Download - Metabolic Syndrome at Uisu
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Metabolic Syndrome
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The Metabolic Syndrome
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Metabolic syndrome is a name for a groupof risk factors of metabolic origin that occurtogether and increase the risk for
cardiovascular disease and type 2 diabetes.
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Prevalence of Metabolic Syndrome
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24% of whole population
34% of adult population
40% of people > 60 years
80% of patients with type 2 diabetes
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Significance of Metabolic Syndrome
People with metabolic syndrome are 2xas likely todie from CVD and 3xas likely to have a heart attack
or stroke
People with metabolic syndrome have a 5xgreaterrisk of developing type 2 diabetes
Up to 80% of the 200 million people with diabetesglobally will die of cardiovascular disease
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Men Women
n=5,127
Triglyceride Level, mg/dL
50 100 150 200 250 300 350 400
RelativeRisk
0
0.5
1
1.5
2
2.5
3
Castelli WP. Epidemiology of triglycerides: a view from Framingham American Journal of Cardiology.1992;70:3H-9H.
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0,0
1,0
2,0
3,0
100 160 220 8565
4525
LDL-C (mg/dL)
RiskofCHD
Gordon T, Castelli WP, Hjortland MC, Kannel WB, Dawber TR. High density lipoprotein as a protective factor againstcoronary heart disease. The Framingham Study.American Journal of Medicine. 1977;62:707-14.
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Mechanism of Metabolic Syndrome
Si d t b l ik
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Faktor risiko Kadar definisi
Obesitas abdominalPriaWanita
Lingkar pinggang>102 cm (>40 in)>88 cm (>35 in)
Trigliserida 150 mg/dL (1.7 mmol/L)
HDL cholesterol
PriaWanita
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Obesitas sentralLingkar pinggang - Tergantung etnik*
- untuk Eropa: Pria 94 cm
Wanita 80 cm
Ditambah dua dari berikut:
Kenaikan Trigliserida 150mg/dL (1.7mmol/L)Atau sedang dalam pengobatan
Kolesterol HDL rendah
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Managing the Metabolic Syndrome
Reduce the risk for cardiovascular disease and type 2 diabetes
- Lifestyle Risk factors
- Metabolic risk factors
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Examples of Lifestyle Modifications
Low glycemic index foods (vegetables, broccoli, cabbage, cauliflower, cucumber)
Higher fish intake
Higher consumption of vegetables
Mediterranean-style diet (increased consumption of who grains, fruits, vegetables, nuts,
and olive oil)
A lifestyle of 10% fat whole foods vegetarian diet, aerobic exercise, stress
management, training, smoking cessation, group psychosocial support
The DASH (Dietary Approaches to Stop Hypertension) eating plan (reduced calories
and increased consumption of fruit, vegetables, low-fat dairy, and whole grains and
lower in saturated fat, total fat, and cholesterol intake restricted to 2,400 mg NA)
Low fat intake and increased physical activity
Aerobic exercise
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Mediterranean Diet Pyramid
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Examples of Moderate Physical Activity
Gardening for 30-45 minutes
Raking leaves for 30 minutes
Walking 3 kms in 30 minutes
Stair walking for 15 minutes
Wheeling self in wheelchair for 30-40 minutes
Bicycling8 kms in 30 minutes
Water Aerobics for 30 minutes
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Only YOU can take care of yourself!
MAKE good choices!
TEACH good choices!