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Page 1: ChemInform Abstract: Amidine Protection for Solution Phase Library Synthesis

1999 carboxylic acid derivatives

carboxylic acid derivatives (naphthalene compounds)Q 0950

36 - 117Amidine Protection for Solution Phase Library Synthesis. — Theapplication of the Moz-protecting group for N-protection of the amidinonaphthol(I) is described. The facile introduction by the mixed carbonate (II) and themildness of deprotection makes this group suited for multiparallel solution phasesynthesis of substituted benzamidines. — (BAILEY, CHRISTINE; BAKER,EMMA; HAYLER, JUDY; KANE, PETER; Tetrahedron Lett. 40 (1999) 26,4847-4850; NOVARTIS Horsham Res. Cent., Horsham, West Sussex RH124AB, UK; EN)

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