grand round sampling of interesting dermatopathology cases

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  • 7/29/2019 Grand Round Sampling of Interesting Dermatopathology Cases

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    Sampling of a few interesting dermatopathology cases

    from CUMC

    Belly button fuzz ball, red

    palms, non-fitting prostheticleg, red wine glass etc.

    Deba P Sarma, MD

    Director of Dermatopathology

    Creighton University Medical Center

    Dept Pathology, Omaha

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    Dermatopathology articles from

    CUMC Dept of Pathology

    2006 to 2009

    Total: 59

    Pubmed indexed: 15Non-Pubmed indexed: 44

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    A 55-year-old obese woman

    4-month history of hemorrhagicdischarge from the umbilicus

    8-mm dark mass from baseof the umbilicus

    Case 1

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    Diagnosis: Lint ball omphalitis

    Ref:

    Sarma DP,Teruya B (2009). Lint ball omhphalitis, a

    rare cause of umbilical discharge in an adult woman: a

    case report. Cases J 2: 7785 PMID:19830013.[Pubmed-indexed for MEDLINE].

    Steinhauser G (2009).The nature of navel fluff. MedHypotheses. 72(6):623-5.

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    50-year-old man

    Possible pilar cyst removed from scalp.

    Case 2

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    RCC immunostain

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    Implantation carcinoma of the scalp from renal

    cell carcinoma

    Ref:

    Sarma DP, Wang JF, McAllister MV, Wang B, Shehan

    JM. (2008) Possible implantation carcinoma of the scalp

    following craniotomy for metastatic renal cellcarcinoma. Dermatology Online J 14(6):20. PMID:

    18713600 [PubMed - indexed for MEDLINE]

    Diagnosis:

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    44-year old man of Chinese heritage whohad red hands since birth

    74-year-old mother and 7-year-old daughteralso had bright red palms all their life

    Case 3

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    Erythema palmare hereditarium

    (Red palm disease, Lanes disease)

    Ref:Sarma DP, Wang B (2007). Erythema palmarehereditarium (Red palms): Lanes Disease. DermatolOnline J. 13(2). PMID: 17498447 [PubMed - indexed for MEDLINE]

    Lane JE. Erythema palmare hereditarium. Arch DermSyph. 1929; 445-448.

    Diagnosis

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    58-year-old man with left knee dislocation with

    neurovascular injury in 1968.

    Left below the knee amputation, fitted with an artificialleg.

    36 years later in 2004, pain at the amputation site, mass,foul discharge.

    Case 4

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    Verrucous carcinoma in the amputation stump

    Ref:

    Sarma DP, Hansen TP, Adickes ED(2006):

    Carcinoma arising in the leg amputation stump.

    The Internet J Dermatol 4(1). Indexed in

    Google Scholar.

    Diagnosis

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    Sarma DP, Weilbaecher TG. Carcinoma arising in burn scar.

    J Surg Oncol. 1985 Jun;29(2):89-90.

    A 60-year-old man had Lt BK amputation 30 years ago after adynamite explosion injury.

    Artificial leg since then.

    Developed squamous cell carcinoma on the amputation stump30 years later.

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    Three skin biopsies from the face of three

    men (age: 55-67yrs)

    Case 5

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    Winer L H. The dilated pore, a trichoepithelioma. J

    Invest Dermatol 1954; 23(3):181-188.

    Sarma Deba P.(2009): Dilated Pore of Winer, Dr. LouisH Winer and Wine Glass. The Internet Journal of

    Dermatology Vol 7(2).

    Ref

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    Woman, 32 yrs

    5 mm, painless subareolar nodule, left breast

    Case 6

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    Diagnosis:

    Infiltrating syringomatous eccrine

    adenoma of the nipple

    Ref:

    Sarma D, Stevens T (2009). Infiltrating syringomatouseccrine adenoma of the nipple: a case report. Cases J 2:0118.

    PMID:20062695 [Pubmed-indexed for MEDLINE]

    C 7

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    Case 7

    83-yr-old female, 7-mm painless soft papule, left

    cheek, present for few months

    Clinical lipoma

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    CK 20Chromogranin Synaptophysin

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    Diagnosis:

    Subcutaneous Merkel cell carcinoma

    Ref

    Sarma DP, Heagley D, Chalupa J, Cox M, Shehan JM.

    An unusual clinical presentation of Merkel cell

    carcinoma. Case Reports in Medicine