embryology brain

8/19/2019 Embryology Brain

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EMBRYOLOGY-

BRAINR.M


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FORMATION OF NEURAL TUBE


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DEVELOPMENT OF BRAIN


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DEVELOPMENT OF BRAIN

At 5th week AOG


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TELENCEPHALONCerebral hem!"here!#ar!e at the be$%%%$ &' 5th week &'

(e)*t a! blateral e)a$%at&% &' the lateral wall &' the"r&!e%+e"hal&%

,%( m&%th- ba!al "art &' hem!"here be$%! t& %+rea!e %!e#####"+t/re

0th '/rther e1"a%!&% &' the hem!"here!- t +&)er! the

lateral a!"e+t &' (e%+e"hal&%- me!e%+e"hal&% a%(+e"hal+ "&rt&% &' mete%+e"hal&%.

0th +&%t%&/! $r&wth &'+erebral hem!"here! %a%ter&r-(&r!al a%( %'er&r (re+t&%!####'&rmat&% &'frontal, temporal and occipital lobes

The area betwee% 'r&%tal a%( tem"&ral be+&me (e"re!!e(a%( ! +alle( the insula.

2/r'a+e &' +erebral hem!"here! $r&w! ra"(l3 that ma%3+&%)&l/t&%!4$3r !e"arate( b3 6!!/re! a%( !/l+ a""ear.


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CEREBRAL CORTE7De)el&"! 'r&m the

"all/m Tw& re$&%!8

a"ale&"all/m9ar+h"all/m# area mme(atel3

lateral t& the +&r"/!!trat/m

b%e&"all/m#betwee%the h""&+am"/! a%(

"alle&"al/m


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C&r"/! 2trat/mBe%$ "art &' wall &'

the hem!"here-e1"a%(! "&!ter&rl3a%( ! ()(e( %t&8

aCa/(ate %/+le/!#(&r!&me(al "&rt&%

bLe%t'&rm#)e%tr&lateral "&rt&%

I%ter%al +a"!/le#()(e!

the a9b re"re!e%t! b3the a1&%! "a!!%$thr&/$h a%( 'r&m the+&rte1 &' hem!"here

At !ame tme# me(al

wall &' thehem!"here a%(lateral wall &'(e%+e"hal&% '/!e

a%( the +a/(ate%/+le/! a%( thalam/!+&me %t& +l&!e+&%ta+t.


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H""&+am"/! Th+ke%%$

mme(atel3 ab&)ethe +h&r&( 6!!/re

Gra(/all3 b/l$e! %t&the lateral )e%tr+le!

&l'a+t&r3 '/%+t&%


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DIENCEPHALON

De). Fr&m the me(a%"&rt&% &'

"r&!e%+e"hal&%

C&%!!t &' tw& alar "late!

a%( r&&' "late

aR&&' "late! #$)e r!e t&

+h&r&( "le1/! &' the thr()e%tr+le

bCa/(al "art &' R&&'"late#(e)el&"! %t& pinealbod or epip!sis- !&l(&r$a%- !er)%$ a! +ha%%elthr&/$h wh+h l$ht a%((ark%e!! a:e+t!

Alar "late!#thalam/!

4(&r!al a%(h3"&thalam/!4)e%tral- !e"arate( b3 theh3"&thalam+ !/l+/!

; D/e t& "r&l'erat)ea+t)t3 &' Thalam/!- t"r&


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DIENCEPHALON$pot!alamus-

D:ere%tate! %t& a%/mber &' %/+leararea! !er)%$ a!re$/lat&r3 +e%ter! &'

)!+eral '/%+t&%!-%+l/(%$8

a2lee"

bD$e!t&%

+B&(3 tem".

(Em&t&%al beha)&r

Mammlar3 b&(3#&%e&' the $r&/"!- '&rm%$a (!t%+t

"r&tr/bera%+e &%)e%tral !/r'a+e &'h3"&thalam/! &%ea+h m(l%e


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RHOMBENCEPHALONMYELEN%E&$ALON-

#$)e r!e t& me(/lla&bla%$ata

#It ha! alar a%( ba!al "late!

#ba!al "late! +&%ta%! m&t&r%/+le

#%/+le are ()(e( %t&8aMe(al !&mat+ e:ere%t$r&/"

bI%terme(ate !"e+ale:ere%t $r&/"

+Lateral $e%eral )!+erale:ere%t $r&/"

Me(al !&mat+

aH3"&$l&!!al %er)e#!/""l3 the t&%$/em/!+/lat/re

bAb(/+e%!

+Tr&+hlear(O+/l&m&t&r

.!"e+al )!+eral e:ere%t#!/""le! the !trate( M &'"har3%$eal ar+he!

aA++e!&r3 N

bVa$/! N

+Gl&!!&"har3%$eal N


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MEDULLA OBLANGATA

Ge%eral )!+eral

e:ere%t $r&/"#+&%ta%! m&t&r%e/r&%! that !/""l3the %)&l/%tar3

m/!+/lat/re &' there!"rat&r3-%te!t%ala%( the heart

Alar "late +&%ta%! =$r&/"! &' !e%!&r3%/+le

a2&mat+ a:ere%t#lateralre+e)e! m"/l!e! 'r&m theear a%( !/r'a+e &' hea( b3wa3 &' CN VIII a%( CN V

b2"e+al )!+eral a:ere%t$r&/"# %terme(ate

#re+e)e! m"/l!e! 'r&mta!te b/(! &' t&%$/e- 'r&m"alate-&r&"har3%1-e"$l&tt!

+ Ge%eral )!+erala:ere%t#

Im"/l!e! 'r&m GIT a%(Heart


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Mete%+e"hal&%%erebellum#

'/%+t&%! a!+&&r(%at&% +e%ter'&r "&!t/re a%(m&)eme%t

&ons#!er)e! a!"athwa3 '&r %er)e

6ber! betwee% the!"%al +&r( a%( the+erebral a%(+erebellar +&rt+e!


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Me!e%+e"hal&%#M(bra% The m&!t "rmt)e &'

the bra% )e!+le!Ba!al "late +&%ta% ,

$r&/" &' m&t&r %/+le

aMe(al !&mat+ e:ere%t

#re"re!e%te( b3 CN IIIa%( IV

b2mall $e%eral )!+erale:ere%t# re"re!e%t! b3%/+le/! &' E(%$er >

we!t"hal-wh+h%%er)ate! the !"h%+ter

"/"llar3 M

Mar$%al la3er &' ea+hba!al "late e%lar$e! a%(

'&rm +r/! +erebr- !er)e!a! "athwa3 '&r %er)e 6ber(e!+e%(%$ 'r&m +erebral+&rte1 t& "&%! a%( !"%al

+&r(Alar "late!#$)e r!e t&

a%ter&r4!/"er&ra%("&!ter&4%'er&r +&ll+/l/!

2/"# +&rrelat&% a%( re?e1

+e%ter '&r )!/al m"/l!e!I%'er&r#rela3 !tat&% '&r

a/(t&r3 re?e1e!


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Cr/! +erebr


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'(AGE' O) BRAIN *E+ELO&MEN( AN* A''O%IA(E* *I'OR*ER'

%toenesis *eelopment

of moleculesinto cells

%onenital

neoplasms

$istoenesis *eelopmentof cells intotissues

Neurocutaneous sndromeso (uberoussclerosiso

Neuro/bromatosis%onenitalascular

malformations


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Neural (ube

%losure

*orsalinduction

0-123s AOG

- %!iarimalformations

- Aenesis ofcorpus callosum- Lipoma ofcorpus callosum- *and-4al3er

malformation"ariant- &osterior fossaarac!noid cst

- (eratoma

*ierticulation+entralinduction5-623s AOG

-$oloprosencep!al


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Neuronal&roliferation

7-86 23s AOG

NeuronalMiration

91 23s AOG toears

Lissencep!al

'c!i:encep!al

$eterotopias&ac!microria"polmicroria

Melini:ation Birt! to ears *isorders


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Melini:ation

Birt! to ears *isorderst!at a;ect2!ite matter *isorders

t!at a;ectra matter *isorderst!at a;ect

ra < 2!itematter Basalanliadisorders

*isordersIndependentof (imin

*estructie

&orencep!aliccst

$dranencep!


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embryology brain

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