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Commission Meeting July 25, 2012

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Page 1: Commission Meeting July 25, 2012. Innovation Platform Program Fiscal Year 2012

Commission Meeting

July 25, 2012

Page 2: Commission Meeting July 25, 2012. Innovation Platform Program Fiscal Year 2012

Innovation Platform Program

Fiscal Year 2012

Page 3: Commission Meeting July 25, 2012. Innovation Platform Program Fiscal Year 2012

Purpose To link the development and innovation capabilities and capacities of an already established Innovation Platform and all its resources at an Ohio college or university or not-for-profit research institution to specific late stage development and innovation needs of Ohio companies

Innovation Platform – an already existing capacity that incorporates unique technology capabilities and strengths, talent, equipment, facilities, engaged industry partners, a track record of research commercialization and innovation, intellectual property, and other resources in a particular technology area that collectively can serve as a vehicle for significant, industry-defined and directed opportunities through the development and commercialization of new products and innovations

Page 4: Commission Meeting July 25, 2012. Innovation Platform Program Fiscal Year 2012

FY2012 Proposals• 37 proposals submitted

• 35 proposals passed Development’s administrative review

• Proposals based in one or more 8 technology areas:

- Advanced Materials (13) - Aeropropulsion Power Management (3)

- Fuel Cells & Energy Storage (7) - Medical Technology (14)

- Software Applications for business - Sensing & Automation Technologies (6)

and healthcare (3) - Solar Photovoltaics (3)

- Situational Awareness and

Surveillance Systems (3)

Page 5: Commission Meeting July 25, 2012. Innovation Platform Program Fiscal Year 2012

Program Basics

• Lead Applicants = Ohio colleges or universities or an Ohio not-for-profit public or private research institution. Proposals must include collaboration with at least two or more Ohio for-profit companies.

• Funding = $18 million available (FY12); Award range of $1 – $3 million

• External Evaluator = National Academies of Science (NAS)

Page 6: Commission Meeting July 25, 2012. Innovation Platform Program Fiscal Year 2012

Review of Proposals to Ohio’s Third Frontier Program, 2012-2013:

Innovation Platform Program (IPP) 2012

The National AcademiesJuly 25, 2012

Page 7: Commission Meeting July 25, 2012. Innovation Platform Program Fiscal Year 2012

7

The National Academies

• The National Academies bring together committees of experts in all areas of scientific and technological endeavors. These experts serve on a volunteer basis to address critical national issues.

• The National Research Council, which operates under the auspices of the National Academies, is committed to providing elected leaders, policy makers, and the public with expert advice based on sound scientific evidence.

Page 8: Commission Meeting July 25, 2012. Innovation Platform Program Fiscal Year 2012

8

Committee Membership

• Committee of 23 includes:

– Working engineers, scientists, academics, investors, and businessmen and women

– 3 are elected members of the National Academy of Engineering (NAE)

– 2 are elected members of the National Academy of Science (NAS) – 3 financial analysts– 5 Presidents or CEOs, 1 Vice President, and 1 Executive Director of

private (for profit) companies– Geographically diverse: members are from all over the United

States; – 17 previously served on NRC Committees to review proposals for

Ohio

Page 9: Commission Meeting July 25, 2012. Innovation Platform Program Fiscal Year 2012

9

IPP Evaluation CriteriaTechnical Merit & Plan• Can the technical challenges be

met?

• Are novel concepts, approaches or methods employed?

Commercialization Strategy• Does the team understand the total

resource requirements for achieving market entry?

• What is the specific value proposition of the proposed approach?

• Has the Innovation Platform already achieved at least proof of principle?

• How closely matched is the project with the existing or emerging supply chain’s capabilities?

Performance Goals• Will the project have an impact on

Ohio in three or more of the following areas?1) job creation2) personal wealth 3) new sales of products4) company creation or attraction5) follow-on investment 6) talent recruitment and 7) enhanced Ohio, national, and/or

international recognition

Experience and Qualifications• Is leadership demonstrated in all

critical phases of the proposal?

• Does the applicant team have the relevant experience to perform the work involved?

Page 10: Commission Meeting July 25, 2012. Innovation Platform Program Fiscal Year 2012

10

IPP Evaluation Criteria

Budget & Cost Share• Budget:

– Is the budget justified and adequate?

• Cost Share:– Is the cost share necessary and reasonable?– Does the cost share represent a specific new commitment, and is it in the form

of cash?– Is the cost share being used directly in support of the Innovation Platform?– Is the cost share firmly committed, with no contingencies or

conditions, from known sources and available to the Innovation Platform at the time of Proposal submittal?

• Does the proposal contain sufficiently detailed commitment letters, including an explanation of cost share commitment?

Page 11: Commission Meeting July 25, 2012. Innovation Platform Program Fiscal Year 2012

E Exceeds Requirements of the RFP

M Meets Requirements of the RFP

D Does Not Meet Requirements of the RFP

TMP Technical Merit and Plan

CS Commercialization Strategy

PG Performance Goals

EQ Experience and Qualifications

BCS Budget and Cost Share

Evaluation of Proposals

Page 12: Commission Meeting July 25, 2012. Innovation Platform Program Fiscal Year 2012

Rank

TMP

CS PG EQ BCSProposal (Applicant)

12-247Ophthalmic Imaging Center

(Cleveland Clinic Foundation)1 E E M E M

12-216

New Concept Devises Based on

Nanoscale Engineering of Polymer-

Liquid Crystal Interface

(K ent State University)

2 E E M E M

12-254

PET/MRI, a Next Generation Multi-

Modal Molecular Imaging Technology

Platform

(The Ohio State University)

3 E M E E M

12-204

Advanced Materials for Additive

Manufacturing Maturation (University

of Dayton)

4 E E M M M

12-258

The OH-Alive Innovator Platform: A

Process and Manufacturing Platform

for Cell Therapy

(Case Western Reserve University)

5 M M M E M

12-245

Products to Improve Orthopaedic

Patient Outcomes (PIOPO) (Cleveland

Clinic)

6 M M M E M12

Page 13: Commission Meeting July 25, 2012. Innovation Platform Program Fiscal Year 2012

13

TMP

CS PG EQ BCSProposal (Applicant)

12-208

Innovation Platform: Distributed Energy Storage

Systems

(The Ohio State University)

D D D D M

12-209

Situational Awareness Integration,

Visualization, Validation, Exploitation and

Demonstration (SAIVVED) Commercialization

Platform

(University of Dayton)

M D D E E

12-220

Commercialization of an Innovative

Neuromodulation and Neurostimulation

Technology Platform

(Case Western Reserve University)

E M M D M

12-233

Electrochemical Innovation Platform: Advanced

Materials for Energy Storage and Sensors

(Ohio University)

D D D D M

12-276Innovation Platform for Solar Photovoltaics

(University of Toledo)M D D M M

12-277

Ohio Sensor and Semiconductor Innovation

Platform

(The Ohio State University)

M D M M M

12-284

Ohio Platform for Tomorrow’s Industrial Medical

Imaging Systems and Equipment--OPTIMISE

(Case Western Reserve University)

D M M E M

Page 14: Commission Meeting July 25, 2012. Innovation Platform Program Fiscal Year 2012

RecommendedProposals

Page 15: Commission Meeting July 25, 2012. Innovation Platform Program Fiscal Year 2012

15

GoalSeeks to develop and commercialize new ophthalmologic

instrumentation, new surgical instruments, new contrast dyes, and automated software packages that will enhance high-resolution optical coherence tomography (OCT) systems.

Rank

TMP

CS PG EQ BCS

12-247Ophthalmic Imaging Center

(Cleveland Clinic Foundation)1 E E M E M

12-247Ophthalmic Imaging Center

(Cleveland Clinic Foundation)

Collaborators

OptoQuest $706k (Personnel) $613k (Personnel)

ImageIQ $520k (Services) $456k (Personnel, Services)

State Funds Cost Share

Strengths • Innovative• Highly Desired• Previous Success• Extensive leadership and

experience

Budget Requested Total

Budget$2,999,709

$6,489,271

40% to subcontracts

Page 16: Commission Meeting July 25, 2012. Innovation Platform Program Fiscal Year 2012

16

Market SizeDevice is aimed to become standard screening procedure for all corneal refractive

surgery and corneal stabilization therapy candidates. Currently, the vast majority of OCT imaging is performed on retinal patients. This

population represents approximately 2 million patients in the US that can receive an OCT exam up to 4 times a year. Opening OCT to the anterior segment market adds an additional 11 million cornea and refractive patients to the potential market for OCT

Other Economic Objectives:• 10 Technology licenses to Ohio-based companies.

• $5 M in licensing income based on Center-developed technologies

• Formation of 5 new companies

Rank

TMP

CS PG EQ BCS

12-247Ophthalmic Imaging Center

(Cleveland Clinic Foundation)1 E E M E M

12-247Ophthalmic Imaging Center

(Cleveland Clinic Foundation)

Year # of J obs Types Salary

3 43

5 unspecified

8 250

unspecified $75k+

Page 17: Commission Meeting July 25, 2012. Innovation Platform Program Fiscal Year 2012

17

GoalResolve existing technical issues of the polymer-liquid crystal interface, which in turn

will push core products to the next level of commercial success within 3 to 5 years to achieve a growth of more than 100 percent.

Rank

TMP

CS PG EQ BCS

12-216

New Concept Devises Based on

Nanoscale Engineering of Polymer-

Liquid Crystal Interface

(K ent State University) 2 E E M E M

12-216

New Concept Devises Based on

Nanoscale Engineering of Polymer-

Liquid Crystal Interface

(K ent State University)

Strengths • Clear Path to near term impact• Significant long-term potential• Collaborators will benefit from

essentially the same research without direct competition

Budget

Requested Total Budget

$3,000,000$6,000,000

70% to subcontracts

Collaborators

APS $250k (Personnel) $250k (Personnel)

AlphaMicron $800k (Personnel) $800k (Indirect)

Crystal Diag. $250k (Personnel) $250k (Personnel)

K ent Displays, Inc. $800k (Personnel, Supplies) $800k (Indirect, Personnel)

State Funds Cost Share

Page 18: Commission Meeting July 25, 2012. Innovation Platform Program Fiscal Year 2012

18

Market SizeTotal available markets for key KDI product lines are large. The writing tablet market is

projected to be $145M for 2014. Based on current customer pull and response, KDI expects 5% to 10% penetration in the accessible market for the HRSE Boogie Board RIP. Similarly AMI is expected to demonstrate a 30% increase in market over the next two years.

Other Economic Objectives:• $10M in follow-on investment• Continued Enhanced Recognition• $10M in new sales by 2013-2014

Rank

TMP

CS PG EQ BCS

12-216

New Concept Devises Based on

Nanoscale Engineering of Polymer-

Liquid Crystal Interface

(K ent State University) 2 E E M E M

12-216

New Concept Devises Based on

Nanoscale Engineering of Polymer-

Liquid Crystal Interface

(K ent State University)

Year # of J obs Types Salary

3 8 $45,000

5 unspecifiedunspecified

Page 19: Commission Meeting July 25, 2012. Innovation Platform Program Fiscal Year 2012

19

GoalBuild on the market introduction of integrated positron emission tomography

(PET)/magnetic resonance imaging (MRI) by Philips Cleveland to achieve rapid market growth and global adoption of PET/MRI-related products/services in the global healthcare community.

Rank

TMP

CS PG EQ BCS

12-254

PET/MRI, a Next Generation Multi-

Modal Molecular Imaging

Technology Platform

(The Ohio State University) 3 E M E E M

12-254

PET/MRI, a Next Generation Multi-

Modal Molecular Imaging

Technology Platform

(The Ohio State University)

Strengths • Well established capabilities and

capacities• PET/MRI system has superior imaging

quality relative to comparative systems

• Strong technical foundation • High potential for successful

commercialization

Budget

Requested Total Budget

$3,000,000 $6,026,690

5% to subcontracts

Collaborators

Philips $144k (Personnel) $2M (Personnel)

Cardinal Health $0 $5M(Research and

Production Facility)

State Funds Cost Share

Page 20: Commission Meeting July 25, 2012. Innovation Platform Program Fiscal Year 2012

20

Market Size

• Philips: the “within reach” market size will be at least $1 billion

• Cardinal: $2.3B by 2018

Other Economic Objectives:

• $46 M in new sales/revenue by 3 years, $113M by 5 years

• Attraction of 3 companies by 3 years, 10 by 8 years

• Follow-on investment of $13M by 3 years, $22M by 5 years

Rank

TMP

CS PG EQ BCS

12-254

PET/MRI, a Next Generation Multi-

Modal Molecular Imaging

Technology Platform

(The Ohio State University) 3 E M E E M

12-254

PET/MRI, a Next Generation Multi-

Modal Molecular Imaging

Technology Platform

(The Ohio State University)

Year # of J obs Types Salary3 525 74 unspecified $90,000

Page 21: Commission Meeting July 25, 2012. Innovation Platform Program Fiscal Year 2012

21

GoalThrough Additive Manufacturing, develop specific composites for applications

primarily directed at the aerospace industry in Ohio.

Rank

TMP

CS PG EQ BCS

12-204

Advanced Materials for Additive

Manufacturing Maturation

(University of Dayton) 4 E E M M M

12-204

Advanced Materials for Additive

Manufacturing Maturation

(University of Dayton)

Strengths • Cost-competitive and potentially

much lower in cost compared to conventional injection molding

• High level of interest from many potential industrial end-users

• Will have a substantial positive economic impact on the state of Ohio

Budget

Requested Total Budget

$2,999,050 $6,370,563

60% to subcontracts

Collaborators

Polyone $750k (Personnel, Services) $1.4M (Personnel, Supplies, Services)

RP+M $1M (Personnel, Supplies) $1M (Personnel, Other Direct)

Stratasys $0 $300k (Personnel)

GE Aviation $0 $100k (Personnel)

State Funds Cost Share

Page 22: Commission Meeting July 25, 2012. Innovation Platform Program Fiscal Year 2012

22

Market Size• The current market size is $1.3B and is expected to grow to $5B by

2020 as the production of end-use parts accelerates.

• The size of this market, inclusive of all energy storage technologies, has been anticipated by an earlier Frost & Sullivan report as growing at a 25% compounded rate to reach $6 Billion by 2020.

Other Economic Objectives:• $50M in sales after 5 years• $1M/ year in new sponsored research• Potential Expansion of RP+M into Dayton’s Aerospace Hub

Rank

TMP

CS PG EQ BCS

12-204

Advanced Materials for Additive

Manufacturing Maturation

(University of Dayton) 4 E E M M M

12-204

Advanced Materials for Additive

Manufacturing Maturation

(University of Dayton)

Year # of J obs Types Salary

3 26

5 83

Primarily

Manufacturing unspecified

Page 23: Commission Meeting July 25, 2012. Innovation Platform Program Fiscal Year 2012

23

GoalLeverage the existing capabilities of the Cellular Therapies Integrated Service, to

establish a facility that will support accelerated commercialization: from basic research to clinical trials and commercialization on an affordable, contract basis to researchers and biotechnology companies.

Rank

TMP

CS PG EQ BCS

12-258

The OH-Alive Innovator Platform:

A Process and Manufacturing

Platform for Cell Therapy

(Case Western Reserve University) 5 M M M E M

12-258

The OH-Alive Innovator Platform:

A Process and Manufacturing

Platform for Cell Therapy

(Case Western Reserve University)

Strengths • Will assist in developing protocols for

producing and releasing cellular therapy materials for clinical trials that meet FDA expectations

• Team has the potential to become a major contributor in the evolution of this technology and its commercialization

Budget

Requested Total Budget

$2,403,875 $4,807,751

20% to subcontracts

Collaborators

BioSpherix $0 $500k (Equipment)

BioOhio $30k (Personnel) $60k (Personnel)

Cleveland Clinic $83k (Personnel) $24k (Indirect)

Renovo $150k (Personnel) $294k (Services, Personnel)

Athersys $0 $100k (Personnel)

TECAN $0 $155k (Equipment, Personnel)

Nanofiber Solutions $211k (Supplies, Personnel) $481k (Supplies, Personnel)

State Funds Cost Share

Page 24: Commission Meeting July 25, 2012. Innovation Platform Program Fiscal Year 2012

24

Market Size• The Cell Therapy industry CTI alone (as opposed to regenerative medicine,

which includes small and large molecules, devices and cells) had global sales of $410 million in 2008, and is predicted to grow to $2.7 billion by 2012 and $5.1 billion by 2014

Other Economic Objectives:• $1M in new sales by end of year 5

• Formation of 4-6 new companies by year 5

• $4M in follow-on investment by year 5

Rank

TMP

CS PG EQ BCS

12-258

The OH-Alive Innovator Platform:

A Process and Manufacturing

Platform for Cell Therapy

(Case Western Reserve University) 5 M M M E M

12-258

The OH-Alive Innovator Platform:

A Process and Manufacturing

Platform for Cell Therapy

(Case Western Reserve University)

Year # of J obs Types Salary

3 8

5 14$82,000

Management &

Technicians

Page 25: Commission Meeting July 25, 2012. Innovation Platform Program Fiscal Year 2012

25

GoalDevelop software and other tools to improve surgical accuracy in total shoulder and hip

arthroplasty. This proposal includes the development of products designed to facilitate pre-surgical planning and improve accuracy of component placement during surgery

Rank

TMP

CS PG EQ BCS

12-245

Products to Improve Orthopaedic

Patient Outcomes (PIOPO)

(Cleveland Clinic) 6 M M M E M

12-245

Products to Improve Orthopaedic

Patient Outcomes (PIOPO)

(Cleveland Clinic)

Strengths • Significant progress already

made towards objectives

• Potential to reduce the cost of orthopaedic surgery and dramatically improve patient outcomes

• Reasonable and well-outlined technical plan and timeline

Budget

Requested Total Budget

$2,763,444 $5,564,019

50% to subcontracts

Collaborators

Custom Ortho. Solutions $600k (Personnel) $600k (Services)

Astro Manufacturing $450k (Personnel) $390k (Personnel)

ImageIQ $300k (Personnel) $300k (Personnel)

State Funds Cost Share

Page 26: Commission Meeting July 25, 2012. Innovation Platform Program Fiscal Year 2012

26

Market Size:

Other Economic Objectives:• $15M in new sales by year 3, $50M by year 5

Rank

TMP

CS PG EQ BCS

12-245

Products to Improve Orthopaedic

Patient Outcomes (PIOPO)

(Cleveland Clinic) 6 M M M E M

12-245

Products to Improve Orthopaedic

Patient Outcomes (PIOPO)

(Cleveland Clinic)

Product Size of Market Value of 1% capture

OrthoVis 24,000 US Orthopaedic Surgeons $1.2M/ year

RealBones 495,000 procedures $4M/year

IRIs 24,000 US Orthopaedic Surgeons $240k/year

Osteotomy PSIs 800,000 in 2011, 6.5% growth $4.8M/year

Year # of J obs Types Salary

3 35 $76,714

5 56 $78,839

4 Senior Management, 7 Managers,

16 Engineers, 37 manufacturing, 9

Sales/marketing, 2 Regulatory

experts, 4 Quality, 10 Admin,

2 Project Managers

Page 27: Commission Meeting July 25, 2012. Innovation Platform Program Fiscal Year 2012

27

Final Remarks

• Total state funds requested by the 6 proposals: $17,166,078

• The remaining 29 proposals, when ranked against the RFP’s criteria and requirements, scored significantly lower than the recommended 6

Thank You!The National Academies would like to thank the State of Ohio for placing its trust in our process and in our outstanding volunteer committee members.

Page 28: Commission Meeting July 25, 2012. Innovation Platform Program Fiscal Year 2012

QUESTIONS?

Page 29: Commission Meeting July 25, 2012. Innovation Platform Program Fiscal Year 2012

IntervieweesNot Recommended

Page 30: Commission Meeting July 25, 2012. Innovation Platform Program Fiscal Year 2012

30

GoalOSU-CAR is proposing to expand their platform to support a broader

penetration of Distributed Energy Storage Systems through deployment and demonstration of modular battery systems and associated power management and software integration products.

TMP

CS PG EQ BCSInnovation Platform: Distributed

Energy Storage Systems

(The Ohio State University)

12-208

D D D D M

Innovation Platform: Distributed

Energy Storage Systems

(The Ohio State University)

12-208

Collaborators State Funds Cost Share

RW Beckett Corp. $600k (Personnel) $1.7M (Personnel, Equipment)

BPL Global $400k (Personnel) $400k (Personnel, Equipment)

Strengths • Well thought-out technical

plan• Solid cost share

Budget Requested Total

Budget$2,750,000

$5,529,283

36% to subcontracts

Page 31: Commission Meeting July 25, 2012. Innovation Platform Program Fiscal Year 2012

31

Market Size• BPLG estimates the total market size to be $46, 303,359 in 2012 and

$130,407,516 in 2017. Estimated Revenues from BPL’s solution are $3,000,000 by 2017.

Other Economic Objectives• First year revenues: $1M; by 2016, revenues projected to be over $100M

Committee Concerns• Lead applicant lacks familiarity in industrial and distributed power generation

• automotive requirements are significantly different than utility and community-scale needs, and the proposal fails to make a convincing case that the team can handle the difference

• Proposal lacks specific commercialization and go-to-market strategies• Proposal does not sufficiently detail the value proposition of the products or

the present competition• Adoption of smart grid and community-scale systems likely to exceed the 3 to

5 year timeframe

TMP

CS PG EQ BCSInnovation Platform: Distributed

Energy Storage Systems

(The Ohio State University)

12-208

D D D D M

Innovation Platform: Distributed

Energy Storage Systems

(The Ohio State University)

12-208

Year # of J obs Types Salary

3 120

5 365$40,000 Primarily Manufacturing

Page 32: Commission Meeting July 25, 2012. Innovation Platform Program Fiscal Year 2012

32

GoalBuild on an existing capability to make available an open architecture hardware-in-the-

loop SA platform, where companies developing SA products can have their technologies evaluated, certified, and integrated into fully operational systems in order to increase consumer confidence and interest.

TMP

CS PG EQ BCSSituational Awareness Integration,

Visualization, Validation,

Exploitation and Demonstration

(SAIVVED) Commercialization

Platform (University of Dayton)

12-209

M D D E E

Situational Awareness Integration,

Visualization, Validation,

Exploitation and Demonstration

(SAIVVED) Commercialization

Platform (University of Dayton)

12-209

Collaborators State Funds Cost Share

Greenlight Optics $150k (Personnel) $75k (Personnel, Equipment)

PSS $800k (Personnel) $800k (Personnel)

Woolpert $800k (Personnel) $800k (Indirect, Personnel)

AFRL $0 $900k (Personnel)

City of Dayton $0 $1M (Personnel, Equipment)

DRA $0 $50k (Personnel)

Strengths • Builds on a strong set of

academic, industry, and Air Force assets

• Strong cost share

Budget Requested Total

Budget$2,763,444

$5,564,01960% to subcontracts

Page 33: Commission Meeting July 25, 2012. Innovation Platform Program Fiscal Year 2012

33

Market SizeAir Traffic Control (ATC) equipment market: projected to reach $3.9 billion by

the year 2017.The UAV electro-optical/infrared sensors system market will grow from $813

million in fiscal year 2011 to nearly $1.7 billion in fiscal year 2020.Bio- and chemical sensors market is expected to experience high growth to

be worth $13 billion by the end of 2011, and estimates suggest it will reach $21 billion by 2016.

Other Economic Objectives• Over $4M/year in new sales in 3 years, nearly $9M in 5 years• Around $4M in follow-on investment in 5 years

Committee Concerns• No discussion of UAV regulations or other issues associated with urban

deployment of UAV’s• Serious risk of failure for non-technical, non-commercial reasons (public

reaction) , and economic impacts will require customers--other cities--to overcome public resistance to deployment

• It is not clear in the proposal that the Air Force technology and data to be used in this system would remain accessible in a commercialization venture, as opposed to a military deployment

TMP

CS PG EQ BCSSituational Awareness Integration,

Visualization, Validation,

Exploitation and Demonstration

(SAIVVED) Commercialization

Platform (University of Dayton)

12-209

M D D E E

Situational Awareness Integration,

Visualization, Validation,

Exploitation and Demonstration

(SAIVVED) Commercialization

Platform (University of Dayton)

12-209

Year # of J obs Types Salary

3 31

5 69$65,000 unspecified

Page 34: Commission Meeting July 25, 2012. Innovation Platform Program Fiscal Year 2012

34

GoalDevelop and conduct commercialization clinical trials to support FDA approval and

marketing of two Neuromodulation /Neurostimulation devices based on the existing platform. One application will restore hand and arm functions to patients with upper extremity paralysis due to spinal cord injury or stroke. The other application will provide relief of phantom limb pain in post amputation patients.

TMP

CS PG EQ BCSCommercialization of an Innovative

Neuromodulation and Neurostimulation

Technology Platform

(Case Western Reserve University)

12-220

E M M D M

Commercialization of an Innovative

Neuromodulation and Neurostimulation

Technology Platform

(Case Western Reserve University)

12-220

Collaborators State Funds Cost Share

NDI Medical $2.3M (Personnel) $356k (Supplies, Services)

SPR Therapeutics $400k (Personnel, Indirect) $170k (Services)

Strengths • Novel and well-planned

technical approach• Clear solution to unmet

medical needs

Budget Requested Total

Budget$2,763,444

$5,564,019

90% to subcontracts

Page 35: Commission Meeting July 25, 2012. Innovation Platform Program Fiscal Year 2012

35

Market Size• Restoration of Upper Extremity Motor Function: 265k patients with spinal cord

injury; proposal estimates revenue of $6M during the first year on the market, growing to $24M by the third year of sales.

• Treatment of Chronic Pain following Limb Amputation: 1.7M patients with amputated limbs, 95% with chronic pain, proposal estimates revenue of $28M during the first year on the market, increasing to $70M during the second year on the market.

Other Economic Objectives• Revenue/year by year 3: $6M, in year 5: $24M• $5M in sponsored follow-on research in the next 5 years

Committee Concerns• Proposal fails to disclose the receipt of and performance resulting from several

related prior OTF awards

TMP

CS PG EQ BCSCommercialization of an Innovative

Neuromodulation and Neurostimulation

Technology Platform

(Case Western Reserve University)

12-220

E M M D M

Commercialization of an Innovative

Neuromodulation and Neurostimulation

Technology Platform

(Case Western Reserve University)

12-220

Year # of J obs Types Salary

3 25Mgmt &

Engineering$100,000+

5 95 Manufacturing $50,000

Page 36: Commission Meeting July 25, 2012. Innovation Platform Program Fiscal Year 2012

36

GoalOhio University proposes to use its Electrochemical Innovation Platform to transition

two technologies to commercial products: (1) a metal recycling process for used battery cathodes to recover metals for use in new lithium ion batteries (in collaboration with BASF Corporation), and (2) develop a low-cost, high-accuracy urea sensor for diesel emission control; (in collaboration with E3 Clean Technologies)

TMP

CS PG EQ BCSElectrochemical Innovation Platform:

Advanced Materials for Energy Storage

and Sensors

(Ohio University)

12-233

D D D D M

Electrochemical Innovation Platform:

Advanced Materials for Energy Storage

and Sensors

(Ohio University)

12-233

Collaborators State Funds Cost Share

E3 Clean Technologies $400k (Services, Personnel) $400k (Services, Personnel)

BASF $0 $700k (Personnel, Equipment)

Strengths • Metal recycling could significantly

reduce the cost of materials used in lithium-ion battery cathodes

• BASF and Ohio University are highly qualified and experienced

Budget

Requested Total Budget

$2,763,444 $5,564,019

17% to subcontracts

Page 37: Commission Meeting July 25, 2012. Innovation Platform Program Fiscal Year 2012

37

Market SizeMetal Recycling :

• Consumer electronics market size: $5 to $10B per year. The cathode is 50% of the cost of the battery cell; hence, cathodes occupy ~$1B per year of the consumer electronics battery market. Additionally, Decreasing the cost of the cathode would result in a $2 to $3B market opportunity for cathode materials in the automotive market.

Urea Sensor :• Today, the market size is approximately 700,000 units per year. This is

expected to grow to 2,000,000 units by 2016. At $30/sensor, this translates to a $60M market.

Other Economic Objectives• Over $100M in new product sales by year 5• New jobs pay nearly double the local prevailing wage

Committee Concerns• Projects are essentially separate, result: untenable management plan• No OEM’s are presently onboard with the commercialization plan of the UREA

sensor• Insufficient details supplied on the metals recycling process and alternate

pathways

TMP

CS PG EQ BCSElectrochemical Innovation Platform:

Advanced Materials for Energy Storage

and Sensors

(Ohio University)

12-233

D D D D M

Electrochemical Innovation Platform:

Advanced Materials for Energy Storage

and Sensors

(Ohio University)

12-233

Year # of J obs Types Salary

3 95*

5 225 $70,000 unspecified

Page 38: Commission Meeting July 25, 2012. Innovation Platform Program Fiscal Year 2012

38

GoalTo establish an Innovation Platform for Solar Photovoltaics (IPSPV) at the University of

Toledo, which will support the near-term commercialization goals of four Ohio-based companies. In each case, the collaborators have a product that requires additional PV research in order to accelerate market entry and sales growth

TMP

CS PG EQ BCS

12-276

Innovation Platform for Solar

Photovoltaics

(University of Toledo) M D D M M

12-276

Innovation Platform for Solar

Photovoltaics

(University of Toledo)

Collaborators State Funds Cost Share

Willard & K elsey $375k (Personnel, Services) $375k (Personnel, Services)

Solar Spectrum $375k (Personnel, Services) $377k (Personnel, Services)

Xunlight $375k (Personnel) $375k (Personnel)

Isofoton $375k (Personnel) $375k (Personnel)

Strengths • Technical tasks are

achievable• Team has extensive

experience

Budget Requested Total

Budget$2,763,444

$5,564,019

50% to subcontracts

Page 39: Commission Meeting July 25, 2012. Innovation Platform Program Fiscal Year 2012

39

Market Size• W&K: The US electricity market was $400B in 2009. Costs of electricity are going

up at rate of ~7% per year, accelerating the time to grid parity cross over for PV. The US Electricity market had ~1000 GW of capacity in 2006.

• Isofoton: the HCPV market is currently ~0.5% of the worldwide PV Market. The PV market has grown at about 40% year on year for last 15 years with 26 GW installed in 2011. So the size of the market in 2001 was roughly 120 MW. Isofoton expects the HCPV market will grow at about 40%/yr., which translates to a size of 168 MW in 2012, 235 in 2013, 329 in 2014, 461 in 2015, 646 in 2016

Other Economic Objectives• Over $135M in total revenue by year 3, over $300M in year 5• Other details listed as trade secrets

Committee Concerns• Questionable past performance on OTF awards by WK• Recent layoffs and decision to re-tool operations at WK raise serious worries

regarding succesful completion of the project• Overall solar market may not be receptive to the new products described in

the proposal

TMP

CS PG EQ BCS

12-276

Innovation Platform for Solar

Photovoltaics

(University of Toledo) M D D M M

12-276

Innovation Platform for Solar

Photovoltaics

(University of Toledo)

Year # of J obs Types Salary

3 300 ********** *********

5 700 ********** *********

Page 40: Commission Meeting July 25, 2012. Innovation Platform Program Fiscal Year 2012

40

GoalThe team will characterize, grow, pattern, and otherwise process compound

semiconductor samples and give advice and recommendations regarding the design of a proposed cryogenic electro-optic probe station. Two of the projects—the development of new infrared-detector arrays and the growth of bulk gallium nitride (GaN)—clearly advance the state of the art and can be accomplished in the 3-year timeframe.

TMP

CS PG EQ BCS

12-277

Ohio Sensor and Semiconductor

Innovation Platform

(The Ohio State University) M D M M M

12-277

Ohio Sensor and Semiconductor

Innovation Platform

(The Ohio State University)

Collaborators State Funds Cost Share

Momentive $340k (Personnel) $525k (Indirect)

LakeShore Cryotronics $330k (Personnel, Supplies) $330k (Personnel, Supplies)

L-3 Communications $0 $1.2M (Personnel, ******)

Strengths • The project makes good use of

the different strengths and capabilities of the participants

• Extensive experience with semiconductor device materials

Budget Requested Total

Budget$2,763,444

$5,564,019

26% to subcontracts

Page 41: Commission Meeting July 25, 2012. Innovation Platform Program Fiscal Year 2012

41

Market Size• CE: For IRTAS there is ~$20M/year market size for the next 3-4 years. For

Microcam, ~$20M/year in sales are anticipated for the next 3-4 years.

• Momentive: world-wide, possibly over $400M by late 2013

• Lake Shore: A recent 2010 report on the IR imaging market says it expects that the overall thermal market will be more than 1.1 million units in 2016 ($3.4 B in value).

Other Economic Objectives• Revenues from new products: at least $66M/year by year 5• Become an international center of semiconductor-based sensor technologies

Committee Concerns• Commercialization strategy is flawed: using the supplied numbers, it is

impossible for the 4″ GaN wafer project to show a profit in the foreseeable future.

• Distinct impression that the project is designed more to provide opportunities for NWL than to create jobs or economic impact in Ohio

• General lack of overlap between the MPM project and the rest of the group

TMP

CS PG EQ BCS

12-277

Ohio Sensor and Semiconductor

Innovation Platform

(The Ohio State University) M D M M M

12-277

Ohio Sensor and Semiconductor

Innovation Platform

(The Ohio State University)

Year # of J obs Types Salary

3 47*

5 51$51,000+

Manufacturing

& Engineers

Page 42: Commission Meeting July 25, 2012. Innovation Platform Program Fiscal Year 2012

42

GoalsCollaborating with OEMS, this proposal will leverage CWRU’s expertise to assist companies with

development and commercialization of new products: (1) with QED, to develop new radiofrequency (RF) breast-coil-biopsy-plate systems dedicated to the

significant reduction of false positives and false negatives in breast cancer diagnostics; (2) with Philips Medical Systems, Inc., to develop RF spine coils for both excitation and detection of

proton signals for ultra-high-field scanners; and (3) with Hyper Tech Research, Inc., to develop MgB2 designs of magnetic resonance imaging (MRI)

systems utilizing higher-temperature superconducting main magnets in order to reduce the need for liquid helium.

TMP

CS PG EQ BCS

12-284

Ohio Platform for Tomorrow’s

Industrial Medical Imaging Systems

and Equipment--OPTIMISE

(Case Western Reserve University)D M M E M

12-284

Ohio Platform for Tomorrow’s

Industrial Medical Imaging Systems

and Equipment--OPTIMISE

(Case Western Reserve University)

Collaborators State Funds Cost Share

QED $700k (Personnel, Supplies) $990k (Personnel, Machinery)

Philips $684k (Personnel, Services) $864k (Personnel)

Hypertech $720k (Supplies, Services) $1M (Personnel, Supplies)

Strengths • OPTIMISE’s industrial

partners include all five leading OEM’s

• Excellent experience in the field

Budget Requested Total

Budget$2,763,444

$5,564,019

70% to subcontracts

Page 43: Commission Meeting July 25, 2012. Innovation Platform Program Fiscal Year 2012

43

Market Size• QED: total world potential market for the products can be estimated at $45M by

2015• Philips: The current annual market remains flat at around 6 or 7 systems per year.

Growth will come however as 7T demonstrates diagnostic advantage relative to 3T and achieves regulatory clearance

• HT: Overall market for magnets in this space will be approximately $250 million in the U.S.

Other Economic Objectives• Over $20M in revenues/year by year 5• General expectation of Benefits to Personal Wealth, Follow-on Investment,

Recruitment of Talent and Enhanced Global Recognition

Committee Concerns• The proposal does not convincingly detail an established platform for the

intended projects

TMP

CS PG EQ BCS

12-284

Ohio Platform for Tomorrow’s

Industrial Medical Imaging Systems

and Equipment--OPTIMISE

(Case Western Reserve University)D M M E M

12-284

Ohio Platform for Tomorrow’s

Industrial Medical Imaging Systems

and Equipment--OPTIMISE

(Case Western Reserve University)

Year # of J obs Types Salary

3 26

5 83

$50k+ for manuf.,

$75k+ for others

Manufacturing

& Engineers

Page 44: Commission Meeting July 25, 2012. Innovation Platform Program Fiscal Year 2012

44

Committee Membership

• Committee members were recruited based on technical expertise as well as experience with business practices, technology transfer, venture capital, and economic development.

• Bias and Conflict of Interest– Potential members reviewed full list of participating institutions and

collaborators before nomination

– After nomination, each member completed bias and conflict forms which were reviewed by NRC staff and discussed by the committee

Page 45: Commission Meeting July 25, 2012. Innovation Platform Program Fiscal Year 2012

45

T. S. Sudarshan, ChairCEO and President, Materials

Modification, Inc.

Viola L. AcoffHead and Professor, Dept. of

Metallurgical and Materials Engineering, Univ. of Alabama

Catherine G. AmbroseAssociate Professor of

Orthopaedic Surgery, Univ. of Texas

David E. Aspnes (NAS)Distinguished University

Professor, Dept. of Physics, North Carolina State Univ.

Carol CherkisLife Sciences Industry

Consultant, NewCap Partners

David E. Crow (NAE)Senior VP, Pratt and Whitney (ret) and professor emeritus of

mechanical engineering at the Univ. of Connecticut

Paul A. EricksonAssociate Professor, Mechanical and Aerospace Engineering, UC Davis

Bruce GitterSenior principle scientist and manager of nuclear

medicine imaging, Covance Laboratories, Inc.

Jahan K. JewayniIndependent Wealth Management Consultant

Matt JonesPartner, Nth Power

Mohammad A. KarimVice President for ResearchOld Dominion University

Chester KolodziejExecutive Director, Freedom Field Renewable Energy, Inc

Committee Membership

Page 46: Commission Meeting July 25, 2012. Innovation Platform Program Fiscal Year 2012

46

Laura MazzolaVice President of Global Health Products, Wave 80 Biosciences

Trent MolterAssociate Research Professor and Business Development Officer, Center for Clean Energy

Engineering, Univ. of Connecticut

C. Bradley Moore (NAS)Professor of Chemistry Emeritus at Univ. of California, Berkeley

Nabil NasrDirector, Center for Integrated Manufacturing Studies, Rochester Institute of Technology

Arthur L. PattersonPresident and CEO, CMC, LLC

Shalini PrasadProfessor of bioengineering at Univ. of Texas, Dallas

Lloyd M. Robeson (NAE)Professor of Materials Science and Engineering, Lehigh Univ. and Principle Research Associate, Air Products and Chemicals (ret)

Subhash C. Singhal (NAE)Independent Consultant and Battelle Fellow Emeritus, Pacific Northwest National Laboratory

Norman A. WereleyProfessor and Associate Chair of Aerospace Engineering, Univ. of Maryland

Jim WheelerSenior Vice President of Economic Competitiveness Policy and Research, Thomas P. Miller and Associates

Raul E. ZavaletaCEO, Indigo BioSystems, Inc.

Committee Membership

Page 47: Commission Meeting July 25, 2012. Innovation Platform Program Fiscal Year 2012

47

Committee ProcessFirst meeting: April 19-20, 2012• ODOD Presentation on IPP

• Extensive discussion on all proposals

• Through consensus, selected 13 proposals for future interviews

Between meetings, committee members continued in-depth evaluation of the 13 interviewees, including examination of their financial and technical viability

Second meeting: May 30-June 1, 2012• Held 13 interviews

• Each 50 minute session was conducted in true “interview” format

• After Interviews, held a final dialogue with ODOD staff:– Prior performance of interviewees on prior OTF grants– Requirements and objectives of the IPP

• Through consensus, committee determined which proposals best satisfied the

requirements of the RFP and their respective rank-order