cheminform abstract: 1-alkyl-2,4-dihydro-1h-pyrazino[2,1-b]quinazoline-3,6-diones as glycine...

2002 pyrazine derivatives pyrazine derivatives R 0550 34 - 173 1-Alkyl-2,4-dihydro-1H-pyrazino[2,1-b]quinazoline-3,6-diones as Glycine Templates. Synthesis of Fiscalin B. — The regioselective alkylation of the title compounds (I) and (V) proceeds diastereoselectively in the case of (V). Product (IIIe) can be used for the preparation of ﬁscalin B. — (HERNANDEZ, FERNANDO; BUENADICHA, FELIX L.; AVENDANO, CARMEN; SOELLHUBER, MONICA; Tetrahedron: Asymmetry 12 (2001) 24, 3387-3398; Dep. Quim. Org. Farm., Fac. Farm., Univ. Complutense, E-28040 Madrid, Spain; EN) 1

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Page 1: ChemInform Abstract: 1-Alkyl-2,4-dihydro-1H-pyrazino[2,1-b]quinazoline-3,6-diones as Glycine Templates. Synthesis of Fiscalin B

2002 pyrazine derivatives

pyrazine derivativesR 0550

34 - 1731-Alkyl-2,4-dihydro-1H-pyrazino[2,1-b]quinazoline-3,6-diones asGlycine Templates. Synthesis of Fiscalin B. — The regioselectivealkylation of the title compounds (I) and (V) proceeds diastereoselectively inthe case of (V). Product (IIIe) can be used for the preparation of fiscalin B.— (HERNANDEZ, FERNANDO; BUENADICHA, FELIX L.; AVENDANO,CARMEN; SOELLHUBER, MONICA; Tetrahedron: Asymmetry 12 (2001) 24,3387-3398; Dep. Quim. Org. Farm., Fac. Farm., Univ. Complutense, E-28040Madrid, Spain; EN)

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