Transcript

1999 fused pyrrole derivatives

fused pyrrole derivativesR 0160

23 - 1424’-Hydroxyphenylcarbamates of (3aS)-Eseroline and (3aS)-N(1)-Noreseroline: Potential Metabolites of the Alzheimer’s Anti-cholinesterase Drug Phenserine. — Two novel compounds (I) as likelymetabolites of the Alzheimer drug phenserine are prepared. Both demonstratepotency for cholinesterase inhibitory action. — (YU, QIAN-SHENG; GREIG,NIGEL H.; HOLLOWAY, HAROLD W.; BROSSI, ARNOLD; Heterocycles 50(1999) 1, 95-102; Lab. Cell. Mol. Biol., Natl. Inst. Aging, NIH, Baltimore, MD21224, USA; EN)

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