EFFECT OF SMOKING HABITS ON THE FRACTIONAL EXHALED NITRIC OXIDE (FeNO)
VALUES
PROTOCOL PRESENTATION
Class 22008/2009
• Adelaide Alves • Aida Moreira • Ana Alves• Bítia Vieira• Daniel Braga • Hugo Duarte• Joana Moura
Serviço de Bioestatística e Informática Médica18 de Dezembro de 2008
OBJECTIVES
• Evaluate FeNO values in healthy and asthmatic individuals
• Determine and quantify the effect of smoking habits on the values of FeNO
METHODS
Systematic review
Databases used: Pubmed ScopusISI web of knowledgeGoogle Scholar
ARTICLE INCLUSION AND EXCLUSION CRITERIA
• healthy or asthmatic adults• NIOX, ECOMEDICS or LOGAN• effects of smoking habits
•animals or children•non standardized online method (50 mL/s) •other health problems•full text not available
Author Year of publication n Equipment used to
measure the exhaled
NO
Assessed factors
Malinovschi 2006 221 adult subjects from
the European
Community Respiratory
Health Survey II
Not mentioned Exhaled NO
Lung function
Immunoglobulin E
sensitisation
Smoking habits
Mario Olivieri 2006 204 healthy, non-
smoking adults, with
normal spirometry
values
EcoMedics FeNO
RESEARCH QUESTION
How do smoking habits affect the exhaled nitric oxide values in healthy and
asthmatic people?
QUERY
Exhaled nitric oxide AND (smok* OR cigarette OR tobacco) AND asthma
Exhaled nitric oxide AND (smok* OR cigarette OR tobacco) AND health
KEYWORDS• Asthma• Healthy people• Exhaled Nitric Oxide• Smoking
MeSH TERMS• Asthma• Health• Smoking• Nitric Oxide
THANKS…
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