chapt11holeslecture1-091122123910-phpapp01
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BIOL 2064:Anatomy & Physiology 1
Chapter 11
Edited by Brenda Holmes
MSN/Ed, RN
Associate Professor
South Aransas Community College
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!ole"s !uman Anatomy
an# Physiology$%elth '#ition
Shier Butler Le%is
Chapter
11
(er)ous System II: *i)isionso the (er)ous System
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11+1: Intro#u,tion
!e central ner"o#s system $%NS& consists of t!e brain
and s'inal cord(
!e brainstem connects t!e brain to t!e s'inal cord(
%omm#nication to t!e 'eri'!eral ner"o#s system $PNS&
is by )ay of t!e s'inal cord(
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11+2: -eninges
!e menin+esMembranes of %NSProtect t!e %NS!ree $3& layers
-#ra mater.o#+! mot!er0eno#s sin#sesal
Arac!noid mater.S'ider)ebli4e
S'ace containscerebros'inal fl#id
$%S&Pia mater
.ait!f#l mot!er
Enca's#lates blood"essels
Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.
Scalp
Cranium
Cerebrum
Cerebellum
Spinal cord
Meninges
Meninges
Cerebrum
(b)(a)
Gray matter
White matter
Subarachnoid space
Falx cerebri
Pia mater
Dura mater
Bone o s!ull
Subcutaneous tissue
S!in
"entorium
cerebelli
#ertebra
Dural sinus (superior
sagittal sinus)
$rachnoid
granulation
$rachnoid
mater
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-eninges o the Spinal Cor#Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.
Spinal cord
Spinal cord
Pia mater
$rachnoid mater
Dura mater
Dorsal root
Dorsal root
Spinal ner%e
&pidural space
(a) (b)
#entral root
Dorsal root
ganglion
"horacic
%ertebra
Spinal
ner%e
Dorsal rootganglion
Subarachnoid
space
Dorsal branch
(dorsal ramus)
#entral branch
(%entral ramus)
#entral root
&pidural
space
Body o
%ertebra
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11+.: /entri,les
an# Cererospinal lui#!ere are fo#r $*& "entricles!e "entricles are interconnected
ca"ities )it!in cerebral !emis'!eres and
brain stem!e "entricles are contin#o#s )it! t!e
central canal of t!e s'inal cord!ey are filled )it! cerebros'inal fl#id
$%S&
!e fo#r $*& "entricles are
7ateral "entricles $2&8no)n as t!e first and
second "entricles!ird "entricleo#rt! "entricle
9nter"entric#lar foramen%erebral a:#ed#ct
'ateral %entricle
"hird %entricle
Fourth %entricle
(a)
nter%entricular
oramen
Cerebralaueduct
"o central canal
o spinal cord
Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.
"hird %entricle
(b)
Cerebral
aueduct
"o central canalo spinal cord
Fourth
%entricle
'ateral
%entricle
nter%entricularoramen
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Cererospinal lui#
Secreted by t!e c!oroid 'le#s
$%an yo# recall t!e s'ecific cells
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11+1 Clini,al Appli,ation
Cererospinal lui# Pressure
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11+4: Spinal Cor#
Slender col#mn of ner"o#s
tiss#e contin#o#s )it! brain
and brainstem
Etends do)n)ard t!ro#+!"ertebral canalBe+ins at t!e foramen
ma+n#m and terminates at t!e
first and second l#mbar
"ertebrae $71/72& inters'ace
Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.
Brainstem
Spinal cord
(a) (b)
Foramen
magnum
Cer%icalenlargement
#ertebral
canal
'umbar
enlargementConus
medullaris
Cauda
euinaFilum
terminale
Conus
medullaris
'umbar
enlargement
Cer%icalenlargement
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Stru,ture o the Spinal Cor#
Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.
White matter
Gray matter
'ateral uniculus
Posterior uniculus
Gray commissure
Central canal
(a)
Posterior horn
Dorsal root
o spinal ner%e
Dorsal root
ganglion
#entral root
o spinal ner%e
$nterior
horn
$nterior
median
issure
Portion o
spinal ner%e
$nterior
uniculus
Posterior median
sulcus
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un,tions o Spinal Cor#
%enter for s'inal reflees
%ond#it for ner"e im'#lses to and from t!e brain and
brainstem
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ele3 Ar,s
Reflees are a#tomatic, s#bconscio#s res'onses to stim#li
)it!in or o#tside t!e bodySim'le refle arc $sensory @ motor&
Most common refle arc $sensory @ association @ motor&Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.
+eceptor
(a)
Sensory or
aerent neuron
Motor or
eerent neuronCentral
,er%ous
System
&ector
(muscle or gland)
13
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ele3 Ar,s
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eneral Components o a
Spinal ele3
+eceptor
Sensory neuron
Motor neuron
White matter
Gray matter
Spinal cord
Dorsalnterneuron
-
.
/
0
1
(b)
Cell body
o sensory
neuron
&ector
(muscle
or gland)
Central
canal
#entral
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ele3 Beha)ior
Eam'le is t!e knee-jerk reflexSim'le monosyna'tic refleHel's maintain an #'ri+!t 'ost#re
Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.
Spinal cord
Patella
Patellar ligamentDirection o impulse
$xon o sensoryneuron
Cell body o
sensory neuron Cell body omotor neuron
$xon o motor
neuron
&ector (uadriceps emorismuscle group)
+eceptor associated 2ith
dendrites o sensory neuron
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ele3 Beha)iorEam'le is a withdrawal reflexPre"ents or limits tiss#e dama+e
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nterneuron
Spinal cord
$xon o sensory neuron
Cell body o sensory neuron
Dendrite o
sensory
neuron
Pain
receptor
in s!in
Directiono impulse
Cell body o
motor neuron
$xon omotor neuron
&ector (lexor
muscle contracts
and 2ithdra2s part
being stimulated)
"ac!
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ele3 Ar,
Eam'le crossed extensor reflex%rossin+ of sensory im'#lses )it!in t!e refle center to
'rod#ce an o''osite effect Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.
3 Stimulation
3 nhibition
nterneuron
Flexor contracts
Sensory neuron
4
4
4
5
5
5
Motor
neurons
&xtensorcontracts
Flexor
relaxes
Motor
neurons
&xtensor
relaxes
1>
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11+2 Clini,al Appli,ation
5ses o ele3es
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$ra,ts o the Spinal Cor#Ascendin+ tracts cond#ct sensory im'#lses to t!e brain-escendin+ tracts cond#ct motor im'#lses from t!e brain to
motor ne#rons reac!in+ m#scles and +landsCopyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.
Posterior spinocerebellar tract
'ateral corticospinal tract
'ateral reticulospinal tract+ubrospinal tract
$nterior spinocerebellar tract
'ateral spinothalamic tract
$nterior reticulospinal tract
Medial reticulospinal tract
Fasciculus cuneatus
Fasciculus gracilisDorsal column
$nterior spinothalamic tract$nterolateral
system
$nterior
corticospinaltract
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As,en#ing $ra,ts
Maor ascendin+ $sensory&
s'inal cord tractsascic#l#s +racilis and
fascic#l#s c#neat#sS'inot!alamic tracts
7ateral and anteriorS'inocerebellar tracts
Posterior and anterior
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Midbrain
Pons
Medulla
"halamus
Sensory
cortex o
cerebrum
Cerebrum
(rontal
section)
Brainstem
(trans%erse
sections)
Spinal cord
(trans%erse section)
Sensory ibers
cross o%er
Spinothalamic
tract
Fasciculuscuneatus
tract
Sensory
impulse
rom s!in
temperature
or pain
receptors
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*es,en#ing $ra,ts
Maor descendin+ $motor& s'inal
cord tracts%orticos'inal tracts
7ateral and anteriorRetic#los'inal tracts
7ateral, anterior and medialR#bros'inal tract
Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.
Midbrain
Pons
Brainstem
(trans%erse
sections)
Spinal cord
(trans%erse section)
Motor cortex
o cerebrum
Cerebrum
(rontal
section)
Corticospinal
tract
Medullaoblongata
Motor ibers
cross o%er
Motor
impulse tos!eletal
muscle
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(er)e $ra,ts o the Spinal Cor#
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11+. Clini,al Appli,ation
Spinal Cor# Inuries
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11+7: Brain
#nctions of t!e brain9nter'rets sensations-etermines 'erce'tion
Stores memoryReasonin+Ma4es decisions%oordinates m#sc#lar mo"ements
Re+#lates "isceral acti"ities-etermines 'ersonality
Maor 'arts of t!e brain%erebr#m
rontal lobes
Parietal lobescci'ital lobesem'oral lobes9ns#la
-ience'!alon%erebell#mBrainstem
MidbrainPonsMed#lla oblon+ata
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$he BrainCopyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.
Cerebrum
Diencephalon
Midbrain
Pons
Medulla oblongata
Spinal cord
Cerebellum
Fornix
(b)
S!ull
Meninges
Cerebrum
Diencephalon
Brainstem
(a)
Sulcus
Gyrus
Fornix
Cerebellum
Spinal cord
Midbrain
Pons
Medulla
oblongata
Corpus
callosum
Corpuscallosum
"rans%erse issure
!" Martin M. #ot$er%Photo #esearchers, Inc.
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Brain *e)elopment
Ne#ral t#be!ree 'rimary "esicles
orebrain
$Prosence'!alon&
Midbrain
$Mesence'!alon&Hindbrain
$R!ombence'!alon&
i"e secondary "esicleselence'!alon-ience'!alonMesence'!alonMetence'!alonMyelence'!alon
Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.
Prosencephalon (orebrain)
Mesencephalon (midbrain)
+hombencephalon (hindbrain)
,eural tube
(a)
Diencephalon
Mesencephalon
Myelencephalon
Metencephalon
,eural tube
(b)
"elencephalon
(c)
Diencephalon
Midbrain
Pons and Cerebellum
Spinal cord
Cerebral
hemispheres
Medulla
oblongata
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Brain *e)elopment
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Stru,ture o the Cererum%or'#s callos#m
%onnects cerebral
!emis'!eres $a commiss#re&Cyri
B#m's or con"ol#tionsS#lci
Croo"es in +ray matter%entral s#lc#s of
Rolando
iss#res7on+it#dinal se'arates t!e
cerebral !emis'!eresrans"erse se'arates
cerebr#m from cerebell#m
7ateral fiss#re of Syl"i#s
Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.
Central sulcus
Gyrus
Sulcus
Frontal lobe
'ateral sulcus
Parietal lobe
6ccipital lobe
Central sulcus
Parietal lobe
6ccipital lobe
(a)
(b) (c)
Parietal lobe
Central sulcus
6ccipital lobeFrontal lobe
nsula
"emporal lobe
'ongitudinal
issure
"rans%erse
issureCerebellar
hemisphere
+etracted
temporal lobe
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Loes o the Cererum
i"e $5& lobes bilaterallyrontal lobeParietal lobeem'oral lobecci'ital lobe9ns#la a4aD9sland of
Reil
Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.
(c)
Parietal lobe
Central sulcus
6ccipital lobe
Frontal lobe
nsula
+etracted
temporal lobe
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un,tions o the Cererum
9nter'retin+ im'#lses9nitiatin+ "ol#ntary mo"ementsStorin+ information as memory
Retrie"in+ stored informationReasonin+Seat of intelli+ence and 'ersonality
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un,tional egions o the
Cereral Corte3%erebral corte
!in layer of +ray matter t!at constit#tes t!e o#termost
'ortion of cerebr#m
%ontains ;5F of all ne#rons in t!e ner"o#s systemCopyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.
Frontal eye ield
Central sulcus
Parietal lobe
6ccipital lobe
Cerebellum
Brainstem
nterpretation o auditory patterns
'ateral sulcus
$uditory area
Sensory areas in%ol%ed 2ith
cutaneous and other senses
Sensory speech area( Wernic!e7s area)
Combining
%isual images8
%isual recognition
o ob9ects
#isual area
"emporal lobe
Motor speech area
(Broca7s area)
Motor areas in%ol%ed 2ith the control
o %oluntary muscles
Concentration8 planning8
problem sol%ing
Front lobe
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un,tions o the Cereral Loes
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Sensory Areas
8post9,entral sul,us%#taneo#s sensory areaParietal lobe9nter'rets sensations on
s4in
0is#al areacci'ital lobe9nter'rets "ision
A#ditory areaem'oral lobe9nter'rets !earin+
Sensory area for tasteNear base of t!e central s#lc#s
Sensory area for smellArises from centers dee' )it!in
t!e cerebr#mCopyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.
Frontal eye ield
Central sulcus
Parietal lobe
6ccipital lobe
Cerebellum
Brainstem
nterpretation o auditory patterns
'ateral sulcus
$uditory area
Sensory areas in%ol%ed 2ith
cutaneous and other senses
Sensory speech area( Wernic!e7s area)
Combining%isual images8%isual recognition
o ob9ects
#isual area
"emporal lobe
Motor speech area
(Broca7s area)
Motor areas in%ol%ed 2ith the controlo %oluntary muscles
Concentration8 planning8
problem sol%ing
Front lobe
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Sensory AreasCopyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.
Parietal lobe
Sensory area
Central sulcus
Motor area
Frontal lobe
S2allo2ing
Forearm
$rmPel%is
"high
'eg
'ips
Forearm $rm,ec! Pel%is
"high
'eg
Genitals
(a) Motor area (b) Sensory area
'ongitudinalissure
Sali%ation#ocali:ation
Mastication
Facial
expression
"humb8
ingers8
and hand
"run!
Foot and
toes
"ongue andpharynx
"eeth andgums
;pper
ace
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Asso,iation Areas
Re+ions t!at are not 'rimary motor or 'rimary sensory areasGides'read t!ro#+!o#t t!e cerebral corteAnalye and inter'ret sensory e'eriencesPro"ide memory, reasonin+, "erbaliation, #d+ment, emotions
Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.
Frontal eye ield
Central sulcus
Parietal lobe
6ccipital lobe
Cerebellum
Brainstem
nterpretation o auditory patterns
'ateral sulcus
$uditory area
Sensory areas in%ol%ed 2ith
cutaneous and other senses
Sensory speech area
( Wernic!e7s area)
Combining
%isual images8
%isual recognition
o ob9ects
#isual area
"emporal lobe
Motor speech area
(Broca7s area)
Motor areas in%ol%ed 2ith the control
o %oluntary muscles
Concentration8 planning8
problem sol%ing
Front lobe
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Asso,iation Areas
rontal lobe association areas%oncentratin+Plannin+%om'le 'roblem sol"in+
Parietal lobe association areasInderstandin+ s'eec!%!oosin+ )ords to e'ress
t!o#+!t
em'oral lobe association areas9nter'ret com'le sensory
e'eriencesStore memories of "is#al scenes,
m#sic, and com'le 'atterns
cci'ital lobe association areasAnalye and combine "is#al
ima+es )it! ot!er sensory
e'eriences
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3;
-otor Areas
8pre9,entral sul,usPrimary motor areas
rontal lobes%ontrol "ol#ntary m#scles
Brocas areaAnterior to 'rimary motor
corteIs#ally in left !emis'!ere%ontrols m#scles needed for
s'eec!
rontal eye fieldAbo"e Brocas area%ontrols "ol#ntary mo"ements
of eyes and eyelids
Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.
Frontal eye ield
Central sulcus
Parietal lobe
6ccipital lobe
Cerebellum
Brainstem
nterpretation o auditory patterns
'ateral sulcus
$uditory area
Sensory areas in%ol%ed 2ith
cutaneous and other senses
Sensory speech area
( Wernic!e7s area)
Combining
%isual images8
%isual recognition
o ob9ects
#isual area
"emporal lobe
Motor speech area
(Broca7s area)
Motor areas in%ol%ed 2ith the control
o %oluntary muscles
Concentration8 planning8
problem sol%ing
Front lobe
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3>
-otor AreasCopyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.
Parietal lobe
Sensory area
Central sulcus
Motor area
Frontal lobe
S2allo2ing
Forearm
$rmPel%is
"high
'eg
'ips
Forearm $rm,ec! Pel%is
"high
'eg
Genitals
(a) Motor area (b) Sensory area
'ongitudinalissure
Sali%ation#ocali:ation
Mastication
Facial
expression
"humb8
ingers8
and hand
"run!
Foot and
toes
"ongue andpharynx
"eeth andgums
;pper
ace
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!emisphere *ominan,e
!e left !emis'!ere is dominant in most indi"id#als
-ominant !emis'!ere controls
S'eec!Gritin+Readin+0erbal s4illsAnalytical s4ills%om'#tational s4ills
Nondominant !emis'!ere controls
Non"erbal tas4sMotor tas4sInderstandin+ and inter'retin+
m#sical and "is#al 'atternsPro"ides emotional and int#iti"e
t!o#+!t 'rocesses
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-emory
S!ort term memoryGor4in+ memory%losed ne#ronal circ#it
%irc#it is stim#lated o"er ando"erG!en im'#lse flo) ceases,
memory does also #nless it
enters lon+term memory "ia
memory consolidation
7on+ term memory%!an+es str#ct#re or
f#nction of ne#rons
En!ances syna'tictransmission
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11+4 Clini,al Appli,ation
$raumati, Brain Inury
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Basal (u,lei
Masses of +ray matter-ee' )it!in cerebral
!emis'!eres
%a#date n#cle#s,'#tamen, and +lob#s
'allid#sProd#ce do'amine%ontrol certain m#sc#lar
acti"itiesPrimarily by
in!ibitin+ motor
f#nctions
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"halamus
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*3
*ien,ephalon
Bet)een cerebral !emis'!eres and abo"e t!e brainstemS#rro#nds t!e t!ird "entricle
!alam#s
E'it!alam#sHy'ot!alam#s'tic tracts'tic c!iasm
9nf#ndib#l#mPosterior 'it#itaryMammillary bodiesPineal +land
Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.
Pyramidal tract
Pons
6ptic ner%e6ptic chiasma
"halamus
Spinal cord
Pituitary gland
Pineal gland
6ptic tract
Mammillary body
(a) (b)
6li%e
Corpora uadrigemina
Cerebral
peduncles
Superior
colliculus
neriorcolliculus
"hird
%entricle
Fourth%entricle
Cerebellarpeduncles
Medulla
oblongata
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*ien,ephalon
!alam#sCate)ay for sensory im'#lses !eadin+ to cerebral corteRecei"es all sensory im'#lses $ece't smell&
%!annels im'#lses to a''ro'riate 'art of cerebral corte forinter'retation
Hy'ot!alam#sMaintains !omeostasis by re+#latin+ "isceral acti"ities7in4s ner"o#s and endocrine systems $!ence some say t!e
ne#roendocrine system
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*5
*ien,ephalon
%onsists of
Portions of frontal lobePortions of tem'oral lobeHy'ot!alam#s!alam#sBasal n#cleit!er dee' n#clei
#nctions
%ontrols emotionsProd#ces feelin+s9nter'rets sensory im'#lses
$he Limi, System
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*6
11+7 Clini,al Appli,ation
Parinson *isease
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*;
Brainstem
!ree 'arts
1( Midbrain
2( Pons
3( Med#lla blon+ata
Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.
Spinal cord
"halamus
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*>
-i#rain
Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.
Pyramidal tract
Pons
6ptic ner%e6ptic chiasma
"halamus
Spinal cord
Pituitary gland
Pineal gland
6ptic tract
Mammillary body
(a) (b)
6li%e
Corpora uadrigemina
Cerebral
peduncles
Superiorcolliculus
nerior
colliculus
"hird%entricle
Fourth
%entricle
Cerebellarpeduncles
Medulla
oblongata
Bet)een dience'!alon and 'ons%ontains b#ndles of fibers t!at
oin lo)er 'arts of brainstem and
s'inal cord )it! !i+!er 'art of
brain
%erebral a:#ed#ct%erebral 'ed#ncles $b#ndles of
ner"e fibers&%or'ora :#adri+emina $centers
for "is#al and a#ditory reflees&
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*?
Pons
Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.
Pyramidal tract
Pons
6ptic ner%e6ptic chiasma
"halamus
Spinal cord
Pituitary gland
Pineal gland
6ptic tract
Mammillary body
(a) (b)
6li%e
Corpora uadrigemina
Cerebralpeduncles
Superior
colliculus
neriorcolliculus
"hird
%entricle
Fourth%entricle
Cerebellar
peduncles
Medullaoblongata
Ro#nded b#l+e on #nderside of
brainstemBet)een med#lla oblon+ata and
midbrainHel's re+#late rate and
de't! of breat!in+Relays ner"e im'#lses to and from
med#lla oblon+ata and cerebell#m
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-e#ulla Olongata
Enlar+ed contin#ation of
s'inal cord%ond#cts ascendin+ and
descendin+ im'#lses bet)een
brain and s'inal cord%ontains cardiac,
"asomotor, and res'iratory
control centers%ontains "ario#s non"ital
refle control centers
$co#+!in+, sneein+,
s)allo)in+, and "omitin+&
Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.
Pyramidal tract
Pons
6ptic ner%e6ptic chiasma
"halamus
Spinal cord
Pituitary gland
Pineal gland
6ptic tract
Mammillary body
(a) (b)
6li%e
Corpora uadrigemina
Cerebralpeduncles
Superior
colliculus
neriorcolliculus
"hird
%entricle
Fourth%entricle
Cerebellar
peduncles
Medullaoblongata
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eti,ular ormation
%om'le net)or4 of ner"e
fibers scattered t!ro#+!o#t t!e
brain stemEtends into t!e dience'!alon
%onnects to centers of!y'ot!alam#s, basal n#clei,
cerebell#m, and cerebr#milters incomin+ sensory
informationAro#ses cerebral corte intostate of )a4ef#lness
Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.
Spinal cord
"halamus
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$ypes o Sleep
Slo) )a"eNonREM slee'Person is tired
-ecreasin+ acti"ity ofretic#lar systemRestf#l-reamlessRed#ced blood 'ress#re and
res'iratory rateRan+es from li+!t to !ea"yAlternates )it! REM slee'
Ra'id Eye Mo"ement $REM&Paradoical slee'Some areas of brain acti"e
Heart and res'iratory ratesirre+#lar-reamin+ occ#rs
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Cereellum
9nferior to occi'ital lobesPosterior to 'ons and med#lla
oblon+ata)o !emis'!eres0ermis connects !emis'!eres
%erebellar corte $+ray matter&Arbor "itae $)!ite matter&%erebellar 'ed#ncles $ner"e fiber
tracts&-entate n#cle#s $lar+est n#cle#s in
cerebell#m&9nte+rates sensory information
concernin+ 'osition of body 'arts%oordinates s4eletal m#scle acti"ityMaintains 'ost#re
Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.
"halamus
Superior peduncle
Middle peduncle
nerior peduncle
Pons
Medulla oblongata
Cerebellum
Corpus callosum
'ongitudinal
issure
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5*
-aor Parts o the Brain
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11+6: Peripheral (er)ous System
%ranial ner"esarisin+ from t!e brainSomatic fibers connectin+ to t!e s4in and s4eletal m#sclesA#tonomic fibers connectin+ to "iscera
S'inal ner"esarisin+ from t!e s'inal cordSomatic fibers connectin+ to t!e s4in and s4eletal m#sclesA#tonomic fibers connectin+ to "iscera
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5;
(er)ous System Su#i)isions
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Stru,ture o a Peripheral (er)eCopyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.
Peripheral ner%e
&pineurium
$xon
,eurilemma
Myelin sheath
Sch2ann cell
,ode o +an%ier
&ndoneurium
Perineurium
Fascicle
Sensory receptor
Motor neuron
ending
( # ( i
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5?
(er)e an# (er)e ier
Classii,ation
Sensory ner"es%ond#ct im'#lses into brain or s'inal cord
Motor ner"es%ond#ct im'#lses to m#scles or +lands
Mied $bot! sensory and motor& ner"es%ontain bot! sensory ner"e fibers and motor ner"e fibers
Most ner"es are mied ner"esA77 s'inal ner"es are mied ner"es $ece't t!e first 'air&
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(er)e ier Classii,ation
Ceneral somatic efferent $CSE& fibers%arry motor im'#lses from %NS to
s4eletal m#scles
Ceneral "isceral efferent $C0E& fibers%arry motor im'#lses a)ay from
%NS to smoot! m#scles and +lands
Ceneral somatic afferent $CSA& fibers%arry sensory im'#lses to %NS from
s4in and s4eletal m#scles
Ceneral "isceral afferent $C0A& fibers%arry sensory im'#lses to %NS from
blood "essels and internal or+ans
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Cranial (er)esCopyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.
6lactory bulb
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Cranial (er)es
Remember
%ranial ner"es are desi+nated D% N
%ranial ner"es are desi+nated )it! Roman n#merals$9 @ J99&
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6*
Cranial (er)es I an# II
lfactory ner"e $%N 9&Sensory ner"eibers transmit im'#lses
associated )it! smell
'tic ner"e $%N 99&Sensory ner"eibers transmit im'#lses
associated )it! "ision
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Cranial (er)es III an# I/
roc!lear ner"e $%N 90&Primarily motor ner"eMotor im'#lses to m#scles
t!at mo"e t!e eyesSome sensory
Pro'rioce'tors
c#lomotor ner"e $%N 999&Primarily motor ner"eMotor im'#lses to m#scles
t!atRaise eyelidsMo"e t!e eyesoc#s lensAd#st li+!t enterin+ eye
Some sensoryPro'rioce'tors
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Cranial (er)e /
ri+eminal ner"e $%N 0&Mied ner"e.!ree $3& sisters$1& '!t!almic di"ision
Sensory from s#rface of eyes,
tear +lands, scal', fore!ead,and #''er eyelids
$2& Maillary di"isionSensory from #''er teet!,
#''er +#m, #''er li', 'alate,
and s4in of face
$3& Mandib#lar di"isionSensory from scal', s4in of
a), lo)er teet!, lo)er +#m,
and lo)er li'
Motor to m#scles of
mastication and m#scles infloor of mo#t!
Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.
'acrimal ner%e
&ye
Maxilla
Mandible
'acrimal
gland
nraorbital
ner%e
"ongue
Mental
ner%e
6phthalmic
di%ision
Maxillary
di%ision
Mandibular
di%ision
'ingual
ner%e
nerior
al%eolar
ner%e
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Cranial (er)es /I an# /II
Abd#cens ner"e $%N 09&Primarily motor ner"eMotor im'#lses to m#scles
t!at mo"e t!e eyesSome sensory
Pro'rioce'tors
acial ner"e $%N 099&Mied ner"eSensory from taste rece'torsMotor to m#scles of facial
e'ression, tear +lands, andsali"ary +lands
Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.
>ygomatic ner%e
Buccal ner%e
Facial ner%e
Mandibular ner%e
Cer%ical ner%e
"emporal ner%e
Posterior auricular
ner%e
Parotid sali%ary
gland
6>
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Cranial (er)es /III an# I cer"ical ner"es
$%1 to %>&12 t!oracic ner"es
$1 to 12&5 l#mbar ner"es
$71 to 75&5 sacral ner"es$S1 to S5&
1 coccy+eal ner"e$%o or %c&
Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.
Cauda euina
C1C0C/C-C.C@CAC"1
"0
"/
"-
".
"@
"A
"
"
"1
"11
"10
'1
'0
'/
'-
'.
S0S/
S-
S1
S.Co
Posterior%ie2
Cer%ical
ner%es
"horacic
ner%es
'umbar
ner%es
Sacral
ner%es
Coccygeal
ner%e
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;3
Spinal (er)es
-orsal root $a4a'osteriorroot&
Sensory rootAons of sensory
ne#rons are in t!e dorsal
root +an+lion-orsal root +an+lion
A4a -RC%ell bodies of sensory
ne#rons )!ose aons
cond#ct im'#lses in)ardfrom 'eri'!eral body 'arts
Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.
'ateral horn
#entral root(a)
(b)
Dorsal root
Dorsal root
Spinal ner%e
Dorsal root
ganglion
Posteriormedian sulcus
Posterior
horn
$nterior
horn
Central
canal
$nteriormedian
issure
Dorsal branch
o spinal ner%e
#entral branch
o spinal ner%e
#isceral brancho spinal ner%e
Para%ertebral
ganglion
#entral branch
o spinal ner%e (%entral ramus)
Dorsal branch
o spinal ner%e (dorsal ramus)
Para%ertebral
ganglion#isceral branch
o spinal ner%e
#entral root
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;*
*ermatome
An area of s4in t!at t!e sensory ner"e fibers of a 'artic#lars'inal ner"e inner"ate
C0C/
C-
C.
C@
"1
C@
CA
S0
S/
C
'1
'0
'/
'-
'.
"10
"1
S1
(a) (b)
S.C
S-S/
S0
S1
'.
'-
'/
'0
'1
'.
'1
C"1
"10
CAC@
C.C-
C/
C0
Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction o r display.
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;5
Spinal (er)es
0entral root $a4aanterior root&Motor rootAons of motor ne#rons
)!ose cell bodies are in t!e
s'inal cord
S'inal ner"eInion of "entral root
and dorsal rootsHence )e no) !a"e a
.mied ner"e
Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.
'ateral horn
#entral root(a)
(b)
Dorsal root
Dorsal root
Spinal ner%e
Dorsal root
ganglion
Posteriormedian sulcus
Posterior
horn
$nterior
horn
Central
canal
$nteriormedian
issure
Dorsal branch
o spinal ner%e
#entral branch
o spinal ner%e
#isceral brancho spinal ner%e
Para%ertebral
ganglion
#entral branch
o spinal ner%e (%entral ramus)
Dorsal branch
o spinal ner%e (dorsal ramus)
Para%ertebral
ganglion#isceral branch
o spinal ner%e
#entral root
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(er)e Ple3uses
Ner"e 'le#s%om'le net)or4s formed by anterior branc!es of s'inal ner"es!e fibers of "ario#s s'inal ner"es are sorted and recombined!ere are t!ree $3& ner"e 'le#ses
$1& %er"ical 'le#sormed by anterior branc!es of %1%* s'inal ner"es7ies dee' in t!e nec4S#''ly to m#scles and s4in of t!e nec4%3%*%5 ner"e roots contrib#te to '!renic ner"es bilaterally
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;;
Bra,hial Ple3us
$2& Brac!ial 'le#sormed by anterior branc!es %5
17ies dee' )it!in s!o#lders!ere are fi"e $5& branc!es1( M#sc#loc#taneo#s ner"e
S#''ly m#scles of anterior arms
and s4in of forearms
2( Ilnar and 3( Median ner"esS#''ly m#scles of forearms and
!ands
S#''ly s4in of !ands*( Radial ner"eS#''ly 'osterior m#scles of arms
and s4in of forearms and !ands
5( Aillary ner"eS#''ly m#scles and s4in of
anterior, lateral, and 'osterior arms
Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.
Musculocutaneous nE
Musculocutaneous nE
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Lumosa,ral Ple3us
$3& 7#mbosacral 'le#sormed by t!e anterior branc!es
of 71S5 roots%an be a l#mbar $7175& 'le#s
and a sacral $S1S5& 'le#s
Etends from l#mbar re+ion into'el"ic ca"itybt#rator ner"e
S#''ly motor im'#lses to
add#ctors of t!i+!s
emoral ner"e
S#''ly motor im'#lses tom#scles of anterior t!i+! and
sensory im'#lses from s4in of
t!i+!s and le+s
Sciatic ner"eS#''ly m#scles and s4in of
t!i+!s, le+s and feet
Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.
Sciatic nE
Saphenous nE
Femoral nE
6bturator nE
"ibial nE
Pudendal nE
(b) (c)(a)
Femoral nE
6bturator nE
Pudendal nE
Sciatic nE
'1
'0
'/
'-
'.
S1
S0
S/
S-
S.
#entralrami
$nterior
di%isions
Posteriordi%isions
'ateralemoral
cutaneous nE
Superior
gluteal nE
nerior
gluteal nE
Superior
gluteal nE
nerior
gluteal nE
Sacralplexus
Commonibular
(peroneal) nE
Posterior
cutaneous nE
Common
ibular
(peroneal) nE"ibial nE
Pl
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;?
Ple3uses
C1C0C/C-
C.C@CAC"1
"0
"/
"-
".
"@
"
"
"1
"11
"10
'1
'0
'/
'-
'.
S0S/S-S.
Co
Posterior %ie2
Cer%ical plexus(C15C-)
'umbosacral plexus("105S.)
Sciatic ner%e
Brachial plexus(C.5"1)
6bturator ner%e
Phrenic ner%e
;lnar ner%e
Median ner%e
+adial ner%e
$xillary ner%e
"A
S1
Cauda euina
Musculocutaneousner%e
Femoralner%e
ntercostalner%es
Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.
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>=
11+= Clini,al Appli,ation
Spinal (er)e Inuries
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>1
11+=: Autonomi, (er)ous System
#nctions )it!o#t conscio#s effort%ontrols "isceral acti"itiesRe+#lates smoot! m#scle, cardiac m#scle, and +lands
Efferent fibers ty'ically lead to +an+lia o#tside of t!e %NS
)o a#tonomic di"isions re+#lateSym'at!etic di"ision $s'eeds #'&
Pre'ares body for Dfi+!t or fli+!t sit#ations
Parasym'at!etic di"ision $slo)s do)n&Pre'ares body for Drestin+ and di+estin+ acti"ities
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>2
Autonomi, (er)e iers
All of t!e ne#rons are
motor $efferent&
Pre+an+lionicfibersAons of 're+an+lionic
ne#ronsNe#ron cell bodies in
%NS
Post+an+lionicfibersAons of 'ost+an+lionic
ne#ronsNe#ron cell bodies in
+an+lia
Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.nterneurons
Spinal cord
Dorsal root ganglion
#iscera
(b) Somatic path2ay
S!in
Somatic motor neuron
Dorsal rootganglion
Sensory
neuron
$utonomic
ganglion
Preganglioniciber
Postganglioniciber
S!eletal
muscle
Sensory
neuron
(a) $utonomic path2ay
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>3
Sympatheti, *i)ision
!oracol#mbardi"ision @
location of 're+an+lionic
ne#rons
Pre+an+lionic fibers lea"es'inal ner"es t!ro#+! )!ite
ramiand enter'ara"ertebral
+an+lia
Para"erterbral +an+lia andfibers t!at connect t!em
ma4e #' t!e sym'at!etic
tr#n4
Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.
#entral root
Spinal ner%es
Spinal cord
Dorsal root
Pia mater
Sympathetic
trun!
Para%ertebralsympathetic
ganglion
"rans%erse
process
#ertebral notch
(orms part o
inter%ertebral
oramen)
Body o
%ertebra
Dura
mater
$rachnoid
mater
Dorsal root
ganglion
S th ti *i i i
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>*
Sympatheti, *i)ision
Post+an+lionic fibersetend from sym'at!etic
+an+lia to "isceral or+ans
Post+an+lionic fibers#s#ally 'ass t!ro#+! +ray
ramiand ret#rn to a s'inal
ner"e before 'roceedin+ to an
effector
Ece'tion're+an+lionic fibers
to adrenal med#lla do not
syna'se )it! 'ost+an+lionic
ne#rons
Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.
Spinal cord
#entral root
Dorsal root
Sympathetic trun!Posterior horn
'ateral horn
$nterior horn
Preganglionic
neuron
Postganglionic
neuron Dorsal root
ganglion
Spinal
ner%e
#isceral eector
(intestine)
Collateral
ganglion
"o %isceral eectors
(smooth muscle
o blood %essels8arrector pili
muscles8 and
s2eat glands)
Gray
ramus
White
ramus
Dorsal branch o
spinal ner%e
#entral branch o
spinal ner%e
Para%ertebral
sympathetic
ganglion
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Parasympatheti, *i)ision
%raniosacraldi"ision @
location of 're+an+lionic
ne#rons
Can+lia are near or)it!in "ario#s or+ans
erminal +an+lia
S!ort 'ost+an+lionicfibers
%ontin#e to
s'ecific m#scles or
+lands
Pre+an+lionic fibers of t!e
!ead are incl#ded in ner"es
999, 099, and 9J
Pre+an+lionic fibers of
t!ora and abdomen are
'arts of ner"e J
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Parasympatheti, *i)isionCopyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.
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>>
Autonomi, (eurotransmitters
%!oliner+icfibersRelease acetylc!olinePre+an+lionic
sym'at!etic and
'arasym'at!etic fibers
Post+an+lionic'arasym'at!etic fibers
Adrener+icfibersRelease
nore'ine'!rineMost
'ost+an+lionic
sym'at!etic
fibers
Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.
Brain
Postganglionic iber (axon)
Preganglionic iber (axon)
Ganglion
Sympathetic neurons
$Ch 3 acetylcholine (cholinergic)
,& 3 norepinephrine (adrenergic)
$Ch
$Ch
$Ch
$Ch
$Ch $Ch
,&
,&
Cranial
parasympathetic
neurons
Sacral
parasympathetic
neurons
Collateral
ganglion
Para%ertebral
ganglion
#isceral
eectors
A,tions o Autonomi,
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A,tions o Autonomi,
(eurotransmitters
Res#lt from bindin+ to 'rotein rece'tors in t!e membrane
of effector cells
%!oliner+ic rece'tors
Bind to acetylc!oline $Ac!&M#scarinic
EcitatorySlo)
NicotinicEcitatoryRa'id
Adrener+ic rece'tors
Bind to e'ine'!rine
and nore'ine'!rineAl'!a and beta
Bot! elicit different
res'onses on "ario#seffectors
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?=
$erminating Autonomi,
(eurotransmitter A,tions
!e enyme acetylc!olinesterase ra'idly decom'oses t!e
acetylc!oline t!at c!oliner+ic fibers release(
Nore'ine'!rine from adrener+ic fibers is remo"ed by
acti"e trans'ort(
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?1
Control o Autonomi,
A,ti)ity%ontrolled lar+ely by %NS
Med#lla oblon+ata re+#lates cardiac, "asomotor andres'iratory acti"ities
Hy'ot!alam#s re+#lates "isceral f#nctions, s#c! as body
tem'erat#re, !#n+er, t!irst, and )ater and electrolyte balance
7imbic system and cerebral corte control emotional
res'onses
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?2
11+>: Liespan Changes
Brain cells be+in to die before birt!"er a"era+e lifetime, brain s!rin4s 1=FMost cell deat! occ#rs in tem'oral lobes
By a+e ?=, frontal corte !as lost !alf its ne#ronsN#mber of dendritic branc!es decreases-ecreased le"els of ne#rotransmittersadin+ memory
Slo)ed res'onses and reflees9ncreased ris4 of fallin+%!an+es in slee' 'atterns t!at res#lt in fe)er slee'in+ !o#rs
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?3
Important Points in Chapter 11:
Out,omes to e Assesse#11+1: Intro#u,tion-escribe t!e +eneral str#ct#re of t!e brain(-escribe t!e relations!i' amon+ t!e brain, brainstem, and s'inal cord(
11+2: -eninges
-escribe t!e co"erin+s of t!e brain and s'inal cord(
11+.: /entri,les an# Cererospinal lui#-escribe t!e formation and f#nction of cerebros'inal fl#id(
11+4: Spinal Cor#-escribe t!e str#ct#re of t!e s'inal cord and its maor f#nctions(
-escribe a refle arc(-escribe refle be!a"ior(
11+7: BrainName t!e maor 'arts of t!e brain and describe t!e f#nctions of eac!(-istin+#is! amon+ motor, sensory, association areas of t!e cerebral
corte(
I t t P i t i Ch t 11
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?*
Important Points in Chapter 11:
Out,omes to e Assesse#
E'lain !emis'!ere dominance(E'lain sta+es in memory stora+e(E'lain t!e f#nctions of t!e limbic system and retic#lar formation(
11+6: Peripheral (er)ous System
7ist t!e maor 'arts of t!e 'eri'!eral ner"o#s system(-escribe t!e str#ct#re of a 'eri'!eral ner"e and !o) its fibers are
classified(Name t!e cranial ner"es and list t!eir maor f#nctions(E'lain !o) s'inal ner"es are named and t!eir f#nctions
11+=: Autonomi, (er)ous System
-escribe t!e +eneral c!aracteristics of t!e a#tonomic ner"o#s system(-istin+#is! bet)een t!e sym'at!etic and t!e 'arasym'at!etic
di"isions of t!e a#tonomic ner"o#s system(-escribe a sym'at!etic and a 'arasym'at!etic ner"e 'at!)ay(E'lain !o) t!e a#tonomic ne#rotransmitters differently affect
"isceral effectors
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K#i 11
%om'lete K#i 11 no)L
Read %!a'ter 12(