Upload File

cheminform abstract: amidine protection for solution phase library synthesis

  • Home
  • Documents
  • ChemInform Abstract: Amidine Protection for Solution Phase Library Synthesis
1
1999 carboxylic acid derivatives carboxylic acid derivatives (naphthalene compounds) Q 0950 36 - 117 Amidine Protection for Solution Phase Library Synthesis. — The application of the Moz-protecting group for N-protection of the amidinonaphthol (I) is described. The facile introduction by the mixed carbonate (II) and the mildness of deprotection makes this group suited for multiparallel solution phase synthesis of substituted benzamidines. — (BAILEY, CHRISTINE; BAKER, EMMA; HAYLER, JUDY; KANE, PETER; Tetrahedron Lett. 40 (1999) 26, 4847-4850; NOVARTIS Horsham Res. Cent., Horsham, West Sussex RH12 4AB, UK; EN) 1

Upload: christine-bailey

Post on 06-Jun-2016

220 views

Category:

Documents


6 download

Report

TRANSCRIPT

Page 1: ChemInform Abstract: Amidine Protection for Solution Phase Library Synthesis

1999 carboxylic acid derivatives

carboxylic acid derivatives (naphthalene compounds)Q 0950

36 - 117Amidine Protection for Solution Phase Library Synthesis. — Theapplication of the Moz-protecting group for N-protection of the amidinonaphthol(I) is described. The facile introduction by the mixed carbonate (II) and themildness of deprotection makes this group suited for multiparallel solution phasesynthesis of substituted benzamidines. — (BAILEY, CHRISTINE; BAKER,EMMA; HAYLER, JUDY; KANE, PETER; Tetrahedron Lett. 40 (1999) 26,4847-4850; NOVARTIS Horsham Res. Cent., Horsham, West Sussex RH124AB, UK; EN)

1

spyrmsd: symmetry-corrected RMSD calculations in Python · 2020. 8. 31. · Meli and Biggin J Cheminform Page 3 of 7 usingtheNewton-Raphsonmethod[7]startingfromthe initialguess (GA

The Trypanocidal Activity of Amidine Compounds Does Not Correlate with Their Binding Affinity to

Research Article Amidine Sulfonamides and Benzene Sulfonamides ...downloads.hindawi.com/journals/jchem/2015/524056.pdf · Research Article Amidine Sulfonamides and Benzene Sulfonamides:

Amidine: Structure , Reactivity and Complexation Behavioursphinxsai.com/pdf/jct_Ap_Ju_09/CT=25 Bibhesh Kumar Singh (250-264… · as intermediates in the synthesis of some metallocyclic

RESEARCHARTICLE LargescalecomparisonofQSAR … · 2020. 3. 19. · Boscet al. J Cheminform Page3of16 Dta preparation Compoundstructureswereextractedfromthedatabase inSMILESformatandusingRDKit(version2017_09_01)

CARBON DIOXIDE CAPTURE BY TERTIARY AMIDINE FUNCTIONAL ...d-scholarship.pitt.edu/6624/1/GattusoSA_04_06_2007.pdf · CARBON DIOXIDE CAPTURE BY TERTIARY AMIDINE FUNCTIONAL ADSORBENTS

New Reactions with N-Heterocyclic Carbene Boranes and Amidine …d-scholarship.pitt.edu/33821/1/trmcfadden_etd_2018_1.pdf · 2018. 3. 23. · New Reactions with N-Heterocyclic Carbene

Switchable ionic liquids for biomass treatmentumu.diva-portal.org/smash/get/diva2:943265/FULLTEXT01.pdf · The typical superbases for SILs can be either amidine derivatives, such

Silver-Catalyzed [3+2+1] Annulation of Aryl Amidines with · PDF fileGeneral procedure for the synthesis of 2,4 ‐ ... In a Schlenk tube, the mixture of aryl amidine 1 (0.4 mmol),

Filtered circular fingerprints improve either prediction ... · Gütlein and Kramer J Cheminform () DOI 10.1186/s13321-016-0173-z RESEARCH ARTICLE Filtered circular fingerprints improve

Design and synthesis of amidine-type peptide bond …repository.kulib.kyoto-u.ac.jp/dspace/bitstream/2433/...Title Design and synthesis of amidine-type peptide bond isosteres: application

METHODOLOGY Molecularstructuresenumeration and ......Koch et al. J Cheminform Page5of17 changing4bonds,sinceweaimtondminimaltransfor - mations.Letuscall a 13 and a 24 thetwofixedbonds,with

ChemDoodle Web Components: HTML5 toolkit for …...Burger. J Cheminform DOI 10.1186/s13321-015-0085-3 REVIEW ChemDoodle Web Components: HTML5 toolkit for chemical graphics, interfaces,

H. J. Chowdhery studies on the subfamily …shodhganga.inflibnet.ac.in/bitstream/10603/81228/7/07...involves conjugate addition of the amidine nitrogen to the malononitrile followed

GPURFSCREEN: a GPU based virtual screening tool …people.cse.nitc.ac.in/jayaraj/files/gpurfscreen...Jayaraj et al. J Cheminform DOI 10.1186/s13321-016-0124-8 SOFTWARE GPURFSCREEN:

Database fingerprint (DFP): an approach to represent ... · Fernández‑de Gortari et al. J Cheminform DOI 10.1186/s13321‑017‑0195‑1 PRELIMINARY COMMUNICATION Database fingerprint

Consensus Diversity Plots: a global diversity analysis of ......González‑Medina et al. J Cheminform 01 3 DOI 10.1186/s13321‑016‑0176‑9 METHODOLOGY Consensus Diversity Plots:

BIOINFORMATICS Review …“.Jónsdóttir et al. Fig. 1. Number of papers in PubMed 1992–2004 containing the keywords ‘bioinformatics’ (top left), ‘chemoinformatics’ or ‘cheminform-atics’,

ChemDoodle Web Components: HTML5 toolkit for chemical graphics, interfaces… · 2017-04-10 · Burger. J Cheminform DOI 10.1186/s13321-015-0085-3 REVIEW ChemDoodle Web Components:

Jessica Hawley PROTEIN SYNTHESIS. Protein Synthesis Protein Synthesis PROTEIN SYNTHESIS

Synergy Maps: exploring compound combinations using ......Lewis et al. J Cheminform DOI 10.1186/s13321-015-0090-6 SOFTWARE Synergy Maps: exploring compound combinations using network-based

ChemInform RxnFinder

New Palacký University in Olomouc Faculty of Science Department … · 2013. 8. 21. · 4.1 Replacement of thiourea with an amidine group in a monofunctional ... anticancer effective

CHAPTER-II - Shodhgangashodhganga.inflibnet.ac.in/bitstream/10603/2211/11/11_chapter 2.pdf · Synthesis of pyrimidines commonly involves cyclocondensation reactions of amidine, guanidine,

Statistical principle-based approach for gene and protein ... · Lai et al. J Cheminform Page 2 of 9 tobiologicaldatabaserecords.Intheabovecases,“A2A” isasubtypeof“adenosinereceptor”.erefore“A2A

Rebecca Lucy MelenActivation: A New Chapter in the Chemistry of Frustrated Lewis Pairs”, Angew. Chem. Int. ... “Amidine functionalized phosphines: tuneable ligands for transition

Open Access Programming langage in chemiy: a eie of HTML5 ... · Theien J Cheminform Page 3 of 19 HTML5 econtentweviewontheInternetismadepossiblebya unionofseveraltechnologies,mainlyHypertextMarkup

Design and Synthesis of Amidine-type Peptide Bond · PDF fileS1 Supplementary Information Design and Synthesis of Amidine-type Peptide Bond Isostere: Application of Nitrile Oxide Derivatives

phase synthesis Peptidines: Glycine-amidine-based oligomers · PDF filePeptidines: Glycine-amidine-based oligomers for solution- and solid-phase synthesis Julian Vastl, Rendy Kartika,

BIOLOGICAL EVALUATIONS OF AMIDINE AND ... EVALUATIONS OF AMIDINE AND AMIDOXIME SUBSTITUTED HETEROCYCLES WITH 1,2,3-TRIAZOLYL SPACER Silvija Maračić,[a] Helena Šimek,[a] Petra Grbčić,[b]

Design and synthesis of amidine-type peptide bond isosteres ...via peptide amidoximes. Results and Discussion Preparation of Amino Acid-derived Nitrile Oxide and the Application to

University of Manchester · Web viewIn summary, reductive amidine-alkene radical cyclisations, involving the intramolecular addition of aminal radicals to simple alkenes, deliver

Synthesis from VHDL 1. Layout synthesis 2. logic synthesis 3. RTL synthesis 4. High Level Synthesis 5. System Synthesis Behavioral synthesis of pieces

METHODOLOGY Ecientiterativevirtualscreening with … · 2018. 3. 1. · Ahmed et al. J Cheminform Page4of8 10contain‘high-scoring’ligands.eunassignedbin3is excludedfromtraining.Figure

RESEARCHARTICLE Assessingtheinformationcontent ......Rodríguez‑Pérezet al. J Cheminform Page6of14 whichyieldedmedianMCCvaluesof0.67(IFP_85) and0.63(EFCP_folded).us,inhibitorswithbinding