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Download - Outcome: Meaningful (~30%) Pain Improvement...Neuropathic Pain: Pharmacotherapy Treatment Outcome: Meaningful (~30%) Pain Improvement Ordered by decreasing estimated efficacy Limitations

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Page 1: Outcome: Meaningful (~30%) Pain Improvement...Neuropathic Pain: Pharmacotherapy Treatment Outcome: Meaningful (~30%) Pain Improvement Ordered by decreasing estimated efficacy Limitations

NeuropathicPain:PharmacotherapyTreatment

Outcome:Meaningful(~30%)PainImprovementOrderedbydecreasingestimatedefficacy

Limitations1. Basedonindirect

comparisons.2. Timeframe~4to

12weeks.3. Detailsonmethods

availableinonlinesupplement.

Amitriptyline

Venlafaxine

Gabapentin

Cannabinoids

25Improvewithtreatment

25Improvewithplaceboornotreatment

50Noimprovement

17Improvewithtreatment

25Improvewithplaceboornotreatment

58Noimprovement

15Improvewithtreatment

25Improvewithplaceboornotreatment

60Noimprovement

9Improvewithtreatment

25Improvewithplaceboornotreatment

66Noimprovement

HighDoseOpioids*

*60-110mgoralmorphineperday

Pregabalin

Duloxetine

18Improvewithtreatment

25Improvewithplaceboornotreatment

57Noimprovement

16Improvewithtreatment

25Improvewithplaceboornotreatment

59Noimprovement

13Improvewithtreatment

25Improvewithplaceboornotreatment

62Noimprovement

Improvewithtreatment

Improvewithplaceboornotreatment

Noimprovement

2018

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