Pathology of the
gastrointestinal tract II
(liver, pancreas).
X. practical training
3rd year Dentistry
Congestion of the liver
Congestion of the liver
Congestion of the liver (hepar moschatum)
1 Portobilial spaces
2 Ways of congestion (congestion with
necrosis of hepatocytes)
Pseudolobulus from residues of 3 lobuli, in
centre is portobilium
1
1
1
2
2
Congestion of the liver (hepar moschatum), detail
1
3
2
3
1 Portobilium- dilatated branch of v. portae
2 Pseudolobulus from residues of 3 lobuli, in centre is
portobilium
3 Ways of congestion (congestion with necrosis of
hepatocytes)
4 Biliary duct
5 Branch of a. hepatica
4
5
Liver steatosis
Viral hepatitis
HAV RNA hepatovirus
HBV DNA hepadnavirus
HDV RNA defektní virus
non A non B (NANB)
HCV RNA flavi a pestivirus-like
HEV RNA kalicivirus
HFV RNA togavirus
HGV RNA flavivirus
others: herpesvirus, cytomegalovirus, paramyxovirus, ...
Acute stage of
viral hepatitis
Viral hepatitis
subacute fatal
Chronic viral
hepatis
Liver – chronic viral hepatis
1
2
3 1 Portobiliar space with chronic inflammatory infiltrate
2 „piece-meal necroses“
3 Central part of lobulus with mixed steatosis
Liver – chronic viral hepatis
1
2
1 Chronic inflammatory
infiltrate in portobiliar space
2 Biliary duct
Cirrhosis of the liver
etiology morphology
alcohol 60-70% mikronodular
CAH 10% makronodular
kryptogenic 10-15% mixed
biliáry primary
secondary
pigment haemochromatosis primary
secondary
Congenital metabolic disorders (tyrosinemia,galaktosemia ...)
Cirrhosis of the liver
Cirrhosis of the liver
Cavernous haemangioma – liver
kopie
Primary liver
carcinoma
Hepatocellular carcinoma
Hepatocellular carcinoma
Hepatocellular carcinoma
Cholangiocarcinoma of the liver
Acute haemorrhagic necrosis of pancreas
Cystic fibrosis of the pancreas
Cystic fibrosis of the pancreas