gnipst bulletin 26.3
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28th
June, 2013 Volume No.: 26 Issue No.: 03
ContentsMessage from GNIPS
Letter to the EditorNews Update
Health awareness
Disease Outbreak Ne
Forth Coming Events
Drugs Update
Campus News
Students Section
Editors Note
Archive
Vision
TO GROW AS A CENTRE OF EXCELLENCE IN THE FIELD O
PHARMACEUTICAL AND BIOLOGICAL SCIENCE
EDITOR: Soumya Bhattacharya
GURU NANAK INSTITUTE OF PHARMACEUTICAL SCIENCE ANDTECHNOLOGY
GNIPST Photo Gallery
For your comments/contributionORFor Back-Issues,
mailto:[email protected]
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MESSAGE FROM GNIPSTGNIPST BULLETIN is the official publication of Guru Nanak
Institute of Pharmaceutical Science & Technology. All the
members of GNIPST are proud to publish the 26th
Volume of
GNIPST BULLETIN. Over the last two years this bulletin
updating readers with different scientific, cultural or sports
activities of this prestigious institute and promoting knowledge of
recent development in Pharmaceutical and Biological Sciences.
Students section is informing readers about some curious facts of
drug discovery, science, sports and other relevant fields. We look
forward to seeing your submission and welcome comments and
ideas you may have.
LETTER TO THE EDITOR.
NEWS UPDATE
International Day Against Drug Abuse and Illicit
Trafficking :26 June,2013
The International Day Against Drug Abuse and Illicit Trafficking on
26th june . this day is observed with United Nation coordiation to
strengthen action and cooperation to achieve the goal of an
international society free of drug abuse. The theme of this year is
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"Make health your 'new high' in life, not drugs" aims to inform the
public and particularly young people, about the harmful effects of
new psychoactive substances (NPS) or legal high substances. Today,
there is an alarming new drug problem; demand has soared for
substances not under international control. veryone has a part to play
in protecting the youth of the world from dangerous substances.
UNODC leads the annual World Drug Campaign to drive home the
message that illicit drugs pose a danger to society, aims to mobilize
wide public support and seeks to inspire people to act against drugabuse. Read more
Gene mutation may have effect on benefit of
aspirin use for colorectal cancer(25th June, 2013)According to recent clinical trials, the association between aspirin use
and risk of colorectal cancer was affected by mutation of the gene
BRAF, with regular aspirin use associated with a lower risk of BRAF-
wild-type colorectal cancer but not with risk of BRAF-mutated
cancer. The findings suggest that BRAF-mutant colon tumor cells
may be less sensitive to the effect of aspirin.Read more
Novel therapy to treat Muscular Dystrophy (25th June,
2013)Researchers at Boston University College of Health & Rehabilitation
Sciences: Sargent College have identified a combinatorial therapeutic
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approach that has proven effective in treating muscular dystrophy in a
mouse model.Read more
Antibiotic shows analgesic action following surgery(25th June, 2013)
Researchers at university Sapienza in Rome analyzed that a single
dose of the antibiotic Ceftriaxone given for antimicrobial prophylaxis
prior to surgery enhanced patient pain thresholds after the procedure.
Read more
Computerized brain fitness program improves the
memory of older adults(25th June, 2013)
Researchers have found that older adults who regularly used a brain-
fitness program called Dakim Brain Fitness on a computer
demonstrated significantly improved memory and language skills.
Read more
Nano goldfor vaccine development (25th June, 2013)US scientists have developed a novel vaccination method that uses
tiny gold particles to mimic a virus and carry specific proteins to the
body's specialist immune cells. The technique differs from the
traditional approach of using dead or inactive viruses as a vaccine and
was demonstrated in the lab using a specific protein that sits on the
surface of the respiratory syncytial virus (RSV).Read more
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New Palm-Sized Microarray Technique Grows
1,200 Individual Cultures of Microbes(25th June, 2013)Scientists at the University of Texas at San Antonio and the U.S.Army Institute of Surgical Research at Fort Sam Houston have
developed a microarray platform for culturing fungal biofilms, and
validated one potential application of the technology to identify new
drugs effective against Candida albicans biofilms.Read more
Zebra fish Study Paves the Way for NewTreatments for Genetic Disorder(26th June, 2013)
A research project conducted at the Sheffield Institute for
Translational Neuroscience (SITraN) and the MRC Centre for
Developmental and Biomedical Genetics (CDBG) by Dr Andrew
Grierson and his team has revealed that zebrafish could hold the key
to finding new therapeutic approaches to treat Charcot Marie Tooth
disease (CMT), a genetic disorderRead more
Simple Two-Drug Combination Proves Effective in
Reducing Risk of Stroke (26th June, 2013)
Results of a Phase III clinical trial showed that a simple drug regimen
of two anti-clotting drugs - clopidogrel and aspirin lowered the risk
of stroke by almost one-third, compared to the standard therapy of
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aspirin alone, when given to patients who had minor or transient
stroke symptoms to prevent subsequent attacks.Read more
HEALTH AWARENESS
Drug Abuse-A Psychosocial Disorder
Substance abuse or Drug abuse is a complex and multifactorial
disorder involving individual, cultural, biological, social and
environmental factors. Substance abuse refers to the harmful or
hazardous use of psychoactive substances, including alcohol and
illicit drugs. Psychoactive substance use can lead to dependence
syndrome which includes behavioural, cognitive, and physiological
phenomena that develop after repeated substance use and that
typically include a strong desire to take the drug, difficulties in
controlling its use, persisting in its use despite harmful consequences,
a higher priority given to drug use than to other activities andobligations, increased tolerance, and sometimes a physical
withdrawal state.
The World Drug report (UNODC 2009) estimates the
total number of people using illicit drugs at upwards of 250 million
peopleequivalent to about 4 per cent of the global population aged
15 to 64. Of that number, as many as 38 million people are drug
dependent, but only about 4.9 million of them receive evidence-based
drug dependence treatment and care.
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Glues
Paint thinner
Gasoline
Laughing gas
Aerosol sprays
Cannabinoids:
These drugs result in feelings of euphoria, cause confusion and
memory problems, anxiety, a higher heart rate, as well as staggering
and poor reaction time.
Types of drugs include:
Hashish
Marijuana
Depressants:
Depressants slow down activity in the central nervous system of your
body. These drugs are also called downers because they slow the
body down and seem to give feelings of relaxation. Depressants are
available as prescription drugs to relieve stress and anger, although
drowsiness is often a side effect. The relaxation felt from these drugs
is not a healthy feeling for the body to experience, to stop abuse of
this drug, drug treatment is suggested.
Types of drugs:
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Barbiturates
Benzodiazepines
Flunitrazepam
GHB (Gamma-hydroxybutyrate)
Methaqualone
Alcohol
Tranquillisers
Hallucinogens
When taking hallucinogens, switching emotions is frequent. These
drugs change the mind and cause the appearance of things that arenot really there. Hallucinogens affect the bodys self-control, such as
speech and movement, and often bring about hostility. Other negative
side effects of these drugs include heart failure, increased heart rate,
higher blood pressure and changes in the bodys hormones.
Types of drugs include:
LSD (lysergic acid diethylamide)
Mescaline
Psilocybin
Cannabis
Magic Mushrooms
Prescription Drugs
Prescription drugs can be very helpful drugs when used properly and
when under the guidance of a qualified physician. These drugs can be
used as aids in surgery, to treat medical conditions and while
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controlling various symptoms. Misuse and abuse of prescription
drugs however can be very dangerous.
Types of drugs include:
Opiods: Codeine, Oxycodone, Morphine
Central nervous system depressants: barbiturates, benzodiazepines
Stimulants: dextroamphetamine, methylphenidate
Common signs and symptoms of substance abuse:
Physical Symptoms: Glazed eye, Drowsiness, Runny nose,
Coughing, Needle marks, Weight loss, Malnutrition, Tremor,
Hallucination etc.
Emotional and social signs :
Moodiness, excitement, anger, hostility, depression
Constant lying and stealing
Refusing to admit to the harmful effects of drugs
Avoiding old friends or people who could confront them
about behavior changes
Being secretive about phone calls
Having friends they do not want you to meet or talk about
Being evasive about their whereabouts
Loss of motivation
No interest in everyday life
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Playing truant from school
Treatment strategies for substance abuse:
Drug dependence is as much a disorder of the brain as any other
neurological or psychiatric illness. One of the main barriers to
treatment and care is the stigma and discrimination associated with
this treatable health disorder. The major two approaches for the
treatment of substance abuse are
Psychosocial therapy: behavioral therapy, motivational therapy,
cognitive therapy, family therapy, social engagement
Pharmacotherapy: use of opioid agonist or use of some antagonist
(disulfiram for alcohol)
Impact of substance abuse on society and health:
The negative consequences of drug abuse affect not only individualswho abuse drugs but also their families and friends, societies, and
government resources.
The most obvious effects of drug abuse which are manifested in the
individuals who abuse drugs include ill health, sickness and,
ultimately, death.
Injecting drug abuser is more prone to needle borne infection like
hepatitis and HIV AIDS.
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Children of individuals who abuse drugs often are abused or
neglected as a result of the individuals' preoccupation with drugs.
Children whose parents and other family members abuse drugs oftenare physically or emotionally abused and often lack proper
immunizations, medical care, dental care, and necessities such as food,
water, and shelter.
The risk to children is even greater when their parents or guardians
manufacture illicit drugs such as methamphetamine.
Methamphetamine abusers often produce the drug in their own
homes and apartments, using hazardous chemicals such as hydriodic
acid, iodine, and anhydrous ammonia. Children who inhabit such
homes often inhale dangerous chemical fumes and gases or ingest
toxic chemicals or illicit drugs.
Alcohol use contributes to a wide range of diseases, health conditions
and high-risk behaviours, from mental disorders and road traffic
injuries, to liver diseases and unsafe sexual behaviour.
The economic impact of drug abuse on businesses whose employees
abuse drugs can be significant. While many drug abusers are unable
to attain or hold full-time employment, those who do work put others
at risk, particularly when employed in positions where even a minor
degree of impairment could be catastrophic; airline pilots, air traffic
controllers, train operators, and bus drivers are just a few examples.
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Drug or substance abuse is a social cancer. It is essential to stop
the further proliferation of this evil disorder. Only a pro-life attitude
of young generations can break this age old psychosocial dogma.
Source:
World Health Organization
UNODC
Narcotic Control Bureau, India
DISEASE OUTBREAK NEWS
Middle East respiratory syndrome corona virus
(MERS-CoV)(26thJune, 2013)
The Ministry of Health (MoH) in Saudi Arabia has announced seven
additional laboratory-confirmed cases and a death in a previously
confirmed case of Middle East respiratory syndrome coronavirus
(MERS-CoV).Read more
FORTHCOMING EVENTS
A Teachers Development Programme for SchoolTechers will be organized by GNIPST on 29th June, 2013
at college auditorium. The theme of the programme is
Recent Trends of Life Sciences in Higher Education
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Two short-term (2 weeks each) AICTE-sponsored refresher
courses on: Innovation and excellence in Pharmaceutical Sciences for
teaching staffs of the Indian Universities and colleges in QIP Nodal
Cell (Pharmacy), Department of Pharmaceutical Technology,
Jadavpur University, Kolkata-700 032 from 2nd July to 29th
July,2013.Read more
AICTE Sponsored Quality Improvement Programme on
Production to Prescription - Opportunities for Innovation on
MCOPS, Manipal University from 1-13th July, 2013.Read more
DRUGS UPDATES
FDA approves Vibativ for hospitalized patients with
bacterial pneumonia (21st June)The U.S. Food and Drug Administration today expanded the
approved use of the antibiotic Vibativ (telavancin) to treat patients
with hospital-acquired and ventilator-associated bacterial pneumonia(HABP/VABP) caused by Staphylococcus aureus. Vibativ should be
used for the treatment of HABP/VABP only when alternative
treatments are not suitable.Read more
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FDA approves Xgeva to treat giant cell tumor of
the bone (13th June, 2013)
The U.S. Food and Drug Administration today expanded theapproved use of Xgeva (denosumab) to treat adults and some
adolescents with giant cell tumor of the bone (GCTB), a rare and
usually non-cancerous tumor.Read more
CAMPUS NEWS
The following B.Pharm. final year students have qualified, GPAT-
2013. We congratulate them all.
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STUDENTS SECTION
WHO CAN ANSWER FIRST???
Which drug was first synthesized by C.R.A.Wright in 1984 ?
Which drug was first isolated by R. Mechoulamand Y .Gaoni?
Answer of Previous Issue Question:A)Albendazole B)Ancylostoma
Send your thoughts/ Quiz/Puzzles/games/write-ups or any other contributions for Students Section
& answers of this Section [email protected] NOTE
I am proud to publish the 3rd
issue of 26th
Volume of GNIPST
BULLETIN. GNIPST BULLETIN now connected globally through
facebook account GNIPST bulletin
I want to convey my thanks to all the GNIPST members and the
readers for their valuable comments, encouragement& supports.
I am thankful to Dr. Abhijit Sengupta, Director of GNIPST and
Prof. Dipankar Chakraborty, Registrar of GNIPST for their
valuable advice and encouragement. Special thanks to Dr. Prerona
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Saha andMr. Debabrata Ghosh Dastidar for their kind co-operation
and technical supports.
An important part of the improvement of the bulletin is the
contribution of the readers. You are invited to send in your write ups,
notes, critiques or any kind of contribution for the forthcoming special
and regular issue.
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ARCHIVE
The general body meeting of APTI, Bengal Branch has been conducted
at GNIPST on 15
th
June, 2012. The program started with a nicepresentation by Dr. Pulok Kr. Mukherjee, School of Natural Products,
JU on the skill to write a good manuscript for publication in impact
journals. It was followed by nearly two hour long discussion among
more than thirty participants on different aspects of pharmacy
education. Five nonmember participants applied for membership on
that very day.
GNIPST is now approved by AICTE and affiliated to WBUT for
conducting the two years post graduate course (M.Pharm) in
PHARMACOLOGY. The approved number of seat is 18.
The number of seats in B.Pharm. has been increased from 60 to 120.
2nd World Congress on Ga-68 (Generators and Novel Radiopharmaceuticals),
Molecular Imaging (PET/CT), Targeted Radionuclide Therapy, and Dosimetry
(SWC-2013) : On the Way to Personalized Medicine
Dates 28 Feb 2013 02 Mar 2013
Location: Chandigarh, India.Details. AICTE has sanctioned a release of grant under Research Promotion
Scheme (RPS) during the financial year 2012-13to GNIPST as per the
details below:
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a. Beneficiary Institution: Guru Nanak Institution of Pharmaceutical
Science & Technology.
b. Principal Investigator: Dr. Lopamudra Dutta.
c. Grant-in-aid sanctioned :Rs. 16,25000/- only
d. Approved duration: 3 years
e. Title of the project: Screening and identification of potential
medicinal plant of Purulia& Bankura districts of West Bengal with
respect to diseases such as diabetes, rheumatism, Jaundice,
hypertension and developing biotechnological tools for enhancing
bioactive molecules in these plants.