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Introduction to theKnowledge Discovery DepartmentInstitute for Infocomm Research
Limsoon WongDeputy Executive Director (Research)
I2R: Imagination to reality
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I2R
• mission: Advance Infocomm Technology to benefit humanity and create prosperity for S’pore
• core values: Dedication to excellence, passion for innovation, integrity & respect
• size: 350 RSEs
SERCBMRC
IHPCDSI
IMRE
SIMTECH
IME
ICES
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EDB-iDA ICT Cluster Map
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• Next Gen IP• End-to-end QoS• Mobile Middleware• Mobile Adhoc Networks• Mobile Sensor Networks
Organization
I2R
Communications & DevicesServices & Applications Media
Media Processing
Human ComputerInteraction
Media Semantics
Infocomm Security
E-Service Infrastructure
Knowledge Discovery
Radio Systems Networking LightwaveEmbedded Systems
Digital Wireless
• Mutimedia Signal Processing
• Noise Reduction
• Media Adaptation• Mixed Media Mining• Natural Language Synergy
• Pervasive Media
• Perceptual Human Media
• Speech & Dialogue• Biometrics
• Cryptography• Network security• Information security
• Service Composition
• Service creation• Data-in-Network• Connected Home• Secure Filesystem/ DBMS
• Modem Technology• Multiple Access• Smart Antenna Array Systems
• Network Design• WDM Systems• Fibre Technology
• Terminal• Software Defined Radio
• Transceiver system• Antenna• Radio Over Fiber• UWB
• Knowledge Extraction
• Decision Systems• Discovery Systems
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Information Security
E-services Infrastructure
Knowledge Discovery
Services & Applications
Knowledge ExtractionData fusion from sensors, knowledge extraction technologies. Applications in functional genomics & gene regulatory networks
Decision SystemsData Mining technologies. Applications in clinical data analysis and protein network analysis
Discovery SystemsData cleansing, modeling & knowledge management technologies. Applications in immunoinformatics and venominformatics
Service CreationPolicy-based framework for creating/managing application, storage and network services
Data-in-Network High-speed data cache and IPC on optical network
Service Composition Tech for consumers to create personalized services from component e-services
Connected HomeReference design for an OSGi compliant residential gateway
CryptographyCryptographic techniques for privacy protection, high-speed encryption, group digital signatures and new public key infrastructure
Information SecurityTechniques for privacy protection, peer-to-peer system security and media security
Network SecurityWireless network security, intrusion detection and technology to trace attackers
Secure FilesystemSteganographic and reliable file systems/DBMSs on externally managed platforms
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IntegrationTechnology(Kleisli)
Cleansing & Warehousing (FIMM)
MHC-PeptideBinding(PREDICT)
Protein InteractionsExtraction (PIES)
Gene Expression & Medical RecordDatamining (PCL)
Gene FeatureRecognition (Dragon)
VenomInformatics
1994 19981996 2000 2002
8 years of bioinformaticsR&D in Singapore
ISS KRDL LIT/I2R
GeneticXchange
MolecularConnections
Biobase
History
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Directions
Knowledge Extraction• gene regulatory network• endocrinology info system
Discovery Systems• immunoinformatics• venominformatics
Decision Systems• clinical data analysis• protein interaction
network
Technologies for• data mining• data fusion• data cleansing• data modeling• knowledge extraction• knowledge management
Advance data mining technologies in decision systems for complexproblems
Translate inspiration from biological systems into advancement in life and computing sciences
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Decision Systems Lab Highlight
PCL Technology• Machine learning of
emerging patterns• Rules learned by
computers easily understood by doctors
• High accuracy
Yeoh et al.Cancer Cell 1, 133-143, 2002
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FANTOM2 ConsortiumNature 420, 563-573, 2002
Discovery Systems Lab Highlight
• Brusic et al. Cytokine-related genes identi-fied from the RIKEN full-length mouse cDNA dataset. Genome Res. (in press)
• Silva et al. Identifica-tion of novel human disease-related gene candidates from the RIKEN full-length mouse cDNA dataset. Genome Res. (in press)
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KE Lab Highlight
• Dragon Promoter Finder and Dragon Gene Start Finder
• Very high accuracy, order of magnitude improvement
• Licensed to Biobase, integrated with TRANSPLORER and TRANSFAC
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Qualification
• 18 full-time staff (9 PhD, 6MSc, and 3 BSc) and 10-20 students at any time
• Our faculty holds adjunct professorial positions (SANBI, Univ. of Canberra, NUS, and NTU)
• During the last two years 8 MSc students graduated under our supervision
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Professional Activities
•Journals: 3 chief editorial roles, and 9 editorial board memberships
•International Conferences (last 5 years): 4 conference chairs, and more than 40 program committee roles, 10 keynote lectures, and dozens of plenary talks
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Track Record
•Publications (last 5 years): More than 100 in last 5 years, many in top journals (e.g. Nature, PNAS, Cancer Cell, JACM) and top conferences.
•Patents (last 5 years): 1 granted and 6 pending
•Commercialization (last 5 years): 2 international start-ups and one software licensed
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People
Decision SystemsHead: Dr. See-Kiong NgPI: A/Prof. Limsoon Wong, Dr. Jinyan Li Staff: Huiqing Liu, Zhuo Zhang, Soon-Heng TanPost Doc: Dr. Shaowu Meng
Discovery Systems Head: A/Prof. Vladimir BrusicStaff: Judice Koh, Guanglan Zhang, Seng Hong SeahPost Doc: Dr. Rekha Pillai
Knowledge ExtractionHead: Prof. Vladimir B. BajicStaff: Hao Han, SPT Krishnan, Allen Chong, Sin Lam TanPost Doc: Dr. Suisheng Tang
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Here they are...