fusion 1 day presentation
DESCRIPTION
FUSION 1 Day Contact Lenses combining HA + TSP for the ultimate Eye comfort.TRANSCRIPT
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The contact lens that The contact lens that thinks its an eye dropthinks its an eye drop
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Contact Lens Related Dry Contact Lens Related Dry EyeEye
55% of wearers experience end-of-day discomfortMost common cause of drop-out is
due to discomfort41% due to dryness symptoms
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FUSION CONCEPTThe new generation of contact lenses that release a natural tear substitute
Safilens has dedicated years of research and innovation looking for ways to maximise contact lens comfort and optimise ocular hydration. Safilens believes the controlled release of bio-active substances during contact lens wear to be the key to maintaining the delicate relationship between the contact lens and the tear film
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Hyaluronic AcidHyaluronic AcidBenefits in EyecareBenefits in Eyecare
Biological polymerHA’s function in nature
is to attract waterextremely effective, even at very low concentrationsAttracts 3000x its own weight in water
Bio-adhesive propertiesNon Newtonian
behaviourProtective effect on
corneal epithelium
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Tamarind Seed Tamarind Seed Polysaccharide (TSP)Polysaccharide (TSP)
Similar structure to ocular mucin
Similar structure to ocular mucin
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HA + TSPHA + TSPThe interaction between HA and TSP is
cooperative forming a new bi-polymer
Resulting performance > SUM of its 2 partsResulting performance > SUM of its 2 parts
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Relative Performance of Relative Performance of tear substitutestear substitutes
Natural Semi-synthetic Synthetic
HA TSP HPMC CMC PVA PVP
Hydration **** **** ** **** **** *
Lubrication
**** **** ** *** *** ***
Muco-adhesive
**** **** * **** * *
Muco-mimetic
**** **** * * * *
Viscoelastic
**** **** * *** * *
Wound healing
*** *** * ** * *
Ref: Current Medical Research and Opinion (2006)
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Non Newtonian Fluid at High Viscosity Non Newtonian Fluid at Low Viscosity
Non-Newtonian BehaviourNon-Newtonian Behaviour
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How it works…How it works…
Polymer chains become more disorganised with heating increasing its fluiditySheer force from blinking aids flow into
tearsNon-Newtonian behaviour mimics the
natural tearsMore fluid during blink – more viscous between blinks
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Fusion Technolog
y
Increased tear film stability for
improved comfort
Prolonged muco-
mimetic activity
Maintains lens
hydration longer
Constant hydration
and lubrication
for excellent VA
Minimal friction
between lens and lid
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Ultra-thin lens designHandles wellLens can be pulled quite robustly without breaking
Excellent DK/t: 40 (-3.00 at 35ºC)
More or less same as other hydrogel daily disposables
Lens design Lens design
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ParametersParameters
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-0.50 to -6.00 (0.25 steps)
-6.50 to -12.00 (0.50 steps)
Filcon IVIncorporating a bipolymer of HA-TSP
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At the end of the day, At the end of the day, which would you choose?which would you choose?