enzyume reaction in body a quick guide
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DOPA Dopamine
?
1) Mention the name of the enzyme?
2) Name one drug that inhibit this
enzyme?
Answer: nzyme:DOPA de!arbo"y#ase
Drugs: $arbidopa%
benserazide
&2'($O2 &2$O ? *!arboni!a!id)
1) Mention the name of the enzyme?
2) Name one drug that inhibit this
enzyme?
Answer: nzyme : $arboni! anhydrase
Drugs: A!etazo#amide%
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Dorzo#amide%Methiazo#amide
Angiotensin I Angiotensin II
?
1) Mention the name of the enzyme?
2) Name one drug that inhibit this
enzyme?Answer: nzyme :
Angiotensin !on+erting enzyme
Drugs: ena#apri# , #isinopri#,
!aptopri#, benazepri#, -uinapri#,
perindopri#, ramipri#, fosinopri#.
Acetylcholine Choline +Aceticacid
?
1) Mention the name of the enzyme?
2) Name one drug that inhibit this
enzyme?
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Answer: nzyme : !ho#inesterase
Drugs: physostigmine,neostigmine, pyridostigmine,D/P,
!hothiophate, Any Organophosphorus
$ompound ,drophonium,
0i+astigmine
cAMP 5- AMP (inactive)
?
1) Mention the name of the enzyme?
2) Name one drug that inhibit thisenzyme?
Answer: nzyme : phosphodiesterase
Drugs: inamrinone,
mi#rinone, si#denafi#
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Angiotensinogen Angiotensin - I
?1) Name the substan!e that is
in+o#+ed in this pro!ess?
2) Name one inhibitor?
Answer: nzyme : reninDrug: a#isiren,remiiren,
ena#iran
GTP cGMP
?
1) Mention the name of the enzyme?
2) Name one drug that a!ti+ates this
enzyme?
Answer: nzyme : guany#y# !y!#ase
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Drugs: g#y!ery# trinitrate,
isosorbide dinitrate
ATP CAMP
?1) Mention the name of the enzyme?
2) Name one drug that a!ti+ates this
enzyme?Answer: nzyme : adeny#y# !y!#ase
Drugs:ephedrine,
adrena#ine,sa#butamo#, ritodrine,
terbuta#ine
Acetylcholine Choline +Aceticacid
?
1) Mention the name of the enzyme?
2) Name one drug that a!ti+ates this
enzyme?Answer: nzyme : $ho#inesterase
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Drugs: Pra#ido"ime,
Obido"ime, Dia!ty# mono"ime
Norepinephrine Inactive
eta!olite
?1) Mention the name of the enzyme?
2) Name one drug that inhibit thisenzyme?
Answer: nzyme : monoamine
o"idase% !ate!ho# ortho methy#
transferase
Drugs: MAO inhibitor:4e#egi#ine
$OM5 inhibitor: 5o#!apone,
nta!apone
Angiotensin II AT" receptors
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1) Mention two drugs a!ting at the
A51 re!eptors
Answer:Drugs: #osartan, !andesartan,+a#sartan,irbesartan,eprosartan.
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1)What is meant by indirect acting?2)Name one drug which acts indirectly?
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Answer: 1) A!t by re#easing
norepinephrine from sympatheti! ner+eendings
2) Amphetamine,5yramine,phedrine
Answer: 1) drugs a!ting both dire!t9
indire!t means
1)What is meant bymixed acting?
2)Mention one drugwhich acts so
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2) ephedrine, metho"amine
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1)What is meant by direct acting?
2)Name one drug which acts indirectly?
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Answer: 1) ;y intera!ting withadrenergi! re!eptors
2) Noradrena#ine,Adrena#ine, Dopamine,
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Answer: 1) any >agonist adrena#ine,
isoprena#ine, sa#butamo#, terbuta#ine,
sa#metro#
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1) Name the two agonists
acting on this site?
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1)Name two antagonists
acting at this site?
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Answer: 1) any >b#o!er : praprano#o#,
nado#o#, timo#o#, sota#o#, metopro#o#,
ateno#o#, a!ebuta#o#, #abeta#o#, !ar+edi#o#
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Answer: 1) Phosphodiesterase inhibitor:
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Answer: 1) !a#!ium !hanne# b#o!ers :
nifedipine, am#odipine, fe#odipine,
nimodipine, ni!ardipine, isradipine.
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1)Name two drugs acting at this
site?
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PA#A $I%&$'*IC
? ACI$
1) Name the enzyme?
2) Name one inhibitor of that
enzyme?
Answer: nzyme : /o#i! a!idsynthetase Drugs: 4u#phonamides,
4u#fone
$% TT'A%&$'
? *IC ACI$
1) Name the enzyme ?2) Mention one inhibitor of the
enzyme?
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Answer: nzyme : dihydrofo#ate
redu!tase
Drugs: 5rimethoprim,Pyrimethamine, Methotre"ate
,ANT%IN 'IC ACI$
1) Name the enzyme ?
2) Mention one inhibitor of the
enzyme?Answer: nzyme : @anthine o"idase
Drugs: A##opurino#
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