Download - Free Testosterone Video Slides

8/8/2019 Free Testosterone Video Slides

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Free TestosteroneDicken Weatherby, N.D.

http://www.FunctionalMedicineUniversity.com Sequoia Education Systems, Inc 1

Free TestosteroneFree Testosterone

Factors That AffectFactors That Affect

Testosterone LevelsTestosterone Levels Estrogen and

Increased aromatase levels

Obesity

Increased Sex Hormone Binding Globulin(SHBG) production


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Low Testosterone Levels in MenLow Testosterone Levels in Men

Diminished libido and erectile dysfunction

Metabolic syndrome: Loss of muscle toneand increased abdominal fat

Low bone density

Depression

Alzheimers disease

Low Male Hormone LevelsLow Male Hormone Levels

Increase Risk of Early DeathIncrease Risk of Early DeathRelationship between low levels of analbolic

hormones and 6-year mortality in older men:the aging in the Chianti are (InCHIANTI) study

Maggio M, Laurenti F, Ceda GP, et al. Arch InternMed. 2007 November 12:167(20):2249-54

Conclusion:

Having multiple hormone deficiencies ratherthan a deficiency in a single anabolkic hormoneis a robust biomarker of health status in olderpersons.


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Low testosterone as a majorLow testosterone as a major

cardiac risk factorcardiac risk factor

Age, HDL levels, and free testosterone

Increased risk of stroke

Heart failure

Increased glycation

Testosterone- an increased risk ofprostate cancer?

Importance of testosterone inImportance of testosterone in

WomenWomen

Muscle strength

Bone mass

Sexual function

Mood

Body composition


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Measuring FreeMeasuring Free

TestosteroneTestosterone

Free TestosteroneFree Testosterone--

LabcorpLabcorp Reference RangesReference Ranges Normal reference range intervals for men:

20 - 29 years old 9.3 - 26.5 pg/ml

30 - 39 years old 8.7 - 25.1 pg/ml

40 - 49 years old 6.8 - 21.5 pg/ml

50 - 59 years old 7.2 - 24.0 pg/ml

60+ years old 6.6 - 18.1 pg/ml

Women: 0 2.2 pg/ml

Optimal reference range:Men: 15 26.5 pg/mL

Women: 1.4 2.2 pg/mL


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Free TestosteroneFree Testosterone--

Quest Reference RangesQuest Reference Ranges

Normal reference range intervals formen:

20 60+ years old 50 - 210 pg/ml

Optimal reference range:

Men: 150 210 pg/mL

The Different Analytical MethodsThe Different Analytical Methods

% of free by UF or ETD1.0 2.7%

UF or ETD50 210 pg/mL

UF or ETD5 21 ng/dL

%FWRA12.3 63%

FWRA66 417 ng/dL

Test TypeMale Ref. Range


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What about total testosterone?What about total testosterone?

Normal reference ranges: 241 827nanograms/dl

Optimal levels: 500 827 nanograms/dl

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