Hepatitis Serology Interpretation
Test Value Interpretation Actionanti-HAV Neqative Susceptible to HAV Vaccinate for HAV
anti-HAV Positivelmmune to HAV None RequiredlqM anti-HAV Neqative
anti-HAV PositiveAcute HAV infection Report & CounsellqM anti-HAV Positive
Test Value Interpretation ActionHbsAg Neqative
Susceptible to HBV Vaccinate for HBVanti-HBc Neqativeanti-HBs Negative
HbsAq Negativelmmune to HBV due to vaccination None Requiredanti-HBc Negative
anti-HBs Positive
HbsAs Negativelmmune to HBV due to infection Counsel & Treat as
Clinical ly Indicatedanti-HBc Positiveanti-HBs Positive
HbsAq Positive
Acute HBV infection Report & Counselanti-HBc PositivelqM anti-HBc Positiveanti-HBs Neoative
HbsAq Positive
Chronic HBV infection Repod & Counselanti-HBc PositivelqM anti-HBc Neqativeanti'HBs Neqative
4 Possible InterpretationsHbsAq Neoative 1. Recoverinu from acute HBV
Repoft & Counselanti-HBc Positive 2. Distantlv immune, .1. anti-HBV in serumanti-HBs Neqative 3, False pos anti-HBc-+Susceptible to HBV
4, Chronic, with J level of HbsAg in serum
-,T.€*-* Value: Interpretation Action
anti-HCV Positive Hiqh S/Co Acute, chronic. or past HCV infectionReport & Counsel
F/U Testinq: Genotype
anti-HCV Positive Low S/Co Possible lnfection Requires Confirmation Test
anti-HCV Negative No Current Infection Monitor & repeat test in 3-6months if cl inically indicated.
RIBA Positive Past or Current Infection F/U Testing: PCR or TMA
RIBA Negative False Positive anti-HCV Monitor & repeat test in 3-6months if cl inical ly indicated,
PCR or TMA Positive Current lnfection F/U Testing: Genotype
PCR or TMA Negative Past lnfection or False Positive anti-HCVF/U Testing: RIBA
Genotype 6 Possible Strains Type 1 Most Common in U.S. Guides Treatment Decision
Viral Load Copies/mL Quantifies Current HCV Infection Monitor Treatment
Liver Biopsy Histological Marker Grade the amount of necrosis andinflammation and to stage the degree offibrosis
Monitor Liver lnvolvement