2 world congress on maternal fetal ......1 2nd world congress on maternal fetal neonatal medicine...

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2nd WORLD CONGRESS ON MATERNAL FETAL NEONATAL MEDICINE

SCIENTIFIC PROGRAMME

Thursday, 4th April 2019

PRE-CONGRESS POSTGRADUATE COURSES

FLEMING ROOM

09.00 – 16.30 COURSE 1: THE FIRST TRIMESTER PRENATAL TESTING

Course Directors: Kypros Nicolaides, UK; Katia Bilardo, the Netherlands;

Liona Poon, Hong Kong

ANEUPLOIDIES:

09.00 - 09.30 Universal cfDNA testing by targeted approach

Jacques Jani, Belgium

09.30 - 10.00 Universal cfDNA testing by genome wide approach

Mireille Bekker, the Netherlands

10.00 - 10.30 Abnormalities missed because of NIPT

Mark Evans, USA

10:30 - 11.00 Contingent cfDNA testing

Kypros Nicolaides, UK

11.00 – 11.10 Discussion

11.10 - 11.30 BREAK

STRUCTURAL ANOMALIES:

11.30 - 12.00 The first trimester anomaly scan

Katia Bilardo, the Netherlands

12.00 - 12.30 The first trimester fetal echo

Vita Zidere, UK

12.30 - 13.10 LUNCH BREAK

PREECLAMPSIA:

13:10 - 13:40 How best should we screen for pre-eclampsia?


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GROWTH ABNORMALITIES/STILLBIRTH:

13.40 - 14.10 Do we have the right tools to detect growth abnormalities and stillbirth?

Ranjt Akolekar, UK

PRETERM BIRTH:

14.10 - 14.40 New advances for early prediction of preterm birth

Eduardo Fonseca, Brazil

TWINS:

14.40 - 15.10 How to avoid complications in twins?

Asma Khalil, UK

CLOSING:

15.10 - 15.40 Inverting the pyramid: where are we heading?

Kypros Nicolaides, UK

15.40 - 16.00 Discussion and end of the course

WHITTLE ROOM

09.00 – 13.20 COURSE 2: PRETERM NEWBORN RESUSCITATION

Course Directors: Eduardo Bancalari, USA; Ola D. Saugstad, Norway;

Christian Poets, Germany

09.00 - 09.20 Surfactant delivery: When, how?

David Sweet, UK

09.20 - 09.40 Current recommendations on the use of oxygen in the delivery room

Ola D. Saugstad, Norway

09.40 - 10.00 Are we using the best tools for respiratory support in the delivery room?

Eduardo Bancalari, USA

10.00 - 10.20 Strategies to protect the immature brain after birth

Pierre Gressens, France

10.20 - 10.40 Discussion

10.40 - 11.10 BREAK

11.10 - 11.30 Perinatal infection and neonatal adaptation

Alan Jobe, USA

11.30 - 11.50 Bonding the preterm infant in the delivery room

Christian Poets, Germany

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12.00 - 12.20 Timing of cord clamping, does it make a difference?

Haresh Kirpalani, Canada

12.20 - 12.40 Interventions to avoid early neonatal hypoglycemia

Umberto Simeoni, Switzerland

12.40 - 13.00 Initial respiratory support in the delivery room

Peter Davis, Australia


GUILD ROOM

09.00 - 12.30 COURSE 3: GENETICS, EPIGENETICS AND THE DEVELOPMENTAL ORIGINS OF ADULT

HEALTH (in cooperation with DOhAD International Society)

Course Directors: Lucilla Poston, UK, Mark Hanson, UK

09.00 - 09.20 Introduction: DOHaD and maternal fetal medicine

Lucilla Poston, UK

09.20 - 09.50 Methods in epigenetics research

Lucia Migliore, Italy

09.50 - 10.10 Multidisciplinary approach and DOHaD perspective on kidney size and function

evaluation in the perinatal period

Benito Cappuccini, Italy


10.20 - 10.40 BREAK

10.40 - 11.10 Maternal emotional health and offspring neurodevelopment

Yap Seng Chong, Singapore

11.10 - 11.40 Epigenetics and environmental toxicants in development

Paolo Vineis, UK

11.40 - 12.00 Paternal epigenetic effects on development

Adam Watkins, UK


12.30 – 13.00 Conclusion: DOHaD and global health

Lucilla Poston, UK

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WHITTLE ROOM

13.40 – 17.00 COURSE 4: INFECTIONS IN THE PRENATAL AND NEONATAL PERIOD

Course Directors: Alan Jobe, USA; Paolo Manzoni, Italy;

Laurent Mandelbrot, France

13.40 – 14.00 Epidemiology and microbiology of Vertical sepsis in neonates in the era of

universal IAP for GBS

Ranjan Pejaver, India

14.00 – 14.20 Neonatal sepsis and possible approaches involving use of stem cells:

state of the art

Bernard Thebaud, Canada

14.20 – 14.40 Neonatal infections and water delivery: state of the art

Stefano Uccella, Italy

14.40 – 15.00 Perinatal fungal infections in the NICU

Omer Erdeve, Turkey

15.00 – 15.20 Intrapartum antibiotics and neonatal microbioma: which implication?

Josef Neu, USA

15.20 – 15.40 Update on perinatal CMV prevention and management

Giovanni Nigro, Italy

15.40 – 16.00 Transitioning from fetal to neonatal immune status: which are the main clinical

implications?

Jim Wynn, USA

16.00 – 16.20 Clinical and animal models of chorioamnionitis: latest updates

Suhas Kallapur, USA


WESLEY ROOM

09.00 – 16.30 COURSE 5: SAFE MOTHERHOOD AND NEWBORN HEALTH

(JOINTLY ORGANISED WITH FIGO)

Course Directors: Maria Fernanda Escobar, Colombia;

Gerard H. A. Visser, the Netherlands; Diogo Ayres-Do-Campos, Portugal

09.00 - 09.10 Opening

Gerard H. A. Visser, the Netherlands

SESSION 1: OBSTETRIC EMERGENCIES

Chair: Maria Fernanda Escobar, Colombia

09.10 - 09-30 Prevention of PPH: new evidence

Daniel Surbek, Switzerland

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09.30 - 09.50 Update in the treatment of PPH

Anton Mikhailov, Russia

09.50 - 10.30 Diagnosis and management of maternal sepsis

Maria Fernanda Escobar, Colombia


11.00 - 11.30 BREAK

SESSION 2: OBSTETRICS IN LOW-RESOURCE COUNTRIES

Chair: William Stones, Malawi

11.30 - 11.50 Reintroduction of vaginal instrumental deliveries,

Jan Van Roosmalen, the Netherlands

11.50 - 12.10 Fetal monitoring in low-resource countries

Jan Van Roosmalen, the Netherlands

12.10 - 12.30 Affordable and low-maintenance obstetric devices

Diogo Ayres-de-Campos, Portugal



SESSION 3: TOO MANY, TOO RISKY?

Chair: Gerard H. A. Visser, the Netherlands; Diogo Ayres-de-Campos, Portugal

14.00 - 14.30 Excessive use of C-sections


14.30 - 14.50 Excessive number of vaginal examinations during labour?

Diogo Ayres-de-Campos, Portugal

14.50 - 15.10 How long can we allow the second stage of labour to last?

Dan Farine, Canada

15.10 - 15.30 Role of fetal-maternal Doppler velocimetry at term

Irene Giardina, Italy

15.30 - 15.50 Excessive use of episiotomies

Anwar Nassar, Lebanon


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16.10 - 16.40 FIGO minimal staffing recommendations for maternity hospitals

William Stones, Malawi


ST JAMES ROOM

09.00 – 15.30 COURSE 6: PLACENTA ACRRETA SPECTRUM DISORDERS (PAS): MAKING DECISIONS

Course Directors: Josè M. Palacios Jaraquemada, Argentina;

Corinne Hubinont, Belgium; Mohamed Momtaz, Egypt

09.00 - 09.10 Introduction

José M. Palacios-Jaraquemada, Argentina

09.10 - 09.30 Is it really possible to reduce the incidence of PAS?


09.3 0- 09.50 Emergency versus elective management for PAS

Mohamed Momtaz, Egypt

09.50 - 10.10 Iliac internal vascular control complications


10.10 - 10.20 BREAK

10.20-10.40 Management protocol in severe postpartum hemorrhage


10.40 - 11.00 Standardized surgical technique of hysterectomy for PAS


11.00 - 11.20 Why some PAS locations are associated with high morbidity and mortality?


11.20 - 12.00 Discussion and home messages



13.00 - 13.20 How different is a premature newborn at 34 or 36/7 weeks?

Ola D. Saugstad, Norway

13.20 - 13.40 Management of PAS: Expectant or immediate treatment

Corinne Hubinont, Belgium

13.40 - 14.00 PAS in low resources settings: What can we do?


14.00 - 14.20 PAS diagnosis: Are we using the same signs?

Eric Jauniaux, UK

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14.20 - 14.40 Timing of caesarean section according to urgency. Rupture, massive bleeding

Aris Antsaklis, Greece

14.40 - 15.00 News in etiopathology could change our concept of prophylactic uterine

repair?

Eric Jauniaux, UK

15.00 - 15.30 Discussion and home messages


VICTORIA ROOM

09.00 – 16.30 COURSE 7: PRETERM BIRTH: PREVENTION AND PREDICTION

A PREIS SCHOOL ACADEMY COURSE

Course Directors: Eduardo Fonseca, Brazil; Bo Jacobsson, Sweden

09.00 – 09.10 General introduction

Course Directors

09.10 – 9.30 Historical and clinical risk factors (history of preterm birth, body mass index,

life style, interpregnancy interval)

Bo Jacobsson, Sweden

09.30 – 09.50 The genetics of preterm birth

Joe Leigh Simpson, USA

09.50 – 10.10 Cervical ultrasound as a screening method for preterm birth


10.10 - 10.30 New imaging modalities for cervical length for the prediction of preterm birth

Sonia Hassan, USA

10.30 - 10.50 Biomarkers of preterm delivery in first and second trimester in asymptomatic

women: an update

Andrew Shennan, UK


11.00 – 11.20 BREAK

11.20 – 11.50 Genetics of gestational age and preterm delivery: an update

Luis J. Muglia, USA

11.50 – 12.20 Prediction of preterm birth in the first trimester



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12.30 – 13.30 LUNCH BREAK

13.30 – 14.00 Vaginal progesterone for the prevention of preterm birth

Roberto Romero, USA

14.00 – 14.20 Aspirin to all or to selected population

Marion A. de Boer, the Netherlands

14.20 – 14.40 Cerclage for the prevention of preterm birth

Vincenzo Berghella, USA

14.40 – 15.00 Pessary for the prevention of preterm birth

Maria M. Goya Canino, Spain

15.00 – 15.40 Corticosteroides 34 to 36 and rescue doses

Pro: Cynthia Gyamfi Bannermann, USA Con: Gerard H.A. Visser, the Netherlands

15.40 – 16.10 Special Lecture: Preterm labour as syndrome

Roberto Romero, USA

16.10 – 16.30 Discussion and closing remarks

GUILD ROOM

13.30 - 16.30 COURSE 8: TIPS AND TRICKS IN ULTRASOUND AND DOPPLER SCAN IN

PREGNANCY: LIVE SCAN

Course Directors: Graziano Clerici, Italy; Giuseppe Rizzo, Italy

13.30 - 13.35 Introduction to the course

Giuseppe Rizzo, Italy

13.35 - 14.15 Anomaly scan: tips and tricks

Graziano Clerici, Italy

14.15 - 14.45 Fetal anomaly scan: interactive live scan



15.00 - 15.30 BREAK

15.30 - 16.00 Maternal-fetal hemodynamics: tips and tricks

Giuseppe Rizzo, Italy

16.00 - 16.30 Maternal-fetal hemodynamics: interactive live scan



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ALBERT ROOM

09.00 - 16.00 COURSE 9 – CRITICALLY ILL OBSTETRICS PATIENTS

Course Director: Daniela Vazquez, Argentina

09.00 – 09.20 Introduction

Daniela Vasquez, Argentina

HYPERTENSIVE DISORDERS

09.20 – 09.50 Definitions and recognition of severity of illness. Presentation of severe forms

of hypertensive disease of pregnancy

Liliana Voto, Argentina

09.50 – 10.10 Initial management of severe preeclampsia to prevent maternal morbidity

and mortality

Luca Marozio, Italy

10.10 – 10.30 Indications for delivery in women with hypertensive disease of pregnancy

Rasha Ahmed Mostafa Kamel, Egypt

10.30 – 10.45 Case presentation


10.45 – 11.00 Discussion & take home message


11.00 – 11.20 BREAK

POSTPARTUM HEMORRHAGE

11.20 – 11.40 Severe postpartum hemorrhage: diagnosis, quantification, and detection of

occult shock


11.40 – 12.00 DIC and pregnancy challenges in diagnosis and treatment

Offer Erez, Israel

12.00 – 12.20 Medical management of severe postpartum hemorrhage

Rasha Ahmed Mostafa Kamel, Egypt

12.20 – 12.40 Surgical management of postpartum hemorrhage

José M. Palacios Jaraquemada, Argentina

12.40 – 13.00 Case presentation, discussion and take home message

José M. Palacios Jaraquemada, Argentina

13.00 – 13.40 LUNCH BREAK

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PUERPERAL SEPSIS

13.40 – 14.00 Diagnosis, classification and causes of puerperal sepsis


14.00 – 14.20 Initial treatment of sepsis: the importance of considering the golden hour.


14.20 – 14.40 Puerperal sepsis: source control and indications for hysterectomy


14.40 – 15.00 Case presentation & take home message


PULMONARY EMBOLISM

15.00 – 15.20 Detection and urgent treatment of pulmonary embolism

Jacky Nizard, France

15.20 – 15.40 What has changed the need for DVT and pulmonary embolism prophylaxis?

Dan Farine, Canada

15.40 – 16.00 Case presentation & take home message


16.00 - 16.15 Conclusions


WHITTLE ROOM

18.00 – 19.30 OPENING & WELCOME RECEPTION

OPENING REMARKS

The Organisers

KEY NOTE ADDRESSES

The artificial placenta and the extreme prematurity

Alan Flake, USA

A new paradigm for clinical research in obstetrics and neonatal medicine

Neena Modi, UK

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Friday, 5th April 2019

ALBERT ROOM

08.00 - 09.00 FREE COMMUNICATIONS 1

Chairpersons: Bernat Serra, Spain; Corinne Hubinont, Belgium

08.00 - 08.10 Internal iliac artery balloon occlusion: An approach to bleeding control during

cesarean hysterectomy for abnormal placentation

Swati Francis, India

08.10 - 08.20 Use of magnetic resonance imaging and ultrasound fusion imaging to improve

placenta accreta diagnosis

Sarah Guillon, France

08.20 - 08.30 Analysis of cesarean section for mid-trimester pregnancy termination in women

with placenta previa

Hiroaki Soyama, Japan

08.30 - 08.40 Method of bladder filling to prevent urinary system surgical trauma in manag-

ment of patients with placenta percreta

Victoria Barinova, Russia

08.40 - 08.50 Successful conservative surgical management of placenta percreta - a video

illustration

Joanna Sichitiu, Switzerland


ST JAMES ROOM


Chairpersons: Bo Jacobsson, Sweden; Yariv Yogev, Israel

08.00 - 08.10 Labour probability estimation using a wearable pregnancy monitor: preliminary

validation

Julien Penders, USA

08.10 - 08.20 Predictive ability of uterine Doppler velocimetry in 1st trimester to detect growth

restriction

Mariana Rodríguez, Spain

08.20 - 08.30 Novel panel of midtrimester protein biomarkers predict preterm birth

Shaun Brennecke, Singapore

08.30 - 08.40 Comparison of sequential usage of mifepristone and double-balloon catheter

versus double-balloon catheter alone for induction of labour in term pregnancy

Oleg Baev, Russia

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08.40 - 08.50 Ureaplasma colonization does not increase inflammatory cytokines of amniotic

fluid in women without histologic chorioamnionitis

Jaehyun Park, South Korea

08.50 - 09.00 The presence of trophoblast spheroids alters toll-like receptor 5 activation in en-

dometrial cells in an in vitro model

Qijing Wang, UK

VICTORIA ROOM


Chairpersons: Despina Briana, Greece; Ranjan Pejaver, India

08.00 - 08.10 Maternal fetal infections and long-term neurodevelopmental outcomes in chil-

dren infected and uninfected at birth

Fiammetta Piersigilli, Italy

08.10 - 08.20 Features of the neonatal period of children with bronchial asthma

Anastasiia Saranchuk, Ukraine

08.20 - 08.30 The relation between capillary refilling time and kidney injury in asphyxiated pre-

term infants

Nushaba Panahova, Azerbaijan

08.30 - 08.40 A UK national survey on the current practice of using paracetamol to treat pa-

tent ductus arteriosus in preterm infants

Mona Noureldein, United Kingodm

08.40 - 08.50 Effect of oral zinc sulfate on hyperbilirubinemia of low birth weight neonates

Ashraf Mohammad Zadeh, Iran

08.50 - 09.00 Early respiratory support for meconium aspiration syndrome- is high flow nasal

cannula an answer?

Pavan Kalamdani, India

FLEMING ROOM

09.00 - 11.00 PLENARY SESSION 1: INTERVENTIONS WHICH MATTER

Chairpersons: Roberto Romero, USA; Neil Marlow, UK

09.00 - 09.30 Antibiotics to eradicate intra-amniotic infection/inflammation in patients with

cervical insufficiency, preterm labor and preterm PROM

Roberto Romero, USA

09.30 - 09.50 Prediction and prevention of preeclampsia


09.50 - 10.10 Prevention of preterm birth with progesterone


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10.10 - 10.30 Progesterone to prevent first trimester pregnancy loss

Arri Coomarasamy, UK

10.30 – 10.50 Operative vaginal delivery: the Odon device. Enhancing safety for mother and

baby

Tim Draycott, UK


11.00 - 11.30 COFFE BREAK

FLEMING ROOM

11.30 - 13.00 CO-PLENARY SESSION 1: OBESITY AND ITS IMPACT ON MATERNAL INFANT HEALTH

Chairpersons: Gerard H. A. Visser, the Netherlands; Yariv Yogev, Israel

11.30 - 11.50 Obesity: impact on reproductive health and on maternal complications in preg-

nancy

Yariv Yogev, Israel

11.50 – 12.10 Maternal obesity and impact on long-term offspring health Gerard H.A. Visser, the Netherlands

12.10 – 12.30 Maternal obesity, when and how to prevent and treat

Angela Flynn, UK

12.30 – 12.50 The impact of neonatal weight gain on later obesity

Neena Modi, UK


WHITTLE ROOM

11.30 - 13.00 CO-PLENARY SESSION 2: ENVIROMENTAL TOXICANTS AND REPRODUCTION

Chairpersons; Jeanne Conry, USA; Maria Dolores Gomez Roig, Spain

11.30 - 12.00 Environmental carcinogenesis and trasgenerational trasmission of carcinogenic

risk: from genetics to epigenetics

Ernesto Burgio, Italy

12.00 - 12.25 Environmental effects on male reproduction

Jorma Toppari, Finland

12.25 - 12.50 Prenatal exposures to endocrine disruptors and reproductive function in teen girls

Maria Dolores Gomez Roig, Spain


13.00 – 14.30 BREAK

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WHITTLE ROOM

13.00 – 14.30 LUNCHEON SPONSORED SESSION*

EVOLVING EVIDENCE IN POST PARTUM HEMORRHAGE (PPH) PREVENTION

13.00 – 13.05 Introduction

Gian Carlo Di Renzo, Italy

13.05 ‒ 13.25 PPH epidemiology: a focus on the Philippines

Angela Aguilar, Philippines

13.25 ‒ 13.45 The Cochrane network meta-analysis of uterotonics: an update

Argyro Papadopoulou, UK

13.45 ‒ 14.00 The WHO recommendations on uterotonics for PPH prevention

Fernando Althabe, WHO - Switzerland

14.00 – 14.20 Maternal circulatory effects of oxytocics. The carbetocin myocardial trial

Leiv-Arne Rosseland, Norway

14.20 – 14.30 Discussion - Closing remarks


*Industry supported session

WHITTLE ROOM

14.30 – 16.30 PARALLEL SESSION 1: MATERNAL DISEASES

Chairpersons: Jacky Nizard, France; Catherine Nelson Piercy, UK

14.30 – 14.55 Renal disease Catherine Nelson-Piercy, UK

14.55 – 15.20 Epilepsy

Surabhi Nanda, UK

15.20 – 15.45 Heart disease


15.45 – 16.10 Diabetes in pregnancy

Cynthia Gyamfi-Bannerman, USA


FLEMING ROOM

14.30 – 16.30 PARALLEL SESSION 2: THE BRAIN OF THE FETUS AND THE NEWBORN

Chairpersons: Henrik Hagberg, Sweden; Pierre Gressens, France

14.30 - 14.55 Is exendin-4 a candidate for neuroprotection in the neonatal brain? Eridan Rocha-Ferreira, Sweden

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14.55 - 15.20 Preterm brain: MRI Manon Benders, the Netherlands

15.20 - 15.45 Cortical development during fetal and neonatal life Pierre Gressens, France

15.45 - 16.10 Neuroprotection in utero

Henrik Hagberg, Sweden-UK


ALBERT ROOM

14.30 – 16.30 PARALLEL SESSION 3: THE TWINS

Chairpersons: Ruben Quintero, USA; Asma Khalil, UK

14.30 – 14.50 TTTS versus TAPS: similarities and differences

Ruben Quintero, USA

14.50 – 15.10 Stage 1 TTTS: Conservative management or Laser surgery?

Yves Ville, France

15.10 – 15.30 Challenges in counselling and management of selective fetal growth restriction

Ruben Quintero, USA

15.30 – 15.50 How to avoid stillbirth in twins?

Asma Khalil, UK

15.50 – 16.10 Outcomes of singleton pregnancies reduced from twins compared with ongoing

twin pregnancy

Pavel Calda, Czech Republic

16.10 – 16.30 Screening and prevention of preterm birth in twins

Roberto Romero, USA

ST JAMES ROOM

14.30 – 16.30 PARALLEL SESSION 4: ACCRETA PLACENTATION: FROM DIAGNOSIS TO

MANAGEMENT

Chairpersons: Eric Jauniaux, UK; Corinne Hubinont, Belgium

14.30 – 14.50 FIGO classification and the use of standardised research protocol

Eric Jauniaux, UK

14.50 - 15.10 Prenatal and perinatal clinical diagnosis

Sally Collins, UK

15.10 - 15.30 The role of peri-partum hysterectomy

Aris Antsaklis, Greece

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15.50 - 16.10 Risks and benefits of conservative management

José M. Palacios-Jarquemada, Argentina

16.10 - 16.30 Discussion and take home message

VICTORIA ROOM

14.30 – 16.30 SPECIAL SESSION 1: STEM CELLS IN PERINATAL MEDICINE

Chairpersons: Bernard Thebaud, Canada; Ariadne Malamitsi-Puchner, Greece

14.30 - 14.55 Stem cells for the neonatal brain

Pierre Gressens, France

14.55 - 15.20 Mesenchymal stromal cell-derived exosomes for neonatal lung injury

Stella Kourembanas, USA

15.20 – 15.45 Personalized perinatal medicine and the potential of stem cells therapy

Gennady Sukhikh, Russia

15.45 - 16.10 Regenerative medicine in neonatology: A new hope

Bernard Thébaud, Canada


16.30 – 17.00 TEA BREAK

WHITTLE ROOM

17.00 – 18.30 PARALLEL SESSION 5: INDUCTION OF LABOR (IOL)

Chairpersons: Daniel Surbek, Switzerland; Kate Walker, UK

17.00 – 17.20 Where are we heading to in IOL?


17.20 – 17.40 ARRIVE study: what it tells us

Dan Farine, Canada

17.40 – 18.00 Mechanical methods for IOL

Janesh Gupta, UK

18.00 – 18.20 Delivery at term: When how and why

Kate Walker, UK


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FLEMING ROOM

17.00 - 18.30 PARALLEL SESSION 6: RESPIRATORY DISTRESS SYNDROME AND

BRONCHOPULMONARY DYSPLASIA

Chairpersons: Luc Zimmermann, the Netherlands, Suhas Kallapur, USA

17.00 - 17.20 Chorioamnionitis and BPD

Suhas Kallapur, USA

17.20 - 1740 CPAP failure

Luc Zimmermann, the Netherlands

17.40 - 18.00 BPD as a regenerative disease

Boris Kramer, the Netherlands

18.00 - 18.20 Vascular aspects in BPD

Irwin Reiss, the Netherlands


VICTORIA ROOM

17.00 – 18.30 PARALLEL SESSION 7: RANDOMIZED CONTROLLED TRIALS IN PREGNANCY

ASSESSING MATERNAL INFANT MEDICINE

Chairpersons: Ben Mol, Australia; Zarko Alfirevic, UK

17.00 - 17.25 Misleading RCTs and effect on guidelines: recent examples

Dan Farine, Canada

17.25 – 17.50 STRIDER prospective IPD

Zarko Alfirevic, UK

17.50 - 18.15 The difference between a woman and an airplane

Ben Mol, Australia


ALBERT ROOM

17.00 – 18.30 PARALLEL SESSION 8: HEALTH ECONOMICS IN MATERNAL-FETAL AND

NEONATAL MEDICINE

Chairpersons: Leila Adamyan, Russia; Gabriella Conti, UK

17.00 - 17.25 Economic stress and early programming of health and disease

Ariadne Malamitsi-Puchner, Greece

17.25 - 17.50 Cost effective innovations to improve newborn outcomes

Ranjan Kumar Pejaver, India

17.50 - 18.15 Medium and long-term effect of prenatal outcomes after economic stress

Gabriella Conti, UK

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ST JAMES ROOM

17.00 – 18.30 SPECIAL SESSION 2: THE ORIGINS OF NEURODEVELOPMENTAL DISEASE: FROM

CONCEPTION TO CHILDHOOD

Chairpersons: Despina Briana, Greece; Nicola Robertson, UK

17.00 - 17.20 Neurodevelopmental consequences of fetal and neonatal adaption to a

hypoxic environment.

Irwin K M Reiss, the Netherlands

17.20 - 17.40 Improving outcomes for preterm babies – the bigger picture.

Jan G. Nijhuis, the Netherlands

17.40 - 18.00 The intrauterine determinants of autism spectrum disorders

Despina Briana, Greece

18.00 - 18.20 Term NE – how can we augment protection from therapeutic hypothermia?

Nicola Robertson, UK


WHITTLE ROOM

18.30 – 19.00 HAPPY HOUR LECTURE

The metabolic ghetto

Jonathan Wells, UK

Saturday, 6th April 2019

ALBERT ROOM


Chairpersons: Graziano Clerici, Italy; Dan Farine, Canada

08.00 - 08.10 Association between perinatal death and bile acid levels in intrahepatic choles-

tasis of pregnancy: a systematic review

Daniele Di Mascio, Italy

08.10 - 08.20 Nov association between intrahepatic cholestasis of pregnancy and gestational

diabetes mellitus

Agata Majewska, Poland

08.30 - 08.40 The significance of hereditary thrombophilia in the reproductive dysfunction of

women from the Republic of Moldova

Diana Mitriuc, Moldova

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08.20 - 08.30 The association between exposure to non-steroidal anti-inflammatory drugs dur-

ing pregnancy and risk of subsequent miscarriage: a systematic review

Joanna Brecher, UK

08.40 - 08.50 Maternal smoking in pregnancy, fetal behavior and newborn state: An observa-

tional ultrasound study

Geidy Nolasco, USA

08.50 - 09.00 Interactive Medical Intelligence utilization to achieve optimal outcome for neo-

nate and mother

Gerard Pregenzer, USA

ST JAMES ROOM


Chairpersons: Irene Giardina, Italy; Aala Ebraishy, Egypt

08.00 - 08.10 Plasma lipids identify gestational diabetes mellitus in early pregnant stage

Ya Gao, China

08.10 - 08.20 Does the location of the placenta influence the degree of blood loss and histo-

pathological confirmation during the triple-P procedure?

Silvia Espuelas Malón, Spain

08.20 - 08.30 The Introduction of 3D/4D Based Spatio – Temporal Image Correlation (STIC) dur-

ing routine fetal anomaly scan improves rate of completion of fetal cardiac ex-

amination and decreases referral for fetal echocardiogram.

Ahmed Badreldeen, Quatar

08.30 - 08.40 First trimester ultrasound features associated with subsequent miscarriage: A pro-

spective study

Tracey Taylor, Australia

08.40 - 08.50 High multiplex digital PCR for NIPT and cancer mutation detection

Youxiang Wang, USA


VICTORIA ROOM


Chairpersons: Ola D. Saugstad, Norway; Pierre Gressens, France

08.00 - 08.10 The effectiveness of surfactant replacement therapy in late preterm neonates

with severe respiratory disorders. A retrospective cohort comparative study

Oleg Ionov, Russia

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08.10 - 08.20 Using umbilical cord blood for NICU admission laboratory tests: current practice

and literature review

Veronica Samedi, Canada

08.20 - 08.30 A clinical scoring system to predict the need for extensive resuscitation at birth in

very low birth weight infants

Juyoung Lee, South Korea

08.30 - 08.40 The early immunological diagnostics of neonatal sepsis with respiratory pathology

Marina Pukhtinskaya, Russia

08.40 - 08.50 The effect of parenteral nutrition arginine supplementation on early immune sys-

tem development in very preterm infants

Laura Burgess, UK

08.50 - 09.00 How is arginine intake from parenteral nutrition reflected in plasma arginine levels

of the preterm neonatal population ? a systematic review

Chandini Menon Premakumar, UK

WESLEY ROOM


Chairpersons: Manon Benders, the Netherlands; Sabita Uthaya, UK

08.00 - 08.10 Identification of parental needs in a neonatal intensive care unit: a first step in

the development of the NeoParent mobile application

Inge Tency, Belgium

08.10 - 08.20 Longitudinal changes of urinary biomarkers in late preterm infants during early

neonatal period

Sook-Hyun Park, South Korea

08.20 - 08.30 Postnatal determinants of blood pressure at 6.5 years of age in children born ex-

tremely preterm

Itay Zamir, Sweden

08.30 - 08.40 Feasibility of umbilical cord blood collection in neonates at high risk of brain

damage

Angela Segler, Germany

08.40 - 08.50 Neonatal neuroprotective effect of lactoferrin in a rat model of prenatal

hypoxia

Vadim Vasilyev, Russia


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FLEMING ROOM 09.00 - 11.00 PLENARY SESSION 2: THE CHALLENGE OF IUGR FETUS AND NEWBORN

Chairpersons: Gerard H.A. Visser, the Netherlands; Jason Gardosi, UK

09.00 - 09.20 Is the threshold for viability depending on fetal size?

Neil Marlow, UK

09.20 - 09.40 Management of early fetal growth restriction

Christoph Lees, UK

09.40 - 10.00 Early delivery of fetal growth restriction; are antenatal steroids useful?

Umberto Simeoni, Switzerland

10.00 - 10.20 Improving antenatal detection of fetal growth restriction:victories and challenges

Jason Gardosi, UK

10.20 - 10.40 Management of late fetal growth restriction; many unsolved issues


10.40 - 11.00 Long term follow-up of fetal growth restriction

Fatima Crispi, Spain

11.00 - 11.30 COFFE BREAK

FLEMING ROOM

11.30 - 13.00 CO-PLENARY SESSION 3: NUTRITION AND EARLY FEEDING IN PERINATAL PERIOD

Chairpersons: Umberto Simeoni, Switzerland; Neena Modi, UK

11.30 - 11.50 The evidence base for current recommendations for feeding extremely preterm

neonates Cheryl Battersby, UK

11.50 - 12.10 Current recommendations for parenteral nutrition of extremely preterm neonates

Sabita Uthaya, UK

12.10 - 12.30 Biomarkers to guide neonatal nutrition research Umberto Simeoni, Switzerland

12.30 - 12.50 Improving neonatal nutrition: how to resolve urgent uncertainties Neena Modi, UK


22

WHITTLE ROOM

11.30 - 13.00 CO-PLENARY SESSION 4: PREVENTION IS BETTER THAN CARE: THE RH DISEASE

PARADIGMA

Chairpersons: Gerard H.A. Visser, the Netherlands; Gian Carlo Di Renzo, Italy

11.30 - 11.45 Introduction of Rh disease: 50 years of Rh eradication


11.45 - 12.00 Prevention of Rh disease: global figures


12.00 - 12.20 Fetal Rh isoimmunization: what to do?

Gennady Sukhikh, Russia

12.20 - 12.35 Neonatal Rh disease: still a burden

Marcela Contreras, UK

12.35 – 12.50 The forthcoming 50 years: global strategies



VICTORIA ROOM

11.30 - 16.30 SPECIAL SESSION 3 - FETAL THERAPY - 1st PART

Chairpersons: Ruben Quintero, USA; Ramen Chmait, USA

11.30 - 12.00 CCAM/CPAM and other fetal lung lesions

Eftichia Kontopoulos, USA

12.00 - 12.30 Percutaneous fetoscopic treatment of myelomeningocele: The US Fetus trial

Ramen Chmait, USA

13.00 – 14.30 BREAK

VICTORIA ROOM

11.30 - 16.30 SPECIAL SESSION 3 - FETAL THERAPY - 2nd PART

Chairpersons: Ruben Quintero, USA; Ramen Chmait, USA

12.30 - 13.00 Management of fetal lower urinary tract obstruction (LUTO).

Ruben Quintero, USA

14.30 – 15.00 Discordant anomalous monochorionic twins

Eftichia Kontopoulos, USA

15.00 – 15.30 Assessment and management of selective intrauterine growth restriction (SIUGR)

Ramen Chmait, USA

23

15.30 – 16.00 Laser therapy for twin-twin transfusion syndrome. challenging cases

Ruben Quintero, USA


FLEMING ROOM

14.30 - 16.30 PARALLEL SESSION 9: NEW TRENDS IN NEONATOLOGY

Chairpersons: Christian P. Speer, Germany; Stella Kourembanas, USA

14.30 - 14.55 The first golden minutes: The role of sustained inflation and late cord clamping

Haresh Kirpalani, USA

14.55 – 15.20 Work of breathing and thoracoabdominal asynchrony

Anne Greenough, UK

15.20 - 15.45 Mesenchymal stem cells: Magic cure for cerebral injury of preterm infants?

Won-Soon Park, South Korea

15.45 - 16.10 Visualization of pain perception of preterm infants

Rebeccah Slater, UK


WHITTLE ROOM

14.30 - 16.30 PARALLEL SESSION 10: CESAREAN DELIVERY

Chairpersons: Mike Robson, Ireland; Vincenzo Berghella, USA

14.30 – 14.50 Caesarean section - classification and indications

Mike Robson, Ireland

14.50 – 15.10 Cesarean technique part 1: intraoperative preparation, and from skin to baby


15.10 - 15.30 Cesarean technique part 2: From baby to skin closure and more

A. Dhanya Mackeen, USA

15.30 – 15.50 Accreta management

Huixia Yang, China

15.50 – 16.10 Cesarean section in twins

Victor Radzinsky, Russia

16.10 – 16.30 The care for the bleeding obstetric patient addressing inequality in resources and

training

Offer Erez, Israel

24

ST JAMES ROOM

14.30 - 16.30 PARALLEL SESSION 11: PRENATAL DIAGNOSIS: WHAT IS NEW?

Chairpersons: Gordon Smith, UK; Giuseppe Rizzo, Italy

14.30 - 14.55 Update on the use of invasive technique in prenatal diagnosis

Tullio Ghi, Italy

14.55 - 15.20 Whole exome sequencing in prenatal diagnosis

Mark Kilby, UK

15.20 - 15.45 NIPT, where next?

Maria del Mar Gil Mira, Spain

15.45 - 16.10 Abnormalities missed because of NIPT

Mark Evans, USA

16.10 - 16.30 Classification and management of fetal lower urinary tract obstruction

Katia Bilardo, the Netherlands

ALBERT ROOM

14.30 - 16.30 SPECIAL SESSION 4: HOT NEONATAL TOPICS

Chairpersons: Josef Neu, USA; Eduardo Bancalari, USA

14.30 - 14.55 Antenatal steroids: benefits, risk and new treatment strategies

Alan Jobe, USA

14.55 - 15.20 Oxygen in the premature: a difficult balance

Eduardo Bancalari, USA

15.20 - 15.45 Sustained Inflation in the delivery room: results of the SAIL trial

Haresh Kirpalani, Canada

15.45 - 16.10 Donor human milk: Is it a panacea?

Josef Neu, USA


16.30 – 17.00 TEA BREAK

FLEMING ROOM

17.00 - 18.30 PARALLEL SESSION 12: NEW ISSUES ON PRETERM BIRTH AND PREMATURITY

Chairpersons: Sonia Hassan, USA; David Sweet, UK

17.00 - 17.20 Biomarkers for preterm birth prediction


17.20 - 17.40 Fetal monitoring: dilemmas and practice recommendations

Edwin Chandraharan, UK

25

17.40 - 18.00 Omega 3 in the prevention: there is evidence?

Zarko Alfirevic, UK

18.00 - 18.20 Delayed cord clamping

William Tarnow Mordi, Australia


WHITTLE ROOM

17.00 – 18.00 PARALLEL SESSION 13: NEONATAL OUTCOME: WHICH MATTERS?

Chairpersons: Luc Zimmermann, the Netherlands; Irina Soldatova, Russia

17.00 – 17.25 The role of perinatal centers in reducing infant mortalities in Russia

Irina Soldatova, Russia

17.25 – 17.50 Euro-Peristat data: what have we learned?

Jan Nijhuis, the Netherlands


ST JAMES ROOM

17.00 - 18.30 SPECIAL SESSION 5 – MATERNAL HEMODINAMICS: BEYOND BLOOD PRESSURE

SCREENING IN PREGNANCY

Chairpersons: Enrico Ferrazzi, Italy; Christopher Lees, UK

17.00 - 17.15 Heart, arterial and the venous compartment changes in pregnancy

Wilfried Gyselaers, Belgium

17.15 - 17.30 Pre-pregnancy and pregnancy hemodynamic in hypertensive disorders

of pregnancy

Christopher Lees, UK

17.30 - 17.45 Maternal hemodynamics and HDP in pregnancy and postpartum - molecular

markers and placental correlates

Enrico Ferrazzi, Italy

17.45 - 18.00 Maternal hemodynamics in severe IUGR

Herbert Valensise, Italy

18.00 - 18.15 Fetal growth in chronic hypertension and preeclampsia

Tullio Ghi, Italy

18.15 - 18.30 Tailored antihypertensive therapy

Marc Spaanderman, the Netherlands

26

WHITTLE ROOM

18.30 – 19.00 HAPPY HOUR LECTURE

How much is medicine, how much is social developments in getting better?

Gerard H.A. Visser, the Netherlands

WHITTLE ROOM

19.00 CLOSING

27

ATELIERS:

5th April 2019

09.00 - 11.00 A1: MUSIC AND MUSICOTHERAPY IN PERINATAL PERIOD

Birgit Arabin, Germany; Enrico Granieri, Italy

11.30 - 13.00 A2: SMALL PROBLEMS IN THE NEONATAL UNIT AND NICU

Nadja Haiden, Austria

11.30 - 13.00 A3: PHYTOTHERAPY

James S. Mclay, UK

14.30 – 16.00 A4: SMALL PROBLEMS IN PREGNANCY AND LABOUR

Yariv Yogev, Israel; Enrico Ferrazzi, Italy

6th April 2019

09.00 – 10.30 A5: HOW TO WRITE A GOOD SCIENTIFIC PAPER

Janesh K. Gupta, UK

11.30 – 13.00 A6: HOW TO COLLABORATE AND COMMUNICATE WITH PARENTS

IN CRITICAL DECISION MAKING SITUATIONS

Silke Mader, Germany

Multidisciplinary antenatal and perinatal palliative care

Fauzia Paize, UK

How can we healthcare professionals make the parents journey

bearable in the neonatal period?

Roisin Mckeon-Carter, UK

How parents can be involved in making critical care decisions:

a parents perspective

Silke Mader, Germany

14.30 - 16.30 A7: PAIN IN THE NICU

Ricardo Carbajal, Portugal; Marsha Campbell-Yeo, Canada

17.00 - 18.30 A8: NON INVASIVE RESPIRATORY SUPPORT TO THE NEWBORN

Peter Davis, Australia; Haresh Kirpalani, Canada

17.00 - 18.00 A9: EXERCISE IN PREGNANCY


2 world congress on maternal fetal ......1 2nd world congress on maternal fetal neonatal medicine...

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