes the baby