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GlaxoSmithKline vs Pfizer UBI Business & Competitive UBI Business & Competitive Intelligence Intelligence Presentation by : Presentation by : Aksenov Yuri Aksenov Yuri Pascal Andrea Pascal Andrea Hendricx Chris Hendricx Chris Brussels, December 15th 2006 Brussels, December 15th 2006

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Page 1: GlaxoSmithKline vs Pfizer UBI Business & Competitive Intelligence Presentation by : Aksenov Yuri Pascal Andrea Hendricx Chris Brussels, December 15th 2006

GlaxoSmithKline vs Pfizer

UBI Business & Competitive IntelligenceUBI Business & Competitive Intelligence

Presentation by :Presentation by :

Aksenov YuriAksenov Yuri

Pascal AndreaPascal Andrea

Hendricx ChrisHendricx Chris

Brussels, December 15th 2006Brussels, December 15th 2006

Page 2: GlaxoSmithKline vs Pfizer UBI Business & Competitive Intelligence Presentation by : Aksenov Yuri Pascal Andrea Hendricx Chris Brussels, December 15th 2006

Key Intelligence Topic

The future of pharma: The future of pharma:

Prevent Prevent oror Cure Cure ??

Page 3: GlaxoSmithKline vs Pfizer UBI Business & Competitive Intelligence Presentation by : Aksenov Yuri Pascal Andrea Hendricx Chris Brussels, December 15th 2006

Analysis of key factors

Industry FiguresPlayers, market shares, evolution

Who are Pfizer and GSKPerformances, products, policies

Investors outlookIn depth analysis

Risks, Opportunities, Capabilities

Implications Recommendations

Strategies, positioning

ConclusionsSources

Page 4: GlaxoSmithKline vs Pfizer UBI Business & Competitive Intelligence Presentation by : Aksenov Yuri Pascal Andrea Hendricx Chris Brussels, December 15th 2006

*both companies are at the top

Top 10 Pharmaceuticals companies in the world

Analysis of key factorsAnalysis of key factors

Page 5: GlaxoSmithKline vs Pfizer UBI Business & Competitive Intelligence Presentation by : Aksenov Yuri Pascal Andrea Hendricx Chris Brussels, December 15th 2006

Top 10 markets evolution

Analysis of key factorsAnalysis of key factors

Page 6: GlaxoSmithKline vs Pfizer UBI Business & Competitive Intelligence Presentation by : Aksenov Yuri Pascal Andrea Hendricx Chris Brussels, December 15th 2006

Market segmentation

Analysis of key factorsAnalysis of key factors

Page 7: GlaxoSmithKline vs Pfizer UBI Business & Competitive Intelligence Presentation by : Aksenov Yuri Pascal Andrea Hendricx Chris Brussels, December 15th 2006

Company fact sheet

Corporate views and valuesCorporate views and values

Mission - to improve the quality of human life

Purpose – dedicated to better health and greater access to healthcare.

Research based pharmaceutical company

Shape a flexible R&D organisation that can respond to the challenges and the opportunities

Mission - become the world's most valued company to patients, customers, colleagues, investors, business partners.

Purpose – dedicated to better health and greater access to healthcare.

Growth through innovation

Research based pharmaceutical company

Page 8: GlaxoSmithKline vs Pfizer UBI Business & Competitive Intelligence Presentation by : Aksenov Yuri Pascal Andrea Hendricx Chris Brussels, December 15th 2006

Company fact sheet

CustomerCustomer understanding and responding to understanding and responding to

their often changing needs.their often changing needs.

Personnel policyPersonnel policy GSK business employs over 100,000 GSK business employs over 100,000

people in 116 countries people in 116 countries

Over 15,000 people work in research Over 15,000 people work in research teams to discover new medicinesteams to discover new medicines

For employees, we create an For employees, we create an environment that allows them to do environment that allows them to do their best work by being themselvestheir best work by being themselves

StakeholdersStakeholders we must provide the right we must provide the right

information in a timely and information in a timely and effective way.effective way.

CustomerCustomer deeply committed to meeting the needs deeply committed to meeting the needs

of our customers, and we constantly of our customers, and we constantly focus on customer satisfactionfocus on customer satisfaction

Personnel policyPersonnel policy Pfizer employs 122,000 people in 60 Pfizer employs 122,000 people in 60

countries and has sales in more than countries and has sales in more than 150 countries.150 countries.

People are the cornerstone of Pfizer's People are the cornerstone of Pfizer's success, we value our diversity as a success, we value our diversity as a source of strength, and we are proud source of strength, and we are proud of Pfizer's history of treating people of Pfizer's history of treating people with respect and dignitywith respect and dignity

StakeholdersStakeholders We work with stakeholders to We work with stakeholders to

share knowledge, skills and goals share knowledge, skills and goals on how to prevent or manage on how to prevent or manage diseases, how to get medicine to diseases, how to get medicine to the people who need it, and how the people who need it, and how to promote good health.to promote good health.

Corporate views and valuesCorporate views and values

Page 9: GlaxoSmithKline vs Pfizer UBI Business & Competitive Intelligence Presentation by : Aksenov Yuri Pascal Andrea Hendricx Chris Brussels, December 15th 2006

9147.74; 28%

5826.39; 17%

4702.38; 14%

2749.39; 8%

2705.95; 8%

2514.09; 7%

1838.96; 5%

2409.11; 7%

1882.4; 6%

Respiratory

Central nervous system

Anti-Virals

Anti-Bacterials

Metabolic

Vaccines

Oncology and emesis

Cardiovascular

Other

3538; 10%

5763; 15%

2633; 7%

1372; 4%

0; 0%

1669; 5%

2434; 7%

17958; 48%

1368; 4%

Respiratory

Central nervous system

Urology

Ophthalmology

Vaccines

Artrithis

Oncology and emesis

Cardiovascular

Other

Segment portfolio

Analysis of key factorsAnalysis of key factors

Page 10: GlaxoSmithKline vs Pfizer UBI Business & Competitive Intelligence Presentation by : Aksenov Yuri Pascal Andrea Hendricx Chris Brussels, December 15th 2006

FINANCIAL PERFORMANCE GSKFINANCIAL PERFORMANCE GSK FINANCIAL PERFORMANCE PFIZERFINANCIAL PERFORMANCE PFIZER

groupgroup groupgroup

   20032003 20042004 20052005       20032003 20042004 20052005   

SALESSALES 2107021070 1998619986 2166021660 PoundsPounds SALESSALES 4473644736 5251652516 5129851298 USDUSD

EBITEBIT 59545954 57795779 67326732 PoundsPounds EBITEBIT 32463246 1400714007 1153411534 USDUSD

PATPAT 43084308 40224022 48164816 PoundsPounds PATPAT 39403940 1136111361 80858085 USDUSD

EPSEPS 0.720.72 0.680.68 0.820.82 PoundsPounds EPSEPS 0.220.22 1.511.51 1.11.1 USDUSD

R&DR&D 28652865 29042904 31363136 PoundsPounds R&DR&D 74877487 76847684 74427442 USDUSD

SALES GROWTHSALES GROWTH ---- -5-5 88 %%SALES SALES GROWTHGROWTH ---- 1717 -2-2 %%

R&D growthR&D growth ---- 1.31.3 88 %% R&D growthR&D growth ---- -2.1-2.1 -0.1-0.1 %%

R&D as % of salesR&D as % of sales 13.613.6 14.514.5 14.514.5 %%R&D as % of R&D as % of salessales 16.716.7 14.614.6 14.514.5 %%

EBIT growthEBIT growth ---- -3-3 1616 %% EBIT growthEBIT growth ---- --*--* -18-18 % %

31%

22%

Analysis of key factorsAnalysis of key factors

Page 11: GlaxoSmithKline vs Pfizer UBI Business & Competitive Intelligence Presentation by : Aksenov Yuri Pascal Andrea Hendricx Chris Brussels, December 15th 2006

0%

10%

20%

30%

40%

50%

60%

70%

80%

90%

100%

Reseach 49% 89% 66% 79% 97% 61% 22% 8% 59% 68% 51% 16% 65%

PFE NVS RCH GSK LLY WYE JNJ BMS AVE MRK ABT SGP AZN

Source: Evaluate, Internal Analysis

Industry Supplements internal R&D with BD&L/M&A Activity

Analysis of key factorsAnalysis of key factors

Page 12: GlaxoSmithKline vs Pfizer UBI Business & Competitive Intelligence Presentation by : Aksenov Yuri Pascal Andrea Hendricx Chris Brussels, December 15th 2006

Investor outlook

Analysis of key factorsAnalysis of key factors

Page 13: GlaxoSmithKline vs Pfizer UBI Business & Competitive Intelligence Presentation by : Aksenov Yuri Pascal Andrea Hendricx Chris Brussels, December 15th 2006

Performance analysis, outlook

Analysis of key factorsAnalysis of key factors

• US continued to remain the largest market for pharmaceuticals in the worldUS continued to remain the largest market for pharmaceuticals in the world

•Pfizer, Sanofi-Aventis and GSK remained as the top three companies in terms of pharma Pfizer, Sanofi-Aventis and GSK remained as the top three companies in terms of pharma salessales • Three relatively smaller players namely Amgen, Abbott Labs and AstraZeneca, however, Three relatively smaller players namely Amgen, Abbott Labs and AstraZeneca, however, reported a double digit growth during 2005 with Amgen recording the highest growth reported a double digit growth during 2005 with Amgen recording the highest growth rate of 20.5 per cent. rate of 20.5 per cent.

• Pfizer's own sale in the US market fell by 11.8 per cent to 23.44 billion dollars in 2005 Pfizer's own sale in the US market fell by 11.8 per cent to 23.44 billion dollars in 2005 from 26.58 billion. from 26.58 billion.

•GSK’s US sales fell by 3.5 per cent during 2005. GSK’s US sales fell by 3.5 per cent during 2005.

•Eli Lilly stood out as the largest spender of R&D in 2005 with its spending of 20.7 per Eli Lilly stood out as the largest spender of R&D in 2005 with its spending of 20.7 per cent of gross turnover. Amgen, another relatively smaller player among the 15, has spent cent of gross turnover. Amgen, another relatively smaller player among the 15, has spent 18.6 per cent of its turnover on R&D. On the other hand, Pfizer's R&D expenditure 18.6 per cent of its turnover on R&D. On the other hand, Pfizer's R&D expenditure declined by 3.1 per cent to 7.44 billion dollars in 2005 from 7.68 billion.declined by 3.1 per cent to 7.44 billion dollars in 2005 from 7.68 billion.

•The pharma companies are taking this threat from the generic players quite seriously by The pharma companies are taking this threat from the generic players quite seriously by spending more on R&D. spending more on R&D.

Page 14: GlaxoSmithKline vs Pfizer UBI Business & Competitive Intelligence Presentation by : Aksenov Yuri Pascal Andrea Hendricx Chris Brussels, December 15th 2006

Sales

M&S

R&D

G&A

Price

Units

EBIT

Sales Units

Price

M&S

R&D

G&A

EBIT

Price Pressures limitsPrice Pressures limitsIndustry ability to use Industry ability to use

price for growthprice for growth

Industry continues toIndustry continues toconsolidate in order toconsolidate in order to

cut infrastructure costs:cut infrastructure costs:-Reduce sales reps Reduce sales reps - Eliminate TA areasEliminate TA areas

in Researchin Research-Reduce duplication in Reduce duplication in

support functionssupport functions

Consolidations protectsConsolidations protectsEarnings growth & Earnings growth &

Capital valueCapital value

Price pressures drive consolidations to maintain earning levelsPrice pressures drive consolidations to maintain earning levels

Analysis of key factorsAnalysis of key factors

Page 15: GlaxoSmithKline vs Pfizer UBI Business & Competitive Intelligence Presentation by : Aksenov Yuri Pascal Andrea Hendricx Chris Brussels, December 15th 2006

Overview

MethodologyMethodology RisksRisks OpportunitiesOpportunities ImplicationsImplications

Future Business Impact AssessmentFuture Business Impact Assessment

Page 16: GlaxoSmithKline vs Pfizer UBI Business & Competitive Intelligence Presentation by : Aksenov Yuri Pascal Andrea Hendricx Chris Brussels, December 15th 2006

Exclusively developed to study the two companies in their Exclusively developed to study the two companies in their competitive environment, understanding the impact of future competitive environment, understanding the impact of future events for their future business strategy.events for their future business strategy.

Each risk and opportunity assessed in its magnitude, considering Each risk and opportunity assessed in its magnitude, considering two additional company dimensions:two additional company dimensions:

Risk Opportunity

Likelihood Likelihood

Preparedness Capabilities

Exposure Attractiveness

The PHA® Model

Future Business Impact AssessmentFuture Business Impact Assessment

Page 17: GlaxoSmithKline vs Pfizer UBI Business & Competitive Intelligence Presentation by : Aksenov Yuri Pascal Andrea Hendricx Chris Brussels, December 15th 2006

Product Recall & Litigations Product Recall & Litigations Patent Expiration Patent Expiration BRIC Competition & GenericsBRIC Competition & Generics Free Access & Price Dumping Free Access & Price Dumping Public opinion pressurePublic opinion pressure

Events (risks)

Future Business Impact AssessmentFuture Business Impact Assessment

Page 18: GlaxoSmithKline vs Pfizer UBI Business & Competitive Intelligence Presentation by : Aksenov Yuri Pascal Andrea Hendricx Chris Brussels, December 15th 2006

Glaxo

0

1

2

3

4

5

6

0 1 2 3 4 5 6

Risk Exposure

Pre

par

edn

ess Product Recall & Litigations

Patent Expiration

Free Access & Price Dumping

BRIC Competition & Generics

Public Opinion Pressure

“Safe Zone”

“Danger Zone”

Bubble size denotes event likelihood

Risk assessment

Future Business Impact AssessmentFuture Business Impact Assessment

Page 19: GlaxoSmithKline vs Pfizer UBI Business & Competitive Intelligence Presentation by : Aksenov Yuri Pascal Andrea Hendricx Chris Brussels, December 15th 2006

Pfizer

0

1

2

3

4

5

6

0 1 2 3 4 5 6

Risk Exposure

Pre

par

edn

ess Product Recall & Litigations

Patent Expiration

Free Access & Price Dumping

BRIC Competition & Generics

Public Opinion Pressure

“Danger Zone”

“Safe Zone”

Bubble size denotes event likelihood

Risk assessment

Future Business Impact AssessmentFuture Business Impact Assessment

Page 20: GlaxoSmithKline vs Pfizer UBI Business & Competitive Intelligence Presentation by : Aksenov Yuri Pascal Andrea Hendricx Chris Brussels, December 15th 2006

Cancer TreatmentCancer Treatment Pandemic & BioterrorismPandemic & Bioterrorism Healthcare & AnimalHealthcare & Animal Online Pharmacy Online Pharmacy Developing WorldDeveloping World

Markets (opportunities)

Future Business Impact AssessmentFuture Business Impact Assessment

Page 21: GlaxoSmithKline vs Pfizer UBI Business & Competitive Intelligence Presentation by : Aksenov Yuri Pascal Andrea Hendricx Chris Brussels, December 15th 2006

Glaxo

0

1

2

3

4

5

6

0 1 2 3 4 5 6

Opportunity Attractiveness

Cap

abili

ties

Cancer Treatment

Healthcare & Animal

Pandemic & Bioterrorism

Online Pharmacy

Developing World

“Addressable”

“Missed”

Bubble size denotes market likelihood

Opportunity assessment

Future Business Impact AssessmentFuture Business Impact Assessment

Page 22: GlaxoSmithKline vs Pfizer UBI Business & Competitive Intelligence Presentation by : Aksenov Yuri Pascal Andrea Hendricx Chris Brussels, December 15th 2006

Pfizer

0

1

2

3

4

5

6

0 1 2 3 4 5 6

Opportunity Attractiveness

Cap

abilit

ies Cancer Treatment

Healthcare & Animal

Pandemic & Bioterrorism

Online Pharmacy

Developing World

“Addressable”

“Missed”

Bubble size denotes market likelihood

Opportunity assessment

Future Business Impact AssessmentFuture Business Impact Assessment

Page 23: GlaxoSmithKline vs Pfizer UBI Business & Competitive Intelligence Presentation by : Aksenov Yuri Pascal Andrea Hendricx Chris Brussels, December 15th 2006

Exposed to animal rights Exposed to animal rights activists and public opinion activists and public opinion pressure.pressure.

Betting on pandemic flu Betting on pandemic flu vaccine as next large pharma vaccine as next large pharma opportunity.opportunity.

Implications

Reliant on blockbusters and Reliant on blockbusters and over-the-counter over-the-counter medicaments.medicaments.

Heavily exposed to product Heavily exposed to product recall and BRIC competition recall and BRIC competition on generics.on generics.

Future Business Impact AssessmentFuture Business Impact Assessment

Page 24: GlaxoSmithKline vs Pfizer UBI Business & Competitive Intelligence Presentation by : Aksenov Yuri Pascal Andrea Hendricx Chris Brussels, December 15th 2006

In the near future, risks for pharma seem higher than the In the near future, risks for pharma seem higher than the opportunities.opportunities.

The best equiped to face the new challenges will win.The best equiped to face the new challenges will win.

Summary

Future Business Impact AssessmentFuture Business Impact Assessment

Page 25: GlaxoSmithKline vs Pfizer UBI Business & Competitive Intelligence Presentation by : Aksenov Yuri Pascal Andrea Hendricx Chris Brussels, December 15th 2006

PfizerPfizer : 1 : 1stst Recommendation Recommendation

RecommendationsRecommendations

Pfizer Pfizer

Big companyBig company

Loose piecesLoose pieces

No course of actionNo course of action

Align the businessAlign the business

Get smaller andGet smaller and

align the businessalign the business

Be clear :Be clear :

VisionVision

MissionMission

StrategyStrategy

Be manageableBe manageable

Page 26: GlaxoSmithKline vs Pfizer UBI Business & Competitive Intelligence Presentation by : Aksenov Yuri Pascal Andrea Hendricx Chris Brussels, December 15th 2006

PfizerPfizer : 2 : 2ndnd recommendation recommendation

RecommendationsRecommendations

Co-marketing with generic drug manufacturersCo-marketing with generic drug manufacturers

Page 27: GlaxoSmithKline vs Pfizer UBI Business & Competitive Intelligence Presentation by : Aksenov Yuri Pascal Andrea Hendricx Chris Brussels, December 15th 2006

PfizerPfizer : 3 : 3rdrd recommendation recommendation

RecommendationsRecommendations

Go on-line e-businessGo on-line e-business

Pharmacy

Wholesaler

Page 28: GlaxoSmithKline vs Pfizer UBI Business & Competitive Intelligence Presentation by : Aksenov Yuri Pascal Andrea Hendricx Chris Brussels, December 15th 2006

PfizerPfizer : 4 : 4thth recommendation recommendation

RecommendationsRecommendations

Promotion : Brand or efficacy of productPromotion : Brand or efficacy of product

Page 29: GlaxoSmithKline vs Pfizer UBI Business & Competitive Intelligence Presentation by : Aksenov Yuri Pascal Andrea Hendricx Chris Brussels, December 15th 2006

Pfizer : 5Pfizer : 5thth recommendation recommendation

RecommendationsRecommendations

Research & Development : Better focusResearch & Development : Better focus

Improve OTC portfolioImprove OTC portfolio Avoid entering areas where excellence is reachedAvoid entering areas where excellence is reached

Page 30: GlaxoSmithKline vs Pfizer UBI Business & Competitive Intelligence Presentation by : Aksenov Yuri Pascal Andrea Hendricx Chris Brussels, December 15th 2006

Glaxosmithkline : 1Glaxosmithkline : 1stst Recommendation Recommendation

RecommendationsRecommendations

Research & Development : CONTINUEResearch & Development : CONTINUE

Page 31: GlaxoSmithKline vs Pfizer UBI Business & Competitive Intelligence Presentation by : Aksenov Yuri Pascal Andrea Hendricx Chris Brussels, December 15th 2006

Glaxosmithkline : 2Glaxosmithkline : 2ndnd recommendation recommendation

RecommendationsRecommendations

VaccinationVaccination

Continu effortsContinu efforts

Page 32: GlaxoSmithKline vs Pfizer UBI Business & Competitive Intelligence Presentation by : Aksenov Yuri Pascal Andrea Hendricx Chris Brussels, December 15th 2006

Glaxosmithkline : 3Glaxosmithkline : 3rdrd recommendation recommendation

RecommendationsRecommendations

Go for preventionGo for prevention

Less sofisticated Less sofisticated drugs needed.drugs needed.

Competition ?Competition ?

Page 33: GlaxoSmithKline vs Pfizer UBI Business & Competitive Intelligence Presentation by : Aksenov Yuri Pascal Andrea Hendricx Chris Brussels, December 15th 2006

Glaxosmithkline : 4Glaxosmithkline : 4thth recommendation recommendation

RecommendationsRecommendations

Focus on neglected diseasesFocus on neglected diseases

HIV/AIDSHIV/AIDS

TuberculosisTuberculosis

MalariaMalaria

Obesitas – CholesterolObesitas – Cholesterol

etc …etc …

Enhance participation in Enhance participation in community programmescommunity programmes

Animal testingAnimal testing

Human testingHuman testing

Image buildingImage building

PRPR

Page 34: GlaxoSmithKline vs Pfizer UBI Business & Competitive Intelligence Presentation by : Aksenov Yuri Pascal Andrea Hendricx Chris Brussels, December 15th 2006

Glaxosmithkline : 5Glaxosmithkline : 5thth recommendation recommendation

RecommendationsRecommendations

Acquisition OTCAcquisition OTC

Candidate good prospect for product diversificationCandidate good prospect for product diversification

Page 35: GlaxoSmithKline vs Pfizer UBI Business & Competitive Intelligence Presentation by : Aksenov Yuri Pascal Andrea Hendricx Chris Brussels, December 15th 2006

General for the pharmaceutical marketGeneral for the pharmaceutical market

OpportunitiesOpportunities

Entering new markets : China, East-Europe, Latin-America, VietnamEntering new markets : China, East-Europe, Latin-America, Vietnam

Alliance with BioTech companies : Technology, innovationAlliance with BioTech companies : Technology, innovation

Page 36: GlaxoSmithKline vs Pfizer UBI Business & Competitive Intelligence Presentation by : Aksenov Yuri Pascal Andrea Hendricx Chris Brussels, December 15th 2006

Distinguishing marketsDistinguishing markets

ConclusionConclusion

Future key players:Future key players:

Generics manufacturersGenerics manufacturersFuture Key Players:Future Key Players:

Pharma innovatorsPharma innovators

““Cure” marketCure” market ““Prevent” marketPrevent” market

Page 37: GlaxoSmithKline vs Pfizer UBI Business & Competitive Intelligence Presentation by : Aksenov Yuri Pascal Andrea Hendricx Chris Brussels, December 15th 2006

Distinguishing marketsDistinguishing markets

ConclusionConclusion

pastpast presentpresent futurefuture

CureCure

R&

D

R&

D

Focu

sFo

cus

PreventPrevent

Sale

s Sale

s Fo

cus

Focu

s

Page 38: GlaxoSmithKline vs Pfizer UBI Business & Competitive Intelligence Presentation by : Aksenov Yuri Pascal Andrea Hendricx Chris Brussels, December 15th 2006

QuestionsQuestions

Page 39: GlaxoSmithKline vs Pfizer UBI Business & Competitive Intelligence Presentation by : Aksenov Yuri Pascal Andrea Hendricx Chris Brussels, December 15th 2006

Secondary sourcesSecondary sources

Annual report Pfizer 2005Annual report Pfizer 2005

Annual report GSK 2006Annual report GSK 2006

IMS Health Global IMS Health Global PhPhaarrma forecama forecasst Feb. 2006t Feb. 2006

NYSE, sept.2006NYSE, sept.2006

MIDAS, new market segmentation Feature Dec. 2005MIDAS, new market segmentation Feature Dec. 2005

Neil Mahoney - Neil Mahoney - Global Business Management ConceptsGlobal Business Management Concepts,, presentationpresentation

PharmaBiz, "Struggle of the giants",  May. 2006 PharmaBiz, "Struggle of the giants",  May. 2006

Wood McKenzieWood McKenzie

www.imshealth.com

www.pharmaexec.com

www.chartsbank.com

BCG e-Health ReportsBCG e-Health Reports

Wall Street JournalWall Street Journal