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Founders
With the support of
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2
Letters of intent
Individual quotation, then selection by the SAB Validation by the Bureau
Full Application
Individual quotation, then selection by the SAB
Proposal to the bureau
Selection and validation by Executive Comittee
Selection process
40
15
10
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3
Selected Projects
Comparison of bioassay, Scrapie Cell-Assay and Protein Misfolding Cycle Assay performances for detection of endogenous Prion in sheep blood
Principal Investigator: O. Andreoletti (INRA-ENVT, Toulouse, France)
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4
Selected Projects
Probing the chemistry and conformational change underlying autocatalytic self-propagation of misfolded prion protein
Principal Investigator: M. Beekes (Robert Koch Institute, Berlin, Germany)
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5
Selected Projects
Optimisation, evaluation and validation of a PMCA-based confirmatory screening assay to detect prions in human blood. A French and British Collaborative Study
Principal Investigators: J. Coste (EFS-PM, Montpellier, France) M. Jones (SNBTS, Edinburgh, UK)
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6
Selected Projects
Assessment of prion infectivity in blood in primate and sheep models, and evaluation of removal processes (extension 2009)
Principal Investigator: D. Dernis (EFS-Nord, Lille, France)
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7
Selected Projects
Infectivity titrations of blood components from chimpanzees infected with the agent of Gerstmann-Sträussler-Scheinker Syndrome in mice and comparison of sensitivity of mouse bioassays
Principal Investigator: L. Gregori (FDA, USA)
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8
Selected Projects
Evaluation of cold atmospheric plasma to decontaminate surgical instrument surfaces and eliminate prion infectivity
Principal Investigators: C. W. Keevil (Southampton University, UK) R. Hervé (Southampton University, UK)
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9
Selected Projects
An assessment of the relevancy of sheep and mice animal model for blood safety investigation
Principal Investigator: C. Lacroux (INRA-ENVT, Toulouse, France)
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10
Selected Projects
Detection of PrPSc (a biomarker for TSE infection) in blood using QUIC shake technology: validation of in vitro studies with infectivity models
Principal Investigators: J. C. Manson (The Roslin Institute, UK) S. MacCutcheon (The Roslin Institute, UK)
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11
Selected Projects
Elucidation of the misfolding process… Insights into a preamyloid state by selectively trapping prion proteins in oligomeric forms
Principal Investigator: J. Torrent (INSERM, Montpellier, France)
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12
Selected Projects
Risk assessment of Insoluble PrP from normal human brains
Principal Investigator: W.Q. Zou (Case Western Reserve University, Cleveland, USA)