ct dose estimation - iaea · the conversion factor is (1/59.1 =) 0.017 msv / (mgy.cm) included,...

61
John M. Boone, Ph.D., FAAPM, FSBI, FACR Professor and Vice Chair of Radiology University of California Davis Medical Center CT Dose Estimation

Upload: others

Post on 26-Feb-2021

1 views

Category:

Documents


0 download

TRANSCRIPT

Page 1: CT Dose Estimation - IAEA · The conversion factor is (1/59.1 =) 0.017 mSv / (mGy.cm) Included, data from 46 scanners, 21 single slice, 25 multislice Effective dose calculated with

1

John M. Boone, Ph.D., FAAPM, FSBI, FACR

Professor and Vice Chair of Radiology

University of California Davis Medical Center

CT Dose Estimation

Page 2: CT Dose Estimation - IAEA · The conversion factor is (1/59.1 =) 0.017 mSv / (mGy.cm) Included, data from 46 scanners, 21 single slice, 25 multislice Effective dose calculated with

2

Introduction

The CTDI Family of Metrics

Dose Length Product

Effective Dose

Dose Reporting

Summary

CT Dose Estimation

Page 3: CT Dose Estimation - IAEA · The conversion factor is (1/59.1 =) 0.017 mSv / (mGy.cm) Included, data from 46 scanners, 21 single slice, 25 multislice Effective dose calculated with

3

Introduction

Page 4: CT Dose Estimation - IAEA · The conversion factor is (1/59.1 =) 0.017 mSv / (mGy.cm) Included, data from 46 scanners, 21 single slice, 25 multislice Effective dose calculated with

4

Introduction

Page 5: CT Dose Estimation - IAEA · The conversion factor is (1/59.1 =) 0.017 mSv / (mGy.cm) Included, data from 46 scanners, 21 single slice, 25 multislice Effective dose calculated with

5

The radiation from CT has caught the eye of the public

Page 6: CT Dose Estimation - IAEA · The conversion factor is (1/59.1 =) 0.017 mSv / (mGy.cm) Included, data from 46 scanners, 21 single slice, 25 multislice Effective dose calculated with

6

California SB-1237, SB-58, AB-510

Dose reporting required as of July 1, 2012

Mad River Hospital

Cedars-Sinai

Alex Padilla

Page 7: CT Dose Estimation - IAEA · The conversion factor is (1/59.1 =) 0.017 mSv / (mGy.cm) Included, data from 46 scanners, 21 single slice, 25 multislice Effective dose calculated with

7

Introduction

The CTDI Family of Metrics

Dose Length Product

Effective Dose

Dose Reporting

Summary

CT Dose Estimation

Page 8: CT Dose Estimation - IAEA · The conversion factor is (1/59.1 =) 0.017 mSv / (mGy.cm) Included, data from 46 scanners, 21 single slice, 25 multislice Effective dose calculated with

8

CTDI:

Computed Tomography Dose Index

where it all began….

Tom Shope

Page 9: CT Dose Estimation - IAEA · The conversion factor is (1/59.1 =) 0.017 mSv / (mGy.cm) Included, data from 46 scanners, 21 single slice, 25 multislice Effective dose calculated with

9

CTDIL =

-L/2

+L/2

1

nT ∫ D(z) dz

100 mm

CTDI100 =

-50mm

+50mm

1

nT ∫ D(z) dz

Page 10: CT Dose Estimation - IAEA · The conversion factor is (1/59.1 =) 0.017 mSv / (mGy.cm) Included, data from 46 scanners, 21 single slice, 25 multislice Effective dose calculated with

10

Phantoms

100 mm long ion

chamber

CTDI: Measurement tools

Page 11: CT Dose Estimation - IAEA · The conversion factor is (1/59.1 =) 0.017 mSv / (mGy.cm) Included, data from 46 scanners, 21 single slice, 25 multislice Effective dose calculated with

11

32 cm body PMMA phantom

16 cm head PMMA phantom

also, pediatric body phantom

100 mm pencil chamber

PMMA plug

peripheral hole

center hole

Page 12: CT Dose Estimation - IAEA · The conversion factor is (1/59.1 =) 0.017 mSv / (mGy.cm) Included, data from 46 scanners, 21 single slice, 25 multislice Effective dose calculated with

12 Measuring CTDI100 in the real world

Page 13: CT Dose Estimation - IAEA · The conversion factor is (1/59.1 =) 0.017 mSv / (mGy.cm) Included, data from 46 scanners, 21 single slice, 25 multislice Effective dose calculated with

13

32.1 mGy

Page 14: CT Dose Estimation - IAEA · The conversion factor is (1/59.1 =) 0.017 mSv / (mGy.cm) Included, data from 46 scanners, 21 single slice, 25 multislice Effective dose calculated with

14

100 mm pencil chamber

and thin CT x-ray beam

100 mm CT x-ray beam

and small radiation meter

100 mm

Page 15: CT Dose Estimation - IAEA · The conversion factor is (1/59.1 =) 0.017 mSv / (mGy.cm) Included, data from 46 scanners, 21 single slice, 25 multislice Effective dose calculated with

15

center CTDI100 periphery CTDI100

Weighted CTDI:

CTDIw = ⅓ × CTDI100 + ⅔ × CTDI100

center periphery

Page 16: CT Dose Estimation - IAEA · The conversion factor is (1/59.1 =) 0.017 mSv / (mGy.cm) Included, data from 46 scanners, 21 single slice, 25 multislice Effective dose calculated with

16

helical CT acquisition

Page 17: CT Dose Estimation - IAEA · The conversion factor is (1/59.1 =) 0.017 mSv / (mGy.cm) Included, data from 46 scanners, 21 single slice, 25 multislice Effective dose calculated with

low pitch high pitch

Dose 1

pitch

Page 18: CT Dose Estimation - IAEA · The conversion factor is (1/59.1 =) 0.017 mSv / (mGy.cm) Included, data from 46 scanners, 21 single slice, 25 multislice Effective dose calculated with

18

Weighted CTDI:

Volume CTDI:

CTDIvol =

CTDIw

pitch

CTDIw = ⅓ × CTDI100 + ⅔ × CTDI100

center periphery

Page 19: CT Dose Estimation - IAEA · The conversion factor is (1/59.1 =) 0.017 mSv / (mGy.cm) Included, data from 46 scanners, 21 single slice, 25 multislice Effective dose calculated with

19

CTDIvol is a useful parameter

because it is required to be

displayable on all modern CT

scanners due to IEC

regulations. It is also stored in

the header of the CT images.

Siemens

General Electric

Page 20: CT Dose Estimation - IAEA · The conversion factor is (1/59.1 =) 0.017 mSv / (mGy.cm) Included, data from 46 scanners, 21 single slice, 25 multislice Effective dose calculated with

20

CTDI is a good measure of CT x-ray tube radiation output,

but is not a stand-alone metric for patient dose

etcetera….

Page 21: CT Dose Estimation - IAEA · The conversion factor is (1/59.1 =) 0.017 mSv / (mGy.cm) Included, data from 46 scanners, 21 single slice, 25 multislice Effective dose calculated with

r = 1.19

47”

119 cm waistline

28 cm

34”

86 cm waistline

32 cm

typical patient

CTDI body phantom

CTDI is a good measure of dose to

a 32 cm diameter, 1.19 g/cm3 piece

of plastic. Most patients will be

smaller, and have higher doses.

Larger patients will have lower

doses (at the same techniques)

Page 22: CT Dose Estimation - IAEA · The conversion factor is (1/59.1 =) 0.017 mSv / (mGy.cm) Included, data from 46 scanners, 21 single slice, 25 multislice Effective dose calculated with

AAPM Report 204

Page 23: CT Dose Estimation - IAEA · The conversion factor is (1/59.1 =) 0.017 mSv / (mGy.cm) Included, data from 46 scanners, 21 single slice, 25 multislice Effective dose calculated with

5.40 mGy = CTDIvol

(32 cm phantom)

water equivalent

diameter

circle of equal area

(weighted)

Page 24: CT Dose Estimation - IAEA · The conversion factor is (1/59.1 =) 0.017 mSv / (mGy.cm) Included, data from 46 scanners, 21 single slice, 25 multislice Effective dose calculated with

24

Size-specific dose estimate (SSDE)

To perform patient size-specific

dose estimation, the conversion

factor above is multiplied by the

value of CTDIvol.

Dosepatient CTDIvol × f

SSDE

Page 25: CT Dose Estimation - IAEA · The conversion factor is (1/59.1 =) 0.017 mSv / (mGy.cm) Included, data from 46 scanners, 21 single slice, 25 multislice Effective dose calculated with

5.40 mGy = CTDIvol (32 cm phantom)

SSDE = CTDIvol × f

13.0 mGy = 5.40 × 2.4

Page 26: CT Dose Estimation - IAEA · The conversion factor is (1/59.1 =) 0.017 mSv / (mGy.cm) Included, data from 46 scanners, 21 single slice, 25 multislice Effective dose calculated with

26

Introduction

The CTDI Family of Metrics

Dose Length Product

Effective Dose

Dose Reporting

Summary

CT Dose Estimation

Page 27: CT Dose Estimation - IAEA · The conversion factor is (1/59.1 =) 0.017 mSv / (mGy.cm) Included, data from 46 scanners, 21 single slice, 25 multislice Effective dose calculated with

27

L

Which scan has more “dose”?

L

…to first order, the dose is the same

D = De

Dm

Page 28: CT Dose Estimation - IAEA · The conversion factor is (1/59.1 =) 0.017 mSv / (mGy.cm) Included, data from 46 scanners, 21 single slice, 25 multislice Effective dose calculated with

28

L

DLP = CTDIvol × L (mGy • cm)

Dose Length Product (DLP):

DLP is related to the total energy deposited in the patient

Page 29: CT Dose Estimation - IAEA · The conversion factor is (1/59.1 =) 0.017 mSv / (mGy.cm) Included, data from 46 scanners, 21 single slice, 25 multislice Effective dose calculated with

a c

x-ray beam profile along z

Page 30: CT Dose Estimation - IAEA · The conversion factor is (1/59.1 =) 0.017 mSv / (mGy.cm) Included, data from 46 scanners, 21 single slice, 25 multislice Effective dose calculated with

f(z) DL(z)

L

b

-L/2 +L/2

Page 31: CT Dose Estimation - IAEA · The conversion factor is (1/59.1 =) 0.017 mSv / (mGy.cm) Included, data from 46 scanners, 21 single slice, 25 multislice Effective dose calculated with

DL(z) -L/2 +L/2

Page 32: CT Dose Estimation - IAEA · The conversion factor is (1/59.1 =) 0.017 mSv / (mGy.cm) Included, data from 46 scanners, 21 single slice, 25 multislice Effective dose calculated with

Dose profiles as a function of Scan Length

scan length DL(z

)

Page 33: CT Dose Estimation - IAEA · The conversion factor is (1/59.1 =) 0.017 mSv / (mGy.cm) Included, data from 46 scanners, 21 single slice, 25 multislice Effective dose calculated with

Equilibrium Dose as a function of Scan Length

Deq

D(L

)

Page 34: CT Dose Estimation - IAEA · The conversion factor is (1/59.1 =) 0.017 mSv / (mGy.cm) Included, data from 46 scanners, 21 single slice, 25 multislice Effective dose calculated with

TG-111 Method

Page 35: CT Dose Estimation - IAEA · The conversion factor is (1/59.1 =) 0.017 mSv / (mGy.cm) Included, data from 46 scanners, 21 single slice, 25 multislice Effective dose calculated with

TG-111 Method

Page 36: CT Dose Estimation - IAEA · The conversion factor is (1/59.1 =) 0.017 mSv / (mGy.cm) Included, data from 46 scanners, 21 single slice, 25 multislice Effective dose calculated with

TG-111 Method

Page 37: CT Dose Estimation - IAEA · The conversion factor is (1/59.1 =) 0.017 mSv / (mGy.cm) Included, data from 46 scanners, 21 single slice, 25 multislice Effective dose calculated with

L

Page 38: CT Dose Estimation - IAEA · The conversion factor is (1/59.1 =) 0.017 mSv / (mGy.cm) Included, data from 46 scanners, 21 single slice, 25 multislice Effective dose calculated with

AAP Task Group 200

& ICRU Phantom

Page 39: CT Dose Estimation - IAEA · The conversion factor is (1/59.1 =) 0.017 mSv / (mGy.cm) Included, data from 46 scanners, 21 single slice, 25 multislice Effective dose calculated with

39

ICRU Method: Real Time X-ray Meter

Page 40: CT Dose Estimation - IAEA · The conversion factor is (1/59.1 =) 0.017 mSv / (mGy.cm) Included, data from 46 scanners, 21 single slice, 25 multislice Effective dose calculated with

40 beam profile [ × RECT ]

Page 41: CT Dose Estimation - IAEA · The conversion factor is (1/59.1 =) 0.017 mSv / (mGy.cm) Included, data from 46 scanners, 21 single slice, 25 multislice Effective dose calculated with

41

Introduction

The CTDI Family of Metrics

Dose Length Product

Effective Dose

Dose Reporting

Summary

CT Dose Estimation

Page 42: CT Dose Estimation - IAEA · The conversion factor is (1/59.1 =) 0.017 mSv / (mGy.cm) Included, data from 46 scanners, 21 single slice, 25 multislice Effective dose calculated with

42

L

DLP = CTDIvol × L (mGy • cm)

Dose Length Product (DLP):

DLP is related to the total energy deposited in the patient

Page 43: CT Dose Estimation - IAEA · The conversion factor is (1/59.1 =) 0.017 mSv / (mGy.cm) Included, data from 46 scanners, 21 single slice, 25 multislice Effective dose calculated with

43

Most modern dosimetry is Monte Carlo based

=

person mathematical model

of person

Page 44: CT Dose Estimation - IAEA · The conversion factor is (1/59.1 =) 0.017 mSv / (mGy.cm) Included, data from 46 scanners, 21 single slice, 25 multislice Effective dose calculated with

44

CT geometry is modeled and organ doses are estimated

Page 45: CT Dose Estimation - IAEA · The conversion factor is (1/59.1 =) 0.017 mSv / (mGy.cm) Included, data from 46 scanners, 21 single slice, 25 multislice Effective dose calculated with

45

Gonads

Bone marrow

Colon

Lung

Stomach

Bladder

Breast

Liver

Esophagus

Thyroid

Skin

Bone surface

Brain

Salivary Glands

remainder

0.08

0.12

0.12

0.12

0.12

0.04

0.12

0.04

0.04

0.04

0.01

0.01

0.01

0.01

0.12

Organ dose wt E

Y

Y

Y

Y

Y

Y

Y

Y

Y

Y

Y

Y

Y

Y

Y

YY mSv

absorbed

effective dose

organ doses computed

tissue weighting factors from ICRP 103

× =

Page 46: CT Dose Estimation - IAEA · The conversion factor is (1/59.1 =) 0.017 mSv / (mGy.cm) Included, data from 46 scanners, 21 single slice, 25 multislice Effective dose calculated with

46

other minor details

equivalent dose effective dose

mSv mSv

absorbed dose

mGy

D D × wr = H H × wt = E

kerma

mGy

K

Page 47: CT Dose Estimation - IAEA · The conversion factor is (1/59.1 =) 0.017 mSv / (mGy.cm) Included, data from 46 scanners, 21 single slice, 25 multislice Effective dose calculated with

47

other minor details

equivalent dose effective dose

mSv mSv

absorbed dose

mGy

D D × wr = H H × wt = E

units

quantities

kerma

mGy

K

Page 48: CT Dose Estimation - IAEA · The conversion factor is (1/59.1 =) 0.017 mSv / (mGy.cm) Included, data from 46 scanners, 21 single slice, 25 multislice Effective dose calculated with

48

other minor details

CTDIvol is the air kerma

measured inside the phantom

equivalent dose effective dose

mSv mSv

absorbed dose

mGy

D D × wr = H H × wt = E

kerma

mGy

K

Page 49: CT Dose Estimation - IAEA · The conversion factor is (1/59.1 =) 0.017 mSv / (mGy.cm) Included, data from 46 scanners, 21 single slice, 25 multislice Effective dose calculated with

49

other minor details

Incident kerma leads to absorbed dose

estimate through the Monte Carlo process

equivalent dose effective dose

mSv mSv

absorbed dose

mGy

D D × wr = H H × wt = E

kerma

mGy

K

Page 50: CT Dose Estimation - IAEA · The conversion factor is (1/59.1 =) 0.017 mSv / (mGy.cm) Included, data from 46 scanners, 21 single slice, 25 multislice Effective dose calculated with

50

other minor details

correction for different types of radiation

such as a, b, n: wr for x-rays is 1.0

equivalent dose effective dose

mSv mSv

absorbed dose

mGy

D D × wr = H H × wt = E

kerma

mGy

K

Page 51: CT Dose Estimation - IAEA · The conversion factor is (1/59.1 =) 0.017 mSv / (mGy.cm) Included, data from 46 scanners, 21 single slice, 25 multislice Effective dose calculated with

51

other minor details

corrects for organ radiosensitivity using

tissue weighting factors, wt.

equivalent dose effective dose

mSv mSv

absorbed dose

mGy

D D × wr = H H × wt = E

kerma

mGy

K

Page 52: CT Dose Estimation - IAEA · The conversion factor is (1/59.1 =) 0.017 mSv / (mGy.cm) Included, data from 46 scanners, 21 single slice, 25 multislice Effective dose calculated with

abdomen

E = 0.015 × DLP

Effective dose (mSv) and dose length product (mGy.cm) for abdomen CT and the clinical

indication: rule out abscess.

The conversion factor is (1/59.1 =) 0.017 mSv / (mGy.cm)

Included, data from 46 scanners, 21 single slice, 25 multislice

Effective dose calculated with the ImPACT CT Dosimetry calculator

The short-cut calculation of E (abdomen)

Page 53: CT Dose Estimation - IAEA · The conversion factor is (1/59.1 =) 0.017 mSv / (mGy.cm) Included, data from 46 scanners, 21 single slice, 25 multislice Effective dose calculated with

53

Effective Dose per DLP

(AAPM TG-96)

Region of Body

Head and neck

Head

Neck

Chest

Abdomen / pelvis

trunk

k (mSv/[mGy-cm])

0.0031

0.0021

0.0059

0.014

0.015

0.015

DLP × k E

Page 54: CT Dose Estimation - IAEA · The conversion factor is (1/59.1 =) 0.017 mSv / (mGy.cm) Included, data from 46 scanners, 21 single slice, 25 multislice Effective dose calculated with

54

Introduction

The CTDI Family of Metrics

Dose Length Product

Effective Dose

Dose Reporting

Summary

CT Dose Estimation

Page 55: CT Dose Estimation - IAEA · The conversion factor is (1/59.1 =) 0.017 mSv / (mGy.cm) Included, data from 46 scanners, 21 single slice, 25 multislice Effective dose calculated with

55

WORKFLOW in RADIOLOGY

All images are digital (on PACS)

Radiologists look at images on computers

As they look at the images, they dictate their

“findings” using voice recognition software

In California, CTDIvol & DLP need to be included

into the Radiologist’s Report

Page 56: CT Dose Estimation - IAEA · The conversion factor is (1/59.1 =) 0.017 mSv / (mGy.cm) Included, data from 46 scanners, 21 single slice, 25 multislice Effective dose calculated with

EXAM DATE [5/24/2012 12:35 pm]

INDICATION:

[]

DOSE:

[Dose information for this CT examination:

Series 1: (no contrast)

CTDIvol = 12.4 mGy

DLP = 496 mGy-cm

Diameter = 28.2 cm

SSDE = 16.1 mGy

Series 2: (with contrast)

CTDIvol = 13.2 mGy

DLP = 577 mGy-cm

Diameter = 28.2 cm

SSDE = 17.2

UC Davis Health System CT scanners ……..low dose CT practice.]

FINDINGS:

[]

IMPRESSION:

[]

Report: Gaga, Lady – MRN: 1234567

text and

format setup

by institution

The Structured Dose Report with Radimetrics Feed:

Page 57: CT Dose Estimation - IAEA · The conversion factor is (1/59.1 =) 0.017 mSv / (mGy.cm) Included, data from 46 scanners, 21 single slice, 25 multislice Effective dose calculated with

57

Institutional CT dose assessment

UC DOSE: Dose Monioring Software

Page 58: CT Dose Estimation - IAEA · The conversion factor is (1/59.1 =) 0.017 mSv / (mGy.cm) Included, data from 46 scanners, 21 single slice, 25 multislice Effective dose calculated with

58

Introduction

The CTDI Family of Metrics

Dose Length Product

Effective Dose

Dose Reporting

Summary

CT Dose Estimation

Page 59: CT Dose Estimation - IAEA · The conversion factor is (1/59.1 =) 0.017 mSv / (mGy.cm) Included, data from 46 scanners, 21 single slice, 25 multislice Effective dose calculated with

CTDIvol: (mGy)

Is a measurement of “dose” to a large plastic phantom, and for

normal size patients CTDIvol underestimates their dose. Should

not be considered as the “patient dose”

Uses two reference phantoms, 16 cm and 32 cm, depending on

scan protocol. The 16 cm reference phantom is used for all

heads and for some pediatric bodies (depends on scanner)

DLP: (mGy cm)

Includes CTDIvol and scan length

Scales linearly with effective dose

Summary

Page 60: CT Dose Estimation - IAEA · The conversion factor is (1/59.1 =) 0.017 mSv / (mGy.cm) Included, data from 46 scanners, 21 single slice, 25 multislice Effective dose calculated with

60

Size Specific Dose Estimate (SSDE)

Is an automatic way in which to correct for patient

body size, to produce a more accurate dose

estimate.

Effective Dose (E)

Is not a physical dose metric, but rather embodies

organ radio-sensitivities

Is controversial to use for specific patients

Summary

Page 61: CT Dose Estimation - IAEA · The conversion factor is (1/59.1 =) 0.017 mSv / (mGy.cm) Included, data from 46 scanners, 21 single slice, 25 multislice Effective dose calculated with

61

Introduction

The CTDI Family of Metrics

Dose Length Product

Effective Dose

Dose Reporting

Summary

CT Dose Estimation