PREMENOPAUSE

Menopause denotes the final menstrual bleeding.

The time closest to this event is called the peri- menopause, before that is the pre-menopause, and after it the post-menopause. The pre- menopause does not cover the whole of the womans life before the menopause, but merely the time (a) from around 40 years of age when a woman can reasonably be said to be approaching the menopause, or (when a woman feels the approach of the menopause, by experiencing pre -menopausal irregularities in her menstrual cycle or other `menopausal` or `climacteric` symptoms. The last few years of menstrual life are ussually years of varied patterns of short and long cycles; This perods of transition vary considerably in length, but usually to occupy about six to eight years before menopause. A PREMENOPAUSAL SYNDROME

The disruption of the ovulatory mechanism and the imbalance between progesterone and oestrogen establish a characteristic syndrome of premenopause. Such as sweating . a certain amount of hot flushes. D dizziness tingling sensation the in the extremities.headaches. sleeplessness. Worry and anxiety

Endometrial disease

The relative oestrogen dominance at premenopausal age is responsible for a higher than usual incidence of unscheduled bleeding The oestrogen`s stimulations without progesterone developes endometrial hyperplasia. and cotinous stimulation develope atypical hyperplasia and then endometrial carcinoma