classification of infectious disease

Upload: saadtam

Post on 03-Jun-2018

261 views

Category:

Documents


0 download

TRANSCRIPT

  • 8/12/2019 Classification of Infectious Disease

    1/64

    Classification of the infection

    diseases

    Sorokhan V.D., MD, PhD

    Bukovinian State Medical UniversityDepartment of the infectious diseases and

    epidemiology

  • 8/12/2019 Classification of Infectious Disease

    2/64

    Microbiological Classification of Infectious

    Diseases

    Bacterial Gram-negativeGram-positive

    Viral DNA virus

    RNA virusEnveloped vs non-enveloped

    Fungal Disseminated

    Localized

    Parasitic Protozoa

    Helminths

    Prion

  • 8/12/2019 Classification of Infectious Disease

    3/64

    Gram-negative bacteria

    Gram-negativebacteria are

    those that are

    stained red orpink by Gram

    staining

    Gram-negative Pseudomonasaeruginosabacteria (pink-red rods)

    http://en.wikipedia.org/wiki/Gram_staininghttp://en.wikipedia.org/wiki/Gram_staininghttp://en.wikipedia.org/wiki/Pseudomonas_aeruginosahttp://en.wikipedia.org/wiki/Pseudomonas_aeruginosahttp://en.wikipedia.org/wiki/Pseudomonas_aeruginosahttp://en.wikipedia.org/wiki/Pseudomonas_aeruginosahttp://upload.wikimedia.org/wikipedia/commons/2/2d/Pseudomonas_aeruginosa_Gram.jpghttp://en.wikipedia.org/wiki/Gram_staininghttp://en.wikipedia.org/wiki/Gram_staining
  • 8/12/2019 Classification of Infectious Disease

    4/64

    Gram negative

    CocobacilliH. Influenzae, B. Pertussis

    Brucella spp., F. TularensisP. Multosida, L. pneumophila

    CocciNeisseria spp.

    Bacilli

    N. MeningitidisGlucose andmaltose +

    N. GonnorrhoeaeGlucose +

    Lactose + Lactose -

    Slow fermenterCitrobacterSerratia

    Fast fermenter

    KlebsiellaE.Coli

    Enterobacter

    Oxidase +V.CholeraeP. aeruginosa

    Strict anaerodeB. fragilis

    Oxidase -

    Urease Y. Pestis

    S. DysenteriaeSalmonnela spp.

    Urease +P. MirabilisH. pylori

  • 8/12/2019 Classification of Infectious Disease

    5/64

    Gram-positive bacteria

    Gram-positive bacteriaare those that arestained dark blue or

    violet by Gram staining.This is in contrast to

    Gram-negativebacteria, which cannotretain the crystal violetstain, instead taking up

    the counterstain

    (safraninor fuchsine)and appearing red orpink.

    Gram-positive Bacillusanthracisbacteria (purplerods) in cerebrospinal fluidsample. The other cells are

    white blood cells.

    http://en.wikipedia.org/wiki/Bacteriahttp://en.wikipedia.org/wiki/Gram_staininghttp://en.wikipedia.org/wiki/Gram-negative_bacteriahttp://en.wikipedia.org/wiki/Gram-negative_bacteriahttp://en.wikipedia.org/wiki/Counterstainhttp://en.wikipedia.org/wiki/Safraninhttp://en.wikipedia.org/wiki/Fuchsinehttp://en.wikipedia.org/wiki/Bacillus_anthracishttp://en.wikipedia.org/wiki/Bacillus_anthracishttp://en.wikipedia.org/wiki/Cerebrospinal_fluidhttp://en.wikipedia.org/wiki/White_blood_cellhttp://en.wikipedia.org/wiki/White_blood_cellhttp://en.wikipedia.org/wiki/Cerebrospinal_fluidhttp://en.wikipedia.org/wiki/Bacillus_anthracishttp://en.wikipedia.org/wiki/Bacillus_anthracishttp://en.wikipedia.org/wiki/File:Gram_Stain_Anthrax.jpghttp://en.wikipedia.org/wiki/Fuchsinehttp://en.wikipedia.org/wiki/Safraninhttp://en.wikipedia.org/wiki/Counterstainhttp://en.wikipedia.org/wiki/Gram-negative_bacteriahttp://en.wikipedia.org/wiki/Gram-negative_bacteriahttp://en.wikipedia.org/wiki/Gram-negative_bacteriahttp://en.wikipedia.org/wiki/Gram-negative_bacteriahttp://en.wikipedia.org/wiki/Gram_staininghttp://en.wikipedia.org/wiki/Bacteria
  • 8/12/2019 Classification of Infectious Disease

    6/64

    Gram positive

    cocciBacilli, Corinebacterium

    Clostridium, Listeria, Bacillus

    Staphylococcuscatalase +

    Streptococcuscatalase -

    S. AureusCoagulase + Coagulase -

    -hemolytic

    -hemolyticS. Pneumoniae

    S. ViridansS. Mutans

    -hemolyticE. Faecalis

    E. Faecium

    S. EpidermisNovobiocinsensitive

    S. SaprophyticusNovobiocinresistant

    Group A

    S. Piogenes

    Group B

    S.agalactiae

  • 8/12/2019 Classification of Infectious Disease

    7/64

    Genus Importantspecies

    Gramstaining

    Shape Capsulation Motility Respiration

    Bordetella Bordetellapertussis Gram-negative Smallcoccobacilli Encapsulated aerobic

    Borrelia Borreliaburgdorferi

    Gram-negative, butstains poorly

    highly motile

    Brucella Brucella abortus

    Brucella canisBrucellamelitensisBrucella suis

    Gram-

    negative

    Small

    coccobacilli

    Unencapsulated Aerobic

    Campylobacter Campylobacterjejuni

    Gram-negative

    Curved, spiral,or S-shapedwith single,polar

    flagellum

    characteristicdartingmotion

    microaerophilic

    Basic laboratory characteristics

    http://en.wikipedia.org/wiki/Gram_staininghttp://en.wikipedia.org/wiki/Gram_staininghttp://en.wikipedia.org/wiki/Bordetellahttp://en.wikipedia.org/wiki/Bordetella_pertussishttp://en.wikipedia.org/wiki/Bordetella_pertussishttp://en.wikipedia.org/wiki/Coccobacillihttp://en.wikipedia.org/wiki/Borreliahttp://en.wikipedia.org/wiki/Borrelia_burgdorferihttp://en.wikipedia.org/wiki/Borrelia_burgdorferihttp://en.wikipedia.org/wiki/Brucellahttp://en.wikipedia.org/wiki/Brucella_abortushttp://en.wikipedia.org/wiki/Brucella_canishttp://en.wikipedia.org/wiki/Brucella_melitensishttp://en.wikipedia.org/wiki/Brucella_melitensishttp://en.wikipedia.org/wiki/Brucella_suishttp://en.wikipedia.org/wiki/Coccobacillihttp://en.wikipedia.org/wiki/Campylobacterhttp://en.wikipedia.org/wiki/Campylobacter_jejunihttp://en.wikipedia.org/wiki/Campylobacter_jejunihttp://en.wikipedia.org/wiki/Microaerophilichttp://en.wikipedia.org/wiki/Microaerophilichttp://en.wikipedia.org/wiki/Campylobacter_jejunihttp://en.wikipedia.org/wiki/Campylobacter_jejunihttp://en.wikipedia.org/wiki/Campylobacterhttp://en.wikipedia.org/wiki/Coccobacillihttp://en.wikipedia.org/wiki/Brucella_suishttp://en.wikipedia.org/wiki/Brucella_melitensishttp://en.wikipedia.org/wiki/Brucella_melitensishttp://en.wikipedia.org/wiki/Brucella_canishttp://en.wikipedia.org/wiki/Brucella_abortushttp://en.wikipedia.org/wiki/Brucellahttp://en.wikipedia.org/wiki/Borrelia_burgdorferihttp://en.wikipedia.org/wiki/Borrelia_burgdorferihttp://en.wikipedia.org/wiki/Borreliahttp://en.wikipedia.org/wiki/Coccobacillihttp://en.wikipedia.org/wiki/Bordetella_pertussishttp://en.wikipedia.org/wiki/Bordetella_pertussishttp://en.wikipedia.org/wiki/Bordetellahttp://en.wikipedia.org/wiki/Gram_staininghttp://en.wikipedia.org/wiki/Gram_staining
  • 8/12/2019 Classification of Infectious Disease

    8/64

    Genus Importantspecies

    Gramstaining

    Shape Capsulation Motility Respiration

    ChlamydiaandChlamydophila ChlamydiapneumoniaeChlamydiatrachomatisChlamydophilapsittaci

    (not Gram-stained) Small, round,ovoid motile Facultative orstrictly aerobic

    Clostridium ClostridiumbotulinumClostridiumdifficileClostridiumperfringensClostridiumtetani

    Gram-positive

    Large, blunt-ended rods

    mostlymotile

    Obligateanaerobic

    Corynebacterium Corynebacteriumdiphtheriae

    Gram-positive(unevenly)

    Small,slender,pleomorphic

    rods

    unencapsulated nonmotile Mostlyfacultativeanaerobic

    Enterococcus EnterococcusfaecalisEnterococcusfaecium

    Gram-positive

    Round toovoid

    FacultativeAnaerobic

    http://en.wikipedia.org/wiki/Gram_staininghttp://en.wikipedia.org/wiki/Gram_staininghttp://en.wikipedia.org/wiki/Chlamydia_(bacterium)http://en.wikipedia.org/wiki/Chlamydophilahttp://en.wikipedia.org/wiki/Chlamydia_pneumoniaehttp://en.wikipedia.org/wiki/Chlamydia_pneumoniaehttp://en.wikipedia.org/wiki/Chlamydia_trachomatishttp://en.wikipedia.org/wiki/Chlamydia_trachomatishttp://en.wikipedia.org/wiki/Chlamydophila_psittacihttp://en.wikipedia.org/wiki/Chlamydophila_psittacihttp://en.wikipedia.org/wiki/Clostridiumhttp://en.wikipedia.org/wiki/Clostridium_botulinumhttp://en.wikipedia.org/wiki/Clostridium_botulinumhttp://en.wikipedia.org/wiki/Clostridium_difficilehttp://en.wikipedia.org/wiki/Clostridium_difficilehttp://en.wikipedia.org/wiki/Clostridium_perfringenshttp://en.wikipedia.org/wiki/Clostridium_perfringenshttp://en.wikipedia.org/wiki/Clostridium_tetanihttp://en.wikipedia.org/wiki/Clostridium_tetanihttp://en.wikipedia.org/wiki/Corynebacteriumhttp://en.wikipedia.org/wiki/Corynebacterium_diphtheriaehttp://en.wikipedia.org/wiki/Corynebacterium_diphtheriaehttp://en.wikipedia.org/wiki/Pleomorphichttp://en.wikipedia.org/wiki/Enterococcushttp://en.wikipedia.org/wiki/Enterococcus_faecalishttp://en.wikipedia.org/wiki/Enterococcus_faecalishttp://en.wikipedia.org/wiki/Enterococcus_faeciumhttp://en.wikipedia.org/wiki/Enterococcus_faeciumhttp://en.wikipedia.org/wiki/Enterococcus_faeciumhttp://en.wikipedia.org/wiki/Enterococcus_faeciumhttp://en.wikipedia.org/wiki/Enterococcus_faecalishttp://en.wikipedia.org/wiki/Enterococcus_faecalishttp://en.wikipedia.org/wiki/Enterococcushttp://en.wikipedia.org/wiki/Pleomorphichttp://en.wikipedia.org/wiki/Corynebacterium_diphtheriaehttp://en.wikipedia.org/wiki/Corynebacterium_diphtheriaehttp://en.wikipedia.org/wiki/Corynebacteriumhttp://en.wikipedia.org/wiki/Clostridium_tetanihttp://en.wikipedia.org/wiki/Clostridium_tetanihttp://en.wikipedia.org/wiki/Clostridium_perfringenshttp://en.wikipedia.org/wiki/Clostridium_perfringenshttp://en.wikipedia.org/wiki/Clostridium_difficilehttp://en.wikipedia.org/wiki/Clostridium_difficilehttp://en.wikipedia.org/wiki/Clostridium_botulinumhttp://en.wikipedia.org/wiki/Clostridium_botulinumhttp://en.wikipedia.org/wiki/Clostridiumhttp://en.wikipedia.org/wiki/Chlamydophila_psittacihttp://en.wikipedia.org/wiki/Chlamydophila_psittacihttp://en.wikipedia.org/wiki/Chlamydia_trachomatishttp://en.wikipedia.org/wiki/Chlamydia_trachomatishttp://en.wikipedia.org/wiki/Chlamydia_pneumoniaehttp://en.wikipedia.org/wiki/Chlamydia_pneumoniaehttp://en.wikipedia.org/wiki/Chlamydophilahttp://en.wikipedia.org/wiki/Chlamydia_(bacterium)http://en.wikipedia.org/wiki/Gram_staininghttp://en.wikipedia.org/wiki/Gram_staining
  • 8/12/2019 Classification of Infectious Disease

    9/64

  • 8/12/2019 Classification of Infectious Disease

    10/64

    Genus Importantspecies

    Gramstaining

    Shape Capsulation Motility Respiration

    Legionella Legionellapneumophila

    Gram-negative, butstains poorly

    Slender rod innature,cocobacillary

    in laboratory.monotrichiousflagella

    unencapsulated motile

    Leptospira Leptospirainterrogans

    Gram-negative, butstains poorly

    Long, veryslender,flexible,spiral- orcorkscrew-

    shaped rods

    highly motile

    Listeria Listeriamonocytogenes

    Gram-positive,darkly

    Slender, shortrods

    Distincttumblingmotility inliquidmedium

    Mycobacterium Mycobacteriumleprae

    MycobacteriumtuberculosisMycobacteriumulcerans

    (none) Long, slenderrods

    nonmotile aerobic

    http://en.wikipedia.org/wiki/Gram_staininghttp://en.wikipedia.org/wiki/Gram_staininghttp://en.wikipedia.org/wiki/Legionellahttp://en.wikipedia.org/wiki/Legionella_pneumophilahttp://en.wikipedia.org/wiki/Legionella_pneumophilahttp://en.wikipedia.org/wiki/Leptospirahttp://en.wikipedia.org/wiki/Leptospira_interroganshttp://en.wikipedia.org/wiki/Leptospira_interroganshttp://en.wikipedia.org/wiki/Listeriahttp://en.wikipedia.org/wiki/Listeria_monocytogeneshttp://en.wikipedia.org/wiki/Listeria_monocytogeneshttp://en.wikipedia.org/wiki/Mycobacteriumhttp://en.wikipedia.org/wiki/Mycobacterium_lepraehttp://en.wikipedia.org/wiki/Mycobacterium_lepraehttp://en.wikipedia.org/wiki/Mycobacterium_tuberculosishttp://en.wikipedia.org/wiki/Mycobacterium_tuberculosishttp://en.wikipedia.org/wiki/Mycobacterium_ulceranshttp://en.wikipedia.org/wiki/Mycobacterium_ulceranshttp://en.wikipedia.org/wiki/Mycobacterium_ulceranshttp://en.wikipedia.org/wiki/Mycobacterium_ulceranshttp://en.wikipedia.org/wiki/Mycobacterium_tuberculosishttp://en.wikipedia.org/wiki/Mycobacterium_tuberculosishttp://en.wikipedia.org/wiki/Mycobacterium_lepraehttp://en.wikipedia.org/wiki/Mycobacterium_lepraehttp://en.wikipedia.org/wiki/Mycobacteriumhttp://en.wikipedia.org/wiki/Listeria_monocytogeneshttp://en.wikipedia.org/wiki/Listeria_monocytogeneshttp://en.wikipedia.org/wiki/Listeriahttp://en.wikipedia.org/wiki/Leptospira_interroganshttp://en.wikipedia.org/wiki/Leptospira_interroganshttp://en.wikipedia.org/wiki/Leptospirahttp://en.wikipedia.org/wiki/Legionella_pneumophilahttp://en.wikipedia.org/wiki/Legionella_pneumophilahttp://en.wikipedia.org/wiki/Legionellahttp://en.wikipedia.org/wiki/Gram_staininghttp://en.wikipedia.org/wiki/Gram_staining
  • 8/12/2019 Classification of Infectious Disease

    11/64

    Genus Importantspecies

    Gramstaining

    Shape Capsulation Motility Respiration

    Mycoplasma Mycoplasmapneumoniae

    (none) Plastic,pleomorphic

    Neisseria NeisseriagonorrhoeaeNeisseriameningitidis

    Gram-negative

    Kidney bean-shaped

    aerobic

    Pseudomonas Pseudomonasaeruginosa

    Gram-negative

    rods encapsulated motile Obligate aerobic

    Rickettsia Rickettsiarickettsii

    Gram-negative, butstains poorly

    Small, rod-likecoccobacillary

    http://en.wikipedia.org/wiki/Gram_staininghttp://en.wikipedia.org/wiki/Gram_staininghttp://en.wikipedia.org/wiki/Mycoplasmahttp://en.wikipedia.org/wiki/Mycoplasma_pneumoniaehttp://en.wikipedia.org/wiki/Mycoplasma_pneumoniaehttp://en.wikipedia.org/wiki/Neisseriahttp://en.wikipedia.org/wiki/Neisseria_gonorrhoeaehttp://en.wikipedia.org/wiki/Neisseria_gonorrhoeaehttp://en.wikipedia.org/wiki/Neisseria_meningitidishttp://en.wikipedia.org/wiki/Neisseria_meningitidishttp://en.wikipedia.org/wiki/Pseudomonashttp://en.wikipedia.org/wiki/Pseudomonas_aeruginosahttp://en.wikipedia.org/wiki/Pseudomonas_aeruginosahttp://en.wikipedia.org/wiki/Rickettsiahttp://en.wikipedia.org/wiki/Rickettsia_rickettsiihttp://en.wikipedia.org/wiki/Rickettsia_rickettsiihttp://en.wikipedia.org/wiki/Rickettsia_rickettsiihttp://en.wikipedia.org/wiki/Rickettsia_rickettsiihttp://en.wikipedia.org/wiki/Rickettsiahttp://en.wikipedia.org/wiki/Pseudomonas_aeruginosahttp://en.wikipedia.org/wiki/Pseudomonas_aeruginosahttp://en.wikipedia.org/wiki/Pseudomonashttp://en.wikipedia.org/wiki/Neisseria_meningitidishttp://en.wikipedia.org/wiki/Neisseria_meningitidishttp://en.wikipedia.org/wiki/Neisseria_gonorrhoeaehttp://en.wikipedia.org/wiki/Neisseria_gonorrhoeaehttp://en.wikipedia.org/wiki/Neisseriahttp://en.wikipedia.org/wiki/Mycoplasma_pneumoniaehttp://en.wikipedia.org/wiki/Mycoplasma_pneumoniaehttp://en.wikipedia.org/wiki/Mycoplasmahttp://en.wikipedia.org/wiki/Gram_staininghttp://en.wikipedia.org/wiki/Gram_staining
  • 8/12/2019 Classification of Infectious Disease

    12/64

    Genus Importantspecies

    Gramstaining

    Shape Capsulation Motility Respiration

    Salmonella Salmonella typhiSalmonellatyphimurium

    Gram-negative

    Facultativeanaerobic

    Shigella Shigella sonnei Gram-negative

    rods Facultativeanaerobic

    Staphylococcus StaphylococcusaureusStaphylococcusepidermidisStaphylococcussaprophyticus

    Gram-positive,darkly

    Round cocci Facultativeanaerobic

    Streptococcus StreptococcusagalactiaeStreptococcuspneumoniaeStreptococcuspyogenes

    Gram-positive

    ovoid tospherical

    nonmotile Facultativeanaerobic

    http://en.wikipedia.org/wiki/Gram_staininghttp://en.wikipedia.org/wiki/Gram_staininghttp://en.wikipedia.org/wiki/Salmonellahttp://en.wikipedia.org/wiki/Salmonella_typhihttp://en.wikipedia.org/wiki/Salmonella_typhimuriumhttp://en.wikipedia.org/wiki/Salmonella_typhimuriumhttp://en.wikipedia.org/wiki/Shigellahttp://en.wikipedia.org/wiki/Shigella_sonneihttp://en.wikipedia.org/wiki/Staphylococcushttp://en.wikipedia.org/wiki/Staphylococcus_aureushttp://en.wikipedia.org/wiki/Staphylococcus_aureushttp://en.wikipedia.org/wiki/Staphylococcus_epidermidishttp://en.wikipedia.org/wiki/Staphylococcus_epidermidishttp://en.wikipedia.org/wiki/Staphylococcus_saprophyticushttp://en.wikipedia.org/wiki/Staphylococcus_saprophyticushttp://en.wikipedia.org/wiki/Streptococcushttp://en.wikipedia.org/wiki/Streptococcus_agalactiaehttp://en.wikipedia.org/wiki/Streptococcus_agalactiaehttp://en.wikipedia.org/wiki/Streptococcus_pneumoniaehttp://en.wikipedia.org/wiki/Streptococcus_pneumoniaehttp://en.wikipedia.org/wiki/Streptococcus_pyogeneshttp://en.wikipedia.org/wiki/Streptococcus_pyogeneshttp://en.wikipedia.org/wiki/Streptococcus_pyogeneshttp://en.wikipedia.org/wiki/Streptococcus_pyogeneshttp://en.wikipedia.org/wiki/Streptococcus_pneumoniaehttp://en.wikipedia.org/wiki/Streptococcus_pneumoniaehttp://en.wikipedia.org/wiki/Streptococcus_agalactiaehttp://en.wikipedia.org/wiki/Streptococcus_agalactiaehttp://en.wikipedia.org/wiki/Streptococcushttp://en.wikipedia.org/wiki/Staphylococcus_saprophyticushttp://en.wikipedia.org/wiki/Staphylococcus_saprophyticushttp://en.wikipedia.org/wiki/Staphylococcus_epidermidishttp://en.wikipedia.org/wiki/Staphylococcus_epidermidishttp://en.wikipedia.org/wiki/Staphylococcus_aureushttp://en.wikipedia.org/wiki/Staphylococcus_aureushttp://en.wikipedia.org/wiki/Staphylococcushttp://en.wikipedia.org/wiki/Shigella_sonneihttp://en.wikipedia.org/wiki/Shigellahttp://en.wikipedia.org/wiki/Salmonella_typhimuriumhttp://en.wikipedia.org/wiki/Salmonella_typhimuriumhttp://en.wikipedia.org/wiki/Salmonella_typhihttp://en.wikipedia.org/wiki/Salmonellahttp://en.wikipedia.org/wiki/Gram_staininghttp://en.wikipedia.org/wiki/Gram_staining
  • 8/12/2019 Classification of Infectious Disease

    13/64

    Genus Importantspecies

    Gramstaining

    Shape Capsulation Motility Respiration

    Treponema Treponemapallidum

    Gram-negative,but stainspoorly

    Long,slender,flexible,spiral- orcorkscrew-shaped rods

    highlymotile

    Vibrio Vibriocholerae

    Gram-negative

    Short,curved, rod-shaped withsingle polar

    flagellum

    rapidlymotile

    Facultativeanaerobic

    Yersinia Yersiniapestis

    Gram-negative,stainsbipolarly

    Small rods encapsulated nonmotile FacultativeAnaerobe

    http://en.wikipedia.org/wiki/Gram_staininghttp://en.wikipedia.org/wiki/Gram_staininghttp://en.wikipedia.org/wiki/Treponemahttp://en.wikipedia.org/wiki/Treponema_pallidumhttp://en.wikipedia.org/wiki/Treponema_pallidumhttp://en.wikipedia.org/wiki/Vibriohttp://en.wikipedia.org/wiki/Vibrio_choleraehttp://en.wikipedia.org/wiki/Vibrio_choleraehttp://en.wikipedia.org/wiki/Yersiniahttp://en.wikipedia.org/wiki/Yersinia_pestishttp://en.wikipedia.org/wiki/Yersinia_pestishttp://en.wikipedia.org/wiki/Yersinia_pestishttp://en.wikipedia.org/wiki/Yersinia_pestishttp://en.wikipedia.org/wiki/Yersiniahttp://en.wikipedia.org/wiki/Vibrio_choleraehttp://en.wikipedia.org/wiki/Vibrio_choleraehttp://en.wikipedia.org/wiki/Vibriohttp://en.wikipedia.org/wiki/Treponema_pallidumhttp://en.wikipedia.org/wiki/Treponema_pallidumhttp://en.wikipedia.org/wiki/Treponemahttp://en.wikipedia.org/wiki/Gram_staininghttp://en.wikipedia.org/wiki/Gram_staining
  • 8/12/2019 Classification of Infectious Disease

    14/64

  • 8/12/2019 Classification of Infectious Disease

    15/64

    Species of human pathogenic bacteria

    Species Transmission Diseases Treatment Prevention laboratorydiagnosis

    Bordetellapertussis

    Contact withrespiratorydroplets expelledby infectedhuman hosts.

    Whooping cough

    Complications:

    Secondarybacterialpneumonia

    Macrolideantibiotics

    Azithromycin

    Erythromycin

    Clarithromycin

    Pertussisvaccine, DPTvaccine

    Directimmunofluorescence

    PCR amplification

    Borreliaburgdorferi

    Ixodesticksreservoir in deer,mice and otherrodents

    Lyme disease Early stages:cephalosporinsamoxicillindoxycycline

    If arthriticsymptoms haveappeared:

    Longer courses

    of antibiotics

    Lyme vaccine

    wearingclothing thatlimits skinexposure toticks

    insectrepellent

    Microscopy usingGiemsaor Wrightstain

    PCR

    serology(lowprecision rate)

    http://en.wikipedia.org/wiki/Transmission_(medicine)http://en.wikipedia.org/wiki/Laboratory_diagnosis_of_bacteriahttp://en.wikipedia.org/wiki/Laboratory_diagnosis_of_bacteriahttp://en.wikipedia.org/wiki/Bordetella_pertussishttp://en.wikipedia.org/wiki/Bordetella_pertussishttp://en.wikipedia.org/wiki/Whooping_coughhttp://en.wikipedia.org/wiki/Bacterial_pneumoniahttp://en.wikipedia.org/wiki/Bacterial_pneumoniahttp://en.wikipedia.org/wiki/Macrolidehttp://en.wikipedia.org/wiki/Antibioticshttp://en.wikipedia.org/wiki/Azithromycinhttp://en.wikipedia.org/wiki/Erythromycinhttp://en.wikipedia.org/wiki/Clarithromycinhttp://en.wikipedia.org/wiki/DPT_vaccinehttp://en.wikipedia.org/wiki/DPT_vaccinehttp://en.wikipedia.org/wiki/Immunofluorescencehttp://en.wikipedia.org/wiki/PCR_amplificationhttp://en.wikipedia.org/wiki/Borrelia_burgdorferihttp://en.wikipedia.org/wiki/Borrelia_burgdorferihttp://en.wikipedia.org/wiki/Ixodeshttp://en.wikipedia.org/wiki/Lyme_diseasehttp://en.wikipedia.org/wiki/Cephalosporinshttp://en.wikipedia.org/wiki/Amoxicillinhttp://en.wikipedia.org/wiki/Doxycyclinehttp://en.wikipedia.org/wiki/Lyme_vaccinehttp://en.wikipedia.org/wiki/Insect_repellenthttp://en.wikipedia.org/wiki/Insect_repellenthttp://en.wikipedia.org/wiki/Giemsa_stainhttp://en.wikipedia.org/wiki/Wright_stainhttp://en.wikipedia.org/wiki/Wright_stainhttp://en.wikipedia.org/wiki/Polymerase_chain_reactionhttp://en.wikipedia.org/wiki/Serologyhttp://en.wikipedia.org/wiki/Precision_ratehttp://en.wikipedia.org/wiki/Precision_ratehttp://en.wikipedia.org/wiki/Serologyhttp://en.wikipedia.org/wiki/Polymerase_chain_reactionhttp://en.wikipedia.org/wiki/Wright_stainhttp://en.wikipedia.org/wiki/Wright_stainhttp://en.wikipedia.org/wiki/Giemsa_stainhttp://en.wikipedia.org/wiki/Insect_repellenthttp://en.wikipedia.org/wiki/Insect_repellenthttp://en.wikipedia.org/wiki/Lyme_vaccinehttp://en.wikipedia.org/wiki/Doxycyclinehttp://en.wikipedia.org/wiki/Amoxicillinhttp://en.wikipedia.org/wiki/Cephalosporinshttp://en.wikipedia.org/wiki/Lyme_diseasehttp://en.wikipedia.org/wiki/Ixodeshttp://en.wikipedia.org/wiki/Borrelia_burgdorferihttp://en.wikipedia.org/wiki/Borrelia_burgdorferihttp://en.wikipedia.org/wiki/PCR_amplificationhttp://en.wikipedia.org/wiki/Immunofluorescencehttp://en.wikipedia.org/wiki/DPT_vaccinehttp://en.wikipedia.org/wiki/DPT_vaccinehttp://en.wikipedia.org/wiki/Clarithromycinhttp://en.wikipedia.org/wiki/Erythromycinhttp://en.wikipedia.org/wiki/Azithromycinhttp://en.wikipedia.org/wiki/Antibioticshttp://en.wikipedia.org/wiki/Macrolidehttp://en.wikipedia.org/wiki/Bacterial_pneumoniahttp://en.wikipedia.org/wiki/Bacterial_pneumoniahttp://en.wikipedia.org/wiki/Whooping_coughhttp://en.wikipedia.org/wiki/Bordetella_pertussishttp://en.wikipedia.org/wiki/Bordetella_pertussishttp://en.wikipedia.org/wiki/Laboratory_diagnosis_of_bacteriahttp://en.wikipedia.org/wiki/Laboratory_diagnosis_of_bacteriahttp://en.wikipedia.org/wiki/Transmission_(medicine)
  • 8/12/2019 Classification of Infectious Disease

    16/64

  • 8/12/2019 Classification of Infectious Disease

    17/64

    Species of human pathogenic bacteria

    Species Transmission Diseases Treatment Prevention laboratorydiagnosis

    Chlamydiapneumoniae

    Respiratorydroplets

    Community-acquiredrespiratoryinfection

    Doxycycline

    Erythromycin

    None None for routine use

    Chlamydiatrachomatis

    Sexual (NGU,LGV)

    Direct orcontaminatedsurfaces and flies(trachoma)

    Passage throughbirth canal (ICN)

    Nongonococcalurethritis(NGU)

    Lymphogranuloma venereum(LGV)

    Trachoma

    Inclusionconjunctivitis of

    the newborn(ICN)

    Azithromycin

    Erythromycin

    Tetracyclines

    Doxycycline

    No vaccine

    Erythromycinor silvernitrate innewborn'seyes

    Safe sex

    Cellular cytoplasmicinclusions byimmunofluorescence

    DNA hybridization

    ELISAforlipopolysaccharides

    http://en.wikipedia.org/wiki/Transmission_(medicine)http://en.wikipedia.org/wiki/Laboratory_diagnosis_of_bacteriahttp://en.wikipedia.org/wiki/Laboratory_diagnosis_of_bacteriahttp://en.wikipedia.org/wiki/Chlamydia_pneumoniaehttp://en.wikipedia.org/wiki/Chlamydia_pneumoniaehttp://en.wikipedia.org/wiki/Doxycyclinehttp://en.wikipedia.org/wiki/Erythromycinhttp://en.wikipedia.org/wiki/Chlamydia_trachomatishttp://en.wikipedia.org/wiki/Chlamydia_trachomatishttp://en.wikipedia.org/wiki/Lymphogranuloma_venereumhttp://en.wikipedia.org/wiki/Lymphogranuloma_venereumhttp://en.wikipedia.org/wiki/Inclusion_conjunctivitis_of_the_newbornhttp://en.wikipedia.org/wiki/Nongonococcal_urethritishttp://en.wikipedia.org/wiki/Nongonococcal_urethritishttp://en.wikipedia.org/wiki/Lymphogranuloma_venereumhttp://en.wikipedia.org/wiki/Lymphogranuloma_venereumhttp://en.wikipedia.org/wiki/Trachomahttp://en.wikipedia.org/wiki/Inclusion_conjunctivitis_of_the_newbornhttp://en.wikipedia.org/wiki/Inclusion_conjunctivitis_of_the_newbornhttp://en.wikipedia.org/wiki/Inclusion_conjunctivitis_of_the_newbornhttp://en.wikipedia.org/wiki/Azithromycinhttp://en.wikipedia.org/wiki/Erythromycinhttp://en.wikipedia.org/wiki/Tetracyclineshttp://en.wikipedia.org/wiki/Doxycyclinehttp://en.wikipedia.org/wiki/Safe_sexhttp://en.wikipedia.org/wiki/Immunofluorescencehttp://en.wikipedia.org/wiki/DNA_hybridizationhttp://en.wikipedia.org/wiki/ELISAhttp://en.wikipedia.org/wiki/ELISAhttp://en.wikipedia.org/wiki/DNA_hybridizationhttp://en.wikipedia.org/wiki/Immunofluorescencehttp://en.wikipedia.org/wiki/Safe_sexhttp://en.wikipedia.org/wiki/Doxycyclinehttp://en.wikipedia.org/wiki/Tetracyclineshttp://en.wikipedia.org/wiki/Erythromycinhttp://en.wikipedia.org/wiki/Azithromycinhttp://en.wikipedia.org/wiki/Inclusion_conjunctivitis_of_the_newbornhttp://en.wikipedia.org/wiki/Inclusion_conjunctivitis_of_the_newbornhttp://en.wikipedia.org/wiki/Inclusion_conjunctivitis_of_the_newbornhttp://en.wikipedia.org/wiki/Trachomahttp://en.wikipedia.org/wiki/Lymphogranuloma_venereumhttp://en.wikipedia.org/wiki/Lymphogranuloma_venereumhttp://en.wikipedia.org/wiki/Nongonococcal_urethritishttp://en.wikipedia.org/wiki/Nongonococcal_urethritishttp://en.wikipedia.org/wiki/Inclusion_conjunctivitis_of_the_newbornhttp://en.wikipedia.org/wiki/Lymphogranuloma_venereumhttp://en.wikipedia.org/wiki/Lymphogranuloma_venereumhttp://en.wikipedia.org/wiki/Chlamydia_trachomatishttp://en.wikipedia.org/wiki/Chlamydia_trachomatishttp://en.wikipedia.org/wiki/Erythromycinhttp://en.wikipedia.org/wiki/Doxycyclinehttp://en.wikipedia.org/wiki/Chlamydia_pneumoniaehttp://en.wikipedia.org/wiki/Chlamydia_pneumoniaehttp://en.wikipedia.org/wiki/Laboratory_diagnosis_of_bacteriahttp://en.wikipedia.org/wiki/Laboratory_diagnosis_of_bacteriahttp://en.wikipedia.org/wiki/Transmission_(medicine)
  • 8/12/2019 Classification of Infectious Disease

    18/64

    Species of human pathogenic bacteria

    Species Transmission Diseases Treatment Prevention laboratorydiagnosis

    Chlamydophilapsittaci

    Inhalation ofdust withsecretions orfeces from birds(e.g. parrots)

    Psittacosis Tetracycline

    Doxycycline

    Erythromycin(less efficient)

    Rise in antibody titreComplement fixation

    indirectimmunofluorescence

    Clostridiumbotulinum

    Spores from soiland aquaticsedimentscontaminatingvegetables, meatand fish

    Botulism Antitoxin(horseantiserum)

    Proper foodpreservationtechniques

    Mouse inoculationdetects toxin fromfood, intestinalcontents or serum

    Culture in standardaerobic culture

    http://en.wikipedia.org/wiki/Transmission_(medicine)http://en.wikipedia.org/wiki/Laboratory_diagnosis_of_bacteriahttp://en.wikipedia.org/wiki/Laboratory_diagnosis_of_bacteriahttp://en.wikipedia.org/wiki/Chlamydophila_psittacihttp://en.wikipedia.org/wiki/Chlamydophila_psittacihttp://en.wikipedia.org/wiki/Psittacosishttp://en.wikipedia.org/wiki/Tetracyclinehttp://en.wikipedia.org/wiki/Doxycyclinehttp://en.wikipedia.org/wiki/Erythromycinhttp://en.wikipedia.org/wiki/Clostridium_botulinumhttp://en.wikipedia.org/wiki/Clostridium_botulinumhttp://en.wikipedia.org/wiki/Botulismhttp://en.wikipedia.org/wiki/Antitoxinhttp://en.wikipedia.org/wiki/Antiserumhttp://en.wikipedia.org/wiki/Antiserumhttp://en.wikipedia.org/wiki/Antitoxinhttp://en.wikipedia.org/wiki/Botulismhttp://en.wikipedia.org/wiki/Clostridium_botulinumhttp://en.wikipedia.org/wiki/Clostridium_botulinumhttp://en.wikipedia.org/wiki/Erythromycinhttp://en.wikipedia.org/wiki/Doxycyclinehttp://en.wikipedia.org/wiki/Tetracyclinehttp://en.wikipedia.org/wiki/Psittacosishttp://en.wikipedia.org/wiki/Chlamydophila_psittacihttp://en.wikipedia.org/wiki/Chlamydophila_psittacihttp://en.wikipedia.org/wiki/Laboratory_diagnosis_of_bacteriahttp://en.wikipedia.org/wiki/Laboratory_diagnosis_of_bacteriahttp://en.wikipedia.org/wiki/Transmission_(medicine)
  • 8/12/2019 Classification of Infectious Disease

    19/64

    Species of human pathogenic bacteria

    Species Transmission Diseases Treatment Prevention laboratorydiagnosis

    Clostridiumdifficile

    Spores bothindoors andoutdoors

    Human flora,overgrowingwhen other florais depleted

    Pseudomembranous colitis

    Discontinuingpredisposingantibiotic

    Fluid andelectrolytereplacement

    Vancomycinormetronidazoleifsevere

    None ELISAfor ToxinELISAfor toxin A orB

    Endoscopyforpseudomembrane

    Clostridiumperfringens

    Spores in soil

    Human florainvagina and GItract

    Gas gangrene

    Acute foodpoisoning

    Anaerobiccellulitis

    Food poisoning:

    Self-limiting;Supportive careis sufficient

    Appropriatefood handling

    Microscopically

    Blood agar culture,forming double-zone-hemolysis

    Sugar fermentation

    Organic acid

    production

    http://en.wikipedia.org/wiki/Transmission_(medicine)http://en.wikipedia.org/wiki/Laboratory_diagnosis_of_bacteriahttp://en.wikipedia.org/wiki/Laboratory_diagnosis_of_bacteriahttp://en.wikipedia.org/wiki/Clostridium_difficilehttp://en.wikipedia.org/wiki/Clostridium_difficilehttp://en.wikipedia.org/wiki/Human_florahttp://en.wikipedia.org/wiki/Pseudomembranous_colitishttp://en.wikipedia.org/wiki/Pseudomembranous_colitishttp://en.wikipedia.org/wiki/Vancomycinhttp://en.wikipedia.org/wiki/Metronidazolehttp://en.wikipedia.org/wiki/ELISAhttp://en.wikipedia.org/wiki/Clostridium_difficilehttp://en.wikipedia.org/wiki/Clostridium_difficilehttp://en.wikipedia.org/wiki/Endoscopyhttp://en.wikipedia.org/wiki/Clostridium_perfringenshttp://en.wikipedia.org/wiki/Clostridium_perfringenshttp://en.wikipedia.org/wiki/Human_florahttp://en.wikipedia.org/wiki/Gas_gangrenehttp://en.wikipedia.org/wiki/Food_poisoninghttp://en.wikipedia.org/wiki/Food_poisoninghttp://en.wikipedia.org/wiki/Anaerobic_cellulitishttp://en.wikipedia.org/wiki/Anaerobic_cellulitishttp://en.wikipedia.org/wiki/Beta_hemolysishttp://en.wikipedia.org/wiki/Beta_hemolysishttp://en.wikipedia.org/wiki/Beta_hemolysishttp://en.wikipedia.org/wiki/Beta_hemolysishttp://en.wikipedia.org/wiki/Beta_hemolysishttp://en.wikipedia.org/wiki/Anaerobic_cellulitishttp://en.wikipedia.org/wiki/Anaerobic_cellulitishttp://en.wikipedia.org/wiki/Food_poisoninghttp://en.wikipedia.org/wiki/Food_poisoninghttp://en.wikipedia.org/wiki/Gas_gangrenehttp://en.wikipedia.org/wiki/Human_florahttp://en.wikipedia.org/wiki/Clostridium_perfringenshttp://en.wikipedia.org/wiki/Clostridium_perfringenshttp://en.wikipedia.org/wiki/Endoscopyhttp://en.wikipedia.org/wiki/Clostridium_difficilehttp://en.wikipedia.org/wiki/Clostridium_difficilehttp://en.wikipedia.org/wiki/ELISAhttp://en.wikipedia.org/wiki/Metronidazolehttp://en.wikipedia.org/wiki/Vancomycinhttp://en.wikipedia.org/wiki/Pseudomembranous_colitishttp://en.wikipedia.org/wiki/Pseudomembranous_colitishttp://en.wikipedia.org/wiki/Human_florahttp://en.wikipedia.org/wiki/Clostridium_difficilehttp://en.wikipedia.org/wiki/Clostridium_difficilehttp://en.wikipedia.org/wiki/Laboratory_diagnosis_of_bacteriahttp://en.wikipedia.org/wiki/Laboratory_diagnosis_of_bacteriahttp://en.wikipedia.org/wiki/Transmission_(medicine)
  • 8/12/2019 Classification of Infectious Disease

    20/64

  • 8/12/2019 Classification of Infectious Disease

    21/64

    Species of human pathogenic bacteria

    Species Transmission Diseases Treatment Prevention laboratorydiagnosis

    Enterococcus

    faecalisandEnterococcusfaecium

    Part of human

    flora,opportunisticorentering throughGI tract orurinary systemwounds

    Nosocomial

    infections

    Penicillin and an

    aminoglycosideVancomycin

    Quinupristinanddalfopristin

    No vaccine

    Hand washingand othernosocomialprevention

    Culture in 6.5%

    NaClCan hydrolyzeesculininpresence of bile

    Escherichia coli(generally)

    Part of gut flora,spreading

    extraintestinallyor proliferating inthe GI tract

    Urinary tractinfections

    (UTI)

    Diarrhea

    Meningitis ininfants

    UTI:

    Co-trimoxazole

    Fluoroquinolone,e.g. ciprofloxacin

    Meningitis:

    Cephalosporinandgentamicincombination

    Diarrhea:

    Antibiotics aboveshorten duration

    Electrolyte and fluidreplacement

    (no vaccine orpreventive drug)

    Food and waterpreparation

    Hand washingand disinfection

    Culture onMacConkey agar

    and studycarbohydratefermentationpatterns: Lactosefermentation(most E. colistrains). Gasproduction inglucosefermentation

    Mannitolfermentation

    http://en.wikipedia.org/wiki/Transmission_(medicine)http://en.wikipedia.org/wiki/Laboratory_diagnosis_of_bacteriahttp://en.wikipedia.org/wiki/Laboratory_diagnosis_of_bacteriahttp://en.wikipedia.org/wiki/Enterococcus_faecalishttp://en.wikipedia.org/wiki/Enterococcus_faecalishttp://en.wikipedia.org/wiki/Enterococcus_faeciumhttp://en.wikipedia.org/wiki/Enterococcus_faeciumhttp://en.wikipedia.org/wiki/Opportunistic_infectionhttp://en.wikipedia.org/wiki/Aminoglycosidehttp://en.wikipedia.org/wiki/Vancomycinhttp://en.wikipedia.org/wiki/Quinupristinhttp://en.wikipedia.org/wiki/Dalfopristinhttp://en.wikipedia.org/wiki/Nosocomialhttp://en.wikipedia.org/wiki/Nosocomialhttp://en.wikipedia.org/wiki/Sodium_chloridehttp://en.wikipedia.org/wiki/Esculinhttp://en.wikipedia.org/wiki/Escherichia_colihttp://en.wikipedia.org/wiki/Gut_florahttp://en.wikipedia.org/wiki/Urinary_tract_infectionshttp://en.wikipedia.org/wiki/Urinary_tract_infectionshttp://en.wikipedia.org/wiki/Co-trimoxazolehttp://en.wikipedia.org/wiki/Fluoroquinolonehttp://en.wikipedia.org/wiki/Ciprofloxacinhttp://en.wikipedia.org/wiki/Cephalosporinhttp://en.wikipedia.org/wiki/Gentamicinhttp://en.wikipedia.org/wiki/MacConkey_agarhttp://en.wikipedia.org/wiki/MacConkey_agarhttp://en.wikipedia.org/wiki/Gentamicinhttp://en.wikipedia.org/wiki/Cephalosporinhttp://en.wikipedia.org/wiki/Ciprofloxacinhttp://en.wikipedia.org/wiki/Fluoroquinolonehttp://en.wikipedia.org/wiki/Co-trimoxazolehttp://en.wikipedia.org/wiki/Co-trimoxazolehttp://en.wikipedia.org/wiki/Co-trimoxazolehttp://en.wikipedia.org/wiki/Urinary_tract_infectionshttp://en.wikipedia.org/wiki/Urinary_tract_infectionshttp://en.wikipedia.org/wiki/Gut_florahttp://en.wikipedia.org/wiki/Escherichia_colihttp://en.wikipedia.org/wiki/Esculinhttp://en.wikipedia.org/wiki/Sodium_chloridehttp://en.wikipedia.org/wiki/Nosocomialhttp://en.wikipedia.org/wiki/Nosocomialhttp://en.wikipedia.org/wiki/Dalfopristinhttp://en.wikipedia.org/wiki/Quinupristinhttp://en.wikipedia.org/wiki/Vancomycinhttp://en.wikipedia.org/wiki/Aminoglycosidehttp://en.wikipedia.org/wiki/Opportunistic_infectionhttp://en.wikipedia.org/wiki/Enterococcus_faeciumhttp://en.wikipedia.org/wiki/Enterococcus_faeciumhttp://en.wikipedia.org/wiki/Enterococcus_faecalishttp://en.wikipedia.org/wiki/Enterococcus_faecalishttp://en.wikipedia.org/wiki/Laboratory_diagnosis_of_bacteriahttp://en.wikipedia.org/wiki/Laboratory_diagnosis_of_bacteriahttp://en.wikipedia.org/wiki/Transmission_(medicine)
  • 8/12/2019 Classification of Infectious Disease

    22/64

    Species of human pathogenic bacteria

    Species Transmission Diseases Treatment Prevention laboratorydiagnosis

    Francisella

    tularensis

    vector-borne by

    anthropods

    Infected wild ordomestic animals,birds or housepets

    Tularemia Streptomycin

    Gentamicin

    Avoiding insect vectors

    Precautions whenhandling wild animalsor animal products

    rarely cultured)

    Serology

    Haemophilus

    influenzae

    Droplet contact

    Human flora ofe.g. upperrespiratory tract

    Bacterial

    meningitisUpperrespiratory tractinfections

    Pneumonia,bronchitis

    Meningitis:

    (resistance-testsare required first)

    Third generationcephalosporin,e.g. cefotaximeorceftriaxone

    Ampicillinandsulbactam

    combination

    Hib vaccineto infants

    Rifampinprophylactically

    Culture on chocolate

    agarwith hemin(factor X) and NAD+(factor V)

    Quellung reaction

    Immunofluorescencestaining of capsule

    Detection of capsularantigen in CSFor

    other body fluids

    http://en.wikipedia.org/wiki/Transmission_(medicine)http://en.wikipedia.org/wiki/Laboratory_diagnosis_of_bacteriahttp://en.wikipedia.org/wiki/Laboratory_diagnosis_of_bacteriahttp://en.wikipedia.org/wiki/Francisella_tularensishttp://en.wikipedia.org/wiki/Francisella_tularensishttp://en.wikipedia.org/wiki/Vector_(epidemiology)http://en.wikipedia.org/wiki/Tularemiahttp://en.wikipedia.org/wiki/Streptomycinhttp://en.wikipedia.org/wiki/Gentamicinhttp://en.wikipedia.org/wiki/Haemophilus_influenzaehttp://en.wikipedia.org/wiki/Haemophilus_influenzaehttp://en.wikipedia.org/wiki/Upper_respiratory_tract_infectionhttp://en.wikipedia.org/wiki/Upper_respiratory_tract_infectionhttp://en.wikipedia.org/wiki/Upper_respiratory_tract_infectionhttp://en.wikipedia.org/wiki/Pneumoniahttp://en.wikipedia.org/wiki/Bronchitishttp://en.wikipedia.org/wiki/Cephalosporinhttp://en.wikipedia.org/wiki/Cephalosporinhttp://en.wikipedia.org/wiki/Cefotaximehttp://en.wikipedia.org/wiki/Ceftriaxonehttp://en.wikipedia.org/wiki/Ampicillinhttp://en.wikipedia.org/wiki/Sulbactamhttp://en.wikipedia.org/wiki/Hib_vaccinehttp://en.wikipedia.org/wiki/Rifampinhttp://en.wikipedia.org/wiki/Chocolate_agarhttp://en.wikipedia.org/wiki/Chocolate_agarhttp://en.wikipedia.org/wiki/Heminhttp://en.wikipedia.org/wiki/Nicotinamide_adenine_dinucleotidehttp://en.wikipedia.org/wiki/Quellung_reactionhttp://en.wikipedia.org/wiki/Immunofluorescencehttp://en.wikipedia.org/wiki/Cerebrospinal_fluidhttp://en.wikipedia.org/wiki/Cerebrospinal_fluidhttp://en.wikipedia.org/wiki/Immunofluorescencehttp://en.wikipedia.org/wiki/Quellung_reactionhttp://en.wikipedia.org/wiki/Nicotinamide_adenine_dinucleotidehttp://en.wikipedia.org/wiki/Heminhttp://en.wikipedia.org/wiki/Chocolate_agarhttp://en.wikipedia.org/wiki/Chocolate_agarhttp://en.wikipedia.org/wiki/Rifampinhttp://en.wikipedia.org/wiki/Hib_vaccinehttp://en.wikipedia.org/wiki/Sulbactamhttp://en.wikipedia.org/wiki/Ampicillinhttp://en.wikipedia.org/wiki/Ceftriaxonehttp://en.wikipedia.org/wiki/Cefotaximehttp://en.wikipedia.org/wiki/Cephalosporinhttp://en.wikipedia.org/wiki/Cephalosporinhttp://en.wikipedia.org/wiki/Bronchitishttp://en.wikipedia.org/wiki/Pneumoniahttp://en.wikipedia.org/wiki/Upper_respiratory_tract_infectionhttp://en.wikipedia.org/wiki/Upper_respiratory_tract_infectionhttp://en.wikipedia.org/wiki/Upper_respiratory_tract_infectionhttp://en.wikipedia.org/wiki/Haemophilus_influenzaehttp://en.wikipedia.org/wiki/Haemophilus_influenzaehttp://en.wikipedia.org/wiki/Gentamicinhttp://en.wikipedia.org/wiki/Streptomycinhttp://en.wikipedia.org/wiki/Tularemiahttp://en.wikipedia.org/wiki/Vector_(epidemiology)http://en.wikipedia.org/wiki/Francisella_tularensishttp://en.wikipedia.org/wiki/Francisella_tularensishttp://en.wikipedia.org/wiki/Laboratory_diagnosis_of_bacteriahttp://en.wikipedia.org/wiki/Laboratory_diagnosis_of_bacteriahttp://en.wikipedia.org/wiki/Transmission_(medicine)
  • 8/12/2019 Classification of Infectious Disease

    23/64

    Species of human pathogenic bacteria

    Species Transmission Diseases Treatment Prevention laboratory diagnosis

    Helicobacterpylori

    Colonizingstomach

    Unclearperson-to-persontransmission

    Peptic ulcer

    Risk factor forgastriccarcinomaandgastric B-celllymphoma

    Tetracycline,metronidazole

    and bismuth saltcombination

    (No vaccineor preventive

    drug)

    Microscopically Corkscrewmovement

    Urease-positivity byradioactively labeled urea

    Serology by ELISA

    Legionellapneumophila

    Dropletcontact, frome.g. coolingtowers,humidifiers, airconditionersand waterdistributionsystems

    Legionnaire'sDisease

    Pontiac fever

    Macrolides, e.g.erythromycinorazithromycin

    Fluoroquinolones

    (no vaccine orpreventivedrug)

    Heating water

    Culture from respiratorysecretions on buffered charcoalyeast extractenriched with L-cysteine, iron and -ketoglutarate

    Serology, including directimmunofluorescence andradioimmunoassay for antigenin urine

    Hybridization to ribosomal RNA

    using DNA probe

    http://en.wikipedia.org/wiki/Transmission_(medicine)http://en.wikipedia.org/wiki/Laboratory_diagnosis_of_bacteriahttp://en.wikipedia.org/wiki/Helicobacter_pylorihttp://en.wikipedia.org/wiki/Helicobacter_pylorihttp://en.wikipedia.org/wiki/Peptic_ulcerhttp://en.wikipedia.org/wiki/Gastric_carcinomahttp://en.wikipedia.org/wiki/Gastric_carcinomahttp://en.wikipedia.org/wiki/B-cell_lymphomahttp://en.wikipedia.org/wiki/B-cell_lymphomahttp://en.wikipedia.org/wiki/Tetracyclinehttp://en.wikipedia.org/wiki/Metronidazolehttp://en.wikipedia.org/wiki/Bismuth_salthttp://en.wikipedia.org/wiki/Ureasehttp://en.wikipedia.org/wiki/ELISAhttp://en.wikipedia.org/wiki/Legionella_pneumophilahttp://en.wikipedia.org/wiki/Legionella_pneumophilahttp://en.wikipedia.org/wiki/Cooling_towerhttp://en.wikipedia.org/wiki/Cooling_towerhttp://en.wikipedia.org/wiki/Humidifiershttp://en.wikipedia.org/wiki/Legionnaire's_Diseasehttp://en.wikipedia.org/wiki/Legionnaire's_Diseasehttp://en.wikipedia.org/wiki/Pontiac_feverhttp://en.wikipedia.org/wiki/Macrolidehttp://en.wikipedia.org/wiki/Erythromycinhttp://en.wikipedia.org/wiki/Azithromycinhttp://en.wikipedia.org/wiki/Fluoroquinolonehttp://en.wikipedia.org/wiki/Yeast_extracthttp://en.wikipedia.org/wiki/Cysteinehttp://en.wikipedia.org/wiki/Alpha-ketoglutaric_acidhttp://en.wikipedia.org/wiki/Alpha-ketoglutaric_acidhttp://en.wikipedia.org/wiki/Alpha-ketoglutaric_acidhttp://en.wikipedia.org/wiki/DNA_probehttp://en.wikipedia.org/wiki/DNA_probehttp://en.wikipedia.org/wiki/Alpha-ketoglutaric_acidhttp://en.wikipedia.org/wiki/Alpha-ketoglutaric_acidhttp://en.wikipedia.org/wiki/Alpha-ketoglutaric_acidhttp://en.wikipedia.org/wiki/Cysteinehttp://en.wikipedia.org/wiki/Yeast_extracthttp://en.wikipedia.org/wiki/Fluoroquinolonehttp://en.wikipedia.org/wiki/Azithromycinhttp://en.wikipedia.org/wiki/Erythromycinhttp://en.wikipedia.org/wiki/Macrolidehttp://en.wikipedia.org/wiki/Pontiac_feverhttp://en.wikipedia.org/wiki/Legionnaire's_Diseasehttp://en.wikipedia.org/wiki/Legionnaire's_Diseasehttp://en.wikipedia.org/wiki/Humidifiershttp://en.wikipedia.org/wiki/Cooling_towerhttp://en.wikipedia.org/wiki/Cooling_towerhttp://en.wikipedia.org/wiki/Legionella_pneumophilahttp://en.wikipedia.org/wiki/Legionella_pneumophilahttp://en.wikipedia.org/wiki/ELISAhttp://en.wikipedia.org/wiki/Ureasehttp://en.wikipedia.org/wiki/Bismuth_salthttp://en.wikipedia.org/wiki/Metronidazolehttp://en.wikipedia.org/wiki/Tetracyclinehttp://en.wikipedia.org/wiki/B-cell_lymphomahttp://en.wikipedia.org/wiki/B-cell_lymphomahttp://en.wikipedia.org/wiki/B-cell_lymphomahttp://en.wikipedia.org/wiki/B-cell_lymphomahttp://en.wikipedia.org/wiki/Gastric_carcinomahttp://en.wikipedia.org/wiki/Gastric_carcinomahttp://en.wikipedia.org/wiki/Peptic_ulcerhttp://en.wikipedia.org/wiki/Helicobacter_pylorihttp://en.wikipedia.org/wiki/Helicobacter_pylorihttp://en.wikipedia.org/wiki/Laboratory_diagnosis_of_bacteriahttp://en.wikipedia.org/wiki/Transmission_(medicine)
  • 8/12/2019 Classification of Infectious Disease

    24/64

    Species of human pathogenic bacteria

    Species Transmission Diseases Treatment Prevention laboratorydiagnosis

    Leptospira

    interrogans

    Food and water

    contaminatedby e.g. urinefrom wild ordomesticanimals.Leptospirasurvives forweeks instagnant water

    Leptospirosis Penicillin G

    Tetracycline,e.g.doxycycline

    (no vaccine)

    Doxycycline

    Prevention ofexposure

    Rodent control

    Dark-field microscopy

    on fresh blood smear(but doesn't stainwell)

    Serologicagglutionation tests

    Listeriamonocytogenes

    Dairy products,ground meats,poultry

    Verticalto

    newborn orfetus

    Listeriosis Ampicillin

    Co-trimoxazole

    (no vaccine)

    Proper foodpreparation andhandling

    Isolation from e.g.blood and CSF

    Beta-hemolysisandcatalase production

    on blood agarMicroscopy formorphology andmotility

    http://en.wikipedia.org/wiki/Transmission_(medicine)http://en.wikipedia.org/wiki/Laboratory_diagnosis_of_bacteriahttp://en.wikipedia.org/wiki/Laboratory_diagnosis_of_bacteriahttp://en.wikipedia.org/wiki/Leptospira_interroganshttp://en.wikipedia.org/wiki/Leptospira_interroganshttp://en.wikipedia.org/wiki/Leptospirosishttp://en.wikipedia.org/wiki/Penicillin_Ghttp://en.wikipedia.org/wiki/Tetracyclinehttp://en.wikipedia.org/wiki/Doxycyclinehttp://en.wikipedia.org/wiki/Doxycyclinehttp://en.wikipedia.org/w/index.php?title=Rodent_control&action=edit&redlink=1http://en.wikipedia.org/w/index.php?title=Rodent_control&action=edit&redlink=1http://en.wikipedia.org/wiki/Dark-field_microscopyhttp://en.wikipedia.org/wiki/Listeria_monocytogeneshttp://en.wikipedia.org/wiki/Listeria_monocytogeneshttp://en.wikipedia.org/wiki/Transmission_(medicine)http://en.wikipedia.org/wiki/Listeriosishttp://en.wikipedia.org/wiki/Ampicillinhttp://en.wikipedia.org/wiki/Co-trimoxazolehttp://en.wikipedia.org/wiki/Cerebrospinal_fluidhttp://en.wikipedia.org/wiki/Beta-hemolysishttp://en.wikipedia.org/wiki/Beta-hemolysishttp://en.wikipedia.org/wiki/Beta-hemolysishttp://en.wikipedia.org/wiki/Beta-hemolysishttp://en.wikipedia.org/wiki/Cerebrospinal_fluidhttp://en.wikipedia.org/wiki/Co-trimoxazolehttp://en.wikipedia.org/wiki/Co-trimoxazolehttp://en.wikipedia.org/wiki/Co-trimoxazolehttp://en.wikipedia.org/wiki/Ampicillinhttp://en.wikipedia.org/wiki/Listeriosishttp://en.wikipedia.org/wiki/Transmission_(medicine)http://en.wikipedia.org/wiki/Listeria_monocytogeneshttp://en.wikipedia.org/wiki/Listeria_monocytogeneshttp://en.wikipedia.org/wiki/Dark-field_microscopyhttp://en.wikipedia.org/wiki/Dark-field_microscopyhttp://en.wikipedia.org/wiki/Dark-field_microscopyhttp://en.wikipedia.org/w/index.php?title=Rodent_control&action=edit&redlink=1http://en.wikipedia.org/w/index.php?title=Rodent_control&action=edit&redlink=1http://en.wikipedia.org/wiki/Doxycyclinehttp://en.wikipedia.org/wiki/Doxycyclinehttp://en.wikipedia.org/wiki/Tetracyclinehttp://en.wikipedia.org/wiki/Penicillin_Ghttp://en.wikipedia.org/wiki/Leptospirosishttp://en.wikipedia.org/wiki/Leptospira_interroganshttp://en.wikipedia.org/wiki/Leptospira_interroganshttp://en.wikipedia.org/wiki/Laboratory_diagnosis_of_bacteriahttp://en.wikipedia.org/wiki/Laboratory_diagnosis_of_bacteriahttp://en.wikipedia.org/wiki/Transmission_(medicine)
  • 8/12/2019 Classification of Infectious Disease

    25/64

    Species of human pathogenic bacteria

    Species Transmission Diseases Treatment Prevention

    laboratory diagnosis

    Mycobacteriumleprae

    Prolongedhuman-humancontact, e.g.throughexudates fromskin lesions toabrasion ofother person

    Leprosy(Hansen'sdisease)

    Tuberculoid form:

    Dapsoneand rifampin

    Lepromatous form:

    Clofazimine

    BCGvaccineshowssomeeffects

    Tuberculoid form:

    Hard to isolate (diagnosison clinical findings andhistology of biopsies)

    Lepromatous form:

    Acid-faststaining frome.g. skin scrapings

    Mycobacterium

    tuberculosis

    Droplet contact Tuberculosis Standard "short"

    course:

    First 2 months,combination: IsoniazidRifampicinPyrazinamideEthambutol

    Further 4 months,combination: Isoniazid

    Rifampicin

    BCG

    vaccine

    Isoniazid

    Ziehl-Neelsenstain

    showing acid-fastbacteria

    Hybridization probesforDNA, succeeded by PCR

    Culture on Lowenstein-Jensenagar

    http://en.wikipedia.org/wiki/Transmission_(medicine)http://en.wikipedia.org/wiki/Laboratory_diagnosis_of_bacteriahttp://en.wikipedia.org/wiki/Mycobacterium_lepraehttp://en.wikipedia.org/wiki/Mycobacterium_lepraehttp://en.wikipedia.org/wiki/Leprosyhttp://en.wikipedia.org/wiki/Dapsonehttp://en.wikipedia.org/wiki/Rifampinhttp://en.wikipedia.org/wiki/Clofaziminehttp://en.wikipedia.org/wiki/Clofaziminehttp://en.wikipedia.org/wiki/Bacillus_Calmette-Gu%C3%A9rinhttp://en.wikipedia.org/wiki/Bacillus_Calmette-Gu%C3%A9rinhttp://en.wikipedia.org/wiki/Acid-fasthttp://en.wikipedia.org/wiki/Acid-fasthttp://en.wikipedia.org/wiki/Mycobacterium_tuberculosishttp://en.wikipedia.org/wiki/Mycobacterium_tuberculosishttp://en.wikipedia.org/wiki/Tuberculosishttp://en.wikipedia.org/wiki/Isoniazidhttp://en.wikipedia.org/wiki/Rifampicinhttp://en.wikipedia.org/wiki/Pyrazinamidehttp://en.wikipedia.org/wiki/Ethambutolhttp://en.wikipedia.org/wiki/Isoniazidhttp://en.wikipedia.org/wiki/Rifampicinhttp://en.wikipedia.org/wiki/Bacillus_Calmette-Gu%C3%A9rinhttp://en.wikipedia.org/wiki/Bacillus_Calmette-Gu%C3%A9rinhttp://en.wikipedia.org/wiki/Isoniazidhttp://en.wikipedia.org/wiki/Ziehl-Neelsenhttp://en.wikipedia.org/wiki/Acid-fasthttp://en.wikipedia.org/wiki/Hybridization_probehttp://en.wikipedia.org/wiki/Polymerase_chain_reactionhttp://en.wikipedia.org/wiki/Lowenstein-Jensenhttp://en.wikipedia.org/wiki/Lowenstein-Jensenhttp://en.wikipedia.org/wiki/Lowenstein-Jensenhttp://en.wikipedia.org/wiki/Lowenstein-Jensenhttp://en.wikipedia.org/wiki/Lowenstein-Jensenhttp://en.wikipedia.org/wiki/Polymerase_chain_reactionhttp://en.wikipedia.org/wiki/Hybridization_probehttp://en.wikipedia.org/wiki/Acid-fasthttp://en.wikipedia.org/wiki/Acid-fasthttp://en.wikipedia.org/wiki/Acid-fasthttp://en.wikipedia.org/wiki/Ziehl-Neelsenhttp://en.wikipedia.org/wiki/Ziehl-Neelsenhttp://en.wikipedia.org/wiki/Ziehl-Neelsenhttp://en.wikipedia.org/wiki/Isoniazidhttp://en.wikipedia.org/wiki/Bacillus_Calmette-Gu%C3%A9rinhttp://en.wikipedia.org/wiki/Bacillus_Calmette-Gu%C3%A9rinhttp://en.wikipedia.org/wiki/Rifampicinhttp://en.wikipedia.org/wiki/Isoniazidhttp://en.wikipedia.org/wiki/Ethambutolhttp://en.wikipedia.org/wiki/Pyrazinamidehttp://en.wikipedia.org/wiki/Rifampicinhttp://en.wikipedia.org/wiki/Isoniazidhttp://en.wikipedia.org/wiki/Tuberculosishttp://en.wikipedia.org/wiki/Mycobacterium_tuberculosishttp://en.wikipedia.org/wiki/Mycobacterium_tuberculosishttp://en.wikipedia.org/wiki/Acid-fasthttp://en.wikipedia.org/wiki/Acid-fasthttp://en.wikipedia.org/wiki/Acid-fasthttp://en.wikipedia.org/wiki/Acid-fasthttp://en.wikipedia.org/wiki/Bacillus_Calmette-Gu%C3%A9rinhttp://en.wikipedia.org/wiki/Bacillus_Calmette-Gu%C3%A9rinhttp://en.wikipedia.org/wiki/Clofaziminehttp://en.wikipedia.org/wiki/Clofaziminehttp://en.wikipedia.org/wiki/Rifampinhttp://en.wikipedia.org/wiki/Dapsonehttp://en.wikipedia.org/wiki/Leprosyhttp://en.wikipedia.org/wiki/Mycobacterium_lepraehttp://en.wikipedia.org/wiki/Mycobacterium_lepraehttp://en.wikipedia.org/wiki/Laboratory_diagnosis_of_bacteriahttp://en.wikipedia.org/wiki/Transmission_(medicine)
  • 8/12/2019 Classification of Infectious Disease

    26/64

    Species of human pathogenic bacteria

    Species Transmission Diseases Treatment Prevention laboratorydiagnosis

    Mycoplasma

    pneumoniae

    Human flora

    Droplet contact

    Mycoplasma

    pneumonia

    Doxycyclineand

    erythromycin

    (difficult to culture)

    Serologic tests, e.g.complement fixationtest

    DNA probesonsputum specimens

    Neisseriameningitidis

    Respiratorydroplets

    Meningococcaldiseaseincluding

    meningitis

    Waterhouse-Friderichsensyndrome

    Penicillin G

    Cefotaxime

    Ceftriaxone

    NmVac4-A/C/Y/W-

    135vaccine

    Rifampin

    Microscopy showinggram-negative

    diplococci, often withPMNs

    Culture on chocolateagar, giving positiveoxidase testandfermentation ofglucose and maltosein 5% CO2 in air

    http://en.wikipedia.org/wiki/Transmission_(medicine)http://en.wikipedia.org/wiki/Laboratory_diagnosis_of_bacteriahttp://en.wikipedia.org/wiki/Laboratory_diagnosis_of_bacteriahttp://en.wikipedia.org/wiki/Mycoplasma_pneumoniaehttp://en.wikipedia.org/wiki/Mycoplasma_pneumoniaehttp://en.wikipedia.org/wiki/Mycoplasma_pneumoniahttp://en.wikipedia.org/wiki/Mycoplasma_pneumoniahttp://en.wikipedia.org/wiki/Doxycyclinehttp://en.wikipedia.org/wiki/Erythromycinhttp://en.wikipedia.org/wiki/Complement_fixation_testhttp://en.wikipedia.org/wiki/Complement_fixation_testhttp://en.wikipedia.org/wiki/DNA_probeshttp://en.wikipedia.org/wiki/Neisseria_meningitidishttp://en.wikipedia.org/wiki/Neisseria_meningitidishttp://en.wikipedia.org/wiki/Meningococcal_diseasehttp://en.wikipedia.org/wiki/Meningococcal_diseasehttp://en.wikipedia.org/wiki/Waterhouse-Friderichsen_syndromehttp://en.wikipedia.org/wiki/Waterhouse-Friderichsen_syndromehttp://en.wikipedia.org/wiki/Waterhouse-Friderichsen_syndromehttp://en.wikipedia.org/wiki/Penicillin_Ghttp://en.wikipedia.org/wiki/Cefotaximehttp://en.wikipedia.org/wiki/Ceftriaxonehttp://en.wikipedia.org/wiki/NmVac4-A/C/Y/W-135http://en.wikipedia.org/wiki/NmVac4-A/C/Y/W-135http://en.wikipedia.org/wiki/NmVac4-A/C/Y/W-135http://en.wikipedia.org/wiki/Rifampinhttp://en.wikipedia.org/wiki/Polymorphonuclear_leukocyteshttp://en.wikipedia.org/wiki/Chocolate_agarhttp://en.wikipedia.org/wiki/Chocolate_agarhttp://en.wikipedia.org/wiki/Oxidase_testhttp://en.wikipedia.org/wiki/Oxidase_testhttp://en.wikipedia.org/wiki/Chocolate_agarhttp://en.wikipedia.org/wiki/Chocolate_agarhttp://en.wikipedia.org/wiki/Polymorphonuclear_leukocyteshttp://en.wikipedia.org/wiki/Rifampinhttp://en.wikipedia.org/wiki/NmVac4-A/C/Y/W-135http://en.wikipedia.org/wiki/NmVac4-A/C/Y/W-135http://en.wikipedia.org/wiki/NmVac4-A/C/Y/W-135http://en.wikipedia.org/wiki/NmVac4-A/C/Y/W-135http://en.wikipedia.org/wiki/NmVac4-A/C/Y/W-135http://en.wikipedia.org/wiki/Ceftriaxonehttp://en.wikipedia.org/wiki/Cefotaximehttp://en.wikipedia.org/wiki/Penicillin_Ghttp://en.wikipedia.org/wiki/Waterhouse-Friderichsen_syndromehttp://en.wikipedia.org/wiki/Waterhouse-Friderichsen_syndromehttp://en.wikipedia.org/wiki/Waterhouse-Friderichsen_syndromehttp://en.wikipedia.org/wiki/Waterhouse-Friderichsen_syndromehttp://en.wikipedia.org/wiki/Meningococcal_diseasehttp://en.wikipedia.org/wiki/Meningococcal_diseasehttp://en.wikipedia.org/wiki/Neisseria_meningitidishttp://en.wikipedia.org/wiki/Neisseria_meningitidishttp://en.wikipedia.org/wiki/DNA_probeshttp://en.wikipedia.org/wiki/Complement_fixation_testhttp://en.wikipedia.org/wiki/Complement_fixation_testhttp://en.wikipedia.org/wiki/Erythromycinhttp://en.wikipedia.org/wiki/Doxycyclinehttp://en.wikipedia.org/wiki/Mycoplasma_pneumoniahttp://en.wikipedia.org/wiki/Mycoplasma_pneumoniahttp://en.wikipedia.org/wiki/Mycoplasma_pneumoniaehttp://en.wikipedia.org/wiki/Mycoplasma_pneumoniaehttp://en.wikipedia.org/wiki/Laboratory_diagnosis_of_bacteriahttp://en.wikipedia.org/wiki/Laboratory_diagnosis_of_bacteriahttp://en.wikipedia.org/wiki/Transmission_(medicine)
  • 8/12/2019 Classification of Infectious Disease

    27/64

    Species of human pathogenic bacteria

    Species Transmission Diseases Treatment Prevention laboratorydiagnosis

    Pseudomonas

    aeruginosa

    Infects

    damagedtissues orpeople withreducedimmunity

    Pseudomonas infection

    Localized to eye, ear,skin, urinary,respiratory orgastrointestinal tract orCNS, or systemic withbacteremia, secondarypneumonia bone and

    joint infections,endocarditis, skin, softtissue or CNSinfections.

    Aminoglycoside

    and anti-pseudomonal -lactam

    (no vaccine)

    Topical silversulfadiazineforburn wounds

    Colourless

    colonies onMacConkey agar.

    Production ofpyocyanineandfluorescein

    Positive oxidasetest. No lactosefermentation.

    Rickettsiarickettsii

    Bite of infectedwoodor dog

    tick

    Rocky mountainspotted fever

    Doxycycline

    Chloramphenicol

    no preventivedrug or approved

    vaccine)Vector control,such as clothing

    Prompt removal ofattached ticks

    Serology

    Immunofluoresce

    nceagainstRickettsiaantigens

    http://en.wikipedia.org/wiki/Transmission_(medicine)http://en.wikipedia.org/wiki/Laboratory_diagnosis_of_bacteriahttp://en.wikipedia.org/wiki/Laboratory_diagnosis_of_bacteriahttp://en.wikipedia.org/wiki/Pseudomonas_aeruginosahttp://en.wikipedia.org/wiki/Pseudomonas_aeruginosahttp://en.wikipedia.org/wiki/Pseudomonas_infectionhttp://en.wikipedia.org/wiki/Aminoglycosidehttp://en.wikipedia.org/wiki/Beta-lactamhttp://en.wikipedia.org/wiki/Beta-lactamhttp://en.wikipedia.org/wiki/Beta-lactamhttp://en.wikipedia.org/wiki/Silver_sulfadiazinehttp://en.wikipedia.org/wiki/Silver_sulfadiazinehttp://en.wikipedia.org/wiki/MacConkey_agarhttp://en.wikipedia.org/wiki/Pyocyaninehttp://en.wikipedia.org/wiki/Fluoresceinhttp://en.wikipedia.org/wiki/Oxidase_testhttp://en.wikipedia.org/wiki/Oxidase_testhttp://en.wikipedia.org/wiki/Rickettsia_rickettsiihttp://en.wikipedia.org/wiki/Rickettsia_rickettsiihttp://en.wikipedia.org/wiki/Dermacentor_variabilishttp://en.wikipedia.org/wiki/Rhipicephalus_sanguineushttp://en.wikipedia.org/wiki/Rhipicephalus_sanguineushttp://en.wikipedia.org/wiki/Rocky_mountain_spotted_feverhttp://en.wikipedia.org/wiki/Rocky_mountain_spotted_feverhttp://en.wikipedia.org/wiki/Doxycyclinehttp://en.wikipedia.org/wiki/Chloramphenicolhttp://en.wikipedia.org/wiki/Immunofluorescencehttp://en.wikipedia.org/wiki/Immunofluorescencehttp://en.wikipedia.org/wiki/Immunofluorescencehttp://en.wikipedia.org/wiki/Immunofluorescencehttp://en.wikipedia.org/wiki/Chloramphenicolhttp://en.wikipedia.org/wiki/Doxycyclinehttp://en.wikipedia.org/wiki/Rocky_mountain_spotted_feverhttp://en.wikipedia.org/wiki/Rocky_mountain_spotted_feverhttp://en.wikipedia.org/wiki/Rhipicephalus_sanguineushttp://en.wikipedia.org/wiki/Rhipicephalus_sanguineushttp://en.wikipedia.org/wiki/Dermacentor_variabilishttp://en.wikipedia.org/wiki/Rickettsia_rickettsiihttp://en.wikipedia.org/wiki/Rickettsia_rickettsiihttp://en.wikipedia.org/wiki/Oxidase_testhttp://en.wikipedia.org/wiki/Oxidase_testhttp://en.wikipedia.org/wiki/Fluoresceinhttp://en.wikipedia.org/wiki/Pyocyaninehttp://en.wikipedia.org/wiki/MacConkey_agarhttp://en.wikipedia.org/wiki/Silver_sulfadiazinehttp://en.wikipedia.org/wiki/Silver_sulfadiazinehttp://en.wikipedia.org/wiki/Beta-lactamhttp://en.wikipedia.org/wiki/Beta-lactamhttp://en.wikipedia.org/wiki/Beta-lactamhttp://en.wikipedia.org/wiki/Aminoglycosidehttp://en.wikipedia.org/wiki/Pseudomonas_infectionhttp://en.wikipedia.org/wiki/Pseudomonas_aeruginosahttp://en.wikipedia.org/wiki/Pseudomonas_aeruginosahttp://en.wikipedia.org/wiki/Laboratory_diagnosis_of_bacteriahttp://en.wikipedia.org/wiki/Laboratory_diagnosis_of_bacteriahttp://en.wikipedia.org/wiki/Transmission_(medicine)
  • 8/12/2019 Classification of Infectious Disease

    28/64

    Species of human pathogenic bacteria

    Species Transmission Diseases Treatment Prevention laboratorydiagnosis

    Salmonella typhi Human-human

    Fecal-oralthrough foodor water

    Typhoid fevertypesalmonellosis(dysentery,colitis)

    Ceftriaxone

    Fluoroquinolones,e.g. ciprofloxacin

    Ty21aandViCPSvaccines

    Hygiene andfood preparation

    Isolation from blood,feces, bone marrow,urine or rose spots onskin

    Colorless, non-lactosefermenting colonieson MacConkey agar

    Serology forantibodies against O

    antigen

    Salmonellatyphimurium

    Fecal-oral

    Foodcontaminated

    by fowl (e.g.eggs), petsand otheranimals

    Salmonellosiswithgastroenteritisandenterocolitis

    Fluid andelectrolytereplacement forsevere diarrhea

    Antibiotics (inimmunocompromised to preventsystemic spread)

    (No vaccine orpreventive drug)

    Proper sewage

    disposalFood preparation

    Good personalhygiene

    Colourless colonies onMacConkey agar

    http://en.wikipedia.org/wiki/Transmission_(medicine)http://en.wikipedia.org/wiki/Laboratory_diagnosis_of_bacteriahttp://en.wikipedia.org/wiki/Laboratory_diagnosis_of_bacteriahttp://en.wikipedia.org/wiki/Salmonella_typhihttp://en.wikipedia.org/wiki/Typhoid_feverhttp://en.wikipedia.org/wiki/Salmonellosishttp://en.wikipedia.org/wiki/Ceftriaxonehttp://en.wikipedia.org/wiki/Fluoroquinoloneshttp://en.wikipedia.org/wiki/Ciprofloxacinhttp://en.wikipedia.org/wiki/Ty21ahttp://en.wikipedia.org/wiki/Vi_capsular_polysaccharide_vaccinehttp://en.wikipedia.org/wiki/MacConkey_agarhttp://en.wikipedia.org/wiki/O_antigenhttp://en.wikipedia.org/wiki/O_antigenhttp://en.wikipedia.org/wiki/Salmonella_typhimuriumhttp://en.wikipedia.org/wiki/Salmonella_typhimuriumhttp://en.wikipedia.org/wiki/Salmonellosishttp://en.wikipedia.org/wiki/Gastroenteritishttp://en.wikipedia.org/wiki/Enterocolitishttp://en.wikipedia.org/wiki/MacConkey_agarhttp://en.wikipedia.org/wiki/MacConkey_agarhttp://en.wikipedia.org/wiki/Enterocolitishttp://en.wikipedia.org/wiki/Gastroenteritishttp://en.wikipedia.org/wiki/Salmonellosishttp://en.wikipedia.org/wiki/Salmonella_typhimuriumhttp://en.wikipedia.org/wiki/Salmonella_typhimuriumhttp://en.wikipedia.org/wiki/O_antigenhttp://en.wikipedia.org/wiki/O_antigenhttp://en.wikipedia.org/wiki/MacConkey_agarhttp://en.wikipedia.org/wiki/Vi_capsular_polysaccharide_vaccinehttp://en.wikipedia.org/wiki/Ty21ahttp://en.wikipedia.org/wiki/Ciprofloxacinhttp://en.wikipedia.org/wiki/Fluoroquinoloneshttp://en.wikipedia.org/wiki/Ceftriaxonehttp://en.wikipedia.org/wiki/Salmonellosishttp://en.wikipedia.org/wiki/Typhoid_feverhttp://en.wikipedia.org/wiki/Salmonella_typhihttp://en.wikipedia.org/wiki/Laboratory_diagnosis_of_bacteriahttp://en.wikipedia.org/wiki/Laboratory_diagnosis_of_bacteriahttp://en.wikipedia.org/wiki/Transmission_(medicine)
  • 8/12/2019 Classification of Infectious Disease

    29/64

    Species of human pathogenic bacteria

    Species Transmission Diseases Treatment Prevention laboratorydiagnosis

    Shigella sonnei Fecal-oral

    FliesContaminatedfood or water

    Bacillarydysentery/Shigellosis

    Ciprofloxacinorazithromycin

    Protection ofwater andfood supplies

    Vaccines arein trial stage

    Culture onHektoen agarorother media forintestinalpathogens

    Staphylococcusaureus

    Human floraon mucosaein e.g.anterior nares

    and vagina,enteringthroughwound

    Coagulase-positivestaphylococcal infections:

    Localized skin infections

    Diffuse skin infection(Impetigo)

    Deep, localized infections

    Acute infective endocarditis

    Septicemia

    Necrotizing pneumonia

    ToxinosesToxic shocksyndrome

    Staphylococcal foodpoisoning

    Incision anddrainage oflocalized lesions

    Nafcillinand

    oxacillinVancomycinforMethicillin-resistant(MRSA)

    (no vaccine orpreventivedrug)

    Barrier

    precautions,washinghands andfomitedisinfection inhospitals

    Microscopyshowing stronglypositive Gramstainedcells in

    grape-like clustersPositive Catalasetestandcoagulase test

    Culture onenriched mediaproducing deepyellow, hemolytic

    colonies

    http://en.wikipedia.org/wiki/Transmission_(medicine)http://en.wikipedia.org/wiki/Laboratory_diagnosis_of_bacteriahttp://en.wikipedia.org/wiki/Laboratory_diagnosis_of_bacteriahttp://en.wikipedia.org/wiki/Shigella_sonneihttp://en.wikipedia.org/wiki/Shigellosishttp://en.wikipedia.org/wiki/Shigellosishttp://en.wikipedia.org/wiki/Ciprofloxacinhttp://en.wikipedia.org/wiki/Azithromycinhttp://en.wikipedia.org/wiki/Hektoen_agarhttp://en.wikipedia.org/wiki/Staphylococcus_aureushttp://en.wikipedia.org/wiki/Staphylococcus_aureushttp://en.wikipedia.org/wiki/Mucous_membranehttp://en.wikipedia.org/wiki/Nareshttp://en.wikipedia.org/wiki/Staphylococcal_infectionhttp://en.wikipedia.org/wiki/Impetigohttp://en.wikipedia.org/wiki/Infective_endocarditishttp://en.wikipedia.org/wiki/Septicemiahttp://en.wikipedia.org/wiki/Necrotizing_pneumoniahttp://en.wikipedia.org/wiki/Toxinoseshttp://en.wikipedia.org/wiki/Toxic_shock_syndromehttp://en.wikipedia.org/wiki/Toxic_shock_syndromehttp://en.wikipedia.org/wiki/Staphylococcal_food_poisoninghttp://en.wikipedia.org/wiki/Staphylococcal_food_poisoninghttp://en.wikipedia.org/wiki/Nafcillinhttp://en.wikipedia.org/wiki/Oxacillinhttp://en.wikipedia.org/wiki/Vancomycinhttp://en.wikipedia.org/wiki/Methicillin-resistant_Staphylococcus_aureushttp://en.wikipedia.org/wiki/Methicillin-resistant_Staphylococcus_aureushttp://en.wikipedia.org/wiki/Methicillin-resistant_Staphylococcus_aureushttp://en.wikipedia.org/wiki/Fomitehttp://en.wikipedia.org/wiki/Gram_staininghttp://en.wikipedia.org/wiki/Gram_staininghttp://en.wikipedia.org/wiki/Catalasehttp://en.wikipedia.org/wiki/Catalasehttp://en.wikipedia.org/wiki/Coagulase_testhttp://en.wikipedia.org/wiki/Coagulase_testhttp://en.wikipedia.org/wiki/Catalasehttp://en.wikipedia.org/wiki/Catalasehttp://en.wikipedia.org/wiki/Gram_staininghttp://en.wikipedia.org/wiki/Gram_staininghttp://en.wikipedia.org/wiki/Fomitehttp://en.wikipedia.org/wiki/Methicillin-resistant_Staphylococcus_aureushttp://en.wikipedia.org/wiki/Methicillin-resistant_Staphylococcus_aureushttp://en.wikipedia.org/wiki/Methicillin-resistant_Staphylococcus_aureushttp://en.wikipedia.org/wiki/Methicillin-resistant_Staphylococcus_aureushttp://en.wikipedia.org/wiki/Vancomycinhttp://en.wikipedia.org/wiki/Oxacillinhttp://en.wikipedia.org/wiki/Nafcillinhttp://en.wikipedia.org/wiki/Staphylococcal_food_poisoninghttp://en.wikipedia.org/wiki/Staphylococcal_food_poisoninghttp://en.wikipedia.org/wiki/Toxic_shock_syndromehttp://en.wikipedia.org/wiki/Toxic_shock_syndromehttp://en.wikipedia.org/wiki/Toxinoseshttp://en.wikipedia.org/wiki/Necrotizing_pneumoniahttp://en.wikipedia.org/wiki/Septicemiahttp://en.wikipedia.org/wiki/Infective_endocarditishttp://en.wikipedia.org/wiki/Impetigohttp://en.wikipedia.org/wiki/Staphylococcal_infectionhttp://en.wikipedia.org/wiki/Nareshttp://en.wikipedia.org/wiki/Mucous_membranehttp://en.wikipedia.org/wiki/Staphylococcus_aureushttp://en.wikipedia.org/wiki/Staphylococcus_aureushttp://en.wikipedia.org/wiki/Hektoen_agarhttp://en.wikipedia.org/wiki/Azithromycinhttp://en.wikipedia.org/wiki/Ciprofloxacinhttp://en.wikipedia.org/wiki/Shigellosishttp://en.wikipedia.org/wiki/Shigellosishttp://en.wikipedia.org/wiki/Shigella_sonneihttp://en.wikipedia.org/wiki/Laboratory_diagnosis_of_bacteriahttp://en.wikipedia.org/wiki/Laboratory_diagnosis_of_bacteriahttp://en.wikipedia.org/wiki/Transmission_(medicine)
  • 8/12/2019 Classification of Infectious Disease

    30/64

    Species of human pathogenic bacteria

    Species Transmission Diseases Treatment Prevention laboratory diagnosis

    Staphylococcusepidermidis

    Human flora inskin andanterior nares

    Infections ofimplantedprostheses, e.g.heart valves andcatheters

    Vancomycin None Microscopy showing stronglypositive Gram stainedcells ingrape-like clusters

    Positive Catalase testbutnegative coagulase test

    Novobiocin-sensitivity (S.epidermidis)

    Novobiocin-resistance (S.saprophyticus)

    Culture on enriched mediaproducing white, nonhemolyticcolonies

    Streptococcus

    pneumoniae

    Respiratory

    dropletsOften humanflora innasopharynx(spreading inimmunocompromised)

    Acute bacterial

    pneumonia&meningitisinadults

    Otitis mediaandsinusitisinchildren

    Penicillin G

    Vancomycinfor resistantstrains

    23-serotype

    vaccine foradults (PPV)

    Heptavalentconjugatedvaccine forchildren (PCV)

    Microscopy showing gram-

    positive, encapsulated lancet-shaped diplococci

    -hemolysison blood agar, bile-soluble, optochin-sensitive

    Positive Quellung reaction

    http://en.wikipedia.org/wiki/Transmission_(medicine)http://en.wikipedia.org/wiki/Laboratory_diagnosis_of_bacteriahttp://en.wikipedia.org/wiki/Staphylococcus_epidermidishttp://en.wikipedia.org/wiki/Staphylococcus_epidermidishttp://en.wikipedia.org/wiki/Prosthesishttp://en.wikipedia.org/wiki/Vancomycinhttp://en.wikipedia.org/wiki/Gram_staininghttp://en.wikipedia.org/wiki/Catalasehttp://en.wikipedia.org/wiki/Coagulase_testhttp://en.wikipedia.org/wiki/Novobiocinhttp://en.wikipedia.org/wiki/Novobiocinhttp://en.wikipedia.org/wiki/Streptococcus_pneumoniaehttp://en.wikipedia.org/wiki/Streptococcus_pneumoniaehttp://en.wikipedia.org/wiki/Bacterial_pneumoniahttp://en.wikipedia.org/wiki/Bacterial_pneumoniahttp://en.wikipedia.org/wiki/Meningitishttp://en.wikipedia.org/wiki/Otitis_mediahttp://en.wikipedia.org/wiki/Sinusitishttp://en.wikipedia.org/wiki/Penicillin_Ghttp://en.wikipedia.org/wiki/Vancomycinhttp://en.wikipedia.org/wiki/Pneumococcal_polysaccharide_vaccinehttp://en.wikipedia.org/wiki/Pneumococcal_conjugate_vaccinehttp://en.wikipedia.org/wiki/Gram-positivehttp://en.wikipedia.org/wiki/Gram-positivehttp://en.wikipedia.org/wiki/Hemolysis_(microbiology)http://en.wikipedia.org/wiki/Hemolysis_(microbiology)http://en.wikipedia.org/wiki/Quellung_reactionhttp://en.wikipedia.org/wiki/Quellung_reactionhttp://en.wikipedia.org/wiki/Hemolysis_(microbiology)http://en.wikipedia.org/wiki/Hemolysis_(microbiology)http://en.wikipedia.org/wiki/Hemolysis_(microbiology)http://en.wikipedia.org/wiki/Gram-positivehttp://en.wikipedia.org/wiki/Gram-positivehttp://en.wikipedia.org/wiki/Gram-positivehttp://en.wikipedia.org/wiki/Pneumococcal_conjugate_vaccinehttp://en.wikipedia.org/wiki/Pneumococcal_polysaccharide_vaccinehttp://en.wikipedia.org/wiki/Vancomycinhttp://en.wikipedia.org/wiki/Penicillin_Ghttp://en.wikipedia.org/wiki/Sinusitishttp://en.wikipedia.org/wiki/Otitis_mediahttp://en.wikipedia.org/wiki/Meningitishttp://en.wikipedia.org/wiki/Bacterial_pneumoniahttp://en.wikipedia.org/wiki/Bacterial_pneumoniahttp://en.wikipedia.org/wiki/Streptococcus_pneumoniaehttp://en.wikipedia.org/wiki/Streptococcus_pneumoniaehttp://en.wikipedia.org/wiki/Novobiocinhttp://en.wikipedia.org/wiki/Novobiocinhttp://en.wikipedia.org/wiki/Coagulase_testhttp://en.wikipedia.org/wiki/Catalasehttp://en.wikipedia.org/wiki/Gram_staininghttp://en.wikipedia.org/wiki/Vancomycinhttp://en.wikipedia.org/wiki/Prosthesishttp://en.wikipedia.org/wiki/Staphylococcus_epidermidishttp://en.wikipedia.org/wiki/Staphylococcus_epidermidishttp://en.wikipedia.org/wiki/Laboratory_diagnosis_of_bacteriahttp://en.wikipedia.org/wiki/Transmission_(medicine)
  • 8/12/2019 Classification of Infectious Disease

    31/64

    Species of human pathogenic bacteria

    Species Transmission Diseases Treatment Prevention laboratorydiagnosis

    Streptococcus

    pyogenes

    Respiratory

    dropletsDirect physicalcontact withimpetigolesions

    Streptococcal

    pharyngitisScarlet fever

    Rheumatic fever

    Impetigoanderysipelas

    Puerperal fever

    Necrotizingfasciitis

    Penicillin G

    Macrolide, e.g.clarithromycinorazithromycininpenicillin allergy

    Drainage anddebridementforNecrotizingfasciitis

    No vaccine

    Rapid antibiotictreatment helpspreventrheumatic fever

    Culture on sheep

    blood agarforming small,opalescentsurrounded bylarge zone of -hemolysis

    Serology forASO

    Very bacitracin-

    sensitiveVibrio cholerae Contaminated

    water and food,especially rawseafood

    Cholera Fluid andelectrolytereplacement

    e.g. doxycyclineto shortenduration

    Preventing fecalcontamination ofwater suppliesand food

    Adequate foodpreparation

    Culture on bloodor MacConkeyagar, enhancedby TCBS

    Positive oxidasetest

    http://en.wikipedia.org/wiki/Transmission_(medicine)http://en.wikipedia.org/wiki/Laboratory_diagnosis_of_bacteriahttp://en.wikipedia.org/wiki/Laboratory_diagnosis_of_bacteriahttp://en.wikipedia.org/wiki/Streptococcus_pyogeneshttp://en.wikipedia.org/wiki/Streptococcus_pyogeneshttp://en.wikipedia.org/wiki/Impetigohttp://en.wikipedia.org/wiki/Streptococcal_pharyngitishttp://en.wikipedia.org/wiki/Streptococcal_pharyngitishttp://en.wikipedia.org/wiki/Scarlet_feverhttp://en.wikipedia.org/wiki/Rheumatic_feverhttp://en.wikipedia.org/wiki/Impetigohttp://en.wikipedia.org/wiki/Erysipelashttp://en.wikipedia.org/wiki/Puerperal_feverhttp://en.wikipedia.org/wiki/Necrotizing_fasciitishttp://en.wikipedia.org/wiki/Necrotizing_fasciitishttp://en.wikipedia.org/wiki/Penicillin_Ghttp://en.wikipedia.org/wiki/Macrolidehttp://en.wikipedia.org/wiki/Clarithromycinhttp://en.wikipedia.org/wiki/Azithromycinhttp://en.wikipedia.org/wiki/Debridementhttp://en.wikipedia.org/w/index.php?title=Sheep_blood_agar&action=edit&redlink=1http://en.wikipedia.org/w/index.php?title=Sheep_blood_agar&action=edit&redlink=1http://en.wikipedia.org/wiki/Opalescencehttp://en.wikipedia.org/wiki/Hemolysis_(microbiology)http://en.wikipedia.org/wiki/Hemolysis_(microbiology)http://en.wikipedia.org/wiki/Hemolysis_(microbiology)http://en.wikipedia.org/wiki/Anti-streptolysin_Ohttp://en.wikipedia.org/wiki/Bacitracinhttp://en.wikipedia.org/wiki/Vibrio_choleraehttp://en.wikipedia.org/wiki/Cholerahttp://en.wikipedia.org/wiki/Doxycyclinehttp://en.wikipedia.org/wiki/Blood_agarhttp://en.wikipedia.org/wiki/MacConkey_agarhttp://en.wikipedia.org/wiki/MacConkey_agarhttp://en.wikipedia.org/wiki/Thiosulfate_citrate_bile_sucrosehttp://en.wikipedia.org/wiki/Oxidase_testhttp://en.wikipedia.org/wiki/Oxidase_testhttp://en.wikipedia.org/wiki/Oxidase_testhttp://en.wikipedia.org/wiki/Oxidase_testhttp://en.wikipedia.org/wiki/Thiosulfate_citrate_bile_sucrosehttp://en.wikipedia.org/wiki/MacConkey_agarhttp://en.wikipedia.org/wiki/MacConkey_agarhttp://en.wikipedia.org/wiki/Blood_agarhttp://en.wikipedia.org/wiki/Doxycyclinehttp://en.wikipedia.org/wiki/Cholerahttp://en.wikipedia.org/wiki/Vibrio_choleraehttp://en.wikipedia.org/wiki/Bacitracinhttp://en.wikipedia.org/wiki/Anti-streptolysin_Ohttp://en.wikipedia.org/wiki/Hemolysis_(microbiology)http://en.wikipedia.org/wiki/Hemolysis_(microbiology)http://en.wikipedia.org/wiki/Hemolysis_(microbiology)http://en.wikipedia.org/wiki/Opalescencehttp://en.wikipedia.org/w/index.php?title=Sheep_blood_agar&action=edit&redlink=1http://en.wikipedia.org/w/index.php?title=Sheep_blood_agar&action=edit&redlink=1http://en.wikipedia.org/wiki/Debridementhttp://en.wikipedia.org/wiki/Azithromycinhttp://en.wikipedia.org/wiki/Clarithromycinhttp://en.wikipedia.org/wiki/Macrolidehttp://en.wikipedia.org/wiki/Penicillin_Ghttp://en.wikipedia.org/wiki/Necrotizing_fasciitishttp://en.wikipedia.org/wiki/Necrotizing_fasciitishttp://en.wikipedia.org/wiki/Puerperal_feverhttp://en.wikipedia.org/wiki/Erysipelashttp://en.wikipedia.org/wiki/Impetigohttp://en.wikipedia.org/wiki/Rheumatic_feverhttp://en.wikipedia.org/wiki/Scarlet_feverhttp://en.wikipedia.org/wiki/Streptococcal_pharyngitishttp://en.wikipedia.org/wiki/Streptococcal_pharyngitishttp://en.wikipedia.org/wiki/Impetigohttp://en.wikipedia.org/wiki/Streptococcus_pyogeneshttp://en.wikipedia.org/wiki/Streptococcus_pyogeneshttp://en.wikipedia.org/wiki/Laboratory_diagnosis_of_bacteriahttp://en.wikipedia.org/wiki/Laboratory_diagnosis_of_bacteriahttp://en.wikipedia.org/wiki/Transmission_(medicine)
  • 8/12/2019 Classification of Infectious Disease

    32/64

    Species of human pathogenic bacteria

    Species Transmission Diseases Treatment Prevention laboratorydiagnosis

    Yersinia pestis Fleasfromanimals

    Ingestion ofanimal tissues

    Respiratorydroplets

    Plague:

    Bubonic plague

    Pneumonicplague

    Streptomycinprimarily

    Gentamicin

    Tetracyclin

    Supportivetherapy for shock

    Formalin-killedplague vaccine

    Minimizeexposure torodents and fleas

    Gram-negativesmear

    If pneumonic,culture fromaspirate onMacConkeyorblood agar

    http://en.wikipedia.org/wiki/Transmission_(medicine)http://en.wikipedia.org/wiki/Laboratory_diagnosis_of_bacteriahttp://en.wikipedia.org/wiki/Laboratory_diagnosis_of_bacteriahttp://en.wikipedia.org/wiki/Yersinia_pestishttp://en.wikipedia.org/wiki/Fleashttp://en.wikipedia.org/wiki/Plague_(disease)http://en.wikipedia.org/wiki/Bubonic_plaguehttp://en.wikipedia.org/wiki/Pneumonic_plaguehttp://en.wikipedia.org/wiki/Pneumonic_plaguehttp://en.wikipedia.org/wiki/Streptomycinhttp://en.wikipedia.org/wiki/Gentamicinhttp://en.wikipedia.org/wiki/Tetracyclinhttp://en.wikipedia.org/wiki/Shock_(circulatory)http://en.wikipedia.org/wiki/Plague_vaccinehttp://en.wikipedia.org/wiki/MacConkey_agarhttp://en.wikipedia.org/wiki/Blood_agarhttp://en.wikipedia.org/wiki/Blood_agarhttp://en.wikipedia.org/wiki/MacConkey_agarhttp://en.wikipedia.org/wiki/Plague_vaccinehttp://en.wikipedia.org/wiki/Shock_(circulatory)http://en.wikipedia.org/wiki/Tetracyclinhttp://en.wikipedia.org/wiki/Gentamicinhttp://en.wikipedia.org/wiki/Streptomycinhttp://en.wikipedia.org/wiki/Pneumonic_plaguehttp://en.wikipedia.org/wiki/Pneumonic_plaguehttp://en.wikipedia.org/wiki/Bubonic_plaguehttp://en.wikipedia.org/wiki/Plague_(disease)http://en.wikipedia.org/wiki/Fleashttp://en.wikipedia.org/wiki/Yersinia_pestishttp://en.wikipedia.org/wiki/Laboratory_diagnosis_of_bacteriahttp://en.wikipedia.org/wiki/Laboratory_diagnosis_of_bacteriahttp://en.wikipedia.org/wiki/Transmission_(medicine)
  • 8/12/2019 Classification of Infectious Disease

    33/64

    Comparison table of clinically important virus families and species

    Family Baltimoregroup

    Important species envelopment Virion shape Replicationsite

    Adenoviridae dsDNA adenovirus non-enveloped icosahedral nucleus

    Picornaviridae +ssRNA coxsackievirus, hepatitis Avirus, poliovirus, rhinovirus

    non-enveloped icosahedral

    Herpesviridae dsDNA Herpes simplex, type 1,Herpes simplex, type 2,

    Varicella-zoster virus,

    Epstein-barr virus, Humancytomegalovirus, Humanherpesvirus, type 8

    enveloped nucleus

    Hepadnaviridae dsDNAandssDNA

    Hepatitis B virus enveloped icosahedral nucleus

    Flaviviridae +ssRNA Hepatitis C virus, yellowfever virus, dengue virus,

    West Nile virus

    enveloped icosahedral

    Retroviridae +ssRNA Human immunodeficiencyvirus(HIV)

    enveloped

    http://en.wikipedia.org/wiki/Baltimore_classificationhttp://en.wikipedia.org/wiki/Baltimore_classificationhttp://en.wikipedia.org/wiki/Viral_envelopehttp://en.wikipedia.org/wiki/Adenoviridaehttp://en.wikipedia.org/wiki/DsDNA_virushttp://en.wikipedia.org/wiki/Picornaviridaehttp://en.wikipedia.org/wiki/Positive-sense_ssRNA_virushttp://en.wikipedia.org/wiki/Coxsackievirushttp://en.wikipedia.org/wiki/Hepatitis_A_virushttp://en.wikipedia.org/wiki/Hepatitis_A_virushttp://en.wikipedia.org/wiki/Poliovirushttp://en.wikipedia.org/wiki/Rhinovirushttp://en.wikipedia.org/wiki/Herpesviridaehttp://en.wikipedia.org/wiki/DsDNA_virushttp://en.wikipedia.org/wiki/Herpes_simplex,_type_1http://en.wikipedia.org/wiki/Herpes_simplex,_type_2http://en.wikipedia.org/wiki/Varicella-zoster_virushttp://en.wikipedia.org/wiki/Epstein-barr_virushttp://en.wikipedia.org/wiki/Human_cytomegalovirushttp://en.wikipedia.org/wiki/Human_cytomegalovirushttp://en.wikipedia.org/wiki/Human_herpesvirus,_type_8http://en.wikipedia.org/wiki/Human_herpesvirus,_type_8http://en.wikipedia.org/wiki/Hepadnaviridaehttp://en.wikipedia.org/wiki/DsDNA_virushttp://en.wikipedia.org/wiki/SsDNA_virushttp://en.wikipedia.org/wiki/Hepatitis_B_virushttp://en.wikipedia.org/wiki/Flaviviridaehttp://en.wikipedia.org/wiki/Positive-sense_ssRNA_virushttp://en.wikipedia.org/wiki/Hepatitis_C_virushttp://en.wikipedia.org/wiki/Yellow_feverhttp://en.wikipedia.org/wiki/Yellow_feverhttp://en.wikipedia.org/wiki/Dengue_feverhttp://en.wikipedia.org/wiki/West_Nile_virushttp://en.wikipedia.org/wiki/Retroviridaehttp://en.wikipedia.org/wiki/Positive-sense_ssRNA_virushttp://en.wikipedia.org/wiki/Human_immunodeficiency_virushttp://en.wikipedia.org/wiki/Human_immunodeficiency_virushttp://en.wikipedia.org/wiki/Human_immunodeficiency_virushttp://en.wikipedia.org/wiki/Human_immunodeficiency_virushttp://en.wikipedia.org/wiki/Positive-sense_ssRNA_virushttp://en.wikipedia.org/wiki/Retroviridaehttp://en.wikipedia.org/wiki/West_Nile_virushttp://en.wikipedia.org/wiki/Dengue_feverhttp://en.wikipedia.org/wiki/Yellow_feverhttp://en.wikipedia.org/wiki/Yellow_feverhttp://en.wikipedia.org/wiki/Hepatitis_C_virushttp://en.wikipedia.org/wiki/Positive-sense_ssRNA_virushttp://en.wikipedia.org/wiki/Flaviviridaehttp://en.wikipedia.org/wiki/Hepatitis_B_virushttp://en.wikipedia.org/wiki/SsDNA_virushttp://en.wikipedia.org/wiki/DsDNA_virushttp://en.wikipedia.org/wiki/Hepadnaviridaehttp://en.wikipedia.org/wiki/Human_herpesvirus,_type_8http://en.wikipedia.org/wiki/Human_herpesvirus,_type_8http://en.wikipedia.org/wiki/Human_cytomegalovirushttp://en.wikipedia.org/wiki/Human_cytomegalovirushttp://en.wikipedia.org/wiki/Epstein-barr_virushttp://en.wikipedia.org/wiki/Epstein-barr_virushttp://en.wikipedia.org/wiki/Epstein-barr_virushttp://en.wikipedia.org/wiki/Varicella-zoster_virushttp://en.wikipedia.org/wiki/Varicella-zoster_virushttp://en.wikipedia.org/wiki/Varicella-zoster_virushttp://en.wikipedia.org/wiki/Herpes_simplex,_type_2http://en.wikipedia.org/wiki/Herpes_simplex,_type_1http://en.wikipedia.org/wiki/DsDNA_virushttp://en.wikipedia.org/wiki/Herpesviridaehttp://en.wikipedia.org/wiki/Rhinovirushttp://en.wikipedia.org/wiki/Poliovirushttp://en.wikipedia.org/wiki/Hepatitis_A_virushttp://en.wikipedia.org/wiki/Hepatitis_A_virushttp://en.wikipedia.org/wiki/Coxsackievirushttp://en.wikipedia.org/wiki/Positive-sense_ssRNA_virushttp://en.wikipedia.org/wiki/Picornaviridaehttp://en.wikipedia.org/wiki/DsDNA_virushttp://en.wikipedia.org/wiki/Adenoviridaehttp://en.wikipedia.org/wiki/Viral_envelopehttp://en.wikipedia.org/wiki/Baltimore_classificationhttp://en.wikipedia.org/wiki/Baltimore_classification
  • 8/12/2019 Classification of Infectious Disease

    34/64

    Comparison table of clinically important virus families and species

    Family Baltimoregroup

    Important species envelopment Virion shape Replicationsite

    Orthomyxoviridae -ssRNA Influenza virus enveloped spherical nucleus

    Paramyxoviridae -ssRNA Measles virus, Mumps virus,Parainfluenza virus,Respiratory syncytial virus,Human metapneumovirus

    enveloped spherical

    Papillomaviridae dsDNA Human papillomavirus non-enveloped icosahedral nucleus

    Rhabdoviridae -ssRNA Rabies virus enveloped helical, bulletshaped

    Togaviridae +ssRNA Rubella virus enveloped icosahedral

    Parvoviridae ssDNA Human bocavirus, ParvovirusB19

    enveloped icosahedral

    http://en.wikipedia.org/wiki/Baltimore_classificationhttp://en.wikipedia.org/wiki/Baltimore_classificationhttp://en.wikipedia.org/wiki/Viral_envelopehttp://en.wikipedia.org/wiki/Orthomyxoviridaehttp://en.wikipedia.org/wiki/Negative-sense_ssRNA_virushttp://en.wikipedia.org/wiki/Influenza_virushttp://en.wikipedia.org/wiki/Paramyxoviridaehttp://en.wikipedia.org/wiki/Negative-sense_ssRNA_virushttp://en.wikipedia.org/wiki/Measles_virushttp://en.wikipedia.org/wiki/Mumps_virushttp://en.wikipedia.org/wiki/Parainfluenza_virushttp://en.wikipedia.org/wiki/Respiratory_syncytial_virushttp://en.wikipedia.org/wiki/Human_metapneumovirushttp://en.wikipedia.org/wiki/Papillomaviridaehttp://en.wikipedia.org/wiki/DsDNA_virushttp://en.wikipedia.org/wiki/Human_papillomavirushttp://en.wikipedia.org/wiki/Rhabdoviridaehttp://en.wikipedia.org/wiki/Negative-sense_ssRNA_virushttp://en.wikipedia.org/wiki/Rabies_virushttp://en.wikipedia.org/wiki/Togaviridaehttp://en.wikipedia.org/wiki/Positive-sense_ssRNA_virushttp://en.wikipedia.org/wiki/Rubella_virushttp://en.wikipedia.org/wiki/Parvoviridaehttp://en.wikipedia.org/wiki/SDNA_virushttp://en.wikipedia.org/wiki/Human_bocavirushttp://en.wikipedia.org/wiki/Parvovirus_B19http://en.wikipedia.org/wiki/Parvovirus_B19http://en.wikipedia.org/wiki/Parvovirus_B19http://en.wikipedia.org/wiki/Parvovirus_B19http://en.wikipedia.org/wiki/Human_bocavirushttp://en.wikipedia.org/wiki/SDNA_virushttp://en.wikipedia.org/wiki/Parvoviridaehttp://en.wikipedia.org/wiki/Rubella_virushttp://en.wikipedia.org/wiki/Positive-sense_ssRNA_virushttp://en.wikipedia.org/wiki/Togaviridaehttp://en.wikipedia.org/wiki/Rabies_virushttp://en.wikipedia.org/wiki/Negative-sense_ssRNA_virushttp://en.wikipedia.org/wiki/Negative-sense_ssRNA_virushttp://en.wikipedia.org/wiki/Rhabdoviridaehttp://en.wikipedia.org/wiki/Human_papillomavirushttp://en.wikipedia.org/wiki/DsDNA_virushttp://en.wikipedia.org/wiki/Papillomaviridaehttp://en.wikipedia.org/wiki/Human_metapneumovirushttp://en.wikipedia.org/wiki/Respiratory_syncytial_virushttp://en.wikipedia.org/wiki/Parainfluenza_virushttp://en.wikipedia.org/wiki/Mumps_virushttp://en.wikipedia.org/wiki/Measles_virushttp://en.wikipedia.org/wiki/Negative-sense_ssRNA_virushttp://en.wikipedia.org/wiki/Negative-sense_ssRNA_virushttp://en.wikipedia.org/wiki/Paramyxoviridaehttp://en.wikipedia.org/wiki/Influenza_virushttp://en.wikipedia.org/wiki/Negative-sense_ssRNA_virushttp://en.wikipedia.org/wiki/Negative-sense_ssRNA_virushttp://en.wikipedia.org/wiki/Orthomyxoviridaehttp://en.wikipedia.org/wiki/Viral_envelopehttp://en.wikipedia.org/wiki/Baltimore_classificationhttp://en.wikipedia.org/wiki/Baltimore_classification
  • 8/12/2019 Classification of Infectious Disease

    35/64

    The clinical characteristics of viruses may differ

    substantially among species within the same family:

    Type Family Transmission Diseases Treatment Prevention laboratorydiagnosis

    adenovirus adenoviridae droplet contact(mainly)

    fecal-oral

    venereal

    direct contact(ocularinfections)

    acute febrilepharyngitis

    pharyngoconjunctivalfever

    epidemickeratoconjunctivitis

    infantilegastroenteritis

    None None virusneutralization

    hemagglutinationassay

    ELISA

    Coxsackievirus Picornaviridae fecal-oral,droplet contact

    Coxsackie infections None None Cell culture,antibodydetection

    http://en.wikipedia.org/wiki/Transmission_(medicine)http://en.wikipedia.org/wiki/Laboratory_diagnosis_of_virushttp://en.wikipedia.org/wiki/Laboratory_diagnosis_of_virushttp://en.wikipedia.org/wiki/Adenoviridaehttp://en.wikipedia.org/w/index.php?title=Acute_febrile_pharyngitis&action=edit&redlink=1http://en.wikipedia.org/w/index.php?title=Acute_febrile_pharyngitis&action=edit&redlink=1http://en.wikipedia.org/wiki/Pharyngoconjunctival_feverhttp://en.wikipedia.org/wiki/Pharyngoconjunctival_feverhttp://en.wikipedia.org/w/index.php?title=Epidemic_keratoconjunctivitis&action=edit&redlink=1http://en.wikipedia.org/w/index.php?title=Epidemic_keratoconjunctivitis&action=edit&redlink=1http://en.wikipedia.org/w/index.php?title=Infantile_gastroenteritis&action=edit&redlink=1http://en.wikipedia.org/w/index.php?title=Infantile_gastroenteritis&action=edit&redlink=1http://en.wikipedia.org/w/index.php?title=Virus_neutralization&action=edit&redlink=1http://en.wikipedia.org/w/index.php?title=Virus_neutralization&action=edit&redlink=1http://en.wikipedia.org/wiki/Hemagglutination_assayhttp://en.wikipedia.org/wiki/Hemagglutination_assayhttp://en.wikipedia.org/wiki/ELISAhttp://en.wikipedia.org/wiki/Coxsackievirushttp://en.wikipedia.org/wiki/Picornaviridaehttp://en.wikipedia.org/w/index.php?title=Coxsackie_infections&action=edit&redlink=1http://en.wikipedia.org/w/index.php?title=Coxsackie_infections&action=edit&redlink=1http://en.wikipedia.org/wiki/Picornaviridaehttp://en.wikipedia.org/wiki/Coxsackievirushttp://en.wikipedia.org/wiki/ELISAhttp://en.wikipedia.org/wiki/ELISAhttp://en.wikipedia.org/wiki/Hemagglutination_assayhttp://en.wikipedia.org/wiki/Hemagglutination_assayhttp://en.wikipedia.org/wiki/Hemagglutination_assayhttp://en.wikipedia.org/w/index.php?title=Virus_neutralization&action=edit&redlink=1http://en.wikipedia.org/w/index.php?title=Virus_neutralization&action=edit&redlink=1http://en.wikipedia.org/w/index.php?title=Infantile_gastroenteritis&action=edit&redlink=1http://en.wikipedia.org/w/index.php?title=Infantile_gastroenteritis&action=edit&redlink=1http://en.wikipedia.org/w/index.php?title=Infantile_gastroenteritis&action=edit&redlink=1http://en.wikipedia.org/w/index.php?title=Epidemic_keratoconjunctivitis&action=edit&redlink=1http://en.wikipedia.org/w/index.php?title=Epidemic_keratoconjunctivitis&action=edit&redlink=1http://en.wikipedia.org/w/index.php?title=Epidemic_keratoconjunctivitis&action=edit&redlink=1http://en.wikipedia.org/wiki/Pharyngoconjunctival_feverhttp://en.wikipedia.org/wiki/Pharyngoconjunctival_feverhttp://en.wikipedia.org/wiki/Pharyngoconjunctival_feverhttp://en.wikipedia.org/w/index.php?title=Acute_febrile_pharyngitis&action=edit&redlink=1http://en.wikipedia.org/w/index.php?title=Acute_febrile_pharyngitis&action=edit&redlink=1http://en.wikipedia.org/wiki/Adenoviridaehttp://en.wikipedia.org/wiki/Laboratory_diagnosis_of_virushttp://en.wikipedia.org/wiki/Laboratory_diagnosis_of_virushttp://en.wikipedia.org/wiki/Transmission_(medicine)
  • 8/12/2019 Classification of Infectious Disease

    36/64

  • 8/12/2019 Classification of Infectious Disease

    37/64

    The clinical characteristi