enzymes
TRANSCRIPT
ENZYMES
http://www.biologie.uni-hamburg.de/b-online/library/cat-removed/enzyme_.gif
Enzymes are proteinsChemical reactions need help to
get started.
Ex: A fire needs a match to get it started.
The reactants (what you start with) need help to carry out the chemical reaction to develop the products
http://www.chuckwagondiner.com/art/matches.jpghttp://plato.acadiau.ca/COURSES/comm/g5/Fire_Animation.gif
______________ to get a chemical reaction _______________
= ________________________
Image from: Pearson Education Inc, publishing as Pearson Prentice Hall. All rights reserved
ACTIVATION ENERGY
REACTANTSPRODUCTS
ACTIVATIONENERGY
Energy requiredSTARTED
Exergonic Reactions
Fre
e e
nerg
y
Progress of the reaction
∆G < O
EA
Figure 8.14
A B
C D
Reactants
A
C D
B
Transition state
A B
C D
Products
___________ HELP CHEMICAL REACTIONS _______________
by ____________ the___________________________to get a chemical reaction started.
Image from: Pearson Education Inc, publishing as Pearson Prentice Hall. All rights reserved
DECREASING
Enzymes
ACTIVATION ENERGY required
HAPPEN FASTER
Progress of the reaction
Products
Course of reaction without enzyme
Reactants
Course of reaction with enzyme
EA
withoutenzyme
EA with enzymeis lower
∆G is unaffected by enzyme
Fre
e e
nerg
y
Figure 8.15
PROTEINS CAN BE ENZYMES
SUBSTRATE
ENZYME-SUBSTRATE COMPLEX
PRODUCTSENZYMEUnchanged& Reusable
ENZYME
Image modified from: http://www.biologie.uni-hamburg.de/b-online/library/cat-removed/enzyme_.gifArrow: http://www.gifanimations.com/action/ImageDisplay/1/2/11/next
ACTIVESITE
ENZYMES _____ like a _______________
to only _________of _________.
Enzymes are ___________ by thereaction and ___________
LOCK AND KEY
REUSABLEUNCHANGED
FIT
ONE KIND SUBSTRATE
http://www.grand-illusions.com/images/articles/toyshop/trick_lock/mainimage.jpg
FACTORS THAT AFFECT ENZYME ACTIVITY
__________ & ______________
Conditions that are TOO ACIDIC
or TOO HOT cause proteins to________ or _________
pH temperature
UNWIND DENATURE
http://www.desktopfotos.de/Downloads/melt_cd.jpg http://www.nealbrownstudio.com/adm/photo/163_nb_fried_egg.jpg
See a movieChoose narrated
Progress of the reaction
Products
Course of reaction without enzyme
Reactants
Course of reaction with enzyme
EA
withoutenzyme
EA with enzymeis lower
∆G is unaffected by enzyme
Fre
e e
nerg
y
Figure 8.15