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Department of Dermatology ST VINCENTS HOSPITAL MELBOURNE FITZROY AUSTRALIA BIENNIAL REPORT 2001-2002

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Page 1: Department of Dermatology

Department of DermatologyST VINCENTS HOSPITAL MELBOURNE FITZROY AUSTRALIA

BIENNIAL REPORT 2001-2002

Page 2: Department of Dermatology
Page 3: Department of Dermatology

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It is remarkable how time seems to go more rapidly the older we get. In the case of the academicDepartment of Dermatology at St. Vincent’s Hospital Melbourne it is hard to believe that we arenow eight years old. But perhaps the feeling that time has passed quickly is a reflection of howmuch has been achieved over that time.

In this fourth Biennial Report we give details of what we have achieved in the last two years, specificallyrelated to the Operational Plan 2000-2004. These are in the areas of Clinical Services, Teaching andResearch. As you will see, we have an extremely active and dedicated team working in different ways ineach of these areas.

Within the administrative structure, plus the service and research staff, we have a stable team who have allbeen with us since the last Biennial Report, and a substantial proportion of whom have been with us formany years. This continuity creates a very stable environment to support the productive endeavours of ourteam.

In the Service area we have now moved into the new outpatient facilities which have been designed tofacilitate the delivery of care in the ambulatory setting. This has worked out to be very satisfactory for notonly for the staff providing the care, but also for the patients receiving it. The presence of a computerterminal on each of the desks has supported the upgraded Dermatology Database. The PhotobiologyServices provided under the guidance of Chris Baker and Peter Foley have been substantially enhanced bythe addition of a new solar simulator, kindly provided with funds from the St. Vincent’s Hospital Foundation.This group is now one of the large photobiology centres in the world. Other specialised services include thevascular/lower leg ulcer services of Robert Kelly, the cutaneous lymphoma interest of Chris McCormack andthe immunobullous diseases interest of Belinda Welsh. They are providing a highly specialised component ofdermatological care which is appropriate for a tertiary teaching institution of the level of St. Vincent’sHospital Melbourne. Of course, we still provide a general dermatological service underpinning the highlydeveloped subspecialties.

You will see in the Teaching section the wide range of education we provide from public education programsthrough to medical student and postgraduate medical practitioner training. St. Vincent’s Hospital Melbournehas a very special clinical school with the medical students frequently taking the large majority of prizes in thefinal year medical exam. It is an indication of the calibre of students who want to come into this teach-ingenvironment and certainly is revealed when we have them involved in dermatology as part of their training.

Like any academic department the research is an important driving force that determines directions bothnow and in the future. The major arms, as you can see in the body of this Report, include the HealthServices Research group headed by Robin Marks and Jan Campbell, along with the Hair Research groupmanaged by Rod Sinclair and the Photobiology Research group managed by Peter Foley. Each of thesegroups has research/project staff helping to expand their output.

The nature and extent of the work of the Department means that we are now not only well known inVictoria, but are seen as a major national group in the areas of expertise of this Department. We also havean international reputation with members of the Department being invited to present papers at many of themajor international dermatological meetings throughout the world. The recent appointment as President ofthe International League of Dermatological Societies was a feather in the cap for Australian dermatology ingeneral and the Department in particular.

In summary, the enthusiastic and very positive approach of all members of the Department has resulted in anoutstanding record, once again, for the last two years. We have received support for our work from manydifferent groups and individuals. I am sure they will be proud of what has been done on their behalf inimproving the outlook for people suffering from skin conditions in our community.

I commend this Report to you.

Robin Marks

Professor/Director of Dermatology

February 2003

Director’s Report

Page 4: Department of Dermatology

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The clinical arm of the Department of Dermatology has continues to be an active area in the

delivery of clinical services, medical student teaching and registrar training. The medical, nursing

and office staff, continue to strive to deliver excellence in dermatological care. In the 2001 – 2002

biennium, in addition to inpatient admissions and consultations, 10,927 outpatient services were

provided by the Department.

The clinical service is an integral component of the Department complimenting and providing crucial support

for the research and teaching activities. Patients attending our clinics continue to come from metropolitan

Melbourne, rural Victoria and interstate, with referral source ranging from local general practitioners and the

emergency department to other dermatologists and specialists. The work of the Department continues to be

well supported by the Hospital administration and is therefore able to provide a range of consultative services

to other units and departments.

The Department offers a range of general Dermatological services and manages a all common skin problems

as well as providing opinion and treatment for more complex and challenging problems. Expertise in several

super-speciality areas is provided. These include cutaneous lymphoma (Dr Christopher McCormack with

valuable assistance from Professor Miles Prince and Dr Gail Ryan, Peter MacCallum Cancer Institute), vascular

and wound healing service (Dr Robert Kelly) and immunobullous disorders (Dr Belinda Welsh).

The photodermatology clinic, under the direction of Dr Peter Foley and myself, continues to provide a unique

service investigating sun sensitivity skin disorders. The photodermatology data base now encompasses 9

years of clinical experience and has undergone further development and refinement. In 2001 we

commissioned the Solar Simulator which was purchased through a generous donation from the St. Vincent’s

Foundation. The solar simulator is now an integral part of the phototesting regimen. Our clinical nurse,

Leonie Hill, continues to perform phototesting and phototherapy services. Her exper-ience and expertise in

this area is unique.

The Department maintains a close working relationship with the skin and Cancer foundation.

The Foundation registrar and St Vincent’s Registrar exchange positions mid year to provide a broader

experience in clinical Dermatology. The Hospital has two dedicated Dermatological Trainees. These are the St

Vincents Hospital Registrar and the Professorial Registrar. In addition, a number of registrars in the Victorian

training program rotate through clinics at St Vincent’s, providing addition clinical support and gaining

valuable training experience. Finally, the entire clinical team and in particular Professor Robin Marks and

Dr Andrew Michaelides play an important role in the undergraduate training program.

In July 2002, a new outpatient clinic area was opened. This is a state of the art facility on the ground floor

of the Daly wing, with a comfortable well designed clinic area including PC facilities and internet access in all

consulting rooms. In addition, the Department has a dedicated area for phototherapy and phototesting

facilities.

The upgraded facilities will allow the clinical service arm of the Department continue the high standard of

services offered. To further develop patient services, the Department has recently received a grant from the

William Joseph Payne Trust to develop a system of digital imaging of skin conditions and integration of this

record with the patient’s file. This system combined with our new outpatient facilities should help in the

diagnosis and monitoring of a patient’s condition.

Once again, as Director of Clinical Services in Dermatology, I wish to thank all members of the Department

and associated staff for their commitment and effort.

Dr Chris Baker

Director of Clinical Dermatology

February 2003

Clinical Services

Page 5: Department of Dermatology

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Patient Statistics

1995/1996 1997/1998 1999/2000 2001/02

TYPE OF CLINIC n= n= n= n=

Dermatology 7876 7593 8638 6556

Dermatology Investigations 345 534 411 1044

PUVA & UVB 1784 2091 1949 2687

Photobiology 203 428 429 640

TOTAL 10,208 10,646 11,427 10,927

OUTPATIENT ATTENDANCES 1995-2000

Rate of Disease Groups for 1999/2000 and 2000-2002

*Other conditions include: mycosis fungoides, pruritis, nodular prurigo, ulcers, keratosis pilaris, lichen planus, bulous pemphigold, scars and patients with diagnoses pending.

Tumours

Dermatitis

Melanocytic naevi

Acne

Fungi

Psoriasis

Viral

Allergic

Other naevi

Bacterial

Hair

Pigment

Nails

Parasites

*Other conditions

1999/2000

2001/02

0 5 10 15 20 25 30

Page 6: Department of Dermatology

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Patient Statistics

< Staff at the Skin & Cancer Foundation Skincare Clinic

PATIENT REFERRALS

1995 1995 1996 1997 1998 1999 2000 2001 2002% % % % % % % % %

General practitioner

Other outpatient clinic

Dermatologist

*Other

Hospital inpatient

63.6 63.6 72.2 75.2 71.0 6.8.8 62.9 63.1 66.0

21.3 21.3 13.6 10.1 8.4 8.7 10.9 10.2 9.2

8.6 8.6 7.0 7.5 8.6 12.1 17.9 14.8 16.2

6.5 6.5 6.2 6.4 10.8 9.5 7.7 11.2 7.4

N/A N/A 1.0 0.8 1.1 0.8 0.9 0.6 1.1

*Other hospitals, health care facilities, correctional health services.

DIAGNOSIS PROPORTION (%)

1995/1996 1997/1998 1999/2000 2001/02% % % %

Solar Keratosis

Unspecified Dermatitis

Fungal Infection

Psoriasis

Seborrhoeic Keratosis

Melanocytic Naevi

Basal Cell Carcinoma

Warts

Acne

Atopic Dermatitis

Other Inflammatory Dermatoses

Squamous cell carcinoma

TOP 10 DIAGNOSES

9.0 8.6 7.4 8.5

7.1 6.1 5.6 6.0

6.3 6.8 6.4 5.7

5.9 5.3 4.7 5.2

5.6 5.5 5.7 5.0

5.6 7.1 6.9 7.0

5.0 3.9 4.8 6.4

4.5 3.2 2.9 2.3

3.8 5.1 4.6 3.7

3.4 3.1 - -

- - 2.7 -

3.3

Page 7: Department of Dermatology

Dermatology education is one of the core activities of the Department with our target audience

including medical students, general practitioners, dermatology registrars, paramedical staff and

the general community. The many facets are highlighted in the details of this Report.

The Department had substantial input into the development of the new University of Melbourne medical

curriculum. This not only involved redefining the core curriculum for medical students, but also inserting

a dermatology component into various semesters over the period of the course. Medical students from the old

curriculum, and also the new curriculum, are still receiving clinical teaching in the St. Vincent’s Hospital clinics

and at the Skin and Cancer Foundation of Victoria as they have identified this as an important contribution to

their development as a medical practitioner. With the involvement of Rosemary Nixon and the Occupational

Dermatology Research and Education Centre it is hoped to have involvement of Monash University medical

students before long.

General practitioner education was enhanced by the new booklet on diagnostic procedures developed by the

Department and mailed to every general practitioner in Australia. It was a sequel to the first book on treatment

of common skin conditions and will be completed by a third book on diagnosis, each produced within the

Department. Department members have participated in a wide range of teaching sessions for general

practitioners including those arranged by the Skin and Cancer Foundation, the Royal Australasian College of

General Practitioners, the Essex series and by the GP divisions throughout Victoria. General practitioner

teaching remains a very high priority of the Department.

Registrar teaching at St. Vincent’s Hospital continues to be strong with all Victorian candidates for fellowship of

the Australasian College of Dermatologists being successful in the last two years. The Department has

coordinated a program of tutorials on clinical dermatology and dermatopathology at the Skin and Cancer

Foundation of Victoria. The regular Thursday morning teaching sessions at St. Vincent’s Hospital, combined

with Royal Melbourne Hospital, have continued to create interest for registrars and dermatologists.

Members of the Department have published a large variety of educational articles in various medical textbooks

and journals directed at medical students, general practitioners and dermatology registrars. The public

educational resources of the Department developed for primary and secondary schools and Maternal and Child

Health centres have extended the reach of the Department widespread into the community, as have various

articles written by members of the Department in response to media approaches.

In summary, the Department covers a very wide range in its teaching activities all of which we hope in the long

term will contribute to improved practice by medical professionals and better access, understanding and care

for those in the community with disease affecting their skin.

Dr Rodney Sinclair

Senior Lecturer in Dermatology

February 2003

Teaching 2001/2002

5

Page 8: Department of Dermatology

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Teaching 2001/2002

> Staff of the Friday morningSpecial Investigative andPhotodermatology Clinic

GENERAL PRACTITIONER LECTURES/WORKSHOPS

Topic Date Meeting

Acne Therapies/Skin Biopsy April 2001 Yarra Valley Division of GPs Techniques (PF)

Advanced psoriasis (PF) June 2001 GP update series (Skin and Cancer Foundation / Essex Pharma) Novotel Glen Waverley

Non-melanoma skin cancer (RM) August 2001 Dermatology Update Conference for General Practitioners, St. Vincent’s Hospital

An Approach to Dermatology (PF) June 2001 Essex Pharma Lecture Series for GPs

Hair and Nails (PF) August 2001 Cabrini Medical Centre GP lecture series

Pigmented Lesions (RM) November 2001 Goulburn Valley Division of General Practice, Shepparton

Paediatric Dermatology (CB) May 2002 Whitehorse Division of GPs

Non-melanoma skin cancer (RM) May 2002 Dermatology Update Conference for General Practitioners, SVHM

Acne, Warts and Hair Problems (PF) July 2002 GPEA Training Program Evening Lecture Series, Melbourne

Practical Procedures in Dermatology (CB) August 2002 Yarra Valley division of GPs

The Art of Medicine (RM) February 2001 IV years

Sunscreens & skin cancer (RM) April 2001 Royal Victorian Eye & Ear Hospital lecture

Red Scaly Rashes (CB) May 2001 6th Year Medical Students - SVHM

Sunscreens & skin cancer (RM) March 2002 Royal Victorian Eye & Ear Hospital lecture

New curriculum PBL 2001/2002 4th Year Medical Students - SVHM

Hair diseases 2001/2002 Royal Victorian Eye & Ear Hospital lecture

Weekly /fortnightly clinic attendances 2001/2002 SVHM 6th Year students(all consultants)

MEDICAL STUDENTS LECTURES

Page 9: Department of Dermatology

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JOINT RMH & SVHM TEACHING SESSIONS - DERMATOLOGY REGISTRARS & DERMATOLOGISTS

2001

March Photodynamic Therapy for Skin Malignancies Speaker: Dr Peter Foley

March Approach to Urticaria Speaker: Dr Richard O’Brien

April Flap Prefabrication and Tissue Engineering Speaker: Professor Wayne Morrison

May Research projects in the Department of Dermatology

- current update

June 1. Incomplete BCC excision. Speaker: Dr Tam Dieu

2. Melanoma research

July Warfarin Necrosis Speaker: Dr Cate Scarff

August Immunosuppressive and immunomodulatory drugs Speaker: Associate Professor Tom Kay

September Cutaneous lymphoma: Update on the Melbourne Speakers: Drs Lee Mei Yap & Cate Scarff

experience

October 1. Cutaneous surgery of the lower leg. Speaker: Mr Tony Pennington

2. What ever happened to Eusol?

November Using cyclosporin and managing side effects Speaker: Dr Ian Fraser

2002

February Cases, quizzes and discussions

March Retinoids, lipids and the skin

April Cardiology concerns in cutaneous surgery: Speaker: Dr Peter Kistler

Heart valves, anticoagulants, pacemakers and long CT

May Special presentation by Visiting Fellow, Dr Susan Burge,

Oxford University, UK

July Nail Surgery Speaker: Mr Bruce Johnstone

August Update on the Role of Sentinel Node Biopsy Speaker: Mr Michael Henderson

in Melanoma

Adjuvant Radiotherapy in Melanoma Speaker: Dr Jill Ainsley

October Leprosy and Lupus Vulgaris Speakers: Drs Lee Mei Yap and

Veerle Verlinden

November Pruritis ani - a sore point for doctors Speaker: Mr. Joe Tjandra

Page 10: Department of Dermatology

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Teaching 2001/2002

Australian Doctor ‘Concepts in Skin’ Series (RM) 2001

A measured response to tinea January

Perioral inflammatins March

Itch treatment up to scratch May

Helpful advice on scaly scalps July

Sensitive soles present problems August

Making the call on common conditions November

Australian Doctor ‘Concepts in Skin’ Series (RM) 2002

Combination of science and art helps diagnosis March

Best way to shine in melanoma diagnosis April

Which treatment? Follow this guide June

Critical to diagnose dermatitis at work (RM and Rosemary Nixon) August

Occupational Dermatology – RM and Rosemary Nixon) October

How to stop treatment in Dermatology

Everybody Magazine (RM)

Don’t touch! Common environmental factors can play Springhavoc with our skin

Stress & the skin Summer

Sensitive skin - the cure may be as simple as switching products Autumn/Winter

The 10 biggest sunscreen mistakes Spring

TEACHING THROUGH GP JOURNALS AND LAY MAGAZINES

Page 11: Department of Dermatology

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The research activities supported by the Department of Dermatology are diverse and wide-ranging.

Projects conducted over the past two years reflect this diversity, with staff having qualifications and

experience in dermatology, epidemiology, health information management, social research, quality

performance measurement, health promotion and education, data management and project

management. Projects carried out during 2001 and 2002 are reported under the headings of

Epidemiology and Health Services, Health Promotion and Education, Hair, Photobiology and Clinical

Trials.

A two-year study of a cohort of psoriasis patients completed in 2000 was supported by an additional qualitative

component involving face-to-face interviews with a small group of participants which was conducted during

20001. A study involving a cohort of patients with atopic dermatitis collected information on the impact that

inflammatory skin conditions can have on the individual and community.

The field of health promotion and community education has increased with the development of statewide

education programs on common skin diseases for all secondary and primary schools in Victoria. A program for

Maternal and Child Health nurses and their clients was also developed and distributed to all Maternal and Child

Health centres throughout Victoria during 2002. Each of these programs has been developed in conjunction

with the appropriate professional organisation and the high rate of use within each group reflects the

consultative component and the research base underpinning these programs.

The development of the Standardised Dermatology Database, which has been trialled successfully at St

Vincent’s Hospital over the past year, has the potential to collect data from all dermatology clinics and thus

contribute to epidemiology, research and quality improvement projects while also facilitating the teaching of

trainees.

Undergraduate Health Information Management students from La Trobe University have completed their

practical placements within the department. They have been involved in a variety of projects including auditing

clinical databases and quality management activities.

Rod Sinclair, who specialises in hair and nail conditions, heads a team of Clinical and Genetic researchers

comprising Masters of Medicine students Jack Green, Keng-Ee Thai, and Shannon Harrison, and also Bachelor

of Medical Science student Desmond Gan. They have worked on a number of projects related to a variety of

forms of alopecia as part of their degrees. This vibrant team has contributed much that is new and exciting to

the world research into hair disorders.

Peter Foley’s team who conduct research into the uses of Photobiology in Dermatology includes Chris Baker, Lee

Mei Yap and Bachelor of Medical Science student, Jonathan Ng. Peter is also responsible for an increasing

number of clinical trials involving new treatments for dermatological conditions which are conducted at SVHM

and the Skin & Cancer Foundation.

Over the past two years a number overseas visitors, in particular Andrew Messenger (UK), Veerle Verlinden

(Belgium) and Mirjam Werwenike (Netherlands) have swelled the ranks of the research team and added an

international flavour to the diverse range of talents within the Department.

The group of people who comprised the research team during 2001 and 2002 have built on the work of all

those who contributed to the first eight years of this unique Department and accomplished much that is new

to facilitate the future development of the Department and Dermatology.

Jan Campbell

Department Manager,

February 2003

Research,Health Services &

Community Education

Page 12: Department of Dermatology

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EPIDEMIOLOGY AND HEALTHSERVICES RESEARCH

A one year study of the morbidity, severity

and cost of having atopic eczema in Australia

Nicole Harman, Jan Campbell, Maria Moore, Anne

Plunkett, Robin Marks

A one year study aimed to determine the

morbidity, severity and cost of having atopic

eczema in Australia. A total of 85 participants

were recruited. Each participant attended a

baseline interview where an introductory

questionnaire, Dermatology Life Quality Index

(DLQI) and Modified Rajka and Langeland Severity

Assessment (MRLSA) were completed. Participants

then had a skin examination performed by a

dermatologist to determine the severity of their

condition. Following this there were six follow ups,

one every two months where participants were

sent and asked to complete the DLQI and MRLSA

questionnaires on the morbidity and severity of

their atopic eczema and a diary of their atopic

eczema costs and health care consultations.

Of the 53 (64%) participants who returned all

follow up questionnaires, 45% felt that their skin

had been itchy, sore, painful or stinging, 36%

spent over 10 minutes applying daily treatments,

28% were influenced by the clothes worn, 21%

felt embarrassed or self conscious because of their

skin and 15% had problems with the treatments

for their skin i.e. making their home messy.

Date Commenced: December 1998

Date Completed: March 2001

Progress of Project: Report written,

publication in progress

Funding Source: Core budget; Scientific

Fund Australasian College

of Dermatologists

A Pilot Study To Investigate The Association

Between Fungiform Papillary Glossitis And Atopy

Cate Scarff, Jan Campbell, Robin Marks

Patients often report symptoms related to the

tongue. Unfortunately, our understanding of these

is often limited. While some conditions such as

geographic tongue are well described, they do not

explain the symptoms reported by patients in all

cases. The survey, which recruited 84 subjects,

investigated whether atopic subjects reported more

symptoms and had a different appearance of the

tongue compared with non-atopic subjects. This

involved a questionnaire about medical history and

symptoms in the mouth, an examination of the

tongue and skin prick testing to four common

aeroallergens. A classification system was

developed to record the spectrum on features seen

on the tongue. Results showed atopic subjects

tended to have an appearance of the tongue that

was clustered to one end of the spectrum. The

number of non-atopic subjects who volunteered

was small, but their examination findings were

more evenly distributed. Greater numbers of non-

atopic subjects need to be recruited to see if this

trend is confirmed.

Date commenced: January 2001

Progress of project: Pilot completed December

2001; Report written.

Funding source: Core budget, St. Vincent’s

Hospital Melbourne

Research grant

Research Projects

Page 13: Department of Dermatology

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A continuation of a study investigating the

association between fungiform papillary

glossitis and atopy

Lee Mei Yap, Veerle Verlinden, Jan Campbell,

Peter Foley, Robin Marks

200 subjects were recruited from St. Vincent’s

Hospital Melbourne and the Skin and Cancer

Foundation. Data regarding personal and family

history of atopy, mouth discomfort, burn response

and inflammatory changes of the fungiform

papillae were collected to determine if there is an

association between fungiform papillary glossitis

and atopy.

Date commenced: August 2002

Date completed: November 2002

Progress of project: Data being analysed.

Funding source: Core budget

A Qualitative Study Of Having Psoriasis In

Australia: The Patient’s Viewpoint

Jan Campbell

This study aimed to gain further information on the

morbidity that affects psoriasis sufferers, through

individual face-to-face interviews with a sample of

6 participants who had completed the Psoriasis and

Health Survey. The interviews provided them with

the opportunity to expand on their own responses

and further discuss the quality of life issues they

each experience in relation to having psoriasis.

Qualitative research, such as this, complements and

contributes to the interpretation of the quantitative

data that have been collected during the survey.

Date commenced: September 2001

Progress of Project: Report in progress

Funding sources: Core Budget

HEALTH PROMOTION AND EDUCATION

Skin - an education program for Maternal and

Child Health

Kate Merlin, Jan Campbell, Maria Moore,

Robin Marks

This program targeted Maternal and Child Health

(MCH) nurses and the parents/guardians of babies

and children who attend MCH centres in Victoria.

The program aimed to improve the awareness and

knowledge of those who advise parents/guardians

about children with common skin conditions. The

information concentrates on the prevention of

many of these conditions, as well as treatment

where appropriate, to improve the management

and outcome of these children.

The program was developed in consultation with

MCH nurses. Nurses completed surveys which

determined the most suitable resources and

program strategies. The resources were trialled in a

selection of MCH centres and feedback was

provided through surveys and telephone interviews.

The resources, comprising a folder with

information and photographs for nurses and

information sheets which could be photocopied for

parents/guardians, were then modified, printed and

distributed to all Victorian MCH nurses.

Date commenced: September 2000

Date completed: May 2002

Progress of Project: Completed

Funding sources: Ian Potter Foundation,

George Alexander

Foundation, RE Ross Trust,

Gwendolyn Holly Bequest

Page 14: Department of Dermatology

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Skin - an education program for Primary

Schools

Kate Merlin, Jan Campbell, Maria Moore,

Robin Marks

This program targets children in the upper level,

grades 5 and 6, of primary schools in Victoria, their

teachers and their parents. The program aims to

improve their knowledge of the nature and

management of particular skin conditions, shown

in previous Department research to be common in

this age group. A primary school teacher was

employed to assist in the development of the

education resources and a selection of teachers

completed surveys to determine the most suitable

resources and program strategies. The resources

were trialled in a group of primary schools and

teachers and students provided feedback through

surveys and telephone interviews. All Victorian

primary schools were offered a free resource kit in

December 2002 and these will be delivered to

schools in early 2003. The kit comprises three

components: a resource book containing

information about the skin and common skin

conditions plus lesson plans and activities; 11

information cards about common skin conditions

for use by students; and four posters highlighting

important information about the Skin,

Inflammatory Conditions, Infections and

Infestations.

Date commenced: September 2000

Date completed: December 2002

Progress of Project: Resource developed;

Distribution underway

Funding sources: Jack Brockhoff Foundation,

Felton Bequest

Development, Implementation and Evaluation

of Internet Web site

Nicole Harman, Jan Campbell, Kate Merlin,

Robin Marks

Feedback received following evaluation of the Skin

Education Programs highlighted the need to set up

a web site that could provide information and

activities related to the programs. The aim of this

project is to develop an Internet site for the

Department that will be used to provide details of

our activities; information about diagnoses,

management and treatment of common skin

diseases; and linkage to related sites. The Skin

Education Programs will be a major component of

this Internet site. The first phase of the project

involved researching other web sites, including

dermatology web sites to view different contents,

styles and visual effects. Our target audience,

consisting of teachers and Maternal and Child

Health nurses were surveyed to find out what they

required from the web site. Consultation took

place with an education / IT expert and the web

site prototype was developed. The web site is due

to ‘go live’ at the beginning of 2003.

Date Commenced: June 2002

Progress of Project: To ‘Go Live’ early 2003

Funding Source: Skin and Cancer

Foundation of Victoria

Research Projects

Page 15: Department of Dermatology

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DATA COLLECTION SYSTEMS

The Standardised Dermatology Database

Project

Nicole Harman, Kate Merlin, Maria Moore,

Robin Marks

In 1995, a computerised Dermatology Data

Collection System was established in Victorian

public hospitals to collect demographic and

diagnostic data on patients attending dermatology

outpatient clinics. As the hospitals were using

different databases and data collection systems, a

new project was established to standardise data

collection system and develop a database that can

be implemented across the hospitals commenced.

Dermatologists and registrars at the hospitals

completed a survey of their requirements for a

standardised system, department heads were

interviewed to discuss positive and negative aspects

to their databases, and quality assurance audits

were conducted on the existing systems. Using the

information obtained from the interviews, surveys

and audits, a new standardised system was

developed and has been implemented at the

hospitals. The database is currently being

evaluated.

Date Commenced: May 2000

Progress of Project: Database being evaluated

and modified

Funding Source: Australian Dermatology

Research & Education

Foundation (ADREF),

Core budget

The SDD Quality Assurance Auditing

Nicole Harman, Maria Moore, Jan Campbell,

Katie O’Farrell, Jessica Chudwok (Health Information

Management students), Robin Marks

In 2001 it was found that the database contained

a large number of ‘Diagnosis pending’ codes that

had not been updated. An audit was conducted in

April 2002 to update ‘Diagnosis pending’ codes in

the database and investigate reasons why the

diagnoses had not been updated.

In 2002, the SDD was implemented into SVHM.

To evaluate the training sessions and identify how

accurately data was being entered into the SDD, a

series of 3 sequential audits of the database were

performed. This involved reviewing all the essential

information from the outpatient data entered into

the SDD from February to August 2002. It was

found that 26% of patients were not being

entered into the SDD. However, the data being

entered into the SDD, showed that the amount of

information being entered for each patient

increased over the audits, e.g. the percentage of

diagnostic details entered in audit 1 was 80.4%

and in audit 3 this had increased to 88.4%.

Ongoing education and training to the clinicians

each year is vital for the data collection system to

be accurate, reliable and valid.

Date Commenced: February 1995

Date Completed: Ongoing

Funding Source: Core budget

Page 16: Department of Dermatology

Database and Research Program –

Skin and Cancer Foundation

Nicole Harman, Jan Campbell, Rod Sinclair,

Peter Foley

This program aims to facilitate the collection and

analysis of data from the clinics at the Skin and

Cancer Foundation (Vic). To achieve this the Skin

and Cancer Foundation has subcontracted the

services of two staff members from the

Department of Dermatology for 3 days a week. As

from November 2002, Jan Campbell is working as

a Research Fellow and Nicole Jenner as the Clinical

Data Manager. The data collected has a number of

potential uses including epidemiology studies;

research projects; constructing continuing

education programs; teaching trainees; auditing

and quality assurance projects; and linking with

other clinical databases such as pathology.

Date Commenced: November 2002

Date Completed: ongoing

Progress of Project: SCF SDD data being

analysed; Questionnaires

are being developed.

Funding Source: Skin and Cancer

Foundation of Victoria

CLINICAL AND GENETIC RESEARCH

Familial alopecia areata

Jack Green, Rodney Sinclair

Alopecia areata is an autoimmune disorder of the

hair follicle that displays complex genetic

inheritance. On average, 20% of individuals with

alopecia areata have at least one other affected

relative. The purpose of this study was to survey

familial alopecia areata on the Australian continent.

Methods used to ascertain families included a mail

out to members of the alopecia areata support

association, the internet and from our hair clinics.

Probands were interviewed by phone or in person

and questionnaires were completed for each

pedigree. Subjects with an unclear diagnosis were

examined.

In 64 pedigrees, there were 169 affected family

members, equally divided between females (53%)

and males (47%). Other conditions frequently seen

in these pedigrees included thyroid disease (46%),

eczema (53%), asthma (46%), NIDDM (34%) and

psoriasis (27%). The results are consistent with

other reports of a majority of pedigrees having a

small number of affected members, of equal sex

distribution of alopecia areata and of association

with other immune disorders.

Date commenced: 1999

Date completed: 2001

Progress of Project: Presented at World

Congress of Dermatology,

2002

Funding source/s: Core budget

Research Projects

14

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15

Genetics of Alopecia areata

Shannon Harrison, Jack Green, Justine Ellis,

Steven Harrap, Rod Sinclair

Alopecia areata is a complex genetic disease which

most likely has several genes interacting with

environmental co-factors to cause disease. In the

initial part of the study an analysis was undertaken

in a single family with significant members over 3

generations. Linkage was assessed to candidate

gene areas on chromosome 21 and no significant

linkage was identified. Subsequently, an association

study in alopecia areata was undertaken in 15

individuals with alopecia areata to determine if

there was a genetic association between the

androgen receptor gene on the X chromosome.

A negative association was identified. This study is

ongoing and we are currently in the process of

collecting sib pairs as part of an international

collaborative effort with the aim being to

undertake a genome wide scan.

Date commenced: February, 1999

Progress of Project: Ongoing

Funding source/s: Scientific Research Fund of

the Australasian College of

Dermatologists: National

Alopecia Areata Foundation

of America

Clinical diagnostic criteria for Pili annulati

Jack Green, David de Berker, Rodney Sinclair

Pili annulati is rare hair shaft disorder that causes

banding of hairs. The alternating dark and light

bands which are more obvious in those with fair

hair are caused by cavities located in the cortex of

the hair shaft. Most reported cases have been

inherited in an autosomal dominant fashion where

there have been some sporadic examples. In three

families with this condition, we formally

investigated their clinical and transmitted light

microscopic findings. We found that most cases

are sub-clinical and that grade variability exists

between individuals and the number of hairs

affected and within the same individual in the

degree to which different hairs are affected. We

also found that the clinical banding pattern can be

lost after other insults to the hair cycle such as

alopecia areata of telogen gravidarn.

Date commenced: 2001

Date completed: 2001

Progress of Project: Published, Clinical and

Experimental Dermatology,

2002

Funding source/s: University of Melbourne

Collaborative Research

Fund

Genetics of pili annulati

Jack Green, Elizabeth Fitzpatrick, Sue Forrest, Justine

Ellis, Steven Harrap, Rod Sinclair

Pili annulati is thought to be a single gene disorder,

however, the pathogenesis of this condition is

unknown. We identified 3 large families with Pili

Annulati and undertook an investigation of the

genetics. After extracting DNA and excluding a

number of candidate gene loci, we undertook a

genome wide scan in a single family. Linkage has

been identified and we have excluded one

candidate gene in that area by mutation analysis.

We are currently in the process of undertaking

mutational analysis of all the candidate genes

within the target region.

Date commenced: 2000

Progress of Project: Ongoing

Funding source/s: Scientific Research Fund of

the Australasian College of

Dermatologists, Skin and

Cancer Foundation.

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16

Genetics of Marie Unna Hypotrichosis

Jack Green, Elizabeth Fitzpatrick, Sue Forrest,

Justine Ellis, Steven Harrap, Rod Sinclair

Marie Unna Hypotrichosis is a rare, inherited hair

disease that causes patterned hair loss and is also

associated with irregularities of the hair shaft. We

identified a large family who clinically appeared to

have Marie Unna Hypotrichosis. Marie Unna

Hypotrichosis has been linked to an area on

chromosome 8. Our investigation of the genetics in

this family failed to identify linkage to that area on

chromosome 8 and, in fact, any association was

excluded. We then proceeded to do a genome

wide scan and were able to identify linkage to an

area on another chromosome. We are planning to

perform mutational analysis of that region to try

and identify the causative mutation for this variant

of Marie Unna Hypotrichosis.

Date commenced: 2000

Progress of Project: Ongoing

Funding source/s: Scientific Research Fund of

the Australasian College of

Dermatologists, Skin and

Cancer Foundation.

Genetics of Papular Atrichia

Jack Green, Rod Sinclair, Abraham Zlotogorski,

Angela Christiano

Papular atrichia is a rare, inherited cause of

complete hair loss. A causative mutation was

identified in a Pakistani family in 1998. We had

previously seen an individual with this condition in

1991. Our patient had an apparent autosomal

dominant inheritance of this normally autosomal

recessive disorder. Genetic analysis was undertaken

of both the patient and his mother and it was

determined that his late father was a heterozygous

carrier of this condition. This is the first pseudo-

dominant case of papular atrichia.

Date commenced: 2001

Date completed: 2002

Progress of Project: Paper in the Journal of

Investigative Dermatology,

2002

Funding source/s: Scientific Research Fund of

the Australasian College of

Dermatologists.

De Novo Mutations in Monilethrix.

Horev L, Djabali K, Green J, Sinclair R, Martinez-Mir R,

Ingber A, Christiano AM, Zlotogorski A.

Mutations in the hair keratins hHb1 and hHb6 have

been recently reported to cause monilethrix, an

autosomal dominant hair shaft disorder

characterized by variable degrees of hair fragility

and follicular hyperkeratosis. We found 10 families

with monilethrix in which parents were not

clinically affected, and sequenced the hair keratin

hHb1, hHb3 and hHb6 genes in seven patients.

In five patients no mutations were found, while in

two patients we identified de novo mutations, at

the helix termination motif. We were unable to

identify any correlations between the phenotype

and the genotype in affected individuals.

Date commenced: 2001

Date completed: 2002

Progress of Project: Accepted for publication in

Experimental Dermatology

Funding source/s: Department o Dermatology,

Haddad Hospital, Jerusalem

Research Projects

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Loose anagen syndrome

Alvin Chong, Elizabeth Fitzpatrick, Sue Forrest,

Rodney Sinclair

Loose anagen syndrome is a rarely reported

disorder, mainly of childhood, where anagen hairs

a poorly anchored to the follicle and hence, easily

and painlessly extracted. The condition was first

described in 1984 and since then approximately 65

cases have been reported in the worldwide

literature. We identified 16 families with loose

anagen syndrome involving over 120 people and

undertook a study of the clinical aspects and

molecular genetics of the syndrome. We were able

to identify that there is variation in the phenotype

over time with marked fluctuations occurring in the

ease with which hair can be plucked. We also

determined that it is an autosomal dominant

disease with incomplete penetrance after having

clearly defined the clinical diagnostic criteria for

this condition

Date commenced: 1997

Date completed: 2001

Progress of Project: Thesis accepted for Master

of Medicine, University of

Melbourne

Funding source/s: University of Melbourne

Postgraduate Research

Scholarship

Androgenetic alopecia, prevalence and risk

factors: findings from an Australian study

Sinclair R, Severi G, Giles GG, English DR,

McCredie MRE, Hopper JL.

1,390 men were recruited at random from

electoral rolls to serve as controls in a case

controlled study of prostate cancer. All subjects

were interviewed in person and direct observations

of baldness were made. Men were grouped into

the falling baldness categories; no baldness, frontal

baldness, vertex baldness and full baldness. The

epidemiological data collected on these men was

used for analysis of risk factors for baldness using

unconditional logistic regression with androgenetic

alopecia as the response variable adjusted for age.

Further research is required to confirm the negative

association between lean body mass and the

completion of growth risk of androgenetic alopecia

later in life.

Date commenced: 2001

Date completed: 2002

Progress of Project: Submitted for publication

Funding source/s: NH&MRC, Tattersall’s and

Whitten Foundation.

Anti Cancer Council of

Victoria.

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A new clinical grading scale for female

androgenetic alopecia

Andrew Messenger, Rodney Sinclair

The pattern of hair loss seen with androgenetic

alopecia differs between men and women. In

women the frontal hairline seems to be preserved

and women may notice just a diffuse thinning over

the crown generally. The currently used grading

scale to assess female androgenetic alopecia is that

designed by Ludwig in the 1970’s. We developed

and validated a new clinical grading scale. Women

who presented with grades 1 or 2 hair loss were

found on histology to have androgenetic alopecia

in 60% of cases and chronic telogen effluvium in

40%. In contrast, women who presented with

stage 3, 4 and 5 hair loss had a 97% chance of

having androgenetic alopecia histologically. In the

final evaluation the terminal to vellus hair ratios

were correlated with clinical grade and a good and

linear correlation was recorded between the grade

of hair loss and the terminal to vellus hair ratio

seen histologically.

Date commenced: 2000

Date completed: 2002

Progress of Project: Being prepared for

publication

Funding source/s: Core budget, Monash

University Alfred Hospital

Histological Diagnosis of female androgenetic

alopecia

Rica Mallari, Damian Jolley, Jill Magee, David Whiting,

Stephen Kossard, Rodney Sinclair,

We undertook an investigation to evaluate the

reliability of a single horizontally sectioned scalp

biopsy in the diagnosis of female pattern hair loss.

207 women presenting with chronic diffuse hair

loss had three 4mm punch biopsies taken from

immediately adjacent skin on their mid scalp and all

3 biopsies were sectioned horizontally. The findings

were compared with 305 women who underwent

2 biopsies, with one being sectioned horizontally

and the other vertically. To correlate the histological

diagnosis with the clinical severity mid scalp, a

clinical grading scale was developed. We found

that application of the current diagnostic criteria

achieved accurate diagnostic definition in 98% of

women with triple horizontal biopsies versus 79%

with a single horizontal biopsy. 97% with a mid

scalp clinical grade of 3, 4 or 5 were diagnosed on

triple biopsy with female pattern hair loss. Scalp

biopsy for diagnosis should therefore be reserved

for women with a mid scalp clinical grade of 1 or 2.

Date commenced: 1999

Date completed: 2002

Progress of Project: Accepted for publication

Journal of the American

Academy of Dermatology.

Funding source/s: Core budget

Women Who Present With Female Pattern Hair

Loss Tend To Underestimate The Severity Of Their

Hair Loss

Seba Biondo Rodney Sinclair

Female pattern hair loss can be a source of

considerable distress for affected women. Our

hypothesis was that women with female pattern

hair loss who seek treatment would rate their

condition as more severe than the treating doctor.

We undertook this project to identify discrepancies

between the severity ratings of the women and the

clinicians. 30 women receiving treatment for biopsy

proven androgenetic alopecia and 44 women on

the waiting list to receive treatment for

androgenetic alopecia were recruited. Each

women completed a self report photographic

measure on the severity of their hair loss,

specifically developed for the study. No difference

was found between the severity ratings of the

women receiving treatment and their clinicians,

it was found that women in the waiting list group

Research Projects

Page 21: Department of Dermatology

19

underestimated the severity of their hair loss as

compared to their clinicians ratings. The results

indicate that women affected with androgenetic

alopecia who seek treatment for their hair loss do

not overestimate the severity of their hair loss, in

fact, they tend to underestimate it.

Date commenced: 2001

Date completed: 2002

Funding source/s: Department of Psychiatry,

Monash University

Community Prevalence of female androgenetic

alopecia

Desmond Gan, Rodney Sinclair

In this study questionnaires have been developed to

be sent out to a random sample of 6,000 people

aged above 18 sampled from the Australian

electoral roll in the city of Maryborough in central

Victoria. The questionnaire will be used to obtain

information about whether they or family members

have experienced baldness, dandruff, greying of

the hair or complications pertaining to baldness

(solar keratosis or skin cancer of the scalp). They

will be asked to self assess their hair thickness

using the scale provided. 500 respondents will be

invited for face to face hair and scalp examination

by a dermatologist and registrars recording the

degree of hair loss, greying of hair, and the

presence of dandruff.

Date commenced: Ongoing

Funding source/s: Core budget, Pharmacia

Quality of Life in Women with Female Pattern

Hair Loss and the Impact of Medical

Intervention

Seba Biondo Rodney Sinclair

Female pattern hair loss has recently become the

preferred term for female androgenetic alopecia, a

conditionproducing chronic progressive hair loss in

women. The morbidity related to the hair loss is

predominantly psychological. The purpose of this

study was to examine the impact of female pattern

hair loss on quality of life and the effect of

comprehensive medical assessment, explanation of

disease process and initiation of treatment by an

experienced dermatologis. 77 women with biopsy

proven female pattern hair loss receiving treatment

with oral anti-androgens, 53 women on a waiting

list to receive treatment for female pattern hair loss

and 82 women not affected by hair loss were

studied. Participants completed the women’s

female pattern hair loss quality of life

questionnaire. Findings confirmed the detrimental

impact of hair loss on the quality of life of affected

women and the lack of impact of medical

intervention on quality of life at 2 months. This

has significant implications for the treatment of

psychological difficulties associated with female

pattern hair loss and suggests a possible role for

adjunctive psychological intervention in the

management of this chronic dermatological

condition.

Date commenced: 2001

Date completed: 2002, Report completed

Funding source: Department of Psychiatry,

Monash University

Page 22: Department of Dermatology

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Genetics of Androgenetic Alopecia

Shannon Harrison, Justine Ellis, Steven Harrap,

Rod Sinclair

In recent years researchers at the Department of

Physiology at the University of Melbourne have

identified the genetic association between men

with androgenetic alopecia and polymorphisms on

the androgen receptor. There has been much

recent controversy about whether female pattern

hair loss is indeed the female corollary of male

androgenetic alopecia. There has been a revision of

terminology with female patterned hair loss

becoming the preferred term because of the

uncertainty about the nature of this association.

In order to determine whether female pattern hair

loss is genetically association with the same

polymorphisms on the androgen receptor seen in

male androgenetic alopecia, we undertook a study

of 150 women with clinical and histological

evidence of female pattern hair loss. Because

women have two X chromosomes of which by

lyonisation only one is active, the power required to

demonstrate an association is greater than that

required for the men. To date, DNA from over 100

women have been analysed and whilst a suggestive

association exists, further analysis is required to

achieve statistical significance.

Date commenced: 2001

Progress of Project: Ongoing

Funding source/s: Skin and Cancer

Foundation, Department of

Physiology, University of

Melbourne

Common Baldness, Dandruff and Greying of

Hair in Twins

Desmond Gan, Rodney Sinclair

Common baldness, seborrheoic dermatitis and hair

greying are thought to be under genetic control. In

order to investigate the nature of this genetic

association, we are developing a survey for

monozygotic and dyzogotic twins from the

Australian Twin Registry.

Date commenced: 2001

Progress of Project: Ongoing

Funding source/s: Core budget

Treatment of female androgenetic alopecia

with oral antiandrogens

Miriam Wewerinke, Rodney Sinclair

The prevalence of clinical hair loss in women

increases with age. Most data on the use of

androgen receptor antagonists pertain to their use

in women with hirsutes or acne. The role of

androgens in the management of women with

biopsy proven androgenetic alopecia, we studied in

100 women who received anti andorgenetic

treatment for more than 12 months. Pre- and

post-treatment photographs were assessed side by

side by three independent clinicians experienced in

the treatment of patients with hair loss and scored

using a visual analogue scale. The concordance

between examiners was assessed. Photographs

were rated as either improved, no change or worse.

Fewer than 10% of women were identified as

worse while on treatment and over 90% showed

either no change or improved. 30% had clearly

improved using the photographic documentation.

Date commenced: 1999

Date completed: 2001

Funding source/s: Core budget

Research Projects

Page 23: Department of Dermatology

21

Prevention of Hospital Acquired Pressure

Ulcers: a randomised controlled trial in the use

of a sheepskin underlay

Ken Montgomery, Damian Jolley, Rodney Sinclair

Pressure ulcers are a costly, burdensome and

prevalent complication to hospital stay. The

majority (up to 80%) have reported pressure ulcers

as stage 1 or stage 2, indicating damage to the

superficial layers of the skin. This type of injury is

often associated with combined forces of pressure,

moisture and friction and is potentially preventable

with the appropriate pressure reducing/relieving

support surface. Although many pressure relieving

support surfaces are available, there is little reliable

evidence to distinguish between them, on the basis

of either efficacy or cost effectiveness. This study

was a randomized trial that compared the

Australian Medical Sheepskin (AMS) to standard

hospital care in a large metropolitan teaching

hospital. The results suggest that the AMS can

provide effective reduction in the incidence of

pressure ulcers in low to moderate risk hospital

patients. Widespread use of the AMS has the

potential to substantially reduce patient discomfort,

hospital costs and possible litigation.

Date commenced: 1998

Date completed: 2002

Funding source/s: NH&MRC

CLINICAL TRIALS

A Phase III Multicentre, Double-Blind, Active-

Controlled, Parallel Study Comparing the

Efficacy and Safety of ZOVIRAX™ Cold Sore

Cream (Aciclovir 5% Cream) and Lidocaine 2%

to ZOVIRAX™ Cold Sore Cream Alone

Administered for 5 Days in Subjects with

Herpes Labialis Infection

Funding source: Glaxo- Wellcome

(Zovirax study ZOV30009/Parexel

No.22209)

Date Completed: March 5th, 2001

A double-blind, single-centre, placebo-

controlled clinical trial to examine the efficacy

and safety of DA-5018 cream as a treatment

for pruritus associated with mild/moderate

atopic eczema

Funding source: Stiefel (study CP S217-AUS-02)

Date Completed: April 29th, 2001

A multicenter, phase III, double blind study of

photodynamic therapy (PDT) with Metvix 160

mg/g cream in comparison to PDT with

placebo cream in patients with primary

nodular basal cell carcinoma

Funding source: Photocure (study PC T308/00)

Status: Ongoing

Multicenter, multinational, double-blind,

parallel, randomized, placebo controlled study

of leflunomide in the treatment of psoriatic

arthritis (PsA)

Funding source: Aventis (study HWA486/3L01)

Date Completed: July 15th 2002

Page 24: Department of Dermatology

22

A Multi-Centre, Double-Blind, Placebo-

Controlled Parallel Group Clinical Evaluation of

the Efficacy and Safety of 1.5% Ciclopirox

Olamine Body and Hair Shampoo in the Topical

Treatment of Tinea Versicolor (Pityriasis

Versicolor)

Funding source: (Stiefel study S227-AUS-03)

Status: Ongoing

Double Blinded Placebo controlled cross-over

study to investigate hydroxychloroquine and

acitretin in the treatment of cicatricial alopecia

Martin Wade, Keng Ee Thai, Shannon Harrison,

Edward Upjohn, Rod Sinclair

Date commenced: 1999

Status: Ongoing

Funding source/s: ADREF; Skin and Cancer

Foundation

Immiquimod studies

REFERENCE LIBRARY

A reference library is maintained on a bibliography

database using the computer software Endnote, in

order to catalogue all papers held within the

department. This database, which is continuing to

grow, now contains over 3,000 publications.

Research Projects

Page 25: Department of Dermatology

23

Publications 2001/2002

ARTICLES

2001

Marks R. Dermatoepidemiology, Wherefore art thou

in this perilous time of need? Int J Dermatol.

2001; 40: 167- 168.

Marks R, Gebauer K, Shumack S, Amies M, Bryden

J, Fox TL, Owens ML. Imiquimod 5% cream in the

treatment of superficial basal cell carcinoma,

Results of a multi-centre 6 week dose-response

trial. J Am Acad Dermatol. 2001; 44:807-813.

Marks R. (Guest Editor). Beyond the year 2000.

Clinics in Dermatol. 2001; 19, 1.

Lau PM, Marks R, Stewart K. The outcome of an

education program to assist pharmacists in

prescribing over-the-counter (OTC) products for

common skin diseases. Pharmacy Education. 2001;

1: 83-90.

Marks R, Foley PA, Sinclair RD. Dermatology.

Med J Aust. 2001; 176: 10.

Green A, Marks R. Invasive squamous cell

carcinoma of the skin, non-metastatic.

Clinical Evidence. 2001; 5: 1190-1195.

Plunkett A, Lau P, Stewart K, Marks R.

Skin conditions in the pharmacy, consumer

satisfaction and economic considerations.

Int J Pharm Practice. 2001; 9: 9-14.

Marks R. The public health approach to the burden

of common skin conditions in the community.

J Dermatol. 2001; 28: 602-5.

Marks R. Diagnosis in Dermatology - Tricks of the

trade. Aust Fam Phys. 2001; 30: 1028-32.

Foley P, Zuo Y, Plunkett A, Marks R. The frequency

of common skin conditions in preschool-age

children in Australia, 1. Atopic dermatitis. Arch.

Dermatol. 137; 293-300, 2001

Ng J, Foley, PA, Crouch RB, Baker CS. A case of

actinic prurigo successfully treated with

thalidomide. Australas. J. Dermatol. 42;

192-5, 2001

Thai KE, Young R, Sinclair R. Nail Apparatus

Melanoma. Aus J Dermatol. 2001; 42: 71-83.

Green J, Sinclair R. Perceptions of acne vulgaris in

final year medical student written examination

answers. Aus J Dermatol. 2001; 42:98-101.

De Berker D, Sinclair R. The Hair Shaft, normality,

abnormality and genetics. Clinics in Dermatol.

2001; 19:129-34.

Sinclair R, Dawber R. Androgenetic alopecia in

men and women. Clinics in Dermatol. 2001;

19:167-78.

Dawber R, Sinclair R. Hirsutes. Clinics in Dermatol.

2001; 19:187-99.

Sinclair R. Commentary. Clinics in Dermatol. 2001;

19:93-94.

Sinclair RD. Management of male pattern hair loss.

Cutis 2001; 68(1):35-40.

Curnow P, Sinclair R, Marks R. A public health

model for the prevention of cancer, the Australian

experience with melanoma and non melanoma skin

cancer’. Austral-Asian Journal of Cancer. 2001.

Thai KE, Sinclair R. Cutaneous Pili Migrans.

Br J Dermatol. 2001; 144:219.

Thai KE, Sinclair R. Spironolactone induced

Hepatitis. Aus J Dermatol. 2001; 42: 180-182.

Thai KE, Sinclair RD. Keratosis Pilaris and hereditary

koilonychia without monilethrix.

J Am Acad Dermatol. 2001; 45: 627-629.

Green J, Sinclair RD. Oral cyclosporin does not

arrest progression of androgenetic alopecia.

Br J Derm. 2001; 145:842-44.

2002

Marks R. The changing incidence and mortality of

melanoma in Australia. Recent Results in Cancer

Research. 2002; 160: 113-21.

Marks R, Foley P, Sinclair R. Updates in medicine,

Dermatology. Med. J. Australas. 176, 10, 2002

Page 26: Department of Dermatology

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Crouch R, Foley, P, Baker C. Actinic prurigo,

A retrospective analysis of 21 cases referred to an

Australian photobiology clinic. Australas. J.

Dermatol. 43: 128-32, 2002

Wade MS, Sinclair RD. Disorders of hair in infants

and children other than alopecia.

Clinics in Dermatology. 2002; 20:16-28.

Dolianitis C, Sinclair R. Optimal Treatment of Head

Lice, Is a No-Nit Policy Justified? Clinics in

Dermatology. 2002; 20: 94-95.

Sinclair R. Cryosurgery in dermatology, treatment

of malignant and premalignant skin disease.

Medical Cryology 2002; 2:149-170.

Zlotogorski A, Martinez-Mir A, Green J, Lamdagger

H, Panteleyevdagger AA, Sinclair R, Christiano AM.

Evidence for Pseudodominant Inheritance of

Atrichia with Papular Lesions. J Invest Dermatol.

2002;118:881-886.

Chong A, Sinclair R. Loose anagen syndrome,

A prospective study of three families.

Australas J Dermatol. 2002; 43:120-4.

Giles GG, Severi G, Sinclair R, English DR, McCredie

MRE, Johnson W, Hopper JL, Boyle P. Androgenetic

alopecia, acne and prostate cancer, findings from

an Australian case-control study. Cancer Epidemiol

Biomarkers Prev 2002; 11:549-53.

White PJ, Gray AC, Fogarty RD, Sinclair RD,

Werther GA, Wraight CJ. C-5 propyne-modified

antisence oligonucleotides penetrate the epidermis

in psoriatic and not normal human skin after topical

application. JID 2002;118:1003-1007.

Harrison S, Sinclair RD. Telogen Effluvium.

Clin Exp Dermatol. 2002;27:389-95

Harrison S, Sinclair RD. Telogen Effluvium. (German

Translation) Zeitscrift fur Hautkrankenheiten.

2002;75:389-95

Wade MS, Sinclair RD. Persistent depigmentated

regrowth following alopecia areata. J Am Acad

Dermatol 2002; 46: 619-20

Jenner N, Campbell J, Plunkett A, Marks R.

Cost of psoriasis: A study on the morbidity and

financial effects of having psoriasis in Australia.

Aust J Dermatol. 2002; 43: 255-61

Ciconte A, Mills A, Shipley A, Marks R. Subacute

cutaneous lupus erythematosus in six year old a

child, A report of a case and a review of the

literature. Austral J Dermatol. 2002, 43,62-4.

Marks R. The changing incidence and mortality of

melanoma in Australia. Recent Results in Cancer

Research. 2002; 160: 113-21.

Crouch RB, Foley, PA, Baker CS. The results of

photopatch testing 172 patients to sunscreening

agents at the photobiology clinic, St. Vincent’s

Hospital Melbourne. Australas. J. Dermatol.

43; 74: 2002

Crouch R, Foley, P, Baker C. Actinic prurigo,

A retrospective analysis of 21 cases referred to an

Australian photobiology clinic.

Australas. J. Dermatol. 43, 128-32, 2002

CASE REPORTS

Thai KE, Sinclair R. Cutaneous Pili Migrans.

Br J Dermatol. 2001; 144:219.

Thai KE, Sinclair R. Spironolactone induced

Hepatitis. Aus J Dermatol. 2001;42:180-182.

Thai KE, Sinclair RD. Keratosis Pilaris and hereditary

koilonychia without monilethrix.

J Am Acad Dermatol. 2001;45:627-629.

Green J, Sinclair RD. Oral cyclosporin does not

arrest progression of androgenetic alopecia.

Br J Derm. 2001;145:842-44.

Thai KE, Sinclair RD. Treatment of Bowen’s disease

of the penis with imiquoimod.

J Am Acad Dermatol 2002;46:470-1

Wade MS, Sinclair RD. Persistent depigmentated

regrowth following alopecia areata. J Am Acad

Dermatol 2002;46:619-20

Thai KE, Sinclair RD. Chronic telogen effluvium in a

man. J Am Acad Dermatol. 2002;47:605-7.

Publications 2001/2002

Page 27: Department of Dermatology

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Thai KE, Sheffield L, Forshaw K, Sinclair R, Herman

G, Pitt J, du Sart D. Somatic Mosaicism explains

the occurrence of X-linked dominant Conradi

Hunnerman Syndrome in an affected male.

Aus J Dermatol 2001, 42, A13.

Green J, de Berker D, Sinclair R. Marie Unna

Hereditary Hypotrichosis, First Australian Family.

Aus J Dermatol 2001, 42, A126

Green J, de Berker D, Sinclair R. Pili Annulati,

Characterization of the Phenotype. Aus J Dermatol

2001, 42, A126

Sinclair R, Howard A. Epidermoid carcinoma of the

nail apparatus treated with imiquomod 5% cream.

Aus J Dermatol 2002, 43, A6

ABSTRACTS AND LETTERS

Thai KE, Sheffield L, Forshaw K, Sinclair R, Herman

G, Pitt J, du Sart D. Somatic Mosaicism explains

the occurrence of X-linked dominant Conradi

Hunnerman Syndrome in an affected male.

Aus J Dermatol 2001;42:A13.

Green J, de Berker D, Sinclair R. Marie Unna

Hereditary Hypotrichosis: First Australian Family.

Aus J Dermatol 2001;42:A126

Green J, de Berker D, Sinclair R. Pili Annulati:

Characterization of the Phenotype. Aus J Dermatol

2001;42:A126

Sinclair R, Howard A. Epidermoid carcinoma of the

nail apparatus treated with imiquomod 5% cream.

Aus J Dermatol 2002;43:A6

Green J, Forrest S, Sinclair R. Familial alopecia

areata in Australia. Ann Dermatol Venereol. 2002;

129: 1S516.

Green J, Fitzpatrick E, Forrest S, Sincalir R.

A possible second locus for Programd patterned

alopecia. Aus J Dermatol 2002; 43:A25

Chong A, Fitzpatrick E, Forrest S, Sincalir R.

Clinical and Molecular genetics of loose anagen

syndrome: Results form a study of 16 families.

Aus J Dermatol 2002; 43:A17

Green J, Zlotogorski A, Martinez-Mir A, Lam HM,

Panteleyev A, Christiano A, Sinclair R Evidence of

pseudodominant inheritance of atrichia with

papular lesions. Aus J Dermatol 2002; 43:A31

Tosti A, Piraccini BM, Bergfeld WF, Camacho F,

Dawber RP, Happle R, Olsen EA, Price VH, Rebora

A, Shapiro J, Sinclair R, Vanneste D, Whiting

DA.Occupational alopecia or alopecia areata?

J Am Acad Dermatol. 2002 Oct;47(4):636-7.

NON-PEER REVIEW PUBLICATIONS

Thai KE, Sinclair R. Androgenetic Alopecia.

Medical Observer. 19 January 2001.

Thai KE, Sinclair R. Differential Diagnosis: alopecia

areata vs trichotillomania. Medical Observer.

2 February 2001.

Dolianitis C, Sinclair R. Management of Psoriasis.

Medical Observer. 25 May 2001.

BOOKS

Price C, Sinclair R. Fast Facts-Minor Surgery. Health

Press Limited. Oxford 2001.

Sinclair R, Marks R. A guide to the performance of

diagnostic procedures used in the management of

common skin diseases. St. Vincent’s Hospital

Department of Dermatology, Melbourne, 2002.

Sinclair R, Banfield C, Dawber R. Handbook of

diseases of the hair and scalp. (Italian Translation)

Blackwell Science, Oxford 2002

Campbell J, Foley P, Jenner N, Marks R, Merlin K,

Sinclair R, Welsh B. Skin - an education program for

Maternal & Child Health. Melbourne: Department

of Dermatology, St. Vincent’s Hospital Melbourne.

2002.

Merlin K, Campbell J, Witherow E, Jenner N, Foley

P, Marks R. Skin - an education program for Primary

Schools. Melbourne: Department of Dermatology,

St. Vincent’s Hospital Melbourne. 2002.

Page 28: Department of Dermatology

26

BOOK CHAPTERS

Wade M, Sinclair R. Hair abnormalities in women

and girls. In Parish LC, Brenner S, Ramos-e-Silva M.

Eds. Women’s Dermatology. From infancy to

maturity. Parthenon Publishing Group. New York

2001.

Korpan NN, Amaro JA, Gonsalves JCA, Monfrecola

G, Nordin P, Le Pivert PJM, Scalvenzi M, Sinclair R.

Cryosurgical dermatology. In Korpan NN. Ed. Atlas

of cryosurgery. Springer. Vienna. 2001.

Thai KE, Sinclair R. Androgenetic Alopecia.

In Lebwohl, Heymann, Berth-Jones Coulson. Ed.

Treatment of Dermatological Disease.Harcourt

Health Sciences. London. 2002.

Scarfe C, Sinclair R. Actinic Keratosis.

In Lebwohl, Heymann, Berth-Jones Coulson.

Ed.Treatment of Dermatological Disease. Harcourt

Health Sciences. London. 2002.

Marks R, Hill D. Prevention of Skin Cancer.

In, Sober AJ, Haluska FG, Eds. Skin Cancer.

The American Cancer Society Atlas Series.

Ontario,BC Decker Inc. 2001;325-339.

Hill D, White V, Marks R, Borland R. Changes in

sun-related attitudes and behaviours, and reduced

sunburn prevalence in a population at high risk of

melanoma. In, Public Health Communication,

Evidence for behavior change. Hornik RC Ed.

New Jersey,Lawrence Erlbaum Associates.

2001;163-178.

OTHER ACTIVITIES

The Department has been responsible for

innumerable public relations/ education activities

and resources such as comments in lay magazines,

radio and television interviews and patient

information leaflets and advice. These activities are

too numerous to specify.

Publications 2001/2002

Page 29: Department of Dermatology

27

Conferences

CONFERENCE PRESENTER

International Meetings - 2001

5th World Conference on Melanoma, Venice, Italy RM

American Academy of Dermatology Annual Meeting, RS

Washington DC

100th Meeting Japanese Dermatological Association, RM

Tokyo, Japan

Sixth Asia-Pacific Environmental and Occupational PF

Dermatology Symposium

The Eden IDEA Congress, Noordwijkerhout, Netherlands RM

8th World Congress on Cancer of the Skin Zurich, RM

Switzerland

International Society of Dermatology, Regional Meeting RM

Medical Education in Dermatology, Rhodes, Greece

New Zealand Dermatological Society and the PF, RS, CB, LMY

Australasian College of Dermatologists

Combined Meeting, Queenstown

European Academy of Dermatology and Venereology, Munich PF

6th Asian Dermatology Congress, Thailand RS

Australian Meetings 2001

The Australasian College of Dermatologists PF, RS, RM, JG

Annual Scientific Meeting, Adelaide

Australian Health Promotion Association Conference, KM

Gold Coast

International Meetings 2002

Global Transplant/Skin Cancer Collaborative Group Berlin, RM

Germany

Croatian Dermatovenerological Society of the Croatian RM

Medical Association, Optija, Croatia

Hellenic Dermatological Society, Scientific Meeting, RM

Athens, Greece

European Hair Research Society, Brussels RS, JG

World Congress of Dermatology, Paris RM, RS, CB, JG,PF

British Association of Dermatology, Edinburgh RS

CONFERENCE PRESENTER

International Meetings 2002 cont...

Annual Scientific Meeting, Wellington PF

11th Congress European Academy of Dermatology & RM

Venereology, Prague, Czech Republic

Koelmeyer Clinical Group, WHERE???? CB

Hair Forum 2002. Malayasian Society for Hair Science, RS

Kuala Lumpar

The Philippine League of Dermatologists 15th Regional RS

Conference of Dermatology, Manilla

Josef Plenck Lecture, Austrian Society for Dermatology RM

and Venereology, Vienna, Austria

Australian Meetings 2002

Maternal and Child Health Nurse Seminar, Melbourne PF

Cutaneous Biology and Endocrinology Workshop, Melbourne RS

The Australasian College of Dermatologists RM, NJ, PF,

Annual Scientific Meeting,Melbourne LMY,RS, JG

Maternal and Child Health Saturday RM, JC, KM, NJ

Conference, RMIT, Melbourne

12th Annual Scientific Meeting Australasian Health NJ, KM and

Research – Data Managers Association

(AHR-DMA), Brisbane.

The General Practitioner Conference and Exhibition, PF

Melbourne

Alopecia, Hair Today, Gone Tomorrow Cutaneous Biology RS

and Endocrinology Workshop, Melbourne

Page 30: Department of Dermatology

28

2001

International – Elective Students

Helen Bryden University of Glasgow

Sabine Seidl University of Munich

Carola Schmidt Ruprecht-Karls-Universitaet, Heidelberg, Germany

Jessica Nehrling University of Maryland, Baltimore, USA

International and Local Visitors to the Department

Dr Julie Cronk Dermatology resident, University of Minnesota, USA

Dr Mirjam Wewerinke Visiting doctor, University of Gronigen, Netherlands

Dr Roger Timms GP, James Paget Hospital, Great Yamouth, UK

Dr Behnaz Fazeli Visiting doctor, Elisabethinen Hospital, Linz, Austria

Dr Kirstin Charlesworth GP, Daylesford

2002

International – Elective Students

Elke Marksteiner University of Michigan, USA

Paul Foggit St. Bartholomew’s & The Royal London Hospital, UK

Katrina Barnett University of Maryland, USA

Lucy Schomberg St George’s Hospital, London, UK

Chantal Tomkins University of Nottingham, England

Eitan Amir University of Nottingham, Manchester, UK

International and Local - Visitors to the Department

Dr Sue Burge Clinical Dean,Oxford University School of Medicine, and Senior

Lecturer in Dermatology, The John Radcliffe, Oxford, England

Dr Veerle Verlinden Dermatology Registrar, University of Leuven, Belgium

Dr Andrew Messenger Senior Lecturer in Dermatology, Royal Hallamshire Hospital

Sheffield, UK

Prof Richard Scher Professor of Dermatology, University of Columbia New York, USA

Dr Kevin White Dermatology Resident, University of Pennsylvania, USA

Dr Stephen Richardson Lahey Clinic Dept, Internal Medicine, Burlington, MA, USA

Dr Jane Tam GP

Dr Zina Akhounova GP

Dr Jim McDonald GP

Visitors

Page 31: Department of Dermatology

29

The Skin and Cancer Foundation of Victoria maintains its close relationship with St. Vincent’s Hospital,

the University of Melbourne and Australasian College of Dermatologists in supporting the academic

Department at St. Vincent’s Hospital. This cooperative venture has been the envy of other medical

disciplines who are looking at ways of maintaining their service, teaching and research bases in a time

of economic rationalism when many of these components previously provided through the public

hospital system are being so constrained.

In service, the Department at St. Vincent’s Hospital has close links with the Skin and Cancer Foundation in many

aspects. This includes the dermatology registrar at St. Vincent’s undertaking biopsies and other minor

procedures on St. Vincent’s patients using the facilities at the Foundation. The St. Vincent’s registrar is able to

benefit from the supervision by plastic surgeons who attend the Foundation at the time of the procedure clinic.

Patients from St. Vincent’s are also referred across to the Foundation for phototherapy, for diagnostic purposes

in the contact dermatitis clinic, for hair and nail advice and management and to obtain the phototherapy

facilities which form such a large component of the clinical load at the Foundation these days.

The skin cancer assessment clinic has acted as a teaching and training resource for medical students as well as

the registrars from St. Vincent’s Hospital. Patients from this clinic have also been used in the teaching seminars

for 6th year medical students provided by the Foundation throughout the year.

The St. Vincent’s Department is frequently acting as an adviser to pharmaceutical companies on clinical trials of

new products. To undertake the clinical trials, the Department links with the Foundation as a central trials base.

This benefits both the Foundation and St. Vincent’s. Other research projects which have been shared between

St. Vincent’s and Skin and Cancer Foundation include the hair and nail research activities of Dr Rodney Sinclair.

The photography services of the Foundation have been a major contributor to the hair research. They have also

contributed in both the research and service in supporting the Department at St. Vincent’s Hospital. Other

technical resources at the Department have been supported by the Foundation such as the new internet site to

back up our public and professional education programs. The Foundation has provided a grant for this project

developed in the Department by Nicole Jenner.

As the Department has database expertise, a contractual arrangement has been commenced in which the

Department provides their expertise in developing and managing the Skin and Cancer Foundation patient

database. These databases, while strictly complying with the new privacy legislation, provide extremely

important research data which can be extracted and reported to enhance the clinical services provided by the

Foundation. The new occupational dermatology developments of Dr Rosemary Nixon have gone from strength

to strength since their establishment. Dr Nixon is an Honorary Senior Lecturer in Dermatology at the St.

Vincent’s Hospital Department, and the Department also assists with advice and guidance on directions and

research being undertaken by the new Centre. Dr Nixon has also been active in expanding the activities of the

Foundation to Monash University as well as the initial links with the University of Melbourne. In time, no

doubt, there will be sharing between University of Melbourne and Monash University medical students of the

teaching that is occurring at the Foundation.

The Foundation now has a very stable financial base, particularly with the development of the new Skin and

Cancer Foundation Pathology. This has allowed it to take both a short and long term view in its forward

planning and much of that has involved its relationship with the Department at St. Vincent’s Hospital. The

relationship is a strong one. It will continue to grow and we look forward to our future activities together.

Rod Sinclair

President

Skin & Cancer Foundation of Victoria

The Skin & Cancer Foundation of Victoria

Page 32: Department of Dermatology

30

The 20th World Congress of Dermatology in Paris, in June 2002, was

attended by 1,200 dermatologists. It was the largest gathering of

dermatologists ever seen in the world.

During the Congress, the Assembly of Delegates representing the member

societies of the International League of Dermatological Societies (ILDS) met to

discuss and decide future directions of the League. They elected a new board

for the ILDS (the International Committee of Dermatology) who then went on

to elect the President and Office bearers for the next five years. Professor

Robin Marks was elected the new President. Professor Georg Stingl from

Vienna was elected Secretary-General and Professor Ana Kaminsky from

Buenos Aires was elected the Treasurer. This is the first time an Australian has

ever held a position of this nature in international dermatology.

The ILDS has a number of other strategic directions, apart from running the

World Congress of Dermatology. These include the International Foundation

for Dermatology, the arm of the League dedicated to improving the outlook

for people affected by skin diseases in developing countries. The Foundation

runs a Regional Dermatology Training Centre in Moshi, Tanzania. Over 100

paramedical trainees have graduated after a two year course at the Centre.

They then return to organise dermatology practice or administration in their individual African states trying to

provide some level of dermatological service for those in need. A community-based project was undertaken in

Mali, West Africa, last year looking at four of the major common infestations/infections in Africa. Models of

care tested in this project may be applicable to other developing countries throughout the world.

The ILDS also acts as a global political body for dermatology, being the only non-government organisation in

dermatology in official relations with the World Health Organisation. It has contributed to the development of

the latest International Classification of Diseases list (ICD-10), as well as providing the section on dermatology in

the "Essential Drugs Handbook" of the WHO. Under the Derm-Link program, the League provides small grants

to dermatologists within the member societies in developing countries. These grants can provide items of

equipment for a dermatology department or support travel for training purposes.

One of the major new tasks, recommended by the Assembly of Delegates, is to look at and define the

boundaries of dermatology. We plan to develop and publish a document showing clearly what dermatology is

and what services dermatologists can provide. Individual member societies could use such a document within

their own country, with the imprimatur of the ILDS the global body for dermatology, to negotiate with

government and other organisations in these difficult times when dermatology seems to be being encroached

upon by so many people around us.

We have a marvellous International Committee of people who are widely experienced and very committed to

the League. There is no doubt that there is a lot to achieve. Keep your eye on this spot - over the next five

years there will be increased awareness of the activities of the League associated with steps forward in our aim

of improving access and care for people with diseases affecting their skin throughout the world.

Robin Marks

President

International League of Dermatological Societies

International League ofDermatological Societies

Page 33: Department of Dermatology

31

The Department of Dermatology at St. Vincent’s Hospital Melbourne, together with the Australasian

Hair and Wool Research Society, hosted the first Cutaneous Biology and Endocrinology Workshop at

the Mary Aikenhead Conference Centre, St. Vincent’s Hospital Melbourne in November 2002.

There were over 60 delegates, including dermatologists and basic scientists. Professor Chen Ming Chuong, a

developmental biologist from San Francisco and Dr Dennis Roop from the University of Baylor in Dallas, Texas

were the two international guest speakers. A variety of excellent scientific and clinical papers were delivered at

the meeting much of which, although arising within the context of hair research, had applications right

through cutaneous biology, particularly in the area of genetics research and gene therapy. A special part of the

meeting was a registrar training forum and clinical day held at the Skin and Cancer Foundation.

The meeting was an enormous success and no one who attended could fail to have been impressed by the

quality of scientific cutaneous research being conducted in Australia and New Zealand. The abstracts will be

published in full in Experimental Dermatology, the official journal of the Australasian Hair and Wool Research

Society.

Rod Sinclair

Conference Convenor

Cutaneous Biology andEndocrinology Workshop

November 8-10, 2002

Page 34: Department of Dermatology

32

Organisational Charts 2001-2002

Robin MarksProfessor of Dermatology

Senior Associates

Dr Abe DorevitchA/Prof Damien JolleyDr Harvey Rotstein

Dr Andrew MichaelidesDr Rosemary Nixon

Dr Chris BakerDirector of Clinical Services

Dr Peter FoleySenior Lecturer in Dermatology

Ms Jan CampbellDepartment Manager

Dr Rod SinclairSenior Lecturer in Dermatology

ConsultantDermatologists

Dr Peter FoleyDr Robert Kelly

Dr Chris Mc CormackDr Mei Tam

Dr Belinda Walsh

Dermatology Nurse

Ms Leoni Hill

Research Fellow

Dr Lee Mei Yap

Administrative Staff

Ms Marlene Rennie Administrative Officer

Mrs Helen GibsonAdministrative Officer

Registrars

Dr Cate ScarffResearch Registrar

Dr Suresh ChandraDr Laura Scardamaglia

Hospital Registrars(shared 6 monthly)

Research Staff

Ms Kate Merlin Programs Officer

Ms Nicole HarmanPrograms Officer

Ms Maria MoorePrograms Assistant P/T

Research Fellows

Ms Jack GreenDoctorate Student

Dr Martin WadeDoctorate Student

Dr Keng-Ee ThaiMasters Student

Robin MarksProfessor of Dermatology

Honorary Senior Associates

Dr Abe DorevitchA/Prof Damien JolleyDr Harvey Rotstein

Dr Andrew MichaelidesDr David Harman

Honorary Senior LecturerDr Rosemary Nixon

Dr Chris BakerDirector of Clinical Services

Dr Peter FoleySenior Lecturer in Dermatology

Ms Jan CampbellDepartment Manager

Dr Rod SinclairSenior Lecturer in Dermatology

ConsultantDermatologists

Dr Peter FoleyDr Robert Kelly

Dr Chris Mc CormackDr Mei Tam

Dr Belinda Walsh

Dermatology Nurse

Ms Leoni Hill

Administrative Staff

Ms Marlene Rennie Administrative Officer

Mrs Helen GibsonAdministrative Officer

Registrars

Dr Lee Mei YapResearch Registrar

Dr Paul CurnowDr Adriene Lee

Hospital Registrars(shared 6 monthly)

Research Staff

Ms Kate Merlin Programs Manager

Ms Nicole HarmanPrograms Manager

Ms Maria MoorePrograms Assistant P/T

Ms Liz WhitherowPrograms Assistant P/T

Visiting Fellows

Dr Susan BurgeDr Andrew Messenger

Research Fellow

Dr Stephen GilmoreMD student

Research Fellow

Dr Shannon Harrison

DEPARTMENT OF DERMATOLOGY 2001

DEPARTMENT OF DERMATOLOGY 2002

Page 35: Department of Dermatology

33

HEAD OF DEPARTMENT Robin Marks, AM, MBBS, MPH, FRACP, FACD

DEPARTMENT MANAGER Jan Campbell, BA (Hons), MA

ADMINISTRATIVE STAFF Marlene Rennie, Administrative Officer

Helen Gibson, Secretary/Administrative Assistant – Part Time

CLINICAL STAFF

Director of Clinical Dermatology Christopher Baker, MBBS, FACD

Visiting Consultant Dermatologists Peter Foley, MB, BS, B Med Sc, MD, FACD

Robert Kelly, MBBS, FACD

Christopher McCormack, MBBS FACD

Mei Tam, MBBS, FACD

Belinda Welsh, MBBS, MM, FACD

Andrew Michaelides, MBBS, MRCP, FACD

HOSPITAL REGISTRARS

2001 Suresh Chandra, MBBS

Laura Scardiamaglia, MBBS

2002 Adriene Lee, MBBS

Paul Curnow, MBBS

Dermatology Outpatient Department Leonie Hill, RN

RESEARCH STAFF

Senior Lecturers in Dermatology Rodney Sinclair, MBBS, FACD

Peter Foley, MBBS, B Med Sc, MD, FACD

Project Managers Kate Merlin, BMRA, GDipHSc (Hlth Prom & Hlth Ed), GCert IT

Nicole Harman, BMRA, Grad.Cert.HS (CDM)

Research Assistant Maria Moore, RN, BH

Research Registrars

2001 Cate Scarff, MBBS

2002 Lee Mei Yap, MBBS (Hons)

Bachelor of Medical Science Student

2002 Desmond Gan

Honorary Research Fellows

2001 Jack Green, MBBS RACGP

Keng-Ee Thai, MBBS BMed Sci

2002 Shannon Harrison, MBBS BMed Sci

Staff

Page 36: Department of Dermatology

34

The Department was established in 1995

with support from:

Victorian Faculty of the Australasian

College of Dermatologists

Skin & Cancer Foundation (Victoria)

St. Vincent’s Hospital (Melbourne) Ltd

The University of Melbourne

F & E Bauer Foundation

with corporate sponsorship from:

Commonwealth Serum Laboratories

Janssen-Cilag

Sandoz Australia

Ego Pharmaceuticals

Lederle Laboratories (Wyeth)

Schering-Plough

Galderma Australia

Roche Products

Stiefel Laboratories

List of Supporters

Without this support, the Department would not have been possible and we express our sincere

appreciation of these efforts and contributions from all those people and organisations

mentioned above.

The following external funding sources were used to assist research projects for 2001/2002

SOURCE PROJECT

The Jack Brokhoff Foundation Skin Education Project for Primary Schools

ANZ - Felton Bequest

The Ian Potter Foundation Skin Education Project for Maternal and

RE Ross Trust Child Health Centres

Gwendolyn Holly Bequest

The University of Melbourne for Loose Anagen Syndrome.

Postgraduate Research Scholarship.

Australasian College of Dermatologists Eczema Morbidity Study

Scientific Research Fund

F & E Bauer Foundation Psoriasis Qualitative Studies

Skin & Cancer Foundation of Victoria Development of the Website

William Joseph Payne Trust Digital camera for digital imaging of skin conditions

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