essenc i al therapy

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ZITHROMAX ® 200mg/5ml Oral suspension 10 mg/kg/d once daily SUPRAX ,SEFRAX ® SEFIXIME 1OO mg/5ml Oral suspension 8mg/kg/d % 1-2 Zinnat ® (cefuroxime): suspension 125mg/5ml,Tablet &sachets. Dose: 3mo-12Y: 10-15mg/Kg X2/D. >12y:250mg BD. Double in sever inf. AUGMENTIN ® ?X2 in severe infections < 1Y 1-6y >6y 7- 12y 156 mg/5ml 2.5 ml tds 156 mg/5ml 5 ml tds 312 mg/5ml 2.5 ml tds 400mg/5ml DUO 2mo-2y 0.15mg/kg bd 2-6y 2.5ml bd 7-12y 5ml bd >12 y 375 mg tab tds 625 mg tab tds for severe infections ACETAMINOPHEN= PARACETAMOL X3-4/d Drops 100mg/ml syrup 120 mg/5ml supp ….100,200,350 mg 90mg/kg/d %3-4 Syrup Supp <1y drops 1/2-1ml 2.5-5ml 100mg 1-6y 5-10ml 200mg 6-12y 10-20ml 350mg ZOVIRAX (Acyclovir)susp.200mg:5ml dose:80mg/kg/d%4 X 5-7 Days HZV,HSV,CHICKENPOX

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ZITHROMAX 200mg/5ml Oral suspension 10 mg/kg/d once dailySUPRAX ,SEFRAX SEFIXIME 1OO mg/5ml Oral suspension 8mg/kg/d % 1-2Zinnat (cefuroxime): suspension 125mg/5ml,Tablet &sachets.

Dose: 3mo-12Y: 10-15mg/Kg X2/D. >12y:250mg BD. Double in sever inf.AUGMENTIN ?X2 in severe infections

< 1Y

1-6y

>6y

7-12y156 mg/5ml 2.5 ml tds

156 mg/5ml 5 ml tds

312 mg/5ml 2.5 ml tds

400mg/5ml DUO2mo-2y 0.15mg/kg bd

2-6y 2.5ml bd

7-12y 5ml bd

>12 y 375 mg tab tds

625 mg tab tds for severe infections

ACETAMINOPHEN= PARACETAMOL X3-4/d

Drops 100mg/ml syrup 120 mg/5ml supp .100,200,350 mg

90mg/kg/d %3-4

SyrupSupp

7kg:20-30 mg/kg/d% 3-4Ponstan (Mefenamicacid)susp.50mg/5ml.D 25mg/kg/d%3 (cap250mg)

Campylobacter enteritis Ciprofloxacin Ciproxin 250 mg:5ml 7.5 mg/kg/bdErythromycin

SalmonellosisTrimethoprim

Typhoid feverCefotaxime or Chloramphenicol

ShigellosisTrimethoprim or Amoxicillin

Infant colic: Rr Simeticone: -INFACOL Liquid. 40mg:1ml .dose: 0.5-1ml x max 6doses.with feed.

- Dentinox colic drop 21mg:2.5ml. dose: 2.5ml x max 6 doses.with feed.METRONIDAZOLEAnaerobic pathogens anti-infective agent.Giardiasis, Amoibiases & Antibiotic associated colitis = Pseudo membranous colitis Ulcerative gingivitis

NB: 15mg/kg/day %3

>:15-30mg/kg/day %3For 5-7 day, Give 10 days for abscess.

( diloxanide furoate 6.6 mg/kg tds, < 12y:500mg tds for 10 days 1-3Y: 50mg tds

3-7Y: 100 mg bd

7-10Y: 100mg tds

< 10Y: 200mg tds

Ad.Trichomoniasis: 2 g Single dose, 500%2X10days

Ad.Non specific vaginitis:500mg bd X7days

Flagyl 125-200mg/5ml,Tab 200,400,500mg.IV infu 5mg/ml,Supp500mg.X:? pregnancy & lactation

Local Mouth analgesic: Benzydamine(Difflam spray and mouth wash)3-4 puffs 2-3 hourly.

Thrush treatment: Nystatin oral suspension (100.000U/ml,not absorbed) NB.1-2 ml qds +/- Miconazole (Absorbable antifungal with some antibacterial activity mainly against Str.&G+) Daktarin oral gel 2ml?> bd.Anti-emetics

Antihistamines: Sedating: Promethazine HCl (Phenergan)FENISTIL(DIMETHINDENE) DROPS 1mg/ml. Sy 0.5mg/5ml.

Dose:< 1y: 3-10 D tds 1-3y: 1 tsf tdsPhenergan Elixir 5mg/5ml, Tab.10mg, Inj 25mg/ml

Indications Age/ mg2-5 Y5-10 Y>

Symptomatic relief of allergy, hayfever, Insomnia associated with urticaria &Pruritus5-1510-2510-20

/mg d 1-2

Nausea &vomiting12.5-37.525-75

Motion sickness prevention51020-25 bed time

Severe vomiting in pregnancy25mg increase SOS to 100mg at bed time

:Non sedating:Cyclizine(Valoid), Cinnarizine(Stugeron)

Domperidone (Motilium: Susp 5mg/5ml, Supp 30 mg.)

Dose:Oral :35kg10-20 mg 3-4 time/day

Rectal: 35kg 60mg bdMetoclopramide (PRIMPERAN 20mg Supp. ) > 40Kg ?qds (Maxolon :Paediatric liquid &Syrup 1mg/ml, Tab 10mg,Inj 5mg/ml)

Dose any root: NB-1Y: 100 microgram/kg bd NB 3-4 times/day.

1-3Y: 1mg 2-3/day

3-5Y: 2mg 2-3/day

5-9Y: 2.5mg tds

9-18Y : 5 mg tdsDopamine antagonist: Phenothiazines: Chlorpromazine (Largactil :Syrup 25mg/5ml, Suspension fort 100mg/5ml,Tab.10mg,Inj.25mg/ml.!! Contact sensitivity.)

Indications

Persisting nausea & vomiting.

Childhood schizophrenia and other psychoses

Relief of acute symptoms of psychoses

Induction of hypothermia to prevent shivering.

Neonatal abstinence syndrome?????( by mouth 2-3 mg/kg/day 3-4 dose)Dose:1-12Y:500microgram/kg Oraly 4-6 hour.IM 6-8 hour.

Pro chlorperazine(Stemetil :Syrup5mg/5ml, Eff.granules 5mg, Supp.5mg,Inj.12.5mg/ml)

AGEORAL

mg.tdsRECTAL

mg.tdsIM mg.tds

1-5y1.25-2.52.51.25-2.5

5-12y2.5-55-105-6.25

12-18Y5-1012.5-2512.5

Perphenazine

Trifluoperazine

Antipsychotic: Haloperidol Levomepromazine (methotrimeprazine)

CONSTIPATION

1 - Initial EvacuationOsmotic laxatives sos Bowl cleansing solutionsLactulose;Duphalac, Lactogal,Regulose Susp. 3g/5ml1mo.-1y 2.5ml, 1-5y 5ml, > 5y 10-15 ml bd Na-Bicosulphate= SKYLOX Drops 5-10 drops ,Picolax Oral sachet. 1-2y 1/4 sach., 2-4y 1/2 sach., < 4y 1 sach. bd. Solve at 150ml water(acts within3h) usually achieves evacuation, which may be repeated if necessary. {if no response: give paraffin oil sos picolax } {*>2y.Faecal impaction} Osmotic laxatives NG administration of Macrogols(polyethylene glycol): Movicol oral pawder sachet-solution until clear faecal effluent is achieved or for rectal evacuation under anaesthetic.2- Maintenance treatment (>3mo.)

Osmotic laxatives Lactulose: Duphalac,Lactogal,Regulose Susp.3g/5ml Oral.1mo.-1y 2.5ml, 1-5y 5ml, < 5y 10-15 ml bd + (5 days SOS Stimulant laxative:DocustateNa:Dioctyl ,Docusol ,Norgalax micro-enema. Stimulant &Softening agent. Ped sol < 6mo, 12.5mg tds. Enema < 12Y {Or Senna: Senacot Susp. 1mo-2y 2.5ml, 2-6y 5ml < 6y 5-10ml Once daily}Anal fissures

Topical scheriproct - hydrocortisone cream is better than lignocaine jelly.

Chronic anal fissures needs topical Glyceryl trinitrate (0.2-1%) ointment to relax the anal sphincter, relives pain and aid healing of anal fissure. Diltiazem 2% ointment could be used for resistant cases. Surgery for the more resistant.

Abortion

Mifegyne tab + Cytotec tab (or Gemoprost 1mg pessaries (box 5 pss))

1 Mifegyne 200 mg tab O + Cytotec 200 microgram ( 4 tab=800 microgram) tab Vaginaly:

< 9 W= < 2 mo: 1-3 day if no bleeding after 4 h repate 400 microgram

9-13 W=2-3 mo: 36-48 h 400 microgram 3 Hourly X 4 Vaginaly or Oraly

13-24W=3-6 mo: 36-48 h 400 microgram 3 Hourly X 4 Oraly

O R : Gemoprost 1mg pessaries (box 5 pss) 3 hourly vaginaly X5Contraceptive ta:Microgynon,Losynon--------------------------------------------------------------------------------------------------------------OFRAMAX=ROSEPHEN = cefitriaxon 50-80mg/Kg/D (SUPRAX = CEFIXIME)

Ciproxin susp.for enteritis 250/5m.7.5mg/kg/bd Antibacterial forUTI&GE * G-VE,CHLAMIDIA& SOM MYCOBACTERIA, PSEUDOMONAL INFECTION,ANTHRAX,SALMONELLA,SHIGELLA,CAMPYLOBACTER,NEISSERIA = GONORRHOEA, PSEUDOMONASGERAMYCINELOZENGUS: ANGINOVA, TRACHITOL, ROFAR, STREPSILS

-----------------------------------------------------------------------------------------Phenergen, ZYRTEC,SOOLAN,DULSANA,AMIDRAMINE,POLORAMINE. ZADITEN

SINGULAIR GRANUL > 6M ONCE DAYLY (Moderate BA+Rhinitis) = steroidFLIXONASE , FLOMIST Aqueous nasal spray Nasal corticosteroid nasal drops +/- Antihistamines

RINATEC Nasal spray 2puffs BD for watery vasomotor rhinitis

VIBROSIL

FEROGLOBINE

VASOGEN CREAM ( when infected ), SUDOCREAM EMLA CREAMOTOCAL EAR DROPS

PERMETHRINE 5% CREAM=LYCLEAR DERMAL CREAM for scabies and lice apply once weekly for 2 weeksPARA SHAMPOO WEEKLY X 3 FOR HAIR LICEEURAX cream and solutionZENTEL

--------------------------------------------------------------------

Milk Infant formular:SIMILAC advance. Similac gain >6m on mixd diet.

Feed thickened: Enfamil AR. NESTSRGEL. SMA Staydown.

Special diet: Energivit (protein free CHO). Generaid (whey protein). MCT Peptide (AA+MCT+CHO). Nepro ( high energy low electrolyte).

Intolerance: Enfamil lactofree. Isomil. Pregestimil ( gluten,sucrose &lactose free). Wysoy (Whole caws milk, Lactose& Galactos sensitivity).

Night terrors and sleep-walking : hypnotics : Melatonin?MANAGEMENT OF ACUTE ASTHMA1. Short acting B2 agonists MDI via Spacer devices & close fitting face mask. Give 1 puff every 15-30 sec.X10, Repeat dose after30 min if necessary. Reducing frequency to every 1-4 hours when condition improves. POOR RESPONSE 2. Oxygen to achieve oxygen saturation above 92%.

+ 2.5-5 (mg or ml) Neb.Salbutamole or 5 mg = ml Terbutaline(Bricanyl) repeat dose every h if necessary then reduce frequency according to response .POOR RESPONSE3. Add.Neb.Ipratropium Bromide(Atrovent) 125-250 microgram(-1ml) every h for the first 2 hours. Reduce dose frequency as condition improves.

+ Oral prednisolone 1-2 mg/kg max 40 mg.once daily for 3-5 days.(if oral administration is not possible give IV hydrocortisone 4mg/kg repeated 6 hourly)POOR RESPONSE4. IV.short acting 2 agonist or aminophyllineMANAGEMENT OF CHRONIC ASTHMA

Types of

Ch.

BA

Infrequent Episodic

3/4 of asthmatics.

< 4 Episode / YFrequent Episodic

1/5 of asthmatics Have symptoms every 2-4 wksPersistent asthma

< 5%

Not Step1Step 2Step 3Step 4

?

modified- release oral 2 antagonist

Theophylline Nuelin SAAminophylline Phyllocontin continus any age.bd?

modified- release oral thiophylline

Singulair or Accolate> 6mo.once /d Leukotriene receptor antagonistLeukotriene receptor antagonist

MDI Salmetrol serevent or Formetrol foradil >2y bd Long acting 2 antagonistLong acting 2 antagonist

Inhaled steroidInhaled steroid

High Dose

SOS2Bronchodilatore2Bronchodilatore

Anti epilepticsVALPROATE (EPILIM 200mg/5ml. ) *>2Y.

Dose: Neonate:20mg/kg/day once daily. 1mo=12Y:10-15 mg/kg/day %2, >12Y 300mg bd& CARBAMAZEPINE (TEGRETOL Liquid :100mg/5ml, Supp:125mg) Dose oraly:1mo -12 Y: 5mg/kg/day at night or %2 increase SOS the maintenance dose 5mg/kg bd or tds. >12 Y:100-200 mg 1-2 daily increase to usual maintenance 400-600 mg bd or tds.

By rectum: Use approximately 25% more than the oral dose up to 4 times daily.FEBRILE CONVULSION:prolonged = > 15 ",or recurrent Rectally DIAZEPAM 500microgram/Kg max 10 mg repeated SOS.DYSTONIA Cerebral palsy :Broflex syrup 5mg/5ml.

Dose:1-2 mg daily % 1-2 doses. adjust according to response.

TREMOR,CHOREA&TICS: PROPRANOLOL Syprol 5mg/5ml Dose 6-15 mg/kg /day% 3. HALOPERIDOL Serenace 2mg/ml :( antipsychotic drug {thought disorder,hallucinations, delusions& hyperactive psychotic states. intractable hiccup}) Improving motor tics ,symptoms of Gilles de la Tourette syndrome and related coreas.Dose:>2Y 50 microgram/kg/day%2, Increase and adjust according to responseFungal infections

Tinea capitis (scalp ringworm), the most common fungal infection, produces irregular balding areas, scaling, and erythematous lesions. As these lesions enlarge, their centers heal, causing the classic ring-shaped appearance. Surrounding the balding areas are broken scalp hairs. When they break off at the scalp surface, hairs resemble black dots. Other findings include pruritus and thick, whitish nails.Allopecia TratmentMINOXIDIL = ROGAINE SOLUTION 2% OR 5 % BD

+

ANTHRALIN CREAM DAYLYDiagnosis of Celiac Disease

Serologic Tests

1. EMA (Immunoglobulin A anti-endomysium antibodies)

2. AGA (IgA anti-gliadin antibodies) Some people do not produce IgA antibodies.

3. DGP (Deamidated gliadin peptide antibody)

4. tTGA (IgA anti-tissue transglutaminase)