dental management of patients with toxic epidermal necrolysis: case reports

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PE-101 - DENTAL MANAGEMENT OF PATIENTS WITH TOXIC EPIDERMAL NECROLYSIS: CASE REPORTS. DAVI SILVA CARVALHO CURI, ANDRÉ LUCAS D ALMEIDA LYRIO DOS SANTOS, THAMIRES SILVA SOUZA, PATRÍCIA LEITE RIBEIRO LAMBERTI, ANTÔNIO FERNANDO PEREIRA FALCÃO, VINICIUS RABELO TORREGROSSA, VIVIANE ALMEIDA SARMENTO. FED- ERAL UNIVERSITY OF BAHIA. Rare and extremely serious, toxic epidermal necrolysis (TEN) usually comes as a hypersensitivity response to drug administration. Affecting more than 30% of the body surface, this disease has a high rate of morbidity and mortality. The oral mucosa is frequently affected, requiring participation of the sto- matologist on the multidisciplinary team that assists the patient. Two cases of patients with TEN were admitted to the intensive care unit of the Hospital of the Federal University of Bahia, Salvador, Bahia, Brazil. Woman, 22, had taken antibiotic, anti- inammatory, and analgesic treatment for 2 days and had disseminated erythematous rash that developed into painful blis- ters. Young woman, 17, came after a month of using an anti- convulsant treatment and had bullous lesions and diffuse painful sores on the lips and oral mucosa. The role of the dental team was presented and discussed. PE-102 - DENTAL TWINNING OF MAXILLARY CEN- TRAL INCISORS ASSOCIATED WITH AGENESIS OF THE HOMOLOGOUS TOOTH: CASE REPORT. CAROLINE FARIAS LEMOS, LUCIANA DUARTE CALDAS, BERNARDO FERREIRA BRASILEIRO, MARTA RABELLO PIVA, NAYANE CHAGAS CARVALHO. UNIVERSIDADE FEDERAL DE SERGIPE. Dental anomalies are common but very important alterations occurring in dental practice. Early detection of these anomalies can signicantly affect the prognosis of the affected teeth. Two examples are agenesis and twinning, which are characterized, respectively, by the congenital absence of a tooth germ and by two teeth attempting to develop from a single germ cell. Twinned teeth, often incisors, have a large bid clinical crown, a single root, and a single root canal. However, besides compromising aesthetics, given the presence of a diastema, these teeth cause mesiodistal discrepancies between the upper and lower teeth that cause dental malocclusion. Boy, 12, had twinning of teeth #11 and #21 plus agenesis of the homologous tooth. The occlusal changes generated by the presence of these abnormalities and the multidisciplinary treatment employed in this case are also described. PE-103 - DENTIGEROUS CYST INVOLVING MULTIPLE PERMANENT TEETH: REPORT OF AN UNUSUAL CASE. AMANDA LUCIO DO Ó SILVA, TONY SANTOS PEIXOTO, ROBERIA LÚCIA DE QUEIROZ FIGUEIREDO, JOZINETE VIEIRA PEREIRA, PATRÍCIA MEIRA BENTO, GUSTAVO PINA GODOY, CASSIANO FRANCISCO WEEGE NONAKA. UNIVERSIDADE ESTADUAL DA PARAÍBA. Dentigerous cyst (DC) is a developmental odontogenic cyst that encloses the crown of an unerupted tooth at the cementoenamel junction. DCs most often develop in associa- tion with mandibular third molars and maxillary canines. Involvement of multiple permanent teeth by DC is unusual, with only a few reported cases. Young woman, 13, was referred for evaluation of a painless swelling in the left maxilla. Intraoral examination disclosed persistence of decid- uous teeth #51, #52, and #53. Panoramic radiographs and computed tomography showed a large cystic lesion involving impacted permanent teeth #11, #12, and #13. Dentigerous cyst was provisionally diagnosed, prompting an incisional biopsy. Histopathological examination revealed a cystic cavity lined by thin, non-keratinized stratied squamous epithelium without rete ridges. The brous capsule exhibited hemorrhagic areas and discrete inammatory inltrate. A denitive diag- nosis of dentigerous cyst was made, and total enucleation of the lesion was performed. The patient remains under close follow-up. PE-104 - DENTINOGENESIS IMPERFECTA: FAMILY CASE. VIVIANE PALMEIRA DA SILVA, JULIANA ANDRADE CARDOSO, SUELLEN DA GUARDA, MARIA PALMA BARRETO, ARIANA GONÇALVES CARNEIRO, JENER GONÇALVES DE FARIAS. UNIME. Dentinogenesis imperfecta is considered a developmental genetic disorder of dentin that can occur with no systemic alteration. This autosomal-dominant disorder can be caused by mutations in the dentin sialophosphoprotein gene (DSPP). The diagnosis must be made carefully and with close atten- tion to detail because of the difculty differentiating it from other anomalies. Therefore the authors present a brief litera- ture review and report on the diagnostic method of a familys case of dentinogenesis imperfecta, discussing the clinical, radiographic, epidemiologic, and differential diagnostic vari- ables. PE-105 - DENTOFACIAL CHANGES OF NOONAN SYNDROME: REPORT OF TWO CLINICAL CASES. CAROLINE FARIAS LEMOS, LUCIANA DUARTE CALDAS, BERNARDO FERREIRA BRASILEIRO, NAYANE CHAGAS CARVALHO, MARTA RABELLO PIVA. UNIVERSIDADE FEDERAL DE SERGIPE. Noonan syndrome (NS) is a dominant autosomal genetic syndrome that affects both genders with an estimated incidence ranging from 1:1000 to 1:2500. It is an important differential diagnosis in patients with short stature, facial dismorphism, delayed puberty, and cryptorchidism. Among the facial changes typical of NS patients are ocular hypertelorism, eyelid ptosis, external palpebral ssure diverted downward, low im- plantation and incomplete rotation of the auricle, mandibular micrognathia, short and webbed neck, and a triangular-shaped face. Dental changes include maxillary atresia, which hinders proper tongue positioning, often causing posterior crossbite and occasionally anterior open bite. Moreover, because of mandibular micrognathia, these patients present with Angle Class II malocclusions. Two cases of SN patients are presented along with a description of their similarities in terms of den- tofacial changes and the therapeutic procedures adopted for each case. PE-106 - DERMOID CYST WITH EVOLUTION OF 30 YEARS IN SUBLINGUAL REGION: CASE REPORT. RAFAEL FERANDES DE ALMEIDA NERI, CAETANO GUILHERME CARVALHO PONTES, CLARISSE SAMARA ORAL AND MAXILLOFACIAL PATHOLOGY OOOO e152 Abstracts February 2014

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Page 1: Dental Management of Patients With Toxic Epidermal Necrolysis: Case Reports

ORAL AND MAXILLOFACIAL PATHOLOGY OOOO

e152 Abstracts February 2014

PE-101 - DENTAL MANAGEMENT OF PATIENTS WITHTOXIC EPIDERMAL NECROLYSIS: CASE REPORTS. DAVISILVA CARVALHO CURI, ANDRÉ LUCAS D ALMEIDALYRIO DOS SANTOS, THAMIRES SILVA SOUZA,PATRÍCIA LEITE RIBEIRO LAMBERTI, ANTÔNIOFERNANDO PEREIRA FALCÃO, VINICIUS RABELOTORREGROSSA, VIVIANE ALMEIDA SARMENTO. FED-ERAL UNIVERSITY OF BAHIA.

Rare and extremely serious, toxic epidermal necrolysis(TEN) usually comes as a hypersensitivity response to drugadministration. Affecting more than 30% of the body surface, thisdisease has a high rate of morbidity and mortality. The oralmucosa is frequently affected, requiring participation of the sto-matologist on the multidisciplinary team that assists the patient.Two cases of patients with TEN were admitted to the intensivecare unit of the Hospital of the Federal University of Bahia,Salvador, Bahia, Brazil. Woman, 22, had taken antibiotic, anti-inflammatory, and analgesic treatment for 2 days and haddisseminated erythematous rash that developed into painful blis-ters. Young woman, 17, came after a month of using an anti-convulsant treatment and had bullous lesions and diffuse painfulsores on the lips and oral mucosa. The role of the dental team waspresented and discussed.

PE-102 - DENTAL TWINNING OF MAXILLARY CEN-TRAL INCISORS ASSOCIATEDWITH AGENESIS OF THEHOMOLOGOUS TOOTH: CASE REPORT. CAROLINEFARIAS LEMOS, LUCIANA DUARTE CALDAS,BERNARDO FERREIRA BRASILEIRO, MARTA RABELLOPIVA, NAYANE CHAGAS CARVALHO. UNIVERSIDADEFEDERAL DE SERGIPE.

Dental anomalies are common but very important alterationsoccurring in dental practice. Early detection of these anomaliescan significantly affect the prognosis of the affected teeth. Twoexamples are agenesis and twinning, which are characterized,respectively, by the congenital absence of a tooth germ and bytwo teeth attempting to develop from a single germ cell. Twinnedteeth, often incisors, have a large bifid clinical crown, a singleroot, and a single root canal. However, besides compromisingaesthetics, given the presence of a diastema, these teeth causemesiodistal discrepancies between the upper and lower teeth thatcause dental malocclusion. Boy, 12, had twinning of teeth #11and #21 plus agenesis of the homologous tooth. The occlusalchanges generated by the presence of these abnormalities and themultidisciplinary treatment employed in this case are alsodescribed.

PE-103 - DENTIGEROUS CYST INVOLVING MULTIPLEPERMANENT TEETH: REPORT OF AN UNUSUALCASE. AMANDA LUCIO DO Ó SILVA, TONY SANTOSPEIXOTO, ROBERIA LÚCIA DE QUEIROZ FIGUEIREDO,JOZINETE VIEIRA PEREIRA, PATRÍCIA MEIRA BENTO,GUSTAVO PINA GODOY, CASSIANO FRANCISCOWEEGE NONAKA. UNIVERSIDADE ESTADUAL DAPARAÍBA.

Dentigerous cyst (DC) is a developmental odontogeniccyst that encloses the crown of an unerupted tooth at thecementoenamel junction. DCs most often develop in associa-tion with mandibular third molars and maxillary canines.Involvement of multiple permanent teeth by DC is unusual,

with only a few reported cases. Young woman, 13, wasreferred for evaluation of a painless swelling in the leftmaxilla. Intraoral examination disclosed persistence of decid-uous teeth #51, #52, and #53. Panoramic radiographs andcomputed tomography showed a large cystic lesion involvingimpacted permanent teeth #11, #12, and #13. Dentigerouscyst was provisionally diagnosed, prompting an incisionalbiopsy. Histopathological examination revealed a cystic cavitylined by thin, non-keratinized stratified squamous epitheliumwithout rete ridges. The fibrous capsule exhibited hemorrhagicareas and discrete inflammatory infiltrate. A definitive diag-nosis of dentigerous cyst was made, and total enucleation ofthe lesion was performed. The patient remains under closefollow-up.

PE-104 - DENTINOGENESIS IMPERFECTA: FAMILYCASE. VIVIANE PALMEIRA DA SILVA, JULIANAANDRADE CARDOSO, SUELLEN DA GUARDA, MARIAPALMA BARRETO, ARIANA GONÇALVES CARNEIRO,JENER GONÇALVES DE FARIAS. UNIME.

Dentinogenesis imperfecta is considered a developmentalgenetic disorder of dentin that can occur with no systemicalteration. This autosomal-dominant disorder can be causedby mutations in the dentin sialophosphoprotein gene (DSPP).The diagnosis must be made carefully and with close atten-tion to detail because of the difficulty differentiating it fromother anomalies. Therefore the authors present a brief litera-ture review and report on the diagnostic method of a family’scase of dentinogenesis imperfecta, discussing the clinical,radiographic, epidemiologic, and differential diagnostic vari-ables.

PE-105 - DENTOFACIAL CHANGES OF NOONANSYNDROME: REPORT OF TWO CLINICAL CASES.CAROLINE FARIAS LEMOS, LUCIANA DUARTE CALDAS,BERNARDO FERREIRA BRASILEIRO, NAYANE CHAGASCARVALHO, MARTA RABELLO PIVA. UNIVERSIDADEFEDERAL DE SERGIPE.

Noonan syndrome (NS) is a dominant autosomal geneticsyndrome that affects both genders with an estimated incidenceranging from 1:1000 to 1:2500. It is an important differentialdiagnosis in patients with short stature, facial dismorphism,delayed puberty, and cryptorchidism. Among the facialchanges typical of NS patients are ocular hypertelorism, eyelidptosis, external palpebral fissure diverted downward, low im-plantation and incomplete rotation of the auricle, mandibularmicrognathia, short and webbed neck, and a triangular-shapedface. Dental changes include maxillary atresia, which hindersproper tongue positioning, often causing posterior crossbiteand occasionally anterior open bite. Moreover, because ofmandibular micrognathia, these patients present with AngleClass II malocclusions. Two cases of SN patients are presentedalong with a description of their similarities in terms of den-tofacial changes and the therapeutic procedures adopted foreach case.

PE-106 - DERMOID CYST WITH EVOLUTION OF 30YEARS IN SUBLINGUAL REGION: CASE REPORT.RAFAEL FERANDES DE ALMEIDA NERI, CAETANOGUILHERME CARVALHO PONTES, CLARISSE SAMARA