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2nd WORLD CONGRESS ON MATERNAL FETAL NEONATAL MEDICINE
SCIENTIFIC PROGRAMME
Thursday, 4th April 2019
PRE-CONGRESS POSTGRADUATE COURSES
FLEMING ROOM
09.00 – 16.30 COURSE 1: THE FIRST TRIMESTER PRENATAL TESTING
Course Directors: Kypros Nicolaides, UK; Katia Bilardo, the Netherlands;
Liona Poon, Hong Kong
ANEUPLOIDIES:
09.00 - 09.30 Universal cfDNA testing by targeted approach
Jacques Jani, Belgium
09.30 - 10.00 Universal cfDNA testing by genome wide approach
Mireille Bekker, the Netherlands
10.00 - 10.30 Abnormalities missed because of NIPT
Mark Evans, USA
10:30 - 11.00 Contingent cfDNA testing
Kypros Nicolaides, UK
11.00 – 11.10 Discussion
11.10 - 11.30 BREAK
STRUCTURAL ANOMALIES:
11.30 - 12.00 The first trimester anomaly scan
Katia Bilardo, the Netherlands
12.00 - 12.30 The first trimester fetal echo
Vita Zidere, UK
12.30 - 13.10 LUNCH BREAK
PREECLAMPSIA:
13:10 - 13:40 How best should we screen for pre-eclampsia?
Liona Poon, Hong Kong
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GROWTH ABNORMALITIES/STILLBIRTH:
13.40 - 14.10 Do we have the right tools to detect growth abnormalities and stillbirth?
Ranjt Akolekar, UK
PRETERM BIRTH:
14.10 - 14.40 New advances for early prediction of preterm birth
Eduardo Fonseca, Brazil
TWINS:
14.40 - 15.10 How to avoid complications in twins?
Asma Khalil, UK
CLOSING:
15.10 - 15.40 Inverting the pyramid: where are we heading?
Kypros Nicolaides, UK
15.40 - 16.00 Discussion and end of the course
WHITTLE ROOM
09.00 – 13.20 COURSE 2: PRETERM NEWBORN RESUSCITATION
Course Directors: Eduardo Bancalari, USA; Ola D. Saugstad, Norway;
Christian Poets, Germany
09.00 - 09.20 Surfactant delivery: When, how?
David Sweet, UK
09.20 - 09.40 Current recommendations on the use of oxygen in the delivery room
Ola D. Saugstad, Norway
09.40 - 10.00 Are we using the best tools for respiratory support in the delivery room?
Eduardo Bancalari, USA
10.00 - 10.20 Strategies to protect the immature brain after birth
Pierre Gressens, France
10.20 - 10.40 Discussion
10.40 - 11.10 BREAK
11.10 - 11.30 Perinatal infection and neonatal adaptation
Alan Jobe, USA
11.30 - 11.50 Bonding the preterm infant in the delivery room
Christian Poets, Germany
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11.50 - 12.00 Discussion
12.00 - 12.20 Timing of cord clamping, does it make a difference?
Haresh Kirpalani, Canada
12.20 - 12.40 Interventions to avoid early neonatal hypoglycemia
Umberto Simeoni, Switzerland
12.40 - 13.00 Initial respiratory support in the delivery room
Peter Davis, Australia
13.00 - 13.20 Discussion
GUILD ROOM
09.00 - 12.30 COURSE 3: GENETICS, EPIGENETICS AND THE DEVELOPMENTAL ORIGINS OF ADULT
HEALTH (in cooperation with DOhAD International Society)
Course Directors: Lucilla Poston, UK, Mark Hanson, UK
09.00 - 09.20 Introduction: DOHaD and maternal fetal medicine
Lucilla Poston, UK
09.20 - 09.50 Methods in epigenetics research
Lucia Migliore, Italy
09.50 - 10.10 Multidisciplinary approach and DOHaD perspective on kidney size and function
evaluation in the perinatal period
Benito Cappuccini, Italy
10.10 - 10.20 Discussion
10.20 - 10.40 BREAK
10.40 - 11.10 Maternal emotional health and offspring neurodevelopment
Yap Seng Chong, Singapore
11.10 - 11.40 Epigenetics and environmental toxicants in development
Paolo Vineis, UK
11.40 - 12.00 Paternal epigenetic effects on development
Adam Watkins, UK
12.00 - 12.30 Discussion
12.30 – 13.00 Conclusion: DOHaD and global health
Lucilla Poston, UK
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WHITTLE ROOM
13.40 – 17.00 COURSE 4: INFECTIONS IN THE PRENATAL AND NEONATAL PERIOD
Course Directors: Alan Jobe, USA; Paolo Manzoni, Italy;
Laurent Mandelbrot, France
13.40 – 14.00 Epidemiology and microbiology of Vertical sepsis in neonates in the era of
universal IAP for GBS
Ranjan Pejaver, India
14.00 – 14.20 Neonatal sepsis and possible approaches involving use of stem cells:
state of the art
Bernard Thebaud, Canada
14.20 – 14.40 Neonatal infections and water delivery: state of the art
Stefano Uccella, Italy
14.40 – 15.00 Perinatal fungal infections in the NICU
Omer Erdeve, Turkey
15.00 – 15.20 Intrapartum antibiotics and neonatal microbioma: which implication?
Josef Neu, USA
15.20 – 15.40 Update on perinatal CMV prevention and management
Giovanni Nigro, Italy
15.40 – 16.00 Transitioning from fetal to neonatal immune status: which are the main clinical
implications?
Jim Wynn, USA
16.00 – 16.20 Clinical and animal models of chorioamnionitis: latest updates
Suhas Kallapur, USA
16.20 – 17.00 Discussion
WESLEY ROOM
09.00 – 16.30 COURSE 5: SAFE MOTHERHOOD AND NEWBORN HEALTH
(JOINTLY ORGANISED WITH FIGO)
Course Directors: Maria Fernanda Escobar, Colombia;
Gerard H. A. Visser, the Netherlands; Diogo Ayres-Do-Campos, Portugal
09.00 - 09.10 Opening
Gerard H. A. Visser, the Netherlands
SESSION 1: OBSTETRIC EMERGENCIES
Chair: Maria Fernanda Escobar, Colombia
09.10 - 09-30 Prevention of PPH: new evidence
Daniel Surbek, Switzerland
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09.30 - 09.50 Update in the treatment of PPH
Anton Mikhailov, Russia
09.50 - 10.30 Diagnosis and management of maternal sepsis
Maria Fernanda Escobar, Colombia
10.30 - 11.00 Discussion
11.00 - 11.30 BREAK
SESSION 2: OBSTETRICS IN LOW-RESOURCE COUNTRIES
Chair: William Stones, Malawi
11.30 - 11.50 Reintroduction of vaginal instrumental deliveries,
Jan Van Roosmalen, the Netherlands
11.50 - 12.10 Fetal monitoring in low-resource countries
Jan Van Roosmalen, the Netherlands
12.10 - 12.30 Affordable and low-maintenance obstetric devices
Diogo Ayres-de-Campos, Portugal
12.30 - 13.00 Discussion
13.00 - 14.00 LUNCH BREAK
SESSION 3: TOO MANY, TOO RISKY?
Chair: Gerard H. A. Visser, the Netherlands; Diogo Ayres-de-Campos, Portugal
14.00 - 14.30 Excessive use of C-sections
Gerard H. A. Visser, the Netherlands
14.30 - 14.50 Excessive number of vaginal examinations during labour?
Diogo Ayres-de-Campos, Portugal
14.50 - 15.10 How long can we allow the second stage of labour to last?
Dan Farine, Canada
15.10 - 15.30 Role of fetal-maternal Doppler velocimetry at term
Irene Giardina, Italy
15.30 - 15.50 Excessive use of episiotomies
Anwar Nassar, Lebanon
15.50 - 16.10 Discussion
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16.10 - 16.40 FIGO minimal staffing recommendations for maternity hospitals
William Stones, Malawi
16.40 - 17.00 Discussion
ST JAMES ROOM
09.00 – 15.30 COURSE 6: PLACENTA ACRRETA SPECTRUM DISORDERS (PAS): MAKING DECISIONS
Course Directors: Josè M. Palacios Jaraquemada, Argentina;
Corinne Hubinont, Belgium; Mohamed Momtaz, Egypt
09.00 - 09.10 Introduction
José M. Palacios-Jaraquemada, Argentina
09.10 - 09.30 Is it really possible to reduce the incidence of PAS?
José M. Palacios-Jaraquemada, Argentina
09.3 0- 09.50 Emergency versus elective management for PAS
Mohamed Momtaz, Egypt
09.50 - 10.10 Iliac internal vascular control complications
José M. Palacios-Jaraquemada, Argentina
10.10 - 10.20 BREAK
10.20-10.40 Management protocol in severe postpartum hemorrhage
Daniel Surbek, Switzerland
10.40 - 11.00 Standardized surgical technique of hysterectomy for PAS
Mohamed Momtaz, Egypt
11.00 - 11.20 Why some PAS locations are associated with high morbidity and mortality?
José M. Palacios-Jaraquemada, Argentina
11.20 - 12.00 Discussion and home messages
José M. Palacios-Jaraquemada, Argentina
12.00 - 13.00 LUNCH BREAK
13.00 - 13.20 How different is a premature newborn at 34 or 36/7 weeks?
Ola D. Saugstad, Norway
13.20 - 13.40 Management of PAS: Expectant or immediate treatment
Corinne Hubinont, Belgium
13.40 - 14.00 PAS in low resources settings: What can we do?
Mohamed Momtaz, Egypt
14.00 - 14.20 PAS diagnosis: Are we using the same signs?
Eric Jauniaux, UK
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14.20 - 14.40 Timing of caesarean section according to urgency. Rupture, massive bleeding
Aris Antsaklis, Greece
14.40 - 15.00 News in etiopathology could change our concept of prophylactic uterine
repair?
Eric Jauniaux, UK
15.00 - 15.30 Discussion and home messages
Mohamed Momtaz, Egypt
VICTORIA ROOM
09.00 – 16.30 COURSE 7: PRETERM BIRTH: PREVENTION AND PREDICTION
A PREIS SCHOOL ACADEMY COURSE
Course Directors: Eduardo Fonseca, Brazil; Bo Jacobsson, Sweden
09.00 – 09.10 General introduction
Course Directors
09.10 – 9.30 Historical and clinical risk factors (history of preterm birth, body mass index,
life style, interpregnancy interval)
Bo Jacobsson, Sweden
09.30 – 09.50 The genetics of preterm birth
Joe Leigh Simpson, USA
09.50 – 10.10 Cervical ultrasound as a screening method for preterm birth
Eduardo Fonseca, Brazil
10.10 - 10.30 New imaging modalities for cervical length for the prediction of preterm birth
Sonia Hassan, USA
10.30 - 10.50 Biomarkers of preterm delivery in first and second trimester in asymptomatic
women: an update
Andrew Shennan, UK
10.50 - 11.00 Discussion
11.00 – 11.20 BREAK
11.20 – 11.50 Genetics of gestational age and preterm delivery: an update
Luis J. Muglia, USA
11.50 – 12.20 Prediction of preterm birth in the first trimester
Liona Poon, Hong Kong
12.20 – 12.30 Discussion
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12.30 – 13.30 LUNCH BREAK
13.30 – 14.00 Vaginal progesterone for the prevention of preterm birth
Roberto Romero, USA
14.00 – 14.20 Aspirin to all or to selected population
Marion A. de Boer, the Netherlands
14.20 – 14.40 Cerclage for the prevention of preterm birth
Vincenzo Berghella, USA
14.40 – 15.00 Pessary for the prevention of preterm birth
Maria M. Goya Canino, Spain
15.00 – 15.40 Corticosteroides 34 to 36 and rescue doses
Pro: Cynthia Gyamfi Bannermann, USA Con: Gerard H.A. Visser, the Netherlands
15.40 – 16.10 Special Lecture: Preterm labour as syndrome
Roberto Romero, USA
16.10 – 16.30 Discussion and closing remarks
GUILD ROOM
13.30 - 16.30 COURSE 8: TIPS AND TRICKS IN ULTRASOUND AND DOPPLER SCAN IN
PREGNANCY: LIVE SCAN
Course Directors: Graziano Clerici, Italy; Giuseppe Rizzo, Italy
13.30 - 13.35 Introduction to the course
Giuseppe Rizzo, Italy
13.35 - 14.15 Anomaly scan: tips and tricks
Graziano Clerici, Italy
14.15 - 14.45 Fetal anomaly scan: interactive live scan
Graziano Clerici, Italy
14.45 - 15.00 Discussion
15.00 - 15.30 BREAK
15.30 - 16.00 Maternal-fetal hemodynamics: tips and tricks
Giuseppe Rizzo, Italy
16.00 - 16.30 Maternal-fetal hemodynamics: interactive live scan
Graziano Clerici, Italy
16.30 - 16.45 Discussion
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ALBERT ROOM
09.00 - 16.00 COURSE 9 – CRITICALLY ILL OBSTETRICS PATIENTS
Course Director: Daniela Vazquez, Argentina
09.00 – 09.20 Introduction
Daniela Vasquez, Argentina
HYPERTENSIVE DISORDERS
09.20 – 09.50 Definitions and recognition of severity of illness. Presentation of severe forms
of hypertensive disease of pregnancy
Liliana Voto, Argentina
09.50 – 10.10 Initial management of severe preeclampsia to prevent maternal morbidity
and mortality
Luca Marozio, Italy
10.10 – 10.30 Indications for delivery in women with hypertensive disease of pregnancy
Rasha Ahmed Mostafa Kamel, Egypt
10.30 – 10.45 Case presentation
Daniela Vasquez, Argentina
10.45 – 11.00 Discussion & take home message
Daniela Vasquez, Argentina
11.00 – 11.20 BREAK
POSTPARTUM HEMORRHAGE
11.20 – 11.40 Severe postpartum hemorrhage: diagnosis, quantification, and detection of
occult shock
Daniela Vasquez, Argentina
11.40 – 12.00 DIC and pregnancy challenges in diagnosis and treatment
Offer Erez, Israel
12.00 – 12.20 Medical management of severe postpartum hemorrhage
Rasha Ahmed Mostafa Kamel, Egypt
12.20 – 12.40 Surgical management of postpartum hemorrhage
José M. Palacios Jaraquemada, Argentina
12.40 – 13.00 Case presentation, discussion and take home message
José M. Palacios Jaraquemada, Argentina
13.00 – 13.40 LUNCH BREAK
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PUERPERAL SEPSIS
13.40 – 14.00 Diagnosis, classification and causes of puerperal sepsis
Maria Fernanda Escobar, Colombia
14.00 – 14.20 Initial treatment of sepsis: the importance of considering the golden hour.
Daniela Vasquez, Argentina
14.20 – 14.40 Puerperal sepsis: source control and indications for hysterectomy
Maria Fernanda Escobar, Colombia
14.40 – 15.00 Case presentation & take home message
Daniela Vasquez, Argentina
PULMONARY EMBOLISM
15.00 – 15.20 Detection and urgent treatment of pulmonary embolism
Jacky Nizard, France
15.20 – 15.40 What has changed the need for DVT and pulmonary embolism prophylaxis?
Dan Farine, Canada
15.40 – 16.00 Case presentation & take home message
Jacky Nizard, France
16.00 - 16.15 Conclusions
Daniela Vasquez, Argentina
WHITTLE ROOM
18.00 – 19.30 OPENING & WELCOME RECEPTION
OPENING REMARKS
The Organisers
KEY NOTE ADDRESSES
The artificial placenta and the extreme prematurity
Alan Flake, USA
A new paradigm for clinical research in obstetrics and neonatal medicine
Neena Modi, UK
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Friday, 5th April 2019
ALBERT ROOM
08.00 - 09.00 FREE COMMUNICATIONS 1
Chairpersons: Bernat Serra, Spain; Corinne Hubinont, Belgium
08.00 - 08.10 Internal iliac artery balloon occlusion: An approach to bleeding control during
cesarean hysterectomy for abnormal placentation
Swati Francis, India
08.10 - 08.20 Use of magnetic resonance imaging and ultrasound fusion imaging to improve
placenta accreta diagnosis
Sarah Guillon, France
08.20 - 08.30 Analysis of cesarean section for mid-trimester pregnancy termination in women
with placenta previa
Hiroaki Soyama, Japan
08.30 - 08.40 Method of bladder filling to prevent urinary system surgical trauma in manag-
ment of patients with placenta percreta
Victoria Barinova, Russia
08.40 - 08.50 Successful conservative surgical management of placenta percreta - a video
illustration
Joanna Sichitiu, Switzerland
08.50 - 09.00 Discussion
ST JAMES ROOM
08.00 - 09.00 FREE COMMUNICATIONS 2
Chairpersons: Bo Jacobsson, Sweden; Yariv Yogev, Israel
08.00 - 08.10 Labour probability estimation using a wearable pregnancy monitor: preliminary
validation
Julien Penders, USA
08.10 - 08.20 Predictive ability of uterine Doppler velocimetry in 1st trimester to detect growth
restriction
Mariana Rodríguez, Spain
08.20 - 08.30 Novel panel of midtrimester protein biomarkers predict preterm birth
Shaun Brennecke, Singapore
08.30 - 08.40 Comparison of sequential usage of mifepristone and double-balloon catheter
versus double-balloon catheter alone for induction of labour in term pregnancy
Oleg Baev, Russia
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08.40 - 08.50 Ureaplasma colonization does not increase inflammatory cytokines of amniotic
fluid in women without histologic chorioamnionitis
Jaehyun Park, South Korea
08.50 - 09.00 The presence of trophoblast spheroids alters toll-like receptor 5 activation in en-
dometrial cells in an in vitro model
Qijing Wang, UK
VICTORIA ROOM
08.00 - 09.00 FREE COMMUNICATIONS 3
Chairpersons: Despina Briana, Greece; Ranjan Pejaver, India
08.00 - 08.10 Maternal fetal infections and long-term neurodevelopmental outcomes in chil-
dren infected and uninfected at birth
Fiammetta Piersigilli, Italy
08.10 - 08.20 Features of the neonatal period of children with bronchial asthma
Anastasiia Saranchuk, Ukraine
08.20 - 08.30 The relation between capillary refilling time and kidney injury in asphyxiated pre-
term infants
Nushaba Panahova, Azerbaijan
08.30 - 08.40 A UK national survey on the current practice of using paracetamol to treat pa-
tent ductus arteriosus in preterm infants
Mona Noureldein, United Kingodm
08.40 - 08.50 Effect of oral zinc sulfate on hyperbilirubinemia of low birth weight neonates
Ashraf Mohammad Zadeh, Iran
08.50 - 09.00 Early respiratory support for meconium aspiration syndrome- is high flow nasal
cannula an answer?
Pavan Kalamdani, India
FLEMING ROOM
09.00 - 11.00 PLENARY SESSION 1: INTERVENTIONS WHICH MATTER
Chairpersons: Roberto Romero, USA; Neil Marlow, UK
09.00 - 09.30 Antibiotics to eradicate intra-amniotic infection/inflammation in patients with
cervical insufficiency, preterm labor and preterm PROM
Roberto Romero, USA
09.30 - 09.50 Prediction and prevention of preeclampsia
Liona Poon, Hong Kong
09.50 - 10.10 Prevention of preterm birth with progesterone
Eduardo Fonseca, Brazil
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10.10 - 10.30 Progesterone to prevent first trimester pregnancy loss
Arri Coomarasamy, UK
10.30 – 10.50 Operative vaginal delivery: the Odon device. Enhancing safety for mother and
baby
Tim Draycott, UK
10.50 – 11.00 Discussion
11.00 - 11.30 COFFE BREAK
FLEMING ROOM
11.30 - 13.00 CO-PLENARY SESSION 1: OBESITY AND ITS IMPACT ON MATERNAL INFANT HEALTH
Chairpersons: Gerard H. A. Visser, the Netherlands; Yariv Yogev, Israel
11.30 - 11.50 Obesity: impact on reproductive health and on maternal complications in preg-
nancy
Yariv Yogev, Israel
11.50 – 12.10 Maternal obesity and impact on long-term offspring health Gerard H.A. Visser, the Netherlands
12.10 – 12.30 Maternal obesity, when and how to prevent and treat
Angela Flynn, UK
12.30 – 12.50 The impact of neonatal weight gain on later obesity
Neena Modi, UK
12.50 - 13.00 Discussion
WHITTLE ROOM
11.30 - 13.00 CO-PLENARY SESSION 2: ENVIROMENTAL TOXICANTS AND REPRODUCTION
Chairpersons; Jeanne Conry, USA; Maria Dolores Gomez Roig, Spain
11.30 - 12.00 Environmental carcinogenesis and trasgenerational trasmission of carcinogenic
risk: from genetics to epigenetics
Ernesto Burgio, Italy
12.00 - 12.25 Environmental effects on male reproduction
Jorma Toppari, Finland
12.25 - 12.50 Prenatal exposures to endocrine disruptors and reproductive function in teen girls
Maria Dolores Gomez Roig, Spain
12.50 - 13.00 Discussion
13.00 – 14.30 BREAK
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WHITTLE ROOM
13.00 – 14.30 LUNCHEON SPONSORED SESSION*
EVOLVING EVIDENCE IN POST PARTUM HEMORRHAGE (PPH) PREVENTION
13.00 – 13.05 Introduction
Gian Carlo Di Renzo, Italy
13.05 ‒ 13.25 PPH epidemiology: a focus on the Philippines
Angela Aguilar, Philippines
13.25 ‒ 13.45 The Cochrane network meta-analysis of uterotonics: an update
Argyro Papadopoulou, UK
13.45 ‒ 14.00 The WHO recommendations on uterotonics for PPH prevention
Fernando Althabe, WHO - Switzerland
14.00 – 14.20 Maternal circulatory effects of oxytocics. The carbetocin myocardial trial
Leiv-Arne Rosseland, Norway
14.20 – 14.30 Discussion - Closing remarks
Gian Carlo Di Renzo, Italy
*Industry supported session
WHITTLE ROOM
14.30 – 16.30 PARALLEL SESSION 1: MATERNAL DISEASES
Chairpersons: Jacky Nizard, France; Catherine Nelson Piercy, UK
14.30 – 14.55 Renal disease Catherine Nelson-Piercy, UK
14.55 – 15.20 Epilepsy
Surabhi Nanda, UK
15.20 – 15.45 Heart disease
Jacky Nizard, France
15.45 – 16.10 Diabetes in pregnancy
Cynthia Gyamfi-Bannerman, USA
16.10 – 16.30 Discussion
FLEMING ROOM
14.30 – 16.30 PARALLEL SESSION 2: THE BRAIN OF THE FETUS AND THE NEWBORN
Chairpersons: Henrik Hagberg, Sweden; Pierre Gressens, France
14.30 - 14.55 Is exendin-4 a candidate for neuroprotection in the neonatal brain? Eridan Rocha-Ferreira, Sweden
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14.55 - 15.20 Preterm brain: MRI Manon Benders, the Netherlands
15.20 - 15.45 Cortical development during fetal and neonatal life Pierre Gressens, France
15.45 - 16.10 Neuroprotection in utero
Henrik Hagberg, Sweden-UK
16.10 - 16.30 Discussion
ALBERT ROOM
14.30 – 16.30 PARALLEL SESSION 3: THE TWINS
Chairpersons: Ruben Quintero, USA; Asma Khalil, UK
14.30 – 14.50 TTTS versus TAPS: similarities and differences
Ruben Quintero, USA
14.50 – 15.10 Stage 1 TTTS: Conservative management or Laser surgery?
Yves Ville, France
15.10 – 15.30 Challenges in counselling and management of selective fetal growth restriction
Ruben Quintero, USA
15.30 – 15.50 How to avoid stillbirth in twins?
Asma Khalil, UK
15.50 – 16.10 Outcomes of singleton pregnancies reduced from twins compared with ongoing
twin pregnancy
Pavel Calda, Czech Republic
16.10 – 16.30 Screening and prevention of preterm birth in twins
Roberto Romero, USA
ST JAMES ROOM
14.30 – 16.30 PARALLEL SESSION 4: ACCRETA PLACENTATION: FROM DIAGNOSIS TO
MANAGEMENT
Chairpersons: Eric Jauniaux, UK; Corinne Hubinont, Belgium
14.30 – 14.50 FIGO classification and the use of standardised research protocol
Eric Jauniaux, UK
14.50 - 15.10 Prenatal and perinatal clinical diagnosis
Sally Collins, UK
15.10 - 15.30 The role of peri-partum hysterectomy
Aris Antsaklis, Greece
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15.50 - 16.10 Risks and benefits of conservative management
José M. Palacios-Jarquemada, Argentina
16.10 - 16.30 Discussion and take home message
VICTORIA ROOM
14.30 – 16.30 SPECIAL SESSION 1: STEM CELLS IN PERINATAL MEDICINE
Chairpersons: Bernard Thebaud, Canada; Ariadne Malamitsi-Puchner, Greece
14.30 - 14.55 Stem cells for the neonatal brain
Pierre Gressens, France
14.55 - 15.20 Mesenchymal stromal cell-derived exosomes for neonatal lung injury
Stella Kourembanas, USA
15.20 – 15.45 Personalized perinatal medicine and the potential of stem cells therapy
Gennady Sukhikh, Russia
15.45 - 16.10 Regenerative medicine in neonatology: A new hope
Bernard Thébaud, Canada
16.10 - 16.30 Discussion
16.30 – 17.00 TEA BREAK
WHITTLE ROOM
17.00 – 18.30 PARALLEL SESSION 5: INDUCTION OF LABOR (IOL)
Chairpersons: Daniel Surbek, Switzerland; Kate Walker, UK
17.00 – 17.20 Where are we heading to in IOL?
Daniel Surbek, Switzerland
17.20 – 17.40 ARRIVE study: what it tells us
Dan Farine, Canada
17.40 – 18.00 Mechanical methods for IOL
Janesh Gupta, UK
18.00 – 18.20 Delivery at term: When how and why
Kate Walker, UK
18.20 – 18.30 Discussion
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FLEMING ROOM
17.00 - 18.30 PARALLEL SESSION 6: RESPIRATORY DISTRESS SYNDROME AND
BRONCHOPULMONARY DYSPLASIA
Chairpersons: Luc Zimmermann, the Netherlands, Suhas Kallapur, USA
17.00 - 17.20 Chorioamnionitis and BPD
Suhas Kallapur, USA
17.20 - 1740 CPAP failure
Luc Zimmermann, the Netherlands
17.40 - 18.00 BPD as a regenerative disease
Boris Kramer, the Netherlands
18.00 - 18.20 Vascular aspects in BPD
Irwin Reiss, the Netherlands
18.20 - 18.30 Discussion
VICTORIA ROOM
17.00 – 18.30 PARALLEL SESSION 7: RANDOMIZED CONTROLLED TRIALS IN PREGNANCY
ASSESSING MATERNAL INFANT MEDICINE
Chairpersons: Ben Mol, Australia; Zarko Alfirevic, UK
17.00 - 17.25 Misleading RCTs and effect on guidelines: recent examples
Dan Farine, Canada
17.25 – 17.50 STRIDER prospective IPD
Zarko Alfirevic, UK
17.50 - 18.15 The difference between a woman and an airplane
Ben Mol, Australia
18.15 - 18.30 Discussion
ALBERT ROOM
17.00 – 18.30 PARALLEL SESSION 8: HEALTH ECONOMICS IN MATERNAL-FETAL AND
NEONATAL MEDICINE
Chairpersons: Leila Adamyan, Russia; Gabriella Conti, UK
17.00 - 17.25 Economic stress and early programming of health and disease
Ariadne Malamitsi-Puchner, Greece
17.25 - 17.50 Cost effective innovations to improve newborn outcomes
Ranjan Kumar Pejaver, India
17.50 - 18.15 Medium and long-term effect of prenatal outcomes after economic stress
Gabriella Conti, UK
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18.15 - 18.30 Discussion
ST JAMES ROOM
17.00 – 18.30 SPECIAL SESSION 2: THE ORIGINS OF NEURODEVELOPMENTAL DISEASE: FROM
CONCEPTION TO CHILDHOOD
Chairpersons: Despina Briana, Greece; Nicola Robertson, UK
17.00 - 17.20 Neurodevelopmental consequences of fetal and neonatal adaption to a
hypoxic environment.
Irwin K M Reiss, the Netherlands
17.20 - 17.40 Improving outcomes for preterm babies – the bigger picture.
Jan G. Nijhuis, the Netherlands
17.40 - 18.00 The intrauterine determinants of autism spectrum disorders
Despina Briana, Greece
18.00 - 18.20 Term NE – how can we augment protection from therapeutic hypothermia?
Nicola Robertson, UK
18.20 - 18.30 Discussion
WHITTLE ROOM
18.30 – 19.00 HAPPY HOUR LECTURE
The metabolic ghetto
Jonathan Wells, UK
Saturday, 6th April 2019
ALBERT ROOM
08.00 - 09.00 FREE COMMUNICATIONS 4
Chairpersons: Graziano Clerici, Italy; Dan Farine, Canada
08.00 - 08.10 Association between perinatal death and bile acid levels in intrahepatic choles-
tasis of pregnancy: a systematic review
Daniele Di Mascio, Italy
08.10 - 08.20 Nov association between intrahepatic cholestasis of pregnancy and gestational
diabetes mellitus
Agata Majewska, Poland
08.30 - 08.40 The significance of hereditary thrombophilia in the reproductive dysfunction of
women from the Republic of Moldova
Diana Mitriuc, Moldova
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08.20 - 08.30 The association between exposure to non-steroidal anti-inflammatory drugs dur-
ing pregnancy and risk of subsequent miscarriage: a systematic review
Joanna Brecher, UK
08.40 - 08.50 Maternal smoking in pregnancy, fetal behavior and newborn state: An observa-
tional ultrasound study
Geidy Nolasco, USA
08.50 - 09.00 Interactive Medical Intelligence utilization to achieve optimal outcome for neo-
nate and mother
Gerard Pregenzer, USA
ST JAMES ROOM
08.00 - 09.00 FREE COMMUNICATIONS 5
Chairpersons: Irene Giardina, Italy; Aala Ebraishy, Egypt
08.00 - 08.10 Plasma lipids identify gestational diabetes mellitus in early pregnant stage
Ya Gao, China
08.10 - 08.20 Does the location of the placenta influence the degree of blood loss and histo-
pathological confirmation during the triple-P procedure?
Silvia Espuelas Malón, Spain
08.20 - 08.30 The Introduction of 3D/4D Based Spatio – Temporal Image Correlation (STIC) dur-
ing routine fetal anomaly scan improves rate of completion of fetal cardiac ex-
amination and decreases referral for fetal echocardiogram.
Ahmed Badreldeen, Quatar
08.30 - 08.40 First trimester ultrasound features associated with subsequent miscarriage: A pro-
spective study
Tracey Taylor, Australia
08.40 - 08.50 High multiplex digital PCR for NIPT and cancer mutation detection
Youxiang Wang, USA
08.50 - 09.00 Discussion
VICTORIA ROOM
08.00 - 09.00 FREE COMMUNICATIONS 6
Chairpersons: Ola D. Saugstad, Norway; Pierre Gressens, France
08.00 - 08.10 The effectiveness of surfactant replacement therapy in late preterm neonates
with severe respiratory disorders. A retrospective cohort comparative study
Oleg Ionov, Russia
20
08.10 - 08.20 Using umbilical cord blood for NICU admission laboratory tests: current practice
and literature review
Veronica Samedi, Canada
08.20 - 08.30 A clinical scoring system to predict the need for extensive resuscitation at birth in
very low birth weight infants
Juyoung Lee, South Korea
08.30 - 08.40 The early immunological diagnostics of neonatal sepsis with respiratory pathology
Marina Pukhtinskaya, Russia
08.40 - 08.50 The effect of parenteral nutrition arginine supplementation on early immune sys-
tem development in very preterm infants
Laura Burgess, UK
08.50 - 09.00 How is arginine intake from parenteral nutrition reflected in plasma arginine levels
of the preterm neonatal population ? a systematic review
Chandini Menon Premakumar, UK
WESLEY ROOM
08.00 - 09.00 FREE COMMUNICATIONS 7
Chairpersons: Manon Benders, the Netherlands; Sabita Uthaya, UK
08.00 - 08.10 Identification of parental needs in a neonatal intensive care unit: a first step in
the development of the NeoParent mobile application
Inge Tency, Belgium
08.10 - 08.20 Longitudinal changes of urinary biomarkers in late preterm infants during early
neonatal period
Sook-Hyun Park, South Korea
08.20 - 08.30 Postnatal determinants of blood pressure at 6.5 years of age in children born ex-
tremely preterm
Itay Zamir, Sweden
08.30 - 08.40 Feasibility of umbilical cord blood collection in neonates at high risk of brain
damage
Angela Segler, Germany
08.40 - 08.50 Neonatal neuroprotective effect of lactoferrin in a rat model of prenatal
hypoxia
Vadim Vasilyev, Russia
08.50 - 09.00 Discussion
21
FLEMING ROOM 09.00 - 11.00 PLENARY SESSION 2: THE CHALLENGE OF IUGR FETUS AND NEWBORN
Chairpersons: Gerard H.A. Visser, the Netherlands; Jason Gardosi, UK
09.00 - 09.20 Is the threshold for viability depending on fetal size?
Neil Marlow, UK
09.20 - 09.40 Management of early fetal growth restriction
Christoph Lees, UK
09.40 - 10.00 Early delivery of fetal growth restriction; are antenatal steroids useful?
Umberto Simeoni, Switzerland
10.00 - 10.20 Improving antenatal detection of fetal growth restriction:victories and challenges
Jason Gardosi, UK
10.20 - 10.40 Management of late fetal growth restriction; many unsolved issues
Gerard H. A. Visser, the Netherlands
10.40 - 11.00 Long term follow-up of fetal growth restriction
Fatima Crispi, Spain
11.00 - 11.30 COFFE BREAK
FLEMING ROOM
11.30 - 13.00 CO-PLENARY SESSION 3: NUTRITION AND EARLY FEEDING IN PERINATAL PERIOD
Chairpersons: Umberto Simeoni, Switzerland; Neena Modi, UK
11.30 - 11.50 The evidence base for current recommendations for feeding extremely preterm
neonates Cheryl Battersby, UK
11.50 - 12.10 Current recommendations for parenteral nutrition of extremely preterm neonates
Sabita Uthaya, UK
12.10 - 12.30 Biomarkers to guide neonatal nutrition research Umberto Simeoni, Switzerland
12.30 - 12.50 Improving neonatal nutrition: how to resolve urgent uncertainties Neena Modi, UK
12.50 - 13.00 Discussion
22
WHITTLE ROOM
11.30 - 13.00 CO-PLENARY SESSION 4: PREVENTION IS BETTER THAN CARE: THE RH DISEASE
PARADIGMA
Chairpersons: Gerard H.A. Visser, the Netherlands; Gian Carlo Di Renzo, Italy
11.30 - 11.45 Introduction of Rh disease: 50 years of Rh eradication
Gian Carlo Di Renzo, Italy
11.45 - 12.00 Prevention of Rh disease: global figures
Eduardo Fonseca, Brazil
12.00 - 12.20 Fetal Rh isoimmunization: what to do?
Gennady Sukhikh, Russia
12.20 - 12.35 Neonatal Rh disease: still a burden
Marcela Contreras, UK
12.35 – 12.50 The forthcoming 50 years: global strategies
Gerard H. A. Visser, the Netherlands
12.50 - 13.00 Discussion
VICTORIA ROOM
11.30 - 16.30 SPECIAL SESSION 3 - FETAL THERAPY - 1st PART
Chairpersons: Ruben Quintero, USA; Ramen Chmait, USA
11.30 - 12.00 CCAM/CPAM and other fetal lung lesions
Eftichia Kontopoulos, USA
12.00 - 12.30 Percutaneous fetoscopic treatment of myelomeningocele: The US Fetus trial
Ramen Chmait, USA
13.00 – 14.30 BREAK
VICTORIA ROOM
11.30 - 16.30 SPECIAL SESSION 3 - FETAL THERAPY - 2nd PART
Chairpersons: Ruben Quintero, USA; Ramen Chmait, USA
12.30 - 13.00 Management of fetal lower urinary tract obstruction (LUTO).
Ruben Quintero, USA
14.30 – 15.00 Discordant anomalous monochorionic twins
Eftichia Kontopoulos, USA
15.00 – 15.30 Assessment and management of selective intrauterine growth restriction (SIUGR)
Ramen Chmait, USA
23
15.30 – 16.00 Laser therapy for twin-twin transfusion syndrome. challenging cases
Ruben Quintero, USA
16.00 – 16.30 Discussion
FLEMING ROOM
14.30 - 16.30 PARALLEL SESSION 9: NEW TRENDS IN NEONATOLOGY
Chairpersons: Christian P. Speer, Germany; Stella Kourembanas, USA
14.30 - 14.55 The first golden minutes: The role of sustained inflation and late cord clamping
Haresh Kirpalani, USA
14.55 – 15.20 Work of breathing and thoracoabdominal asynchrony
Anne Greenough, UK
15.20 - 15.45 Mesenchymal stem cells: Magic cure for cerebral injury of preterm infants?
Won-Soon Park, South Korea
15.45 - 16.10 Visualization of pain perception of preterm infants
Rebeccah Slater, UK
16.10 - 16.30 Discussion
WHITTLE ROOM
14.30 - 16.30 PARALLEL SESSION 10: CESAREAN DELIVERY
Chairpersons: Mike Robson, Ireland; Vincenzo Berghella, USA
14.30 – 14.50 Caesarean section - classification and indications
Mike Robson, Ireland
14.50 – 15.10 Cesarean technique part 1: intraoperative preparation, and from skin to baby
Vincenzo Berghella, USA
15.10 - 15.30 Cesarean technique part 2: From baby to skin closure and more
A. Dhanya Mackeen, USA
15.30 – 15.50 Accreta management
Huixia Yang, China
15.50 – 16.10 Cesarean section in twins
Victor Radzinsky, Russia
16.10 – 16.30 The care for the bleeding obstetric patient addressing inequality in resources and
training
Offer Erez, Israel
24
ST JAMES ROOM
14.30 - 16.30 PARALLEL SESSION 11: PRENATAL DIAGNOSIS: WHAT IS NEW?
Chairpersons: Gordon Smith, UK; Giuseppe Rizzo, Italy
14.30 - 14.55 Update on the use of invasive technique in prenatal diagnosis
Tullio Ghi, Italy
14.55 - 15.20 Whole exome sequencing in prenatal diagnosis
Mark Kilby, UK
15.20 - 15.45 NIPT, where next?
Maria del Mar Gil Mira, Spain
15.45 - 16.10 Abnormalities missed because of NIPT
Mark Evans, USA
16.10 - 16.30 Classification and management of fetal lower urinary tract obstruction
Katia Bilardo, the Netherlands
ALBERT ROOM
14.30 - 16.30 SPECIAL SESSION 4: HOT NEONATAL TOPICS
Chairpersons: Josef Neu, USA; Eduardo Bancalari, USA
14.30 - 14.55 Antenatal steroids: benefits, risk and new treatment strategies
Alan Jobe, USA
14.55 - 15.20 Oxygen in the premature: a difficult balance
Eduardo Bancalari, USA
15.20 - 15.45 Sustained Inflation in the delivery room: results of the SAIL trial
Haresh Kirpalani, Canada
15.45 - 16.10 Donor human milk: Is it a panacea?
Josef Neu, USA
16.10 - 16.30 Discussion
16.30 – 17.00 TEA BREAK
FLEMING ROOM
17.00 - 18.30 PARALLEL SESSION 12: NEW ISSUES ON PRETERM BIRTH AND PREMATURITY
Chairpersons: Sonia Hassan, USA; David Sweet, UK
17.00 - 17.20 Biomarkers for preterm birth prediction
Gian Carlo Di Renzo, Italy
17.20 - 17.40 Fetal monitoring: dilemmas and practice recommendations
Edwin Chandraharan, UK
25
17.40 - 18.00 Omega 3 in the prevention: there is evidence?
Zarko Alfirevic, UK
18.00 - 18.20 Delayed cord clamping
William Tarnow Mordi, Australia
18.20 - 18.30 Discussion
WHITTLE ROOM
17.00 – 18.00 PARALLEL SESSION 13: NEONATAL OUTCOME: WHICH MATTERS?
Chairpersons: Luc Zimmermann, the Netherlands; Irina Soldatova, Russia
17.00 – 17.25 The role of perinatal centers in reducing infant mortalities in Russia
Irina Soldatova, Russia
17.25 – 17.50 Euro-Peristat data: what have we learned?
Jan Nijhuis, the Netherlands
17.50 - 18.00 Discussion
ST JAMES ROOM
17.00 - 18.30 SPECIAL SESSION 5 – MATERNAL HEMODINAMICS: BEYOND BLOOD PRESSURE
SCREENING IN PREGNANCY
Chairpersons: Enrico Ferrazzi, Italy; Christopher Lees, UK
17.00 - 17.15 Heart, arterial and the venous compartment changes in pregnancy
Wilfried Gyselaers, Belgium
17.15 - 17.30 Pre-pregnancy and pregnancy hemodynamic in hypertensive disorders
of pregnancy
Christopher Lees, UK
17.30 - 17.45 Maternal hemodynamics and HDP in pregnancy and postpartum - molecular
markers and placental correlates
Enrico Ferrazzi, Italy
17.45 - 18.00 Maternal hemodynamics in severe IUGR
Herbert Valensise, Italy
18.00 - 18.15 Fetal growth in chronic hypertension and preeclampsia
Tullio Ghi, Italy
18.15 - 18.30 Tailored antihypertensive therapy
Marc Spaanderman, the Netherlands
26
WHITTLE ROOM
18.30 – 19.00 HAPPY HOUR LECTURE
How much is medicine, how much is social developments in getting better?
Gerard H.A. Visser, the Netherlands
WHITTLE ROOM
19.00 CLOSING
27
ATELIERS:
5th April 2019
09.00 - 11.00 A1: MUSIC AND MUSICOTHERAPY IN PERINATAL PERIOD
Birgit Arabin, Germany; Enrico Granieri, Italy
11.30 - 13.00 A2: SMALL PROBLEMS IN THE NEONATAL UNIT AND NICU
Nadja Haiden, Austria
11.30 - 13.00 A3: PHYTOTHERAPY
James S. Mclay, UK
14.30 – 16.00 A4: SMALL PROBLEMS IN PREGNANCY AND LABOUR
Yariv Yogev, Israel; Enrico Ferrazzi, Italy
6th April 2019
09.00 – 10.30 A5: HOW TO WRITE A GOOD SCIENTIFIC PAPER
Janesh K. Gupta, UK
11.30 – 13.00 A6: HOW TO COLLABORATE AND COMMUNICATE WITH PARENTS
IN CRITICAL DECISION MAKING SITUATIONS
Silke Mader, Germany
Multidisciplinary antenatal and perinatal palliative care
Fauzia Paize, UK
How can we healthcare professionals make the parents journey
bearable in the neonatal period?
Roisin Mckeon-Carter, UK
How parents can be involved in making critical care decisions:
a parents perspective
Silke Mader, Germany
14.30 - 16.30 A7: PAIN IN THE NICU
Ricardo Carbajal, Portugal; Marsha Campbell-Yeo, Canada
17.00 - 18.30 A8: NON INVASIVE RESPIRATORY SUPPORT TO THE NEWBORN
Peter Davis, Australia; Haresh Kirpalani, Canada
17.00 - 18.00 A9: EXERCISE IN PREGNANCY
Vincenzo Berghella, USA