charotar university of science and …. pharm. semester – ii syllabus charusat faculty of pharmacy...
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CHAROTAR UNIVERSITY
OF SCIENCE AND TECHNOLOGY
FACULTY OF PHARMACY
Syllabus for 2nd Semester B. Pharm. Programme
B. Pharm. Semester – II Syllabus CHARUSAT
FACULTY OF PHARMACY 2
Human Anatomy & Physiology – II (PH 106)
(Theory and Practical)
Credits: 3 (Theory) Contact Hours per week: 3 (Theory)
: 1.5 (Practical) : 3 (Practical)
Objective of the Course:
To make students familiar with the principles of human anatomy and physiology as well as basic
concepts related to health.
Student Learning Outcomes/Objectives:
At the end of the course, the student will be able to understand the concept of anatomy and
physiology of different organ systems which is a prerequisite for understanding the concepts of
pharmacology.
Instructional Methods and Pedagogy:
Faculty member/s shall explain in a class room using black board and multimedia projector,
charts and models of different organ systems.
Outline of the Course:
No. Unit Minimum No.
of Contact Hours
Approx.
weightage %
1 Haemopoetic system 6 15 %
2 Cardiovascular system 12 20 %
3 Respiratory system 5 10 %
4 Urinary system 4 15 %
5 Lymph and lymphatic system 3 5 %
6 Body defense Mechanisms & Immunity 4 10 %
7 Digestive system 4 10 %
8 Water & electrolyte balance 3 5 %
B. Pharm. Semester – II Syllabus CHARUSAT
FACULTY OF PHARMACY 3
9 Vitamins, Nutrition & Metabolism 2 5 %
10 Basic concept on Genetic Disorders 2 5 %
Total 45 100 %
Detailed Syllabus (Theory):
No. Unit details Contact
Hours
1 Haemopoetic system:
- Composition and function of blood and its elements.
- Their disorders, blood group and their significance.
- Mechanism of coagulation, disorder of platelets and coagulation.
6
2 Cardiovascular system:
- Basic anatomy of heart, blood vessels and circulation.
- Basic understanding of cardiac cycle, heart sounds and
electrocardiogram.
- Blood pressure and its regulation.
- Brief outline of cardiovascular disorders like hypertension,
hypotension, arteriosclerosis, angina, myocardial infarction,
congestive cardiac failure and cardiac arrhythmias.
12
3 Respiratory system:
- Anatomy of respiratory organ, function of respiration,
mechanism and regulation of respiration, respiratory volumes and
vital capacity.
5
4 Urinary system:
- Various parts, structure and function of the kidney and
urinary tract. Physiology of urine formation and acid- base
balance. Disorders of urinary system.
4
5 Lymph and lymphatic system:
- Composition, formulation and circulation of lymph, disorder of lymph
and lymphatic system. Basic physiology and function of spleen.
3
6 Body defense Mechanisms & Immunity: 4
B. Pharm. Semester – II Syllabus CHARUSAT
FACULTY OF PHARMACY 4
Detailed Syllabus (Practical):
No. Aim of the Practical
1 Use & care of Microscope.
2 To find out total W.B.C Count of human blood.
3 To find out Differential W.B.C count of human blood.
4 To find out total R.B.C Count of human blood.
4 To find out Haemoglobin content, oxygen carrying capacity & colour index of human blood.
5 To find out effect of osmotic pressure on R.B.C of human blood.
6 To find out bleeding and clotting time of human blood.
- Basic principles of immunity, innate immunity, adaptive
immunity, immune interactions, immunotherapy, acquired
immunity and brief overview of immune system pathology.
7 Digestive system:
- Gross anatomy of Gastro Intestinal Tract, Functions of its different
parts including those of liver, pancreas and gall bladder, various
Gastro Intestinal Tracts and their role in absorption and digestion of
food. Disorders of digestive system.
4
8 Water & electrolyte balance:
- Brief overview of body fluids & regulation of intracellular fluid
composition, extracellular fluid composition, ion concentrations, water
content balance.
3
9 Vitamins, Nutrition & Metabolism:
- Brief overview of different Vitamins.
- Concept of Body Nutrition, metabolism of carbohydrates, lipid &
proteins, metabolic rate.
2
10 Basic concept on Genetic Disorders:
- Introduction to DNA, Chromosomes, Gene mutation
- Application of genetics in pharmacy
Genetic disorders related to different body system & organs
2
B. Pharm. Semester – II Syllabus CHARUSAT
FACULTY OF PHARMACY 5
7 To Study the effect of Posture on Vital Capacity using Spiro meter.
8 To perform biochemical Analysis of Urine.
(To find out normal & abnormal Constituents of given urine sample.)
9 To perform biochemical Analysis of Urine.
(To find out normal & abnormal Constituents of human urine sample.)
10 Determination of pulse rate, blood pressure, listening to heart sounds with the help of
Sphygmomanometer and Stethoscope.
11 To record electrocardiogram (ECG) of a person.
12 To find out urine glucose estimation by use of urine glucose strip ( DIASTIX)
13 To study following systems using charts and models: Cardiovascular system Respiratory system,
Urinary system, Digestive system.
14 To study histology of different tissues using permanent slides.
Recommended study materials:
1. Fundamentals of anatomy and physiology; Martini F; Prentice hall; 2nd Ed. 1992.
2. Anatomy and physiology; Seeley R R, Stephens T D and Tate P Mosby, St Louis; 3rd Ed.;
1995.
3. Text book of medical physiology; Guyton; W. B. Saunders Co.; Philadelphiea; 8th Ed.
1991.
4. West J. B. Best and Taylor’s physiological basis of medical practice; Williams and Wilkins,
Baltimone; 12th Ed.1989.
5. Principles of anatomy and physiology; Tortora G. J. and Anagnodokos, N. P.; Harper and
Colling Publishers, New York; 7th Ed. 1992.
6. Human anatomy, physiology and health education; Gandhi, T. P.; B. S. Shah Prakashan,
Ahmedabad; 9th Ed. 1998.
7. Preparatory Manual for undergraduates’ physiology; Joshi, Vijaya D.; B. I. Churchill
Livingstone; 1995.
8. Human physiology; Chatteerjee, C. C.; Medical Allied Agency Calcutta; 10th Ed.1985.
9. Physiology and anatomy; Clancy, John and MoVicet, A. J.; Edward Arnold; 1995.
B. Pharm. Semester – II Syllabus CHARUSAT
FACULTY OF PHARMACY 6
10. Human Physiology; Subhash Shalya; C. B. S. Publishers New Delhi; 1st Ed. 1994.
11. Human Anatomy; Chaurasia, B.O; C. B. S. Publishers New Delhi; 3rd Ed. 1994
12. Anatomy and physiology in health and illness; Ross and Wilson’s; Churchill Livingstone;
8th Ed. 1995.
13. Health Education and Community Pharmacy; Parmar N. S; C. B. S. Publishers New Delhi
1995.
14. Practical anatomy Physiology and biochemistry; Goyal R. K.; B. S. Shah Prakashan,
Ahemedabad; 1994.
15. A textbook of history; Garg K. et. al; C. B. S. Publishers, New Delhi; 2nd Ed.1991.
16. Text books of histology; Lesson C. R. et. al.; W. B. Saunders Co.5th Ed.
17. Atlas of anatomy; Aqur, Anne M.R.; Williams and Wilkins 9th Ed.1991.
18. A photographic atlas for the anatomy and physiology lab.; Van de Graaff and Crewley, J.
L.; Mortan Publishing Co.; 3rd Ed. 1991.
19. A text book of practical physiology; Ghai, C. L.; Jaypee Brothers Medical Publishers (P)
Ltd.;4th Ed. 1998.(Practical).
20. Microbiology- An Introduction; Tortora Gerard J; Pearson Edu Asia; 2004.
B. Pharm. Semester – II Syllabus CHARUSAT
FACULTY OF PHARMACY 7
Basic Pharmacognosy – II (PH 107)
(Theory & Practical)
Credits: 3 (Theory) Contact Hours per week: 3 (Theory)
: 1.5 (Practical) : 3 (Practical)
Objective of the Course:
The objective of the course is to provide the knowledge about probable types of adulteration,
their detection in herbal drug samples. Phytochemical and Pharmacognostic features of
carbohydrate and lipid containing drugs and types of pharmaceutical aids will be discussed.
The students are introduced to the types of phytoconstituents, their physico chemical
properties and the methods of their detection.
Student Learning Outcomes/Objectives:
At the end of the course, the student are expected to
understand different types of adulteration of crude drugs
understand different evaluation methods ascertain the presence or absence of
adulteration
recognize the crude drugs mentioned in the course
learn the pharmacognostic aspects specifically, the sources, the preparation methods
and utilization of those substances obtained from the natural sources.
learn different classes of phytoconstituents along with their exact definition and physico
chemical properties and the preliminary chemical tests to detect those from plants/
plant extracts.
Instructional Methods and Pedagogy:
The lectures will be delivered using
Black board
Over Head Projector
B. Pharm. Semester – II Syllabus CHARUSAT
FACULTY OF PHARMACY 8
Multimedia projector
Visit of herbal garden
4. Outline of the Course (Theory):
No. Unit Minimum No.
of Contact Hours
Approx.
weightage %
1 Quality control of crude drugs. 11 35 %
2 Introduction to the active phytoconstituents. 5 15 %
3 Systematic Pharmacognostic study of the crude
drugs.
17 30 %
4 Study of pharmaceutical aids. 7 10 %
5 Study of fibers used in pharmacy. 5 10 %
Total 45 100 %
Detailed Syllabus (Theory):
No. Unit details Contact
Hours
1 Quality control of crude drugs:
Adulteration of crude drugs and their detection by organoleptic, microscopic, physical,
chemical, biological and other physical and chemical methods of evaluation.
11
2 Introduction to the active phytoconstituents:
Introduction to the active constituents of the drugs and their physico-chemical
properties.
5
3 Systamatic and Pharmacognostic study of the crude drugs:
(A) Carbohydrates and derived products: Agar, Guargum, Acacia, Honey, Isabgol,
Pectin, Starch, Sterculia, Tragacath and Sodium alginate.
(B) Lipids: Beeswax, Olive Oil, Castor oil, Cocoa butter, Cod liver oil, sesame oil, wool
fat, Linseed oil, Shark liver oil.
17
4 Study of pharmaceutical aids like talc, diatomite, kaolin, bentonite, gelatin, and
natural colors.
7
5 Study of fibers used in pharmacy such as cotton, silk, wool, nylon, glass wool, 5
B. Pharm. Semester – II Syllabus CHARUSAT
FACULTY OF PHARMACY 9
polyester and asbestos.
Outline of the Course (Practical):
1 Microscopic measurement and identification of cell and cell content: Starch grains, Mineral crystals
and phloem fibers.
2 Study of different types of stomata and trichomes using microscopic method.
3 Determination of leaf constants such as stomatal index, vein-islet numbers, vein- termination
number and palisade ratio.
3 Evaluation of naturally occurring oils and fats by determining analytical constants like acid value,
Saponification value, iodine value, peroxide value and refractive index.
4 Identification of crude drugs belonging to Carbohydrates and Lipids.
5 Study of fibers and pharmaceutical aids.
Detailed Syllabus (Practical):
No. Aim of the Practical
1 Microscopic studies of Ergastic Contents present in the plant cell.
2 Microscopical study of different types of stomata in different leaf samples.
3 Microscopical study of different types of trichomes in different leaf samples.
4 Determination of Stomatal Index of leaf sample.
5 Determination of Vein islet and Vein termination number of leaf sample.
6 Determination of Palisade Ratio of leaf sample.
7 Quantitative estimation of starch grains in given sample of ginger powder by lycopodium spore
method.
8 Estimation of total fibre content in give sample of Cinchona Powder.
9 Morphology and microscopy study of Isabgol seed.
10 Morphology and microscopy study of Linseed.
11 Morphological Studies of Lipid and Carbohydrate containing Drugs.
12 Chemical Tests of Lipids and Carbohydrates.
13 Determination of Acid Value and Saponification Value of given Sample of Oil.
14 Determination of Iodine Value and Peroxide value of given Sample of Oil.
B. Pharm. Semester – II Syllabus CHARUSAT
FACULTY OF PHARMACY 10
Recommended study materials:
a) Text books:
1. Pharmacognosy; C. K. Kokate, A. P. Purohit, S. B. Gokhale; Nirali prakashan, Pune; 39th
Edition; 2007.
2. Botany for degree students; A. C. Dutta; Calcutta Oxford university press, New Delhi; 15
impressions; 1994.
3. A textbook of Pharmacognosy; Mamta Shah, Urvashi Shah, Sangita Marfatia; Nirav and
Roopal Prakashan; 2008-09.
4. Textbook of Pharmacognosy I; S. B. Dhake, Parul B. Patel; Nirav and Roopal Prakashan;
2008-09.
5. Pharmacognosy; J. S. Quadry; B. S. Shah Prakashan, Ahemedabad; 14th edition; 2008-09.
b) Reference books:
6. Pharmacognosy; V. E. Tylar, L. R. Brady, J. E. Habbers; Lea and Febgir Philadelphia; 8th
edition; 1981.
7. Pharmacognosy of powdered crude drugs; M. A. Tyenger; Manipal power press; 1st
Edition; 1974.
8. Trease and Evan’s Pharmacognosy; W. C. Evans; W. B. Saunders Co., Singapore; 15th
Edition; 2008.
9. Text Book Pharmacognosy; T.E. Wallis; CBS Publishers and Distributors, Delhi; 5th
Edition; Reprint-2005.
B. Pharm. Semester – II Syllabus CHARUSAT
FACULTY OF PHARMACY 11
Pharmaceutical Chemistry - I (Physical) (PH 108)
(Theory)
Credits: 2 Contact Hours per week: 2
Objective of the course:
The course covers fundamentals of chemistry including solutions, kinetics, equilibria,
thermodynamics, chemical catalysis, nuclear chemistry and photochemical reactions.
Students learning outcomes/objectives:
By the end of this course, the student should have a good understanding of the history
and basic concepts of physical chemistry
Students should understand principles of states of matter, aqueous solutions, acid-base
chemistry, thermodynamics, chemical catalysis and their applications.
Instructional methods and pedagogy:
Using blackboard and one-way communication from a teacher t o a student.
Using an overhead and LCD projector
Outline of the course (Theory):
No. Unit Minimum No. of
Contact Hours
Approx.
Weightage %
1 The Liquid State 04 20 %
2 Nuclear and Radiopharmaceutical Chemistry 06 10 %
3 Photochemistry 03 10 %
4 Electrolytes 05 15 %
5 Solutions 04 15 %
6 Chemical Catalysis 02 10 %
7 Thermodynamics 06 20 %
Total 30 100 %
B. Pharm. Semester – II Syllabus CHARUSAT
FACULTY OF PHARMACY 13
Detailed syllabus (Theory):
No. Unit details Contact
Hours
1 The Liquid State
Physical properties and applications of surface tension, parachor,
viscosity, refractive index, optical rotation, dipole moment of the
chemical constituents in pharmacy.
04
2 Nuclear and Radiopharmaceutical Chemistry
Structure of nucleus, methods of nuclear radiation measurement,
nuclear reaction, fusion and fission, Radiation dosimetry, Radio opaque
contrast medium, (Therapeutic and diagnostic applications of radio
pharmaceuticals). Basic principals of Radioactivity Rays, and
Measurements of Radioactivity, Applications.
06
3 Photochemistry
Consequences of lights adsorption, Jablenski diagram, Quantum
efficiency, photosensitization reactions.
03
4 Electrolytes
Extra and intracellular ions: Chlorides, Phosphate, Bicarbonate, Na, K,
Ca, Mg. Electrolytes used for replacement therapy, physiological acid
base balance.
05
5 Solutions
Ideal and real solutions, solutions of gases in liquids, colligative
properties, partition co-efficient, conductance and its measurement,
Debye-Huckel theory.
04
6 Chemical Catalysis
characteristics of homogeneous and heterogeneous catalysts, acid-base
catalysis.
02
7 Thermodynamics 06
B. Pharm. Semester – II Syllabus CHARUSAT
FACULTY OF PHARMACY 14
Basic principles, First, Second and Third laws, Zeroth Law, absolute
temperature scale, thermochemical equations, phase equilibria and
phase rule, One and two component systems.
Recommended study material:
1. Indian Pharmacopoeia; Government of India: New Delhi, 2007
2. “Medicinal and Pharmaceutical Chemistry” Inorganic; J. H. Block, E. B. Roche; Varghese
Publication; Indian edition.
3. “Text Book of Pharmaceutical Chemistry” Revised by L. M. Atherden, Bentley & Driver’s
; Oxford Medical Publications; 8th edition.
4. “Essential of Physical Chemistry”; B.S. Bhal, G.D. Tuli and Arun
Bhal, S. Chand and Company Ltd. 23rd Edition,1996.
5. “The Science and Practice of Pharmacy”; Remington, Lipincott, William and Wilkins;
20th edition.
6. “Advanced Physical Chemistry”, Gurdeep Raj, Goel Publishing House; 20th Edition,
1996.
7. “Textbook of physical chemistry” Soni P. L., Sultan Chand and Sons.
8. “Text book of Physical Chemistry”; Semuel Glasstone, Macmillan India Limited, 2nd Ed.
1995.
9. “Elements of physical Chemistry”; Peter Atkins, Julio De Paula, Oxford University Press,
4th Ed. 2007.
B. Pharm. Semester – II Syllabus CHARUSAT
FACULTY OF PHARMACY 15
Pharmaceutical Engineering – II (PH 109)
(Theory & Practical)
Credits: 3 (Theory) Contact Hours per week: 3 (Theory)
: 1.5 (Practical) : 3 (Practical)
Objective of the course:
To study basic process which are used in different stage during preparation of raw
materials in pharmaceutical industries.
Subject gives the guideline for clarification and purification of solid and liquid raw
materials.
Students learning outcomes/objectives:
By the end of this course, the student should have a good understanding of the basic
concepts of clarification and purification of solid and liquid raw materials in pharmacy.
Students should be able to know the appropriate instrumental requirement for different
types of unit operations used in pharmaceutical industry.
Instructional methods and pedagogy:
The lectures will be delivered using
Black board,
Over Head Projector
Multimedia projector
Outline of the course (Theory):
No. Unit Minimum no. of
Contact Hours.
Approx.
Weightage %
1 Filtration 08 18 %
2 Centrifugation 05 10 %
3 Evaporation 08 18 %
4 Distillation 08 18 %
B. Pharm. Semester – II Syllabus CHARUSAT
FACULTY OF PHARMACY 16
5 Drying 08 18 %
6 HVAC (Humidity Ventilation and Air Conditioning) 08 18 %
Total 45 100 %
Detailed syllabus (Theory):
No. Unit details Contact
Hours
1 Filtration: Theory and mechanism of filtration process, factors affecting rate of filtration,
filter media, filter aids, types of filters, operation of filters, industrial filters-leaf filter,
filter press, rotary filter, edge filters, cartridge filters, membrane filters, optimum
cleaning cycle in batch filters, etc. Mathematical problems on filtration.
8
2 Centrifugation: Principle and theory of centrifugation, industrial centrifuges-perforated
basket centrifuge, sedimentation type centrifuge, continuous centrifuges etc.
Applications in pharmacy.
5
3 Evaporation: Basic concept of phase equilibria, factors affecting evaporation, heat
transfer in evaporators, Duhring’s Rule and Raoult’s law, evaporators- natural circulation
forced circulation & film evaporators, single effect and multiple effect evaporators,
mathematic problems.
8
4 Distillation: Physical concepts, vapour liquid equilibrium relationship, volatility &
relative volatility, simple steam and flash distillations, batch and continuous distillation,
rectification, distillation columns (packed, plate) and their efficiency, McCabe Thiele
method for calculation of number of theoretical plates, azeotropic, molecular & steam
distillation, mathematical problems.
8
5 Drying: Principle, Moisture content, loss on drying, theory & mechanism of drying,
drying rate and time calculations, classification of dryers, factors affecting selection of
dryers, dryers used in pharmaceutical industries - tray, vacuum, fluidized bed, spray,
freeze, tunnel, Microwave, Infra Red(IR), rotary dryers. Mathematical problems on
drying.
8
B. Pharm. Semester – II Syllabus CHARUSAT
FACULTY OF PHARMACY 17
6 HVAC (Humidity Ventilation and Air Conditioning): Definitions of various terms, wet
bulb and adiabatic saturation temperatures, psychrometric chart and determination of
humidity, equipments for humidification and de-humidification operations, applications
of humidity control in various pharmaceutical processes. Basic concepts and types of
refrigeration cycles, air conditioning, applications in pharmacy. Design of HVAC systems.
8
Detailed syllabus (Practical):
No. Aim of Practical
1 To determine specific cake resistance and resistance offered by filter media on rate of
filtration.
2 To study the effect of temperature on rate of filtration
3 To study the effect of filter aids on rate of filtration
4 To find out optimum concentration of filter aid.
5 To study effect of viscosity on rate of filtration.
6 Demonstration of laboratory centrifuge machine.
7 To study effect of temperature on evaporation.
8 To study effect of Surface area on evaporation.
9 To study effect of viscosity on evaporation.
10 To find out EMC, CMC, FMC of given powder.
11 To study effect of surface area on drying.
12 To purify the turpentine oil and find out its molecular weight.
13 To study formation of azeotropic mixture and to separate it using third liquid.
14 Calculation of humidity, %RH, Humid heat, Humid Volume by dry bulb and wet bulb
temperature.
15 To verify Rayleigh’s equation for differential distillation of acetic acid and water.
Recommended study material:
B. Pharm. Semester – II Syllabus CHARUSAT
FACULTY OF PHARMACY 18
1. Perry’s Chemical Engineer’s Handbook; Robert H Perry, Green D.W., Maloney J.O.;
McGraw Hill Inc., New York; 7th Edition, 1998.
2. Copper and Gun’s Tutorial Pharmacy; S. J. Carter; CBS Publication & Distribution, New
Delhi; 2004
3. Pharmaceutical Engineering; K. Sambamurthy; New Age International Ltd., New Delhi
2002.
4. Pharmaceutic the Science of Dosage Form Design; M.E. Aulton; Churchill Livingstone,
London; 2002.
5. The Theory & Practice of Industrial Pharmacy; Lachman L., Lieberman H.A., Kanjig J.L.,
Varghese Publishing House, Bombay; 3rd edition; 1991.
6. Remington: The Science and Practice of Pharmacy; Gennaro A.R.; Lippincott Williams
&Wilkins, Philadelphia; 2004.
7. Pharmaceutics II (Unit Operations); Jani G. K.; B. S. Shah Prakashan, Ahmedabad; 2002
8. Pharmaceutical Engineering : Principles and Practice; Subramanyam C.V.S., Thimma J,
Suresh S.S.; Vallabh Prakashan, Delhi; 2004.
9. Benthley`s Textbook of Pharmaceutics; Rawlins E A; AITBS Pub & Dist Delhi; 2004.
B. Pharm. Semester – II Syllabus CHARUSAT
FACULTY OF PHARMACY 19
Dispensing Pharmacy (PH 110)
(Theory & Practical)
Credits: 3 (Theory) Contact Hours per week: 3 (Theory)
: 1.5 (Practical) : 3 (Practical)
Objective of the course:
To study basic process which are used in different stage during preparation of
pharmaceutical formulation.
Subject gives the guideline for calculation of formulas, labeling, and packing of different
types of pharmaceutical products.
Students learning outcomes/objectives:
By the end of this course, the student should have a good understanding of the basic
concepts of formulation, labeling, packing of different types of pharmaceutical dosage
forms.
Students should be able to know the appropriate dose calculation and drug for patient
Instructional methods and pedagogy:
The lectures will be delivered using
Black board,
Over Head Projector
Multimedia projector
Outline of the course (Theory):
No. Unit Minimum No. of
Contact Hours
Approx
Weightage %
1 Definition and scope 2 5 %
2 The prescription 4 10 %
2 Dispensing techniques 4 10 %
3 Pharmaceutical calculations 8 15 %
B. Pharm. Semester – II Syllabus CHARUSAT
FACULTY OF PHARMACY 20
4 Principles involved and procedures adopted in
dispensing of various pharmaceutical preparations 16
40 %
5 Incompatibilities 11 20 %
Total 45 100 %
Detailed Syllabus (Theory):
No. Unit details Contact
Hours
1 Definition and scope 2
2 The prescription: Handling of prescription, sources of errors in prescription, care
required in dispensing procedures including labeling of dispensed products. 4
3 Dispensing techniques: Compounding and dispensing procedures, packaging, storage
and stability of medicines, labelling of dispensed products 4
4 Pharmaceutical calculations: Posoloy: Calculations of doses for infants, adults &
elderly patients, enlarging and reducing recipes, percentage solutions, allegation,
alcohol dilution, proof spirit, isotonic solutions, displacements value etc.
8
5 Principles involved and procedures adopted in dispensing of: Liquid Products
(Mixtures, solutions, emulsions, suspensions) external preparations, suppositories &
pessaries, powders and granules, oral unit dosage forms, inhalations.
16
6 Incompatibilities: Physical, chemical and therapeutic incompatibilities observed in
prescriptions of above products: (a) Identifications and correction of incompatibilities.
(b) Inorganic incompatibilities including incomp. of metals and their salts, non metals,
acids, alkalis. (c) Organic incompatibilities: Purine bases, alkaloids, pyrazolone
derivatives, amino acids, quaternary ammonium compounds, carbohydrates,
glycosides, anesthetics, dyes, surface active agents.
11
Detailed syllabus (Practical):
No. Aim of Practical
B. Pharm. Semester – II Syllabus CHARUSAT
FACULTY OF PHARMACY 21
1 Introduction
- General dispensing procedure
- Weights and measures
- Fundamental operations in Dispensing
- Household measurements
- Study of prescription in general
2 Preparation, labeling and packing of Oral & external solutions
3 Preparation, labeling and packing of solutions used for oral cavities
4 Preparation, labeling and packing of solutions used for nose, ear, eye, rectum, vagina etc.
5 Preparation, labeling and packing of suspensions containing diffusible Solids, in-diffusible
solids, poorly wettable solids.
6 Preparation, labeling and packing of suspensions containing precipitate forming liquids,
suspensions prepared by chemical reaction etc.
7 Preparation, labeling packing of emulsion containing fixed oil, volatile oil, both types of oil,
mineral oil etc.
8 Preparation, labeling & packing of external emulsions.
9 Preparation, labeling and packing of ointments containing Hydrocarbon
Base, water miscible base, absorption base and water soluble base.
10 Preparation labeling & packing of Non-staining ointments, paste, gel, cold cream,
vanishing cream etc.
11 a) To determine the mould capacity
b) To determine the Displacement value
c) Preparation, labeling and packing of Coca butter Suppositories
containing soluble, insoluble, semisolid substances etc.
12 Preparation, labeling & packing of suppositories containing gelatoglycein,
Soap glycerin and macrogol base.
13 Preparation, labeling and packing of Bulk powders, Divided powders etc.
B. Pharm. Semester – II Syllabus CHARUSAT
FACULTY OF PHARMACY 22
No. Aim of Practical
14 a) Preparation, labeling and packing of effervescent granules
b) Preparation of Tablet triturates by moulding
c) Preparation of lozenges
15 Evaluating given prescriptions for drug interactions
Recommended study material: 1. Pharmaceutical Practice; Diana M. Collett, Michale E.Aulton; ELBS Pubilshers.
2. Dispensing for pharmaceutical students” by Copper and Gunn by S.J.Carter, 12th Edn.
CBS Publishers.
3. “Pharmaceutical Calculations” by Mitchell J. Stklosa & Howard C.Ansel by Lippincott
Williams & Wilkins.
4. “Pharmaceutical Dosage forms and Drug delivery systems” by Howard C. Ansel by
Lippincott Williams & Wilkins.
5. “Pharmaceutical Practice” Edited by A.J. Winfield & R.M.E. Richardes.
6. “Remington: The Science and Practice of Pharmacy” Latest edn. by Mack Publishing
Company.
7. Pharmacy Practice by Stone and Cartis.
8. Copper and Gun’s Tutorial Pharmacy by S.J.Carter.
B. Pharm. Semester – II Syllabus CHARUSAT
FACULTY OF PHARMACY 23
Advanced Mathematics (MA 141)
Credits: 3 Contact Hours per week: 3
Objective of the Course:
To introduce the basic concepts of Mathematics to students passing HSC with B-group.
Pre-requisite:
No additional Pre-requisite required.
Methodology:
The emphasis during Lecture sessions will be on Understanding of Concepts rather than on
complexities of Computational Techniques. Stress is also given on Visual perception through
Mathematical Software. Relevant Illustrations will be provided from the Real World processes.
Sufficient home assignments will be given to the students which will test their fundamentals
and ability to relate Mathematical concepts with reality.
Outline of the Course:
No. Unit Minimum No. of
Contact Hours
Approx.
Weightage %
1 Higher order derivatives and applications 6 15 %
2 Mean value theorems and expansion of functions
8 20 %
3 Laplace Transforms 6 15 %
4 Ordinary Differential Equations 6 16 %
5 Linear Differential Equations 8 18 %
6 Mathematical modeling 11 26 %
Total 45 100 %
B. Pharm. Semester – II Syllabus CHARUSAT
FACULTY OF PHARMACY 24
5 Detailed Syllabus:
No. Unit details Contact
hours
1 Higher order derivatives and applications
- Real world problems involving concepts of first and higher order
derivatives
- successive differentiation
- nth derivative of elementary functions viz., rational, logarithmic,
trigonometric, exponential and hyperbolic
- Leibnitz rule for the nth order derivatives of product of two functions.
6
2 Mean value theorems and expansion of functions:
- Lagrange’s and Cauchy mean value theorems
- expansion of functions
- Maclaurin’s & Taylor’s series expansions
8
3 Laplace Transforms:
- Laplace transforms of elementary functions
- Inverse Laplace transforms
- linearity property
- first and second shifting theorem
- Laplace transforms of derivative and integrals
- applications of Laplace transforms in solving ordinary
differential equations
6
4 Ordinary Differential Equations:
- Modelling of real world problems in terms of first order ODE - Initial
Value problems
- Concept of general and particular solutions
- Existence and Uniqueness solutions by illustrations
- linear, Bernoulli and Exact differential equations
6
B. Pharm. Semester – II Syllabus CHARUSAT
FACULTY OF PHARMACY 25
No. Unit details Contact
hours
5 Linear Differential Equations:
- Model of real world problems of higher order LDE
- Complementary function and particular integral
- LDE of higher order with constant coefficients
- Methods for finding particular integrals viz., variation of parameters
and undetermined coefficients
- LDE of higher order with variable coefficients viz., Cauchy’s and
Legendre’s homogeneous linear differential equations
- System of two first order linear differential equations.
8
6 Mathematical modeling:
- Construction of mathematical models
- growth of bacteria
- rate of decay
- Newton’s law of cooling,
- diffusion and fick’s law of diffusion
- effects of immigration and immigration on population size,
- spread of infectious diseases,
- model for diffusion of glucose,
11
Recommended study materials:
1. Calculus and Analytical Geometry; Thomas G. B. and R. L. Finney; Addision Wesley; 9th Ed.,
1996.
2. Advanced Engineering Mathematics, Erwin Kreyszig; Jhon Wiley & Sons, India, 8th Ed., 1999
3. Calculus Early Transcendental; Stewart James; Thomson India, 5th Ed., 2007
4. Advanced Engineering Mathematics; Wylie & Barrett; Mc graw Hill publication.
5. Advanced Engineering Mathematics; Greenberg M D; Pearson Educat, 2nd edition.
B. Pharm. Semester – II Syllabus CHARUSAT
FACULTY OF PHARMACY 26
Communication Skills – II (EN 104) (Theory and Practical)
Credits: 1 (Theory) Contact Hours per week: 1 (Theory)
: 1.5 (Practical) : 3 (Practical)
Objectives of the Course:
To sharpen Communication Skills of the students with reference to Organizational
Structure,
To expose them to the modern modes of communication, and
To prepare the students for Campus Interviews
Instructional Method and Pedagogy:
Lectures will be taken in class room and practicals will be conducted in the language lab
with the use of multi-media presentations / black board work and mix of both.
Some assignments and Presentation Tasks will be given.
Students will also be engaged in interpersonal communication activities such as group
discussion, role plays, simulations, just a minute sessions, etc.
Mock Interviews will be conducted for practice
Outline of the course (Theory and Practical):
No. Unit
Minimum No.
contact of
hours
Approx.
Weightage %
1. The Internet, Communication, and Contemporary
Society
07 8 %
2. Advanced Interpersonal and Organizational
Communication
07 9 %
3. Group Communication and Group Dynamics 05 9 %
4. Advanced Report Writing 07 16 %
5. Effective Presentation Strategies 10 16 %
B. Pharm. Semester – II Syllabus CHARUSAT
FACULTY OF PHARMACY 27
6. Group Discussion 08 16 %
7. Interview Skills 08 15 %
8. Applying Communication to Internships in
Organizations
08 11 %
Total 60 100 %
Detailed Syllabus (Theory and Practical):
No. Unit details Contact
Hours
1 The Internet, Communication, and Contemporary Society:
An Introduction to Modern Day Communication
Theories of group and community communication
Understanding Internet communication and its social implications
Basic terms, concepts, and contexts of Internet Communication
07
2 Advanced Interpersonal and Organizational Communication :
Introduction to Interpersonal and Organizational Communication
Levels of Communication
Essentials of Organizational Communication
07
3 Group Communication and Group Dynamics :
Introduction to Group Communication
Introduction to Group Dynamics
Communication Networks within and outside the Groups
Social & Behavioural Sciences and Group Communication
05
B. Pharm. Semester – II Syllabus CHARUSAT
FACULTY OF PHARMACY 28
4 Advanced Report Writing:
An introduction to Report Writing
Types of Reports
Organizing Information & Collaborative Writing
Drafting and Revising Documents for Grammar, Mechanics and Coherence
Designing effective documents and visuals
07
5 Effective Presentation Strategies:
Why and How in Presentation
Presentation Mechanics and Presentation Process
Managing Yourself during Q and A Session
Fundamentals of Persuasions
10
6 Group Discussion:
Introduction to Group discussions
Group Discussion as a part of the selection process
Guidelines for group discussion
Roles and functions in group discussion
08
7 Interviews:
Introduction to Interviews
General preparations for an interview
Types of questions generally asked at the interviews
Types of interviews
Importance of nonverbal aspects
08
8 Applying Communication to Internships in Organizations:
Communication in Organizations
Role of Communication in Organizations
Theories of interpersonal communication and organization structures
Communication Management in an Organization
08
B. Pharm. Semester – II Syllabus CHARUSAT
FACULTY OF PHARMACY 29
Recommended Study Material:
Reference reading:
1. Effective English for Engineers and Technologists; Dr. Rai Ajay.
2. Spoken English 2nd Edition; Sreevalsan M. C.
3. English for Technical Communication Volume 2&2 Combined; Laxminarayan R. K.
Additional Reading:
4. English for Technical Communication Volume 2&2 Combined; Laxminarayan R. K.
5. Longman Dictionary of Common Errors; Turton N. D.
6. Learning to Communicate: A Resource Book for Scientists and Technologists English 1 &
2; Chellammal V.
B. Pharm. Semester – II Syllabus CHARUSAT
FACULTY OF PHARMACY 30
Engineering Graphics (PH 111)
(Practical)
Credits: 1.5 (Practical) Contact Hours per week: 3 (Practical)
Objective of the course:
To study basic fundamental of engineering drawing.
To study the making and reading of drawings
Students learning outcomes/objectives:
By the end of this course, the student should have a good understanding of the
basic concepts of engineering drawing.
Students should gain knowledge of the appropriate operating procedure of
engineering drawing.
Instructional methods and pedagogy:
The lectures will be delivered using
Black board,
Over Head Projector
Multimedia projector Detailed syllabus (Practical):
Sr. No. List of Practical
01 Introduction to Engineering Graphics
Instrument used in Engineering Drawing
02 Lay out of Drawing Sheet and Line, Letters and Numbers
03 Scale and Dimensions
04 Introduction of Orthographic Projections
Principle of first and third angle projection with example
05 Introduction of Isometric Projections
B. Pharm. Semester – II Syllabus CHARUSAT
FACULTY OF PHARMACY 31
Isometric view and Isometric projection with example
06 Sectioning
07 Overview of computer aided drafting and 3D Modeling
Recommended study material:
1. Engineering Drawing; N. D. Bhatt; Charotar publishing house, Anand; 2006
2. Engineering Drawing and Graphics; K Venugopal; New Age International, New Delhi; 4th
Edition; 2003.
3. Machine Drawing for Pharmacy Students; K.Sampath, Birla Publications Pvt. Ltd., New
Delhi; 2nd Edition; 2008.