EFFECT OF SMOKING HABITS ON THE FRACTIONAL EXHALED NITRIC OXIDE (FeNO)

VALUES

PROTOCOL PRESENTATION

Class 22008/2009

• Adelaide Alves • Aida Moreira • Ana Alves• Bítia Vieira• Daniel Braga • Hugo Duarte• Joana Moura

Serviço de Bioestatística e Informática Médica18 de Dezembro de 2008

OBJECTIVES

• Evaluate FeNO values in healthy and asthmatic individuals

• Determine and quantify the effect of smoking habits on the values of FeNO

METHODS

Systematic review

Databases used: Pubmed ScopusISI web of knowledgeGoogle Scholar

ARTICLE INCLUSION AND EXCLUSION CRITERIA

• healthy or asthmatic adults• NIOX, ECOMEDICS or LOGAN• effects of smoking habits

•animals or children•non standardized online method (50 mL/s) •other health problems•full text not available

Author Year of publication n Equipment used to

measure the exhaled

NO

Assessed factors

Malinovschi 2006 221 adult subjects from

the European

Community Respiratory

Health Survey II

Not mentioned Exhaled NO

Lung function

Immunoglobulin E

sensitisation

Smoking habits

Mario Olivieri 2006 204 healthy, non-

smoking adults, with

normal spirometry

values

EcoMedics FeNO

RESEARCH QUESTION

How do smoking habits affect the exhaled nitric oxide values in healthy and

asthmatic people?

QUERY

Exhaled nitric oxide AND (smok* OR cigarette OR tobacco) AND asthma

Exhaled nitric oxide AND (smok* OR cigarette OR tobacco) AND health

KEYWORDS• Asthma• Healthy people• Exhaled Nitric Oxide• Smoking

MeSH TERMS• Asthma• Health• Smoking• Nitric Oxide

THANKS…

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…thanks again!