Download - Mbs6
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MBS-6
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How did it come about?
• Charlotte’s virus• Jisel, Chula, and Clostridium botulinum• Transmission of virus• Specialized transduction to
Mo’s cleavage plateSpecialized Transduction. Digital image. Microbiology - MCB 2010. Teresa G. Fischer, 2010. Web. 24 Apr. 2012. <http://faculty.irsc.edu/FACULTY/TFischer/micro%20resources.htm>.
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The story of Patient 0
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The New Gene
• Keyboard habitat• Easily contracted• New gene: blocks release
of Acetylcholine at neuromuscular junctions• Paralysis-victims often
found using Facebook
Acetylcholine. Digital image. Pharmacology. 9 Mar. 2012. Web. 24 Apr. 2012. <http://pharmacology-notes-free.blogspot.com/2012/03/acetylcholine.html>.
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Signs and Symptoms
• Upper respiratory complications– Congestion– Coughing– Sneezing
• Muscle and joint aches– Focused around the neck and shoulder area
• Fever• Carpal tunnel• Fatigue
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Public Health Risk/Prevention
• Shorten social network site exposure• Only add/accept people you know– Stranger danger
• Wash hands frequently• Take walks outdoors– At least 20mins
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Morbidity versus Mortality32,122 Infections
97 Deaths
0.3% of those infected are expected to die from MBS-6
99.7% of those infected are expected to make a full recovery
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At Risk PopulationsCollege Educated Women in California
Number of Deaths by Education Level
9
42
24
58
0
10
20
30
40
50
60
70
# of deaths
Education Level
Number of Deaths
no response
some high school
high school grad
some college
college grad
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At Risk Populationsnumber of deaths by sex
female77%
male23%
femalemale
Women were almost 3
times more likely to die
from MBS-6!!
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At Risk PopulationsNumber of Deaths
80%
2%
1%
2%
3%
1%
2%
1%
1%
1%
3%
1%
2%
CaliforniaColorado`EnglandFloridaHawaiiMarylandMexicoMichiganNew JerseyPakistanTexasWashingtonUnreported
80% of Those
Who Died from
MBS-6 Lived
in
California !!!!
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MBS-6 A global disease
Countries affected:United States, UK, Pakistan, Mexico, New Zealand, Australia
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MBS-6 Deaths per Day
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MBS-6 R0
•R0 = Basic reproduction number
•R0 = (βΝ)/Υ• R0 = (Contact rate x Total Population) / Average infection
period
•Initial estimate: R0 < 3
•Actual: R0 > 5
•R0 > 1 is considered an epidemic
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• Vaccination–Herd immunity
• Inactivation of toxic producing cells–Blocking hemmaglutinin and neuraminadase
Possible cures and vaccines?
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• Anticholinergenic agent• Reversible agents–Nicotine–caffeine
Immediate response