gilut infeksi virus herpes simplex.pptx

8/10/2019 Gilut Infeksi Virus Herpes Simplex.pptx

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D R G . Z A I V I A N I J U N I A N I K , M K E S

Infeksi Virus Herpes Simplex


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DefinisiHerpes simpleks virus ( HSV ) is the most commen

viral infectious in oral mucosa with , sore mouth,

and painful


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Etiologi

Virus Herpes tye 1 dan tipe 2 ( un common)


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Klasifikasi

Primary acute herpetic gingivostomatitis

children and young adult

Herpetiformis Sekunder ( Herpetic Stomatitis,herpes labiasis)young adult

Immunocompromised conditions recurent


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Clinical Features

Primary Herpetic gingivostomatitis

Prodromal symptoms : high fever,

headache, sore mouth, and painfulcervical lymphadenopathy

Lesions : singel or multiple, smallvasiclesthat leave round rupture. Shallow coalescing

ulcers Location : gingiva, Tongue, lips, palate , and

Buccal mucosa ( Non keratine layer)

Duration : 6-10 days


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Secodary Herpetic Stomatitis

Prodromal symptoms : noconstitutional symptoms

Lesions : smaller and fewerlesions Locations : Hard Palateand

attached gingiva.

Pharyngotonsillar

Duration : 6-10 days


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Histopathology


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Herpes Labialis

Prodromal Symptoms : Burning, Itching, andmild pain around the affected area

Lesions : small clustering vesicles that

rupture leaven ulcers that crust Location :Vermillion borderof the lip and

perioral skin

Duration : 5 - 8 days


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Diagnosis

The diagnosis is based on theclinical presentation.

The definitive criterion fordiagnosing a herpetic infection isisolation of the virus in tissue

culture Sitology : inoculated with thevesicular fluid ( Titer AR )

TZank


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Differential Diagnosis

Aphotus Ulcers Herpangina

Hand, Food, and mouthdisease

Acute Necrotizingulcerative gingivitis

Pemphigoid

Erythema multiforme

Pemphigus Streptoccal stomatitis

Gonococcal stomatitis

Primary and secondary

syphilis

Traumatic Lesions


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Basic Guidelines : Treatment

Systematic antiviral treatmentis employe if thepatients is immunocompromised or as aprophylactic regimen in patients who have

frequent recurrences due to known trigger factor. Patients should stay inbed for 4-6 days in case

of primary herpetic gingivostomatitis

Avoiding of spicy and hard foods and tooth

brushing during acute stage is recommended


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Topical Treatment

Primary herpes Gingivostomatitis: Mouth georgletopical with 0,5 or 1% liposom hidroklorida for

temporary treatmentHerpes labialis: 5% acyclovir creamin carrierliposom use for prodromal phase1,8% Tetrakain cream6x/day


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gilut infeksi virus herpes simplex.pptx

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