CLETE ANTHONY KUSHIDA, M.D., PH.D., RST, RPSGT

CONTACT INFORMATION

Stanford Sleep Medicine Center 450 Broadway Street, MC 5704 Pavilion C, 2nd Floor Redwood City, CA 94063-5704 650-721-7560, Fax 650-721-3465, E-mail clete@stanford.edu

EDUCATION

1994-1996 Stanford University, CA June 1996 NIH Fellowship, Sleep Medicine 1991-1994 University of California, San Diego June 1994 Residency, Neurology 1990-1991 Queen's Medical Center, HI June 1991 Internship, Internal Medicine 1982-1990 Pritzker School of Medicine M.D. June 1990 Medicine University of Chicago, IL Ph.D. August 1986 Biopsychology* 1981-1982 Stanford University, CA M.S. June 1982 Biological Sciences 1977-1981 Stanford University, CA B.A.S. June 1981 Biological Sciences and Psychology

Diplomate, American Board of Sleep Medicine, April 1996 Registered Polysomnographic Technologist (RPSGT), Board of Registered Polysomnographic

Technologists, June 1, 1998 Registered Sleep Technologist (RST), American Board of Sleep Medicine, October 25, 2011

*Thesis: “The physiological, biochemical, and behavioral effects of chronic paradoxical sleep deprivation in the rat”

CLINICAL PRIVILEGES

1997- Stanford University Hospital and Clinics, Stanford, California 1996-2002 California Pacific Medical Center, San Francisco, California

HONORS AND AWARDS

2014 2013 PROSE (The American Publishers Awards for Professional and Scholarly Excellence) Award winner for Multivolume Reference in Science (The Encyclopedia of Sleep) from the Association of American Publishers

2013 Nathaniel Kleitman Distinguished Service Award, American Academy of Sleep Medicine 2012-2013 Stanford Advanced Leadership Development Program 2009 2009 Visiting Professor, Scripps Memorial Hospital, La Jolla, CA 2008-2009 Stanford Leadership Development Program 2008 2008 Visiting Lecturer, University of Pittsburgh Medical Center, Pittsburgh, PA 2006 Fellow, American Academy of Sleep Medicine 2005 Helmut S. Schmidt Award, American Board of Sleep Medicine Service Award 1999 1999 Kershman Memorial Lecturer, Eastern Association of Electroencephalographers 1996 Finalist and Honorable Mention, American Sleep Disorder Association's Young Investigator

Award 1996 Associated Professional Sleep Societies Trainee Travel Fellowship, Sleep Research Society 1995 Finalist, American Sleep Disorder Association's Young Investigator Award 1995 Associated Professional Sleep Societies Trainee Travel Fellowship, Sleep Research Society 1990 Smith-Kline Research Prize, JABSOM Annual Biomedical Sciences Symposium 1988 Highest Honors, Physical Diagnosis, University of Chicago Pritzker School of Medicine 1987 Kraft Nutrition Fellowship: Metabolic effects of REM sleep deprivation in rats, University of

Chicago Pritzker School of Medicine 1987 NIH Summer Research Award, University of Chicago Pritzker School of Medicine 1986 Medical Student Summer Research Award, University of Chicago Pritzker School of Medicine 1985 Joseph Kelly Memorial Award for Excellence in Graduate Studies, University of Chicago 1983-1984 National Research Service Award, University of Chicago

Clete A. Kushida, M.D., Ph.D., RPSGT 2

1981 Departmental Honors in Psychology, Stanford University

PROFESSIONAL APPOINTMENTS

2010- Professor, Psychiatry and Behavioral Sciences, Stanford University Medical Center Evaluating sleep disorders in patients, conducting clinical research, and teaching clinical fellows, students, and other physicians

2010-curr Medical Director, Stanford Sleep Medicine Center, Stanford University Supervising sleep medicine clinical services 2008-2010 Acting Medical Director, Stanford Sleep Medicine Center, Stanford University Supervising sleep medicine clinical services 2007-2009 Adjunct Associate Professor, Sleep Medicine, Touro University, Nevada Courtesy appointment 2004-2010 Associate Professor, Psychiatry and Behavioral Sciences, Stanford University Medical

Center 2001-2004 Assistant Professor, Psychiatry and Behavioral Sciences, Stanford University Medical

Center 2001-2005 Assistant Clinical Professor, Neurosciences, University of California, San Diego School

of Medicine Courtesy appointment 1996-curr Director, Stanford Center for Human Sleep Research, Stanford University Supervising research at a 5-bed facility equipped for extended studies on sleep and circadian

rhythms 1996-2001 Staff Physician and Clinical Instructor, Stanford Sleep Disorders Clinic, Stanford

University

RESEARCH AND CLINICAL EXPERIENCE

1994-curr Stanford Sleep Medicine Center, Division of Sleep Medicine, Stanford University Evaluating sleep disorders in patients, conducting clinical research on the neurocognitive and

cardiovascular effects of obstructive sleep apnea, the prediction and risk factor assessment of sleep-related breathing disorders, the appraisal of novel pharmacologic treatments of insomnia and restless legs syndrome, and the evaluation of countermeasures for sleep loss

1992-1994 Sleep Research Laboratory, University of California, San Diego Conducted basic research on the expression of muscarinic receptor mRNA in rat brain with

REM sleep deprivation using in-situ hybridization histochemistry in Dr. J. Christian Gillin's laboratory

1992-1994 Sleep Disorders Clinic, VA Medical Center and University of California, San Diego Evaluated patients with sleep disorders with Dr. Sonia Ancoli-Israel 1987-1988 Brain Tumor Information Service, Chicago, Illinois Obtained medical histories from patients on the nation's first brain tumor hotline 1982-1990 Sleep Research Laboratory and Department of Vascular Surgery, University of Chicago Conducted basic research on the physiologic and biochemical effects of chronic REM sleep

deprivation in rats with Drs. Allan Rechtschaffen and Bruce L. Gewertz as research advisors 1980-1981 Stanford Center for Education and Research, Stanford University Designed and constructed an apparatus that presented 1 msec flashes of simple patterns to

subjects while screening for changes in visual evoked responses 1979-1982 Stanford Sleep Research Laboratory, Stanford University Conducted basic research on the EEG correlates of spontaneous and drug-induced

cataplectic attacks in genetically narcoleptic canines, guided by Drs. Theodore L. Baker and William C. Dement

1979-1980 Stanford Sleep Disorders Clinic, Stanford University Attached electrodes and other physiologic monitoring devices to patients in their homes, using

a portable transmitter to send EEG and other signals to the clinic 1979-1980 Department of Human Biology, Stanford University Searched for an engram involved with a simple conditioned response in the rabbit's motor

cortex under the guidance of Dr. Richard F. Thompson

Clete A. Kushida, M.D., Ph.D., RPSGT 3

1977-1979 Stanford Center for Human Sleep Research, Stanford University Attached electrodes to patients and monitored their EEGs and other parameters during sleep

COURSE TEACHING EXPERIENCE

2009 Course Lecturer, PGY-III Advanced Pharmacology Course (two 1-hour lectures, 1 time/year on insomnia and psychopharmacology of sleep disorders), Department of Psychiatry and Behavioral Sciences, Stanford University, CA

2007-2008 Chair/Organizer, Stanford Sleep Center Grand Rounds for 2007-08 academic year, Division of Sleep Medicine, Stanford University, CA

2002-curr Co-Director, “Sleep Medicine for Medical Students” Psychiatry and Behavioral Sciences Elective Clerkship (PSYC 333A), Stanford University, CA

2000-2004 Course Faculty, Sleep Respiratory Academy of Japan (1 time/year on specific topics of sleep and its disorders), Tokyo, Japan

2000 Course Director, Polysomnographic Technologist Training Program, Stanford University, CA 1999-curr Course Faculty, Sleep Medicine, Interdisciplinary Family Medicine Core Clerkships for Medical

Students (INDE 301A) (3-hour lecture, 10 times/year on specific topics of sleep and its disorders), Stanford University, CA

1998-2010 Course Faculty, Sleep Medicine, Basic Core Psychiatry Clerkship for Medical Students (PSYC 300A) (2-hour lecture, 4 times/year on specific topics of sleep and its disorders), Stanford University, CA

1998-curr Course Lecturer, Sleep Conferences for Sleep Physicians and Surgeons (1-hour, 1 time/year on specific topics of sleep medical and surgical interventions), Stanford University, CA

1998-2006 Course Director, Sleep Conferences for Sleep Physicians and Surgeons (12 times/year on specific topics of sleep medical and surgical interventions), Stanford University, CA

1998-2004 Course Lecturer, Sleep Medicine, Introductory Psychiatry Course for Medical Students (PSYC 201) (1-hour, 1 time/year on specific topics of sleep and its disorders), Stanford University, CA

1998 Course Faculty, Molecular Biology of Sleep, Graduate Student Course, Stanford University, CA

1997-2008 Course Faculty, Sleep, Physician/Technologist Courses, (two 1-hour lectures, 1 time/year on specific topics of sleep and its disorders), School of Sleep Medicine, Honolulu, HI

1997-curr Course Faculty, Sleep and Dreams, Course for Undergraduate students (PSYC 135) (1-hour lecture, 1 time/year on specific topics of sleep and its disorders), Stanford University, CA

1997 Course Director, Managing Sleep Disorders in the Primary Care Setting, Stanford, CA 1996-2000 Course Faculty, Sleep, Physician/Technologist Courses (4 times/year on specific topics of

sleep and its disorders), School of Sleep Medicine, Palo Alto, CA 1995 Course Lecturer, Introductory Psychology Course, Ohlone College, Fremont, CA 1994-curr Lecturer, Stanford Sleep Center Grand Rounds (1-hour lecture, 1 time/year on specific topics

of sleep and its disorders), Division of Sleep Medicine, Stanford University, CA 1994-curr Course Faculty, Sleep Disorders, Physiology of Sleep, and Chronobiology: Clinical Review for

Sleep Medicine Attending Physicians and Clinical Fellows (1-hour lecture, 4 times/year on specific topics of sleep and its disorders), Stanford University, CA

1994-curr Course Faculty, Clinical Review for Polysomnographic Technologists (1-hour lecture, 1 time/year on specific topics of sleep and its disorders), Stanford University, CA

1994 Course Lecturer, Neuropharmacology of Sleep, Undergraduate Course, Stanford University, CA

1994 Course Lecturer, Sleep Physiology and Pathophysiology, Medical Student Course, UC San Diego

1990 Teaching Assistant, Physical Diagnosis, University of Chicago Pritzker School of Medicine, IL 1984 Teaching Assistant, Psychology and Physiology of Sleep and Dreaming, University of

Chicago, IL 1983 Teaching Assistant, Developmental Biopsychology, University of Chicago, IL 1982 Teaching Assistant, Biology of Mammalian Reproduction, University of Chicago, IL

Clete A. Kushida, M.D., Ph.D., RPSGT 4

PUBLICATIONS

Peer-Reviewed Articles (130 total)

Kushida CA, Nichols DA, HolmesTH, Miller R, Griffin K, Cardell C-Y, Hyde PR, Cohen E, Manber R, Walsh JK. SMART DOCS: A new patient-centered outcomes and coordinated-care management approach for the future practice of sleep medicine. Sleep, 2015 Feb 1;38(2):315-26..

Camacho M, Certal V, Abdullatif J, Zaghi S, Ruoff CM, Capasso R, Kushida CA. Myofunctional Therapy to Treat Obstructive Sleep Apnea: A Systematic Review and Meta-analysis. Sleep. 2015 May 1;38(5):669-75.

Certal VF, Zaghi S, Riaz M, Vieira AS, Pinheiro CT, Kushida C, Capasso R, Camacho M.Hypoglossal nerve stimulation in the treatment of obstructive sleep apnea: A systematic review and meta-analysis. Laryngoscope. 2015 May;125(5):1254-64.

Consensus Conference Panel, Watson NF, Badr MS, Belenky G, Bliwise DL, Buxton OM, Buysse D, Dinges DF, Gangwisch J, Grandner MA, Kushida C, Malhotra RK, Martin JL, Patel SR, Quan SF, Tasali E. Recommended Amount of Sleep for a Healthy Adult: A Joint Consensus Statement of the American Academy of Sleep Medicine and Sleep Research Society. J Clin Sleep Med. 2015 Jun 15;11(6):591-2.

Fu C, Jiang L, Zhu F, Liu Z, Li W, Jiang H, Ye H, Kushida CA, Li S. Chronic intermittent hypoxia leads to insulin resistance and impaired glucose tolerance through dysregulation of adipokines in non-obese rats. Sleep Breath. 2015 Feb 28. [Epub ahead of print]

Liu A, Lamendola C, Ariel D, Abbasi F, Kim SH, Cardell J, Tomasso V, Xu S, Patel S, Mojaddidi H, Grove K, Kushida CA, Reaven GM. Usefulness of Fetuin-A to Predict Risk for Cardiovascular Disease Among Patients With Obstructive Sleep Apnea. Am J Cardiol. 2015 Jul 15;116(2):219-24

Watson NF, Badr MS, Belenky G, Bliwise DL, Buxton OM, Buysse D, Dinges DF, Gangwisch J, Grandner MA, Kushida C, Malhotra RK, Martin JL, Patel SR, Quan SF, Tasali E. Recommended Amount of Sleep for a Healthy Adult: A Joint Consensus Statement of the American Academy of Sleep Medicine and Sleep Research Society. Sleep. 2015 Jun 1;38(6):843-4.

Van Den Eeden SK, Albers KB, Davidson JE, Kushida CA, Leimpeter AD, Nelson LM, Popat R, Tanner CM, Bibeau K, Quesenberry CP. Risk of Cardiovascular Disease Associated with a Restless Legs Syndrome Diagnosis in a Retrospective Cohort Study from Kaiser Permanente Northern California. Sleep. 2015 Jul 1;38(7):1009-15.

Wong JK, Maxwell BG, Kushida CA, Sainani KL, Lobato RL, Joseph Woo Y, Pearl RG. Obstructive Sleep Apnea Is an Independent Predictor of Postoperative Atrial Fibrillation in Cardiac Surgery. J Cardiothorac Vasc Anesth. 2015 Mar 26. pii: S1053-0770(15)00187-1. doi: 10.1053/j.jvca.2015.03.024. [Epub ahead of print]

Zhou J, Zhang J, Li Y, Du L, Li Z, Lei F, Wing YK, Kushida CA, Zhou D, Tang X. Gender differences in REM sleep behavior disorder: a clinical and polysomnographic study in China. Sleep Med. 2015 Mar;16(3):414-8.

Kushida CA, Halbower AC, Kryger MH, Pelayo R, Assalone V, Cardell CY, Huston S, Willes L, Wimms AJ, Mendoza J. Evaluation of a new pediatric positive airway pressure mask. J Clin Sleep Med. 2014 Sep 15;10(9):979-84

Bliwise DL, Friedman L, Hernandez B, Zeitzer JM, Kushida CA, Yesavage JA. Nocturia reported in nightly sleep diaries: common occurrence with significant implications? Health Psychol. 2014 Nov;33(11):1362-5. doi: 10.1037/a0034401. Epub 2013 Nov 18.

Camacho M, Zaghi S, Certal V, Abdullatif J, Means C, Acevedo J, Liu S, Brietzke SE, Kushida CA, Capasso R. Inferior turbinate classification system, grades 1 to 4: Development and validation study. Laryngoscope. 2014 Sep 12. doi: 10.1002/lary.24923. [Epub ahead of print]

Cao M, Cardell CY, Willes L, Mendoza J, Benjafield A, Kushida C. A novel adaptive servoventilation (ASVAuto) for the treatment of central sleep apnea associated with chronic use of opioids. J Clin Sleep Med. 2014 Aug 15;10(8):855-61.

Greve DN, Duntley SP, Larson-Prior L, Krystal AD, Diaz MT, Drummond SPA, Thein SG, Kushida CA, Yang R, Dammerman R, Thomas RJ. Effect of armodafinil on cortical activity and working memory in patients With residual excessive sleepiness associated with CPAP-treated OSA: A multicenter fMRI study. J Clin Sleep Med. 2014 Feb 15;10(2):143-53. doi: 10.5664/jcsm.3440.

Huynh NT, Prilipko O, Kushida CA, Guilleminault C. Volumetric brain morphometry changes in patients with obstructive sleep apnea syndrome: Effects of CPAP treatment and literature review. Front Neurol. 2014 Apr 29;5:58.

Clete A. Kushida, M.D., Ph.D., RPSGT 5

Liu A, Cardell J, Ariel D, Lamendola C, Abbasi F, Kim SH, Holmes TH, Tomasso V, Mojaddidi H, Grove K, Kushida CA, Reaven GM. Abnormalities of lipoprotein concentrations in obstructive sleep apnea are related to insulin resistance. Sleep. 2014 Oct 28. pii: sp-00388-14. [Epub ahead of print]

Prilipko O, Huynh N, Thomason ME, Kushida CA, Guilleminault C. An fMRI study of cerebrovascular reactivity and perfusion in obstructive sleep apnea patients before and after CPAP treatment. Sleep Med. 2014 Aug;15(8):892-8.

Quan SF, Budhiraja R, Batool-Anwar S, Gottlieb DJ, Eichling P, Patel S, Shen W, Walsh JK, Kushida CA. Lack of impact of mild obstructive sleep apnea on sleepiness, mood and quality of life. Southwest J Pulm Crit Care. 2014;9(1):44-56.

Quan SF, Budhiraja R, Clarke DP, Goodwin JL, Gottlieb DJ, Nichols DA, Simon RD, Smith TW, Walsh JK, Kushida CA, Phillips B. You still need more than CPAP for OSA patients to lose weight. J Clin Sleep Med. 2014 Mar 15;10(3):349. doi: 10.5664/jcsm.3552.

Sutherland K, Vanderveken OM, Tsuda H, Marklund M, Gagnadoux F, Kushida CA, Cistulli PA. Oral appliance treatment for obstructive sleep apnea: an update. J Clin Sleep Med. 2014 Feb 15;10(2):215-27. doi: 10.5664/jcsm.3460.

Zee PC, Badr MS, Kushida C, Mullington JM, Pack AI, Parthasarathy S, Redline S, Szymusiak RS, Walsh JK, Watson NF. Strategic opportunities in sleep and circadian research: report of the Joint Task Force of the Sleep Research Society and American Academy of Sleep Medicine. Sleep. 2014 Feb 1;37(2):219-27. doi: 10.5665/sleep.3384.

Zhou J, Zhang J, Du L, Li Z, Li Y, Lei F, Wing YK, Kushida CA, Zhou D, Tang X. Characteristics of early- and late-onset rapid eye movement sleep behavior disorder in China: a case-control study. Sleep Med. 2014 Jun;15(6):654-60.

Kuna ST, Benca R, Kushida CA, Walsh J, Younes M, Staley B, Hanlon A, Pack AI, Pien GW, Malhotra A. Agreement in computer-assisted manual scoring of polysomnograms across sleep centers. Sleep. 2013 Apr 1;36(4):583-9. doi: 10.5665/sleep.2550.

Liu A, Kushida CA, Reaven GM. Habitual shortened sleep and insulin resistance: An independent relationship in obese individuals. Metabolism. 2013 Jul 10. S0026-0495(13)00183-2.

Liu A, Kushida CA, Reaven GM. Risk for obstructive sleep apnea in obese, nondiabetic adults varies with insulin resistance status. Sleep Breath. 2013 Mar;17(1):333-8. doi: 10.1007/s11325-012-0696-0. Epub 2012 Apr 7.

Malhotra A, Younes M, Kuna ST, Benca R, Kushida CA, Walsh J, Hanlon A, Staley B, Pack AI, Pien GW. Performance of an automated polysomnography scoring system versus computer-assisted manual scoring. Sleep. 2013 Apr 1;36(4):573-82. doi: 10.5665/sleep.2548.

Maholtra S, Kushida CA. Primary hypersomnias of central origin. Continuum (Minneap Minn). 2013 Feb;19(1 Sleep Disorders):67-85. doi: 10.1212/01.CON.0000427212.05930.c4.

Quan SF, Budhiraja R, Clarke DP, Goodwin JL, Gottlieb DJ, Nichols DA, Simon RD, Smith TW, Walsh JK, Kushida CA. Impact of Treatment with Continuous Positive Airway Pressure (CPAP) on Weight in Obstructive Sleep Apnea. J Clin Sleep Med. 2013 Oct 15;9(10):989-93.

Shin LK, Holbrook AB, Capasso R, Kushida CA, Powell NB, Fischbein NJ, Pauly KB. Improved sleep MRI at 3 tesla in patients with obstructive sleep apnea. J Magn Reson Imaging. 2013 Feb 6. doi: 10.1002/jmri.24029. [Epub ahead of print]

Zaharna M, Rama A, Chan R, Kushida C. A case of positional central sleep apnea. J Clin Sleep Med. 2013 Mar 15;9(3):265-8. doi: 10.5664/jcsm.2496.

Kushida CA, Nichols DA, Holmes TH, Quan SF, Walsh JK, Gottlieb DJ, Simon RD, Guilleminault C, White DP, Goodwin JL,Schweitzer PK, Leary EB, Hyde PR, Hirshkowitz M, Green S, McEvoy LK, Chan C, Gevins A, Kay GG, Bloch DA, Crabtree T, Dement WC. Effects of continuous positive airway pressure on neurocognitive function in obstructive sleep apnea patients: The Apnea Positive Pressure Long-term Efficacy Study (APPLES). Sleep, 2012 Dec 1;35(12):1593-602.

Kushida CA, Nichols DA, Jadrnicek R, Miller R, Walsh JK, Griffin K. Strategies for de-identification and anonymization of electronic health record data for use in multicenter research studies. Medical Care, 50(suppl):S82-S101, 2012.

Berry RB, Kushida CA, Kryger MH, Soto-Calderon H, Staley B, Kuna ST. Respiratory event detection by a positive airway pressure device. Sleep, 35(3):361-367, 2012.

Grunstein RR, Kushida CA. An open letter to the sleep and circadian rhythms community: presidents' viewpoints of the World Sleep Federation (WSF). J Sleep Res. 2012 Dec;21(6):724-5. doi: 10.1111/jsr.12015.

Grunstein RR, Kushida CA. An open letter to the sleep and circadian rhythms community: Presidents' viewpoints of the World Sleep Federation (WSF). Sleep. 2012 Oct 1;35(10):1321-2.

Clete A. Kushida, M.D., Ph.D., RPSGT 6

Grunstein RR, Kushida CA. An open letter to the sleep and circadian rhythms community: presidents' viewpoints of the World Sleep Federation (WSF). Sleep Med Rev. 2012 Oct;16(5):489-90. doi: 10.1016/j.smrv.2012.06.005.

Holmes TH, Nichols DA, Thomander D, Kushida CA. A method for estimating normative distributions for study-specific populations of clinical trials. Contemporary Clinical Trials, 2012; 33 (2): 445-9.

Prilipko O, Huynh N, Schwartz S, Tantrakul V, Kushida C, Paiva T, Guilleminault C. The effects of CPAP treatment on task positive and default mode networks in obstructive sleep apnea patients: An fMRI study. PLoS One. 2012;7(12):e47433. doi: 10.1371/journal.pone.0047433. Epub 2012 Dec 5.

Kushida CA, Berry RB, Blau A, Crabtree T, Fietze I, Kryger MH, Pegram GV, Jr., Penzel T. Positive airway pressure initiation: A randomized controlled trial to assess the impact of therapy mode and titration process on efficacy, adherence, and outcomes. Sleep,34(8):1083-1092, 2011.

Brown DL, Anderson CS, Chervin RD, Kushida CA, Lewin DS, Malow BA, Redline S, Goldman EB. Ethical issues in the conduct of clinical trials in obstructive sleep apnea. J Clin Sleep Med, 7(1):103-8, 2011.

Kuna ST, Badr MS, Kimoff RJ, Kushida C, Lee-Chiong T, Levy P, McNicholas WT, Strollo PJ Jr; ATS/AASM/ACCP/ERS Committee on Ambulatory Management of Adults with OSA. An official ATS/AASM/ACCP/ERS workshop report: Research priorities in ambulatory management of adults with obstructive sleep apnea. Proc Am Thorac Soc. 8(1):1-16, 2011.

Prilipko O, Huynh N, Schwartz S, Tantrakul V, Kim JH, Peralta AR, Kushida C, Paiva T, Guilleminault C. Task positive and default mode networks during a parametric working memory task in obstructive sleep apnea patients and healthy controls. Sleep, 34(3):293-301, 2011.

Quan SF, Chan CS, Dement WC, Gevins A, Goodwin JL, Gottlieb DJ, Green S, Guilleminault C, Hirshkowitz M, Hyde PR, Kay GG, Leary EB, Nichols DA, Schweitzer PK, Simon RD, Walsh JK, Kushida CA. The association between obstructive sleep apnea and neurocognitive performance – the Apnea Positive Pressure Long-term Efficacy Study (APPLES). Sleep, 34(3):303-314, 2011.

Strollo Jr. PJ, Badr MS, Coppola MP, Fleishman SA, Jacobowitz O, Kushida CA. The future of sleep medicine. Sleep,34(12):1613-9, 2011.

Kushida CA, Nichols DA. Obstructive sleep apnea and neurocognitive function. Sleep Medicine Research, 1:4-7, 2010.

Berry RB, Chediak A, Brown LK, Finder J, Gozal D, Iber C, Kushida CA, Morgenthaler T, Rowley JA, Davidson-Ward SL; NPPV Titration Task Force of the American Academy of Sleep Medicine. Best clinical practices for the sleep center adjustment of noninvasive positive pressure ventilation (NPPV) in stable chronic alveolar hypoventilation syndromes. J Clin Sleep Med, 6(5):491-509, 2010.

Bogan RK, Bornemann MA, Kushida CA, Tran PV, Barrett RW; XP060 Study Group. Long-term maintenance treatment of restless legs syndrome with gabapentin enacarbil: a randomized study. Mayo Clin Proc, 85(6):512-21, 2010.

Chen NH, Chuang LP, Yang CT, Kushida CA, Hsu SC, Wang PC, Lin SW, Chou YT, Chen RS, Li HY, Lai SC. The prevalence of restless legs syndrome in Taiwanese adults. Psychiatry Clin Neurosci 64(2):170-8, 2010.

Hening WA, Allen RP, Ondo WG, Walters AS, Winkelman JW, Becker P, Bogan R, Fry JM, Kudrow DB, Lesh KW, Fichtner A, Schollmayer E; SP792 Study Group (Kushida CA). Rotigotine improves restless legs syndrome: a 6-month randomized, double-blind, placebo-controlled trial in the United States. Mov Disord 25(11):1675-83, 2010.

Imamura S, Kushida C. Gabapentin enacarbil (XP13512/GSK1838262) as an alternative treatment to dopaminergic agents for restless legs syndrome. Expert Opin Pharmacother 11(11):1925-32, 2010.

Nguyen PK, Katikireddy CK, McConnell MV, Kushida C, Yang PC. Nasal continuous positive airway pressure improves myocardial perfusion reserve and endothelial-dependent vasodilation in patients with obstructive sleep apnea. J Cardiovasc Magn Reson, 12(1):50, 2010.

Popat RA, Van Den Eeden SK, Tanner CM, Kushida CA, Rama AN, Black JE, Bernstein A, Kasten M, Chade A, Leimpeter A, Cassidy J, McGuire V, Nelson LM. Reliability and validity of two self-administered questionnaires for screening restless legs syndrome in population-based studies. Sleep Med 11(2):154-60, 2010. Epub 2010 Jan 20.

Kushida CA, Becker P, Ellenbogen A, Canafax D, Barrett R, XP052 Study Group. A randomized, double-blind, placebo-controlled study of XP13512/GSK1838262 in patients with RLS. Neurology, 72(5):439-46, 2009.

Kushida CA, Walters AS, Becker P, Thein SG, Perkins AT, Roth T, Canafax D, Barrett RW, XP021 Study Group. A randomized, double-blind, placebo-controlled, crossover study of XP13512/GSK1838262 in the treatment of patients with primary restless legs syndrome. Sleep, 32(2):159-68, 2009.

Clete A. Kushida, M.D., Ph.D., RPSGT 7

Friedman L, Zeitzer JM, Kushida C, Zhdanova I, Noda A, Lee T, Schneider B, Guilleminault C, Sheikh J, Yesavage JA. Scheduled bright light for treatment of insomnia in older adults. J Am Geriatr Soc 57(3):441-52, 2009. Epub 2009 Jan 29.

Walters AS, Ondo WG, Kushida CA, Becker PM, Ellenbogen AL, Canafax DM, Barrett RW; XP045 Study Group, Gabapentin enacarbil in restless legs syndrome: A phase 2b, two-week, randomized, double-blind, placebo-controlled trial. Clin Neuropharmacol, 32:311-20, 2009 Aug 3 (Epub ahead of print).

Kushida CA, Chediak A, Berry RB, Brown LK, Gozal D, Iber C, Parthasarathy S, Quan SF, Rowley JA, Positive Airway Pressure Titration Task Force of the American Academy of Sleep Medicine. Clinical guidelines for the manual titration of positive airway pressure in patients with obstructive sleep apnea. J Clin Sleep Med, 4(2):157-71, 2008.

Kushida CA, Geyer J, Tolson JM, Asgharian A. Patient- and physician-rated measures demonstrate the effectiveness of ropinirole in the treatment of restless legs syndrome. Clin Neuropharmacol, 31(5):281-6, 2008.

Khan A, Auger RR, Kushida CA, Ramar K. Rhythmic movement disorder. Sleep Med, 9(3):329-30, 2008, Epub 2007 Nov 26.

Khan A, Ramar K, Auger RR, Kushida CA. Insomnia and sleep-related movement disorder. Sleep Med, 9(3):325-8, 2008, Epub 2007 Aug 2.

Ramar K, Tippmann-Peikert M, Kushida CA. Sleepiness and brief lapses of consciousness. Sleep Med, 9(8):914-6, 2008. Epub 2007 Nov 26.

Sullivan SS, Kushida CA. Multiple sleep latency test and maintenance of wakefulness test. Chest, 134(4):854-61, 2008.

Kushida CA. Clinical presentation, diagnosis, and quality of life issues in restless legs syndrome. Am J Med, 120:1S1: S4-S12, 2007.

Kushida C, Martin M, Nikam P, Blaisdell B, Wallenstein G, Ferini-Strambi L, Ware JE Jr. Burden of restless legs syndrome on health-related quality of life. Qual Life Res, 16(4):617-24, 2007.

Penzel T, Hirshkowitz M, Harsh J, Chervin RD, Butkov N, Kryger M, Malow B, Vitiello MV, Silber MH, Kushida CA, Chesson AL Jr. Digital analysis and technical specifications. J Clin Sleep Med, 3(2):109-20, 2007.

Walters AS, Lavigne G, Hening W, Picchietti DL, Allen RP, Chokroverty S, Kushida CA, Bliwise DL, Mahowald MW, Schenck CH, Ancoli-Israel S. The scoring of movements in sleep. J Clin Sleep Med, 3(2):155-67, 2007.

Winkelman JW, Sethi KD, Kushida CA, Becker PM, Koester J. Efficacy and safety of pramipexole in restless legs syndrome-Reply. Neurology, 68(19):1641-2, 2007.

Kushida CA. Countermeasures for sleep loss and deprivation. Current Treatment Options in Neurology, 8(5):361-6, 2006.

Kushida CA. Pramipexole for the treatment of restless legs syndrome. Expert Opin Pharmacother, 7(4):441-51, 2006.

Kushida CA. Ropinirole in the treatment of restless legs syndrome. Neuropsychiatric Disease and Treatment, 2(4):407-19, 2006.

Kushida CA, Littner MR, Hirshkowitz M, Morgenthaler T, Alessi CA, Bailey D, Boehlecke B, Brown TM, Coleman Jr. J, Friedman L, Kapen S, Kapur VK, Kramer M, Lee-Chiong T, Owens J, Pancer JP, Swick TJ, Wise MS. Practice parameters for the use of continuous and bilevel positive pressure devices to treat adult patients with sleep-related breathing disorders. Sleep, 29(3):375-80, 2006.

Kushida CA, Morgenthaler TI, Littner MR, Alessi CA, Bailey D, Coleman J Jr, Friedman L, Hirshkowitz M, Kapen S, Kramer M, Lee-Chiong T, Owens J, Pancer JP. Practice parameters for the treatment of snoring and Obstructive Sleep Apnea with oral appliances: an update for 2005. Sleep, 29(2):240-3, 2006.

Kushida CA, Nichols DA, Quan SF, Goodwin JL, White DP, Gottlieb DJ, Walsh JK, Schweitzer PK, Guilleminault C, Simon RD, Leary EB, Hyde PR, Holmes TH, Bloch DA, Green S, McEvoy LK, Gevins A, Dement WC. The Apnea Positive Pressure Long-term Efficacy Study (APPLES): Rationale, design, methods, and procedures. Journal of Clinical Sleep Medicine, 2(3):288-300, 2006.

Maheswaran M, Kushida CA. Restless legs syndrome in children. MedGenMed, 8(2):79, 2006. Winkelman JW, Sethi KD, Kushida CA, Becker PM, Koester J, Cappola JJ, Reess J. Efficacy and safety

of pramipexole in restless legs syndrome. Neurology, 67(6):1034-9, 2006. Epub 2006 Aug 23. Kushida CA, Littner MR, Morgenthaler T, Alessi CA, Bailey D, Coleman J Jr, Friedman L, Hirshkowitz M,

Kapen S, Kramer M, Lee-Chiong T, Loube DL, Owens J, Pancer JP, Wise M. Practice parameters for the indications for polysomnography and related procedures: an update for 2005. Sleep, 28(4):499-521, 2005.

Clete A. Kushida, M.D., Ph.D., RPSGT 8

Kakar RS, Kushida CA. Ropinirole in the treatment of restless legs syndrome. Expert Rev Neurotherapeutics, 5(1):35-42, 2005.

Littner MR, Kushida C, Wise M, Davila DG, Morgenthaler T, Lee-Chiong T, Hirshkowitz M, Daniel LL, Bailey D, Berry RB, Kapen S, Kramer M. Practice parameters for clinical use of the multiple sleep latency test and the maintenance of wakefulness test. Sleep, 28(1):113-21, 2005.

Kushida CA. The use of esophageal manometry in the diagnosis of sleep-related breathing disorders. Conf Proc IEEE Eng Med Biol Soc, 5:3860-3, 2004.

Kushida CA, Allen RP, Atkinson MJ. Modeling the causal relationships between symptoms associated with restless legs syndrome and the patient-reported impact of RLS. Sleep Medicine, 5:485-8, 2004.

Allen R, Becker PM, Bogan R, Schmidt M, Kushida CA, Fry JM, Poceta JS, Winslow D. Ropinirole decreases periodic leg movements and improves sleep parameters in patients with restless legs syndrome. Sleep, 27(5):907-14, 2004.

Atkinson MJ, Allen RP, DuChane J, Murray C, Kushida C, Roth T, RLS Quality of Life Consortium. Validation of the Restless Legs Syndrome Quality of Life Instrument (RLS-QLI): Findings of a consortium of National Experts and the RLS Foundation. Quality of Life Research, 13:679-93, 2004.

Farid M, Kushida CA. Non-rapid eye movement parasomnias. Current Treatment Options in Neurology, 6(4):331-7, 2004.

Guilleminault C, Khramsov A, Stoohs RA, Kushida C, Pelayo R, Kreutzer ML, Chowdhuri S. Abnormal blood pressure in prepubertal children with sleep-disordered breathing. Pediatr Res, 55(1):76-84, 2004.

Littner M, Kushida CA, Anderson WM, Bailey D, Berry RB, Davila DG, Hirshkowitz M, Johnson S, Kapen S, Kramer M, Loube D, Wise M. Practice parameters for the dopaminergic treatment of restless legs syndrome and periodic limb movement disorder. Sleep, 27(3):557-9, 2004.

Rama A, Kushida CA. Restless legs syndrome and periodic limb movement disorder. Med Clin North Am, 88(3):653-67, 2004.

Allen RP, Kushida CA, Atkinson MJ, RLS QoL Consortium. Factor analysis of the International Restless Legs Syndrome Study Group’s Scale for restless legs severity. Sleep Medicine, 4(2):133-5, 2003.

Guilleminault C, Li KK, Philip P, Kushida CA. Anterior cervical spine fusion and sleep disordered breathing. Neurology, 61:97-9, 2003.

Guilleminault C, Powell NB, Martinez S, Kushida C, Raffray T, Palombini L, Philip P. Preliminary observations on the effects of sleep time in a sleep restriction paradigm. Sleep Medicine, 4:177-84, 2003.

Hecht M, Lin L, Kushida CA, Umetsu D, Taheri S, Einen M, Mignot E. Immunosuppression with prednisone in an eight-year-old boy with an acute onset of hypocretin-definciency/narcolepsy. Sleep, 26(7):809-10, 2003.

Littner M, Hirshkowitz M, Kramer M, Kapen S, Anderson WM, Bailey D, Berry RB, Davila D, Johnson S, Kushida C, Loube DI, Wise M, Woodson BT. Practice parameters for using polysomnography to evaluate insomnia: An update. Sleep, 26(6):754-60, 2003.

Littner M, Kushida CA, Anderson WM, Bailey D, Berry RB, Davila DG, Hirshkowitz M, Johnson S, Kapen S, Kramer M, Loube D, Wise M, Johnson SF. Practice parameters for the role of actigraphy in the study of sleep and circadian rhythms: An update for 2002. Sleep, 26(3):237-41. 2003.

Nichols DA, Allen RP, Grauke JH, Brown JB, Rice ML, Hyde PR, Dement WC, Kushida CA. Restless legs syndrome symptoms in primary care: A prevalence study. Arch Int Med, 163:2323-9, 2003.

Schillinger E, Kushida C, Fahrenbach R, Dement WC, LeBaron S. Teaching family medicine medical students about sleep disorders. Fam Med, 35(8):547-9, 2003.

Kushida CA, Giacomini A, Lee MK, Guilleminault C, Dement WC. Technical protocol for the use of esophageal manometry in the diagnosis of sleep-related breathing disorders. Sleep Medicine, 3(2):163-73, 2002.

Brooks S, Kushida CA. Behavioral parasomnias. In: Friedel RO, Evans DL, eds., Curr Psychiatry Rep, 4(5):363-8, 2002.

Littner M, Hirshkowitz M, Davila D, Anderson WM, Kushida CA, Wookson BT, Johnson SF, Wise MS. Practice parameters for the use of auto-titrating continuous positive airway pressure devices for titrating pressures and treating adult patients with obstructive sleep apnea syndrome. Sleep, 25(2):143-7, 2002.

Rama A, Tekwani S, Kushida CA. Sites of obstruction in obstructive sleep apnea. Chest, 122:1139-47, 2002.

Rechtschaffen A, Bergmann BM, Everson CA, Kushida CA, and Gilliland MA. Sleep deprivation in the rat: X. Integration and discussion of the findings. 1989. Sleep, 25(1):68-87, 2002.

Clete A. Kushida, M.D., Ph.D., RPSGT 9

Roth T, Zammit G, Kushida C, Doghramji K, Mathias SD, Wong JM, Buysee DJ. A new questionnaire to detect sleep disorders. Sleep Medicine, 3(2):99-108, 2002.

Kushida CA, Chang A, Gadkary C, Guilleminault C, Carrillo O, Dement WC. Comparison of actigraphic, polysomnographic, and subjective perception of sleep parameters in sleep-disordered patients. Sleep Medicine, 2(5):389-96, 2001.

Kushida CA, Sherrill CM, Hong SC, Palombini L, Hyde P, Dement WC. Cervical positioning for reduction of sleep-disordered breathing in mild-to-moderate OSAS. Sleep and Breathing, 5(2):71-78, 2001.

Guilleminault C, Kim YD, Chowdhuri S, Horita M, Ohayon M, Kushida C. Sleep and daytime sleepiness in upper airway resistance syndrome compared to obstructive sleep apnoea syndrome. Eur Respir J, 17(5):838-47;2001.

Littner M, Johnson SF, McCall WV, Anderson WM, Davila D, Hartse K, Kushida CA, Wise MS, Hirshkowitz M, Woodson BT. Practice parameters for the treatment of narcolepsy: An update for 2000. Sleep, 24 (4):451-466, 2001.

Littner M, Kushida CA, Hartse K, Anderson WM, Davila D, Johnson SF, Wise MS, Hirshkowitz M, Woodson BT. Practice parameters for the use of laser-assisted uvulopalatoplasty: An update for 2000. Sleep, 24(5):603-619, 2001.

Kushida CA, Nichols DA, Simon RD, Young T, Grauke J, Britzmann JB, Hyde PR, Dement WC. Symptom-based prevalence of sleep disorders in an adult primary care population. Sleep and Breathing, 4(1):11-15, 2000.

Li KK, Kushida C, Powell NB, Riley RW, Guilleminault C. Obstructive sleep apnea syndrome: A comparison between Far-East Asian and white men. Laryngoscope, 110(10 Pt 1):1689-93, 2000.

Kushida CA, Rao S, Guilleminault C, Giraudo S, Hsieh J, Hyde P, and Dement WC. Cervical positional effects on snoring and apneas. Sleep Research Online, 2(1):7-10, 1999.

Dement WC, Kushida C. Snoring and sleep quality: everyone deserves a good night’s rest. Mayo Clin Proceedings (Editorial), 74(10):1049, 1999.

Hening W, Allen R, Earley C, Kushida C, Picchietti D, Silber M. The treatment of restless legs syndrome and periodic limb movement disorder: An American Academy of Sleep Medicine Review. Sleep, 22(7):970-999, 1999.

Li KK, Powell NB, Kushida C, Riley RW, Adornato B, Guilleminault C. A comparison of Asian and white patients with obstructive sleep apnea syndrome. Laryngoscope, 109(12):1937-40, 1999.

Kushida CA, Efron B, and Guilleminault C. A predictive morphometric model for the obstructive sleep apnea syndrome. Ann Int Med, 127(8):581-587, 1997.

Kushida CA, Guilleminault C, Clerk AA, and Dement WC. Nasal obstruction and obstructive sleep apnea: a review. Allergy and Asthma Proc, 18(2):69-71, 1997.

Guilleminault C, Kushida C, Stoohs R, Ohayon M, Wilson K, and Clerk A. Should everyone be monitored for upper-airway resistance and how? Sleep, 19(10):S260-2, 1996.

Guilleminault C, Stoohs R, Shiomi T, Kushida C, and Schnittger I. Upper airway resistance syndrome, nocturnal blood pressure monitoring, and borderline hypertension. Chest 109(4):901-8, 1996.

Kushida CA, Clerk AC, Kirsch CM, Hotson JR, and Guilleminault C. Prolonged confusion with nocturnal wandering arising from NREM and REM sleep: A case report. Sleep, 18(9):757-64, 1995.

Kushida CA, Zoltoski RK, and Gillin JC. The expression of m1-m3 muscarinic receptor mRNAs in rat brain following REM sleep deprivation. NeuroReport, 6:1705-8, 1995.

Guilleminault C, Kushida C, and Leger D. Forensic sleep medicine and nocturnal wandering. Sleep, 18(9):721-3, 1995.

Kushida CA, Rye DB, Nummy D, Milton JG, Spire JP, and Rechtschaffen A. Cortical asymmetry of REM sleep EEG following unilateral pontine hemorrhage. Neurology, 41:598-601, 1991.

Kushida CA, Bergmann BM, and Rechtschaffen A. Sleep deprivation in the rat: IV. Paradoxical sleep deprivation. Sleep, 12(1):22-30, 1989.

Kushida CA, Everson CA, Suthipinittharm P, Sloan J, Soltani K, Bartnicke B, Bergmann BM, and Rechtschaffen A. Sleep deprivation in the rat: VI. Skin changes. Sleep, 12(1):42-46, 1989.

Benca RM, Kushida CA, Everson CA, Kalski R, Bergmann BM, and Rechtschaffen A. Sleep deprivation in the rat: VII. Immune function. Sleep, 12(1):47-52, 1989.

Bergmann BM, Everson CA, Kushida CA, Fang VS, Leitch CA, Schoeller DA, Refetoff S, and Rechtschaffen A. Sleep deprivation in the rat: V. Energy use and mediation. Sleep, 12(1):31-41, 1989.

Bergmann BM, Kushida CA, Everson CA, Gilliland MA, Obermeyer W, and Rechtschaffen A. Sleep deprivation in the rat: II. Methodology. Sleep, 12(1):5-12, 1989.

Clete A. Kushida, M.D., Ph.D., RPSGT 10

Everson CA, Gilliland MA, Kushida CA, Pilcher JJ, Fang VS, Refetoff S, Bergmann BM, and Rechtschaffen A. Sleep deprivation in the rat: IX. Recovery. Sleep, 12(1):60-67, 1989.

Rechtschaffen A, Bergmann BM, Everson CA, Kushida CA, and Gilliland MA. Sleep deprivation in the rat: I. Conceptual issues. Sleep, 12(1):1-4, 1989.

Rechtschaffen A, Bergmann BM, Everson CA, Kushida CA, and Gilliland MA. Sleep deprivation in the rat: X. Integration and discussion of the findings. Sleep, 12(1):68-87, 1989.

Dement WC, Allen R, Chase M, Hayes B, Kushida C, Millman R, Roffwarg H, Sassin J, Spielman A, Spire JP, Wooten V, Zorick F. The Medical School Curriculum Consensus Workshop: Consensus Document. Sleep, 11(6):566-70, 1988.

Kushida C, Baker T, and Dement W. Electroencephalographic correlates of cataplectic attacks in narcoleptic canines. Electroencephalography and Clinical Neurophysiology, 61:61-70, 1985.

Non-Peer-Reviewed Articles (68 total)

Camacho M, Kushida CA, Capasso R. 2-year sleep surgery and medicine fellowships for otolaryngologists. Otolaryngol Head Neck Surg. 2015 Apr;152(4):766-7.

Kushida CA. Restless legs syndrome in primary care medicine: Diagnosis and treatment of a common cause of sleep disturbance. Epocrates MobileCME, in press.

Kushida CA. Restless legs syndrome: A common diagnosis you may be missing. Consultant, in press. Masri TJ, Gonzales CG, Kushida CA. Idiopathic hypersomnia. In: Avidan AY, ed., Hypersomnia, Sleep

Medicine Clinics, 7(2):283-90, Philadelphia: Elsevier, 2012. Kushida CA. Shaping the sleep profession of tomorrow. Sleep Review, 11(1): 10-11, January/February

2010. Ramar K, Kushida CA. CPAP and BPAP Titration. In: Berry RB, ed., Positive Airway Pressure Therapy,

Sleep Medicine Clinics, 5(3):335-46, Philadelphia: Elsevier Saunders, 2010. Frenette E, Kushida CA. Primary hypersomnias of central origin. Semin Neurol, 29(4):354-367, 2009.

Epub 2009 Sep 9. Kushida CA. Sleep’s thought leaders weight in. What are the key issues and trends. ADVANCE for

Respiratory Care and Sleep Medicine, 18(7):10, September 2009. Kushida CA. New Stanford Sleep Medicine Center opened in February 2009. San Francisco Medicine:

Journal of the San Francisco Medical Society, 82(3):27, 2009. Kushida CA. AASM President’s viewpoint: Planning for a challenging yet promising future. J Clin Sleep

Medicine, 5(4):301-3, 2009. Rama AN, Zachariah R, Kushida CA. Differentiating nocturnal movements: leg movements, parasomnias,

and seizures. In: Epstein LJ and Kirsch DB, eds., Polysomnography, Sleep Medicine Clinics, 4(3):361-72, Philadelphia: Elsevier Saunders, 2009.

Kushida CA, Chediak A, Berry RB, Brown LK, Gozal D, Iber C, Parthasarathy S, Quan SF, Rowley JA, Positive Airway Pressure Titration Task Force of the American Academy of Sleep Medicine. Response to Johnson K, Johnson D. Letter to the Editor: In reference to clinical guidelines for the manual titration of positive airway pressure in patients with obstructive sleep apnea. J Clin Sleep Med 2008;4:610. J Clin Sleep Med, 4(6):611, 2008.

Kushida CA, Chediak A, Berry RB, Brown LK, Gozal D, Iber C, Parthasarathy S, Quan SF, Rowley JA, Positive Airway Pressure Titration Task Force of the American Academy of Sleep Medicine. Response to Marcus CL. Letter to the Editor: Concerns regarding the pediatric component of the AASM clinical guidelines for the manual titration of positive airway pressure in patients with obstructive sleep apnea. J Clin Sleep Med 2008;4:607. J Clin Sleep Med, 4(6):608-9, 2008.

Kushida CA, Chediak A, Berry RB, Brown LK, Gozal D, Iber C, Parthasarathy S, Quan SF, Rowley JA, Positive Airway Pressure Titration Task Force of the American Academy of Sleep Medicine. Response to Butkov N. Letter to the Editor: Response to a review of the clinical guidelines for the manual titration of positive airway pressure in patients with obstructive sleep apnea. J Clin Sleep Med 2008;4:610. A2Zzz, 17(4):30-1, 2008.

Kushida CA. Clinical case: Giving medical testimony in a patient’s behalf. Virtual Mentor: American Medical Association Journal of Ethics, 10(9):556-9, 2008.

Kushida CA. Key considerations in the diagnosis and management of RLS in the family practice setting. Medscape Neurology. www.medscape.com, 2008.

Sullivan SS, Kushida CA. A good night’s rest does the body best: The importance of breathing well during sleep. San Francisco Medicine: Journal of the San Francisco Medical Society, 81(5):34, 2008.

Verma N, Kushida CA. Restless legs syndrome. British Medical Journal Point in Care, https://pointofcare.bmj.com, 2008.

Clete A. Kushida, M.D., Ph.D., RPSGT 11

Kushida CA. XP13512 treatment of RLS. Pain & the Sensory Symptoms of RLS. eMonograph: Johns Hopkins Medicine eSeminar Series, www.painrls.org, 2007.

Chan A, Kushida CA. Sleep-disordered breathing. American Academy of Neurology Continuum: Sleep Disorders, 13(3):139-152, 2007.

Kushida C. Identification and diagnosis of sleep disorders. In: Narcolepsy: Essentials in Diagnosis and Management, CME-Today, CD-ROM, Volume 4, Issue 2, October 2006.

Kushida C. Interruptions in the sleep cycle: Cause & effect. In: Narcolepsy: Essentials in Diagnosis and Management, CME-Today, CD-ROM, Volume 4, Issue 2, October 2006.

Kushida CA. Restless legs syndrome: Cognitive deficits. Journal Watch Neurology, May 25, 2006. Kushida C. Treatment of narcolepsy. In: Narcolepsy: Essentials in Diagnosis and Management, CME-

Today, CD-ROM, October 2006, Volume 4, Issue 2, 2006. Kushida C, Schwartz JRL. Narcolepsy: Essentials in Diagnosis and Management, CME-Today, 4(2), 6-11,

October 2006. Chan A, Kushida CA. Restless legs syndrome. J Clin Outcomes Management, 13(3):184-94, 2006. Leibowitz SM, Lopes M-C, Andersen ML, Kushida CA. Sleep deprivation and sleepiness caused by sleep

loss. In: Guilleminault C, ed., Excessive Sleepiness, Sleep Medicine Clinics, 1(1):31-45, Philadelphia: Elsevier Saunders, 2006.

Lu E, Kushida CA. Family ties: Research shows that obstructive sleep apnea follows a genetic pattern. ADVANCE for Managers of Respiratory Care, 15(7):43, Sept 1, 2006.

Rama A, Kushida CA. Treatment of RLS in a man with a complicated medical history. Medscape Neurology & Neurosurgery: Case Reports in Clinical Neurology. www.medscape.com, 2006.

Kushida CA. OSA: Reflections on recognition, diagnosis, and treatments. Physician’s Weekly, 2005. Kushida CA. Predictors for patient success and failure during CPAP therapy. ADVANCE for Managers of

Respiratory Care, 14(1):53-5, 2005. Kushida CA. Tingling sensations? Pain in your arms? It could be restless legs syndrome. Bottom

Line/Health, p. 7-9, October, 2005. Kushida CA. Utilizing diagnostic tools to help children sleep better. ADVANCE for Managers of

Respiratory Care,14(6):54, June 1, 2005. Dopheide JA, Kushida CA. Newer options in the management of insomnia. Power-Pak C.E., October

2005. Rama A, Kushida CA. A 6-year-old boy who “can’t sit still.” Medscape Neurology & Neurosurgery: Case

Reports in Clinical Neurology. www.medscape.com, 2005. Rama A, Kushida CA. A young woman with excessive daytime sleepiness. Medscape Neurology &

Neurosurgery: Case Reports in Clinical Neurology. www.medscape.com, 2005. Rama A, Kushida CA. A young woman with RLS, depression, and painful peripheral neuropathy.

Medscape Neurology & Neurosurgery: Case Reports in Clinical Neurology. www.medscape.com, 2005.

Rama A, Kushida CA. Elderly and restless. Medscape Neurology & Neurosurgery: Case Reports in Clinical Neurology. www.medscape.com, 2005.

Rama A, Kushida CA. Pregnant and restless. Medscape Neurology & Neurosurgery: Case Reports in Clinical Neurology. www.medscape.com, 2005.

Rama A, Kushida CA. Review of “Cognitive deficits associated with restless legs syndrome (RLS).” Medscape Neurology & Neurosurgery: Journal Scan. www.medscape.com, 2005.

Rama A, Kushida CA. Review of “Pediatric sleep-related breathing disorders and restless legs syndrome: How children are different” Medscape Neurology & Neurosurgery: Journal Scan. www.medscape.com, 2005.

Rama A, Kushida CA. Review of “Restless legs syndrome, periodic limb movements in sleep, and depression.” Medscape Neurology & Neurosurgery: Journal Scan. www.medscape.com, 2005.

Rama A, Kushida CA. Review of “Secondary causes of restless legs syndrome in older people.” Medscape Neurology & Neurosurgery: Journal Scan. www.medscape.com, 2005.

Rama A, Kushida CA. Review of “Symptoms of attention-deficit/hyperactivity disorder in adults with restless legs syndrome.” Medscape Neurology & Neurosurgery: Journal Scan. www.medscape.com, 2005.

Rama A, Kushida CA. Review of “Variability of periodic leg movements in various sleep disorders: Implications for clinical and pathophysiologic studies.” Medscape Neurology & Neurosurgery: Journal Scan. www.medscape.com, 2005.

Becker PM, Kushida CA, Phillips BA. Expert perspectives in restless legs syndrome. The Treatment Reporter: Neurology, 4:2-18, 2004.

Clete A. Kushida, M.D., Ph.D., RPSGT 12

Chen W, Kushida CA. Treatment of sleepwalking and the periodic limb movement disorders. In: Epler GR, ed., Pulmonary and Critical Care Update Online. Vol. 18, Lesson 8, www.chestnet.org/education/online/pccu, 2004.

Kakar R, Wincor MZ, Kushida CA. Excessive daytime sleepiness: Evaluation and management. U.S. Pharmacist, November 4, suppl:3-15, 2004.

Rama A, Kushida CA. A practical approach to recognizing and managing RLS. Medscape Journal. www.medscape.com, 2004.

Chen W, Kushida CA. Nasal obstruction in sleep-disordered breathing. In: Terris DJ, ed., Surgery for Sleep Apnea, Otolaryngol Clin N America, 36(3):437-60, Philadelphia: Elsevier Science, 2003.

Brooks S, Kushida CA. Recent advances in the understanding and treatment of narcolepsy. Primary Psychiatry, 9(8):30-4, 2002.

Stern MB, Adler CH, Hening WA, Kushida CA, Montplaisir J. Management of restless legs syndrome in neurologic practice. Conversations in Neurology, 1(2):1-17, 2002.

Brooks S, Kushida CA. Recent advances in the understanding and treatment of narcolepsy. TEN: Trends in Evidence-Based Neuropsychiatry, 3(9):43-7, 2001.

Kushida CA. Sleep apnea. J Acad Life Underwriting, 16(2):29-30, 2000. Kushida C. Introductory clinical overview in sleep disorders. Primary Psychiatry, 6(10):47-51, 1999. Kushida CA. Restless legs syndrome and periodic limb movement disorder. MDvista Journal.

www.MDvista.com, 1999. Kushida CA. The insomnias. MDvista Journal. www.MDvista.com, 1999. Kushida CA. The obstructive sleep apnea syndome. MDvista Journal. www.MDvista.com, 1999. Kushida CA. The upper airway resistance syndrome. MDvista Journal. www.MDvista.com, 1999. Kushida CA. New technologies for the obstructive sleep apnea syndrome. RT International, 7(1):62,

1998. Kushida CA. Predicting obstructive sleep apnea syndrome. Emergency Medicine, 30(4):153-156, 1998. Kushida CA. Sleep disorders, EEG Disturbances, and EMF exposure: A review. Proc Intern Workshop

Electromag Fields Non-Specific Health Symptoms, Graz, Austria, 53-60, 1998. Kushida CA. Upper-airway resistance syndrome. RT Journal, 7(1):61-64, 1998. Kushida CA, Guilleminault C, Simon D, Ball E, and Dement WC. Diagnostic and treatment strategies for

the obstructive sleep apnea syndrome. J Clin Outcomes Management, 5(1):49-65, 1998. Kushida CA. Upper-airway resistance syndrome. RT International, 11(5):74-78, 1998. Kushida CA. Allergic rhinitis as a modifiable risk factor for disordered breathing during sleep. Clinical

Courier, 14(9):1-7, 1997. Kushida CA. Obstructive sleep apnea syndrome. RT International, 6(1):103-106, 1997. Kushida CA. The relationship between allergic rhinitis and sleep apnea. Clinical Courier, 16(2):1-7, 1997. Reviews (3 total)

Kushida CA. Book review for Sleep and Quality of Life in Clinical Medicine, Verster JC, Pandi-Perumal SR, Streiner DL (eds), 533 pp, Totowa, NJ, Humana Press, 2008, N Engl J Med, 359(15):1637, 2008.

Kushida CA. Botulinum toxin A: New hope for RLS? Commentary on Rotenberg et al., Successful treatment of recalcitrant restless legs syndrome with botulinum toxin type-A. J Clin Sleep Med, 2(3):279-80, 2006.

Kushida CA, Mahakian C. Book review for Clinical Pharmacology of Sleep, Pandi-Perumal SR, Monti JR (eds), 239 pp, Basel, Switzerland, Birkhäuser Verlag, 2006, Sleep Medicine, 9(1):103, 2007.

Books and/or Manuals (16 total)

Authored

Kushida CA. Primary Care Update: Obstructive Sleep Apnea. Amsterdam: Elsevier, 2009. Buchfurer M, Hening WA, Kushida CA. Restless Legs Syndrome. Chicago, IL: American Academy of

Neurology Enterprises, Inc., 2007. Kushida CA, Giacomini A. The use of esophageal manometry in the diagnosis of sleep-related breathing

disorders. Associated Professional Sleep Societies Coursebook, American Academy of Sleep Medicine, 2001.

Kushida CA. SleepLinkTM User’s Manual. Palo Alto, California: Somnet Systems, Incorporated, 1996. Edited

Kushida CA, editor-in-chief, Encyclopedia of Sleep (4 volumes). Amsterdam: Elsevier, 2013.

Clete A. Kushida, M.D., Ph.D., RPSGT 13

Kushida CA, editor, Pain and Sleep. New York, NY: Taylor and Francis, in progress. Kushida CA, editor, A Guide for Developing, Writing, and Implementing Scientific Research Grant

Proposals. Chicago: American Academy of Sleep Medicine, 2010. Kushida CA, editor, Handbook of Sleep Disorders. New York, NY: Informa Healthcare, 2009. Kushida CA. editor, Obstructive Sleep Apnea, Vol 1: Pathophysiology, Comorbidities, and Consequences.

New York, NY: Informa Healthcare, 2007. Kushida CA. editor, Obstructive Sleep Apnea, Vol 2: Diagnosis and Treatment. New York, NY: Informa

Healthcare, 2007. Kushida CA, editor, Sleep Deprivation, Vol 1: Basic Science, Physiology, and Behavior. New York, NY:

Marcel Dekker, 2005. Kushida CA, editor, Sleep Deprivation, Vol 2: Clinical Issues, Pharmacology, and Sleep Loss Effects.

New York, NY: Marcel Dekker, 2005. Kushida CA, editor, CPAP Manual, Tokyo, Japan: Fuji RC, 2001. Forewards Sadrmirzaei J, Shrivastava D., Mommy Why Does Daddy Snore? in press. Kryger M, Roth T, Dement WC, eds., Principles and Practice of Sleep Medicine (Fifth Edition). St. Louis,

Missouri: Elsevier Saunders, 2011. Chiang RP-Y, Kang S-C, eds., Introduction to Modern Sleep Technology. International Series on Intelligent

Systems, Control, and Automation: Science and Engineering, Volume 64, Dordrecht, Netherlands: Springer, 2012, vii-viii.

Audiovisual Content (1 total) Kushida CA, Primary hypersomnias of central origin. Continuum Audio, American Academy of Neurology,

Volume 02, Issue 01, 2013. Book Chapters (35 total)

Kushida CA. REM sleep and neurocognitive function. In: Mallick B, ed., REM Sleep. Amsterdam: Elsevier, submitted.

Chan, AV, Kushida CA. Multiple sleep latency test. In: Aminoff M, ed., Encyclopedia of Neurological Sciences. Amsterdam: Elsevier, submitted.

Primeau M, Kushdia CA. Studies of fatigue and human performance in patients with sleep disorders. In: Sharafkhaneh A, Moscovitch A, Hirshkowitz M, eds., Principles and Practice of Fatigue Management: Improving Workplace Safety, submitted.

Lin JH, Kushida CA. Treatment of CNS hypersomnias. In: Avidan A, Zee P, eds., Handbook of Sleep Medicine, 2nd ed, in press.

Rama AN, Cho SC, Kushida CA. Normal human sleep. In: Lee-Chiong T, ed., The Wiley Guide to Sleep Medicine: A Concise Reference and Review. New Jersey: Wiley & Sons, Inc., in press.

Rama AN, Zachariah R, Kushida CA. Restless legs syndrome and periodic limb movements and excessive sleepiness. In: Thorpy M, Billiard M, eds., Sleepiness: Causes, Consequences, Disorders, and Treatment. Cambridge, UK: Cambridge University Press, in press.

Verma N, Kushida CA. Restless legs syndrome. In: Pagel J, Ratnas P, ed., Primary Care Sleep Medicie: A Practical Guide (2nd ed.), Springer Science and Business Media, 2014.

Barot N, Kushida CA. Sleep apnea and hypertension: a clinical perspective. In: Culebras A, ed., Sleep, Stroke, and Cardiovascular Disease. Cambridge, UK: Cambridge University Press, 48-63, 2013.

Sesso DM, Chan AV, Kushida CA. Sleep disorders in Asians. In: Chang EC, ed., Handbook of Adult Psychopathology in Asians: Theory, Diagnosis, and Treatment. Oxford, UK: Oxford University Press, Inc., 290-327, 2012.

Barot N, Kushida CA. Significance of deprivation studies. In: Mallick B, Pandi-Perumal SR, McCarley RW, Morrison AR, eds., Rapid Eye Movement Sleep: Regulation and Function. Cambridge, UK: Cambridge University Press, 301-310, 2011.

Bogan RK, Bornemann MA, Kushida CA, Trân PV, Barrett RW; XP060 Study Group. Long‐term maintenance treatment of restless legs syndrome with gabapentin enacarbil: a randomized controlled study. In: Lee-Chiong T, ed., Best of Sleep Medicine 2011. pp. 214-6.

Kushida CA. Clinical case studies III: Disorders of central nervous system hypersomnias. In: Avidan AY, Barkoukis TJ, eds., Review of Sleep Medicine, 3rd ed. Philadelphia, PA: Elsevier, 659-665, 2011.

Clete A. Kushida, M.D., Ph.D., RPSGT 14

Kushida CA, Lin JH, Frenette E. Central nervous system hypersomnias. In: Avidan AY, Barkoukis TJ, eds., Review of Sleep Medicine, 3rd ed. Philadelphia, PA: Elsevier, 452-466, 2011.

Mahmood M, Kushida CA. Excessive daytime sleepiness. In: Aminoff Mj, Boller F, Swaab DF, eds., Handbook of Clinical Neurology: Sleep Disorders Part II (Volume 99, 3rd Series edited by Montagna P, Chokroverty S). Amsterdam, The Netherlands:Elsevier, 825-31, 2011.

Kushida CA, Becker PM, Ellenbogen AL, Canafax DM, Barrett RW; XP052 Study Group. Randomized, double-blind, placebo-controlled study of XP13512/GSK1838262 in patients with RLS. In: Lee-Chiong T, ed., Best of Sleep Medicine 2010. pp. 167-9.

Cao M, Guilleminault C, Kushida CA. Clinical features and evaluation of obstructive sleep apnea and upper airway resistance syndrome. In: Kryger M, Roth T, Dement WC, eds., Principles and Practice of Sleep Medicine (Fifth Edition). St. Louis, Missouri: Elsevier Saunders, 2011, pp. 1206-18.

Sinha D, Kushida CA. Sleep deprivation and its effects (Public, Medical Profession). In: Chokroverty S, Sahota P. Acute and Emergent Events in Sleep Disorders. New York, NY: Oxford University Press, pp. 74-92, 2011.

Smith HS, Webster LR, Gallati C, Kushida CA. Pain and sleep. In: Smith HS, ed., Current Therapy in Pain. Philadelphia, PA: Saunders Elsevier, 363-372, 2009.

Kushida CA. Funding, writing, and obtaining grants. In: Butkov N, Lee-Chiong T, eds., Fundamentals of Sleep Technology. Philadelphia: Lippincott Williams & Wilkins, 671-8, 2007.

Chan AV, Kushida CA. Overview of sleep. In: Ondo, WG, ed., Restless Legs Syndrome: Diagnosis and Treatment. New York: Informa Healthcare, 1-14, 2007.

Ramar K, Kushida CA. Bilevel positive pressure airway devices and titration of bilevel positive airway pressure. In: Butkov N, Lee-Chiong T, eds., Fundamentals of Sleep Technology. Philadelphia: Lippincott Williams & Wilkins, 461-6, 2007.

Yuen KM, Kushida CA. Economic impact of sleep loss, sleepiness, and sleep disorders. In: Léger D, Pandi-Perumal SR, eds., Sleep Disorders: Their impact on public health. New York, NY: Informa Healthcare, 175-191, 2007.

Rama AN, Cho SC, Kushida CA. Normal human sleep. In: Lee-Chiong T, ed., Sleep: A Comprehensive Handbook. New Jersey: Wiley & Sons, Inc., 3-9, 2006.

Afifi L, Kushida CA. Multiple sleep latency test. In: Guilleminault, ed., Clinical Neurophysiology of Sleep and Its Disorders, Handbook of Clinical Neurophysiology Series. Amsterdam: Elsevier, 2005.

Chang J, Kushida CA. Polysomnography. In: Terris DJ and Goode RL, ed., Surgical Management of Sleep Apnea and Snoring. New York, NY: Taylor and Francis, 2005, pp. 81-94.

Rama A, Cho SC, Kushida CA. NREM-REM sleep. In: Guilleminault, ed., Clinical Neurophysiology of Sleep and Its Disorders, Handbook of Clinical Neurophysiology Series. Amsterdam: Elsevier, 2005.

Afifi L, Kushida CA. The multiple sleep latency test. In: Aminoff MJ, Daroff RB, eds., Encyclopedia of the Neurological Sciences. San Diego, California: Academic Press, 2003, pp. 261-4.

Kuo T, Kushida CA. The treatment efficacy of behavioral interventions for sleep apnea, periodic limb movement disorder and narcolepsy. In: Perlis ML, Lichstein KL, eds., Treating Sleep Disorders: The Principles and Practice of Behavioral Sleep Medicine. New York, New York: John Wiley & Sons, Inc., 136-165, 2003.

Rama A, Kushida CA. Sleep-wake cycle. In: Aminoff MJ, Daroff RB, eds., Encyclopedia of the Neurological Sciences. San Diego, California: Academic Press, 2003, pp. 308-9.

Kushida CA. Sleep disorders. In: Ramachandran VS, ed., Encyclopedia of the Human Brain. San Diego, California: Academic Press, 2002.

Kushida CA. Sleep and its disorders. In: The Americana Annual 2000: Yearbook of the Encyclopedia Americana. Canada: Grolier Inc., 91-96, 2000.

Kushida CA. Sleep and the immune system. In: The Doctor’s Book of Home Remedies for Colds and Flus. Emmaus, Pennsylvania: Rodale Press, 2000.

Kushida CA, Simmons D. Use of in-situ hybridization histochemistry to study muscarinic receptor mRNA expression in brains of sleep-deprived rats. In: Lydic R, ed., Molecular Regulation of Conscious States. London: CRC Press, 119-129, 1998.

Kilduff TS and Kushida CA. Circadian regulation of sleep. In: Chokroverty S, ed., Sleep Disorders Medicine: Basic Science, Technical Considerations, and Clinical Aspects (2nd Edition). Philadelphia: Butterworth Heinemann, 135-148, 1999.

Bergmann B, Everson C, Gilliland M, Kushida C, Obermeyer W, Pilcher J, Prete F, and Rechtschaffen A. Sleep deprivation and thermoregulation. In: Horne JA, ed., Sleep 1988. Stuttgart: GF Verlag, 91-95, 1989.

Clete A. Kushida, M.D., Ph.D., RPSGT 15

Abstracts (160 total)

Kushida CA, Cardell C. Comparison of new level 3 and 4 portable monitors for home sleep testing vs. in-lab polysomnography. Twenty-Sixth Annual Meeting of the Associated Professional Sleep Societies, Boston, MA, June 13, 2012.

Kushida C, Bogan RK, Ellenbogen AL, Becker PM, Ball E, Ondo W, Williams NJ, Caivano C. Gabapentin enacarbil improves restless legs syndrome symptoms and subjective measures of sleep in subjects with primary restless legs syndrome with and without severe sleep disturbance: Secondary analyses from two studies. Sleep, 33(Suppl):A265, 2010.

Arzouman A, Maung C, Hyde PR, Dement WC, Kushida CA. Sleep problems in childhood incest survivors. Sleep, 33(Suppl):A236, 2010.

Bogan RK, Ellenbogen AL, Ball E, Ondo W, Kushida C, Williams NJ, Caivano C. An evaluation of restless legs syndrome symptom augmentation in subjects treated with gabapentin enacarbil for 12 weeks: Secondary integrated analyses from two studies. Sleep, 33(Suppl):A264, 2010.

Bogan RK, Cramer Bornemann MA, Kushida C, Barrett RW. Gabapentin enacarbil maintains improvements in sleep during long-term treatment in subjects with moderate-to-severe primary restless legs syndrome. Sleep, 33(Suppl):A264, 2010.

Mah CD, Kushida C. Single-blind study of mattress designed to improve sleep quality. Sleep, 33(Suppl):A377, 2010.

Prilipko O, Huynh NT, Kushida C, Guilleminault C. An fMRI study of cerebral vascular reactivity in untreated OSA patients and healthy controls. Sleep, 33(Suppl):A116, 2010.

Kushida CA, Becker PM, Ellenbogen AL, Canafax DM, Barrett RW. Gabapentin enacarbil relieves the pain associated with restless legs syndrome (RLS). Neurology, 72(11):A337, 2009.

Kushida CA, Cardell C, Black S, Khouzam A. Comparison of a new type 3 portable monitor for OSA detection vs. in-lab polysomnography. Sleep, 32(Suppl):A385, 2009.

Arzouman AK, Nolan K, Yenikomshian H, Cardell C, Tekwani S, Patil T, Hyde PR, Dement WC, Kushida CA. Effects of low-dose acetazolamide on sleep in mountaineers at high altitude. Sleep,32(Suppl):A210, 2009.

Barrett RW, Kushida CA, Becker PM, Ellenbogen AL, Canafax DM. XP13512/GSK1838262 treats the pain associated with restless legs syndrome. 25th Annual American Academy of Pain Medicine Meeting, Honolulu, Hawaii, January 28-31, 2009.

Becker PM, Kushida CA, Ellenbogen AL, Canafax DM, Barrett RW. Gabapentin enacarbil improves sleep in subjects with moderate-to-severe primary restless legs syndrome. Sleep, 32(Suppl):A299, 2009.

Becker PM, Kushida CA, Ellenbogen AL, Canafax DM, Barrett RW. Gabapentin enacarbil improves mood, quality of life, and functioning in subjects with primary restless legs syndrome. Sleep, 32(Suppl):A297, 2009.

Becker PM, Kushida CA, Ellenbogen AL, Canafax DM, Monaghan ET, Barrett RW. Gabapentin enacarbil improves mood, quality of life (QoL) and functioning in subjects with primary restless legs syndrome (RLS). Society of Biological Psychiatry 64th Annual Scientific Convention and Meeting, Vancouver, CN, May 14-16, 2009.

Becker PM, Kushida CA, Ellenbogen AL, Canafax DM, Barrett RW. Gabapentin enacarbil 1200 mg improves sleep in subjects with moderate-to-severe primary restless legs syndrome (RLS). 162nd Annual Meeting of the American Psychiatric Association, San Francisco, CA, May 16-21, 2009.

Becker PM, Kushida CA, Ellenbogen AL, Canafax DM, Monaghan ET, Barrett RW. Gabapentin enacarbil improves sleep in subjects with moderate-to-severe primary restless legs syndrome (RLS). Biol Psychiatr, 65(8):215s, 2009.

Becker PM, Kushida CA, Ellenbogen AL, Canafax DM, Barrett RW. Gabapentin enacarbil improves sleep in subjects with moderate-to-severe primary restless legs syndrome (RLS). Neurology, 72(11):A336, 2009.

Bogan RK, Cramer Bornemann MA, Kushida CA, Tran PV, Barrett RW. The maintenance of efficacy and long-term tolerability of gabapentin enacarbil compared with placebo in subjects with restless legs syndrome (RLS). Neurology, 72(11):A337, 2009.

Caivano CK,Kushida CA,Becker PM,Ellenbogen AL,Canafax DM,Barrett RW. Efficacy and safety of gabapentin enacarbil in primary restless legs syndrome. 21st Annual Meeting of the Academy of Managed Care Pharmacy, Orlando, FL, April 15-18, 2009.

Canafax DM, Ellenbogen AL, Kushida CA, Becker PM, Barrett RW. Gabapentin enacarbil improves mood, quality of life and functioning in subjects with moderate-to-severe primary restless legs syndrome. 28th Annual Scientific Meeting of the American Pain Society, San Diego, CA, May 7-9, 2009.

Clete A. Kushida, M.D., Ph.D., RPSGT 16

Canafax DM, Kushida CA, Becker PM, Ellenbogen AL, Monaghan ET, Barrett RW. Gabapentin enacarbil relieves the pain associated with restless legs syndrome. 28th Annual Scientific Meeting of the American Pain Society, San Diego, CA, May 7-9, 2009.

Canafax DM, Kushida CA, Becker PM, Ellenbogen AL, Monaghan ET, Barrett RW. Gabapentin enacarbil 1200 mg relieves pain associated with moderate-to-severe restless legs syndrome (RLS). 162nd Annual Meeting of the American Psychiatric Association, San Francisco, CA, May 16-21, 2009.

Canafax DM, Calloway M, Ellenbogen AL, Kushida CA, Becker PM, Barrett RW. Gabapentin enacarbil improves mood, QoL and daily functioning in subjects with primary restless legs syndrome (RLS). Neurology, 72(11):A336, 2009.

Canafax DM, Kushida CA, Becker PM, Ellenbogen AL, Canafax DM, Barrett RW. Gabapentin enacarbil relieves pain associated with restless legs syndrome. Sleep, 32(Suppl):A299, 2009.

Cramer Bornemann MA, Bogan RK, Kushida CA, Tran PV, Barrett RW. A maintenance of efficacy study of gabapentin enacarbil versus placebo in subjects with restless legs syndrome. Sleep, 32(Suppl):A304, 2009.

Cramer Bornemann MA, Bogan RK, Kushida CA, Tran PV, Barrett RW. The maintenance of efficacy and long-term tolerability of gabapentin enacarbil compared with placebo in subjects with restless legs syndrome. 13th International Congress of Parkinson’s Disease and Movement Disorders, Paris, France, June 7-11, 2009.

DeRossett SE, Kushida CA, Becker PM, Ellenbogen AL, Canafax DM, Barrett RW. Gabapentin enacarbil improves sleep in subjects with moderate-to-severe primary restless legs syndrome. 13th International Congress of Parkinson’s Disease and Movement Disorders, Paris, France, June 7-11, 2009.

DeRossett SE, Kushida CA, Becker PM, Ellenbogen AL, Canafax DM, Barrett RW. Gabapentin enacarbil relieves pain associated with restless legs syndrome. 13th International Congress of Parkinson’s Disease and Movement Disorders, Paris, France, June 7-11, 2009.

Ellenbogen AL, Becker PM, Kushida CA, Canafax DM, Barrett RW. Gabapentin enacarbil improves mood, quality of life and functioning in subjects with primary restless legs syndrome. 13th International Congress of Parkinson’s Disease and Movement Disorders, Paris, FR, June 7-11, 2009.

Ellenbogen AL, Becker PM, Kushida CA, Canafax DM, Monaghan ET, Barrett RW. Gabapentin enacarbil improves mood, quality of life, and functioning in subjects with moderate-to-severe primary restless legs syndrome. 162nd Annual Meeting of the American Psychiatric Association, San Francisco, CA, May 16-21, 2009.

Huynh NT, Prilipko O, Tantrakul V, Nichols D, Leary E, Kushida C, Guilleminault C. FMRI study of CPAP treatment on verbal memory encoding in obstructive sleep apnea patients in comparison to healthy controls. Sleep, 32(Suppl):A224, 2009.

Prilipko O, Huynh N, Tantrakul V, Leary E, Nichols D, Henry M, Kushida C, Guilleminault C. Differences in cerebral activation on a visuo-spatial working memory task in obstructive sleep apnea patients and healthy controls. Sleep, 32(Suppl):A225, 2009.

Kushida C, Ellenbogen A, Becker P, Canafax D, Tran P. A randomized, double-blind, placebo-controlled study to assess the efficacy and tolerability of XP13512 1200 mg in patients with restless legs syndrome. Neurology, 70(11)(Suppl 1): A409, 2008.

Kushida CA, Yang P, Katikireddy C, Nguyen P, Cardell C-Y, Manugian A, Wong J, Holmes TH, Nichols DA, Leary E. Apnea Positive Pressure Long-term Efficacy Cardiovascular Outcomes Research Study (APPLE CORS): Preliminary study. Sleep, 31(Suppl):A139, 2008.

Arzouman AK, Sherrill C, Tu T, Cardell C-Y, Hyde PR, Dement WC, Kushida CA. Effects of sleep deprivation, sleep satiation, and ad-libitum sleep conditions on daytime sleep latencies, drowsiness, and vigilance tasks in college students. Sleep, 31(Suppl):A113, 2008.

Becker PM, Kushida CA, Ellenbogen AL, Canafax DM, Tran P. XP13512 reduced restless legs syndrome symptoms and associated sleep impairment: Results of a double-blind, randomized, placebo-controlled study. Sleep, 31(Suppl):A268, 2008.

Ellenbogen AL, Kushida CA, Becker PM, Canafax DM, Tran P. XP13512/GSK1838262 1200 mg provides symptomatic relief in restless legs syndrome patients: A randomized, double-blind, placebo-controlled study. Movement Disorders, 23(1):S364, 2008.

Huynh NT, Prilipko O, Peralta AR, Kim JH, Tantrakul V, Lee MS, Guilleminault C, Kushida CA. A fMRI study of verbal memory encoding in obstructive sleep apnea patients”, J Sleep Res, 17 (Suppl.1):O72, 2008.

Prilipko O, Huynh NT, Peralta AR, Tantrakul V, Kim JH, Lee MS, Guilleminault C, Kushida CA. A visual working memory parametric fMRI study in obstructive sleep apnea patients”, J Sleep Res, 17 (Suppl.1):O73, 2008.

Clete A. Kushida, M.D., Ph.D., RPSGT 17

Prilipko O, Huynh N, Peralta A-R, Tantrakul V, Kim J, Lee M, Henry M, Guilleminault C, Kushida C. Parametric fMRI study of working memory in obstructive sleep apnea patients. Sleep, 31(Suppl): A152, 2008.

Prilipko O, Huynh N, Tantrakul V, Peralta AR, Kim JH, Guilleminault C, Schwartz S, Kushida CA. An event-related fMRI study of verbal memory encoding in obstructive sleep apnea patients. Ann Neurol, 64:S29, 2008.

Rowbotham MC, Kushida CA, Becker PM, Ellenbogen AL, Canafax DM, Barrett RW. XP13512 1200 mg treats the pain and discomfort associated with restless legs syndrome: PIVOT RLS I. 11th International Conference on the Mechanisms and Treatment of Neuropathic Pain, Hamilton, Bermuda, November 6-8, 2008.

Zeitzer J, Friedman L, Zhdanova I, Lin L, Kushida C, Yesavage J. Genetic polymorphism in clock predicts timing of circadian light sensitivity in humans. Sleep, 31(Suppl): A365, 2008.

Kushida CA, Albrecht S, Koester J. Pramipexole improves daytime symptoms among patients with restless legs syndrome (RLS) with impaired daytime function. Mov Disorders, 22(Suppl16):S273, 2007.

Kushida CA, Winkelman JW, Lainey E, Albrecht S, Koester J. Pramipexole did not induce orthostatic hypotension or affect blood pressure or pulse in patients with restless legs syndrome. P1160. 11th European Federation of Neurological Societies Congress, Brussels, Belgium, August 25-28, 2007.

Katikireddy C, Nguyen P, Won C, Cardell C-Y, Nichols D, Leary E, McConnell M, Holmes TH, Kushida CA, Yang P. Multimodality cardiovascular imaging detects improvement of subclinical microvascular dysfunction with continuous positive airway pressure therapy in patients with obstructive sleep apnea: A prospective, randomized, double-blinded study. Circulation, 116(II):846, 2007.

Tran P, Kushida CA, Becker PM, A. L. Ellenbogen AL, Walters AS, Canafax DM. XP13512 is well-tolerated and effective in treating symptoms and improving mood in moderate to severe RLS: Results of a 2-week, randomized, double-blind, placebo-controlled exploratory trial. Biol Psychiatr, 61(8):238S, 2007.

Zee PC, Winkelman JW, Sethi KD, Kushida CA, Becker PM, Koester J. Sleep self-assessment by visual analogue scales (VASs) in a 12-week U.S. trial of pramipexole for restless legs syndrome (RLS). Sleep Medicine, 8(Suppl 1):S71, 2007.

Kushida C, Becker P, Ellenbogen A, Canafax DM. XP13512 improves restless legs syndrome (RLS) patient sleep and symptoms in two double-blind, randomized, placebo-controlled studies. Ann Neurol, 60(Suppl10):S83, 2006.

Kushida C, Becker P, Ellenbogen A, Walters AS, Canafax D. XP13512 is well-tolerated and effective in treating moderate to severe RLS in a 2-week, randomized, double-blind, placebo-controlled exploratory trial. Neurology, 66(5):A8, 2006.

Kushida C, Becker P, Perkins T, Thein S, Walters AS, Canafax D. XP13512 improves symptoms and sleep disturbance in RLS patients: Results of a 2-week, randomized, double-blind, placebo-controlled cross-over polysomnography trial. Sleep, 29(Suppl): A278, 2006.

Kushida CA, Earl NL. Improvements in symptom-related sleep disturbance during ropinirole treatment in patients with restless legs syndrome (RLS). Sleep, 29(Suppl): A280, 2006.

Kushida CA, Tolson JM. Ropinirole improves quality of life in patients with restless legs syndrome (RLS) requiring extended treatment coverage. NR816. 159th Annual Meeting of the American Psychiatric Association, Toronto, CN, May 20-25, 2006.

Kushida CA, Tolson JM. Ropinirole in restless legs syndrome requiring extended treatment coverage. NR815. 159th Annual Meeting of the American Psychiatric Association, Toronto, CN, May 20-25, 2006.

Kushida CA, Tolson JM. Ropinirole is an effective treatment for patients with restless legs syndrome (RLS) needing extended treatment coverage. Neurology, 66:5(suppl2):P02.029:A082, 2006.

Bogan RK, Hosford DA, Earl NL. Ropinirole extended treatment coverage in restless legs syndrome: Patient- and physician-reported efficacy. NR751. 159th Annual Meeting of the American Psychiatric Association, Toronto, CN, May 20-25, 2006.

Canafax DM, Kushida CA, Becker PM, Ellenbogen AL, Walters AS. XP13512 improves symptoms in moderate to severe restless legs syndrome in a 2-week, randomized, double-blind, placebo-controlled exploratory trial. American College of Clinical Pharmacy 2006 Annual Meeting, St. Louis, MO, October 26-29, 2006.

Canafax DM, Kushida CA, Becker PM, Thomas PA, Thein SG, Walters AS, Roth T. XP13512 improves symptoms and sleep disturbance in RLS patients: results of a 2-week, randomized, double-blind,

Clete A. Kushida, M.D., Ph.D., RPSGT 18

placebo-controlled cross-over polysomnography trial. American College of Clinical Pharmacy 2006 Annual Meeting, St. Louis, MO, October 26-29, 2006.

Corbin AE, Sethi KD, Kushida CA, Becker PM, Koester J, Cappola JJ, Reess J, Winkelman JW. Pramipexole treatment rapidly improves patient ratings of restless legs syndrome symptoms. Sleep, 29(Suppl): A283, 2006.

Ellenbogen AL, Kushida CA, Becker PM, Walters AS, Canafax DM. XP13512/ASP8825 improves RLS symptoms: Results of two phase II clinical studies. Mov Disorders, 21(Suppl15):S443, 2006.

Friedman LF, Kushida CA, Hernandez B, Yesavage JA. Primary insomnia study participants compared with participants of a memory training study. Sleep, 29(Suppl): A262, 2006.

Spira AP, Friedman LF, Kushida CA, Hernandez B, Aulakh JS, Sheikh JI, Yesavage JA. Sleep, sub-clinical anxiety symptoms, and daytime dysfunction in older adults with primary insomnia. Sleep, 29(Suppl): A264, 2006.

Walters AS, Kushida CA, Becker PM, Ellenbogen AL, Canafax DM. XP13512 improves restless legs syndrome (RLS) patient sleep and symptoms in two double-blind, randomized, placebo-controlled studies. American Neurological Association 2006 Annual Meeting, Chicago, IL, October 8-11, 2006.

Winkelman JW, Sethi KD, Kushida CA, Becker PM, Koester J, Cappola JJ, Reess J. Effects of pramipexole on subjective measures of sleep quality and symptom severity in patients with restless legs syndrome. Sleep, 29(Suppl): A281, 2006.

Winkelman JW, Sethi KD, Kushida CA, Becker PM. Pramipexole improves a broad range of facets of restless legs syndrome. Mov Disorders, 21(Suppl15):S430, 2006.

Winkelman JW, Sethi KD, Kushida CA, Becker PM, Koester J, Cappola JJ, Reess J. Pramipexole improves quality of life in patients with RLS: Results of a 12-week, placebo-controlled, fixed-dose study. Neurology, 66(5):A80, 2006.

Winkelman JW, Sethi KD, Kushida CA, Becker PM. Pramipexole is not affected by therapy for concomitant disease in patients with restless legs syndrome. Mov Disorders, 21(Suppl15):S437, 2006.

Winkelman JW, Sethi KD, Kushida CA, Becker PM, Koester J, Cappola JJ, Reess J. Pramipexole is efficacious and safe in treating patients with RLS. Neurology, 66(5):A80, 2006.

Winkelman JW, Sethi KD, Kushida CA, Becker PM, Koester J, Cappola JJ, Reess J. Sustained improvement in quality of life during pramipexole therapy for restless legs syndrome. J Sleep Res, 15(Suppl1):180, 2006.

Yenikomshian HA, Kushida CA, Friedman LF, Hernandez B, Yesavage JA. Comparison between actigraphy and sleep diaries in elderly insomnia patients undergoing long-term light therapy. Sleep, 29(Suppl): A260, 2006.

Ziman RB, Earl NL, Kushida CA, Watson CB, Giorgi L. Ropinirole is an effective treatment for restless legs syndrome (RLS) in patients who have failed other therapies. American Academy of Neurology, San Diego, CA, USA, April 1-8, 2006. Neurology, 66:5(suppl2):P02.026:A081, 2006.

Kushida CA, Cardell C, Bradley M, Buckley TM, Chang J, Tu T, Hyde PR, Dement WC. Improvement in PLMD-associated daytime sleepiness with modafinil in a randomized, double-blinded, placebo-controlled trial. Sleep, 28(Suppl):A263, 2005

Kushida CA, Kwong WJ. Beneficial effects of ropinirole in reducing the impact of restless legs syndrome (RLS) on sleep and quality-of-life (QoL). American College of Rheumatology 2005 Annual Scientific Meeting, San Diego, CA, November 13-17, 2005.

Kushida CA, Martin MC, Nikam P, Blaisdell B, Ferini-Strambi L, Ware Jr. JE. Restless legs syndrome places a substantial burden on the health-related quality of life of US patients. Neurology, 64(Suppl 1):A41, 2005.

Kushida CA, Nolan K, Yenikomshian HA, Cardell C, Tekwani S, Patil T, Gianotti A, Evans J, Hyde PR, Dement WC. Effects of low-dose acetazolamide on sleep and sleep-disordered breathing during a controlled trial at high altitude. Sleep, 28(Suppl):A36, 2005.

Ferini-Strambi L, Martin MC, Nikam P, Blaisdell B, Kushida CA, Ware Jr. JE, Kirsch J. Restless legs syndrome places a substantial burden on the health-related quality of life of European patients. Sixteenth International Congress on Parkinson’s Disease and Related Disorders, PT029.13, Berlin, Germany, June 5-9, 2005.

Friedman LF, Kushida CA, Hernandez B, Yesavage JA. Changes in POMS, GDS, and Epworth in response to light treatment for insomnia in older adults. Sleep, 28(Suppl):A226, 2005.

Iturbe J, Kushida CA, Garcia G. Sleep disturbance in cirrhotic patients. Sleep, 28(Suppl):A292, 2005 Martin MC, Nikam P, Blaisdell B, Kushida CA, Ferini-Strambi L, Ware Jr. JE. Functional limitations, mental

health, and resource use associated with the health-related quality of life of patients with restless legs syndrome. Value in Health, 8(3):320, 2005.

Clete A. Kushida, M.D., Ph.D., RPSGT 19

Martin MC, Nikam P, Blaisdell B, Kushida CA, Ferini-Strambi L, Ware Jr. JE. Restless legs syndrome places a substantial burden on the health-related quality of life of United States and European patients. Value in Health, 8(3):320, 2005.

Martin MC, Nikam P, Blaisdell B, Kushida CA, Ferini-Strambi L, Ware Jr. JE, Kirsch J. Health-related quality of life burden of RLS: A comparative account of US and European patient samples. Eur J Neurol, 12(Suppl2):104, 2005.

Winkelman J, Sethi K, Kushida C, Becker P, Mahowald M, Reess J, Cappola J. Pramipexole is efficacious and safe in treating RLS patients: results of a 12 week placebo controlled, fixed dose study. World Association of Sleep Medicine (WASM) First World Congress 2005, Berlin, Germany, October 15-18, 2005.

Kushida C, Becker P, Bogan R, Schmidt M, Fry J, Poceta S, Winslow D, Allen R. The RESET PLM Study: The effects of ropinirole treatment on the motor symptoms implicated in delayed sleep onset and sleep disturbance. Neurology, 62(Suppl 5):A54-55, 2004.

Kushida CA, Kuo T, McEvoy L, Gevins A, Guilleminault C, Dement WC. Apnea Positive Pressure Long-Term Efficacy Study (APPLES): Preliminary studies. Sleep, 27(Suppl):A181, 2004.

Friedman L, Kushida C, Hernandez B, Wakabayashi E, Tu T, Wicks D, Mumenthaler MS, Yesavage JA. Comparison of sleep parameters by AHI values in older insomniacs. Sleep, 27(Suppl):A276, 2004.

Nichols DA, Kushida CA, Allen RP, Grauke JH, Brown JB, Rice ML, Hyde PR, Dement WC. Exploring ferritin levels from an age- and gender-matched primary care population of patients with and without symptoms of RLS. Sleep, 27(Suppl):A299, 2004.

Kushida CA, Kuo TF, Manber R, Cardell C, Behari S, Hyde P, Dement WC. Polysomnographic and REMview assessment of treatment outcomes in patients with insomnia. Sleep, 26(Suppl):A292, 2003.

Chan AQ, Kushida CA, Chan EA, Mandreza RY, Chan EL, Chan MP. Cardiovascular syndrome among Asian Americans with obstructive sleep apnea. Pacing and Cardiac Electrophysiology, 26(2p2):S108, 2003.

Chan AQ, Kushida CA, Mandreza RY, Chen ZW, Chan MP. High prevalence of silent myocardial ischemia amongst Asian Americans. Second Asia Pacific Scientific Forum, Honolulu, HI. www.americanheart.org. Abstract number P72, June 9, 2003.

Friedman LF, Kushida C, Hernandez B, Mahapatra D, Tu T, Yesavage JA. Assessment of neurocognitive functioning, sleep quality, and sleepiness in older insomnia subjects. Sleep, 26(Suppl):A315, 2003.

Friedman LF, Kushida C, Hernandez B, Mumenthaler MS, Tu T, Yesavage JA. Effectiveness of the Global Sleep Assessment Questionnaire in distinguishing two older community-dwelling groups. Sleep, 26(Suppl):A169, 2003.

Kuo TF, Kushida CA, Manber R, Cardell C, Behari S, Hyde P, Dement WC. Treatment outcome of group cognitive-behavioral therapy for insomnia. Sleep, 26(Suppl):A314, 2003.

Nichols DA, Kushida CA, Allen RP, Grauke JH, Brown JB, Rice ML, Hyde PR, Dement WC. RLS symptoms in primary care: A one year follow-up study. Sleep, 26(Suppl):A328, 2003.

Nichols DA, Kushida CA, Allen RP, Grauke JH, Brown JB, Rice ML, Hyde PR, Dement WC. Validation of RLS diagnostic questions in a primary care practice. Sleep, 26(Suppl):A346, 2003.

Nichols DA, Kushida CA, Allen RP, Hyde PR, Dement WC. Exploring RLS symptoms in two distinct primary care populations. Neurology, 60(5, Suppl 1):A38, 2003.

Kushida CA, Cardell CY, Buckley TM, Hyde PR, Dement WC. Effects of modafinil on PLMD-associated daytime sleepiness. Sleep, 25(Suppl):A67, 2002.

Friedman LF, Hernandez B, Mementhaler M, Mahapatra D, Kushida C, Yesavage JA. Morningness-eveningness in older insomniacs. Sleep, 25(Suppl):A365, 2002.

Hernandez B, Kushida CA, Friedman LF, Tu T, Wicks D, Yesavage J. Variability in home-administered bright light treatment. Sleep, 25(Suppl):A39, 2002.

Lu E, Friedman LF, Hernandez B, Tu T, Kushida C, Yesavage JA. Relationship between depression, anxiety and Epworth sleepiness scores with subjective and objective sleep measurements in elderly insomniacs. Sleep, 25(Suppl):A34, 2002.

Mahapatra D, Nichols DA, Kushida CA, Schillinger E, LeBaron S, Allen RP, Liu C, Tekwani S, Hyde PR, Dement WC. Restless legs syndrome in primary care: A validation study. Sleep, 25(Suppl):A491, 2002.

Nichols DA, Kushida CA, Allen RP, Grauke JH, Brown JB, Rice ML, Hyde PR, Dement WC. Treatment of RLS in primary care: Questionnaire-based measures. Sleep, 25(Suppl):A492, 2002.

Nichols DA, Kushida CA, Simon RD, Grauke JH, Brown JB, Hyde PR, Dement WC. Diagnosis of obstructive sleep apnea in a primary care population: Confirmation with polysomnography and ambulatory studies. Sleep, 25(Suppl):A226, 2002.

Clete A. Kushida, M.D., Ph.D., RPSGT 20

Nichols DA, Kushida CA, Allen RP, Grauke JH, Brown JB, Rice ML, Hyde PR, Dement WC. Confirmation of a high prevalence of restless legs syndrome in a primary care population. Sleep, 24(Suppl):A417, 2001.

Nichols DA, Kushida CA, Allen RP, Grauke JH, Brown JB, Rice ML, Hyde PR, Dement WC. Prevalence of restless legs syndrome in a primary care population. Neurology, 56(Suppl 3):A19, 2001.

Sarinas PS, Nguyen DA, Kalisetti D, Makhija M, Buadu EO, Chitkara RK, Kuschner WG, Benson K, Kushida CA. Risk of coronary artery disease in Veterans Affairs patients with sleep disordered breathing. Sleep, 24(Suppl):A290, 2001.

Tu TT, Hernandez B, Friedman LF, Kushida CA, Mahapatra D, Guilleminault C, Yesavage J. Major exclusion factors for elderly subjects in primary insomnia research studies. Sleep, 24(Suppl):A346, 2001.

Kushida CA, Poyares D, Colrain I, Sherrill C, Tu T, Gelber S, Hyde P, Dement WC. Subjective and objective measures of drowsiness in relation to sleep debt. Sleep, 23(Suppl 2):A247, 2000.

Guilleminault C, Pelayo R, Philip P, Karadeniz D, Kushida CA. First degree relatives of ALTE children. Sleep, 23(Suppl 2):A31, 2000.

Loewy D, Guilleminault C, Kushida C. Prediction of esophageal pressure elevations by crescendo snoring patterns. Sleep, 23(Suppl 2):A7, 2000.

Nichols DA, Kushida CA, Allen RP, Young T, Grauke JH, Brown JB, Hyde PR, Dement WC. Analysis of a primary care population with a high symptom-based prevalence of restless legs syndrome. Sleep, 23(Suppl 2):A389, 2000.

Nichols DA, Kushida CA, Simon RD, Young T, Grauke JH, Britzmann JB, Hyde PR, Dement WC. Use of ambulatory studies to confirm a high symptom-based prevalence of sleep apnea in a primary care population. Sleep, 23(Suppl 2):A388, 2000.

Roth T, Zammit G, Kushida C, Doghramji K, Mathias S, Buysee D. Use of the Global Sleep Assessment Questionnaire to identify patients with a sleep disorder. Sleep, 23(Suppl 2):A323, 2000.

Shukla RK, Kushida CA, Guilleminault C. Survey of the effects of alcohol on the sleep of college students. Sleep, 23(Suppl 2):A274, 2000.

Smith RS, Kushida CA. Risk of fatal occupational injury by time of day. Sleep, 23(Suppl 2):A110, 2000. Kushida CA, Edgar D, Hindman J, Seidel W, Palombini L, Abuazza GM, Hyde P, and Dement WC.

Pharmacologic-induced reduction of human sleep debt. Sleep, 22(Suppl):S118, 1999. Adornato BT, Li K, Murthy HHK, Kushida C, and Maung C. High frequency severe sleep apnea in non-

obese Asians: clinical and cephalometric observations. Neurology, 52(6, Suppl 2):A111, 1999. Chang A, Kushida C, Palombini L, Carrillo O, Hindman J, Hong S, Hyde P, and Guilleminault C.

Comparison study of actigraphic, polysomnographic, and subjective perception of sleep parameters. Sleep, 22(Suppl):S43, 1999.

Hindman JC, Kushida CA, Sherrill C, Jones J, and Hong SC. Sleep-disordered breathing detection by respiratory sound analysis. Sleep, 22(Suppl):S274, 1999.

Hsu S, Kushida CA, and Sherrill C. Acoustic pharyngometry and cervical position in obstructive sleep apnea patients. Sleep, 22(Suppl):S273, 1999.

Li KK, Kushida C, Adornato B, Maung C, Uritani N, Kram J, Riley R, and Powell N. Obstructive sleep apnea syndrome in the Asian population. Sleep, 22(Suppl):S104, 1999.

Li KK, Riley RW, Powell NB, Kushida C, Troell RJ. Obstructive sleep apnea syndrome (OSAS) in the Asian patient. Otolayng-Head Neck Surg, 121(2):127, 1999.

Maung CM, Kushida CA, van Derbur M, Jones J, Hsieh J, Laufer E, Hyde P, and Dement WC. Sleep complaints in incest survivors. Sleep, 22(Suppl):S203, 1999.

Murthy HH, Kushida CA, McKee A, Adornato BT, Dement WC, and Guilleminault C. Oromuscular correlates of patients with the obstructive sleep apnea syndrome. Sleep, 22(Suppl):S193, 1999.

Nichols DA, Kushida CA, Simon RD, Young T, Grauke JH, Britzmann JB, Hyde PR, and Dement WC. Symptom-based prevalence of sleep disorders in a primary care population. Sleep, 22(Suppl):S237, 1999.

Sherrill C, Kushida CA, Hong SC, Palombini L, Jones J, Hyde P, and Dement WC. Cervical positional effects on the obstructive sleep apnea syndrome. Sleep, 22(Suppl):S61, 1999.

Kushida CA, Guilleminault C, Mignot E, Hsieh J, O’Hara B, Clerk AA, Dement WC. Male twin concordance of craniofacial dysmorphism and obstructive sleep apnea. Sleep, 21(Suppl):141, 1998.

Kushida CA, Guilleminault C, Ahmed Jr. O, Clerk AA, and Dement WC. Reliability studies of the morphometric model for obstructive sleep apnea. Sleep Research, 26:405, 1997.

Clete A. Kushida, M.D., Ph.D., RPSGT 21

Kushida CA, Guilleminault C, Mignot O, Ahmed Jr. O, Hsieh J, O’Hara B, Clerk AA, and Dement WC. Familial patterns of craniofacial dysmorphism and obstructive sleep apnea. Sleep Research, 26:404, 1997.

Cho LD, Kushida CA, Guilleminault C, Clerk AA, and Dement WC. Upper airway resistance syndrome: Sleep stage thresholds from esophageal-pressure-related arousals. Sleep Research, 26:344, 1997.

Hsieh JY, Kushida CA, Guilleminault C, Clerk AA, and Dement WC. Obstructive sleep apnea patient survey on failure to return for treatment. Sleep Research, 26:377, 1997.

Kushida CA, Clerk AA, Giacomini A, Quinonez T, Lemons J, Mack A, and Guilleminault C. SleepLinkTM: An interactive linked computer program for sleep data analysis. Sleep Research, 25:507, 1996.

Kushida CA, Guilleminault C, Ahmed Jr. O, and Clerk AA. Clinical prediction of obstructive sleep apnea by a morphometric model. American Academy of Neurology Abstracts, Neurology, 46:A485, 1996.

Kushida CA, Guilleminault C, Ahmed Jr. O, and Clerk AA. Clinical prediction of obstructive sleep apnea by a morphometric model. Sleep Research, 25:274, 1996.

Kushida CA, Guilleminault C, Mignot E, Ahmed Jr. O, Won C, O'Hara B, and Clerk AA. Genetics and craniofacial dysmorphism in family studies of obstructive sleep apnea. Sleep Research, 25:275, 1996.

Kushida CA, Heller C, Kilduff TS, Baker TL, Dement WC, Guilleminault C, Mignot E, and Clerk AA. Autoradiographic analysis of narcoleptic canine brains following 14C-2-deoxyglucose administration during drug-induced cataplectic attacks. Sleep Research, 25:276, 1996.

Ahmed Jr. O, Kushida CA, Clerk AA, Oh CM, Springer EA, and Guilleminault C. Upper airway resistance syndrome: Patient characteristics. Sleep Research, 25:182, 1996.

Gadkary C, Kushida C, Clerk AA, and Guilleminault C. Daytime sleepiness measured by the Epworth sleepiness scale and the multiple sleep latency test in patients with sleep disorders. American Academy of Neurology Abstracts, Neurology, 46:A485, 1996.

Oh CM, Kushida CA, Guilleminault C, Springer EA, Ahmed Jr. O, and Clerk AA. Upper airway resistance syndrome: Relationship to menopausal status. Sleep Research, 25:322, 1996.

Springer EA, Kushida CA, Guilleminault C, Ahmed Jr. O, Oh CM, Black JE, and Clerk AA. Upper airway resistance syndrome: polysomnographic characteristics. Sleep Research, 25:373, 1996.

Kushida CA, Guilleminault C, Ahmed Jr. O, and Clerk AA. A predictive morphometric model for obstructive sleep apnea. Sleep Research, 24:269, 1995.

Kushida CA, Guilleminault C, Mignot E, O'Hara B, and Clerk AA. Genetic patterns in craniofacial dysmorphism of obstructive sleep apnea patients. Sleep Research, 24:270, 1995.

Kushida CA, Zoltoski RK, and Gillin JC. Expression of m2 muscarinic receptor mRNA in rat brain with REM sleep deprivation. Sleep Research, 24:37, 1995.

Kushida CA, Zoltoski RK, and Gillin JC. Expression of m3 muscarinic receptor mRNA in rat brain with REM sleep deprivation. Sleep Research, 23:13, 1994.

Kushida CA, Zoltoski RK, Yang A, and Gillin JC. Expression of m1 muscarinic receptor mRNA in rat brain with REM sleep deprivation. Sleep Research, 22:31, 1993.

Shaw P, Kushida CA, and Rechtschaffen A. Hypothermia is probably not the proximal cause of death in sleep deprived rats. Sleep Research, 22:345, 1993.

Kushida C. The effects of chronic REM sleep deprivation in the rat. Abstracts: JABSOM Biomedical Sciences Symposium, Honolulu, Hawaii, 10:25, 1990.

Rechtschaffen A, Bergmann BM, Everson CA, Kushida CA, and Gilliland MA. Sleep deprivation in the rat. Abstracts: One Hundred Fifty-fifth National Meeting of the American Association for the Advancement of Science, San Francisco, California, January 14-19, 1989.

Kushida CA, Mesh CL, Gewertz BL, Fang VS, Refetoff S, Bergmann BM, and Rechtschaffen A. Intestinal metabolic rate following blood infusion from sleep deprived rats. Sleep Research, 17:316, 1988.

Mesh CL, Kushida C, Gewertz BL, Bergmann BM, and Rechtschaffen A. Paradoxic response of splanchnic circulation to blood from sleep deprived animals. Federation of American Societies for Experimental Biology (FASEB) Journal, 2(4):A741, 1988.

Kushida C. The effects of chronic paradoxical sleep deprivation in the rat. Abstracts: First Annual Graduate Student Symposium of the Program for Biological Approaches to Behavior, Chicago, Illinois, 1:11, 1987.

Everson CA, Kushida CA, Bergmann BM, Gilliland MA, Pilcher JJ, Fang VS, and Rechtschaffen A. Recovery from chronic sleep deprivation in the rat. Sleep Research, 16:521, 1987.

Kushida C, Bergmann B, Fang VS, Leitch CA, Obermeyer W, Refetoff S, Schoeller DA, and Rechtschaffen A. Physiological and biochemical effects of paradoxical sleep deprivation in the rat. Sleep Research, 15:219, 1986.

Clete A. Kushida, M.D., Ph.D., RPSGT 22

Benca RM, Everson C, Kushida C, Bergmann B, and Rechtschaffen A. Effects of sleep deprivation on immune function in rats. Sleep Research, 15:211, 1986.

Bergmann B, Fang VS, Kushida C, Everson C, and Rechtschaffen A. Hypothalamic-adrenal variables in paradoxical and total sleep deprivation of rats. Sleep Research, 15:212, 1986.

Everson C, Kushida C, Suthipinittharm P, Kiela J, Soltani K, Bergmann B, and Rechtschaffen A. Skin changes in sleep deprived rats. Sleep Research, 15:217, 1986.

Schoeller DA, Kushida C, Everson C, Leitch CA, Bergmann B, and Rechtschaffen A. Energy expenditure of sleep deprived rats measured with doubly labeled water. Federation Proceedings, 46(3):751, 1986.

Suthipinittharm P, Everson C, Kushida C, Kiela J, Bergmann BM, Soltani K, and Rechtschaffen A. Pathologic and immunopathologic studies of skin lesions in sleep-deprived rats. Abstracts: Seventh Regional Conference of Dermatology: Asian-Australasian. Bangkok, Thailand, 7:42, 1986.

Kushida C, Bergmann B, Everson C, Winter J, and Rechtschaffen A. Paradoxical sleep deprivation in the rat: I. Physiological effects. Sleep Research, 13:191, 1984.

Bergmann B, Kushida C, Hennessy C, Winter J, and Rechtschaffen A. Paradoxical sleep deprivation in the rat: II. Energy consumption. Sleep Research, 13:185, 1984.

Kushida C, Baker T, and Dement W. Spontaneous and drug-induced cataplexy in narcoleptic Doberman pinschers. Abstracts: Sixth Ann Biol Sci Undergraduate Research Conf, Santa Clara, California, 6:2, 1981.

GRANTS (see Attachment 1)

SERVICE TO STANFORD UNIVERSITY

Leadership Roles

2012-curr Chair, Likelihood to Recommend Task Force, Stanford Sleep Medicine Center 2010-curr Medical Director, Stanford Sleep Medicine Center 2008-curr Chair, Clinical Research Committee, Stanford Sleep Medicine Center 2008-curr Chair, Stanford Sleep Medicine Center Faculty Committee 2008-2010 Acting Medical Director, Stanford Sleep Medicine Center 2008-2009 Participant, Stanford Leadership Development Program 2007-2008 Chair/Organizer, Stanford Sleep Center Grand Rounds for 2007-08 academic year 2007-2008 Chair, Search Committee, Stanford Sleep Medicine Faculty 1996-curr Director, Center for Human Sleep Research 1996-curr Associate Director of Research, Stanford Sleep Medicine Center 1980-1981 Chair, Academic Organizations Board, Stanford University 1980-1982 Resident Assistant (R.A.), Stanford University Committee Service

2011-curr Member, Awards Nominating Committee, Department of Psychiatry and Behavioral Sciences 2010-curr Member, Academic Progress and Promotions Committee, Department of Psychiatry and

Behavioral Sciences 2010-curr Member, Division of Sleep Medicine Steering Committee 2010-curr Member, Clinical Performance Team 4, Stanford Hospital and Clinics 2010-curr Member, Sleep Division UTL/MCL Search Committee 2010-curr Member, Center for Sleep Sciences and Medicine Division Informatics Team Task Force 2010-2011 Member, Sleep Medicine Center Epic Subteam 2010 Member, Website Committee, Stanford Sleep Medicine Center 2010 Member, Sleep Medicine Center Scheduling Committee, Stanford Medicine Outpatient Center 2009-curr Member, Executive Committee, Stanford Medicine Outpatient Center 2009 Member and Physician Champion, EPIC Committee, Stanford Sleep Medicine Center 2009 Member, Outpatient Physicians for Best Practices Group 2009 Interviewer, Candidates for Chair of the Department of Psychiatry and Behavioral Sciences 2008-2009 Member, Quality Assurance and Improvement for Psychiatry Professional Practice Evaluation

Committee (PPEC), Department of Psychiatry and Behavioral Sciences 2008- curr Member, Clinical Executive Committee, Department of Psychiatry and Behavioral Sciences 2008- curr Member, Clinic Chiefs, Stanford University Medical Center 2008- curr Member, Operations Committee, Stanford Sleep Medicine Center

Clete A. Kushida, M.D., Ph.D., RPSGT 23

2008- curr Member, Polysomnography Inter-rater Reliability Committee, Stanford Sleep Medicine Center 2008- curr Member, Polysomnographic Scoring Standardization and Implementation Committee,

Stanford Sleep Medicine Center 2008-2009 Member, Operations Planning Executive Steering Committee, Stanford Medicine Outpatient

Center 2003 Member, Search Committee, Stanford University Sleep and Circadian Neurobiology

Laboratory Director 2001-2002 Reviewer, Medical School Applications, Stanford University Medical School Admissions

Committee 1997 Member, Stanford University Health and Safety Committee

Other

2013 Interviewee, Stanford Human Research Protection Program (HRPP) Site Visit by the Association for Accreditation of Human Research Protection Programs (AAHRPP), October 21, 2013.

SERVICE TO ACADEMIC AND OTHER ORGANIZATIONS

Leadership Roles

2013-curr Chair, Research Committee, American Sleep Medicine Foundation (ASMF) 2013 Chair, American Sleep Medicine Foundation (ASMF) Bridge to K Research Award Review

Panel 2011-curr President, World Sleep Federation 2011-curr Chair, International Informatics Users’ Group, World Sleep Federation 2011-curr Chair, International Sleep Specialist and Technician Training Forum, World Sleep Federation 2011 Chair, AHRQ Electronic Data Methods Forum Data Governance Manuscript Review Panel 2011 Chair, Future of Sleep Medicine Outcomes and Registries Task Force, American Academy of

Sleep Medicine 2010-2013 Chair, Data Governance Committee, AHRQ Electronic Data Methods Forum 2010-2013 Chair, Administrative Team, AHRQ-supported Comparative Outcomes Management with

Electronic Data Technology (COMET) Study 2010-2013 Chair, Steering Committee, AHRQ-supported Comparative Outcomes Management with

Electronic Data Technology (COMET) Study 2010-2013 Chair, Ontology Task Force, AHRQ-supported Comparative Outcomes Management with

Electronic Data Technology (COMET) Study 2010-2011 Immediate Past President, California Sleep Society 2010-2011 President, Associated Professional Sleep Societies Board of Directors 2009-2010 President, American Academy of Sleep Medicine 2009-2010 Chair, Executive Committee, American Academy of Sleep Medicine 2008-2010 Founding/Inaugural President, California Sleep Society 2008-2011 Chair, International Sleep Medicine Board Certification for Sleep Specialists Program 2008-curr Chair, Data and Safety Monitoring Board, Motivating Adherence to CPAP in Obstructive Sleep

Apnea (NHLBI HL67209, PI: Mark Aloia, Ph.D.) 2007-2009 Board of Directors Liaison, Academic Affairs Committee, American Academy of Sleep

Medicine 2006-2008 Secretary-Treasurer, American Board of Sleep Medicine 2006-2008 Secretary, American Sleep Medicine Foundation 2006-2011 Principal Investigator, Apnea Positive Pressure Long-term Efficacy Study (APPLES), National

Heart Lung Blood Institute (NHLBI HL68060-6) 2006-2008 Secretary-Treasurer, American Academy of Sleep Medicine 2006-2007 Chair, Presidential Committee on Sleep Education in Medical Schools, American Academy of

Sleep Medicine 2005-2008 Board of Directors Liaison, Standards of Practice Committee, American Academy of Sleep

Medicine 2003-2005 Chair, Standards of Practice Committee, American Academy of Sleep Medicine 2002-curr Chair, Publications and Presentations Committee, Apnea Positive Pressure Long-term

Efficacy Study (APPLES), National Heart Lung Blood Institute (NHLBI)

Clete A. Kushida, M.D., Ph.D., RPSGT 24

2002-curr Chair, Steering Committee, Apnea Positive Pressure Long-term Efficacy Study (APPLES), National Heart Lung Blood Institute (NHLBI)

2002-2006 Project Director, Apnea Positive Pressure Long-term Efficacy Study (APPLES), National Heart Lung Blood Institute (NHLBI)

2002-2003 Vice-Chair, Standards of Practice Committee, American Academy of Sleep Medicine 2000-2006 Co-Chair, Part II Certification Exam, American Board of Sleep Medicine 1996-2002 Project Director, National Primary Care Education and Training Project 1996 Founder, Somnet Systems, Incorporated, Los Altos Hills, California 1981-1982 Founder and President, Biotech Scientific Instruments, Santa Clara, California Board and Committee Service

2013-curr Member, World Sleep Federation-World Association of Sleep Medicine Organizing Committee

2013-curr World Health Organization (WHO) Sleep Medicine Content Development Panel for the International Classification of Diseases 11th edition (ICD-11)

2013-curr Member American Academy of Sleep Medicine-Sleep Research Society Joint Task Force 2013-curr Electronic Data Technology (EDM) Forum Steering Committee 2012-curr Reviewer, American Sleep Medicine Foundation (ASMF) Humanitarian Projects Award 2012 Reviewer, NIH, Common Fund initiative, NIH Health Care Systems Research Collaboratory -

Pragmatic Clinical Trials Demonstration Projects 2011-curr Member, Executive Committee, World Sleep Federation 2011-curr Member, Palmetto GBA California/Nevada Contractor Advisory Committee 2011-curr Member, American Academy of Dental Sleep Medicine, ORANGE Oral Appliance Registry

Development Task Force 2013 Co-Chair, American Sleep Medicine Foundation (ASMF) Educational Projects Award Review

Panel 2011 Reviewer, NIH, Special Emphasis Panel, Mechanisms of Excitability, Pain and Infection in the

Central Nervous System, Brain Disorders and Clinical Neuroscience Integrated Review Group 2011 Reviewer, NIH, Acute Neural Injury and Epilepsy (ANIE) study section, Brain Disorders and

Clinical Neuroscience Integrated Review Group (10/20/11) 2011 Member, Presidential Task Force to Review the ASMF Grant Portfolio, American Sleep

Medicine Foundation (ASMF) 2011 Reviewer, American Sleep Medicine Foundation (ASMF) Humanitarian Projects Award 2011 Reviewer, NIH, Acute Neural Injury and Epilepsy (ANIE) study section, Brain Disorders and

Clinical Neuroscience Integrated Review Group (1/19/11) 2010-curr Member, Informatics Team, AHRQ-supported Comparative Outcomes Management with

Electronic Data Technology (COMET) Study 2010-2013 Member, Research Team, AHRQ Electronic Data Management Forum 2010-2013 Member, Steering Committee, AHRQ Electronic Data Management Forum 2010-curr Member, Clinical Subgroup, Academic Alliance for Sleep Research 2010-2011 Member, Task Force to Revise Operations of the Standards of Practice Committee, American

Academy of Sleep Medicine 2010 Reviewer, NIH Small Business Respiratory Sciences Special Emphasis Panel 2010 Reviewer, Hong Kong Research Grants Council General Research Fund 2009 Reviewer, NIH Challenge and Grand Opportunities Grant Applications 2008-2011 Member, Board of Directors, California Sleep Society 2008-2011 Member, Legislative Affairs Committee, California Sleep Society 2008-2011 Member, Nominating Committee, California Sleep Society 2008-curr Member, Governing Council, World Sleep Federation 2008-curr Member, Obstructive Sleep Apnea Working Group, Academic Alliance for Sleep Research 2008-curr Member, Academic Alliance for Sleep Research (Stanford University, Harvard University,

University of Pennsylvania, University of Wisconsin) 2008-2011 Member, Board of Directors, Associated Professional Sleep Societies 2008-2010 Member, Board of Directors Guidelines Task Force, American Academy of Sleep Medicine 2008-2010 Member, Nominating Committee, American Academy of Sleep Medicine 2008-2009 Member, Presidential Task Force to Examine the Nominating Process, American Academy of

Sleep Medicine

Clete A. Kushida, M.D., Ph.D., RPSGT 25

2008 Member, NIH National Heart, Lung, and Blood Institute (NHLBI) Respiratory Medicine Related Research Training for Adult and Pediatric Fellows Working Group

2008 Dissertation Reviewer, Candidate for Doctor of Philosophy, The Hong Kong Polytechnic University

2007-2010 Member, Committee on Committees, Board of Directors, American Academy of Sleep Medicine

2007 Dissertation Reviewer, Candidate for Doctor of Philosophy in Medicine, University of Sydney, Australia

2007 Facilitator, Thematic Poster Session, Diagnosis and Clinical Consequences of Sleep Disorders Breathing, American Thoracic Society 2007 International Conference, San Francisco, CA, May 22, 2007.

2006-2010 Member, Executive Committee, Board of Directors, American Academy of Sleep Medicine 2005-2010 Member, Board of Directors, American Sleep Medicine Foundation 2005-2010 Member, Board of Directors, American Academy of Sleep Medicine 2005-2007 Site Visitor, Committee on Accreditation for Polysomnography (CoAPSG) 2005-2007 Member, Committee on Accreditation for Polysomnography (CoAPSG) 2004-2007 Member, Standards of Practice Liaison for Movement Disorders and Digital Analysis sections

of the New Scoring Manual of Sleep 2003-2009 Member, Medical Advisory Board, Restless Legs Syndrome Foundation 2003 Member, American Academy of Sleep Medicine Presidential Committee for Development of

New Scoring Manual of Sleep 2003 Consultant, The Council of Healthcare Advisors 2002-2006 Member, Appeals Committee, Board of Directors, American Board of Sleep Medicine 2002-2006 Member, Nominating Committee, Board of Directors, American Board of Sleep Medicine 2002 Consultant, MedaCorp 2002 Member, Accreditation Council for Graduate Medical Education (ACGME) Ad Hoc

Interdisciplinary Committee on Sleep Medicine 2001-2011 Member, Executive Committee, Board of Directors, American Board of Sleep Medicine 2001-2005 Member and Rotating Chair, Restless Legs Syndrome National Advisory Board,

GlaxoSmithKline 2001-2005 Member, Global Medical Advisory Board, Pharmacia Corporation 2001 Member, Pickwick Dinner Steering Committee, National Sleep Foundation 2001 Reviewer, Pickwick Fellowship Applications Committee, National Sleep Foundation 2001 Medical Consultant, Nikken Corporation 2000-2010 Member, Board of Directors, American Board of Sleep Medicine 1998-2000 Member, Medical Advisory Board, Life Sleep Systems, Incorporated 1999-2005 Member, Standards of Practice Committee, American Academy of Sleep Medicine 1998-2000 Site Accreditation Visitor, American Academy of Sleep Medicine 1997-2006 Board Examiner, American Board of Sleep Medicine 1997-1999 Member, Restless Legs Syndrome Task Force, Standards of Practice Committee, American

Academy of Sleep Medicine 1997 Member, Institutional Review Board, Clinical Monitoring Center, Palo Alto, California 1995 Member, Trainee Day Committee, Associated Professional Sleep Societies Meeting 1987-1988 Sophomore Representative, Dean's Committee, Univ. of Chicago Pritzker School of Medicine 1987-1988 Member, Medical Student Activities Finance Committee, U of Chicago Pritzker School of

Medicine 1996 Member, Sleep Research Society Annual National High School Essay Contest Judging

Committee 1996 Discussant, American Academy of Neurology Focus Group on Long-Range Activities 1988-1990 Member, National Task Force on Medical School Curricula, Associated Professional Sleep

Societies 1987-1988 University of Chicago Representative, Organization of Student Representatives, AAMC Membership

2009-curr California Medical Association 2008-curr California Sleep Society (CSS) 1996-curr American Association of Sleep Technologists (AAST) 1995-curr American Academy of Sleep Medicine (AASM)

Clete A. Kushida, M.D., Ph.D., RPSGT 26

1994-curr American Academy of Neurology Section on Sleep 1992-curr American Academy of Neurology (AAN) 1986-1991 Physicians for Social Responsibility (PSR) 1985-1992 American Medical Association (AMA) 1983-1986 Society for Neuroscience 1981-curr Sleep Research Society (SRS)

SERVICE TO ACADEMIC JOURNALS AND OTHER PUBLICATIONS

2015-curr Editor-in-Chief, Sleep Science and Medicine Journal, BioMed Central 2012-curr Member, Advisory Board, Sleep and Biological Rhythms Journal 2012-curr Member, Editorial Board, Sleep Medicine Reviews Journal 2012-curr Senior Editor, e-GEMS (electronic publications Generating Evidence and MethodS (to

improve patient outcomes), Electronic Data Methods (EDM) Forum 2011-curr Associate Editor, Journal SLEEP 2011-curr Member, Editorial Board, European Neurological Journal 2010-curr Associate Editor, Frontiers in Sleep and Chronobiology 2010 Member, Editorial Board, Sleep Medicine Research 2008-2009 External Reviewer, Sleep and Health Education Program Website, Division of Sleep

Medicine, Harvard Medical School 2004-curr Member, Editorial Board, Journal of Clinical Sleep Medicine 2003-curr Member, Editorial Board, Journal SLEEP 2000 Advisor, Sleep Disorders Text Revision Work Group of DSM-IV 1995-curr Consulting reviewer for journals Anesthesiology, J Biological Rhythms, BioMedCentral

(Musculoskeletal Disorders), Chest, J General Internal Medicine, J Psychiatric Research, Neurology, New England Journal of Medicine, Patient Care, Physiology and Behavior, Sleep, Sleep Medicine, and Sleep Research Online

1999-2001 Associate Editor and Member, Clinical Development Team, MDVista.com 1996-curr Reviewer, Associated Professional Sleep Society Meeting Abstracts

SERVICE TO THE COMMUNITY

2011 Volunteer, Stanford Residential and Dining Enterprises Wellness Fair 2010 Volunteer, Stanford Residential and Dining Enterprises Wellness Fair 2009 Volunteer Consultant, “The Biggest Loser” Television Show 2009 Volunteer, Senior Games, Stanford University 2003-2005 Volunteer Teacher, Stanford Medical Youth In Science Program 1980-1982 Member, Phi Kappa Psi Fraternity, Stanford University 1976 Member, National Eagle Scout Association

INTELLECTUAL PROPERTY

2010 Apnea Treatment Method and Device (Patent #12,771,679) 2001 Morphometric Modeling System and Method (Patent #6,213,959) 2000 Morphometric Measurement Tool (Patent #6,048,322) 1997 SleepLinkTM: An Interactive Linked Computer Program for Sleep Data Analysis

ORAL PRESENTATIONS

Peer-Reviewed Presentations at International, National, State, and Regional Meetings

“CPAP and oral appliance therapy? Which is better?” Speaker, Postgraduate Course, Twenty-Eighth Annual Meeting of the Associated Professional Sleep Societies, Minneapolis, MN, June 30, 2014.

“Sleep-related respiratory disorders in neurological diseases: An update.” Speaker, 2014 American Academy of Neurology Annual Meeting, Philadelphia, PA, April 28, 2014.

“What have large trials taught us about treating obstructive sleep apnea.” Speaker, Eighteenth Annual Advances in Diagnosis and Treatment of Sleep Apnea and Snoring, San Francisco, CA, February 15, 2014.

“Movement disorders in sleep.” Speaker, The Sixth Educational Meeting of the California Sleep Society, Burlingame, CA, October 13, 2013.

Clete A. Kushida, M.D., Ph.D., RPSGT 27

“What have we learned from large-scale multicenter national and international research studies on obstructive sleep apnea? Chair, Discussion Group Session, Twenty-Seventh Annual Meeting of the Associated Professional Sleep Societies, Baltimore, MD, June 3, 2013.

“Sleep related movement disorders.” Speaker, The Fifth Educational Meeting of the California Sleep Society, Los Angeles, CA, October 6, 2012.

“Evaluation of a new pediatric positive airway pressure mask.” Speaker, Oral Presentation, Twenty-Sixth Annual Meeting of the Associated Professional Sleep Societies, Boston, MA, June 11, 2012.

“An unusual parasomnia case.” 34th Annual Meeting of the American Association of Sleep Technologists, Boston, MA, June 10, 2012.

“Spectrum of neurocognitive disorders in OSAS in adults.” Speaker, Hypoxia and Neurocognitive Impairment: Lessons From Sleep Apnea and Ischemic Brain Injury, ATS (American Thoracic Society) 2012 International Conference, San Francisco, CA, May 22, 2012.

“The intersections between informatics and comparative effectiveness research in sleep medicine.” Speaker, Oral Session, The Evolving World of Sleep in the Information Age: Tools and Approaches for Improving Sleep Data Management, Clinical Care, and Research, Twenty-Fifth Anniversary Meeting of the Associated Professional Sleep Societies, Minneapolis, MN, June 15, 2011.

“Outcomes and registries.” Speaker, Discussion Group, The Future of Sleep Medicine, Twenty-Fifth Anniversary Meeting of the Associated Professional Sleep Societies, Minneapolis, MN, June 15, 2011.

“Pharmacologic treatment concerns in patients with hypersomnia." Chair, Oral Presentation Session, Twenty-Fifth Anniversary Meeting of the Associated Professional Sleep Societies, Minneapolis, MN, June 14, 2011.

“Challenging narcolepsy case.” Speaker, Postgraduate Course, Case-based Review of Sleep Disorders: Patient Pearls, Thirty-Third Annual Meeting of the American Association of Sleep Technologists, Minneapolis, MN, June 12, 2011.

“Introduction to sleep EEG/polysomnography.” Speaker, Sleep Research Society Sixteenth Annual Trainee Symposia Series, Twenty-Fifth Anniversary Meeting of the Associated Professional Sleep Societies, Minneapolis, MN, June 12, 2011.

“Apnea Positive Pressure Long-term Efficacy Study (APPLES).” Speaker, Sleep Apnea Treatment Trials, ATS (American Thoracic Society) 2011 International Conference, Denver, CO, May 15, 2011.

“Recognition and diagnosis of primary sleep disorders”, “Pathophysiology, risk factors, comorbidities, and differential diagnoses of primary sleep disorders”, and “Treatment of primary sleep disorders.” 2011 Annual Northern California Kaiser Permanente Psychiatry and Chemical Dependency Conference, San Francisco, CA, April 30, 2011.

“Neurocognitive function and obstructive sleep apnea: The Apnea Positive Pressure Long-term Efficacy Study (APPLES).” Current Topics in Sleep Medicine, American Academy of Sleep Medicine, San Diego, CA, February 29, 2011.

“Sleep related movement disorders.” Speaker, The Third Educational Meeting of the California Sleep Society, Los Angeles, CA, October 9, 2010.

“The role of sleep in medication overuse headache.” Speaker, Third Annual Fall Conference, Headache Cooperative of the Pacific, Carlsbad, CA, September 25, 2010.

“Year-in-review: Sleep apnea.” Speaker, Oral Presentation, Twenty-Fourth Annual Meeting of the Associated Professional Sleep Societies, San Antonio, TX, June 6, 2010.

“Central nervous system hypersomnias.” Speaker, Oral Presentation, Twenty-Fourth Annual Meeting of the Associated Professional Sleep Societies, San Antonio, TX, June 5, 2010.

“Sleep related movement disorders.” Speaker, The Second Educational Meeting of the California Sleep Society, Burlingame, CA, November 14, 2009.

“Sleep apnea and hypertension: A clinical perspective.” Speaker, Oral Presentation, Twenty-Third Annual Meeting of the Associated Professional Sleep Societies, Seattle, WA, June 11, 2009.

“Ethical challenges in obstructive sleep apnea treatment trials.” Speaker, Discussion Group Session, Twenty-Third Annual Meeting of the Associated Professional Sleep Societies, Seattle, WA, June 10, 2009.

“Restless legs syndrome.” Speaker, “The Interface of Sleep and Neurology” Postgraduate Course, Thirty-First Annual Meeting of the Associated Professional Sleep Societies, Seattle, WA, June 7, 2009.

“Sleep related movement disorders.” Speaker, The Inaugural Educational Meeting of the California Sleep Society, La Jolla, CA, November 22, 2008.

“Narcolepsy and other hypersomnias.” Speaker, Board Review for Sleep Specialists Course, Reston, VA, September 27, 2008.

Clete A. Kushida, M.D., Ph.D., RPSGT 28

“Apnea positive pressure long-term efficacy cardiovascular outcomes research study (APPLE CORS): Preliminary study.” Speaker, Oral Presentation, Twenty-Second Annual Meeting of the Associated Professional Sleep Societies, Baltimore, MD, June 12, 2008.

“Sleep apnea and learning.” Speaker, Memory and Learning, National Sleep Foundation CME Symposium, Baltimore, MD, June 9, 2008.

“Hypersomnia of CNS origin” Speaker, “The Interface of Sleep and Neurology” Postgraduate Course, Twenty-Second Annual Meeting of the Associated Professional Sleep Societies, Baltimore, MD, June 8, 2008.

“Controversies and alternatives in the management of patients with complicated cases of sleep related breathing disorders.” Chair, Discussion Group Session, Twenty-Second Annual Meeting of the Associated Professional Sleep Societies, Baltimore, MD, June 8, 2008.

“Narcolepsy and other hypersomnias.” Speaker, “The Interface of Sleep and Neurology” Postgraduate Course, Twenty-Second Annual Meeting of the Associated Professional Sleep Societies, Baltimore, MD, June 8, 2008.

“A randomized, double-blind, placebo-controlled study to assess the efficacy and tolerability of XP13512 1200 mg in patients with restless legs syndrome.” Speaker, Oral Presentation, Sixtieth Annual Meeting of the American Academy of Neurology, Chicago, IL, April 17, 2008.

“Narcolepsy with or without cataplexy” and “Narcolepsy and other hypersomnias and seizures.” Speaker, Board Review for Sleep Specialists Course, Marina del Rey, CA, October 12-14, 2007.

“Narcolepsy with or without cataplexy”, “Hypersomnias other than narcolepsy”, “Sleep and neurodegenerative disorders”, and “Narcolepsy and other hypersomnias and seizures.” Speaker, Board Review for Sleep Specialists Course, Chicago, IL, September 21-23, 2007.

“Pramipexole did not induce orthostatic hypotension or affect blood pressure or pulse in patients with restless legs syndrome.” Speaker, 11th European Federation of Neurological Societies Congress, Brussels, Belgium, August 26, 2007.

“Comprehensive OSA management: Current practice, controversies, and future directions.” Chair, Discussion Group Session, Twenty-First Annual Meeting of the Associated Professional Sleep Societies, Minneapolis, MN, June 13, 2007.

“Management of primary RLS” and “RLS and sleep apnea.” Speaker, Restless Legs Syndrome: Different Profiles, Different Approaches, CME Interactive Dinner Symposium, Minneapolis, MN, June 12, 2007.

“Approach to narcolepsy and other hypersomnias.” Speaker, “Best Practices in Sleep Medicine 2007” Postgraduate Course at the Twenty-First Annual Meeting of the Associated Professional Sleep Societies, Minneapolis MN, June 9, 2007.

“Update on CPAP and other behavioral therapies.” Speaker, “Multidisciplinary Treatment of OSA” Postgraduate Course at the Twenty-First Annual Meeting of the Associated Professional Sleep Societies, Minneapolis MN, June 9, 2007.

“Rationale, design, demographics, and screening.” Speaker, “Apnea positive pressure long-term efficacy study (APPLES)” Division of Lung Diseases/National Heart, Lung, and Blood Institute Symposium, American Thoracic Society 2007 International Conference, San Francisco, CA, May 21, 2007.

“Diagnostic testing in sleep disorders: Actigraphy, MSLT, and MWT.” Speaker, Postgraduate Course, “Non-Pulmonary Sleep Medicine for the Pulmonary Physician”, American Thoracic Society 2007 International Conference, San Francisco, CA, May 18, 2007.

“XP13512 treatment of RLS.” Speaker, Pain and the Sensory Symptoms of RLS Symposium, World Association of Sleep Medicine (WASM) Second World Congress 2007, Bangkok, Thailand, February 7, 2007.

“Narcolepsy with and without cataplexy” and “Narcolepsy and other hypersomnias and seizures: Case-based breakout session.” Speaker, Board Review for Sleep Specialists Course, Chicago, IL, October 7-8, 2006.

“XP13512 improves symptoms and sleep disturbance in RLS patients: Results of a 2-week, randomized, double-blind, placebo-controlled, cross-over polysomnography trial.” Speaker, Oral Presentation at the Twentieth Annual Meeting of the Associated Professional Sleep Societies, Salt Lake City, UT, June 21, 2006.

“Twenty-five years of positive pressure therapy: What have we learned?” Chair, Discussion Group Session, Twentieth Annual Meeting of the Associated Professional Sleep Societies, Salt Lake City, UT, June 20, 2006.

“Current therapeutic and management strategies in restless legs syndrome.” Speaker, “What the Psychiatrist Needs to Know About Sleep-related Movement Disorders”, CME Symposium, 159th Annual Meeting of the American Psychiatric Association, Toronto, CN, May 25, 2006.

Clete A. Kushida, M.D., Ph.D., RPSGT 29

“XP13512 is well-tolerated and effective in treating moderate to severe RLS in a 2-week, randomized, double-blind, placebo-controlled exploratory trial.” Speaker, Platform Session: Sleep Disorders, Fifty-eighth Annual Meeting of the American Academy of Neurology, San Diego, CA, April 2, 2006.

“The neuropsychiatry of sleep and its disorders.” Chair, Oral Presentation Session and Presenter, “Restless legs syndrome and periodic limb movements in sleep.” Seventeenth Annual Meeting of the American Neuropsychiatric Association, San Diego, CA, February 21, 2006.

“Evidenced-based medicine and standard setting in health care delivery.” Speaker, Management of a Sleep Disorders Center: Administrative, Legal and Health Policy Practices Course, American Academy of Sleep Medicine, San Diego, CA, February 12, 2006.

“Challenges in clinical trials for sleep apnea.” Chair, Discussion Group Session, Nineteenth Annual Meeting of the Associated Professional Sleep Societies, Denver, CO, June 21, 2005.

“Up-to-date diagnosis and strategy of therapy for sleep apnea syndrome in USA.” Speaker, The 45th Annual Meeting of the Japanese Respiratory Society, Chiba, Japan, April 14, 2005.

“Clinical trials for sleep-disordered breathing: Palo Alto experience.” Speaker, Ninth International Symposium on Sleep and Breathing, Newport, Rhode Island, October 16, 2004.

“The use of esophageal manometry in the diagnosis of sleep-related breathing disorders.” Speaker, 26th Annual International Conference of the Institute of Electrical and Electronics Engineers (IEEE) Engineering in Medicine and Biology Society, San Francisco, CA, September 3, 2004.

“Evidence-based medicine tools and techniques for the sleep clinician or researcher.” Chair and Speaker, Postgraduate Course at the Eighteenth Annual Meeting of the Associated Professional Sleep Societies, Philadelphia, PA, June 6, 2004.

“Epidemiology and risk factors for RLS.” Speaker, Postgraduate Course at the Eighteenth Annual Meeting of the Associated Professional Sleep Societies, Philadelphia, PA, June 5, 2004.

“Apnea positive pressure long-term efficacy study.” Chair, Discussion Group Session, Seventeenth Annual Meeting of the Associated Professional Sleep Societies, Chicago, IL, June 6, 2003.

“New developments and treatment of periodic limb movement disorder.” “Diagnostic and treatment strategies for sleepwalking.” Speaker, Beyond “Pulmonary” Sleep Medicine Postgraduate Course, American College of Chest Physicians Annual Meeting, San Diego, CA, November 2, 2002.

“Effects of modafinil on PLMD-associated daytime sleepiness.” Speaker, Sixteenth Annual Meeting of the Associated Professional Sleep Societies, Seattle, WA, June 2002.

“Interventions for sleep disturbances in Alzheimer’s patients.” Speaker, Fourth Annual Conference, Updates on Dementia: Translating Research Into Practice, Stanford University School of Medicine, Stanford, CA, March 13, 2002.

“Esophageal manometry in the diagnosis of sleep-related breathing disorders.” Speaker, Postgraduate Course at the Fifteenth Annual Meeting of the Associated Professional Sleep Societies, Chicago, IL, June 2001.

“Management and operation of a sleep lab” and “Diagnosis and treatment strategies for OSA.” Speaker, Joint Seminar on Sleep Disorders of the Psychology Society and Thoracic Society of Japan, Nagoya, Japan, October 2, 1999.

“Screening and case findings for sleep apnea." Chair, Oral Presentation Session, Thirteenth Annual Meeting of the Associated Professional Sleep Societies, Orlando, FL, June 1999.

“Pharmacologic-induced reduction of human sleep debt.” Speaker, Oral Presentation, Thirteenth Annual Meeting of the Associated Professional Sleep Societies, Orlando, FL, June 22, 1999.

“Developmental and ethnic factors in the obstructive sleep apnea syndrome.” Speaker, Meet the Professor Session, Thirteenth Annual Meeting of the Associated Professional Sleep Societies, Orlando, FL, June 22, 1999.

“Male twin concordance of craniofacial dysmorphism and obstructive sleep apnea.” Speaker, Oral Presentation, Twelfth Annual Meeting of the Associated Professional Sleep Societies, New Orleans, LA, June 22, 1998.

“Primary care: The frontline of sleep medicine in the new millennium.” Speaker, Discussion Group Session with R. Simon, T. Young, and W. Dement, Twelfth Annual Meeting of the Associated Professional Sleep Societies, New Orleans, LA, June 1998.

“Evaluation of the sleepy patient” and “Medical management of OSA.” Speaker, “Obesity and Sleep Apnea (OSA): A Multidisciplinary Approach to Management Conference”, The Fortieth Annual Clinic Day, Saint Joseph Mercy-Oakland, Pontiac, MI, November 12, 1997.

“New technology in sleep medicine II.” Chair, Discussion Group Session, Eleventh Annual Meeting of the Associated Professional Sleep Societies, San Francisco, CA, June 1997.

Clete A. Kushida, M.D., Ph.D., RPSGT 30

“A predictive morphometric model for obstructive sleep apnea.” Speaker, Oral Presentation, Sleep Disorders Dental Society Annual Meeting, San Francisco, CA, June 12, 1997.

“Allergic rhinitis and sleep apnea: What is the connection in the workplace?” Speaker, Annual Meeting of the American College of Occupational and Environmental Medicine, Orlando, FL, May 1997.

“The relationship of allergic rhinitis and immune function with sleep apnea.” Speaker, Combined Allergy/Immunology Meeting, Acapulco, Mexico, January 1997.

“Allergic rhinitis: links to snoring and sleep apnea.” Speaker, Meeting of the American Academy of Family Physicians, New Orleans, LA, October 1996.

“New technology in sleep medicine.” Chair, Discussion Group Session, Tenth Annual Meeting of the Associated Professional Sleep Societies, Washington D.C., May 31, 1996.

“Clinical prediction of obstructive sleep apnea by a morphometric model.” Speaker, Tenth Annual Meeting of the Associated Professional Sleep Societies, Washington D.C., June 2, 1996.

“Genetics and craniofacial dysmorphism in family studies of obstructive sleep apnea.” Speaker, Tenth Annual Meeting of the Associated Professional Sleep Societies, Washington D.C., May 30, 1996.

“SleepLinkTM: An interactive linked computer program for sleep data analysis.” Speaker, Oral Presentation, Tenth Annual Meeting of the Associated Professional Sleep Societies, Washington D.C., June 1996.

“Autoradiographic analysis of narcoleptic canine brains following 14C-2-deoxyglucose administration during drug-induced cataplectic attacks.” Speaker, Oral Presentation, Tenth Annual Meeting of the Associated Professional Sleep Societies, Washington D.C., May 30, 1996.

“Clinical prediction of obstructive sleep apnea by a morphometric model.” Speaker, Oral Presentation, Forty-Eighth Annual Meeting of the American Academy of Neurology, San Francisco, CA, March 28, 1996.

“The neurobiology of sleep deprivation.” Panel Discussant with H.A. Emsellem and C. Everson, Twenty-Ninth Annual Winter Conference on Brain Research, Snowmass, CO, January 29, 1996.

“The genetics of obstructive sleep apnea.” Speaker, Western Regional Association of Polysomnographic Technologists Meeting, Lake Tahoe, CA, October 1995.

“Narcolepsy.” Chair, Oral Communication Session Chair, Ninth Annual Meeting of the Associated Professional Sleep Societies, Nashville, TN, June 4, 1995.

“A predictive morphometric model for obstructive sleep apnea.” Speaker, Oral Presentation, Ninth Annual Meeting of the Associated Professional Sleep Societies, Nashville, TN, June 1, 1995.

“Genetic patterns in craniofacial dysmorphism of obstructive sleep apnea patients.” Speaker, Oral Presentation, Ninth Annual Meeting of the Associated Professional Sleep Societies, Nashville, TN, June 3, 1995.

“Expression of m2 muscarinic receptor mRNA in rat brain with REM sleep deprivation.” Speaker, Oral Presentation, Ninth Annual Meeting of the Associated Professional Sleep Societies, Nashville, TN, June 2, 1995.

“Neurophysiology II.” Chair, Oral Communication Session, Eighth Annual Meeting of the Associated Professional Sleep Societies, Boston, MA, June 1994.

“Expression of m3 muscarinic receptor mRNA in rat brain with REM sleep deprivation.” Speaker, Oral Presentation, Eighth Annual Meeting of the Associated Professional Sleep Societies, Boston, MA, June 1994.

“Expression of m1 muscarinic receptor mRNA in rat brain with REM sleep deprivation.” Speaker, oral Presentation, Seventh Annual Meeting of the Associated Professional Sleep Societies, Los Angeles, CA, June 24, 1993.

“The effects of chronic REM sleep deprivation in the rat.” Speaker, JABSOM Biomedical Sciences Symposium, Honolulu, HI, October 1990.

“The effects of chronic REM sleep deprivation in the rat.” Speaker, Forty-fourth Annual Senior Scientific Session, University of Chicago, IL, May 1990.

“Quantitative assessment of changes in student attitudes throughout medical school.” Speaker, Annual meeting of the Central Region Organization of Student Representatives of the Association of American Medical Colleges, Itasca, IL, April 1988.

“Marketing your medical school: Is it time for a new approach?” Panel Discussant with D. Burr, J. Mendelsohn, A. Sturm, and V. Crowder. Annual Meeting of the Central Region Group on Student Affairs of the Association of American Medical Colleges, Itasca, IL, April 16, 1988.

“The effects of chronic paradoxical sleep deprivation in the rat.” Speaker, First Annual Graduate Student Symposium of the Program for Biological Approaches to Behavior, University of Chicago, IL, June 1987.

Clete A. Kushida, M.D., Ph.D., RPSGT 31

“Physiological and biochemical effects of paradoxical sleep deprivation in the rat.” Speaker, First Annual Meeting of the Associated Professional Sleep Societies, Columbus, OH, June 17, 1986.

“Paradoxical sleep deprivation in the rat: I. Physiological effects.” Speaker, Twenty-fourth Annual Meeting of the Sleep Research Society, Toronto, Ontario, May 31, 1984.

“Spontaneous and drug-induced cataplexy in narcoleptic Doberman pinschers.” Speaker, Sixth Annual Biological Sciences Undergraduate Research Conference, Santa Clara, CA, May 1981.

Invited Presentations at International Meetings

“World sleep education, training, and research.” Asian Sleep Research Society Mini-Symposium, The Fortieth Annual Meeting of the Japanese Society of Sleep Research, Utsunomiya, Japan, July 4, 2015.

“Obstructive sleep apnea and new treatment: The effectiveness of nasal airway stent.” The Fortieth Annual Meeting of the Japanese Society of Sleep Research, Utsunomiya, Japan, July 3, 2015.

“Sustainable Methods, Algorithms, and Research Tools for Delivering Optimal Care Study (SMART DOCS).” The Fortieth Annual Meeting of the Japanese Society of Sleep Research, Utsunomiya, Japan, July 2, 2015.

“Sleep and common sleep disorders.” All India Institute of Medical Sciences, New Delhi, India, September 26, 2014

“Sleep education around the world and WSF initiatives.” ASRS 2014: Asian Sleep Research Society Meeting, Kovalam, Thiruvananthapuram, Kerala, India, September 24, 2014.

“World sleep medicine education and certification.” The Second Asian Sleep Research Society Summit, Singapore, April 18, 2014.

“Titrating and monitoring non-invasive ventilation use.” XIV Brazilian Sleep Congress, Rio de Janeiro, Brazil, November 23, 2013.

“Comparative Outcomes Management with Electronic Data Technology (COMET) Study.” Ninth International Symposium on Respiratory Diseases and American Thoracic Society in China Forum, Shanghai, China, November 8, 2013.

“Obstructive Sleep Apnea and Neurologic Disease.” Postgraduate Course on Sleep Medicine, Ninth International Symposium on Respiratory Diseases and American Thoracic Society in China Forum, Shanghai, China, November 6, 2013.

“Titrating and monitoring non-invasive ventilation use.” Post-Annual Scientific Meeting Workshop: Paediatric Home Non-Invasive Ventilation Workshop, Hong Kong Society of Paediatric Respirology, Hong Kong SAR, China, October 7, 2013.

“The nose and obstructive sleep apnea: Pathogenesis and therapeutic implications.” Speaker, 1st Asian Paediatric Respirology Forum and 16th Hong Kong Society of Paediatric Respirology Annual Scientific Meeting, Hong Kong SAR, China, October 6, 2013.

“Free Paper Presentations.” Judge, 1st Asian Paediatric Respirology Forum and 16th Hong Kong Society of Paediatric Respirology Annual Scientific Meeting, Hong Kong SAR, China, October 6, 2013.

“Sleep medicine: A global perspective.” Annual Scientific Meeting, Hong Kong Society of Sleep Medicine, Hong Kong SAR, China, October 5, 2013.

“Insomnia”, “Sleep and medical disorders”, “Hypersomnias and narcolepsy”, “Sleep and neurological diseases”, “Restless legs syndrome/Periodic limb movement disorder”, and “Sleep and medications.” Speaker, Sleep Review Course, Kwong Kah Hospital, Hong Kong SAR, China, October 3-5, 2013.

“A role for oral appliance therapy and practice parameters update.” Keynote Speaker, Sleep Disordered Breathing in Dental School Education: Past, Present, and Future Conference, University of North Carolina, Chapel Hill, NC, August 24, 2013.

“Neurocognitive function and obstructive sleep apnea.” Department of Sleep Medicine, University of São Paulo, Brazil, May 6, 2013.

“Comparative Outcomes Management with Electronic Data Technology (COMET) Registry.” American Academy of Dental Sleep Medicine ORANGE Oral Appliance Registry Development Task Force Meeting, Paris, France, March 30, 2013.

“Primary outcomes data from the Apnea Positive Pressure Long-term Efficacy Study (APPLES).” Keynote Speaker, 8th International Symposium on Respiratory Diseases and American Thoracic Society in China Forum 2012, Shanghai, China, November 9, 2012.

“Primary session on respiratory and sleep medicine.” Co-Chair, 8th International Symposium on Respiratory Diseases and American Thoracic Society in China Forum 2012, Shanghai, China, November 9, 2012.

Clete A. Kushida, M.D., Ph.D., RPSGT 32

“Opportunities and challenges for sleep medicine, research, and education.” Speaker, Symposium on Sleep Apnea, 8th International Symposium on Respiratory Diseases and American Thoracic Society in China Forum 2012, Shanghai, China, November 9, 2012.

“Unusual movements and behaviors during sleep.” Speaker, Postgraduate Course, 8th International Symposium on Respiratory Diseases and American Thoracic Society in China Forum 2012, Shanghai, China, November 8, 2012.

“Sleep medicine training and certification.” Speaker, European Sleep Research Society, Japanese Society for Sleep Research, and World Sleep Federation Joint Symposium, 21st Congress of the European Sleep Research Society, Paris, France, September 8, 2012.

“Sleep disordered breathing – treatment.” Co-Chair, 21st Congress of the European Sleep Research Society, Paris, France, September 8, 2012.

“Various teaching models in the outpatient setting” and “Clinical teaching in the outpatient setting.” Speaker, Faculty Development Program, Hiroshima University Hospital, Hiroshima, Japan, November 21-22, 2011.

“Current management strategies for restless legs syndrome.” Speaker, Sixth World Congress of the World Sleep Federation (Worldsleep2011), Kyoto, Japan, October 19, 2011.

“Opportunities in comparative effectiveness research.” Speaker, Sleep-Disordered Breathing: Comparative Effectiveness Research, Sixth World Congress of the World Sleep Federation (Worldsleep2011), Kyoto, Japan, October 18, 2011.

“Diagnosis and treatment of sleep related movement disorders.” Speaker, 36th Annual Meeting of the Japanese Society of Sleep Research (JSSR36th), Kyoto, Japan, October 17, 2011.

“Challenges and opportunities for sleep medicine and educational/training initiatives.” Speaker, Sleep Medicine and Education in Asia, 36th Annual Meeting of the Japanese Society of Sleep Research (JSSR36th), Kyoto, Japan, October 16, 2011.

“Future of home sleep testing.” Speaker, Sixth World Congress of the World Sleep Federation (Worldsleep2011), Kyoto, Japan, October 15, 2011.

“Development of sleep medicine in the United States.” Speaker, Sixth Congress of Chinese Sleep Research Society (CSRS), Chengdu City, Sichuan Province, China, October 30, 2010

“The Apnea Positive Pressure Long-term Efficacy Study (APPLES) and the impact on neurocognitive testing in OSA patients.” Speaker, Second Joint Sino-German Sleep Research Symposium, Chengdu City, Sichuan Province, China, October 29, 2010.

“Certification and accreditation in sleep medicine around the world.” Round Table Discussant, Twentieth Congress of the European Sleep Research Society, Lisbon, Portugal, September 26, 2010.

“Lessons from APPLES relevant to cardiovascular disease trials.” Speaker, National Institutes of Health Conference - Translation and Clinical Trials: CVD outcomes in OSA Clinical Trials, Bethesda, MD, September 8, 2010.

“An update on approach to daytime sleepiness.” Speaker, Comprehensive Workshop on Clinical Polysomnography and Update Course on Sleep Medicine, Hong Kong, September 4, 2010.

“Sleep-related movements from children to elderly.” Speaker, Comprehensive Workshop on Clinical Polysomnography and Update Course on Sleep Medicine, Hong Kong, September 4, 2010.

“Chronobiology, sleep, and medical disorders.” Speaker, Comprehensive Workshop on Clinical Polysomnography and Update Course on Sleep Medicine, Hong Kong, September 4, 2010.

“What’s new about AASM scoring rules: Rationale and applications.” Speaker, Comprehensive Workshop on Clinical Polysomnography and Update Course on Sleep Medicine, Hong Kong, September 3, 2010.

“AASM direction of accreditation and continual education for clinicians and technologists.” Speaker, Comprehensive Workshop on Clinical Polysomnography and Update Course on Sleep Medicine, Hong Kong, September 3, 2010.

“The future for sleep medicine and sleep research.” Keynote Speaker, International Sleep Medicine Symposium 2010: New Perspectives in Sleep Medicine, Berlin, Germany, May 13, 2010.

“Overview of the American Academy of Sleep Medicine (AASM) sleep physician certification examination.” Speaker, 2010 Beijing Sleep Medicine Forum and the Joint Sleep Training Course between The People’s Hospital, Peking University and Network of Asia-Pacific Sleep Technologists (NAPST), The People’s Hospital, Peking University, Beijing, China, April 18, 2010.

“Sleep-related movement disorders.” 2010 Beijing International Sleep Medicine Forum, The People’s Hospital, Peking University, Beijing, China, April 17, 2010.

“Adaptive servoventilation.” Speaker, Network of Asia-Pacific Sleep Technologists (NAPST) 2010: Asia-Pacific Sleep Matters, The People’s Hospital, Peking University, Beijing, China, April 16, 2010.

Clete A. Kushida, M.D., Ph.D., RPSGT 33

“Sleep-related movement disorders.” Speaker, Network of Asia-Pacific Sleep Technologists (NAPST) 2010: Asia-Pacific Sleep Matters, Peking People’s University Hospital, Beijing, China, April 16, 2010.

“Transitional board certification tools for international sleep specialists.” Keynote Speaker, Taiwan Society of Sleep Medicine Meeting, Taipei, Taiwan, March 21, 2010.

“Cheyne-Stokes respiration and central apneas in heart failure: Diagnosis and treatment.” Speaker, The Second Congress of Sleep Disorders, Turkish Republic of Northern Cypress, March 19, 2010.

“Sleep apnea syndrome and hypertension.” Speaker, The Second Congress of Sleep Disorders, Turkish Republic of Northern Cypress, March 19, 2010.

“Sleep education and research: Challenges and opportunities.” Speaker, The First Asian Sleep Research Society Summit and Symposium of Asia Oceania Sleep Research and Sleep Medicine in Okinawa, Japan, October 31, 2009.

“Introduction of sleep medicine: Past, present, and future.” Speaker, Ryukyu University School of Medicine, Okinawa, Japan, October 29, 2009.

“The AASM guideline for diagnosis and treatment of narcolepsy and research update on related disorders.” Speaker, Ahead of a New Era in Sleep and Chronobiology Research from Asia, Joint Congress 2009: The 6th Congress of Asian Sleep Research Society, The 34th Annual Meeting of Japanese Society of Sleep Research, and The 16th Annual Meeting of Japanese Society for Chronobiology, Osaka, Japan, October 25, 2009.

“Updates on restless legs syndrome.” Speaker, Ahead of a New Era in Sleep and Chronobiology Research from Asia, Joint Congress 2009: The 6th Congress of Asian Sleep Research Society, The 34th Annual Meeting of Japanese Society of Sleep Research, and The 16th Annual Meeting of Japanese Society for Chronobiology, Osaka, Japan, October 25, 2009.

“Apnea positive pressure long-term efficacy study (APPLES).” Speaker, Ninth World Congress on Sleep Apnea, Seoul, Korea, March 26, 2009.

“The use of esophageal manometry in the diagnosis of sleep-related breathing disorders.” Speaker, Beijing International Symposium on Clinical Neuro-technology and Neuroscience (BIS-CNN) Meeting, Beijing, China, October 25, 2008.

“Basic mechanisms: Neuroanatomy and neurophysiology of sleep” and “Movement disorders: AASM Scoring Manual (2007.” Speaker, Second Annual Network of Asia-Pacific Sleep Technologists (NAPST) and Hawaii Sleep Society Joint Conference, Honolulu, HI, September 12, 2008.

“Workshop: Education for physicians and sleep technologists in China.” Sleepless in Beijing 2008, Second Annual Network of Asia Pacific Sleep Technologists (NAPST) Sleep Technology Conference, Beijing, China, March 30, 2008.

“Overview of sleep movement disorder.” Keynote Speaker, 2008 Beijing International Sleep Medicine Forum, Beijing, China, March 29, 2008.

“Update in narcolepsy research.” Keynote Speaker, Narcolepsy in Asia 2008, The People’s Hospital, Peking University, China, March 28, 2008.

“Sleep medicine.” Guest Speaker, Department of Physiology, Siriraj Hospital, Mahidol University, Bangkok, Thailand, March 19, 2008.

“Restless legs syndrome.” Guest Speaker, A new Era of Best Practice and Innovation, Siriraj Scientific Congress – The 120th Anniversary of Siriraj Hospital, Bangkok, Thailand, March 18, 2008.

“Overview of AASM manual for scoring sleep, 2007.” Keynote Speaker, Fourth Ansan International Sleep Workshop: Review of the New AASM Manual for Scoring Sleep, 2007, Ansan Hospital, Korea University, Seoul, Korea, November 3, 2007.

“Movement rules with sleep related movement disorder and parasomnia”, “Case review for basic PSG scoring”, and “Management for complex sleep apnea.” Invited Speaker, Fourth Ansan International Sleep Workshop: Review of the New AASM Manual for Scoring Sleep, 2007, Ansan, Korea, November 3-4, 2007.

“Insomnias”, “Parasomnias”, and “Hypersomnias of central origin and narcolepsy.” Invited Speaker, Third Ansan Sleep Workshop: Review of ICSD-2 and Practical Exercises of PSG and CPAP, Ansan Hospital, Korea University, Seoul, Korea, May 12-13, 2007.

“Overview of sleep disorders” and “Somnopharmacology.” Network of Asia-Pacific Sleep Technologists (NAPST): Asia Pacific Sleep Technology Conference, Honolulu, HI, March 24-25, 2007.

“Parasomnias” and “Restless legs syndrome and periodic limb movement disorder.” Invited Speaker, Korea University Medical Center Ansan Hospital, Seoul, Korea, October 14, 2006.

“Insomnia: diagnosis and treatment” and “Restless legs syndrome and periodic limb movement disorder.” Invited Speaker, Second Annual Meeting of the Korean Sleep Society, Seoul, Korea, July 3, 2005.

“Common sleep disorders.” Korean Neurologic Sleep Group Meeting, Seoul, Korea, July 2, 2005.

Clete A. Kushida, M.D., Ph.D., RPSGT 34

“The Moscow study: Restless legs syndrome.” RLS Venice Club Meeting, Venice, Italy, March 22, 2003. “The relationship of sleep-disordered breathing and the cardiovascular system.” Obstructive Sleep Apnea

Syndrome and Cardiovascular Disease: Seminar on Sleep Disorders, Taipei, Taiwan, November 2002.

“Clinical polysomnography and continuous positive airway pressure.” Sleep Workshops, Taipei, Taiwan and Kaohsiung, Taiwan, November 2002.

“Sleep medicine clinical and research laboratories.” Tokyo, Japan, August 5, 2001. “Sleep outcomes.” Sleep Symposium, Tokyo, Japan, March 2001. “Screening and case findings for sleep apnea”, “A predictive morphometric model for OSA”, and

“Common sleep disorders: Diagnosis and management.” Sleep Symposium, Bangkok, Thailand, February 27, 2001.

“Common sleep disorders: Diagnosis and management” and “New findings in the diagnosis and treatment of obstructive sleep apnea.” Sleep Medicine Seminar, Taipei, Taiwan, February 2001.

“New findings in obstructive sleep apnea and CPAP therapy.” Sleep Seminar, Tokyo, Japan, November 2000.

“Indications for CPAP therapy and long-term management of the OSA patients.” Sleep Symposium, Osaka, Japan, November 2000.

“Sleep apnea and sudden infant death syndrome.” Sleep Seminar, Nagoya, Japan, November 2000. “Indications for CPAP therapy and long-term management of the OSA patients.” Clinical CPAP Society

Symposium, Osaka, Japan, May 20, 2000. “Remote monitoring of sleep disorders.” De La Salle University, Philippines, January 19, 2000. “Sleep apnea.” Asian Sleep Society, Taipei, Taiwan, September 1999. “Non-surgical treatment of sleep apnea.” Tokyo, Japan, September 1999. “Sleep disorders, EEG disturbances, and EMF exposure.” International Workshop on Electromagnetic

Fields and Non-Specific Health Symptoms, Graz, Austria, September 1998. “Common sleep disorders: Evaluation and management.” Current Issues in Selected Medical Topics

Symposium, St. George’s School of Medicine, Grenada, West Indies, February 9, 1997. Invited Presentations at National Meetings

“Sleep and sleep disorders.” Edwards Lifesciences, Gateway Canyons, CO, July 12, 2014. “Comparative Outcomes Management with Electronic Data Technology (COMET) Study.” Electronic

Health Record (EHR) Data Infrastructure for Patient-Centered Outcomes Research (PCOR) Panel Meeting, Washington D.C., April 19, 2013.

“Neurological associations of common sleep disorders.” Western Society of Electrodiagnostic Technologists 2013 Annual Meeting, San Francisco, CA, March 8, 2013.

“Research networks.” Co-Chair, Sleep and Circadian Research: Identification of Transformative Scientific Questions and Opportunities, Bethesda, MD, February 1, 2013.

“Update on the Comparative Outcomes Management with Electronic Data Technology (COMET) Study.” Electronic Data Technology (EDM) Forum Steering Committee Meeting, Rockville, MD, January 10, 2013.

“Strategies for de-identification and anonymization of electronic health record data in multicenter research studies.” Electronic Data Methods (EDM) Forum Symposium: Building an Electronic Clinical Data Infrastructure to Improve Patient Outcomes, Lake Buena Vista, FL, June 23, 2012.

“Bill Dement as a mentor.” Reception Honoring Dr. William C. Dement, Twenty-Fifth Anniversary Meeting of the Associated Professional Sleep Societies, Minneapolis, MN, June 13, 2011.

“Data management.” AHRQ Electronic Data Management Forum Meeting, Washington DC, April 8, 2011. “Sleep related movement disorders.” 33rd Annual Southern Sleep Society Meeting, New Orleans, LA,

March 26, 2011. “Outcomes and registries.” Future of Sleep Medicine Meeting, American Academy of Sleep Medicine, San

Diego, CA, February 19, 2011. “Comparative Outcomes Management with Electronic Data Technology (COMET) Study.” Clinical and

Translational Science Awards (CTSA) Consortium Sleep Research Network, Bethesda, MD, October 15, 2010.

“Neurocognitive testing.” American Academy of Sleep Medicine Future of Sleep Medicine Conference, Chicago, IL, October 11, 2010.

“American Academy of Sleep Medicine Immediate Past Presidential Address.” Thirty-Second Annual Meeting of the Associated Professional Sleep Societies, San Antonio, TX, June 6, 2010

Clete A. Kushida, M.D., Ph.D., RPSGT 35

“American Academy of Sleep Medicine President’s Remarks.” Thirty-Second Annual Meeting of the Associated Professional Sleep Societies, San Antonio, TX, June 6, 2010

“The tired and the restless: It may be restless legs syndrome.” Practicing Clinicians Exchange CME Meetings, Foster City, CA (October 17, 2009), Melville, NY (November 21, 2009).

“Parasomnias.” American Society of Electroneurodiagnostic Technologists, Pasadena, CA, October 2, 2009.

“American Academy of Sleep Medicine Presidential Address.” Thirty-First Annual Meeting of the Associated Professional Sleep Societies, Seattle, WA, June 10, 2009.

“Clinical trials: Design, competencies, and execution.” American Academy of Sleep Medicine Young Investigator Forum at NIH, Bethesda, MD, April 15, 2009.

“Data management: Apnea Positive Pressure Long-term Efficacy Study (APPLES).” First University of Pittsburgh Clinical and Translation Science Awards (CTSA) / Sleep Medicine Institute Sleep Consortium Conference, Pittsburgh, PA, June 23, 2008.

“Formation of the California Sleep Society.” Thirtieth Annual Meeting of the Associated Professional Sleep Societies, Baltimore, MD, June 8, 2008.

“Presentation skills.” Thirteenth Annual Trainee Symposia Series, Sleep Research Society, Thirtieth Annual Meeting of the Associated Professional Sleep Societies, Baltimore, MD, June 8, 2008.

“Clinical guidelines for manual PAP titration.” Respironics, Inc., Sleep and Home Respiratory Headquarters, Pittsburgh, PA, May 30, 2008.

“Sleep apnea and learning in adults.” The Role of Sleep in Memory and Learning National Conference, National Sleep Foundation, Washington, DC, March 4, 2008.

“The scoring of movements in sleep.” Advances in Sleep Technology: A review of the Scoring of Sleep and Associated Events Course by the American Association of Sleep Technologists (AAST), Louisville, KY, February 23, 2008.

“On the move: Recent advances in restless legs syndrome (RLS) and Parkinson’s disease (PD).” Pri-Med Updates Meeting, Portland, OR, November 28, 2007.

“Past, present and future (opportunities) in sleep medicine.” Keynote Speaker, First Annual Sleep Medicine Conference, Sleep Technology: The Building Blocks of Tomorrow, University of Pittsburgh School of Medicine, Pittsburgh, PA, November 9, 2007.

“On the move: Recent advances in restless legs syndrome (RLS) and Parkinson’s disease (PD).” Pri-Med Updates Meeting, Seattle, WA, October 19, 2007.

“Portable monitoring.” Facilitator, Workshop, American Thoracic Society, American Academy of Sleep Medicine, American College of Chest Physicians, and European Respiratory Society, Washington, DC, October 15-17, 2007.

“Diagnosis and treatment of restless leg syndrome” and “Therapeutic alternatives in the management of sleep apnea.” Invited Speaker, Twenty-Fourth Annual Clinical Update of Pulmonary Disease, Deborah Heart and Lung Center, Philadelphia, PA, September 8, 2007.

“Sleep apnea: Epidemiology and gender differences.” Kuakini Medical Center, Honolulu, HI, August 31, 2007.

“Unusual movements observed during your patient’s sleep.” Invited Lecturer, Twenty-First Annual Meeting of the American Association of Sleep Technologists, Minneapolis, Minneapolis, MN, June 13, 2007.

“Using and scoring actigraphy.” Twelfth Annual Trainee Symposia Series, Sleep Research Society, Twenty-Ninth Annual Meeting of the Associated Professional Sleep Societies, Minneapolis, MN, June 10, 2007.

“OSA epidemiology and gender differences.” Invited Lecturer, Sixteenth Annual Meeting of the American Academy of Dental Sleep Medicine, Minneapolis, MN, June 9, 2007.

“Apnea positive pressure long-term efficacy study (APPLES).” Co-Chair, Division of Lung Diseases/National Heart, Lung, and Blood Institute Symposium, American Thoracic Society 2007 International Conference, San Francisco, CA, May 21, 2007.

“Non-pharmacologic treatment of sleep disorders.” Invited Lecturer, Tenth Annual Meeting of The College of Psychiatric and Neurologic Pharmacists (CPNP), Colorado Springs, CO, April 17, 2007.

“Restless legs, restless nights: Putting restless legs syndrome to bed.” Pri-Med Updates Meeting, Minneapolis, MN, November 11, 2006.

“Restless legs, restless nights: Putting restless legs syndrome to bed.” Pri-Med Updates Meeting, South Baltimore, MD, October 21, 2006.

“Common sleep problems.” Sleep Medicine Symposium, University of Hawaii, HI, September 11, 2006.

Clete A. Kushida, M.D., Ph.D., RPSGT 36

“The many faces of restless legs syndrome: Diagnosis and treatment in primary care.” Pri-Med Updates Meetings, Anaheim, CA (April 19, 2006), South San Francisco, CA (September 21, 2006), Baltimore, MD (October 21, 2006), Minneapolis, MN (November 10, 2006).

“Neurophysiology of sleep” and “Medication effects on sleep.” Spring Review Course of the Association of Polysomnographic Technologists, St. Louis, MO, April 10, 2006.

“Old syndrome, new therapies − Restless leg syndrome.” Annual Meeting and Exposition of the American Pharmacists Association, San Francisco, CA, March 20, 2006.

“Parasomnias” and “Restless legs syndrome and periodic limb movement disorder.” Invited Lecturer, Winter Update 2006, University of South Dakota School of Medicine, Sioux Falls, SD, February 10-11, 2006.

“Managing insomnia: Challenges for the primary care physician.” Pri-Med Updates Meeting, Portland, OR, November 29, 2005.

“Introduction to polysomnography”, “Restless legs syndrome – periodic limb movement disorder”, “Parasomnias”, and “Meet-the-Professor” Sessions for “Pitfalls in polysomnography” and “Restless legs – treatment considerations.” Sleep Medicine 2005, Lake Buena Vista, Florida, November 7-9, 2005.

“Parasomnias.” Internal Medicine Grand Rounds, Texas Health Resources, Lecture at Presbyterian Hospital of Dallas with a live webcast to Harris Methodist and Arlington Memorial Hospital, Dallas, TX, September 14, 2005.

“Treatment of the restless legs syndrome.” Fifth Annual North American Women’s Healthcare Forum, Anaheim, California, May 7, 2005.

“Update in obstructive sleep apnea”, “The restless legs syndrome”, and “Parasomnias.” Fifth Annual Symposium: Current Concepts in Pulmonary and Critical Care, American Lung Association of Hawaii and Hawaii Thoracic Society, Wailea, Maui, HI, February 20-23, 2005.

“Common sleep problems.” Medicine Grand Rounds, Kuakini Medical Center, Honolulu, HI, December 16, 2004.

“Restless legs, restless nights: Innovations in the treatment of RLS.” Pri-Med Updates Meeting, St. Louis, MO, October 1, 2004.

“Optimizing your presentation skills.” Ninth Annual Trainee Symposium Series, Eighteenth Annual Meeting of the Associated Professional Sleep Societies, Philadelphia, PA, June 6, 2004.

“Fill your plate: Fortify your knowledge of movement disorders.” Intellyst CME Primary Care Meeting, New York, NY (May 15, 2004), Sacramento, CA (May 17, 2004).

“Clinical presentation and diagnosis of restless legs syndrome.” Sleeping With the Enemy: Restless Legs Syndrome Uncovered. CME-Satellite Video Lecture broadcasted live to 3,500 Primary Care Physicians, Neurologists, and Physician Assistants, March 27, 2004.

“The daily special: Discussions on movement disorders.” Intellyst CME Primary Care Meetings, Santa Ana, CA (April 22, 2004), Seattle, WA (May 13, 2004), Sacramento, CA (May 17, 2004), Los Angeles, CA (May 20, 2004), San Diego, CA (June 14, 2004), Las Vegas, NV (June 17, 2004), Seattle, WA (July 8, 2004), Los Angeles, CA (July 15, 2004), Boston, MA (August 30, 2004), San Jose, CA (September 27, 2004).

“Sleep apnea and insomnia.” Medicine Grand Rounds, Kaiser Permanente Medical Center, Honolulu, HI, July 17, 2003.

“Shift work and sleep hygiene.” Sleep Medicine Symposium, Kuakini Medical Center, Honolulu, HI, July 16, 2003.

“Scenes from restless legs syndrome: Movers and shakers. CME-Satellite Video Lecture broadcasted live to 3,500 Primary Care Physicians, Neurologists, and Physician Assistants, June 14, 2003.

“Behavioral therapy for OSAS, RLS, PLMS, and narcolepsy.” Trainee Day at the Seventeenth Annual Meeting of the Associated Professional Sleep Societies, Chicago, IL, June 4, 2003.

“The main course: Serving up new information, data, and treatments on movement disorders.” Intellyst CME Primary Care Meetings, Los Angeles, CA (May 12, 2003), San Jose, CA (May 19, 2003), Oakland, CA (May 22, 2003), San Francisco, CA (May 29, 2003), Santa Ana, CA (June 12, 2003), San Diego, CA (June 26, 2003), Los Angeles, CA (July 24, 2003), Riverside, CA (July 31, 2003), San Francisco, CA (September 8, 2003), Seattle, WA (September 11, 2003), Long Beach, CA (September 25, 2003), Santa Ana, CA (September 29, 2003), Las Vegas, NV (October 16, 2003), Sacramento, CA (January 26, 2004), Seattle, WA (February 9, 2004), Los Angeles, CA (February 19, 2004), Santa Ana, CA (February 26, 2004).

“Sleep disorders.” “Nighttime leg disorders.” American Academy of Family Physicians Geriatrics Medicine Course, Destin, FL, October 6, 2002.

Clete A. Kushida, M.D., Ph.D., RPSGT 37

“Effects of modafinil on PLMD-associated daytime sleepiness.” Scientific/Clinical Update on Modafinil Meeting, Scottsdale, AZ, September 21, 2002.

“Insomnia”, “Parasomnias”, and “Restless legs syndrome and periodic limb movement disorder.” Speaker, Polysomnographic Technologist Course, Hawaii Thoracic Society and the Hawaii School of Sleep Medicine and Technology, Kuakini Medical Center, Honolulu, HI, July 22, 2002.

“Sleep disorders.” Joint Meeting of the Society for Neuronal Regulation (SNR) and the EEG Clinical and Neuroscience Society (ECNS) Meeting, Monterey, CA, October 26, 2001.

“Insomnia and sleep disorders in the elderly” and “Nighttime leg disorders.” Speaker, Geriatric Medicine for the Family Physician Course, American Academy of Family Physicians, Monterey, CA, September 16, 2001.

“Sleep Disorders.” Nikken Expo, Fort Worth, TX, January 2001. “Common sleep disorders.” October Primary Care CME Conference, Dallas, TX, October 2000. “Restless legs syndrome and periodic limb movement disorder”, “Narcolepsy”, and “Outcomes

management.” Speaker, Polysomnographic Technologist Course, Hawaii School of Sleep Medicine and Technology, Kuakini Medical Center, Honolulu, HI, February 18, 2000.

“Insomnia”, “Parasomnias”, and “Outcomes management.” Speaker, Polysomnographic Technologist Course, Hawaii School of Sleep Medicine and Technology, Kuakini Medical Center, Honolulu, HI, October 15, 1999.

“Restless legs syndrome and periodic limb movement disorder”, “Narcolepsy”, and “Outcomes management.” Speaker, Polysomnographic Technologist Course, Hawaii School of Sleep Medicine and Technology, Kuakini Medical Center, Honolulu, HI, July 9, 1999.

“Optimizing your presentation skills.” Fourth Annual Trainee Symposium Series, Thirteenth Annual Meeting of the Associated Professional Sleep Societies, Orlando, FL, June 1999.

“Cervical positioning and obstructive sleep apnea.” Life Sleep Systems Medical Advisory Board Meeting, Orlando, FL, June 1999.

“Basic mechanisms of sleep.” 1999 Kershman Memorial Lecture, Eastern Association of Electroencephalographers Meeting, New York, NY, March 12, 1999.

“Narcolepsy”, “Parasomnias”, and “Outcomes management.” Speaker, Polysomnographic Technologist Course, Hawaii School of Sleep Medicine and Technology, Kuakini Medical Center, Honolulu, HI, July 17, 1998.

“How to deliver great presentations.” Third Annual Trainee Symposium Series, Twelfth Annual Meeting of the Associated Professional Sleep Societies, New Orleans, LA, June 1998.

“Nasal obstruction and sleep apnea.” Risk Management in Asthma and Allergic Disease Seminars, Philadelphia, PA (April 25, 1998), San Diego, CA (May 23, 1998), New York, NY (June 13, 1998).

“Narcolepsy”, “Sleep related seizures”, and “Outcomes management.” Speaker, Polysomnographic Technologist Course, Hawaii School of Sleep Medicine and Technology, Kuakini Medical Center, Honolulu, HI, February 20, 1998.

“Chronic pain and sleep.” Association of Rheumatology Health Professionals and Arthritis Foundation, San Francisco, CA, October 1997.

“New developments in the diagnosis and management of sleep disorders.” Grand Rounds, University of Hawaii Medical Centers, Honolulu, HI, July 1997.

“Clinical sleep medicine careers.” Eleventh Annual Meeting of the Associated Professional Sleep Societies, San Francisco, CA, June 10, 1997.

“The connection between allergic rhinitis and sleep apnea.” Annual Meeting of the American College of Physicians, Philadelphia, PA, March 1997.

“The connection between allergic rhinitis and sleep apnea.” Thirty-Fourth Annual Convention and Scientific Seminar of the American College of Osteopathic Family Physicians, Anaheim, CA, March 1997.

“New developments in basic sleep mechanisms.” Neurology Grand Rounds, Emory University School of Medicine, Atlanta, GA, October 1996.

Invited Presentations at State and Regional Meetings

“Obstructive sleep apnea.” Stanford Cardiothoracic Nursing Group, Stanford Hospital and Clinics, CA, August 20, 2014.

“Update on sleep disorders.” Sustainable Methods, Algorithms, and Research Tools for Delivering Optimal Care Study – Patient Engagement Session, Stanford Sleep Medicine Center, CA, August 12, 2014.

“Sleep and sleep disorders.” Apple Wellness Center, Cupertino, CA, July 25, 2014.

Clete A. Kushida, M.D., Ph.D., RPSGT 38

“Basic mechanisms of sleep.” Sleep Disorders, Physiology of Sleep, and Chronobiology: Clinical Review for Sleep Medicine Attending Physicians and Clinical Fellows, Stanford University, CA, July 25, 2014.

“Sleep service at Stanford Primary Care.” Primary Care Medical Directors’ Meeting, Stanford University, CA, July 23, 2014.

“Sleep deprivation.” Clinical Review for Sleep Medicine Attending Physicians and Clinical Fellows, Stanford University, CA, February 14, 2014.

“Parasomnias and seizures.” A-STEP Technologist Course, Stanford Sleep Medicine Center, CA, February 14, 2014.

“Electromyography and movement disorders.” A-STEP Technologist Course, Stanford Sleep Medicine Center, CA, February 14, 2014.

“Parasomnias.” Sleep and Dreams Course for Undergraduate students (PSYC 135), Stanford University, CA, February 7, 2014.

“Actigraphy and sleep diaries.” Clinical Review for Sleep Medicine Attending Physicians and Clinical Fellows, Stanford University, CA, January 17, 2014.

“Update on sleep disorders.” Primary Care CME Speaker Series, Stanford Primary Care Clinics, CA, December 12, 2013.

“Sleep disorders: Contribution to healthcare worker fatigue.” Stanford Hospital and Clinics Nursing Grand Rounds, Lucile Packard Children’s Hospital, December 4, 2013.

“Sleep and common sleep problems.” Stanford Hospital and Clinics Community Fellows Program, Stanford Medicine Outpatient Center, October 11, 2013.

“Basic sleep pathophysiology.” Stanford Pain Management Center, Stanford Medicine Outpatient Center, CA, September 30, 2013.

“Sleepless nights: Sleep problems and disorders.” Café Scientifique, Stanford Blood Center, Palo Alto, CA, September 26, 2013.

“Basic mechanisms of sleep.” Clinical Review for Sleep Medicine Attending Physicians and Clinical Fellows, Stanford University, CA, August 16, 2013.

“Sleep and pain.” Stanford Pain Management Center, Stanford Medicine Outpatient Center, CA, July 31, 2013.

“Sleep and common sleep problems.” HP Wellness Lunch and Learn Session, Hewett Packard (HP), Palo Alto, CA, May 29, 2013.

“Stanford Sleep Medicine Center Services.” AWAKE (Alert, Well, And Keeping Energetic obstructive sleep apnea patient support group) Meeting, Stanford, CA, May 1, 2013.

“Parasomnias.” Sleep and Dreams Course for Undergraduate students (PSYC 135), Stanford University, CA, April 29, 2013.

“Common sleep problems.” The Nueva School, Hillsborough, CA, March 6, 2013. “Obstructive sleep apnea.” Meet the M.D. Expert Lecture Series, The Cardiac Therapy Foundation of the

Mid-Peninsula, Palo Alto, CA, March 2, 2013. “Actigraphy and sleep diaries.” Clinical Review for Sleep Medicine Attending Physicians and Clinical

Fellows, Stanford University, CA, March 1, 2013. “Sleep and common sleep problems.” Stanford Hospital and Clinics Community Fellows Program,

Stanford Medicine Outpatient Center, February 8, 2013. “Sleep deprivation.” Clinical Review for Sleep Medicine Attending Physicians and Clinical Fellows,

Stanford University, CA, February 8, 2013. “Parasomnias.” Sleep and Dreams Course for Undergraduate students (PSYC 135), Stanford University,

CA, February 6, 2013. “Restless legs syndrome.” Sleep and Dreams Course for Undergraduate students (PSYC 135), Stanford

University, CA, February 4, 2013. “Restless legs syndrome and sleep related movement disorders.” A-STEP Technologist Course, Stanford

Sleep Medicine Center, CA, January 17, 2013. “Sleep and sleep problems.” J-Sei Senior Center, Berkeley, CA, October 15, 2012. “Sleep and common sleep problems.” Stanford University Health Improvement Program (HIP), Stanford,

CA, August 13, 2012. “Sleep, sleep loss, and sleep problems.” Stanford University Linear Accelerator Center, Workshop on

Accelerator Operations, Stanford University, CA, August 9, 2012. “Sleep and common sleep problems.” Redwood City-San Mateo County Chamber of Commerce

Leadership Program’s Healthcare Day, Stanford Medical Outpatient Center, May 11, 2012. “Sleep and common sleep disorders.” Stanford University BeWell Wellness Advisor Training Meeting,

Stanford University, CA, April 30, 2012.

Clete A. Kushida, M.D., Ph.D., RPSGT 39

“Sleep disorders.” Stanford University Second Annual Residential and Dining Enterprises Wellness Fair, Stanford University, CA, March 21, 2012.

“Sleep related movement disorders.” A-STEP Technologist Course, Stanford Sleep Medicine Center, CA, August 29, 2011.

“Obstructive sleep apnea.” A-STEP Technologist Course, Stanford Sleep Medicine Center, CA, August 25, 2011.

“Sleep medicine at Stanford.” A-STEP Technologist Course, Stanford Sleep Medicine Center, CA, August 22, 2011.

“Sleep disorders.” Stanford University Second Annual Residential and Dining Enterprises Wellness Fair, Stanford University, CA, August 22, 2011.

“Sleep medicine board certification examination overview.” School of Sleep Medicine, Palo Alto, CA, August 18, 2011.

“Sleep disorders and sleep apnea: Diagnosis and management.” Center for Education and Professional Development, Division of Patient Care Services, Stanford University, CA, July 13, 2011.

“Basic mechanisms of sleep.” Sleep Disorders, Physiology of Sleep, and Chronobiology: Clinical Review for Sleep Medicine Attending Physicians and Clinical Fellows, Stanford University, CA, July 8, 2011.

“The diagnosis and medical management of obstructive sleep apnea.” Stanford Hospitals and Clinics Clinical Care Update, San Francisco 49ers Headquarters, Santa Clara, CA, June 7, 2011.

“Sleep and sleep problems.” Men’s Health: Sleep and Fitness. Second Kenko Living Series Program, Akiyama Wellness Center, San Jose, CA, June 4, 2011.

“Comparative Outcomes Management with Electronic Data Technology (COMET) Study.” Sleep Medicine Grand Rounds, Stanford University. March 11, 2011.

“Comparative Outcomes Management with Electronic Data Technology (COMET) Study.” AHRQ Electronic Data Management Forum Meeting, Stanford University. March 10, 2011.

“Central nervous system hypersomnias” and “Circadian rhythm disorders.” University of Nebraska Medical Center Spring Sleep Conference, University of Nebraska, NE, March 4, 2011.

“Treatment of obstructive sleep apnea.” Sleep and Dreams Course for Undergraduate students (PSYC 135), Stanford University, CA, February 14, 2011.

“Diagnosis of obstructive sleep apnea.” Sleep and Dreams Course for Undergraduate students (PSYC 135), Stanford University, CA, February 11, 2011.

“Parasomnias.” Sleep and Dreams Course for Undergraduate students (PSYC 135), Stanford University, CA, February 4, 2011.

“Sleepless at Stanford: Exciting research that might keep you awake.” Classes Without Quizzes, Stanford Continuing Studies Program, Stanford University, November 13, 2010.

“Restless legs syndrome.” Clinical Review for Sleep Medicine Attending Physicians and Clinical Fellows, Stanford University, CA, October 22, 2010.

“Sleep medicine at Stanford.” Otolaryngology Grand Rounds, Stanford Department of Otolaryngology – Head & Neck Surgery, Stanford University, CA, October 7, 2010.

“Basic mechanisms of sleep.” Sleep Disorders, Physiology of Sleep, and Chronobiology: Clinical Review for Sleep Medicine Attending Physicians and Clinical Fellows, Stanford University, CA, August 6, 2010.

“Sleep Disorders.” Menlo Medical Clinic, Menlo Park, CA, July 13, 2010. “Pharmacology of major sleep disorders.” Psychopharmacology Update 2010, Northern California

Psychiatric Society, The Great Hall, San Francisco Zoo, San Francisco, CA, June 12, 2010. “Parasomnias.” Sleep and Dreams Course for Undergraduate students (PSYC 135), Stanford University,

CA, April 30, 2010. “Sleep disorders diagnosis.” Psychiatry Residency Training Program, San Mateo County Behavioral

Health and Recovery Services, San Mateo Medical Center, San Mateo, CA, April 6, 2010. “Management of obstructive sleep apnea: Oral appliance therapy.” California Society of Dental Sleep

Medicine Meeting, Pebble Beach, CA, February 13, 2010. “Management of obstructive sleep apnea.” Lecture to Medical Students during Course on Obesity,

Stanford University, February 11, 2010. “Parasomnias.” Sleep and Dreams Course for Undergraduate students (PSYC 135), Stanford University,

CA, February 5, 2010. “Treating common sleep problems.” Stanford University Outreach Program, San Jose, CA, January 12,

2010. “Restless legs syndrome and periodic limb movement disorder.” Clinical Review for Sleep Medicine

Attending Physicians and Clinical Fellows, Stanford University, CA, December 4, 2009.

Clete A. Kushida, M.D., Ph.D., RPSGT 40

“Common sleep problems, Part 2.” Yahoo, Sunnyvale, CA, December 3, 2009. “Presidential address.” The 2nd Educational Meeting of the California Sleep Society, Burlingame, CA,

November 14, 2009. “Sleep disorders and sleep apnea: Diagnosis and management.” Obstructive Sleep Apnea: The

Ramifications of Sleepiness and State-of-the-Art Management and Treatment, Center for Education and Professional Development, Division of Patient Care Services, Stanford University, CA, November 4, 2009.

“Common sleep problems, Part 1.” Yahoo, Sunnyvale, CA, October 7, 2009. “Advances in OSA treatment.” Focus on Complex Care for Case Managers, Stanford Medicine Outpatient

Center, CA, September 23, 2009. “Apnea positive pressure long-term efficacy study (APPLES)” Sleep Grand Rounds, Stanford University,

CA, September 11, 2009. “Basic mechanisms of sleep.” Sleep Disorders, Physiology of Sleep, and Chronobiology: Clinical Review

for Sleep Medicine Attending Physicians and Clinical Fellows, Stanford University, CA, July 31, 2009. “Sleep disorders and their treatment in the elderly.” Geropsychiatry Seminar Series, Department of

Psychiatry and Behavioral Sciences, Stanford University, CA, July 23, 2009. “The future of sleep medicine.” School of Sleep Medicine, Palo Alto, CA, July 16, 2009. “Obstructive sleep apnea.” Preventive Cardiology Seminar, Stanford University, June 23, 2009. “Restless legs syndrome and periodic limb movement disorder.” Clinical Review for Sleep Medicine

Attending Physicians and Clinical Fellows, Stanford University, CA, April 24, 2009. “Obstructive sleep apnea – The ramifications of sleepiness and state of the art management and

treatment. Nursing Grand Rounds, Stanford University, CA, April 1, 2009. “Evidence-based medicine.” Sleep Surgical Conference, Stanford University, CA, March 6, 2009. “Management of obstructive sleep apnea.” Lecture to Medical Students during Course on Obesity,

Stanford University, March 5, 2009. “Insomnia and psychopharmacology of sleep disorders-II.” PGY-III Advanced Psychopharmacology

Course, Department of Psychiatry and Behavioral Sciences, Stanford University, March 5, 2009. “Insomnia and psychopharmacology of sleep disorders-I.” PGY-III Advanced Psychopharmacology

Course, Department of Psychiatry and Behavioral Sciences, Stanford University, February 26, 2009. “Parasomnias.” Sleep and Dreams Course for Undergraduate students (PSYC 135), Stanford University,

CA, February 6, 2009. “Presidential address.” Inaugural Educational Meeting of the California Sleep Society, La Jolla, CA,

November 22, 2008. “Obstructive sleep apnea.” Department of Respiratory Care, Stanford University Medical Center, CA,

October 16, 2008. “American Academy of Sleep Medicine position on portable monitoring.” California Technology

Assessment Forum, San Francisco, CA, October 15, 2008. “Common sleep problems.” Fall 2008 Epidemiology Research Seminar Series (HRP 236), Stanford

University, CA, October 7, 2008. “Common sleep disorders.” Lecture to Faculty and Staff at Stanford Family Practice and Internal Medicine,

Stanford University, CA, September 25, 2008. “Restless legs syndrome treatment options” and “Other sleep problems that may occur with restless legs

syndrome.” Restless Legs Syndrome Foundation Regional Meeting, San Francisco, CA, August 23, 2008.

“Common sleep disorders.” Wellness Week Lecture, Google, Mountain View, CA, August 14, 2008. “Common sleep disorders.” Lecture to Faculty and Staff at the Menlo Medical Clinic, Menlo Park, CA,

August 4, 2008. “California Senate Bill 1526: Polysomnographic technologists: Sleep and wake disorders.” Medical Board

of California Meeting, South San Francisco, CA, July 25, 2008. “Sleep disorders and their treatment in the elderly.” Geropsychiatry Seminar Series, Department of

Psychiatry and Behavioral Sciences, Stanford University, CA, July 24, 2008. “Basic mechanisms of sleep.” Sleep Disorders, Physiology of Sleep, and Chronobiology: Clinical Review

for Sleep Medicine Attending Physicians and Clinical Fellows, Stanford University, CA, July 18, 2008. “Pain and sleep.” Lecture for Pain Medicine Faculty and Fellows, Stanford University, CA, July 14, 2008. “Movement and cardiac rules: AASM Scoring Manual (2007).” Technologist Polysomnographic Scoring

Review, Stanford University, CA, June 26, 2008. “Visual and arousal rules: AASM Scoring Manual (2007).” Technologist Polysomnographic Scoring

Review, Stanford University, CA, June 25, 2008.

Clete A. Kushida, M.D., Ph.D., RPSGT 41

“Sleep and pain.” Pain Medicine Lecture Series, Stanford University, CA, July 14, 2008. “Sleep and its disorders.” Basic Core Psychiatry Clerkship Lecture for Medical Students (PSYC 300A),

Stanford University, June 3, 2008. “Common sleep problems.” Research Meeting, ARYx Therapeutics, Fremont, CA, April 28, 2008. “California Senate Bill 1526: Polysomnographic technologists: Sleep and wake disorders.” Medical Board

of California Meeting, Sacramento, CA, April 25, 2008. “Restless legs syndrome: Diagnosis and treatment.” Restless Legs Syndrome Patient Support Group

Meeting, Community Hospital of the Monterey Peninsula, Monterey, CA, April 19, 2008. “California Senate Bill 1526: Polysomnographic technologists: Sleep and wake disorders.” California

Legislature 2007-8 Regular Session, Sacramento, CA, April 14, 2008. “Evidence-based medicine.” Sleep Surgical Conference, Stanford University, CA, March 1, 2008. “Using and scoring actigraphy.” Sleep Disorders, Physiology of Sleep, and Chronobiology: Clinical Review

for Sleep Medicine Attending Physicians and Clinical Fellows, Stanford University, CA, February 21, 2008.

“Parasomnias.” Sleep and Dreams Course for Undergraduate students (PSYC 135), Stanford University, CA, February 15, 2008.

“Laser-assisted uvulopalatoplasty.” Sleep Surgical Conference, Stanford University, CA, February 1, 2008.

“Sleep and its disorders.” Basic Core Psychiatry Clerkship Lecture for Medical Students (PSYC 300A), Stanford University, October 30, 2007.

“Apnea positive pressure long-term efficacy study (APPLES)” and “Apnea positive pressure long-term efficacy cardiovascular outcomes research study (APPLE CORS).” Research Symposium, Stanford University, CA, September 17, 2007.

“Restless legs syndrome and periodic limb movement disorder.” Clinical Review for Polysomnographic Technologists, Stanford University, CA, July 20, 2007.

“Basic mechanisms of sleep.” Sleep Disorders, Physiology of Sleep, and Chronobiology: Clinical Review for Sleep Medicine Attending Physicians and Clinical Fellows, Stanford University, CA, July 6, 2007.

“Restless legs syndrome” and “Apnea positive pressure long-term efficacy study (APPLES).” Research Symposium, Stanford University, CA, June 25, 2007.

“Sleep and its disorders.” Basic Core Psychiatry Clerkship Lecture for Medical Students (PSYC 300A), Stanford University, May 15, 2007.

“Parasomnias.” Sleep Disorders, Physiology of Sleep, and Chronobiology: Clinical Review for Sleep Medicine Attending Physicians and Clinical Fellows, Stanford University, CA, May 4, 2007.

“Sleep and its disorders.” Otolaryngology Grand Rounds, Stanford University, CA, April 5, 2007. “Sleep medicine.” Principles of Sleep Research Course (Human Biology 124, Biological Sciences

149/249), Stanford University, CA, March 8, 2007. “Sleep disorder testing: Actigraphy, MSLT, and MWT.” Sleep Disorders, Physiology of Sleep, and

Chronobiology: Clinical Review for Sleep Medicine Attending Physicians and Clinical Fellows, Stanford University, CA, February 16, 2007.

“Parasomnias.” Sleep and Dreams Course for Undergraduate students (PSYC 135), Stanford University, CA, February 14, 2007.

“Treatment of restless legs syndrome and periodic limb movement disorder.” Sleep Disorders, Physiology of Sleep, and Chronobiology: Clinical Review for Sleep Medicine Attending Physicians and Clinical Fellows, Stanford University, CA, January 19, 2007.

“Evidence-based medicine.” Sleep Disorders, Physiology of Sleep, and Chronobiology: Clinical Review for Sleep Medicine Attending Physicians and Clinical Fellows, Stanford University, CA, January 2, 2007.

“Sleep and its disorders.” Palo Alto Research Center (PARC), Palo Alto, CA, December 21, 2006. “Diagnosis of restless legs syndrome and periodic limb movement disorder.” Sleep Disorders, Physiology

of Sleep, and Chronobiology: Clinical Review for Sleep Medicine Attending Physicians and Clinical Fellows, Stanford University, CA, November 17, 2006.

“Sleep disorders.” Otero Dormitory, Stanford University, CA, October 25, 2006. “Sleep disorders.” Okada Dormitory, Stanford University, CA, October 18, 2006. “Apnea positive pressure long-term efficacy study (APPLES).” Sleep Grand Rounds, Stanford University,

CA, September 22, 2006. “Restless legs, restless nights: Putting restless legs syndrome to bed.” Pri-Med Updates Meeting, South

San Francisco, CA, September 21, 2006. “Neurocognitive evaluation of sleep apnea patients.” Speaker, XenoPort Meeting, Santa Clara, CA,

September 20, 2006.

Clete A. Kushida, M.D., Ph.D., RPSGT 42

“Surgeon fatigue and sleep loss.” Plastic and Reconstructive Surgery Grand Rounds, Stanford University, CA, August 23, 2006.

“Common sleep disorders.” Neurology Grand Rounds, University of California, San Diego, CA, August 11, 2006.

“Sleep and its disorders.” Basic Core Psychiatry Clerkship Lecture for Medical Students (PSYC 300A), Stanford University, August 8, 2006.

“Basic sleep mechanisms.” Sleep Disorders, Physiology of Sleep, and Chronobiology: Clinical Review for Sleep Medicine Attending Physicians and Clinical Fellows, Stanford University, CA, August 4, 2006.

“Sleep and surgeon fatigue.” Otolaryngology Lecture, Stanford University, CA, July 27, 2006. “CME cafe: Cooking up strategies for movement disorders and epilepsy.” Intellyst CME Primary Care

Meetings, Santa Barbara, CA (June 7, 2006), San Jose, CA (June 28, 2006). “Clinical applications of brainwave entrainment to external stimuli.” Roundtable discussion of Brainwave

Entrainment to External Rhythmic Stimuli: Interdisciplinary Research and Clinical Perspectives, Center for Computer Research in Music and Acoustics (CCRMA), Stanford University, CA, May 13, 2006.

“Neurocognitive testing in sleep disorders.” Scientific review meeting, XenoPort, Inc., Santa Clara, CA, May 11, 2006.

“Parasomnias.” VA-Stanford Pulmonary Grand Rounds, VA Palo Alto Health Care System, Palo Alto, CA, May 5, 2006.

“Sleep and its disorders.” Basic Core Psychiatry Clerkship Lecture for Medical Students (PSYC 300A), Stanford University, May 2, 2006.

“Restless legs syndrome and periodic limb movement disorder.” Sleep Disorders, Physiology of Sleep, and Chronobiology: Clinical Review for Sleep Medicine Attending Physicians and Clinical Fellows, Stanford University, CA, April 28, 2006.

“Parasomnias.” Sleep Disorders, Physiology of Sleep, and Chronobiology: Clinical Review for Sleep Medicine Attending Physicians and Clinical Fellows, Stanford University, CA, April 28, 2006.

“Chez CME: Appetizing courses on restless legs syndrome and sleep disorders.” Intellyst CME Primary Care Meetings, San Francisco, CA (April 27, 2006), San Jose, CA (June 28, 2006), Sacramento, CA (July 12, 2006), Orange County, CA (September 28, 2006).

“Restless legs, restless nights: Putting restless legs syndrome to bed.” Pri-Med Updates Meeting, San Diego, CA, April 12, 2006.

“Laser-assisted uvulopalatoplasty.” Sleep Surgical Conference, Stanford University, CA, March 3, 2006. “Apnea positive pressure long-term efficacy study (APPLES).” Pulmonary conference, Santa Clara Valley

Medical Center, CA, March 1, 2006. “Parasomnias.” Sleep and Dreams Course for Undergraduate students (PSYC 135), Stanford University,

CA, February 22, 2006. “Latest updates from sleep apnea research.” AWAKE (Alert, Well, And Keeping Energetic obstructive

sleep apnea patient support group) Meeting, Stanford, CA, February 1, 2006. “Cine-MRI evaluation of the upper airway.” Anesthesia Research Meeting, Stanford University, CA,

December 15, 2005. “Parasomnias.” VA-Stanford Pulmonary Grand Rounds, VA Palo Alto Health Care System, Palo Alto, CA,

October 28, 2005. “Sleep and its disorders.” Basic Core Psychiatry Clerkship Lecture for Medical Students (PSYC 300A),

Stanford University, October 25, 2005. “Apnea positive pressure long-term efficacy study (APPLES).” Sleep Grand Rounds, Stanford University,

CA, September 16, 2005. “Neuroanatomy and neurophysiology of sleep.” Sleep Disorders, Physiology of Sleep, and Chronobiology:

Clinical Review for Sleep Medicine Attending Physicians and Clinical Fellows, Stanford University, CA, August 12, 2005.

“Sleep and its disorders.” Basic Core Psychiatry Clerkship Lecture for Medical Students (PSYC 300A), Stanford University, August 2, 2005.

“Update on sleep research.” Clinical Review for Sleep Medicine Attending Physicians and Clinical Fellows, Stanford University, CA, July 29, 2005.

“Common sleep problems.” Neurology Residents Teaching Conference, Stanford University, CA, May 11, 2005.

“Restless legs syndrome and periodic limb movement disorder.” Psychiatry residents lecture, Stanford University, CA, May 5, 2005.

Clete A. Kushida, M.D., Ph.D., RPSGT 43

“Basic sleep mechanisms.” Sleep Disorders, Physiology of Sleep, and Chronobiology: Clinical Review for Sleep Medicine Attending Physicians and Clinical Fellows, Stanford University, CA, February 11, 2005.

“Sleep and its disorders.” Stanford Continuing Studies Lecture to the Stanford community, Stanford University, CA, February 5, 2005.

“Laser-assisted uvulopalatoplasty.” Sleep Surgical Conference, Stanford University, CA, February 4, 2005.

“Sleep apnea and cardiovascular disease.” Case Presentation and Lecture in conjunction with Patricia Nguyen, M.D., Cardiovascular Medicine, Division Clinical Conference, Stanford University, CA, January 7, 2005.

“Investigating movement disorders: Food for thought.” Intellyst CME Primary Care Meetings, San Jose, CA (January 31, 2005), Sacramento, CA (February 7, 2005), Santa Ana, CA (March 10, 2005).

“Restless legs syndrome and periodic limb movement disorder.” Clinical Review for Polysomnographic Technologists, Stanford University, CA, December 3, 2004.

“Sleep and its disorders.” Basic Core Psychiatry Clerkship Lecture for Medical Students (PSYC 300A), Stanford University, November 23, 2004.

“Sleeping difficulties.” Lecturer, APPLE Computer Seminar, Cupertino, CA, November 4, 2004. “Restless legs, restless nights: Innovations in the treatment of RLS.” Pri-Med Updates Meeting, San

Francisco, CA, October 15, 2004. “Tonight’s special: Discussion on movement disorders.” Intellyst CME Primary Care Meetings, San Jose,

CA (September 27, 2004), Santa Ana, CA (October 7, 2004), Sacramento, CA (October 25, 2004), Los Angeles, CA (November 18, 2004).

“Restless legs syndrome and periodic limb movement disorder.” Sleep Disorders, Physiology of Sleep, and Chronobiology: Clinical Review for Sleep Medicine Attending Physicians and Clinical Fellows, Stanford University, CA, September 17, 2004.

“Sleep disorders.” Lecturer, Stanford Medical Youth in Science Program Workshop, Stanford University, CA, July 2, 2004.

“Sleepwalking and other parasomnias.” Clinical Review for Polysomnographic Technologists, Stanford University, CA, March 19, 2004.

“Laser-assisted uvulopalatoplasty.” Sleep Surgical Conference, Stanford University, CA, March 5, 2004. “Restless legs syndrome and periodic limb movement disorder.” Sleep Disorders, Physiology of Sleep,

and Chronobiology: Clinical Review for Sleep Medicine Attending Physicians and Clinical Fellows, Stanford University, CA, February 27, 2004.

“Sleep medicine.” Introductory Psychiatry Course for Medical Students (PSYC 201), Stanford University, February 23, 2004.

“Sleep and its disorders.” Basic Core Psychiatry Clerkship Lecture for Medical Students (PSYC 300A), Stanford University, February 10, 2004.

“Sleep disorders and aging.” Principles of Sleep Research Course (Human Biology 124, Biological Sciences 149/249), Stanford University, CA, February 4, 2004.

“Restless legs syndrome and periodic limb movement disorders.” Psychiatry residents lecture, Stanford University, CA, January 22, 2004.

“Snoring and sleep apnea.” Stanford Pediatrics Allergy and Clinical Immunology Conference, Stanford University, CA, January 8, 2004.

“Sleep and its disorders.” Basic Core Psychiatry Clerkship Lecture for Medical Students (PSYC 300A), Stanford University, November 25, 2003.

“Basic mechanisms: Neuroanatomy and neurophysiology of sleep.” Sleep Disorders, Physiology of Sleep, and Chronobiology: Clinical Review for Sleep Medicine Attending Physicians and Clinical Fellows, Stanford University, CA, October 31, 2003.

“Get some sleep without counting sheep.” Lecture on narcolepsy, obstructive sleep apnea, and restless legs syndrome at the Los Angeles Times Festival of Health and Fitness, October 4, 2003.

“Restless legs syndrome.” Clinical Review for Polysomnographic Technologists, Stanford University, CA, August 15, 2003.

“Sleep disorders.” Lecturer, Stanford Medical Youth in Science Program Workshop, Stanford University, CA, July 11, 2003.

“Apnea positive pressure long-term efficacy study (APPLES)” Sleep Grand Rounds, Stanford University, CA, May 30, 2003.

“Sleep.” Biomedical Informatics Research Colloquium, Stanford University, CA, May 22, 2003.

Clete A. Kushida, M.D., Ph.D., RPSGT 44

“Sleep and its disorders.” Basic Core Psychiatry Clerkship Lecture for Medical Students (PSYC 300A), Stanford University, May 6, 2003.

“Neuroanatomy of sleep.” Sleep Disorders, Physiology of Sleep, and Chronobiology: Clinical Review for Sleep Medicine Attending Physicians and Clinical Fellows, Stanford University, CA, April 25, 2003.

“Periodic limb movement disorder and restless legs syndrome.” Speaker, “Steadying the Course of Movement Disorders”, Pri-Med West 2003 Meeting, Long Beach, California, April 2, 2003.

“Effectiveness of continuous positive airway pressure for obstructive sleep apnea.” AWAKE (Alert, Well, And Keeping Energetic obstructive sleep apnea patient support group) Meeting, Stanford, CA, March 5, 2003.

“Parasomnias.” Sleep and Dreams Course for Undergraduate students (PSYC 135), Stanford University, CA, March 3, 2003.

“Sleep medicine.” Introductory Psychiatry Course for Medical Students (PSYC 201), Stanford University, February 24, 2003.

“Laser-assisted uvulopalatoplasty.” Sleep Surgical Conference, Stanford University, CA, December 2002. “Common sleep disorders.” Physician Assistant/Nurse Practitioner Seminar, Primary Care Associate

Program, Department of Medicine, Stanford University Medical Center, Stanford University, CA, November 2002.

“Diagnosis and management of restless legs syndrome.” Speaker, Exploring the Management of Parkinson’s Disease and Restless Legs Syndrome Meeting, The Center for Health Care Education Regional CME Meeting, Los Angeles, CA, October 11, 2002.

“Restless legs syndrome.” Kaiser Permanente Restless Legs Syndrome Support Group, Walnut Creek, CA, September 2002.

“Overview of Sleep Medicine.” Pulmonary and Sleep Medicine Seminar, VA Palo Alto Health Care System, Palo Alto, CA, September 17, 2002.

“Sleep and its disorders.” Basic Core Psychiatry Clerkship Lecture for Medical Students (PSYC 300A), Stanford University, August 27, 2002.

“Restless legs syndrome and periodic limb movement disorder.” AWAKE (Alert, Well, And Keeping Energetic obstructive sleep apnea patient support group) Meeting, Stanford, CA, June 2002.

“Restless and periodic leg movement syndromes.” Pulmonary and Sleep Medicine Seminar, VA Palo Alto Health Care System, Palo Alto, CA, April 2002.

“New findings in the diagnosis and management of restless legs syndrome and periodic limb movement disorders.” Sleep Grand Rounds, Stanford University, CA, April 2, 2002.

“Introduction to sleep disorders.” Neurology Residents’ Seminar, Stanford University Medical Center, Stanford University, CA, March 2002.

“Actigraphy.” Sleep Disorders, Physiology of Sleep, and Chronobiology: Clinical Review for Sleep Medicine Attending Physicians and Clinical Fellows, Stanford University, CA, March 2002.

“New findings in the diagnosis and management of restless legs syndrome and periodic limb movement disorder.” Neurology Residents’ Seminar, Stanford University Medical Center, Stanford University, CA, March 2002.

“Parasomnias.” Sleep and Dreams Course for Undergraduate students (PSYC 135), Stanford University, CA, March 4, 2002.

“Sleep and its disorders.” Basic Core Psychiatry Clerkship Lecture for Medical Students (PSYC 300A), Stanford University, February 5, 2002.

“Sleep medicine.” Introductory Psychiatry Course for Medical Students (PSYC 201), Stanford University, February 4, 2002.

“Restless legs syndrome/Periodic limb movement disorder.” Sleep Disorders, Physiology of Sleep, and Chronobiology: Clinical Review for Sleep Medicine Attending Physicians and Clinical Fellows, Stanford University, CA, January 2002.

“Basic mechanisms of normal and abnormal sleep.” Pulmonary and Sleep Medicine Seminar, VA Palo Alto Health Care System, Palo Alto, CA, November 2001.

“Sleep and its disorders.” Basic Core Psychiatry Clerkship Lecture for Medical Students (PSYC 300A), Stanford University, July 31, 2001.

“Common sleep disorders: Diagnosis and management.” Department of Pediatrics Grand Rounds, Mattel Children’s Hospital at University of California at Los Angeles (UCLA), CA, April 27, 2001.

“Sleep disorders.” Nikken Seminar, Fremont, CA, March 24, 2001. “Parasomnias.” Sleep and Dreams Course for Undergraduate students (PSYC 135), Stanford University,

CA, March 7, 2001.

Clete A. Kushida, M.D., Ph.D., RPSGT 45

“Sleep and its disorders.” Basic Core Psychiatry Clerkship Lecture for Medical Students (PSYC 300A), Stanford University, March 6, 2001.

“Sleep medicine.” Introductory Psychiatry Course for Medical Students (PSYC 201), Stanford University, February 12, 2001.

“Restless legs syndrome and periodic limb movement disorder.” The Vast Terrain of Sleep and Its Disorders: A Challenge for the New Millennium, Community Forum, Stanford University School of Medicine, Stanford University, CA, January 2001.

“Apnea Positive Pressure Long-Term Efficacy Study (APPLES): Results from preliminary study.” Sleep Grand Rounds, Stanford University, CA, December 2000.

“Basic mechanisms of normal and abnormal sleep.” Pulmonary and Sleep Medicine Seminar, VA Palo Alto Health Care System, Palo Alto, CA, October 2000.

“Restless legs syndrome and periodic limb movement disorder.” Neurology Grand Rounds, University of California at Davis, CA, July 27, 2000.

“Sleepwalking and associated sleep disorders.” Sleep Seminar, University of California at San Francisco (Langley Porter), CA, June 2000.

“Mortality and sleep apnea.” Speaker, Risk Appraisal Forum Meeting, San Francisco, CA, April 1, 2000. “Actigraphy.” Sleep Surgical Conference, Stanford University, CA, March 2000. “Parasomnias.” Sleep and Dreams Course for Undergraduate students (PSYC 135), Stanford University,

CA, February 23, 2000. “Sleep medicine.” Introductory Psychiatry Course for Medical Students (PSYC 201), Stanford University,

January 10, 2000. “Restless legs syndrome and periodic limb movement disorder.” Sleep Medicine Grand Rounds, Stanford

University Medical Center, Stanford University, CA, December 1999. “Approach to a patient with sleep complaints.” Neurology Residents’ Seminar, Stanford University Medical

Center, Stanford University, CA, November 1999. “Common sleep disorders: Diagnosis and management.” Neurology Grand Rounds, Stanford University

Medical Center, Stanford University, CA, November 1999. “Sleep and its disorders.” Basic Core Psychiatry Clerkship Lecture for Medical Students (PSYC 300A),

Stanford University, CA, November 16, 1999. “Sleep disorders.” Stanford Help Center, Stanford University, CA, September 1999. “Always tired: Obstructive sleep apnea.” Stanford University Health Library Community Health Series,

Stanford, CA, August 1999. “Basic sleep mechanisms.” Lecturer, School of Sleep Medicine, Palo Alto, CA, August 26, 1999. “Diagnosis and management of restless legs syndrome.” Mt. Diablo Medical Center Seminar, Lafayette,

CA, August 17, 1999. “Sleep and its disorders.” Rotary Club, Burlingame, CA, August 1999. “Sleep and its disorders.” Basic Core Psychiatry Clerkship Lecture for Medical Students (PSYC 300A),

Stanford University, June 29, 1999. “Pain and sleep.” Anesthesiology Grand Rounds, Stanford University Medical Center, Stanford University,

CA, June 1999. “Obstructive sleep apnea syndrome.” Managing Sleep Disorders Course, UCSF Stanford Health Care

Center for Education, Stanford, CA, March 1999. “Non-conventional approaches for treatment of sleep disorders.” Sleep Grand Rounds, Stanford

University, CA, March 1999. “Parasomnias.” Sleep and Dreams Course for Undergraduate students (PSYC 135), Stanford University,

CA, March 3, 1999. “Sleep and its disorders.” Basic Core Psychiatry Clerkship Lecture for Medical Students (PSYC 300A),

Stanford University, March 2, 1999. “Cervical positioning and obstructive sleep apnea.” Sleep Conference, Stanford University, CA, March

1999. “Cervical positioning and obstructive sleep apnea.” Life Sleep Systems Medical Advisory Board Meeting,

San Francisco, CA, February 1999. “Sleep apnea.” Medical Staff CME Program, Saint Louise Hospital, Morgan Hill, CA, November 17, 1998. “Sleep problems.” Stanford Alumni Club, San Ramon, CA, November 1998. “Sleep disorders.” Community Health Resources Center, California Pacific Medical Center, San Francisco,

CA, November 4, 1998. “Sleep and its disorders.” Basic Core Psychiatry Clerkship Lecture for Medical Students (PSYC 300A),

Stanford University, October 20, 1998.

Clete A. Kushida, M.D., Ph.D., RPSGT 46

“Cellular and non-cellular telephone EMF and sleep.” Sleep Surgical Conference, Stanford University, CA, September 1998.

“Sleep problems in the elderly.” Nikkei Retirement Home, San Francisco, CA, September 1998. “Restless legs syndrome and periodic limb movement disorder.” Sleep Surgical Conference, Stanford

University, CA, July 1998. “Sleep and its disorders.” Basic Core Psychiatry Clerkship Lecture for Medical Students (PSYC 300A),

Stanford University, July 28, 1998. “Common sleep problems.” Community Health Resources Center, California Pacific Medical Center, San

Francisco, CA, May 1998. “Standardizing the hypopnea.” Sleep Surgical Conference, Stanford University, CA, May 1998. “Adverse impact of sleepiness on health and safety.” Medical Education Conference, Torrance Memorial

Medical Center, Torrance, CA, January 28, 1998. “Obstructive sleep apnea.” Biostatistics Seminar Series, Stanford University, CA, October 1997. “Clinical models of sleep apnea." Clinical Seminar Series on Sleep, Stanford University, CA, August 1997. “Neurophysiology of sleep.” Clinical Seminar Series on Sleep, Stanford University, CA, August 1997. “Insomnia.” Anesthesiology Grand Rounds, Stanford University Medical Center, Stanford University, CA,

April 1997. “Obstructive sleep apnea.” Medicine Grand Rounds, San Joaquin General Hospital, San Joaquin, CA,

April 1997. “Obstructive sleep apnea." Rotary Club, Los Altos, CA, April 1997. “Recent developments in the pathogenesis of obstructive sleep apnea.” Sleep and Biological Rhythms

Seminar Series, University of California, San Diego, CA, January 1997. “Snoring and sleep apnea.” Stanford Help Center, Stanford University, CA, October 1996. “New treatments for the restless legs syndrome and periodic limb movement disorder.” Meeting of the

Northern California Chapter of the Restless Legs Syndrome Foundation, Palo Alto, CA, September 1996.

“Basic sleep mechanisms.” Clinical Seminar Series on Sleep, Stanford University, CA, September 1996. “Sleepwalking: Clinical features and legal implications.” CME Program, Napa State Hospital, Napa, CA,

May 2, 1996. “Assembly Bill 2862: In-home medical care for technology-dependent children.” California Legislature

1995-96 Regular Session, Sacramento, CA, April - June 1996. “SleepLinkTM: An interactive linked computer program for sleep data analysis.” Sleep Grand Rounds,

Stanford University, CA, December 1995. “Sleep and dementia.” Alzheimers Support Group, Los Altos, California, November 1995. “Restless legs syndrome and periodic limb movement disorder.” Meeting of the Northern California

Chapter of the Restless Legs Syndrome Foundation, San Francisco, CA, September 1995. “A predictive morphometric model for obstructive sleep apnea.” Sleep Grand Rounds, Stanford

University, CA, August 1995. “Obstructive sleep apnea and daytime sleepiness.” Rotary Club, San Jose, CA, July 1995. “Morphometric models and genetic patterns in the obstructive sleep apnea syndrome.” AWAKE (Alert,

Well, And Keeping Energetic obstructive sleep apnea patient support group) Meeting, Stanford, CA, June 1995.

“Obstructive sleep apnea.” Grand Rounds, Temple Community Hospital, Los Angels, CA, March 1995. “Sites of obstruction and utility of clinical measurements of the upper airway.” Clinical Seminar Series on

Sleep, Stanford University, CA, February 1994. “The effects of REM sleep deprivation in rats.” Sleep Grand Rounds, Stanford University, CA, December

1994. “Expression of m3 muscarinic receptor mRNA with REM sleep deprivation.” Chronobiology and Sleep

Seminar Series, University of California, San Diego, CA, June 1994. “Spastic paraparesis.” Neurology Grand Rounds, University of California, San Diego, CA, November

1993. “Expression of m1 muscarinic receptor mRNA with REM sleep deprivation.” Chronobiology and Sleep

Seminar Series, University of California, San Diego, CA, June 1993. “Physiological effects of REM sleep deprivation in rats.” Chronobiology and Sleep Seminar Series,

University of California, San Diego, CA, December 1992. “Cerebral P. carinii associated with AIDS.” Neurology Grand Rounds, San Diego, California, September

1991.

Clete A. Kushida, M.D., Ph.D., RPSGT 47

Web Conferences

“Oral appliances.” American Association of Sleep Technologists (AAST) Journal Club, June 12, 2014. “Comparative Outcomes Management with Electronic Data Technology (COMET) Study.” Electronic Data

Methods (EDM) Forum Virtual Brown Bag Webinar, July 10, 2013. “Effects of Continuous Positive Airway Pressure on Neurocognitive Function in Obstructive Sleep Apnea

Patients: The Apnea Positive Pressure Long-term Efficacy Study (APPLES).” Sleep and Respiratory Neurobiology Journal Club, American Thoracic Society, June 11, 2013.

“The Apnea Positive Pressure Long-term Efficacy Study (APPLES).” American Association of Sleep Technologists (AAST) Journal Club, January 16, 2013.

“Strategies for de-identification and anonymization of electronic health record data for use in multicenter research studies.” Protecting Human Subjects and Their Data in Multi-site Research, Electronic Data Management Forum Webinar, August 16, 2012.

“Sleep and common sleep problems.” Stanford University Health Improvement Program, Stanford University, CA, August 13, 2012.

“Practical strategies in the diagnosis and management of sleep disorders.” Problem-Based Learning CME Webconference, July 6, 2008, July 10, 2008, August 7, 2008, August 13, 2008.

“Differentiating leg disorders: Understanding impact and improving patient outcomes.” Webinars, Biology of Leg Disorders (BOLD) CME Audio/Webeconferences, October 11, 2007, October 24, 2007, November 15, 2007, November 29, 2007.

“Hypersomnias.” Webinar, American Academy of Sleep Medicine, May 23, 2007. “Narcolepsy.” CME Web Workshop, January 24, 2007. “Movement disorders.” Webinar, Biology of Leg Disorders (BOLD) CME Audio/Webeconference, August

31, 2006, November 2, 2006. Visiting Professorships

“Apnea positive pressure long-term efficacy study (APPLES).” 2009 Visiting Professorship, Scripps Memorial Hospital, La Jolla, CA, May 29, 2009.

“Apnea positive pressure long-term efficacy study (APPLES).” 2008 Visiting Lecturer, University of Pittsburgh Medical Center, Pittsburgh, PA, May 29, 2008.

Clete A. Kushida, M.D., Ph.D., RPSGT 48

ATTACHMENT 1

GRANTS

Active

PCORI CE-12-11-4137 (Kushida - PI) 9/30/13 - 9/29/16 SMART DOCS (Sustainable Methods, Algorithms, and Research Tools for Delivering Optimal Care Study) Specific Aim 1: To develop a patient-centered outcomes and coordinated-care management (PCCM) approach for sleep medicine enabling providers and patients access to specific and relevant information and resources, thereby allowing patients to make informed health care decisions and providers to assist patients in achieving their preferred outcomes. Specific Aim 2: To conduct a randomized trial that will test the PCCM approach for sleep medicine against a conventional diagnostic/treatment outpatient medical care approach with assessment of patient satisfaction and perception of care. PAIRE (PI – Yesavage PI / Kushida – Co-Investigator) 7/1/13 - 6/30/18 Treatments for Insomnia, Mediators, Moderators and Quality of Life A randomized clinical trial to evaluate the relative efficacy and effectiveness of specific components of CBT-I: sleep restriction (SR) and cognitive therapy (CT) in comparison to combined SR and CT (SR+CT). NIH/NHLBI R01 HL114529-01 (Ong PI / Kushida Consultant) 7/1/12 - 6/30/17 Multidisciplinary Treatment for Obstructive Sleep Apnea and Insomnia The purpose of this research project is to determine the efficacy of a multidisciplinary treatment model for patients with OSA and comorbid insomnia. The specific aims are to determine the efficacy of a treatment model combining CBT and CPAP for individuals with OSA and comorbid insomnia and to determine if there are relative benefits in the sequence of treatment initiation. RFA-HL-11-005 (PI – Reaven / Kushida – Co-Investigator) 7/1/11 - 6/30/15 Sleep Apnea, Type 2 Diabetes and CVD: a Cluster Related to Insulin Resistance Completed

Contract (Kushida - PI) 7/6/11 - 6/30/14 ResMed Corporation Effectiveness of Adaptive Servoventilation (ASV) in Patients with Central Sleep Apnea due to Chronic Opioid Use. Resmed (Kushida - PI) Effectiveness of Adaptive Servoventilation (ASV) in Patients with Central Sleep Apnea due to Chronic Opioid Use.

Jawbone Corp (Kushida – PI) 9/1/13 – 8/31/14 A joint JAWBONE/Stanford Sleep Stage Detection Experiment Contract (Kushida –PI) 12/20/12 - 12/31/14 Cephalon A Randomized, Open-Label Study to Characterize the Pharmacokinetics, Pharmacodynamics, and Safety of Single and Multiple Doses of Armodafinil (50, 100 and 150mg/day) in Children and Adolescents with Excessive Sleepiness Associated with Narcolepsy. Aerial BioPharma (Kushida – PI) 1/30/13 - 12/31/14 Safety and efficacy of ADX-N05 in the treatment of excessive daytime sleepiness in subjects with narcolepsy Contract (Kushida PI) 6/14/12 - 6/30/14 Impax Laboratories, Inc. IPX159: A Randomized, Double-Blind, Placebo-Controlled Safety and Efficacy Study of IPX159 in the Treatment of Moderate to Severe Restless Legs Syndrome (RLS). AHRQ 1R01HS019738-01 (Kushida - PI) 9/30/10 - 9/29/13 COMET (Comparative Outcomes Management with Electronic Data Technology)

Clete A. Kushida, M.D., Ph.D., RPSGT 49

The purpose of this study will be to develop an electronic network informatics infrastructure that will enable the transfer of information from various hospitals and medical centers, patients and research subjects, different types and severity of medical problems, various equipment and test types, and across several patient visits. This network will allow physicians and scientists to access comprehensive information about their patients and research subjects, and the sharing of this information across several academic institutions (initially at Stanford University, Harvard University, University of Pennsylvania, and University of Wisconsin-Madison) may ultimately lead to improvement in medical outcomes. As part of the COMET Study, we also plan to conduct a trial evaluating two common treatments for obstructive sleep apnea (OSA), CPAP and oral appliances, and we anticipate that this study will provide comparative data for determining the effectiveness of these treatments in reducing cardiovascular risk in a population at high risk for cardiovascular disease, and will enhance clinical decision making in determining the optimal treatment strategies for patients with OSA. Contract (Kushida – PI) 9/1/10 - 6/30/13 Pacific Medico Co., Ltd Validation of Portable Monitoring Devices PMP-200GplusX (Pulse Watch) and "NEO" PMP-300E, v2 (Smart Watch) for Identification of Obstructive Sleep Apnea Contract (Kushida - PI) 6/17/10 - 6/16/12 ResMed Corporation Pediatric Nasal Mask Usability Study The purpose of this research is to conduct a usability study in the use of a pediatric nasal mask. Contract (Kushida – PI) 4/28/10 - 04/30/12 Merck A Phase III, Multi-Center, Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study to Evaluate the Safety and Efficacy of MK-4305 in Patients with Primary Insomnia-Study B. Contract (Kushida - PI) 10/1/09 - 9/30/10 Cephalon, Inc. A Randomized, Double-blind, Placebo-controlled, Functional Neuroimaging Study of the Effects of Armodafinil (200 mg/day) Treatment on Prefrontal Cortical Activation in Patients With Residual Excessive Sleepiness Associated With Obstructive Sleep Apnea/Hypopnea Syndrome Contract (Kushida - PI) 4/6/09 - 4/5/11 Ventus Medical, Inc. AERO: Advanced EPAP Research for OSAH, A Prospective, Multicenter Parallel Group, Sham-Controlled, Randomized, Double-Blinded Clinical Trial to Compare the Safety and Effectiveness of the Provent Professional Sleep Apnea Therapy Device to Sham for the Non-Invasive Treatment of Obstructive Sleep Apnea-Hypopnea Contract (Kushida - PI) 02/10/09 - 02/09/12 Merck A Phase IIb, Multi-Center, Randomized, Double-Blind, Placebo-Controlled, 2-Period Adaptive Crossover Polysomnography Study to Evaluate the Safety and Efficacy of MK-6096 in Patients with Primary Insomnia. Contract (Kushida - PI) 4/25/08 - 4/30/10 NCX MERCK Co. Inc. A Phase IIa, Randomized, Double-Blind, Placebo-Controlled, 3-Period Crossover, Adaptive Dose Design, Clinical Trial to Evaluate the Safety and Efficacy of MK-249 in Treating Refractory Excessive Daytime Sleepiness in Patients with Obstructive Sleep Apnea/Hypopnea Syndrome Appropriately Using Nasal Continuous Positive Airway Pressure (nCPAP) Therapy Department of Veterans Affairs (Kushida - PI) 10/1/06 - 9/30/11 NIDA/Stanford Biostatistical Consultation Contract (Kushida - PI) 8/1/06 - 12/31/10

Clete A. Kushida, M.D., Ph.D., RPSGT 50

Jazz Pharmaceuticals Xyrem (Sodium Oxybate) and Ambien (Zolpidem Tartrate) in the Treatment of Chronic Insomnia: A Randomized Double-Blind, Double-Dummy, Placebo-Controlled, Parallel Group Study NIH/NHLBI HL68060 (Kushida - PI) 10/1/02 - 7/31/10 NCX A.P.P.L.E.S. (Apnea Positive Pressure Long-Term Efficacy Study) The purpose of this multi-center study is to: assess the long-term efficacy of CPAP therapy; to identify specific neurocognitive deficits associated with OSA and which deficits are reversible; to develop a composite multivariate outcome measure to assess the clinical effectiveness of CPAP; and to compare cortical activation before and after CPAP therapy. Contract (Kushida - PI) 3/5/08 - 3/5/10 Respironics A-Flex Study: Positive Airway Pressure Initiation: Impact of Therapy Mode and Titration Process on Adherence and Outcomes. The purpose of this research is to determine if the comfort of A-Flex results in higher acceptance and adherence and better patient outcomes compared to alternative modes (CPAP and Auto CPAP) of positive airway pressure therapy. Contract (Kushida - PI) 6/4/08 - 10/28/09 Pacific Medico Validation of portable monitoring device PMP-300E for identification of obstructive sleep apnea Contract (Kushida - PI) 10/13/08 - 9/30/09 Cephalon, Inc. A Randomized, Double-Blind, Placebo-Controlled, Functional Neuroimaging Study of the Effects of Armodafinil (200mg/day) Treatment on Pre-Frontal Cortical Activation in Patients with Residual Excessive Sleepiness Associated with Obstructive Sleep Apnea/Hypopnea Syndrome

Contract (Kushida - PI) 7/31/08 - 7/30/09 GlaxoSmithKline Study RXP110908, A Polysomnography Study of GSK 1838262 (XP13512) Extended Release Tablets versus Placebo in the Treatment of Restless Legs Syndrome and Associated Sleep Disturbance Contract (Kushida - PI) 5/14/07 - 4/30/09 NCX Xenoport (XP083) A Randomized Double-Blind, Active- and Placebo-Controlled, Parallel Group Safety Study Assessing Simulated Driving Performance in XP13512 Treated Patients with Restless Legs Syndrome (XP083) Contract (Kushida - PI) 10/20/06 - 4/28/09 NCX Xenoport (XP055) An Open-Label, 52-week Extension Study Assessing XP13512 Safety and Efficacy in Patients with Restless Legs Syndrome Contract (Kushida - PI) 2/24/06 - 2/28/07 Xenoport (XP052) A Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of XP13512 in Patients with Restless Legs Syndrome Contract (Kushida - PI) 1/18/06 - 4/30/07 GlaxoSmithKline A 12-week, Randomized, Double-Blind, Parallel-group, Multicenter Study to Assess the Tolerability and Clinical Benefits of Ropinirole Extended Release (XR) Tablets Compared with Ropinirole Immediate Release (IR) Tablets in Subjects with Restless Legs Syndrome (RLS) Contract (Kushida – PI) 9/19/05 - 7/31/06 Schwarz Biosciences, Inc.

Clete A. Kushida, M.D., Ph.D., RPSGT 51

A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Five-Arm Parallel-Group Trial to Investigate the Efficacy and Safety of Four Different Transdermal Doses of Rotigotine in Subjects with Idiopathic Restless Legs Syndrome Contract (Kushida - PI) 7/22/05 - 9/30/06 Kyowa Pharmaceutical, Inc. A Phase II, Double-Blind, Placebo-Controlled, Randomized, Parallel-Group, Multicenter Study to Evaluate the Efficacy and Safety of 40mg/day KW-6002 (Istradefylline) in Subjects with Restless Legs Syndrome (RLS) Contract (Kushida - PI) 9/1/04 - 8/30/06 Hoana Medical, Inc. Sleep Disorders Data Comparison: The purpose of this study is to determine the viability of a mattress pad with built-in sensors which collects vital signs data. Contract (Kushida - PI) 5/1/04 - 4/11/05 Boehringer Ingleheim A Randomized, Double Blind, Placebo Controlled, Parallel Group Clinical Trial Comparing Fixed Doses of 0.25mg, 0.50 mg and 0.75 mg Pramipexole (Mirapex) Administered Orally to Investigate the Safety and Efficacy in Patients with Idiopathic Restless Legs Syndrome for 12 Weeks Contract (Kushida - PI) 3/28/03 - 3/27/05 Pharmacia (#001) A Phase II, Randomized, Double-Blind, Placebo Controlled, Dose Response Study of the Efficacy and Safety of Sumanirole in Patients with Idiopathic Restless Legs Syndrome: The purpose of this study is to assess the safety and efficacy of sumanirole in subjects with restless legs syndrome. Contract (Kushida - PI) 3/28/03 - 3/27/05 Pharmacia (#007) A Long-Term, Open Label, Flexible Dose Study of the Efficacy and Safety of Sumanirole in Patients with Idiopathic Restless Legs Syndrome: The purpose of this study is to assess the safety and efficacy of sumanirole in subjects with restless legs syndrome. NIH/NHLBI HL71515 (Mignot - PI; Kushida - Associate Investigator) 10/01/02 - 7/31/08 NCX Sleep Disordered Breathing, APOE and Lipid Metabolism The purpose of this project is to: study and extend our finding that APOE e4 increases the risk of sleep apnea in the general population using case/control and family designs; examine if polymorphisms in other genes regulating lipid levels are associated with sleep apnea; and study the relationship between lipid regulatory gene polymorphisms, lipid profile (LDL-cholesterol, HDL-cholesterol, triglycerides), plasma leptin (and other lipid regulatory hormones), and sleep apnea levels. Contract (Kushida - PI) 9/1/02 - 10/31/04 NCX Respironics (Rock-It) Evaluation of a Device that Provides Non-Invasive Nocturnal Electrical Stimulation of the Vestibular Nerve for the Initiation and Maintenance of Sleep: The purpose of this study is to gather information about the benefits of a new device, which delivers a small amount of electrical current through an earplug, specifically designed to focus the energy on the vestibular nerve. Contract (Kushida - PI) 2/21/02 - 12/31/02 GlaxoSmithKline A 12 Week, Double-Blind, Placebo-Controlled, Parallel Group Study to Assess the Efficacy of Ropinirole in Subjects with RLS Suffering from PLMS Contract (Kushida - PI) 5/23/01 - 6/30/01 Cephalon, Inc. The Effects of Modafinil (Provigil) on PLMD-Associated Daytime Sleepiness Contract (Guilleminault - PI; Kushida - Co-Investigator) 11/1/98 - 10/31/99

Clete A. Kushida, M.D., Ph.D., RPSGT 52

Mini-Mitter Co., Inc. Comparison Study of Actigraphic, Polysomnographic and Subjective Perception of Sleep Parameters NIH/NHLBI: R01-HL59659, (Carmelli - PI; Kushida - Consultant) 8/1/98 - 7/31/01 Sleep Apnea in Elderly Male Twins Contract (Dement - PI; Kushida - Co-Investigator) 8/14/97 - 11/30/01 LifeSleep Systems, Inc. Cervical Pillow for Reduction of Snoring and Sleep-Disordered Breathing