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Contents

Welcome Letter ....................................................................................................................................................... 3

Introduction ............................................................................................................................................................. 4

About I-BFM SG .................................................................................................................................................... 4

Aims and Objectives ............................................................................................................................................. 4

Past Annual Meetings ........................................................................................................................................... 5

About Childhood Leukemia and Lymphoma Symposium (CLLS) ......................................................................... 5

Organisation ............................................................................................................................................................. 5

Venue ....................................................................................................................................................................... 7

About Helsinki ....................................................................................................................................................... 7

Important Deadlines Overview ................................................................................................................................ 8

Partnership Categories ............................................................................................................................................. 9

Individual Sponsorship Options.............................................................................................................................. 10

Special Sponsorship Options for Childhood Leukemia and Lymphoma Symposium (CLLS) ................................... 13

Exhibition ............................................................................................................................................................... 13

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Welcome Letter

Dear colleagues and friends,

It is a great pleasure and honor to welcome you to Finland.

On behalf of the Nordic Society of Hematology and Oncology (NOPHO) and the local organizers, we warmly invite you to the 29th Annual Meeting of the International BFM Study Group (May 19-20, 2018) and the 11th Biennial Childhood Leukemia and Lymphoma Symposium (May 21-22, 2018) which will be held in Helsinki.

It is a privilege for NOPHO and the local organizers to host these meetings first time in the Nordic countries. NOPHO has been an official member the I-BFM SG since 2007, and Nordic clinicians, researchers and patients have benefited from this fruitful international collaboration enormously.

The meetings will be attended by major current and future opinion leaders in the field of pediatric hematological malignancies. It will provide excellent opportunities for clinicians and researchers from all countries in Europe and other parts of the world to meet, present data and plan future research in a friendly stimulating atmosphere.

Helsinki is the most popular international congress city in the Nordic countries with excellent flight connections and facilities.

With its seaside location and rich cultural scene, Helsinki offers memorable experiences in addition to the congress itself.

We are looking forward to seeing you in Helsinki, to continue the valuable and enjoyable I-BFM tradition.

With warmest regards

Jukka Kanerva, local chair

On behalf of NOPHO and the local organizing committee

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Introduction About I-BFM SG Leukemias and lymphomas represent around fifty percent of malignancies occurring in children and adolescents. Studies in leukemias - particularly acute lymphoblastic leukemia - in these age groups have been a model for clinical and basic research beyond pediatric hemato-oncology since decades. As a result of sustained and well-organized research largely based on cooperative group efforts since the early 1960s, childhood and adolescent leukemias and lymphomas can now be successfully treated in almost 80% of patients. In the most common type of leukemia – acute lymphoblastic leukemia - cure rates with modern treatment protocols meanwhile exceed 80%. Despite this overall success, there are still subgroups of leukemia with a dismal prognosis.

The International BFM Study Group (I-BFM SG) is dedicated to promoting both research and clinical care for children and adolescents with leukemia and lymphoma. A growing number of participating national study groups from meanwhile more than 30 countries world-wide collaborates in committees and associated working groups addressing important aspects of clinical and basic research in the field of leukemia and lymphoma occurring during childhood and adolescence. The results are shared and discussed in meetings on a regular basis, guaranteeing fast and systematic transition of research findings to clinical care.

Aims and Objectives The tremendous success in the therapy of acute lymphoblastic leukemia in children and adolescents is owed to well organized long-term research efforts, making use of large populations of patients. No less important is an effective combination with biological research and exchange of information. To approach the remaining questions, collaborative efforts are even more indicated. Uniform approaches in research and clinical trials ensure large enough data sets, reproducibility of data and expertise in demanding techniques. The I-BFM Study Group hopes to continue the success story by organizing joined proceedings. Objectives of the I-BFM Study Group are

• To foster the information exchange among the participating groups, including preliminary results. • To promote research projects in childhood leukemias and related disorders, including non-Hodgkin's

lymphomas. • To promote prospective randomized clinical trials, using consensus approaches and allowing the

participation of other groups. • To activate cooperative projects for biological research. • To promote translation of findings from basic to clinical research and vice versa. • To study rare problems.

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Past Annual Meetings 1987 - DE-Münster (Schellong) 1999 - IT-Monza (Masera) 2009 - IT-Bergamo (Biondi, Masera) 1988 - NL-Eindhofen (Kamps) 2000 - NL-Groningen (Kamps) 2010 - TR-Antalya (Yüksel-Soycan) 1989 - IT-Monza (Masera) 2001 - CZ-Prague (Starý) 2011 - PL-Gdansk (Kowalczyk) 1990 - AT-Baden (Gadner) 2002 - HU-Budapest (Magyarosy) 2012 - CL-Santiago (Campbell) 1991 - FR-Annecy (Philippe) 2003 - FR-Paris (Cavé) 2013 - DE-Kiel (Schrappe) 1992 - NL-Den Haag (Kamps) 2004 - DE-Celle (Schrappe) 2014 - CZ-Prague (Starý) 1994 - DE-Berlin (Henze) 2005 - AT-Wien (Gadner) 2015 - HU-Budapest (Kovács) 1996 - BE-Gent (Benoît) 2006 - NL-Noordwijkerhout (Kaspers) 2016 - GR-Athens (Kosmidis) 1997 - DE-Freiburg (Niemeyer) 1998 - CH -Zürich (Pluess)

2007 - BE-Bruges (Benoît) 2008 - GB-Glasgow (Gibson)

2017 - IL -Jerusalem (Stark)

About Childhood Leukemia and Lymphoma Symposium (CLLS) The tradition of Biennial Childhood Leukemia Symposia (CLS) was established in the late 90s in Hannover, Germany. Since 2004, this symposia have been interconnected with the I-BFM-SG meetings (CLS takes places every other year), offering an unique chance to discuss the latest progress in childhood leukemia in an open forum of pediatric hematologists and oncologists from all over the world. The Symposium has a standard congress structure composed of single oral session, invited talks by top experts in the field are combined with free communications and poster session. The name of the CLS was changed for 2018 on Childhood Leukemia and Lymphoma Symposium (CLLS).

European Working Groups on Childhood Myelodysplastic syndrome (EWOG-MDS) and Severe Aplastic Anemia (EWOG-SAA) will actively participate in CLS organizing the session on myelodysplastic syndrome and bone marrow failures.

Organisation I-BFM SG Chairman Prof. Andrea Biondi

I-BFM SG Local Chairman Associate Prof. Jukka Kanerva Children's Hospital, Helsinki University Central Hospital, Helsinki, Finland

Meeting Secretariat C-IN 5. května 65, CZ-140 21 Prague 4, Czech Republic Tel: +42 (0) 261 174 304 Fax: +42 (0) 261 174 307 E-mail: info@ibfm2018.org Web: www.c-in.eu Karel Ježek (Senior Project Manager) E-mail: karel.jezek@c-in.eu Jana Dvořáková (Sponsorship Manager) Tel: +42 (0) 777 791 252 E-mail: jana.dvorakova@c-in.eu

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I-BFM Committees Committee Full Name Chair ALL Acute Lymphoblastic Leukemia Vora, Ajay AML Acute Myeloid Leukemia Hasle, Henrik B&D Biology & Diagnosis Trka, Jan CML Chronic Myeloic Leukemia Suttorp, Meinolf ECT Early Clinical Trials Zwaan, Michel ELTEC Early and Late Toxicity-Education Bardi, Edit IMM Information Management and Methodology De Lorenzo, Paola NHL Non-Hodgkin Lymphoma Attarbaschi, Andishe ResD Resistant Disease Hoogerbrugge, Peter SCT Stem Cell Transplantation Balduzzi, A.

I-BFM Study Groups Country Chair Study Group Argentina Freigeiro, Daniel GATLA Argentina Felice, Maria Sara SAHOP Australia Dalla-Pozza, Luciano; Strong, Robyn ANZCHOG Austria Dworzak, Michael BFM-A Belgium Benoit, Yves CLCG-EORTC Bulgaria Konstantinov, Dobrin Chile Campbell, Myriam PINDA China Li, Chi-Kong HKPHOSG Croatia Bilic, Ernest Czech Republic Stary, Jan CPH Finland Lähteenmäki, Päivi NOPHO

(NOPHO countries: Denmark, Finland, Iceland, Lithuania, Norway, Sweden) France Bertrand, Yves CLCG-EORTC France Baruchel, André FRALLE Germany Schrappe, Martin BFM-G Greece Kosmidis, Helen HESPHO Hungary Kovács, Gabor Israel Elitzur, Sara INS Italy Conter, Valentino AIEOP Japan Manabe, Atsushi JPLSG Netherlands Kollen, Wouter J.W. DCOG Poland Kowalczyk, Jerzy PPLLSG Serbia Kuzmanovic, Milos Slovakia Kolenova, Alexandra Slovenia Jazbec, Janez Spain Dapena, José Luis; Rives, Susana SEHOP Switzerland Bourquin, Jean-Pierre SPOG Turkey Soycan, Lebriz Ukraine Donskaya, Svetlana United Kingdom Vora, Ajay CCLG Uruguay Castillo, Luis

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Venue Scandic Grand Marina Address: Katajanokanlaituri 7, 00160 Helsinki, Finland Phone: +358 9 1666 1 Website:

This comfortable and refurbished hotel is located by the sea in the idyllic Katajanokka district, right next to the Market Square and Helsinki city centre.

The hotel and adjacent conference centre can accommodate up to 2,500 people in 18 flexible meeting rooms.

About Helsinki

Helsinki is a modern city, with half a million residents, nicely situated by the Baltic Sea. Helsinki is the center of Finland’s administrative, educational and cultural life. It is also the finance and business center of the country. Together with its neighboring cities Helsinki forms the metropolitan area with more than one million inhabitants.

Helsinki is a city full of contrasts: light and white in summer, and dark, but full of warmth in winter; modern and cutting edge, yet steeped in fascinating past; cosmopolitan and compact capital where form follows the function, where both sea and deep forests are just a stone’s throw away. Helsinki is unique among the Northern European cities. The lifestyle in the second-most northern capital city in the world is full of contrasts and activities also in the form of hundreds of events and friendly people.

Helsinki’s identity has been formed by cultural influences from both the East and West. Over 450 years of history, several architectural layers and the impact of different periods can clearly be seen in the city. The beauty of the surrounding nature blends seamlessly together with high-tech achievements and design, while old traditions mix with the latest contemporary trends.

Everything is nearby – Helsinki is a pocket-sized metropolis that is ideal for visitors!

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Airport

Helsinki Airport (IATA code: HEL), also known as Helsinki - Vantaa Airport is located in the city of Vantaa, 17 km north of Helsinki. Is the main airport of Finland that serves Helsinki metropolitan region. It is also a popular transfer point between Asia and Europe, due to it's geographical location and fast and easy transfers.

It was originally built for the 1952 Summer Olympic Games. In 2013, the airport served 15 Million passengers, being the fourth busiest airport in the Nordic countries and the 30th busiest airport in Europe. Is considered one of the best airports in Europe by some surveys.

How to get between the airport and the city center By Train

Local trains I and P operate between Helsinki Airport and the city centre on the Ring Rail Line. The journey time between the airport and the city centre (Central Railway Station) is approximately half an hour. A regional ticket costs 5,50 euros and can be purchased from Helsinki Region Transport (HSL) ticket machines.

By Bus

The Finnair City Bus operates between the airport and city centre (Elielinaukio) every 20 minutes and takes around 30 minutes. A single ticket costs 6.20 euros when purchased online in advance or 6.30 euros from the driver.

Bus 615 (“Lentoasema-Rautatientori”) is operated by Helsinki Region Transport (HSL). A regional ticket costs 5,50 euros and can be purchased from Helsinki Region Transport (HSL) ticket machines or from the driver with cash. At night you can also take the 415N night bus.

By Taxi

You can also travel conveniently between the airport and the city centre by taxi, which will cost around 45 euros.

Important Deadlines Overview Deadline for the main partners’ enrolment: Gold Partner 1 November 2017 Deadline for the partners’ enrolment: Silver and Bronze Partner 10 December 2017 We recommend reserving the accommodation by 1 February 2018 Deadline for exhibitors’ enrolment 1 April 2018 Deadline for printed advertisements 15 April 2018

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Partnership Categories Partners supporting the Meeting to a certain value will fall into different levels of Partnership categories as follows:

Gold Partner 20 000 € The Gold Partner will be offered the following benefits: • Satellite Symposium (60 minutes timeslot before or after the Meeting) • 12 sqm Exhibition space (additional space will be charged at a special rate of 200 EUR per sqm) and

priority of booth location choice • Complimentary Meeting registrations and tickets to Gala dinner: 5 • Full page advertisement in programme book • Premium placement of the Partner’s logo and URL on the official website, • Insert into delegate bags • Description (max. of 200 words) in the programme book • Permission to use the sponsorship of the Meeting for own advertising

Silver Partner 15 000 € The Silver Partner will be offered the following benefits: • Satellite Symposium (45 minutes timeslot before or after the Meeting. Timing dependent from the

choice of the Gold partner) • 9 sqm Exhibition space (additional space will be charged at a special rate of 200 EUR per sqm) and

priority of booth location choice after Gold Partner • Complimentary Meeting registrations and tickets to Gala dinner: 3 • Half page advertisement in programme book • Premium placement of the Partner’s logo and URL on the official website • Insert into delegate bags • Description (max. of 100 words) in the programme book • Permission to use the sponsorship of the Meeting for own advertising

Bronze Partner 7 500 € The Bronze Partner will be offered the following benefits: • 6 sqm Exhibition space (additional space will be charged at a special rate of 200 EUR per sqm) and

priority of booth location choice after Silver Partner • Complimentary Meeting registration and ticket to Gala dinner: 1 • Listing Bronze Partner including the partner’s logo in all convention publications and the website • Premium placement of the Partner’s logo and URL on the official website • Insert into delegate bags • Description (max. of 100 words) in the programme book • Permission to use the sponsorship of the Meeting for own advertising

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Individual Sponsorship Options Meeting Programme Book The Final Programme will be provided on site at the Meeting to all registered delegates including speakers, official guests, and exhibitors.

• Advertisement on inner full page 1 000 €

• Advertisement on inside front or inside back cover page 1 200 €

• Advertisement on outside back cover page 1 500 €

Meeting Bags One bag including Meeting materials will be distributed to all full registered delegates as they arrive on site at the Meeting. As a partner of the Meeting bags, you will have your company logo printed in a prominent position on the bag along with the Meeting logo. (Type, size and colour of the bags as well as position and size of the logo will be at the organizer discretion).

• Meeting and Symposium bags (exclusivity) 5 000 €

Badge Lanyards Sponsorship Each delegate will be given a lanyard with a name badge indicating their name and affiliation, this acting as identification pass throughout the Meeting. The sponsor’s logo will be printed on the lanyard and the Meeting logo will be printed on the name badge. If the company wishes to provide their own lanyards the partnership amount will be reviewed together with the sponsoring company.

• Lanyards (exclusivity) 3 000 €

Badges Sponsorship Logo of the sponsor will be placed on the front side of the delegate badge with the logo of the Meeting. Size and position will be confirmed by the Meeting organizer.

• Value 2 000 €

Annual Report The Annual Report 2017 of the I-BFM will be produced as USB flash drive. As a partner, the 500 USB flash drives with your logo will be distributed among all registered participants.

• Value 3 000 €

Inserts in Delegate ‘s Bags The opportunity is offered to partners to either provide (Already included in Golden and Silver partner package): An insert: an A4 size double-sided, colour or black and white flyer/promotional piece. This flyer could be text only promoting activities on your exhibition stand or it may be an existing corporate flyer of information on your services or products.

• Rate per insert 1 000 € Writing pads and/or pens with the logo of your company along with the Meeting logo. Delegates particularly appreciate to get writing pads and pens very useful for the scientific sessions. Pens and pads provided by the partner.

• Rate for writing pads and pens insertion 1 000 €

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Signage

Role of the signage is to welcome and navigate delegates during the Meeting to the venue and inside the venue. It is the very first thing what a delegate sees even before entering the Meeting building. Partner will be listed on the coloured navigation boards and in the acknowledgement in the Final Programme, on the Meeting and the Symposium website.

• Signage with the partner’s logo (exclusivity) 3 000 €

Internet Corner

Give each delegate the opportunity to access home and office e-mails. The sponsorship of this item consists of having your company logo on each computer screen background and screen saver. Company’s own branded mouse pads and other related promotional gifts in the internet corner area are an additional option. Such a great opportunity to have an immediate visual impact!

• Internet corner full financial participation 2 500 €

Poster or Banner in front of the Meeting Halls

Companies may also advertise their products and research through their poster or banner in the exhibition area or foyer of the meeting halls.

• Poster or banner placed in the venue of the meeting 1 500 €

Staff Polo Shirt

Meeting staff will wear a polo shirt with the logo of the Meeting and the sponsor. Staff at the registration, hostesses and technical support in the meeting rooms.

• Duration of the whole Meeting 1 500 €

Public Water Fountains

Water fountains for the delegates will be placed in all public areas for the whole Meeting and period. In case you decide to sponsor this item your company logo will be placed on every crucible and on the water tanks as well.

• Sponsoring for the duration of the Meeting 1 500 €

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Lunches

Lunch sponsorship package includes the opportunity to hang your company’s banner and distribute the napkins with your company’s logo in the lunch area.Sponsor will be listed in the acknowledgement in the Final Programme, on the Meeting and the Symposium website and on the sponsorship banner in the main meeting hall during the Opening and Closing Ceremony.

• One day lunch sponsorship 5 000 €

Coffee Breaks Coffee breaks sponsorship package includes the opportunity to hang your company’s banner and distribute the napkins with your company’s logo in the coffee break area. Sponsor will be listed in the acknowledgement in the Final Programme, on the Meeting and the Symposium website and on the sponsorship banner in the main meeting hall during the Opening and Closing Ceremony.

• One day coffee break sponsorship (2 x CB AM/PM) 3 500 €

Welcome Reception All delegates, accompanying persons and exhibitors are cordially invited to join the Meeting Welcome Reception taking place in the venue, right after the meeting Opening Ceremony. A pleasant and informal opportunity for the whole community to meet the industry. The sponsor name/logo is displayed in the welcome cocktail area and the sponsor will be listed in the acknowledgement in the Final Programme, on the Meeting and the Symposium website and on the sponsorship banner in the main meeting hall during the Opening and Closing Ceremony.

• Participation as a sponsor 10 000 €

Meeting Dinner The Meeting Dinner is an integrated and prestigious part of the official programme of the Meeting. All registered participants of IBFM are invited to join the Meeting Dinner. The location will be announed soon. Sponsor will be listed in the acknowledgement in the Final Programme, on the Meeting and the Symposium website and on the sponsorship banner in the main meeting hall during the Opening and Closing Ceremony.

• Exclusive sponsor 15 000 €

Hospitality Suites / Meeting Rooms An opportunity to hire a room at the Meeting venue that will be used as a Hospitality Suite. Supporter will be able to host and entertain its guests throughout the Meeting. Supporters will have the option to order catering at an additional cost. Opportunity to brand the hospitality suite. Acknowledgement on directional signage outside suite.

• Hospitality Suite for the duration of I-BFM 4 500 €

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Special Sponsorship Options for Childhood Leukemia and Lymphoma Symposium (CLLS) Main Symposium Partner (exclusively) 10 000 € SOLD

The Main Symposium Partner will be offered the following benefits: • Satellite Symposium (45 minutes timeslot during the lunch break or after the symposium in the main

plenary hall) • 6 sqm Exhibition space (additional space will be charged at a special rate of 200 EUR per sqm) also for

the duration of IBFM meeting • Complimentary Symposium registrations and tickets to Symposium dinner: 3 • Half page advertisement in programme book • Premium placement of the Partner’s logo and URL on the official website, • Insert into delegate bags • Description (max. of 100 words) in the programme book

Scientific Session Partner The opportunity to support the part of the Symposium programme. The support will be used to cover the expenses for invited speakers. The sponsor can suggest a speaker for the session. Sponsor will be listed in the all partners acknowledgement and also in the scientific programme and can place his own company banner in the meeting hall.

• Value 4 000 €

Symposium Dinner The Symposium Dinner is an integrated and prestigious part of the official programme of the Symposium. All registered participants of CLLS are invited to join the Symposium Dinner. The opportunity to meet students and professors together. Sponsor will be listed in the all partners acknowledgement and can place his own company banner in the venue of the dinner.

• Value 5 000 €

Abstract Book The Abstract Book of CLS will be produced as USB flash drive. Each participant will receive an exchange voucher in their registration kit so they could pick up the flash drive at your exhibition booth (USB may be distributed at registration desk – depends on the sponsor’s preference).

• Value 2 500 €

Poster Boards Poster area belongs to the most visited Symposium attractions. Partner’s name and logo will be attached on the frame of each poster board and in the acknowledgement in the Final Programme, on the Meeting and the Symposium website.

• Sponsoring for the duration of the Symposium (exclusivity) 2 200 €

Symposium Programme Book Advertisement The Final Programme (A5 format) will be provided on site at the Symposium to all registered delegates including speakers, official guests, and exhibitors.

• Advertisement on inner Full page 350 €

• Advertisement on inside front or inside back cover page 450 €

• Advertisement on outside back cover page 500 € SOLD

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Exhibition Part of the Meeting and Symposium will be the exhibition of industry partners that will create a unique opportunity to display and advertise the latest products, services and technical innovations.

• Price of 1 sqm of the exhibition space 350 €

• Table top (special package of table + 2 chairs) 1 000 €

Companies may apply for the exhibit space by returning the form “Exhibition Registration form”.

Exhibit place will be assigned by the organisers based on the stand space applications - first to the Gold, Silver and Bronze partners. However final allocation to main partners is to be determined no earlier than 31 January 2018. After this date the spaces will be offered to all other companies according to the space size request and on a first come – first served basis.

All prices are indicated VAT EXCLUDED. If you have a specific concept or wish other than mentioned above, please contact the Meeting Secretariat:

Jana Dvořáková C-IN, Prague Congress Centre, 5. května 65, 140 21 Prague 4, Czech Republic Tel: +420 261 174 304, GSM: +420 777 791 252 E-mail: jana.dvorakova@c-in.eu, Web: www.c-in.eu