cheminform abstract: regio- and stereoselective synthesis of isoxazolines via cycloaddition...

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2002 diastereoselective syntheses, enantioselective syntheses diastereoselective syntheses, enantioselective syntheses (incl. cis/trans-isomerism) O 0031 37 - 030 Regio- and Stereoselective Synthesis of Isoxazolines via Cycloaddition Reactions Using Pregnenolone as Chiral Auxiliary. Asymmetric 1,3-dipolar cycloaddition reaction of nitrile oxides (II) to olefins (I) is achieved using pregnenolone as chiral auxiliary. This is the first example for the use of steroidal chiral auxiliaries in asymmetric synthesis. — (SHARMA, UTPAL; BORA, UTPAL; CHETIA, APURBA; BORUAH, ROMESH C.; SANDHU, JAGIR SINGH; Indian J. Chem., Sect. B: Org. Chem. Incl. Med. Chem. 41 (2002) 5, 1012-1014; Org. Chem. Div., Reg. Res. Lab., Jorhat 785 006, India; EN) 1

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Page 1: ChemInform Abstract: Regio- and Stereoselective Synthesis of Isoxazolines via Cycloaddition Reactions Using Pregnenolone as Chiral Auxiliary

2002 diastereoselective syntheses, enantioselective syntheses

diastereoselective syntheses, enantioselective syntheses (incl. cis/trans-isomerism)O 0031

37 - 030Regio- and Stereoselective Synthesis of Isoxazolines via CycloadditionReactions Using Pregnenolone as Chiral Auxiliary. — Asymmetric1,3-dipolar cycloaddition reaction of nitrile oxides (II) to olefins (I) is achievedusing pregnenolone as chiral auxiliary. This is the first example for the use ofsteroidal chiral auxiliaries in asymmetric synthesis. — (SHARMA, UTPAL;BORA, UTPAL; CHETIA, APURBA; BORUAH, ROMESH C.; SANDHU,JAGIR SINGH; Indian J. Chem., Sect. B: Org. Chem. Incl. Med. Chem. 41(2002) 5, 1012-1014; Org. Chem. Div., Reg. Res. Lab., Jorhat 785 006, India;EN)

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