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Epidemic Modeling with Cellular Automata Bernadetta Stachura-Terlecka, Antoni Lig˛ eza 07.03.2018 BST ALI ( ) Epidemic Modeling with Cellular Automata 2018 1 / 12

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Page 1: Epidemic Modeling with Cellular Automata · 2018-03-16 · Epidemic Modeling with Cellular Automata Bernadetta Stachura-Terlecka, Antoni Ligeza˛ 07.03.2018 BST ALI ( )Epidemic Modeling

Epidemic Modeling with Cellular Automata

Bernadetta Stachura-Terlecka, Antoni Ligeza

07.03.2018

BST ALI ( ) Epidemic Modeling with Cellular Automata 2018 1 / 12

Page 2: Epidemic Modeling with Cellular Automata · 2018-03-16 · Epidemic Modeling with Cellular Automata Bernadetta Stachura-Terlecka, Antoni Ligeza˛ 07.03.2018 BST ALI ( )Epidemic Modeling

Outline1 State of the art

2 Classical CA in use

3 History

4 Epidemic as conflict

5 Representation for MultiLayered Cell

6 Movement phase

7 LCCA rule

8 Modeling results

9 Problems and future work

10 Bibliography

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Page 3: Epidemic Modeling with Cellular Automata · 2018-03-16 · Epidemic Modeling with Cellular Automata Bernadetta Stachura-Terlecka, Antoni Ligeza˛ 07.03.2018 BST ALI ( )Epidemic Modeling

State of the art

z Modeling of epidemy is both of theoretical interest and practicalimportance,

z There exists several mathematical models of epidemyz Cellular Automata can serve as a basig modeling tool for such

spatial phenomena,z There exists several models of epidemy with CA in the literatur,

but only classical CA are in use.

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Page 4: Epidemic Modeling with Cellular Automata · 2018-03-16 · Epidemic Modeling with Cellular Automata Bernadetta Stachura-Terlecka, Antoni Ligeza˛ 07.03.2018 BST ALI ( )Epidemic Modeling

Modeling used classical CA

Figure: HIV modeling used classical CA

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Page 5: Epidemic Modeling with Cellular Automata · 2018-03-16 · Epidemic Modeling with Cellular Automata Bernadetta Stachura-Terlecka, Antoni Ligeza˛ 07.03.2018 BST ALI ( )Epidemic Modeling

Epidemic modeling

z Daniel Bernoulli - first matematical epidemic model - Structure ofBernoulli’s model - the population is divided into susceptibles, i.e.those who have not yet been infected, and immunes, i.e. thosewho have been immunized for the rest of their life after oneinfection.

z SIS, SIR, SEIR, SIRSz Threshold analysis - The model is based solely on the user’s

response to the drug, and it is shown that when a certaincombination of susceptible population size, individualsusceptibility, and infectiousness does not exceed a criticalthreshold value, there will be only few users.

z Reed–Frost model - is one of the simplest stochastic epidemicmodels. It was formulated by Lowell Reed and Wade Frost in 1928and describes the evolution of an infection in generations.

BST ALI ( ) Epidemic Modeling with Cellular Automata 2018 5 / 12

Page 6: Epidemic Modeling with Cellular Automata · 2018-03-16 · Epidemic Modeling with Cellular Automata Bernadetta Stachura-Terlecka, Antoni Ligeza˛ 07.03.2018 BST ALI ( )Epidemic Modeling

Epidemic as conflict

parties to the conflictz virus expansion,z treatment, vaccine.

Epidemic is a spatial conflict with two actors (virus and human).

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Page 7: Epidemic Modeling with Cellular Automata · 2018-03-16 · Epidemic Modeling with Cellular Automata Bernadetta Stachura-Terlecka, Antoni Ligeza˛ 07.03.2018 BST ALI ( )Epidemic Modeling

LCCA

Figure: Graphical presentation for MultiLayered Cell use in LCCA

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Page 8: Epidemic Modeling with Cellular Automata · 2018-03-16 · Epidemic Modeling with Cellular Automata Bernadetta Stachura-Terlecka, Antoni Ligeza˛ 07.03.2018 BST ALI ( )Epidemic Modeling

Movement phase

z Select a random cell (infected peoples) from the countries,z For each of the individuals in the cell, randomly select a

neighbouring cell and move the individual into it (cell not beingfull),

z Repeat from step one until all the cells in the area have beenaccounted for,

z In every cells where was infected peoples set virus and time for24h in Layer 1,

z Every infected man heve set time = 216h in Layer 2,z Compute contact infections,z Repeat from step four for the next cell until all cells have been

accounted for.

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Page 9: Epidemic Modeling with Cellular Automata · 2018-03-16 · Epidemic Modeling with Cellular Automata Bernadetta Stachura-Terlecka, Antoni Ligeza˛ 07.03.2018 BST ALI ( )Epidemic Modeling

Rule

Virus Layer:z live time (max 24h)z A type flu - Z(C1n) = xy ∗ ZarA ∗ W

z B type flu - Z(C1n) = xy ∗ ZarB ∗ W

Medicine Layer:z Spread of virus (max 216h)z A type flu - vactine person - C2n = 0, 6 ∗ Z(C1n)

z B type flu - vactine person - C2n = 0, 4 ∗ Z(C1n)

z resistant person - C2n = 0 ∗ Z(C1n)

z C2n = Z(C1n)

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Page 10: Epidemic Modeling with Cellular Automata · 2018-03-16 · Epidemic Modeling with Cellular Automata Bernadetta Stachura-Terlecka, Antoni Ligeza˛ 07.03.2018 BST ALI ( )Epidemic Modeling

Modeling results

Figure: Modeling results

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Page 11: Epidemic Modeling with Cellular Automata · 2018-03-16 · Epidemic Modeling with Cellular Automata Bernadetta Stachura-Terlecka, Antoni Ligeza˛ 07.03.2018 BST ALI ( )Epidemic Modeling

Problems and future work

Problems under investigation:z modeling the rules of propagation and interaction (x, y

parameters),z validation of the rules,z validation of the final results,z model tuning,

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Page 12: Epidemic Modeling with Cellular Automata · 2018-03-16 · Epidemic Modeling with Cellular Automata Bernadetta Stachura-Terlecka, Antoni Ligeza˛ 07.03.2018 BST ALI ( )Epidemic Modeling

Bibliographyz 1. J. D. Murray: Wprowadzenie do biomatematyki [Introduction to

Biomathematics], Wydawnictwo Naukowe PWN, 2006z Polish National Institute for Hygiene – NIPH:

http://wwwold.pzh.gov.pl/oldpage/epimeld/grypa/index.htmz B. Stachura-Terlecka, A. Ligeza: Modeling and analysis of spatial

conflicts with Layered Competitive Cellular Automata in:Multimedia Communications, Services and Security , 2015,

z S. Ching Fu, G. Milne: Epidemic Modelling Using CellularAutomata

z S. Yan, D. He, J. Luo, W.Chen, X. Yang, M. Wei, X. Kong, Y. Li, X.Feng and Z. Zeng: Simulation of HIV/AIDS distribution using GISbased cellular automata model

z F.C.Hoppensteadt, J.D.Murray: Threshold analysis of a drug useepidemic model

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