ChemInform Abstract: 4′-Hydroxyphenylcarbamates of (3aS)-Eseroline and (3aS)-N(1)-Noreseroline: Potential Metabolites of the Alzheimer′s Anticholinesterase Drug Phenserine.

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  • 1999 fused pyrrole derivatives

    fused pyrrole derivativesR 0160

    23 - 1424-Hydroxyphenylcarbamates of (3aS)-Eseroline and (3aS)-N(1)-Noreseroline: Potential Metabolites of the Alzheimers Anti-cholinesterase Drug Phenserine. Two novel compounds (I) as likelymetabolites of the Alzheimer drug phenserine are prepared. Both demonstratepotency for cholinesterase inhibitory action. (YU, QIAN-SHENG; GREIG,NIGEL H.; HOLLOWAY, HAROLD W.; BROSSI, ARNOLD; Heterocycles 50(1999) 1, 95-102; Lab. Cell. Mol. Biol., Natl. Inst. Aging, NIH, Baltimore, MD21224, USA; EN)

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