drug abuse prathyusha
TRANSCRIPT
DRUG ABUSE
Prathyusha
Pharm-D 2nd year
Drug abuseIt refers to use of a drug by self medication in a
mannerand amount that deviates from the approved medical and social patterns in a given culture at a given time.The term conveys social disapproval of the manner
and purpose of drug use.for regulatory agencies,drug
abuserefers to any use of an ilicit drug
Drug addiction It is a pattern of compulsive drug use
characterized by overwhelming involvement.
With the use of a drug.procuring the drug and using it takes precedence over other activities.
Even after withdrawal most addicts tends to relapse.
Ex:Amphetamines,cocaine…
Drug habituation It denotes less intensive
involvement with the drug , so that its withdrawal produces only mild discomfort.
Consumption of tea,coffee,tobacco.
Commonly abused drugs
Depressants Stimulants Hallucinogens Marijuana Inhalants steroids
Depressants it shows brain and body reactiosbarbiturates,opiates,alcohol,heroinit shows contraction of pupils,clumsiness,sleepiness
Stimulants Stimulants cause brain and body
reactions to speed up. Cocaine ,nicotine,amphetamines,morp
hine. Dilated pupils,hyperactivity,euphoria Weightloss,dry mouth
Hallucinogens
Many natural products having
hallucinogenic property. These drugs which alters the
mood,behaviour thought and perception in a manner similar to that seen in psychosis.
LSD(lysergic acid diethylamide) It is synthesized by hofmann it is an
ergot alkaloids(mental effects and central
Sympathetic stimulation).
marijuana It act as an
depressant,stimulant,hallusinogen. It cause glassy,red eyes,loud talking,
loss of interest.
Inhalants Inhalants are extremely dangerous
can die from first time use mostly hydroflurocarbons,
Alkylnitrites,toluene,xylene
Watery eyes,anxiety,irritability,drowsiness,
headache,nausea.
SteroidsThese drugs to make users bigger, fasters,stronger can be take in the form of pill.
Way of consuming drugs
smoking snorting
Mechanism of action of cocaine Cocaine stimulates vagal center
vomiting centre, raise up in BP & pyrexia.
Cocaine blocks uptake of dopamine, noradrenalin and adrenaline into adrenergic nerve endings, resulting higher cocentration of the transmitter around the receptors. It shows sympathomimetic effect.
Leads to local vasoconstriction and tachycardia.
Mechanism of action of cocaine
Morphine
It is widely used for acute and chronic pain.
Route of administration oral&injections etc..
It causes sedation,depression,constipation,itching.
All opioid receptors are linked through G-proteins to inhibition of adenylate cyclase.
Mechanism of action of morphine
They are addicted
changes before -after
Counselling the ptients carefully
Anti drugs – listenning music , changing their habits, laughing,dancing.
Thank you