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IntroductionResults and Methodologies
Locating the Lesions Psychological Tests
Summary and Conclusions
Nicole Neil
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Introduction
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Subject Age of Injury Age at Test Source of InjuryBeth Birth 12 Hypoxia (birth trauma)
Jon 4 16 Hypoxia (convulsive seizures)
Kate 9 19 Hypoxia (seizures)
Mudra Bhatt
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Hippocampal System
Episodic Memory
Hippocampal System
EpisodicMemory
SemanticMemory
SemanticMemory
Underlying Cortices
Nicole Neil
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Methods Results
Volumetric Measurements
Hippocampus abnormally
small
T2 Relaxometry Remaining hippocampal
tissue severely compromised
Proton Magnetic Spectroscopy
Temporal Lobe normal
Molly O’Brien & James Guse
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Parental Questionnaire Used Riverhead Mead Test to confirm
degree of impairment:
spatial temporal episodic
Molly O’Brien & James Guse
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Copy of the Rey-Osterreith Complex Figure and 40-min delayed reproduction of it.
Normal control, copy and delayed reproduction by a typical 13-year-old.
Psychological TestsMolly O’Brien & James Guse
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Molly O’Brien & James Guse
VIQ PIQ MQ
0
20
40
60
80
100
120Multiple IQ Comparisons
Beth
Jon
Kate
Normal
Standardized tests for IQ were done on all three children and compared to norms (green),
VIQ: Verbal Intellgence QuotientPIQ: PerformaceMQ:Memory Quotient
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Molly O’Brien & James Guse
Working Memory
Combined foreward and reverse w.m. span
Normal
Kate
Jon
Beth
Working memory is at par with normal controls (green)!
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Semantic (Intact)
Episodic (Damaged)
Verbal IQ Parent Report
Reading Comprehension Rey-Osterreith Complex Figure
Spelling* (exception Jon) Verbal Recall Tests
Richa SharmaMolly O’Brien & James Guse
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Hippocampal System
Episodic Memory
Hippocampal System
EpisodicMemory
SemanticMemory
SemanticMemory
Underlying Cortices
Richa Sharma
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Richa Sharma