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FINAL PROGRAM

April 4-5, 2019HILTON CHICAGO MAGNIFICENT MILE SUITES CHICAGO, IL

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Midwest Clinical& TranslationalResearch Meetingof Central Society for Clinical& Translational Research andMidwestern American Federationfor Medical Research

Midwest Clinical and Translational Research Meeting

of Central Society for Clinical and Translational Research and Midwestern American Federation for Medical Research

April 2-3, 2020 • Chicago, ILADA Conference & Meeting Center

www.csctr.org

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FINAL PROGRAM • APRIL 4-5, 2019 Midwest Clinical & Translational Research Meeting of CSCTR and MWAFMR 1

Central Society for Clinical and Translational Research

555 East Wells StreetSuite 1100Milwaukee, WI 53202Phone (414) 273-2209Fax (414) [email protected]

Kim Schardin, MBA, CAE Executive Director

Midwestern Section American Federation for Medical Research

500 Cummings Center, Ste 4400 Beverly, MA 01915 Phone (978) 927-8330 Fax (978) [email protected]

Elissa KleinExecutive Director

TABLE OF CONTENTS

Welcome ......................................................................................................................... 2Midwest Clinical and Translational Research Meeting ............................................ 3

Registration Desk Hours 3Annual Business Meeting 3Poster Sessions 3Learning Objectives 3CME Certificate 3

Learner Notification ...................................................................................................... 4About 5CSCTR Council 5CSCTR Past Presidents 5

AFMR Information ....................................................................................................... 6About the American Federation for Medical Research (AFMR) 6AFMR Past Presidents 6AFMR Midwestern Section Council 6

Special Acknowledgement ........................................................................................... 7Abstract Reviewers 7

Award Winners .............................................................................................................. 8Getting Around ............................................................................................................. 9

Hilton Floor Plan 9Poster Hall 10

Schedule-at-a-Glance .................................................................................................. 11Meeting Schedule ........................................................................................................ 12Featured Presenters ..................................................................................................... 15

MWAFMR Career Development Workshop 15Cardiology/Pulmonary Lecture 15Max Miller Lecture in Diabetes Research 15AFMR Keynote 16Department Chair Session I 16Department Chair Session II 17John B. Hickam Endowed Lecturer 18Research Innovations 18

ABSTRACT POSTER TITLES & AUTHORS ......................................................... 21Poster Session A 21Poster Session B 26Poster Session C 30

Author Index ................................................................................................................ 34

Midwest Clinical and Translational Research Meeting

of Central Society for Clinical and Translational Research and Midwestern American Federation for Medical Research

April 2-3, 2020 • Chicago, ILADA Conference & Meeting Center

www.csctr.org

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2 Midwest Clinical & Translational Research Meeting of CSCTR and MWAFMR FINAL PROGRAM • APRIL 4-5, 2019

WELCOME TO THE 2019 COMBINED ANNUAL MEETING

I hope you have been looking forward to this meeting, to learn from the most prestigious leaders in our fields and to collaborate with one another. We have a terrific program planned, including outstanding invited speakers, our traditional Department Chair sessions highlighting early career faculty at two Midwest medical schools (University of Michigan and Loyola University), “hot” new science from members and trainees presented as posters and oral sessions, and multiple mentoring opportunities. My sincere hope is that you take much good away from this meeting, which will resonate long after in your career.

CSCR (as it was then known) held its first meeting 91 years ago, in November 1928, and in October 1969 the first joint meeting of CSCTR and MWAFMR convened, making this our 51st meeting!

To start the next half century, we updated the name to “Midwest Clinical and Translational Research Meeting of CSCTR and MWAFMR.” Throughout this long history, our meeting has accomplished its mission to share research techniques and new findings, learn the latest on the management of diseases and disorders across various subspecialties of medicine, and provide career and personal development activities for early career investigators.

I extend my sincere gratitude to the Program Committee for creating an outstanding program.

Special thanks to the many reviewers required to score the numerous abstracts. Their titles are listed on page 6.

I encourage you to continue your involvement in CSCTR and/or AFMR. Check out our websites for membership information.

Timothy B. Niewold, MD CSCTR President

AFMR WELCOMEAs Chair of the Midwestern Section of the AFMR (MWAFMR), I welcome you to Chicago and the Midwest Clinical and Translational Research Meeting of CSCTR and MWAFMR. The strength of this program lies in the multidisciplinary educational offerings and collegial setting. The goal of the AFMR is to develop and mentor tomorrow’s leaders in medical research, through providing a venue to share and present research, recognize outstanding achievements in research, meet new peers and mentors, gain valuable career advice, and become involved with society service. On Thursday afternoon, during the Career Development Workshop, Dr. Dawn Davis will speak on career development grant writing and Dr. Joumana Chaiban will speak about challenges and opportunities for immigrant physician scientists. Friday morning we have an outstanding AFMR Keynote Speaker, Dr. Bradley Britigan from the University of Nebraska Medical Center. We thank you for attending! Come up and introduce yourself during the meeting and ask me how to get more involved in AFMR!

Vijay Shivaswamy, MBBS, MS Chair, AFMR Midwestern Section Council

WELCOME


MIDWEST CLINICAL AND TRANSLATIONAL RESEARCH MEETING OF CSCTR AND MWAFMR

Registration Desk HoursThursday: 8:30 am – 7:00 pmFriday: 6:30 am – 3:30 pm

Annual Business MeetingThe CSCTR Annual Business Meeting is scheduled for Friday at 9:15 am and is open to all attendees.

Poster Sessions2019 will continue the tradition of hosting three poster display sessions:

Thursday, April 4th

Session A: 5:00 – 6:30 pm and held in conjunction with the Opening Reception

Friday, April 5th

Session B: 11:30 am – 1:00 pm and held in conjunction with the Lunch Break

Session C: 4:30 – 6:00 pm and held in conjunction with the Closing Reception

Learning ObjectivesThe 2019 Midwest Clinical and Translational Research Meeting of CSCTR and MWAFMR presents the Hickam Lecture, Keynote Speaker, plenary sessions, and Oral Abstract sessions on topics of timely interest for researchers and physicians interested in the broad field of clinical research.

Participants of the 2019 Meeting will acquire knowledge into clinical research techniques and new findings in various aspects of internal medicine and other fields.

At the completion of the meeting, participants should be able to: • Recognize the value of new research techniques• Describe new research findings in cardiology,

gastroenterology, pulmonary and critical care, hematology, oncology, nephrology, infectious disease, allergy, immunology, and rheumatology

• Explain the diagnosis and management of diseases and disorders across various subspecialties of medicine

CME CertificateSatisfactory completion Learners must complete an evaluation form to receive a certificate of completion. Your chosen sessions must be attended in their entirety. Partial credit of individual sessions is not available. If you are seeking continuing education credit for a specialty not listed below, it is your responsibility to contact your licensing/certification board to determine course eligibility for your licensing/certification requirement.

Physicians

Accreditation Statement: In support of improving patient care, this activity has been planned and implemented by Amedco LLC and the Central Society for Clinical and Translational Research. Amedco LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

Credit Designation Statement: Amedco LLC designates this live activity for a maximum of 12 AMA PRA Category 1 CreditsTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Abstracts in Journal of Investigative MedicineAbstracts from the meeting will be available online in the Journal of Investigative Medicine as of May 27, 2019. Go to afmr.org/journal.cgi for access. The hard copy will be mailed to meeting attendees in June. If you presented an abstract, the citation should be: J Investig Med 2019;67:(page numbers).

MIDWEST CLINICAL AND TRANSLATIONAL RESEARCH MEETING


LEARNER NOTIFICATION

Midwest Clinical and Translational Research Meeting of CSCTR and MWAFMRApril 4 - 5, 2019 • Chicago, IL

Acknowledgement of Financial Commercial SupportNo financial commercial support was received for this educational activity.

Acknowledgement of In-Kind Commercial SupportNo in-kind commercial support was received for this educational activity.

Satisfactory Completion Learners must complete an evaluation form to receive a certificate of completion. Your chosen sessions must be attended in their entirety. Partial credit of individual sessions is not available. If you are seeking continuing education credit for a specialty not listed below, it is your responsibility to contact your licensing/certification board to determine course eligibility for your licensing/certification requirement.

Physicians In support of improving patient care, this activity has been planned and implemented by Amedco LLC and the Central Society for Clinical and Translational Research. Amedco LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

Credit Designation Statement – Amedco LLC designates this live activity for a maximum of 12 AMA PRA Category 1 CreditsTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Objectives - After attending this program you should be able to: 1. Recognize the value of new research techniques2. Describe new research findings in cardiology,

gastroenterology, pulmonary, hematology, oncology, nephrology, infectious disease, allergy, immunology, rheumatology

3. Explain the diagnosis and management of diseases/disorders across various subspecialties of medicine

Disclosure of Conflict of InterestThe following table of disclosure information is provided to learners and contains the relevant financial relationships that each individual in a position to control the content disclosed to Amedco. All of these relationships were treated as a conflict of interest, and have been resolved. (C7 SCS 6.1- ‐6.2, 6.5)

All individuals in a position to control the content of CE are listed in the program book. If their name is not listed below, they disclosed that they had no relevant financial relationships.

How to get your certificate:1. Go to http://csctr.cmecertificateonline.com2. Click on the “51st Annual Combined Meeting of CSCTR and MWAFMR” link 3. Evaluate the meeting

FIRST NAME LAST NAME COMMERCIAL INTEREST:RELATIONSHIP

Vineet Arora UpToDate:Other,McGraw Hill:Other,ABIM:Scientific/Medical Advisory Board MemberMatthew Churpek Patent pending for risk stratification algorithms:Patent Holder,Research funding from EarlySense:OtherJohn Dickinson Gilead Sciences:Scientific/Medical Advisory Board MemberAriel Feldstein Jecure Therapeutics:OtherDavid Kennedy EMD Millipore:Patent HolderDudley Lamming Delos Pharmaceuticals:Scientific/Medical Advisory Board Member,Delos

Pharmaceuticals:Consultant,Davita Clinical Research:EmployeeSuthat Liangpunsakul Durect Coporation:ConsultantEmil Lou Minnetronix:Scientific/Medical Advisory Board Member, Novocure:Consultant,Nomocan:ConsultantRupal Mehta Abbott:Stock Shareholder,Abvie Pharmaceuticals:Stock Shareholder,Teva Pharmaceuticals:Stock

ShareholderTimothy Niewold EMD Serono, Microdrop, and Janssen, Inc:Research Grant Site Principal InvestigatorSharmilee Nyenhuis Sanofi:Scientific/Medical Advisory Board MemberJason Rose Globin Solutions, Inc.:Corporate Board Member,Globin Solutions, Inc.:Stock Shareholder,Globin

Solutions, Inc.:Employee,Globin Solutions, Inc.:Other,Globin Solutions, Inc.:Patent Holder,CO poisoning antidote:Patent Holder

Milda Saunders Help Comet, Inc.:OtherVijay Shivaswamy KOWA:Research Grant Site Principal Investigator,Novo Nordisk:Research Grant Site Principal InvestigatorGregory Vercellotti CSL Behring:Research Grant Overall Principal Investigator,Astellas:Research Grant Overall Principal

InvestigatorLorraine Ware CSL Behring:Consultant

Please print all pages of your certificate for your record. Questions? Email [email protected]


CSCTR CouncilPresident Timothy B. Niewold, MD New York, NY

President-Elect Terry G. Unterman, MD Chicago, IL

Vice President Dawn Belt Davis, MD, PhD Madison, WI

Secretary-Treasurer Debra Romberger, MD Omaha, NE

Past President Abraham Thomas, MD, MPH Springfield, MA

Editor Jeffrey Laurence, MD Greenwich, CT

Councilors Vineet M. Arora, MD, MAPP Chicago, IL

Rachel Caskey, MD, MAPP Chicago, IL

Steven Dudek, MD Chicago, IL

Suthat Liangpunsakul, MD, MPH Westfield, IN

Mohammad N. Uddin, PhD, FAHA Georgetown, TX

Gregory M. Vercellotti, MD, FACP Minneapolis, MN

CSCTR INFORMATION

About the Central Society for Clinical and Translational Research (CSCTR)The Central Society for Clinical and Translational Research is one of the oldest academic medical societies in the Midwest.

Our Vision: Promoting a vibrant, supportive community of multidisciplinary, clinical, and translational medical research to benefit humanity.

Our Mission: Develop and support communication, collaboration, and career development within a community of medical researchers in the central U.S. and beyond.

Members are academic leaders of medical schools in the Midwest however, CSCTR has active members throughout the U.S. and Canada. The society publishes the monthly Translational Research: The Journal of Laboratory and Clinical Medicine and holds an Annual Meeting that contains cutting-edge papers, posters, lectures, and state-of-the-art forums. You are encouraged to apply for membership.

CSCTR Past Presidents1928 – Frank Billings, MD1929 – Frank Billings, MD1930 – Lee Foshay, MD1931 – Louis Leiter, MD1932 – A. M. Snell, MD1933 – M. A. Blankenhorn, MD1934 – W. S. Middleton, MD1935 – Cyrus C. Sturgis, MD1936 – Fred M. Smith, MD1937 – David P. Barr, MD1938 – William H. Bunn, MD1939 – Walter H. Nadler, MD1940 – Charles A. Doan, MD1941 – Lawrence D. Thompson, MD1942 – Arlie R. Barnes, MD1943 – John Walker Moore, MD1944 – Cecil J. Watson, MD1945 – Willis M. Fowler, MD1946 – Roy W. Scott, MD1947 – Carl V. Moore, MD1948 – Richard McKean, MD1949 – E. V. Allen, MD1950 – Wesley Spink, MD1951 – William Bean, MD1952 – Barry Wood, MD1953 – George E. Burch, MD1954 – Jerome Conn, MD1955 – Clayton G. Loosli, MD1956 – Randall Sprague, MD1957 – Kenneth Kohlstaedt, MD1958 – Thornton Scott, MD1959 – Edgar S. Gordon, MD1960 – John H. Dingle, MD1961 – Gordon Meiklejohn, MD1962 – Charles Rammelkamp, MD1963 – Donald Seldin, MD1964 – Richard Ebert, MD1965 – David Earle, MD1966 – Robert A. Good, MD1967 – Austin S. Weisberger, MD1968 – James F. Hammarsten, MD1969 – William H. Daughaday, MD1970 – John B. Hickam, MD1971 – Oscar D. Ratnoff, MD1972 – Leonard L. Madison, MD1973 – Robert F. Schilling, MD

1974 – John W. Eckstein, MD1975 – Gene H. Stollerman, MD1976 – Fred Allison, MD1977 – Giles G. Bole, Jr., MD1978 – David Kipnis, MD1979 – Roy Patterson, MD1980 – Norton Greenberger, MD1981 – Walter J. Daly, MD1982 – Arnold Weissler, MD1983 – Virginia Donaldson, MD1984 – Gilbert M. Schiff, MD1985 – Thomas F. Ferris, MD1986 – Francois M. Abboud, MD1987 – William N. Kelley, MD1988 – Patrick J. Mulrow, MD1989 – Arthur Rubenstein, MD1990 – August M. Watanbe, MD1991 – Theodore A. Kotchen, MD1992 – Adel A.F. Mahmoud, MD1993 – Murray L. Levin, MD1994 – Robert G. Luke, MD1995 – Tadataka Yamada, MD1996 – Karl Weber, MD1997 – John Phair, MD1998 – Gary W. Hunninghake, MD1999 – Daniel Villareal, MD2000 – D. Craig Brater, MD2001 – H. David Humes, MD2002 – Robert F. Todd, III, MD PhD2003 – Jeffrey Glassroth, MD‘03/’04 – Joe G.N. Garcia, MD (6 – mos term)2004 – Lawrence A. Frohman, MD2005 – Rose S. Fife, MD2006 – David W. Kamp, MD2007 – James Martins, MD2008 – Brian Hoit, MD2009 – David Crabb, MD2010 – Bradley Britigan, MD2011 – Virginia J. Savin, MD2012 – Neal Weintraub, MD2013 – Jordan P. Metcalf, MD2014 – Roy E. Weiss, MD, PhD2015 – Ellen McCarthy, MD2016 – Roy L. Silverstein, MD2017 – Abraham Thomas, MD, MPH

About


AFMR INFORMATION

AFMR Midwestern Section CouncilChair Vijay Shivaswamy, MBBS, MS Omaha, NE

Chair-Elect Joumana T. Chaiban, MD, FACE Chicago, IL

Past Chair Dawn B. Davis, MD, PhD Madison, WI

Secretary-Treasurer Attaya Suvannasankha, MD Indianapolis, IN

Councilors Jennifer Alexander-Brett, MD, PhD Saint Louis, MO

Venkata Andukuri, MD, MPH Omaha, NE

J. Brian Byrd, MD, MS, FAHA, FACC Ann Arbor, MI

John Dickinson, MD, PhD Omaha, NE

Joshua Englert, MD Columbus, OH

Jacquelyn P. Kulinski, MD Milwaukee, WI

Edgar Lerma, MD Berwyn, IL

Alaleh Mazhari, DO, FACE Maywood, IL

Rupal C. Mehta, MD Chicago, IL

Sriram Ramaswamy, MD Omaha, NE

Amy Shah, MD, MS Cincinnati, OH

Yutong Zhao, MD, PhD Columbus, OH

About the American Federation for Medical Research (AFMR)The mission of the American Federation for Medical Research is to “develop and mentor tomorrow’s leaders in medical research.” The AFMR follows this mission with the goal to:

• Foster excellence in training and successful development of medical investigators• Disseminate scholarly, multidisciplinary, ethical research on human disease and health care delivery• Educate public and government leaders about medical research and the importance of its support

The AFMR’s diverse membership positions the organization as one of the few medical associations with a broad constituency. Members enjoy the ability to tap into a professional network of colleagues whose interests and expertise facilitate the “cross fertilization” of information about current issues in biomedical research. The AFMR repeatedly demonstrates how clinical and basic research efforts integrate to provide the scientific basis for medical practice. The organization’s translational aspect has broad reaching clinical applications and strengthens the fields of scientific study across multiple medical disciplines.

AFMR Past Presidents1960 – William W. Stead, MD1961 – Arnold Relman, MD1962 – Richard Hill, Jr., MD1963 – George E. Schreiner, MD1964 – Alfred J. Bollet, MD1965 – Morton Bogdanoff, MD 1966 – Richard Havel, MD 1967 – William Huckabe, MD1968 – Henry N. Wagner Jr., MD 1969 – Edgar J. Sanford, MD 1971 – Francois M. Abboud, MD 1972 – Michael Bell, MD1973 – Kenneth L. Melmon, MD 1974 – Robert A. Kreisberg, MD 1975 – David R. Challoner, MD 1976 – Robert Zelis, MD1977 – Samuel Thayer, MD 1978 – Gerald F. DiBona, MD 1979 – William N. Kelley, MD 1980 – Anthony S. Fauci, MD 1981 – Suzanne Oparil, MD 1982 – Jerrold M. Olefsky, MD1983 – Bernadine H. Bulkley, MD 1984 – Benjamin D. Schwartz, MD 1985 – Edwin C. Cadman, MD 1986 – Gary Hunninghake, MD 1987 – David Hathaway, MD1988 – Pamela B. Davis, MD1989 – Willa Hsueh, MD 1990 – Richard A. Cohen, MD

1991 – J. Sanford Schwartz, MD 1992 – Andrew R. Hoffman, MD 1993 – Jonathan Weissler, MD 1994 – Roy L. Silverstein, MD1995 – Veronica M. Catanese, MD, MBA 1996 – Bradley E. Britigan, MD1997 – Jeffrey A. Kern, MD 1998 – Monica M. Farley, MD 1999 – William L. Lowe, Jr, MD 2000 – Charles W. Flexner, MD 2001 – Kevin D. O’Brien, MD 2002 – Jane E. B. Reusch, MD 2003 – Errol D. Crook, MD 2004 – Mark R. Burge, MD2005 – Deborah Zucker, MD, PhD 2006 – Jonathan Q. Purnell, MD 2007 – Jim C. Oates, MD2008 – Alan L. Buchman, MD 2009 – Abdulla K Salahudeen, MD 2010 – Francis J. Miller, MD2011 – Sharma S. Prabhakar, MD, MBA 2012 – Abraham Thomas, MD, MPH 2013 – Robert J. Freishtat, MD, MPH 2014 – MingMing Ning, MD, MMSc 2015 – Amir A. Zeki, MD, MAS2016 – Arman Krikorian, MD, FACE2017 – Florence Rothenberg, MS, MD, FACC2018 – Suthat Liangpunsakul, MD, MPH


SPECIAL ACKNOWLEDGEMENT

Abstract ReviewersSaira Ajmal, MDAdvocate Health CareOak Lawn, IL

Jennifer Alexxander-Brett, MD, PhDWashington University, School of MedicineSt. Louis, MO

Amy C. Arnold, PhDPennsylvania State UniversityHershey, PA

Patrick G. Belvitch, MDUniversity of Illinois at ChicagoChicago, IL

Rachel Caskey, MD, MAPPUniversity of Illinois at ChicagoChicago, IL

Kelly Cawcutt, MD, MS, FACPUniversity of Nebraska Medical CenterOmaha, NE

Joumana T. Chaiban, MD, FACEUIC/Advocate Christ Medical CenterChicago, IL

James Cook, MDLoyola UniversityChicago, IL

John D. Dickinson, MD, PhDUniversity of Nebraska Medical CenterOmaha, NE

Prabhatchandra Dube, PhDUniversity of ToledoToledo, OH

Steven Dudek, MDUniversity Illinois at ChicagoChicago, IL

Joshua A. Englert, MDThe Ohio State UniversityColumbus, OH

Dustin Fraidenburg, MDUniversity of Illinois at ChicagoChicago, IL

Robert D. Guzy, MD, PhDThe University of ChicagoChicago, IL

Steven T. Haller, PhDUniversity of Toledo College of Medicine and Life SciencesToledo, OH

Silesh Harwani, MD, PhDUniversity of Iowa Carver College of MedicineIowa City, IA

Pinelopi Kapitsinou, MDUniversity of Kansas Medical CenterKansas City, KS

David J. Kennedy, PhDThe University of ToledoToledo, OH

Rami N. Khoriaty, MDUniversity of MichiganAnn Arbor, MI

Sivarajan Kumarasamy, PhDUniversity of ToledoToledo, OH

Terrence T. Kummer, MD, PhDWashington University, School of MedicineSt. Louis, MO

Dudley W. Lamming, PhDUniversity of Wisconsin – MadisonMadison, WI

Jeffrey Laurence, MDWeill Cornell Medical CollegeGreenwich, CT

Suthat Liangpunsakul, MD, MPHIndiana University School of MedicineWestfield, IN

Jennie Lin, MD, MTRNorthwestern UniversityChicago, IL

Emil Lou, MD, PhD, FACPUniversity of MinnesotaMinneapolis, MN

Sidharth Mahapatra, MD, PhDUniversity of Nebraska Medical CenterOmaha, NE

Alaleh Mazhari, DOLoyola University Medical CenterChicago, IL

Rupal C. Mehta, MDNorthwestern UniversityChicago, IL

Jonathan Miner, MD, PhDWashington University, School of MedicineSt. Louis, MO

Rochelle N. Naylor, MDUniversity of ChicagoChicago, IL

Timothy B. Niewold, MDNew York UniversityNew York, NY

Sharmilee M. Nyenhuis, MDUniversity of Illinois ChicagoChicago, IL

Brian T. O’Neill, MD, PhDUniversity of Iowa Carver College of MedicineIowa City, IA

Julie H. Ostrander, PhDUniversity of MinnesotaMinneapolis, MN

Micah Prochaska, MDUniversity of ChicagoChicago, IL

Sriram Ramaswamy, MDVA Nebraska – Western Iowa Healthcare SystemOmaha, NE

Jason J. Rose MD, MBAUniversity of PittsburghPittsburgh, PA

Florence Rothenberg, MS, MD, FACCUniversity of CincinnatiCincinnati, OH

Jose B. Saenz, MD, PhDWashington University, School of MedicineClayton, MO

Milda R. Saunders, MD, MPHUniversity of Chicago,Chicago, IL

Amy Sanghavi Shah, MD, MSCincinnati Children’s Medical CenterCincinnati, OH

Chetan Shenoy, MBBSUniversity of MinnesotaPlymouth, MN

Vijay Shivaswamy, MBBS, MSUniversity of Nebraska Medical CenterOmaha, NE

Emily K. Sims, MDIndiana University School of MedicineCarmel, IN

Attaya Suvannasankha, MDIndiana University School of MedicineIndianapolis, IN

Tuan Tran, MD, PhDIndiana University School of MedicineIndianapolis, IN

Mohammad N. Uddin, PhD, FAHAOrion Institute for Translational MedicineGeorgetown, TX

Gregory M. Vercellotti, MD, FACPUniversity of MinnesotaMinneapolis, MN

Theresa Wampler Muskardin, MDNYU Langone Medical CenterNew York, NY

Are you interested in reviewing abstracts for the 2020 Annual Meeting? Send an email to [email protected] with your name, institution, specialty, and email address.


Congratulations to all recipients.

Outstanding Young InvestigatorHongxia Ren, PhD – Indiana University

AFMR Henry ChristianShana Kothari – University of Illinois at ChicagoJuan C. Rojas – University of Chicago

K AwardPatrick Belvitch – University of Illinois at ChicagoJose Cordoba-Chacon – University of Illinois at ChicagoLuke Engelking – UT SouthwesternDustin R. Fraidenburg – University of Illinois at ChicagoMichael Pulia – University of Wisconsin – MadisonSantosh Saraf – University of Illinois at ChicagoChetan Shenoy – University of Minnesota

Midwest TraineeAbdullahi Abdi – Northwestern University Feinberg School of MedicineYing Wang – University of Minnesota Norelle C. Wildburger – Washington University in St. LouisDeyang Yu – University of Wisconsin – Madison

Oral AbstractSamia Asif, MD – University of Missouri – Kansas CityWeiguo Chen, MD, PhD – University of Illinois at ChicagoYulia Epshtein, PhD – University of Illinois at ChicagoJulien Feghaly, MD – St. Louis University HospitalWenjing Feng, MD – Qingdao UniversityBong Sook Jhun, PhD – University of MinnesotaFatimah K. Khalaf, MB ChB – University of ToledoMaximilian McCann, BS – University of Illinois at ChicagoJaspreet S. Suri, MD – Beth Israel Deaconess Medical CenterPratik S. Velangi, MD – University of MinnesotaNajia Waheed, MBBS – Rawalpindi Medical CollegeMin Xie, MD, PhD – University of Alabama at BirminghamZhihong Yang, PhD – Indiana University

Trainee TravelSyeda H. A. Afroze – Texas A&M Health Science Center College of MedicineHajar Alreefi – Mayo ClinicMounica Bandela – University of Illinois at ChicagoSandra Campos – Rosalind Franklin University of Medicine and ScienceSabena Conley – Mayo ClinicNicole E. Cummings – University of Wisconsin – MadisonPrabhatchandra Dube – University of ToledoSabrina N. Dumas – University of Wisconsin – MadisonCara L. Green – University of Wisconsin – MadisonNatalie Guerrero – University of Wisconsin – MadisonAndrew Hughes – University of Minnesota Medical SchoolNedaa Husainat – University of Kansas Medical CenterAlexadra Iacob – Miller Children’s & Women’s Hospital Long BeachMobashera Jahan – North South University Global Health InstituteSydney Joyner – University of Illinois at ChicagoMohamad A. Kalot – University of Kansas Medical CenterRowan Karaman – University of Wisconsin – MadisonUriel Kim – Case Western Reserve UniversityApurva C. Lad – University of ToledoEvan Noch – Weill Cornell MedicineHeidi Pak – University of Wisconsin – MadisonXinan Qu – University of Illinois at ChicagoSamantha Russell - Rosalind Franklin UniversityMuhammad A. Saeed – University of Nebraska Medical CenterAsh Sampath – University of Missouri School of MedicineAnand Saripalli – Rosalind Franklin UniversityRobin Su – University of Toledo College of Medicine and Life SciencesAli Tug – Mayo ClinicLichun Wang – University of Illinois at Chicago

AWARD WINNERS


GETTING AROUND

Hilton Floor Plan


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SCHEDULE-AT-A-GLANCE

Thursday, April 4th

TIME EVENT LOCATION

8:30 am – 7:00 pm Registration 3rd Floor Foyer

7:00 am – 11:00 am AFMR National Council Meeting Wheaton

10:30 am – 3:00 pm CSCTR Council Meeting New Town

1:00 – 3:00 pm Poster Session A (set-up) Lincoln Park/River North Foyer

1:00 – 3:00 pm MWAFMR Career Development Workshop Lakeshore Ballroom

3:15 – 3:30 pm CSCTR-MWAFMR Welcome Lakeshore Ballroom

3:30 – 4:15 pm MWAFMR Award Presentations Lakeshore Ballroom

4:15 – 5:00 pm New Investigator Session Lakeshore Ballroom

5:00 – 6:30 pm Poster Session A & Opening Reception Lincoln Park/River North Foyer

6:30 – 7:00 pm Poster Session A (take-down) Lincoln Park/River North Foyer

6:30 – 8:00 pm Cardiology/Pulmonary Lecture Wheaton

59th Annual Max Miller Lecture in Diabetes Research Lakeshore Ballroom

7:00 - 9:00 pm Social Event with American Physician Scientists Association

Friday, April 5th

TIME EVENT LOCATION

6:30 am – 3:30 pm Registration 3rd Floor Foyer

7:00 – 8:00 am Mentor Breakfast Wheaton

7:00 – 8:00 am CSCTR Membership Application Processing Streeterville

8:00 – 10:00 am Poster Session B (set-up) Lincoln Park/River North Foyer

8:15 – 9:15 am AFMR Keynote Presentation Lakeshore Ballroom

9:15 – 9:30 am CSCTR Annual Business Meeting Lakeshore Ballroom

9:30 – 10:30 am Department Chair Session I Lakeshore Ballroom

10:30 – 11:30 am Department Chair Session II Lakeshore Ballroom

11:30 am – 1:00 pm Poster Session B & Lunch Lincoln Park/River North Foyer

11:30 am – 1:00 pm Annual Translational Research Editorial Meeting New Town

1:00 – 1:30 pm Poster Session B (take-down) Lincoln Park/River North Foyer

1:15 – 2:15 pm CSCTR John B. Hickam Endowed Lecture Lakeshore Ballroom

1:30 – 3:30 pm Poster Session C (set-up) Lincoln Park/River North Foyer

2:15 – 2:30 pm Translational Research Featured New Investigator Lakeshore Ballroom

2:30 – 3:15 pm Research Innovations Lakeshore Ballroom

3:30 – 4:30 pm Oral Abstract Session I Lakeshore Ballroom

Oral Abstract Session II Wheaton

Oral Abstract Session III Streeterville

4:30 – 6:00 pm Poster Session C & Closing Reception Lincoln Park/River North Foyer

6:00 – 6:30 pm Poster Session C (take-down) Lincoln Park/River North Foyer


MEETING SCHEDULE

Thursday, April 4th

8:30 am – 7:00 pm 3rd Floor Foyer

Registration Desk

1:00 – 3:00 pm Lakeshore Ballroom

MWAFMR Career Development WorkshopModerator: Attaya Suvannasankha, MD, Indiana University School of Medicine

How to Write a Career Development Grant (F or K Award)Dawn Belt Davis, MD, PhD, Associate Professor, University of Wisconsin - Madison

Challenges and Opportunities for Immigrant Physician ScientistsJoumana T. Chaiban, MD, FACE, Associate Professor of Medicine, UIC/Advocate Christ Medical Center


CSCTR-MWAFMR WelcomeModerators: Timothy B. Niewold, MD, New York University; Joumana T. Chaiban, MD, FACE, UIC/Advocate Christ Medical Center


MWAFMR Award PresentationsModerators: Joumana T. Chaiban, MD, FACE, UIC/Advocate Christ Medical Center; Attaya Suvannasankha, MD, Indiana University School of Medicine

AFMR Henry Christian AwardeesA02: CLINICAL BENEFIT OF INTRAVENOUS N-ACETYLCYSTEINE IN PATIENTS WITH ISCHEMIC HEPATOPATHY Shana Kothari, MD, University of Illinois at Chicago/Advocate Christ Medical Center

A09: MAN VS. MACHINE: COMPARISON OF A MACHINE LEARNING ALGORITHM TO CLINICIAN INTUITION FOR PREDICTING INTENSIVE CARE UNIT READMISSION Juan C. Rojas, MD, University of Chicago

Midwest Trainee Travel AwardeesA06: IN VIVO STABLE ISOTOPE LABELING AND QUANTITATIVE MASS SPECTROMETRY IMAGING OF Aβ PLAQUE DEPOSITION AND NEURONAL METABOLISM IN HUMAN AD BRAIN Norelle C. Wildburger, PhD, Washington University in St. Louis

A04: DIETARY ISOLEUCINE IS A KEY REGULATOR OF METABOLIC HEALTH Deyang Yu, University of Wisconsin-Madison

A05: TARGETING CENTRAL BIOMARKERS TO POTENTIATE ACUPUNCTURE ANALGESIA IN SICKLE CELL DISEASE Ying Wang, MD, PhD, University of Minnesota

A03: BIOFILM PRODUCTION IN CLOSTRIDIOIDES (CLOSTRIDIUM) DIFFICILE EPIDEMIC STRAIN DH/NAP11/106 Abdullahi Abdi, BS, Northwestern University Feinberg School of Medicine


New Investigator SessionModerator: Timothy B. Niewold, MD, New York University

Outstanding Young Investigator A01: INVESTIGATING THE IMPACT OF HUMAN GPCR VARIANTS ON METABOLIC HOMEOSTASIS Hongxia Ren, PhD, Indiana University

ECDA Recipient Uncovering Single Cell Endothelial Metabolism Dynamics in Vascular Injury Models David Wu, MD, PhD, University of Chicago

ECDA RecipientA07: SEPSIS DRIVES DAMAGE ASSOCIATED MOLECULAR PATTERN EXPRESSION IN HUMAN BRAIN Benjamin H. Singer, Assistant Professor, University of Michigan Medical School

5:00 – 6:30 pm Lincoln Park/River North Foyer

Poster Session A & Opening Reception

6:30 – 8:00 pm Wheaton

Cardiology/Pulmonary Lecture Moderator: Steven Dudek, MD, University Illinois at Chicago

Using Big Data to Detect Clinical Deterioration Matthew Churpek, MD, PhD, MPH, Assistant Professor of Medicine, University of Chicago

Cell-free Hemoglobin in Sepsis and ARDS: Bedside to Bench and Back Again Lorraine B. Ware MD, Professor of Medicine and Director, Vanderbilt Medical Scholars Program, Vanderbilt University School of Medicine


59th Annual Max Miller Lecture in Diabetes ResearchModerator: Dawn Belt Davis, MD, PhD, University of Wisconsin - Madison

Bilirubin, from Toxic Bile Substance to Metabolic Hormone Terry D. Hinds, Jr., PhD, Assistant Professor, Department of Physiology and Pharmacology, University of Toledo

Insulin/IGF-1 Signaling Controls Muscle Mitochondrial Metabolism and Strength via FoxOs Brian T. O’Neill, MD, PhD, Assistant Professor of Internal Medicine - Endocrinology and Metabolism, University of Iowa Carver College of Medicine

All sessions jointly presented by: Central Society for Clinical and Translational Research & Midwestern Section American Federation for Medical Research


Max Miller Lecture ~ Mechanisms for the Beneficial Effects of Maternal Exercise on Offspring Metabolic Health Laurie J. Goodyear, PhD, Professor of Medicine, Harvard Medical School; Section Head and Senior Investigator, Joslin Diabetes Center

Friday, April 5th

6:30 am – 3:30 pm 3rd Floor Foyer

Registration Desk

7:00 – 8:00 am Wheaton

Mentor Breakfast How to learn from and land leadership positions on Regional and National committees Florence Rothenberg, MS, MD, FACC, Associate Professor, University of Cincinnati; Elissa Klein, Executive Director, American Federation for Medical Research

Sticking up for yourself: Communication and negotiation Suthat Liangpunsakul, MD, MPH, Professor of Medicine, Indiana University School of Medicine

Asking the right questions as you develop your research programRobert McCullumsmith, MD, PhD, Professor and Chair, Department of Neuroscience, Research Director of the Neurosciences Institute, University of Toledo

Becoming an independent investigator: How do I separate myself from my mentor(s) and start my own laboratory? John Dickinson, MD, PhD, Assistant Professor, Associate Director-Adult Cystic Fibrosis Center, Pulmonary Critical Care, Sleep, & Allergy Division, University of Nebraska Medical Center

Navigating authorship: Tips from behind the scenes of a journal Jeffrey Laurence, MD, Professor of Medicine, Weill Cornell Medical College

Funding your research: Writing successful grant applications Joshua A. Englert, MD, Assistant Professor of Internal Medicine, The Ohio State University Wexner Medical Center

Setting priorities: When to say yes and how to say no Gregory M. Vercellotti, MD, FACP, Professor of Medicine, University of Minnesota School of Medicine; Terry G. Unterman, MD, Professor of Medicine, Physiology and Biophysics, University of Illinois at Chicago VA West Side Medical Center

Identifying mentors and maintaining good mentor/mentee relationshipsDawn Belt Davis, MD, PhD, Associate Professor, University of Wisconsin - Madison

The balancing act for women in medicine and scienceAttaya Suvannasankha, MD, Assistant Professor of Clinical Medicine, Indiana University School of Medicine; Jennifer Alexander-Brett, MD, PhD, Assistant Professor of Medicine, Washington University School of Medicine

7:00 – 8:00 am Streeterville

CSCTR Membership Application Processing Timothy B. Niewold, MD, CSCTR President; Abraham Thomas, MD, MPH, CSCTR Past PresidentIf you applied online, meet with Dr. Niewold or Dr. Thomas for a decision on the spot. Upon approval, your name will be listed as a new member during this morning’s Business Meeting.

8:15 – 9:15 am Lakeshore Ballroom

AFMR Keynote PresentationModerator: John D. Dickinson, MD, PhD, University of Nebraska Medical Center

Antimicrobial Bait and Switch: Disruption of Iron-Dependent Metabolism of Pathogenic Microbes using Gallium Bradley Britigan, MD, University of Nebraska Medical Center


CSCTR Annual Business MeetingPresident: Timothy B. Niewold, MD, New York University


Department Chair Session IChair: John M. Carethers, MD, University of Michigan Health System

Sepsis: It Doesn’t Start nor End at the ICU Door Hallie Prescott, MD, MSc, Assistant Professor

Lipidomics Reveal Early Stage Lipid Network Alterations Predictive of Chronic Kidney Disease Progression in Type-2 Diabetes Farsad Afshinnia, MD, Assistant Professor of Medicine

Purinergic Signaling in Venous Thrombosis Yogen Kanthi, MD, Assistant Professor, Cardiovascular & Vascular Medicine


Department Chair Session IIChair: Ravi Durvasula, MD, Loyola University

Alcohol, Advanced Lung Disease, and Lung Transplant Erin Lowery, MD, MS, Associate Professor

Sulfonyluera Receptor 2 (SUR2) Regulates Cardiac Substrate Utilization Gregory Aubert, MD, PhD, Assistant Professor

Next Generation Sequencing in Cellular Immune Therapy Nasheed Hossain, MD, Assistant Professor

11:30 am – 1:00 pm Lincoln Park/River North Foyer

Poster Session B & Lunch

MEETING SCHEDULE



CSCTR John B. Hickam Endowed LectureModerator: Terry G. Unterman, MD, University of Illinois at Chicago VA West Side Medical Center

Cell Death and Sterile Inflammation in Liver Injury and FibrosisAriel Feldstein, MD, Professor of Pediatrics, Chief, Division of Pediatric Gastroenterology, Hepatology, and Nutrition, University of California, San Diego


Translational Research Featured New InvestigatorModerator: Jeffrey Laurence, MD, Weill Cornell Medical College

Stimulation of the Endogenous Incretin Glucose-Dependent Insulinotropic Peptide by Enteral Dextrose Improves Glucose Homeostasis and Inflammation in Murine EndotoxemiaFaraaz Ali Shah, MD, Assistant Professor of Medicine, University of Pittsburgh Medical Center


Research InnovationsModerator: Timothy B. Niewold, MD, New York University

Novel Tools for Connecting Biological Disease Signatures with DrugsRobert McCullumsmith, MD, PhD, Professor and Chair, Department of Neuroscience, Research Director of the Neurosciences Institute, University of Toledo


Oral Abstract Session IModerator: J. Brian Byrd, MD, MS, University of Michigan

C12: INCIDENTAL DIAGNOSIS OF CARDIAC AMYLOIDOSIS IN AN 86-YEAR-OLD WITH MGUS - AL OR aTTR? Pratik S. Velangi, MD, University of Minnesota

C14: A RARE CASE OF INFECTIOUS PSEUDOANEURYSM DUE TO ASPERGILLUS FLAVUS IN THE SETTING OF RENAL TRANSPLANT Samia Asif, MD, University of Missouri - Kansas City

C13: CHRYSEOBACTERIUM INDOLOGENES BACTEREMIA IN CIRRHOSIS Jaspreet S. Suri, MD, Beth Israel Deaconess Medical Center

C10: APPROPRIATE USE OF TELEMETRY: INDICATION VERSUS GRATIFICATION Julien Feghaly, MD, St. Louis University Hospital

C11: APICAL HYPERTROPHIC CARDIOMYOPATHY: A DIAGNOSTIC DILEMMA Najia Waheed, MBBS, Rawalpindi Medical College

3:30 – 4:30 pm Wheaton

Oral Abstract Session II Moderator: Sidharth Mahapatra, MD, PhD, University of Nebraska Medical Center

C07: AUTOPHAGY FACILITATES MITOCHONDRIAL BIOGENESIS TO MAINTAIN MITOCHONDRIAL HOMEOSTASIS DURING CARDIAC ISCHEMIA/REPERFUSION INJURY Min Xie, MD, PhD, University of Alabama at Birmingham

C08: ROLE OF UCHL1 IN RADIATION-INDUCED LUNG INJURY MEDIATED BY SPHINGOLIPIDS Yulia Epshtein, PhD, University of Illinois at Chicago

C06: ENDOTHELIAL CELL INTEGRIN BETA4 KNOCKOUT ATTENUATES LPS-INDUCED MURINE ACUTE LUNG INJURY Weiguo Chen, MD, PhD, University of Illinois at Chicago

C05: Gq-MEDIATED PKD ACTIVATION INDUCES ABERRANT MITOCHONDRIAL FISSION THROUGH PHOSPHORYLATION OF DLP1 IN CARDIOMYOCYTES Bong Sook Jhun, PhD, University of Minnesota

3:30 – 4:30 pm Streeterville

Oral Abstract Session IIIModerator: Mohammad N. Uddin, PhD, FAHA, Orion Institute for Translational Medicine, Texas A&M University College of Medicine

3:30 – 3:44 C03: TARGETED DISRUPTION OF NA/K-ATPASE- SRC SIGNALING CASCADE SIGNIFICANTLY REDUCES RENAL INFLAMMATION AND OXIDATIVE STRESS FOLLOWING 5/6th PARTIAL NEPHRECTOMY Fatimah K. Khalaf, MB ChB, University of Toledo

3:45 – 3:59 C04: ALGINATE OLIGOSACCHARIDE ALLEVIATES D-GLACTOSE-INDUCED CARDIAC AGING IN MICE VIA REGULATING THE SIRT1/PGC-1A SIGNALING PATHWAY Wenjing Feng, MD, Qingdao University

4:00 – 4:14 C01: OVEREXPRESSION OF LONG NON-CODING RNA H19 REGULATED THE METHIONINE METABOLISM IN ALCOHOLIC LIVER DISEASE Zhihong Yang, PhD, Indiana University

4:15 – 4:29 C02: ABLATING ADIPOSE CREB3L3 PRESERVES METABOLIC HEALTH DURING OBESITY Maximilian McCann, BS, University of Illinois at Chicago


Poster Session C & Closing Reception

MEETING SCHEDULE


FEATURED PRESENTERS

MWAFMR Career Development WorkshopJoumana T. Chaiban, MD, FACEUIC/Advocate Christ Medical CenterAfter completing her Endocrinology Fellowship at Case Western Reserve University in Cleveland, Ohio, Dr Chaiban joined Saint Vincent Charity Medical Center where she was the Medical Director for the Joslin Diabetes Affiliate and then served as the

Head of their Endocrinology Division and Chairperson of the IRB committee. She joined the Division of Endocrinology, Metabolism and Lipid Research at Washington University in July 2015. She practices General Endocrinology with a particular interest in Diabetes and Obesity.

Dawn Belt Davis, MD, PhDUniversity of Wisconsin – MadisonDr. Davis runs a federally funded research lab focused on pancreatic beta cell biology. She focuses on understanding the mechanisms underlying the growth response in the beta cell and in beta cell death or apoptosis. Dr. Davis also conducts

clinical research in collaboration with a number of other investigators. She has led a study to understand the mechanisms of hypoglycemia in gastric bypass surgery patients and to test a novel treatment for this disorder. She has ongoing collaborative studies looking at biomarkers for diabetes, novel dietary interventions for weight loss and diabetes prevention, and the treatment of diabetes in hospitalized patients.

Cardiology/Pulmonary LectureMatthew Churpek, MD, PhD, MPHUniversity of ChicagoDr. Churpek is an Assistant Professor of Medicine in the Section of Pulmonary and Critical Care at the University of Chicago. His research involves using electronic health record data to develop machine learning models to detect clinical deterioration in

hospitalized patients. Dr. Churpek’s work has been supported by NIH K08 and R01 awards and an American Thoracic Society Foundation Recognition Award for Outstanding Early Career Investigators.

Lorraine B. Ware, MDVanderbilt University School of MedicineDr. Ware is a physician scientist and practicing intensivist at Vanderbilt University in the Division of Allergy, Pulmonary and Critical Care Medicine. Her research program focuses on Acute Respiratory Distress Syndrome including pathogenesis, biomarkers for

diagnosis and prognosis and development of new targeted therapies. She is actively engaged in mentoring the next generation of physician scientists as director of an NIH T32 training grant, director of the Vanderbilt Medical Scholars medical student research program and as a faculty advisor to the Vanderbilt MSTP program.

Max Miller Lecture in Diabetes ResearchLaurie J. Goodyear, PhDHarvard Medical SchoolDr. Laurie J. Goodyear received her B.S. from Springfield College in Massachu-setts, her M.S. from the University of South Carolina, and her Ph.D. from the University of Vermont. She is Professor of Medicine at Harvard Medical School and a Senior Investigator at the Joslin

Diabetes Center and. At Joslin, she serves as the Co-Head of the Section on Integrative Physiology and Metabolism, the Director of the NIH-funded Diabetes Research Center Animal Physiology Core, and the Director of the Clinical Exercise Physiology Research Laboratory. She has re-ceived numerous awards and honors, has published more than 200 papers and has given over 160 invited lectures at national and international conferences. The Goodyear laboratory investigates the underlying molecular mech-anisms that mediate the beneficial effects of exercise to improve metabolic health. The Goodyear lab has made numerous, fundamental discoveries on how exercise regulates multiple signaling pathways in skeletal muscle, most notably her studies of AMPK. Currently, Dr. Good-year is the PI of a Preclinical Animal Study Site (PASS) as part of the NIH-funded Molecular Transducers of Physical Activity in Humans Consortium (MoTrPAC), the goal of which is to determine the molecular footprint underly-ing the benefits of exercise on health. In addition to the consortium work, her lab has recently conducted ground-breaking studies in two areas of investigation. First, they have shown that exercise training causes adaptations to adipose tissue that improve overall glucose homeostasis. Second, they have discovered that maternal and paternal exercise has profound beneficial effects on the metabolic health of adult offspring, and elucidated novel epigenetic mechanisms for these effects. All of this work has import-ant ramifications for the prevention and treatment of numerous chronic diseases in humans.


FEATURED PRESENTERS

Terry D. Hinds, Jr., PhDUniversity of ToledoDr. Hinds obtained his BS in Biology from Shawnee State University and his PhD in Medical Sciences, Cardiovascular and Metabolic Diseases at the University of Toledo. He also completed a postdoctoral fellowship at University of Toledo and joined

the faculty as an assistant professor in the Department of Physiology and Pharmacology in 2013. He also has joint appointments with the Department of Urology and with the Department of Kinesiology at University of North Carolina – Charlotte. His lab looks at how nuclear receptors signal for organismal metabolic balance and glucose homeostasis, including in cancer. Recently, his lab discovered an unexpected role for bilirubin as a ligand for nuclear receptors (PPARalpha) to attenuate metabolic diseases. This work has opened new avenues for therapy and drug targeting, and has led to two published international patents.

Brian T. O’Neill, MD, PhDUniversity of Iowa Carver College of MedicineBrian O’Neill is an assistant professor and endocrinologist at the University of Iowa, Carver College of Medicine. He received his MD/PhD from the University of Utah and completed post-graduate training at Beth Israel

Deaconess Medical Center and Joslin Diabetes Center, affiliates of Harvard Medical School. There Dr. O’Neill discovered that insulin receptors and IGF-1 receptors coordinate muscle growth and suppress atrophy by regulating FoxO transcription factors. Dr. O’Neill’s current and future plans involve investigating the roles of insulin signaling and FoxO regulation in the control of muscle strength and mitochondrial metabolism, in hopes of identifying the abnormalities that occur in the diabetic state. The ultimate goal of Dr. O’Neill’s research is to provide therapeutic targets that benefit muscle energy production in diabetes, speed recovery after severe illness or surgery, and prevent disability.

AFMR KeynoteBradley E. Britigan, MDUniversity of Nebraska Medical CenterA Minnesota native who grew up in St. Louis, Dr. Britigan, an internal medicine/infectious disease specialist, was named dean of the UNMC College of Medicine in 2011 after seven years at the University of Cincinnati as chair of internal medicine which was preceded

by 17 years at the University of Iowa. He also has had a 25-year relationship with the VA. Dr. Britigan also serves as president of UNMC’s partner, Nebraska Medicine.

Dr. Britigan places a high value on research. His own research focuses on bacterial infections of the lungs. During his academic career, his research has been primarily funded by the National Institutes of Health and the VA. He is a Past President of the American Federation for Medical Research, as well as a member of the American Society of Clinical Investigation and the Association of American Physicians.

Department Chair Session IUniversity of Michigan

John M. Carethers, MD, ChairDr. Carethers’ research interests include familial cancer and polyposis syndromes, mechanisms of tumor progression, tumor genetics, tumor markers, DNA mismatch repair, molecular pathology, TGF-beta superfamily signaling in cancer

progression, and colorectal cancer disparities.

Dr. Carethers’ clinical interests are familial colon cancer syndromes, including familial adenomatous polyposis (FAP), Gardner, Peutz-Jeghers, Lynch, hereditary nonpolyposis colorectal cancer (HNPCC), juvenile polyposis, hyperplastic polyposis, and colorectal cancer.

Farsad Afshinnia, MDDr. Afshinnia joined the nephrology fellowship program as a fellow at the University of Michigan in 2010. After graduation he then joined the faculty at the division of nephrology at Michigan Medicine in 2012. Currently, he is in the 4th year of a K08 award. He has published over 30 original

research papers. His research interests are application of metabolomics in biomarker discovery and risk stratification at early stage.


Yogendra Kanthi, MDDr. Kanthi is a Cardiologist and Vascular Medicine specialist at the University of Michigan. He completed his residency (2008) and served as Chief Medical Resident (2009) in Internal Medicine at University Hospitals Case Medical Center in Cleveland. He completed clinical

fellowships in Cardiology (2013) and Vascular Medicine (2014) and a research fellowship in vascular biology at the University of Michigan. His areas of clinical interest include peripheral vascular disease, venous thromboembolism, chronic venous disease, general and preventive cardiology, aneurysmal disease, aortic disease and anticoagulation. He has an active translational research laboratory investigating the mechanisms of inflammation and thrombosis in vascular biology.

Hallie Prescott, MD, MScDr. Prescott is an Assistant Professor in pulmonary/critical care and at University of Michigan and the Ann Arbor VA hospital. Her research examines the impact of sepsis on patient’ long-term health. She is vice chair of the Surviving Sepsis Campaign

Guidelines and a council member of the International Sepsis Forum.

Department Chair Session IILoyola University

Ravi Durvasula, MD, ChairDr. Durvasula earned his medical degree from McGill University in Montreal. He completed a residency in internal medicine at Baylor College of Medicine/Methodist Hospital in Houston, where he was chief medical resident. He completed a fellowship in infectious diseases at Yale University

School of Medicine and was awarded the prestigious physician postdoctoral fellowship of the Howard Hughes Medical Institute. He is board certified in internal medicine and infectious diseases.

In 2017 Dr. Durvasula was named chair of the department of medicine of Loyola Medicine and Loyola University Chicago Stritch School of Medicine. He held senior leadership positions at Yale University and the Veterans Administration and has conducted groundbreaking research in global infectious diseases. Most recently, he was a professor of medicine and infectious diseases and director of the Center for Global Health at the University of New Mexico School of Medicine. The center has partnered with 13 medical centers in India, Kenya, China and Colombia.

Gregory Aubert, MD, PhDMD-PhD from University of Lausanne Switzerland, Postdoctoral training at Sanford Burnham Medical research Institute in Dr. D. P. Kelly laboratory, Internal Medicine Residency at UT Southwestern, Cardiology Fellowship at Northwestern University in the Physician scientist training program.

Erin Lowery, MD, MSErin Lowery is an Associate Professor of Medicine and Pediatrics at Loyola University Chicago. She completed an adult pulmonary and critical care fellowship at Loyola University Medical Center and her clinic expertise is in cystic fibrosis and lung transplantation. Dr. Lowery is supported by the

National Institute of Alcohol Abuse and Alcoholism and the Cystic Fibrosis Foundation, and her research focuses on examining alcohol misuse in the context of lung transplantation and advanced lung disease, the use of alcohol biomarkers to identify alcohol misuse, the impact alcohol misuse has on health outcomes, and alcohol’s role in impairing airway inflammation.

Nasheed Hossain, MDAssistant Professor of Medicine and junior lead for Cancer Cell Therapies at Loyola University. Has a research focus on the T-cell biology of Cellular Immune Therapy and how this may enhance clinical efficacy and reduce toxicities.

FEATURED PRESENTERS


FEATURED PRESENTERS

John B. Hickam Endowed LecturerAriel Feldstein, MDUniversity of California, San DiegoDr. Ariel Feldstein is Chief of the Gastroenterology, Hepatology & Nutrition Division at Rady Children’s Hospital-San Diego and a Professor of Pediatrics at UC San Diego School of Medicine. After graduating from the Univ. of Buenos Aires and completing

a postdoctoral program in physiology at the Mayo Clinic, Dr. Feldstein went on to become the Director of Research for the Pediatric Institute at the Cleveland Clinic before moving to San Diego in 2011. He is a renowned Pediatric Hepatologist who pioneered the development of non-invasive blood tests to monitor liver damage and discovered novel targets for NASH and liver fibrosis treatment for which he holds various patents. He is an innovator and an entrepreneur being the founder of two Biotech Companies, Torrey Pines Metabolic Health Labs and Jecure Therapeutics (acquired by Genentech/Roche in 2018). His lab focuses on molecular mechanisms of acute and chronic liver injury, their links to fibrosis and hepatocarcinogenesis, and serum-based biomarkers to monitor liver damage non-invasively.

Research InnovationsRobert McCullumsmith, MD, PhDUniversity of Toledo Medical CenterDr. McCullumsmith studied biochemistry (BS) at Indiana University, then pursued joint MD, PhD degrees at the University of Michigan. Following a research-track residency in Psychiatry at the University of Michigan, he joined the faculty and

began to study abnormalities of glutamate transporter expression in severe mental illness. Dr. McCullumsmith was promoted to Associate Professor with Tenure while at the Department of Psychiatry and Neurobiology at the University of Alabama-Birmingham. Dr. McCullumsmith relocated to the University of Cincinnati in 2013, and sees patients at the Cincinnati Veteran’s Affairs Medical Center and the University of Cincinnati Department of Psychiatry.

Editor-in-Chief: Michael J. McPhaul, MD

Associate EditorsRichard Auchus, MD, PhD

Keith Colburn, MDRobert J. Freishtat, MD, MPH

Taylor Harrison, MDRichard A. Lange, MD

Suthat Liangpunsakul, MDMingMing Ning, MD, MMsc

Don Rockey, MDPeter Noel Van Buren, MD

Peter H. Wiernik, MD

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Thursday, April 4th


Poster Session A

A01: INVESTIGATING THE IMPACT OF HUMAN GPCR VARIANTS ON METABOLIC HOMEOSTASISHongxia Ren, Shijun Yan, Austin Reilly, Jason Conley, Rong Chen Indiana University School of Medicine, IN

A02: CLINICAL BENEFIT OF INTRAVENOUS N-ACETYLCYSTEINE IN PATIENTS WITH ISCHEMIC HEPATOPATHYShana Kothari, Michael Kalinowski, Elizabeth Brindise, Matthew Kobeszko, Rogelio Silva University of Illinois at Chicago/Advocate Christ Medical Center, IL

A03: BIOFILM PRODUCTION IN CLOSTRIDIOIDES (CLOSTRIDIUM) DIFFICILE EPIDEMIC STRAIN DH/NAP11/106Abdullahi Abdi, Aakash Balaji, Egon A Ozer, Larry K. Kociolek Northwestern University Feinberg School of Medicine, IL

A04: DIETARY ISOLEUCINE IS A KEY REGULATOR OF METABOLIC HEALTHDeyang Yu1 2 3, Nicole E. Cummings1 2 4, Cara L. Green1 2, Alexandra Spicer5, Victoria Flores1 6, Cholsoon Jang7, Ildiko Kasza8, Maria Nikodemova5, Matt H. Wakai1 2, Jay L. Tomasiewicz2, Shany E. Yang1 2, Blake R. Miller1 2, Heidi H. Pak1 2, Jacqueline A. Brinkman1

2, Caroline M. Alexander8, Joshua D. Rabinowitz7, Joseph A. Baur9, Kristen C. Malecki5, Dudley W. Lamming1 2 3 4 6 1Department of Medicine, University of Wisconsin – Madison, Madison, WI, USA; 2William S. Middleton Memorial Veterans Hospital, Madison, WI, USA; 3Molecular and Environmental Toxicology Program, University of Wisconsin – Madison, Madison, WI, USA; 4Endocrinology and Reproductive Physiology Graduate Training Program, University of Wisconsin – Madison, Madison, WI, USA; 5Department of Population Health Sciences, School of Medicine and Public Health, University of Wisconsin – Madison, Madison, Wisconsin, USA; 6Interdisciplinary Graduate Program in Nutritional Sciences, University of Wisconsin – Madison, Madison, WI, USA; 7Department of Chemistry and Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ, USA; 8McArdle Laboratory for Cancer Research, University of Wisconsin – Madison, Madison, WI, USA; 9Department of Physiology, University of Pennsylvania, Philadelphia, PA, USA

A05: TARGETING CENTRAL BIOMARKERS TO POTENTIATE ACUPUNCTURE ANALGESIA IN SICKLE CELL DISEASEYing Wang, Jianxun Lei, Kalpna Gupta Vascular Biology Center, Division of Hematology, Oncology & Transplantation, Department of Medicine, University of Minnesota, MN

A06: IN VIVO STABLE ISOTOPE LABELING & QUANTITATIVE MASS SPECTROMETRY IMAGING OF Aβ PLAQUE DEPOSITION AND NEURONAL METABOLISM IN HUMAN AD BRAINNorelle C. Wildburger, Gregory S. Day, Wendy Sigurdson, Lauren Watkins, Robert E. Schmidt, Randall J. Bateman Washington University in St. Louis, MO

A07: SEPSIS DRIVES DAMAGE ASSOCIATED MOLECULAR PATTERN EXPRESSION IN HUMAN BRAINBenjamin H. Singer1, Angela C. Bustamante1, Kristopher Opron1, Paul Crane2, C. Dirk Keene2, Theodore Standiford1 1University of Michigan Medical School, MI; 2University of Washington, WA

A08: SINGLE CELL METABOLISM REVEALS THAT A RHOA-MEDIATED GLYCOLYTIC BURST DRIVES ENDOTHELIAL CELL CONTRACTIONSDavid Wu1, Devin Harrison1, Recep Nigdelioglu2, Yun Fang1, Gokhan Mutlu1 1University of Chicago, IL; 2Loyola University Medical Center, IL

A09: MAN VS. MACHINE: COMPARISON OF A MACHINE LEARNING ALGORITHM TO CLINICIAN INTUITION FOR PREDICTING INTENSIVE CARE UNIT READMISSIONJuan C. Rojas1, Patrick G. Lyons2, Megha Kilaru1, Kyle A. Carey1, Laura R. Venable1, Jamila Picart1, Leslie Mccauley1, Vineet Arora1, Dana P. Edelson1, Matthew M. Churpek1 1University of Chicago, IL; 2Washington University, MO

ABSTRACT POSTER TITLES & AUTHORS

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ABSTRACT POSTER TITLES & AUTHORSThursday, April 4th continued

A10: GHRELIN-INDUCED ADIPOSE TISSUE DYSFUNCTION: ROLE IN ALCOHOLIC STEATOSISKaruna Rasineni, Kurt L. Knight, Carol A. Casey, Kusum K. Kharbanda UNMC, NE

A11: NON-MUSCLE MYOSIN LIGHT CHAIN KINASE ACTIVITY MEDIATES ENDOTHELIAL CELL PROLIFERATION AND INHIBITS APOPTOSIS IN PULMONARY ARTERIAL HYPERTENSIONMariam Anis, Rachel Halstrom, Noman Baig, Jeffrey R. Jacobson, Dustin R. Fraidenburg University of Illinois at Chicago, Department of Medicine, Chicago, IL, USA, IL

A12: SYSTEMS ENGINEERING GUIDED ANTIBIOTIC STEWARDSHIP INTERVENTION DEVELOPMENT FOR SKIN AND SOFT TISSUE INFECTIONSMichael Pulia, Steven Hesse, Rebecca Schwei University of Wisconsin – Madison, WI

A13: MIR-1253 IS A NOVEL TUMOR SUPPRESSOR GENE IN MEDULLOBLASTOMARanjana Kanchan1, Naveen Kumar Perumal1, Ishwor Thapa2, Mohd. Wasim Nasser1, Deborah Perry3, Surider Batra1, Sidharth Mahapatra1 1University of Nebraska Medical Center, NE; 2University of Nebraska at Omaha, NE; 3Children’s Hospital and Medical Center, NE.

A14: VELIPARIB PROTECTS AGAINST NEURODEGENERATION AND PHOSPHOLIPASE A2-MEDIATED NEUROINFLAMMATION IN BINGE ALCOHOL-EXPOSED ADULT RATS Dimitrios E. Kouzoukas1, Jennifer A. Schreiber1, Nuzhath F. Tajuddin1, Simon Kaja1, Hee-Yong Kim2, Michael A. Collins1 1Loyola University Chicago, IL; 2National Institute of Alcoholism and Alcohol Abuse, MD

A15: MECHANISM-BASED, IN-VITRO INHIBITION OF MYCOBACTERIUM ABSCESSUS: ASSESSING BETA LACTAM THERAPYKhalid M. Dousa1, Sebastian Kurz2, Christopher R. Bethel3, Melissa D. Barnes4, Suresh Selvaraju5, Michael R. Jacobs6, Barry N. Kreiswirth7, Robert A. Bonomo8 1University Hospitals Cleveland Medical Center, Case Western Reserve University, Division of Infectious Diseases, Cleveland, OH;

2Mount Sinai National Jewish Health Respiratory Institute, New York City, NY; 3Research Service, Louis Stokes Veterans Affairs Medical Center, Cleveland, OH; 4Research Service, Louis Stokes Veterans Affairs Medical Center, Cleveland, Ohio, USA. Department of Medicine, Case Western Reserve University School of Medicine, OH; 5Department of Microbiology, Metrohealth Medical Center, Cleveland, OH; 6Departments of Pathology, Case Western Reserve University School of Medicine; 7Public Health Research Institute, Rutgers New Jersey Medical School, Newark, NJ; 8Department of Medicine, Pharmacology, Molecular Biology and Microbiology, Biochemistry, and Proteomics and Bioinformatics, Case Western Reserve University School of Medicine, Louis Stokes Cleveland Department of Veterans Affairs Medical Center, OH

A16: LOSS OF HEPATOCYTE-SPECIFIC PPAR GAMMA EXPRESSION AMELIORATES DIET-INDUCED NON-ALCOHOLIC STEATOHEPATITISGregory H. Norris, Danielle C. Pins, Jose Muratalla, Jose Cordoba-Chacon University of Illinois at Chicago, IL

A17: NOVEL PHARMACOLOGICAL APPROACH TO TREAT VASCULAR LEAKAGEXinyan Qu, Ben Hitchinson, Avik Banerjee, Shuangping Zhao, Chongxu Zhang, Vadim Gaponenko, Yulia Komarova University of Illinois – Chicago, IL

A18: SEX AND STRAIN DETERMINE THE METABOLIC RESPONSE TO DIETARY PROTEIN LEVELCara L. Green, Heidi H. Pak, Victoria Flores, Nicole E. Cummings, Katherine Kredell, Shany E. Yang, Deyang Yu, Jay Tomasiewicz, Sabrina N. Dumas, Dudley W. Lamming University of Wisconsin – Madison, WI

A19: THE MICROENVIRONMENT OF THE JUVENILE LUNG PROMOTES EXCESS INFLAMMATION IN INFLUENZA A VIRUS INFECTIONBria Coates, Margaret Turner, Christina Sul, Mark Ciesielski, Karen Ridge Northwestern University, IL



A20: MITOCHONDRIAL CALCIUM AND REACTIVE OXYGEN SPECIES CONTROL CARDIAC FIBROBLAST PROLIFERATIONJin O-Uchi, Stephanie M. Adaniya, Yuta Suzuki, Michael W. Cypress, Bong Sook Jhun University of Minnesota, MN

A21: THE ROLE OF RMTG-MEDIATED COCAINE AVERSION IN ADDICTIONMaya Eid Medical University of South Carolina, SC

A22: ASSOCIATION BETWEEN TEMPERATURE TRAJECTORY AND CYTOKINE SIGNATURES IN PATIENTS WITH STAPHYLOCOCCUS AUREUS BACTEREMIASiva Bhavani, Jared Greenberg, Kyle Carey, Anne Sperling, Matthew M. Churpek, Philip A. Verhoef University of Chicago, IL

A23: IMPROVING SYPHILIS DIAGNOSIS AND TREATMENTIN AN URBAN POPULATION THROUGH ROUTINE EMERGENCY DEPARTMENT SCREENINGKimberly Stanford, Jessica Ridgway, John Schneider University of Chicago, IL

A24: COMPARATIVE IN-VITRO STUDY OF SUSCEPTIBILITIES OF ERAVACYCLINE, TIGECYCLINE AND MINOCYCLINE AGAINST MULTI-DRUG RESISTANT ACINETOBACTER BAUMANNIUdita Chapagain, Monica Stumpf, Najwa Pervin, Vidya Sundareshan Southern Illinois University School of Medicine, IL

A25: INCREASED HOMOCYSTEINEMIA AND URINE BETAINE EXCRETION IN PATIENTS WITH EARLY AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE (ADPKD)Hajar Alreefi, Ivan Vuckovic, Song Zhang, Slobodan Macura, Fouad Chebib, Peter Harris, Alfonso Eirin, Lilach Lerman, Vicente Torres, Maria V. Irazabal Mayo Clinic, MN

A26: UNCOVERING THE ROLE OF FASTING AND REDUCED CALORIC INTAKE IN THE METABOLIC BENEFITS OF CALORIE RESTRICTIONHeidi H. Pak, Cara L. Green, Nicole E. Cummings, Jacqueline A. Brinkman, Shany Yang, Deyang Yu, Jay Tomasiewicz, Matthew Wakai, Dudley Lamming University of Wisconsin – Madison, WI

A27: DEFICIENCY OF AUTOPHAGY REGULATORY PROTEIN, ATG16L1, INCREASE AIRWAY EPITHELIAL SECRETORY MUCINS MUC5AC AND MUC5B.John Dickinson1, Jenea Sweeter1, Steve Brody2 1University of Nebraska Medical Center, NE; 2Washington University School of Medicine, MO

A28: MITOCHONDRIAL EXPRESSION OF THE CALCIUM-ACTIVATED CHLORIDE CHANNEL ANOCTAMIN-1 IN PULMONARY ARTERY ENDOTHELIAL CELLSMichael W. Cypress1, Stephanie Adaniya1, Yuta Suzuki1, Richard Clements2, Jin O-Uchi1, Bong Sook Jhun1, Gaurav Choudhary2 1University of Minnesota, MN; 2Brown University, RI

A29: ASSESSMENT OF LIVER ENZYMES FOR THE DIAGNOSIS OF MICROCYSTIN INDUCED HEPATOTOXICITY IN THE SETTING OF PRE-EXISTING LIVER DISEASERobin Su, Apurva Lad, Andrew Kleinhenz, Steven T. Haller, David J. Kennedy The University of Toledo College of Medicine and Life Sciences, OH

A30: CHOLESTEROL-INDEPENDENT REQUIREMENT OF SREBP-2 FOR THE SURVIVAL OF INTESTINAL ADENOMASLuke J. Engelking University of Texas – Southwestern, TX



A31: A COMPARISON OF CHARACTERISTICS IN LEFT VENTRICULAR ASSIST DEVICE PATIENTS WITH AND WITHOUT GASTROINTESTINAL BLEEDINGMichael Kalinowski, Shana Kothari, Matthew Kobeszko, Greta Josephson, William Cotts, Sunil Pauwaa, Antone Tatooles, Rogelio Silva, Imad Elkhatib University of Illinois at Chicago – Advocate Christ Medical Center, IL

A32: HEPATIC INJURY ASSOCIATED WITH REDUCED URINARY EXCRETION AND ALTERED HEPATIC SIGNALING PATHWAYS FOLLOWING CHRONIC LOW DOSE EXPOSURE TO MICROCYSTIN-LR IN A MURINE MODEL OF NON-ALCOHOLIC FATTY LIVER DISEASEApurva C. Lad1, Robin Su1, Joshua D. Breidenbach1, Nicholus Carruthers2, Paul Stemmer3, Dilrukshika Palagama1, David Baliu-Rodriguez1, Dragan Isailovic1, Steven T. Haller1, David J. Kennedy1 1University of Toledo, OH; 2Wayne State University, OH; 3Wayne State University, MI

A33: THE DIGITAL CHICAGO ASTHMA PLAN (DCAPE) FOR EVERYONE: MULTI-DISCIPLINARY COLLABORATION TO CREATE AN INTERACTIVE WEB-BASED ASTHMA ACTION PLANAndrea A. Pappalardo1, Houshang Darabi1, Tom MacAvish2, Molly A. Martin1 1University of Illinois at Chicago, IL; 2Illinois Institute of Technology Institute of Design, IL

A34: IN VITRO ACTIVITY OF ERAVACYCLINE AND OTHER TETRACYCLINES ON EXTENDED SPECTRUM BETA-LACTAMASE PRODUCING CLINICAL ISOLATES OF GRAM NEGATIVE ORGANISMMonica Stumpf, Udita Chapagain, Vidya Sundareshan Southern Illinois University School of Medicine, IL

A35: OBESITY INDUCES MESENCHYMAL STEM CELL SENESCENCE AND DYSFUNCTIONSabena M. Conley, LaTonya J. Hickson, Hui Tang, Kyra L. Jordan, Abdelrhman M. Abumoawad, Seo Rin Kim, Xiang-Yang Zhu, Tamar Tchkonia, James L. Kirkland, Lilach O. Lerman Mayo Clinic, MN

A36: BETAINE INSUFFICIENCY AND REDUCED BETAINE DEPENDENT REMETHYLATION ARE ASSOCIATED WITH HYPERHOMOCYSTEINEMIA AND VASCULAR ABNORMALITIES IN EARLY POLYCYSTIC KIDNEY DISEASEAli Tug, Ivan Vuckovic, Alexis Adrian, Slobodan Macura, Fouad Chebib, Peter Harris, Alfonso Eirin, Lilach Lerman, Vicente Torres, Maria V. Irazabal Mayo Clinic, MN

A37: ENHANCER PROFILING REVEALS REGULATORS OF SKELETAL MUSCLE IDENTITY AND REPROGRAMMINGKrithika Ramachandran, Madhavi D. Senagolage, Meredith A. Sommars, Christopher Futtner, Yasuhiro Omura, Grant D. Barish Northwestern University, IL

A38: MYOCARDIAL FIBROSIS AND PROGNOSIS IN HEART TRANSPLANT RECIPIENTSAndrew Hughes1, Osama Okasha1, Afshin Farzaneh-Far2, Felipe Kazmirczak1, Prabhjot S. Nijjar1, Pratik Velangi1, Cindy M. Martin1, Mehmet Akcakaya3, Chetan Shenoy1 1Cardiovascular Division, Department of Medicine, University of Minnesota Medical School, MN; 2Section of Cardiology, Department of Medicine, University of Illinois at Chicago, IL; 3Department of Electrical and Computer Engineering and Center for Magnetic Resonance Research, University of Minnesota, MN

A39: NOVEL PEPTIDE B7-33 AND RELAXIN HORMONES PROTECT CYTOTROPHOBLASTS FROM PREECLAMPSIA PHENOTYPESyeda H. Afroze1, Ahmed F. Pantho1, David C. Zawieja1, Ross Bathgate2, Thomas J. Kuehl3, Mohammed A. Hossain4, Mohammad N. Uddin5 1Texas A&M Health Science Center College of Medicine, TX; 2Florey Institute of Neuroscience and Mental Health, University of Melbourne; 3Baylor Scott & White, TX; 4Florey Institute of Neuroscience and Mental Health, University of Melbourne, TX; 5Orion Institute for Translational Medicine, TX



A40: SJÖGREN’S SYNDROME IS ASSOCIATED WITH REDUCED SEX HORMONE EXPOSURE: A CASE-CONTROL STUDYSara Mccoy1, Emmanuel Sampene1, Alan Baer2 1University of Wisconsin, WI; 2Johns Hopkins University School of Medicine, MD

A41: A NOVEL DUAL ACTING MOLECULE TREATS DIABETIC NEPHROPATHY IN RATSMd Abdul H. Khan1, Sung H. Hwang2, Bruce D. Hammock2, John D. Imig1 1Department of Pharmacology & Toxicology, Medical College of Wisconsin, WI; 2Department of Entomology & Cancer Center, University of California, CA

A42: REGULATION OF BODY WEIGHT AND COMPOSITION BY DIETARY HISTIDINEVictoria Flores1, Alexandra Spicer2, Nicole Cummings1, Eunhae Park1, Maria Nikodemova2, Deyang Yu3, Shany Yang3, Jay Tomasiewicz3, Kristen Malecki2, Dudley Lamming4 1Department of Medicine, University of Wisconsin – Madison, Madison, WI; 2Department of Population Health Sciences, University of Wisconsin – Madison, Madison, WI; 3William S. Middleton Memorial Veterans Hospital, Madison, WI; 4Department of Medicine, University of Wisconsin – Madison, WI

A43: PROGNOSTIC VALUE OF INFLAMMATORY MARKERS DURING TREATMENT OF PROSTHETIC JOINT INFECTIONMohamad A. Kalot, Upasna Manchanda, Wissam El Atrouni, Albert Eid University of Kansas Medical Center, MO

A44: CHEK2 MUTATIONS AS PREDISPOSITION ALLELES FOR INHERITED HEMATOPOIETIC MALIGNANCIESImo J. Akpan, MD, PhD The University of Chicago

A45: AUTOPHAGY AND PGC1ALPHA-DEPENDENT MITOCHONDRIAL BIOGENESIS ARE ESSENTIAL TO PREVENT CARDIAC REPERFUSION INJURYMin Xie, MD, PhD University of Alabama at Birmingham


Friday, April 5th


Poster Session B

B01: A COMPARISON OF FIRST TIME GASTROINTESTINAL BLEEDING EVENTS BETWEEN HEARTMATE II AND HEARTWARE LEFT VENTRICULAR ASSIST DEVICESMichael Kalinowski, Shana Kothari, Matthew Kobeszko, Greta Josephson, William Cotts, Sunil Pauwaa, Antone Tatooles, Imad Elkhatib, Rogelio Silva University of Illinois at Chicago – Advocate Christ Medical Center, IL

B02: FTY720 S-PHOSPHONATE SIGNIFICANTLY INHIBITS MRSA INDUCED PERMEABILITY, INFLAMMATION AND EPIGENETIC CHANGES IN LUNG ENDOTHELIUMLichun Wang, Steven M. Dudek University of Illinois at Chicago, IL

B03: ROLE OF LYSOCARDIOLIPIN ACYLTRANSFERASE IN LUNG EPITHELIAL CELL APOPTOSIS INDUCED BY CIGARETTE SMOKE EXTRACTMounica Bandela, Rama Kamesh Bikkavilli, Panfeng Fu, Vidyani Suryadevara, Sugasini Dhavamani, Subbaiah Papasani, Sunit Singla, Sekhar P. Reddy, Steven M. Dudek, Viswanathan Natarajan The University of Illinois at Chicago, IL

B04: DECREASED CONSUMPTION OF BRANCHED-CHAIN AMINO ACIDS PROMOTES LIFESPAN AND HEALTHSPAN IN WILD-TYPE AND PROGEROID MICENicole E. Cummings, Elizabeth N. Konon, Alexis T. Mitchell, Colin Boyle, Soha Ahmad, Allison C. Rodgers, Abigail Radcliff, Elizabeth M. Williams, Timothy Hacker, Dudley W. Lamming University of Wisconsin – Madison, WI

B05: CATHARTOCYTOSIS, A NOVEL CELLULAR PROCESS ESSENTIAL FOR METAPLASTIC DEDIFFERENTIATIONJeffrey W. Brown, Koushik K. Das, Spencer G. Willet, Megan D. Radyk, Joseph Burclaff, Jason C. Mills Washington University School of Medicine, MO

B06: SHORT-TERM METHIONINE DEPRIVATION IMPROVES METABOLIC HEALTH AND INDUCES PERSISTENT EPIGENETIC CHANGESShany E. Yang, Deyang Yu, Spencer A. Haws, Blake R. Miller, Jay L. Tomasiewicz, Matthew H. Wakai, Victoria Flores, Vincent L. Cryns, John M. Denu, Dudley W. Lamming University of Wisconsin – Madison, WI

B07: INHIBITION OF GROUP V PHOSPHOLIPASE A2 (GVPLA2) PROTECTS LUNG ENDOTHELIUM FROM METHICILLIN-RESISTANT STAPH AUREUS (MRSA) INDUCED PERMEABILITYYu M. Htwe, Lucille Meliton, Steven Dudek University of Illinois at Chicago, IL

B08: PRIMARY HUMAN AIRWAY AND ALVEOLAR RESIDENT PHAGOYTES ARE RESISTANT TO ANTHRAX LETHAL TOXINVineet I. Patel, J. Leland Booth, Elizabeth S. Duggan, Jordan P. Metcalf University of Oklahoma Health Sciences Center, OK

B09: MEASUREMENT-TO-MEASUREMENT BLOOD PRESSURE VARIABILITY AS AN INDEPENDENT PREDICTOR OF CARDIOVASCULAR DISEASE OUTCOMESAayush Visaria Rutgers University, NJ

ABSTRACT POSTER TITLES & AUTHORS


ABSTRACT POSTER TITLES & AUTHORSFriday, April 5th continued

B10: FULMINANT GIANT CELL MYOCARDITIS: A CASE OF EARLY DIAGNOSIS AND PROMPT TREATMENT RESULTING IN GOOD OUTCOMENajia Waheed1, Omer Iftikhar2, Robert Gordon3 1Rawalpindi Medical University; 2University of Chicago – Northshore, IL; 3University of Chicago – Northshore

B11: LOSS OF MYOSIN BINDING PROTEIN H-LIKE CAUSES CARDIAC CONDUCTION SYSTEM DYSFUNCTIONDavid Y. Barefield1, Sean Yamakawa1, Jordan Sell1, Michael Broman2, Brigitte Laforest2, Megan Puckelwartz1, Lisa Wilsbacher1, J. Andrew Wasserstrom1, Elizabeth McNally1 1Northwestern University, IL; 2University of Chicago, IL

B12: MANIPULATING POTASSIUM CHANNEL SUBDOMAINS TO PREVENT CARDIAC ARRHYTHMIADavid K. Jones1, Aliyah Keval2, Gail A. Robertson2 1University of Michigan, MI; 2University of Wisconsin – Madison, WI

B13: REGULATION OF MITOCHONDRIAL CALCIUM UPTAKE VIA TYROSINE PHOSPHORYLATION OF MITOCHONDRIAL CALCIUM UNIPORTERYuta Suzuki1, Jessica L. Cao2, Stephanie M. Adaniya2, Michael W. Cypress1, Bong Sook Jhun1, Jin O-Uchi1 1University of Minnesota, MN; 2Brown University, MN

B14: IN SITU LYMPHOCYTE AND DENDRITIC CELL CHARACTERIZATION IN IDIOPATHIC INFLAMMATORY MYOPATHIESIazsmin Bauer Ventura, Daniel Reilley, Peter Pytel, Vladimir Liarski University of Chicago, IL

B15: CAN SMARTPHONE-BASED PULSE OXIMETERS BE USED FOR MONITORING PATIENTS WITH CHRONIC PULMONARY DISEASE?Christie Ann Brillante, Julia Luo, Ashley Binder, Valentin Prieto-Centurion University of Illinois at Chicago, IL

B16: STREPTOCOCCUS SALIVARIUS BACTEREMIA LEADING TO THE DISCOVERY OF ENDOMETRIAL CARCINOMA:Shalini Chiravuri, Rai Dilawar Shah Jahan Conemaugh Memorial Medical Center, PA

B17: BIOINFORMATICS IDENTIFY ELMO1 AND APOA1 AS CANDIDATE GENES FOR SICKLE CELL-MEDIATED KIDNEY DISEASESantosh Saraf1, Xu Zhang1, Binal Shah1, Rasha Raslan1, Ellen Barry1, Bamidele Tayo2, James Lash1, Nora Franceschini3, Victor Gordeuk1 1University of Illinois at Chicago, IL; 2Loyola University, IL; 3University of North Carolina, NC

B18: REDUCED FOXO1 SIGNALING ATTENUATES NEGATIVE SIDE EFFECTS OF MTORC2 INHIBITIONSabrina N. Dumas, Dudley W. Lamming University of Wisconsin – Madison, WI

B19: PROTEIN S-DEPENDENT AND -INDEPENDENT FACTORS CONTRIBUTE TO THE INCREASED THROMBIN GENERATION IN HIV PATIENTSJeremy P. Wood, Meenakshi Banerjee, Thein Myint, Sidney W. Whiteheart University of Kentucky, KY

B20: A UNIQUE CASE OF CRYPTOCOCCUS AND HISTOPLASMOSIS CO-INFECTION IN AN HIV-NEGATIVE MALE ON CHRONIC STEROID THERAPYSamia Asif, Joseph Bennett, Rebecca Pauly University of Missouri – Kansas City, MO



B21: EXPRESSION OF THE INTEGRIN ALPHA6 BETA4 IN SEROUS OVARIAN NEOPLASMSRachel L. Stewart, Dava W. Piecoro, Teresa Knifley, Kathleen L. O’Connor University of Kentucky, KY

B22: UTILITY OF CARDIAC MRI IN THE PROGNOSTICATION OF PERIPARTUM CARDIOMYOPATHYJulien Feghaly, James Ampadu, Ariana Mooradian, Elsayed Abo Salem St. Louis University Hospital, MO

B23: DAILY PHYSICAL ACTIVITY IN PATIENTS WITH COPD AFTER HOSPITAL DISCHARGE IN AN UNDERSERVED POPULATIONValentin Prieto-Centurion1, Richard Casaburi2, David B. Coultas3, Mayank M. Kansal1, Spyros Kitsiou1, Julia J. Luo1, Jun Ma1, Cynthia S. Rand4, Ai-Yui M. Tan1, Jerry A. Krishnan1 1University of Illinois at Chicago, IL; 2Los Angeles BioMed Research Institute, CA; 3VA Portland Health Care System, OR; 4Johns Hopkins University, MD

B24: MYOSIN LIGHT CHAIN KINASE GENETIC VARIATION AND THE RISK OF PRECAPILLARY PULMONARY HYPERTENSION IN SICKLE CELL DISEASEDustin R. Fraidenburg1, Ken Batai2, Taimur Abbasi1, Joe G. N. Garcia2, Mark Gladwin3, Victor Gordeuk1, Rick Kittles2, Roberto F. Machado4 1University of Illinois at Chicago, IL; 2University of Arizona, AZ; 3University of Pittsburgh, PA; 4Indiana University, IN

B25: PARAOXANASE 1 DELETION LEADS TO INCREASED CARDIAC REMODELING AND CARDIAC FIBROSIS IN A DAHL SALT-SENSITIVE RAT MODEL OF CHRONIC KIDNEY DISEASEPrabhatchandra Dube, Fatimah K. Khalaf, Chrysan Mohammed, Armelle DeRiso, Dhanushya Battepatti, Tiana Sarsour, Iman Tassavvor, Steven Haller, Eric Morgan, David Kennedy University of Toledo, OH

B26: CAN VOLUME CALCULATIONS OF EN BLOCK RENAL TRANSPLANTS PREDICT RENAL FUNCTION?Martha G Menchacha, Keira Tulla, Manpreet Samra, Ivo Tzvetanov, Suman Setty University of Illinois, IL

B27: REAL-TIME CHARACTERIZATION OF INFLAMMATORY LUNG INJURYPatrick Belvitch1, Weiguo Chen1, Lucille Meliton1, Huashan Wang1, Joe JN. Garcia2, Jacobson Jeffrey1, Steve Dudek1 1University of Illinois at Chicago, IL; 2University of Arizona, AZ

B28: DOUBLE RULE IN: CONCOMITANT ACUTE CORONARY OCCLUSION AND PULMONARY EMBOLIZATIONPratik S. Velangi, Prabjot S. Nijjar University of Minnesota Medical School, MN

B29: CHARACTERISTICS OF PATIENTS DIAGNOSED WITH CATASTROPHIC CUTANEOUS CARCINOMATOSISNicole Bolick, Greg Kearney, Charles Phillips, Rebecca Shanesmith, Paul Vos

The Brody School of Medicine at East Carolina University, NC

B30: AQUAPORINS AND REACTIVE OXYGEN SPECIES IN INFLAMMATORY BREAST CANCERAnand Saripalli, Salah D. Dajani, Miroslava Repak, Neelam Sharma-Walia Rosalind Franklin University, IL

B31: LOW BRANCHED-CHAIN AMINO ACID DIET IN MEN WITH PREDIABETES AND OBESITYRowan Karaman, Dawn Davis, Dudley Lamming University of Wisconsin – Madison, WI

B32: GREATER PLAINS COLLABORATIVE (GPC): BURDEN OF IMAGING RENAL CYSTSMohamad A. Kalot1, Nedaa Husainat1, Mohammed Al Khatib1, Kathleen Wilkinson2, Lama Noureddine3, Lindsay Cowell2, Philipp Dahm4, Reem Mustafa1 1University of Kansas Medical Center, KS; 2University of Texas Southwestern Medical Center, TX; 3University of Iowa, IA; 4University of Minnesota Medical Center, MN



B33: EVALUATING THE EFFECT OF TUMOR NECROSIS ON GLYCOLYTIC FLUX AND CELL SURVIVAL IN GLIOBLASTOMAEvan Noch, Isaiah Yim, Lewis Cantley Weill Cornell Medicine, NY

B34: AORTOENTERIC FISTULA WITH DUODENAL GRAFT MATERIAL MIGRATION RESULTING IN GASTROINTESTINAL BLEEDINGLaith Numan1, Mohamad Kalot2, Nedaa M. Husainat2, Omar Abughanimeh1 1University of Missouri – Kansas City, MO; 2University of Kansas Medical Center, KS

B35: CARDIOPROTECTIVE EFFECTS OF PARAOXANASE 3 IN A DAHL SALT-SENSITIVE RAT MODEL OF CHRONIC KIDNEY DISEASEPrabhatchandra Dube, Chrysan Mohammed, Fatimah Khalaf, Armelle DeRiso, Iman Tassavvor, Dhanushya Battepatti, Tiana Sarsour, Steven Haller, Eric Morgan, David J. Kennedy University of Toledo, OH

B36: PREVALENCE AND MARKERS OF CORONARY CALCIUM ON CANCER COMPUTED TOMOGRAPHY SCANS IN PATIENTS AT RISK FOR CARDIOVASCULAR DISEASE AFTER POTENTIALLY CARDIOTOXIC CANCER TREATMENTMatthew C. Hooks, Prabhjot S. Nijjar, Ko-Hsuan Chen, Michelle Wang, Milkeesso Foge, Ryan Cullen, Tejaswini Maganti, Anne Blaes, Chetan Shenoy University of Minnesota, MN

B37: EXPLORING BARRIERS TO AND FACILITATORS OF UPTAKE OF EVIDENCE-BASED TREATMENT FOR FAMILIAL HYPERCHOLESTEROLEMIA: PATIENT PERSPECTIVESLaney K. Jones, Alanna Kulchak Rahm, Terry L. Seaton, Christina Gregor, Amy C. Sturm, Marc S. Williams Geisinger, PA

B38: HYPOTHENAR HAMMER SYNDOME: AN OVERLOOKED OCCUPATIONAL VASCULAR PATHOLOGYNajia Waheed1, Omer Iftikhar2, Kambiz Zorriasateyn3 1Rawalpindi Medical University; 2University of Chicago – Northshore, IL; 3University of Chicago – Northshore

B39: A RARE CASE OF ANOMALOUS CORONARY ARTERY ORIGINATING FROM THE OPPOSITE SINUS, A DEADLY LESION OR A BENIGN FINDINGSenan Yasar, Abdallah Mansour, Tushar Tarun, Mary Dohrmann University of Missouri – Columbia, MO

B40: CHRONIC ACTIVE EPSTEIN-BARR VIRUS-INDUCED HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSISSiroj Dejhansathit, Attaya Suvannasankha Indiana University School of Medicine, IN

B41: A RARE CASE OF A RAOULTELLA SPECIES BACTEREMIA IN A NEONATEAlexandra Iacob, Rebecca Meyer Miller Children’s & Women’s Hospital Long Beach, CA

B42: PELIOSIS HEPATIS AND COMMON VARIABLE IMMUNODEFICIENCYSydney Joyner, Evelyn Angulo, Sharmilee Nyenhuis University of Illinois at Chicago, IL

B43: CHARACTERIZING FATIGABILITY IN HOSPITALIZED PATIENTS WITH ANEMIACyrus Alavi, Micah Prochaska, Sarah Bradbury University of Chicago, IL




Poster Session C

C01: OVEREXPRESSION OF LONG NON-CODING RNA H19 REGULATED THE METHIONINE METABOLISM IN ALCOHOLIC LIVER DISEASEZhihong Yang, Praveen Kusumanchi, Suthat Liangpunsakul Department of Medicine, Indiana University, IN

C02: ABLATING ADIPOSE CREB3L3 PRESERVES METABOLIC HEALTH DURING OBESITYMaximilian McCann1, Guifen Qiang1, Shengxian Li1, Yanliang Li1, Victoria Gil1, Kezhong Zhang2, Chong Wee Liew1

1University of Illinois at Chicago, IL; 2Wayne State University, MI

C03: TARGETED DISRUPTION OF NA/K-ATPASE – SRC SIGNALING CASCADE SIGNIFICANTLY REDUCES RENAL INFLAMMATION AND OXIDATIVE STRESS FOLLOWING 5/6TH PARTIAL NEPHRECTOMYFatimah K. Khalaf1, Prabhatchandra Dube1, Andrew Kleinhenz1, Deepak Malhotra1, Amira Gohara1, Christopher Drummond1, Jiang Tian1, Steven Haller1, Zijian Xie2, David Kennedy1 1University of Toledo, OH; 2Marshall University, WV

C04: ALGINATE OLIGOSACCHARIDE ALLEVIATES D-GLACTOSE-INDUCED CARDIAC AGING IN MICE VIA REGULATING THE SIRT1/PGC-1A SIGNALING PATHWAYWenjing Feng1, Jianya Liu2, Jie Mou2, Meiping Feng2, Shan Wang2, Huashi Guan3, Yongjun Mao2 1The Affiliated Hospital of Qingdao University, The School of Public Health of Qingdao University; 2The Affiliated Hospital of Qingdao University; 3School of Medicine and Pharmacy, Ocean University of China

C05: Gq-MEDIATED PKD ACTIVATION INDUCES ABERRANT MITOCHONDRIAL FISSION THROUGH PHOSPHORYLATION OF DLP1 IN CARDIOMYOCYTESBong Sook Jhun1, Stephanie M. Adaniya2, Michael W. Cypress1, Yuta Suzuki1, Ulrike Mende2, Gaurav Choudhary3 1Lillehei Heart Institute, Cardiovascular Division, Department of Medicine, University of Minnesota, MN; 2Cardiovascular Research Center, Cardiovascular Institute, Rhode Island Hospital and The Alpert Medical School of Brown University, Providence, RI;

3Vascular Research Laboratory, Providence Veterans Affairs Medical Center and The Alpert Medical School of Brown University, Providence, RI

C06: ENDOTHELIAL CELL INTEGRIN BETA4 KNOCKOUT ATTENUATES LPS-INDUCED MURINE ACUTE LUNG INJURYWeiguo Chen1, Patrick Belvitch1, Anne Cress2, Viswanathan Natarajan V1, Jeffrey Jacobson1 1University of Illinois at Chicago, IL; 2University of Arizona, AZ

C07: AUTOPHAGY FACILITATES MITOCHONDRIAL BIOGENESIS TO MAINTAIN MITOCHONDRIAL HOMEOSTASIS DURING CARDIAC ISCHEMIA/REPERFUSION INJURY Jing Yang, Jin He, Scott Ballinger, Martin E. Young, Sumanth D. Prabhu, Glenn Rowe, Jianyi Zhang, Min Xie University of Alabama at Birmingham, AL

C08: ROLE OF UCHL1 IN RADIATION-INDUCED LUNG INJURY MEDIATED BY SPHINGOLIPIDSYulia Epshtein, Huashan Wang, Jeffrey R. Jacobson University of Illinois at Chicago, IL

C09: DISRUPTED INFLAMMASOME ACTIVATION BY THE VASCULAR ECTO-APYRASE CD39 IN VENOUS THROMBOSISVinita Yadav, Liguo Chi, Raymond Zhao, Benjamin Jacobs, Hui Liao, Michael Holinstat, Jason S. Knight, David J. Pinsky, Yogendra Kanthi University of Michigan, MI

C10: APPROPRIATE USE OF TELEMETRY: INDICATION VERSUS GRATIFICATIONJulien Feghaly, Zachary Oman, Ariana Mooradian St. Louis University Hospital, MO



C11: APICAL HYPERTROPHIC CARDIOMYOPATHY: A DIAGNOSTIC DILEMMANajia Waheed1, Rizwan A. Khan2, Omer Iftikhar3, David M. Najman3 1Rawalpindi Medical University, IL; 2St. Elizabeth Medical Center, MA; 3University of Chicago – Northshore, IL

C12: INCEDENTAL DIAGNOSIS OF CARDIAC AMLOIDOSIS IN AN 86-YEAR OLD WITH MGUS – AL OR ATTR?Pratik S Velangi, Chetan Shenoy University of Minnesota, MN

C13: CHRYSEOBACTERIUM INDOLOGENES BACTEREMIA IN CIRRHOSISJaspreet S. Suri, Rajab Idriss, Ahmed Al-Khazraji, Raza Malik Beth Israel Deaconess Medical Center, MA

C14: A RARE CASE OF INFECTIOUS PSEUDOANEURYSM DUE TO ASPERGILLUS FLAVUS IN THE SETTING OF RENAL TRANSPLANTSamia Asif, Joseph Bennett, Rebecca Pauly University of Missouri – Kansas City, MO

C15: ALTERNATIVE APPROACH TO TREAT LINEZOLID INDUCED LACTIC ACIDOSIS IN ALCOHOLIC PATIENTYi Xiong1, Victor Kim1, Ehsan Owrangi2, arshdeep Tindni1, Ngozi Nwankwo3 1Mercy Health Jewish Hospital, OH; 2Saba University School of Medicine; 3University of Cincinnati, OH

C16: RAPID PROGRESSION OF SEVERE ACUTE PYELONEPHRITIS TO XANTHOGRANULOMATOUS PYELONEPHRITISShalini Chiravuri, Mohammed Saad Eldin Conemaugh Memorial Medical Center, PA

C17: CURBING LIPIDS: IMPACTS ON BREAST CANCERAnika Dutta Chicago Medical School, IL

C18: A RARE CASE OF SERRATIA ENDOCARDITIS IN A PATIENT WITH CHRONIC MYELOID LEUKEMIAAnnapoorna Singh1, Daulath Singh2 1UMKC School of Medicine, MO; 2Loyola University Medical Center, IL

C19: DISULFIRAM HEPATITIS: A MAJOR CONCERN IN ALCOHOL WITHDRAWAL CAREJaspreet S. Suri, Ahmed Al-Khazraji, Rajab Idriss, Raza Malik Beth Israel Deaconess Medical Center, MA

C20: PROXIMAL WEAKNESS, PAIN, AND CACHEXIA: A CASE OF DIABETIC AMYOTROPHYMatthew J. Mandell1, Dana Mourad2, Leen Alkhouli1, Erin Drever1 1University of Illinois at Chicago/Advocate Christ Medical Center, IL; 2Chicago Medical School at Rosalind Franklin University of Medicine and Science, IL

C21: THE ROLE OF NUCLEOLIN IN CELLULAR SIGNALING PATHWAYS FOR PROLIFERATION OF INFLAMMATORY BREAST CANCER (IBC)Sandra Campos Rosalind Franklin University of Medicine and Science, IL

C22: DIAGNOSTIC APPROACH TO ACUTE RHEUMATIC FEVER PRESENTING AS POLYARTHRITISJulien Feghaly, Ariana Mooradian St. Louis University Hospital, MO



C23: EVALUATION OF A COMMUNITY WELLNESS WORKER PILOT PROGRAM FOR LATINO MOTHERS AND INFANTSNatalie Guerrero1, Alissa Small1, Carmen Valdez2, Mariela Quesada Centeno3, Sarah Webber1 1University of Wisconsin School of Medicine and Public Health, WI; 2University of Texas at Austin, TX; 3Centro Hispano, WI

C24: THE ASSOCIATION BETWEEN PHARMACIST EMPLOYMENT LEVELS AND RECEIPT OF INFLUENZA VACCINESUriel Kim1, Noel Kim2 1Case Western Reserve University, OH; 2Community Hospital of the Monterey Peninsula, CA

C25: GASTRIC OUTLET OBSTRUCTION IN CROHN’S DISEASE (CD): A CASE REPORT AND LITERATURE REVIEWJaspreet S. Suri, Ahmed Al-Khazraji, Raza Malik Beth Israel Deaconess Medical Center, MA

C26: THE EFFECTS OF NON-CONTACT BOXING ON NON-MOTOR FUNCTIONS OF PARKINSON’S DISEASE – A PILOT STUDYAshwath Sampath, Raghav Govindarajan University of Missouri School of Medicine, MO

C27: PROTECTIVE EFFECT OF DIETARY FIBER INTAKE ON INFLAMMATION AND RESPIRATORY MORBIDITY IN THE ADULT NHANES POPULATION (2007 – 2012)Muhammad A. Saeed, Alam Morshed, Elizabeth Lyden, Corrine K. Hanson, Tricia D. LeVan University of Nebraska Medical Center, NE

C28: ACROANGIODERMATITIS OF MALI IN THE SETTING OF SICKLE CELL DISEASEBalaji Jothishankar, Haider Bangash, Farah Abdulla University of Chicago, IL

C29: SERUM PROTEOMIC ANALYSIS IN THORACIC SURGERY PATIENTS WITH DELIRIUM:Sikandar H. Khan, Russell Purpura, Dmitriy Golovyan, Babar Khan Indiana University School of Medicine

C30: THE EFFECT OF RED BLOOD CELL TRANSFUSION ON FATIGABILITY IN HOSPITALIZED PATIENTS WITH ANEMIAMicah Prochaska, Rilwan Babajide, Sarah Bradbury, Daniel Jesuthasen, David Meltzer University of Chicago Pritzker School of Medicine, IL

C31: HEPATOCELLULAR CARCINOMA WITH TUMOR THROMBUS EXTENDING FROM THE PORTAL VEIN TO THE RIGHT ATRIUMLaith Numan1, Mohamad Kalot2, Nedaa M. Husainat1, Omar Abughanimeh1 1University of Missouri – Kansas City, MO; 2University of Kansas Medical Center, KS

C32: PYELONEPHRITIS: A CLINICAL OR RADIOGRAPHIC DIAGNOSIS?Ariana Mooradian, Samantha Gammon, Shannon Burke Saint Louis University, MO

C33: ASSOCIATION BETWEEN CREST SYNDROME AND ACUTE DIABETES MELLITUS TYPE ONE; CASE REPORT IN AN ELDERLY PATIENTAhmad M. Sharayah Monmouth Medical Center, NJ

C34: INITIALLY MISDIAGNOSED HEPATOCELLULAR CARCINOMA WITH BRAIN METASTASISAriana Mooradian, Mudresh Mehta, Samantha Gammon Saint Louis University, MO



C35: PATTERNS OF TOBACCO CONSUMPTION AMONG HIGH-RISK POPULATION OF BANGLADESHMobashera Jahan1, Mostafizur Rahman1, Khadija Leena1, Syeda H. Afroze2, Gias U. Ahsan1, Mohammad N. Uddin3

1North South University Global Health Institute; 2Texas A&M Health Science Center College of Medicine, TX; 3Orion Institute for Translational Medicine, TX

C36: TOO MUCH OF A GOOD THING IS NOT GOOD: A CASE OF COLD AGGLUTININ AUTOIMMUNE HEMOLYTIC ANEMIAJoshua Gordon, Narendranath Epperla Ohio State University, OH

C37: DIFFUSE LARGE B-CELL LYMPHOMA PRESENTING AS A PANCREATIC MASS: AN UNUSUAL PRESENTATIONYousaf Zafar1, Anahat Kaur1, Adnan Zafar2, Arsalan Zafar3 1University of Missouri at Kansas City, MO; 2CMH Lahore Medical College; 3FMH College of Medicine

C38: VALIDATION AND REFINEMENT OF THE 2017 AHA/ACC/HRS GUIDELINE RECOMMENDATIONS FOR USE OF IMPLANTABLE CARDIOVERTER DEFIBRILLATORS IN CARDIAC SARCOIDOSISFelipe Kazmirczak, Ko-Hsuan Chen, Selcuk Adabag, Lisa Von Wald, Henri Roukoz, Osama Okasha, Afshin Farzaneh-Far, Prabhjot S. Nijjar, Mehmet Akcakaya, Chetan Shenoy University of Minnesota, MN

C39: USING CMS DATA TO PROJECT ECONOMIC BURDEN OF ANTINEOPLASTIC DRUGS IN THE UNITED STATESKeith D. Huff1, Eric N. Huff2, Kayla Link2, Eric Kruep3 1Butler University, College of Pharmacy and Health Sciences, IN; 2Southern Illinois University Edwardsville College of Pharmacy, IL;

3Kruep Outcomes Research Technology, FL

C40: ADENOCARCINOMA FOLLOWING TREATMENT OF LYMPHOMA: DOES RITUXIMAB INCREASE RISK OF SECONDARY MALIGNANCY?Ariana Mooradian, Julien Feghaly Saint Louis University, MO

C41: A CASE OF NEGLECTED SQUAMOUS CELL CARCINOMA OF THE SKINNedaa M. Husainat1, Mohamad Kalot1, Aref Qureini2, Laith Numan2 1University of Kansas Medical Center, KS; 2University of Missouri – Kansas City, MO

C42: THE DEVIL IS IN THE DETAILS: A CASE OF DRUG INDUCED AGRANULOCYTOSISJoshua Gordon, Narendranath Epperla Ohio State University, OH

C43: NUCLEOLIN’ ROLE IN ANGIOGENESIS/LYMPHANGIOGENESIS IN INFLAMMATORY BREAST CANCER (IBC)Samantha Russell, Mira Repak, Neelam Sharma-Walia Rosalind Franklin University, IL

C44: A RARE CASE OF CLEAR CELL CARCINOMA PRESENTING AS VARIANT ANGINANikhil Malhotra, Ihab Hassanieh, Ghassan Daher, Michael Lim Saint Louis University, MO

C45: DESSEMINATED NOCARDIOSIS IN AN IMMUNOCOMPETENT HOST: A CASE REPORTYousaf Zafar1, Harris Zamir1, Adnan Zafar2, Arsalan Zafar3 1University of Missouri – Kansas City, MO; 2CMH Lahore Medical College; 3FMH College of Medicine

C46: A COMPARISON BETWEEN INTRA-OPERATIVE ANGIOGRAPHIC COMPLICATIONS OF ORBITAL AND ROTATIONAL CORONARY ATHERECTOMY USED IN PATIENTS WITH CORONARY ARTERY DISEASEAbdallah Mansour1, Haytham Allaham1, Fares Alahdab2, Marcus Theimann1, Fadi Ghrair1, Kul Aggarwal1, Obai Abdullah1 1University of Missouri – Columbia, MO; 2Mayo Clinic, FL


AUTHOR INDEX

Abbasi, Taimur B24

Abdi, Abdullahi A03

Abdulla, Farah C28

Abdullah, Obai C46

Abo Salem, Elsayed B22

Abughanimeh, Omar B34, C31

Abumoawad, Abdelrhman A35

Adabag, Selcuk C38

Adaniya, Stephanie A20, A28, B13, C05

Adrian, Alexis A36

Afroze, Syeda A39, C35

Aggarwal, Kul C46

Ahmad, Soha B04

Ahsan, Gias C35

Akcakaya, Mehmet A38, C38

Al Khatib, Mohammed B32

Al-Khazraji, Ahmed C13, C19, C25

Alahdab, Fares C46

Alavi, Cyrus B43

Alkhouli, Leen C20

Allaham, Haytham C46

Alreefi, Hajar A25

Ampadu, James B22

Angulo, Evelyn B42

Anis, Mariam A11

Arora, Vineet A09

Asif, Samia B20, C14

Babajide, Rilwan C30

Baer, Alan A40

Baig, Noman A11

Balaji, Aakash A03

Baliu-Rodriguez, David A32

Ballinger, Scott C07

Bandela, Mounica B03

Banerjee, Avik A17

Banerjee, Meenakshi B19

Bangash, Haider C28

Barefield, David B11

Barish, Grant A37

Barnes, Melissa A15

Barry, Ellen B17

Batai, Ken B24

Bateman, Randall A06

Bathgate, Ross A39

Batra, Surider A13

Battepatti, Dhanushya B25, A35

Bauer Ventura, Iazsmin B14

Baur, Joseph A04

Belvitch, Patrick B27, C06

Bennett, Joseph B20, C14

Bethel, Christopher A15

Bhavani, Siva A22

Bikkavilli, Rama Kamesh B03

Binder, Ashley B15

Blaes, Anne B36

Bolick, Nicole B29

Bonomo, Robert A15

Booth, J. Leland B08

Boyle, Colin B04

Bradbury, Sarah B43, C30

Breidenbach, Joshua A32

Brillante, Christie Ann B15

Brindise, Elizabeth A02

Brinkman, Jacqueline A26

Brody, Steve A27

Broman, Michael B11

Brown, Jeffrey B05

Burclaff, Joseph B05

Burke, Shannon C32

Bustamante, Angela A07

Campos, Sandra C21

Cantley, Lewis B33

Cao, Jessica B13

Carey, Kyle A09, A22

Carruthers, Nicholus A32

Casaburi, Richard B23

Casey, Carol A10

Chapagain, Udita A24, A34

Chebib, Fouad A25, A36

Chen, Ko-Hsuan B36, C38

Chen, Rong A01

Chen, Weiguo B27, C06

Chi, Liguo C09

Chiravuri, Shalini B16, C16


AUTHOR INDEX

Choudhary, Gaurav A28, C05

Churpek, Matthew A09, A22

Ciesielski, Mark A19

Clements, Richard A28

Coates, Bria A19

Collins, Michael A14

Conley, Jason A01

Conley, Sabena A35

Cordoba-Chacon, Jose A16

Cotts, William A31, B01

Coultas, David B23

Cowell, Lindsay B32

Crane, Paul A07

Cress, Anne C06

Cryns, Vincent B06

Cullen, Ryan B36

Cummings, Nicole A04, A18, A26, A42, B04

Cypress, Michael A20, A28, B13, C05

Daher, Ghassan C44

Dahm, Philipp B32

Dajani, Salah B30

Darabi, Houshang A33

Das, Koushik B05

Davis, Dawn B31

Day, Gregory A06

Dejhansathit, Siroj B40

Denu, John B06

DeRiso, Armelle B25, B35

Dhavamani, Sugasini B03

Dickinson, John A27

Dohrmann, Mary B39

Dousa, Khalid A15

Drever, Erin C20

Drummond, Christopher C03

Dube, Prabhatchandra B25, B35, C03

Dudek, Steve B27

Dudek, Steven B02, B07

Duggan, Elizabeth B08

Dumas, Sabrina A18, B18

Dutta, Anika C17

Edelson, Dana A09

Eid, Albert A43

Eid, Maya A21

Eirin, Alfonso A25, A36

El Atrouni, Wissam A43

Elkhatib, Imad A31, B01

Engelking, Luke A30

Epperla, Narendranath C36, C42

Epshtein, Yulia C08

Fang, Yun A08

Farzaneh-Far, Afshin A38, C38

Feghaly, Julien B22, C10, C22, C40

Feng, Meiping C04

Feng, Wenjing C04

Flores, Victoria A04, A18, A42, B06

Foge, Milkeesso B36

Fraidenburg, Dustin A11, B24

Franceschini, Nora B17

Fu, Panfeng B03

Futtner, Christopher A37

Gammon, Samantha C32, C34

Gaponenko, Vadim A17

Garcia, Joe B24, B27

Ghrair, Fadi C46

Gil, Victoria C02

Gladwin, Mark B24

Gohara, Amira C03

Golovyan, Dmitriy C29

Gordeuk, Victor B17, B24

Gordon, Joshua C36, C42

Gordon, Robert B10

Govindarajan, Raghav C26

Green, Cara A18, A26

Greenberg, Jared A22

Gregor, Christina B37

Guan, Huashi C04

Guerrero, Natalie C23

Gupta, Kalpna A05

Hacker, Timothy B04

Haller, Steven A29, A32, B25, B35, C03

Halstrom, Rachel A11

Hammock, Bruce A41

Hanson, Corrine C27

Harris, Peter A25, A36


AUTHOR INDEX

Harrison, Devin A08

Hassanieh, Ihab C44

Haws, Spencer B06

He, Jin C07

Hesse, Steven A12

Hickson, LaTonya A35

Hitchinson, Ben A17

Holinstat, Michael C09

Hooks, Matthew B36

Hossain, Mohammed A39

Htwe, Yu B07

Huff, Eric C39

Huff, Keith C39

Hughes, Andrew A38

Husainat, Nedaa B32, B34, C31, C41

Hwang, Sung A41

Iacob, Alexandra B41

Idriss, Rajab C13, C19

Iftikhar, Omer B10, B38, C11

Imig, John A41

Irazabal, Maria V. A25, A36

Isailovic, Dragan A32

Jacobs, Benjamin C09

Jacobs, Michael A15

Jacobson, Jeffrey A11, C06, C08

Jahan, Mobashera C35

Jang, Cholsoon A04

Jeffrey, Jacobson B27

Jesuthasen, Daniel C30

Jhun, Bong Sook A20, A28, B13, C05

Jones, David B12

Jones, Laney B37

Jordan, Kyra A35

Josephson, Greta A31, B01

Jothishankar, Balaji C28

Joyner, Sydney B42

Kaja, Simon A14

Kalinowski, Michael A02, A31, B01

Kalot, Mohamad A43, B32, B34, C31, C41

Kanchan, Ranjana A13

Kansal, Mayank B23

Kanthi, Yogendra C09

Karaman, Rowan B31

Kaur, Anahat C37

Kazmirczak, Felipe A38, C38

Kearney, Greg B29

Keene, C. Dirk A07

Kennedy, David A29, A32, B25, B35, C03

Keval, Aliyah B12

Khalaf, Fatimah B35, C03

Khalaf, Fatimah K B25

Khan, Babar C29

Khan, Md Abdul A41

Khan, Rizwan C11

Khan, Sikandar C29

Kharbanda, Kusum A10

Kilaru, Megha A09

Kim, Hee-Yong A14

Kim, Noel C24

Kim, Seo Rin A35

Kim, Uriel C24

Kim, Victor C15

Kirkland, James A35

Kitsiou, Spyros B23

Kittles, Rick B24

Kleinhenz, Andrew A29, C03

Knifley, Teresa B21

Knight, Jason C09

Knight, Kurt A10

Kobeszko, Matthew A02, A31, B01

Kociolek, Larry A03

Komarova, Yulia A17

Konon, Elizabeth B04

Kothari, Shana A02, A31, B01

Kouzoukas, Dimitrios A14

Kredell, Katherine A18

Kreiswirth, Barry A15

Krishnan, Jerry B23

Kruep, Eric C39

Kuehl, Thomas A39

Kulchak Rahm, Alanna B37

Kurz, Sebastian A15

Kusumanchi, Praveen C01

Lad, Apurva A29, A32


AUTHOR INDEX

Laforest, Brigitte B11

Lamming, Dudley A04, A18, A26, A42, B04, B06, B18, B31

Lash, James B17

Leena, Khadija C35

Lei, Jianxun A05

Lerman, Lilach A25, A35, A36

LeVan, Tricia C27

Li, Shengxian C02

Li, Yanliang C02

Liangpunsakul, Suthat C01

Liao, Hui C09

Liarski, Vladimir B14

Liew, Chong Wee C02

Lim, Michael C44

Link, Kayla C39

Liu, Jianya C04

Luo, Julia B15, B23

Lyden, Elizabeth C27

Lyons, Patrick A09

M Dudek, Steven B03

Ma, Jun B23

MacAvish, Tom A33

Machado, Roberto B24

Macura, Slobodan A25, A36

Maganti, Tejaswini B36

Mahapatra, Sidharth A13

Malecki, Kristen A04, A42

Malhotra, Deepak C03

Malhotra, Nikhil C44

Malik, Raza C13, C19, C25

Manchanda, Upasna A43

Mandell, Matthew C20

Mansour, Abdallah B39, C46

Mao, Yongjun C04

Martin, Cindy A38

Martin, Molly A33

McCann, Maximilian C02

Mccauley, Leslie A09

Mccoy, Sara A40

McNally, Elizabeth B11

Mehta, Mudresh C34

Meliton, Lucille B07, B27

Meltzer, David C30

Menchacha, Martha B26

Mende, Ulrike C05

Metcalf, Jordan B08

Meyer, Rebecca B41

Miller, Blake B06

Mills, Jason B05

Mitchell, Alexis B04

Mohammed, Chrysan B25, B35

Mooradian, Ariana B22, C10, C22, C32, C34, C40

Morgan, Eric B25, B35

Morshed, Alam C27

Mou, Jie C04

Mourad, Dana C20

Muratalla, Jose A16

Mustafa, Reem B32

Mutlu, Gokhan A08

Myint, Thein B19

Najman, David C11

Nasser, Mohd. Wasim A13

Natarajan, Viswanathan B03

Natarajan V, Viswanathan C06

Nigdelioglu, Recep A08

Nijjar, Prabhjot A38, B36, C38

Nijjar, Prabjot B28

Nikodemova, Maria A04, A42

Noch, Evan B33

Norris, Gregory A16

Noureddine, Lama B32

Numan, Laith B34, C31, C41

Nwankwo, Ngozi C15

Nyenhuis, Sharmilee B42

O’Connor, Kathleen B21

O-Uchi, Jin A20, A28, B13

Okasha, Osama A38, C38

Oman, Zachary C10

Omura, Yasuhiro A37

Opron, Kristopher A07

Owrangi, Ehsan C15

Ozer, Egon A03

P. Reddy, Sekhar B03

Pak, Heidi A18, A26


AUTHOR INDEX

Palagama, Dilrukshika A32

Pantho, Ahmed A39

Papasani, Subbaiah B03

Pappalardo, Andrea A33

Park, Eunhae A42

Patel, Vineet B08

Pauly, Rebecca B20, C14

Pauwaa, Sunil A31, B01

Perry, Deborah A13

Perumal, Naveen Kumar A13

Pervin, Najwa A24

Phillips, Charles B29

Picart, Jamila A09

Piecoro, Dava B21

Pins, Danielle A16

Pinsky, David C09

Prabhu, Sumanth C07

Prieto-Centurion, Valentin B15, B23

Prochaska, Micah B43, C30

Puckelwartz, Megan B11

Pulia, Michael A12

Purpura, Russell C29

Pytel, Peter B14

Qiang, Guifen C02

Qu, Xinyan A17

Quesada Centeno, Mariela C23

Qureini, Aref C41

Rabinowitz, Joshua A04

Radcliff, Abigail B04

Radyk, Megan B05

Rahman, Mostafizur C35

Ramachandran, Krithika A37

Rand, Cynthia B23

Rasineni, Karuna A10

Raslan, Rasha B17

Reilley, Daniel B14

Reilly, Austin A01

Ren, Hongxia A01

Repak, Mira C43

Repak, Miroslava B30

Ridge, Karen A19

Ridgway, Jessica A23

Robertson, Gail B12

Rodgers, Allison B04

Rojas, Juan A09

Roukoz, Henri C38

Rowe, Glenn C07

Russell, Samantha C43

Saad Eldin, Mohammed C16

Saeed, Muhammad C27

Sampath, Ashwath C26

Sampene, Emmanuel A40

Samra, Manpreet B26

Saraf, Santosh B17

Saripalli, Anand B30

Sarsour, Tiana B25, B35

Schmidt, Robert A06

Schneider, John A23

Schreiber, Jennifer A14

Schwei, Rebecca A12

Seaton, Terry B37

Sell, Jordan B11

Selvaraju, Suresh A15

Senagolage, Madhavi A37

Setty, Suman B26

Shah, Binal B17

Shah Jahan, Rai Dilawar B16

Shanesmith, Rebecca B29

Sharayah, Ahmad C33

Sharma-Walia, Neelam B30, C43

Shenoy, Chetan A38, B36, C12, C38

Sigurdson, Wendy A06

Silva, Rogelio A02, A31, B01

Singer, Benjamin A07

Singh, Annapoorna C18

Singh, Daulath C18

Singla, Sunit B03

Small, Alissa C23

Sommars, Meredith A37

Sperling, Anne A22

Spicer, Alexandra A04, A42

Standiford, Theodore A07

Stanford, Kimberly A23

Stemmer, Paul A32


AUTHOR INDEX

Stewart, Rachel B21

Stumpf, Monica A24, A34

Sturm, Amy B37

Su, Robin A29, A32

Sul, Christina A19

Sundareshan, Vidya A24, A34

Suri, Jaspreet C13, C19, C25

Suryadevara, Vidyani B03

Suvannasankha, Attaya B40

Suzuki, Yuta A20, A28, B13, C05

Sweeter, Jenea A27

Tajuddin, Nuzhath A14

Tan, Ai-Yui B23

Tang, Hui A35

Tarun, Tushar B39, C46

Tassavvor, Iman B25, B35

Tatooles, Antone A31, B01

Tayo, Bamidele B17

Tchkonia, Tamar A35

Thapa, Ishwor A13

Tian, Jiang C03

Tindni, arshdeep C15

Tomasiewicz, Jay A18, A26, A42, B06

Torres, Vicente A25, A36

Tug, Ali A36

Tulla, Keira B26

Turner, Margaret A19

Tzvetanov, Ivo B26

Uddin, Mohammad A39, C35

Valdez, Carmen C23

Velangi, Pratik A38, B28, C12

Venable, Laura A09

Verhoef, Philip A22

Visaria, Aayush B09

Von Wald, Lisa C38

Vos, Paul B29

Vuckovic, Ivan A25, A36

Waheed, Najia B10, B38, C11

Wakai, Matthew A26, B06

Wang, Huashan B27, C08

Wang, Lichun B02

Wang, Michelle B36

Wang, Shan C04

Wang, Ying A05

Wasserstrom, J. Andrew B11

Watkins, Lauren A06

Webber, Sarah C23

Whiteheart, Sidney B19

Wildburger, Norelle A06

Wilkinson, Kathleen B32

Willet, Spencer B05

Williams, Elizabeth B04

Williams, Marc B37

Wilsbacher, Lisa B11

Wood, Jeremy B19

Wu, David A08

Xie, Min C07

Xie, Zijian C03

Xiong, Yi C15

Yadav, Vinita C09

Yamakawa, Sean B11

Yan, Shijun A01

Yang, Jing C07

Yang, Shany A18, A26, A42, B06

Yang, Zhihong C01

Yasar, Senan B39

Yim, Isaiah B33

Young, Martin C07

Yu, Deyang A04, A18, A26, A42, B06

Zafar, Adnan C37, C45, C37, C45

Zafar, Yousaf C37, C45

Zamir, Harris C45

Zawieja, David A39

Zhang, Chongxu A17

Zhang, Jianyi C07

Zhang, Kezhong C02

Zhang, Song A25

Zhang, Xu B17

Zhao, Raymond C09

Zhao, Shuangping A17

Zhu, Xiang-Yang A35

Zorriasateyn, Kambiz B38


NOTES

Learn more atwww.csctr.org/early-career-development-award and upload your application for a chance of $10,000 for your research.

Eligibility Requirements• ECDA applicants must hold an MD, DO, MD/PhD, or PhD• PhD applicants must be conducting translational research within a clinical

department or hold an appointment in clinical department• Applications from candidates with a current K Award or equivalent (e.g. VA

Career Development Award, or American Heart Association SDG Award) are strongly encouraged

• Priority is given to candidates associated with institutions from the Central region of the United States.

CSCTR provides a $10,000 annual award to outstanding new investigators to supplement any combination of salary and/or lab support.

Up to six (6) ECDA grants are provided annually. Applicants are required to submit a brief research application, two letters of support, and a copy of their current curriculum vitae.

CENTRAL SOCIETY FOR CLINICAL AND TRANSLATIONAL RESEARCH

CSCT

R-03

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EARLY CAREER DEVELOPMENT AWARD

Application DeadlineOctober 18www.csctr.org

Central Society for Clinical and Translational Research555 East Wells StreetSuite 1100Milwaukee, WI 53202Phone (414) 273-2209Fax (414) [email protected]

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Twitter @CSCTR_Org

Midwestern Section American Federation for Medical Research500 Cummings Center, Ste 4400 Beverly, MA 01915 Phone (978) 927-8330 Fax (978) [email protected]

Twitter @AFMResearch

www.csctr.org/annual-meeting Like us on Facebook @CSCTR WWW.AFMR.ORG FOLLOW US ON TWITTER @AFMRESEARCH

CSC

TR-0

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Midwest Clinical& TranslationalResearch Meetingof Central Society for Clinical& Translational Research andMidwestern American Federationfor Medical Research

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