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    BIOL 2064:Anatomy & Physiology 1

    Chapter 11

    Edited by Brenda Holmes

    MSN/Ed, RN

    Associate Professor

    South Aransas Community College

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    !ole"s !uman Anatomy

    an# Physiology$%elth '#ition

    Shier Butler Le%is

    Chapter

    11

    (er)ous System II: *i)isionso the (er)ous System

    Copyright The McGraw-Hill Companies, Inc. Permission required for reproduction or display.

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    11+1: Intro#u,tion

    !e central ner"o#s system $%NS& consists of t!e brain

    and s'inal cord(

    !e brainstem connects t!e brain to t!e s'inal cord(

    %omm#nication to t!e 'eri'!eral ner"o#s system $PNS&

    is by )ay of t!e s'inal cord(

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    *

    11+2: -eninges

    !e menin+esMembranes of %NSProtect t!e %NS!ree $3& layers

    -#ra mater.o#+! mot!er0eno#s sin#sesal

    Arac!noid mater.S'ider)ebli4e

    S'ace containscerebros'inal fl#id

    $%S&Pia mater

    .ait!f#l mot!er

    Enca's#lates blood"essels

    Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.

    Scalp

    Cranium

    Cerebrum

    Cerebellum

    Spinal cord

    Meninges

    Meninges

    Cerebrum

    (b)(a)

    Gray matter

    White matter

    Subarachnoid space

    Falx cerebri

    Pia mater

    Dura mater

    Bone o s!ull

    Subcutaneous tissue

    S!in

    "entorium

    cerebelli

    #ertebra

    Dural sinus (superior

    sagittal sinus)

    $rachnoid

    granulation

    $rachnoid

    mater

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    5

    -eninges o the Spinal Cor#Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.

    Spinal cord

    Spinal cord

    Pia mater

    $rachnoid mater

    Dura mater

    Dorsal root

    Dorsal root

    Spinal ner%e

    &pidural space

    (a) (b)

    #entral root

    Dorsal root

    ganglion

    "horacic

    %ertebra

    Spinal

    ner%e

    Dorsal rootganglion

    Subarachnoid

    space

    Dorsal branch

    (dorsal ramus)

    #entral branch

    (%entral ramus)

    #entral root

    &pidural

    space

    Body o

    %ertebra

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    6

    11+.: /entri,les

    an# Cererospinal lui#!ere are fo#r $*& "entricles!e "entricles are interconnected

    ca"ities )it!in cerebral !emis'!eres and

    brain stem!e "entricles are contin#o#s )it! t!e

    central canal of t!e s'inal cord!ey are filled )it! cerebros'inal fl#id

    $%S&

    !e fo#r $*& "entricles are

    7ateral "entricles $2&8no)n as t!e first and

    second "entricles!ird "entricleo#rt! "entricle

    9nter"entric#lar foramen%erebral a:#ed#ct

    'ateral %entricle

    "hird %entricle

    Fourth %entricle

    (a)

    nter%entricular

    oramen

    Cerebralaueduct

    "o central canal

    o spinal cord

    Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.

    "hird %entricle

    (b)

    Cerebral

    aueduct

    "o central canalo spinal cord

    Fourth

    %entricle

    'ateral

    %entricle

    nter%entricularoramen

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    ;

    Cererospinal lui#

    Secreted by t!e c!oroid 'le#s

    $%an yo# recall t!e s'ecific cells

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    >

    11+1 Clini,al Appli,ation

    Cererospinal lui# Pressure

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    ?

    11+4: Spinal Cor#

    Slender col#mn of ner"o#s

    tiss#e contin#o#s )it! brain

    and brainstem

    Etends do)n)ard t!ro#+!"ertebral canalBe+ins at t!e foramen

    ma+n#m and terminates at t!e

    first and second l#mbar

    "ertebrae $71/72& inters'ace

    Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.

    Brainstem

    Spinal cord

    (a) (b)

    Foramen

    magnum

    Cer%icalenlargement

    #ertebral

    canal

    'umbar

    enlargementConus

    medullaris

    Cauda

    euinaFilum

    terminale

    Conus

    medullaris

    'umbar

    enlargement

    Cer%icalenlargement

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    1=

    Stru,ture o the Spinal Cor#

    Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.

    White matter

    Gray matter

    'ateral uniculus

    Posterior uniculus

    Gray commissure

    Central canal

    (a)

    Posterior horn

    Dorsal root

    o spinal ner%e

    Dorsal root

    ganglion

    #entral root

    o spinal ner%e

    $nterior

    horn

    $nterior

    median

    issure

    Portion o

    spinal ner%e

    $nterior

    uniculus

    Posterior median

    sulcus

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    11

    un,tions o Spinal Cor#

    %enter for s'inal reflees

    %ond#it for ner"e im'#lses to and from t!e brain and

    brainstem

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    12

    ele3 Ar,s

    Reflees are a#tomatic, s#bconscio#s res'onses to stim#li

    )it!in or o#tside t!e bodySim'le refle arc $sensory @ motor&

    Most common refle arc $sensory @ association @ motor&Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.

    +eceptor

    (a)

    Sensory or

    aerent neuron

    Motor or

    eerent neuronCentral

    ,er%ous

    System

    &ector

    (muscle or gland)

    13

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    ele3 Ar,s

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    1*

    eneral Components o a

    Spinal ele3

    +eceptor

    Sensory neuron

    Motor neuron

    White matter

    Gray matter

    Spinal cord

    Dorsalnterneuron

    -

    .

    /

    0

    1

    (b)

    Cell body

    o sensory

    neuron

    &ector

    (muscle

    or gland)

    Central

    canal

    #entral

    Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.

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    15

    ele3 Beha)ior

    Eam'le is t!e knee-jerk reflexSim'le monosyna'tic refleHel's maintain an #'ri+!t 'ost#re

    Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.

    Spinal cord

    Patella

    Patellar ligamentDirection o impulse

    $xon o sensoryneuron

    Cell body o

    sensory neuron Cell body omotor neuron

    $xon o motor

    neuron

    &ector (uadriceps emorismuscle group)

    +eceptor associated 2ith

    dendrites o sensory neuron

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    ele3 Beha)iorEam'le is a withdrawal reflexPre"ents or limits tiss#e dama+e

    Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.

    nterneuron

    Spinal cord

    $xon o sensory neuron

    Cell body o sensory neuron

    Dendrite o

    sensory

    neuron

    Pain

    receptor

    in s!in

    Directiono impulse

    Cell body o

    motor neuron

    $xon omotor neuron

    &ector (lexor

    muscle contracts

    and 2ithdra2s part

    being stimulated)

    "ac!

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    1;

    ele3 Ar,

    Eam'le crossed extensor reflex%rossin+ of sensory im'#lses )it!in t!e refle center to

    'rod#ce an o''osite effect Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.

    3 Stimulation

    3 nhibition

    nterneuron

    Flexor contracts

    Sensory neuron

    4

    4

    4

    5

    5

    5

    Motor

    neurons

    &xtensorcontracts

    Flexor

    relaxes

    Motor

    neurons

    &xtensor

    relaxes

    1>

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    1>

    11+2 Clini,al Appli,ation

    5ses o ele3es

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    1?

    $ra,ts o the Spinal Cor#Ascendin+ tracts cond#ct sensory im'#lses to t!e brain-escendin+ tracts cond#ct motor im'#lses from t!e brain to

    motor ne#rons reac!in+ m#scles and +landsCopyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.

    Posterior spinocerebellar tract

    'ateral corticospinal tract

    'ateral reticulospinal tract+ubrospinal tract

    $nterior spinocerebellar tract

    'ateral spinothalamic tract

    $nterior reticulospinal tract

    Medial reticulospinal tract

    Fasciculus cuneatus

    Fasciculus gracilisDorsal column

    $nterior spinothalamic tract$nterolateral

    system

    $nterior

    corticospinaltract

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    2=

    As,en#ing $ra,ts

    Maor ascendin+ $sensory&

    s'inal cord tractsascic#l#s +racilis and

    fascic#l#s c#neat#sS'inot!alamic tracts

    7ateral and anteriorS'inocerebellar tracts

    Posterior and anterior

    Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.

    Midbrain

    Pons

    Medulla

    "halamus

    Sensory

    cortex o

    cerebrum

    Cerebrum

    (rontal

    section)

    Brainstem

    (trans%erse

    sections)

    Spinal cord

    (trans%erse section)

    Sensory ibers

    cross o%er

    Spinothalamic

    tract

    Fasciculuscuneatus

    tract

    Sensory

    impulse

    rom s!in

    temperature

    or pain

    receptors

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    *es,en#ing $ra,ts

    Maor descendin+ $motor& s'inal

    cord tracts%orticos'inal tracts

    7ateral and anteriorRetic#los'inal tracts

    7ateral, anterior and medialR#bros'inal tract

    Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.

    Midbrain

    Pons

    Brainstem

    (trans%erse

    sections)

    Spinal cord

    (trans%erse section)

    Motor cortex

    o cerebrum

    Cerebrum

    (rontal

    section)

    Corticospinal

    tract

    Medullaoblongata

    Motor ibers

    cross o%er

    Motor

    impulse tos!eletal

    muscle

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    (er)e $ra,ts o the Spinal Cor#

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    11+. Clini,al Appli,ation

    Spinal Cor# Inuries

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    2*

    11+7: Brain

    #nctions of t!e brain9nter'rets sensations-etermines 'erce'tion

    Stores memoryReasonin+Ma4es decisions%oordinates m#sc#lar mo"ements

    Re+#lates "isceral acti"ities-etermines 'ersonality

    Maor 'arts of t!e brain%erebr#m

    rontal lobes

    Parietal lobescci'ital lobesem'oral lobes9ns#la

    -ience'!alon%erebell#mBrainstem

    MidbrainPonsMed#lla oblon+ata

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    $he BrainCopyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.

    Cerebrum

    Diencephalon

    Midbrain

    Pons

    Medulla oblongata

    Spinal cord

    Cerebellum

    Fornix

    (b)

    S!ull

    Meninges

    Cerebrum

    Diencephalon

    Brainstem

    (a)

    Sulcus

    Gyrus

    Fornix

    Cerebellum

    Spinal cord

    Midbrain

    Pons

    Medulla

    oblongata

    Corpus

    callosum

    Corpuscallosum

    "rans%erse issure

    !" Martin M. #ot$er%Photo #esearchers, Inc.

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    Brain *e)elopment

    Ne#ral t#be!ree 'rimary "esicles

    orebrain

    $Prosence'!alon&

    Midbrain

    $Mesence'!alon&Hindbrain

    $R!ombence'!alon&

    i"e secondary "esicleselence'!alon-ience'!alonMesence'!alonMetence'!alonMyelence'!alon

    Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.

    Prosencephalon (orebrain)

    Mesencephalon (midbrain)

    +hombencephalon (hindbrain)

    ,eural tube

    (a)

    Diencephalon

    Mesencephalon

    Myelencephalon

    Metencephalon

    ,eural tube

    (b)

    "elencephalon

    (c)

    Diencephalon

    Midbrain

    Pons and Cerebellum

    Spinal cord

    Cerebral

    hemispheres

    Medulla

    oblongata

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    2;

    Brain *e)elopment

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    2>

    Stru,ture o the Cererum%or'#s callos#m

    %onnects cerebral

    !emis'!eres $a commiss#re&Cyri

    B#m's or con"ol#tionsS#lci

    Croo"es in +ray matter%entral s#lc#s of

    Rolando

    iss#res7on+it#dinal se'arates t!e

    cerebral !emis'!eresrans"erse se'arates

    cerebr#m from cerebell#m

    7ateral fiss#re of Syl"i#s

    Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.

    Central sulcus

    Gyrus

    Sulcus

    Frontal lobe

    'ateral sulcus

    Parietal lobe

    6ccipital lobe

    Central sulcus

    Parietal lobe

    6ccipital lobe

    (a)

    (b) (c)

    Parietal lobe

    Central sulcus

    6ccipital lobeFrontal lobe

    nsula

    "emporal lobe

    'ongitudinal

    issure

    "rans%erse

    issureCerebellar

    hemisphere

    +etracted

    temporal lobe

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    2?

    Loes o the Cererum

    i"e $5& lobes bilaterallyrontal lobeParietal lobeem'oral lobecci'ital lobe9ns#la a4aD9sland of

    Reil

    Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.

    (c)

    Parietal lobe

    Central sulcus

    6ccipital lobe

    Frontal lobe

    nsula

    +etracted

    temporal lobe

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    3=

    un,tions o the Cererum

    9nter'retin+ im'#lses9nitiatin+ "ol#ntary mo"ementsStorin+ information as memory

    Retrie"in+ stored informationReasonin+Seat of intelli+ence and 'ersonality

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    31

    un,tional egions o the

    Cereral Corte3%erebral corte

    !in layer of +ray matter t!at constit#tes t!e o#termost

    'ortion of cerebr#m

    %ontains ;5F of all ne#rons in t!e ner"o#s systemCopyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.

    Frontal eye ield

    Central sulcus

    Parietal lobe

    6ccipital lobe

    Cerebellum

    Brainstem

    nterpretation o auditory patterns

    'ateral sulcus

    $uditory area

    Sensory areas in%ol%ed 2ith

    cutaneous and other senses

    Sensory speech area( Wernic!e7s area)

    Combining

    %isual images8

    %isual recognition

    o ob9ects

    #isual area

    "emporal lobe

    Motor speech area

    (Broca7s area)

    Motor areas in%ol%ed 2ith the control

    o %oluntary muscles

    Concentration8 planning8

    problem sol%ing

    Front lobe

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    32

    un,tions o the Cereral Loes

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    33

    Sensory Areas

    8post9,entral sul,us%#taneo#s sensory areaParietal lobe9nter'rets sensations on

    s4in

    0is#al areacci'ital lobe9nter'rets "ision

    A#ditory areaem'oral lobe9nter'rets !earin+

    Sensory area for tasteNear base of t!e central s#lc#s

    Sensory area for smellArises from centers dee' )it!in

    t!e cerebr#mCopyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.

    Frontal eye ield

    Central sulcus

    Parietal lobe

    6ccipital lobe

    Cerebellum

    Brainstem

    nterpretation o auditory patterns

    'ateral sulcus

    $uditory area

    Sensory areas in%ol%ed 2ith

    cutaneous and other senses

    Sensory speech area( Wernic!e7s area)

    Combining%isual images8%isual recognition

    o ob9ects

    #isual area

    "emporal lobe

    Motor speech area

    (Broca7s area)

    Motor areas in%ol%ed 2ith the controlo %oluntary muscles

    Concentration8 planning8

    problem sol%ing

    Front lobe

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    3*

    Sensory AreasCopyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.

    Parietal lobe

    Sensory area

    Central sulcus

    Motor area

    Frontal lobe

    S2allo2ing

    Forearm

    $rmPel%is

    "high

    'eg

    'ips

    Forearm $rm,ec! Pel%is

    "high

    'eg

    Genitals

    (a) Motor area (b) Sensory area

    'ongitudinalissure

    Sali%ation#ocali:ation

    Mastication

    Facial

    expression

    "humb8

    ingers8

    and hand

    "run!

    Foot and

    toes

    "ongue andpharynx

    "eeth andgums

    ;pper

    ace

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    Asso,iation Areas

    Re+ions t!at are not 'rimary motor or 'rimary sensory areasGides'read t!ro#+!o#t t!e cerebral corteAnalye and inter'ret sensory e'eriencesPro"ide memory, reasonin+, "erbaliation, #d+ment, emotions

    Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.

    Frontal eye ield

    Central sulcus

    Parietal lobe

    6ccipital lobe

    Cerebellum

    Brainstem

    nterpretation o auditory patterns

    'ateral sulcus

    $uditory area

    Sensory areas in%ol%ed 2ith

    cutaneous and other senses

    Sensory speech area

    ( Wernic!e7s area)

    Combining

    %isual images8

    %isual recognition

    o ob9ects

    #isual area

    "emporal lobe

    Motor speech area

    (Broca7s area)

    Motor areas in%ol%ed 2ith the control

    o %oluntary muscles

    Concentration8 planning8

    problem sol%ing

    Front lobe

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    Asso,iation Areas

    rontal lobe association areas%oncentratin+Plannin+%om'le 'roblem sol"in+

    Parietal lobe association areasInderstandin+ s'eec!%!oosin+ )ords to e'ress

    t!o#+!t

    em'oral lobe association areas9nter'ret com'le sensory

    e'eriencesStore memories of "is#al scenes,

    m#sic, and com'le 'atterns

    cci'ital lobe association areasAnalye and combine "is#al

    ima+es )it! ot!er sensory

    e'eriences

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    3;

    -otor Areas

    8pre9,entral sul,usPrimary motor areas

    rontal lobes%ontrol "ol#ntary m#scles

    Brocas areaAnterior to 'rimary motor

    corteIs#ally in left !emis'!ere%ontrols m#scles needed for

    s'eec!

    rontal eye fieldAbo"e Brocas area%ontrols "ol#ntary mo"ements

    of eyes and eyelids

    Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.

    Frontal eye ield

    Central sulcus

    Parietal lobe

    6ccipital lobe

    Cerebellum

    Brainstem

    nterpretation o auditory patterns

    'ateral sulcus

    $uditory area

    Sensory areas in%ol%ed 2ith

    cutaneous and other senses

    Sensory speech area

    ( Wernic!e7s area)

    Combining

    %isual images8

    %isual recognition

    o ob9ects

    #isual area

    "emporal lobe

    Motor speech area

    (Broca7s area)

    Motor areas in%ol%ed 2ith the control

    o %oluntary muscles

    Concentration8 planning8

    problem sol%ing

    Front lobe

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    3>

    -otor AreasCopyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.

    Parietal lobe

    Sensory area

    Central sulcus

    Motor area

    Frontal lobe

    S2allo2ing

    Forearm

    $rmPel%is

    "high

    'eg

    'ips

    Forearm $rm,ec! Pel%is

    "high

    'eg

    Genitals

    (a) Motor area (b) Sensory area

    'ongitudinalissure

    Sali%ation#ocali:ation

    Mastication

    Facial

    expression

    "humb8

    ingers8

    and hand

    "run!

    Foot and

    toes

    "ongue andpharynx

    "eeth andgums

    ;pper

    ace

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    3?

    !emisphere *ominan,e

    !e left !emis'!ere is dominant in most indi"id#als

    -ominant !emis'!ere controls

    S'eec!Gritin+Readin+0erbal s4illsAnalytical s4ills%om'#tational s4ills

    Nondominant !emis'!ere controls

    Non"erbal tas4sMotor tas4sInderstandin+ and inter'retin+

    m#sical and "is#al 'atternsPro"ides emotional and int#iti"e

    t!o#+!t 'rocesses

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    *=

    -emory

    S!ort term memoryGor4in+ memory%losed ne#ronal circ#it

    %irc#it is stim#lated o"er ando"erG!en im'#lse flo) ceases,

    memory does also #nless it

    enters lon+term memory "ia

    memory consolidation

    7on+ term memory%!an+es str#ct#re or

    f#nction of ne#rons

    En!ances syna'tictransmission

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    *1

    11+4 Clini,al Appli,ation

    $raumati, Brain Inury

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    *2

    Basal (u,lei

    Masses of +ray matter-ee' )it!in cerebral

    !emis'!eres

    %a#date n#cle#s,'#tamen, and +lob#s

    'allid#sProd#ce do'amine%ontrol certain m#sc#lar

    acti"itiesPrimarily by

    in!ibitin+ motor

    f#nctions

    Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.

    "halamus

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    *3

    *ien,ephalon

    Bet)een cerebral !emis'!eres and abo"e t!e brainstemS#rro#nds t!e t!ird "entricle

    !alam#s

    E'it!alam#sHy'ot!alam#s'tic tracts'tic c!iasm

    9nf#ndib#l#mPosterior 'it#itaryMammillary bodiesPineal +land

    Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.

    Pyramidal tract

    Pons

    6ptic ner%e6ptic chiasma

    "halamus

    Spinal cord

    Pituitary gland

    Pineal gland

    6ptic tract

    Mammillary body

    (a) (b)

    6li%e

    Corpora uadrigemina

    Cerebral

    peduncles

    Superior

    colliculus

    neriorcolliculus

    "hird

    %entricle

    Fourth%entricle

    Cerebellarpeduncles

    Medulla

    oblongata

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    **

    *ien,ephalon

    !alam#sCate)ay for sensory im'#lses !eadin+ to cerebral corteRecei"es all sensory im'#lses $ece't smell&

    %!annels im'#lses to a''ro'riate 'art of cerebral corte forinter'retation

    Hy'ot!alam#sMaintains !omeostasis by re+#latin+ "isceral acti"ities7in4s ner"o#s and endocrine systems $!ence some say t!e

    ne#roendocrine system

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    *5

    *ien,ephalon

    %onsists of

    Portions of frontal lobePortions of tem'oral lobeHy'ot!alam#s!alam#sBasal n#cleit!er dee' n#clei

    #nctions

    %ontrols emotionsProd#ces feelin+s9nter'rets sensory im'#lses

    $he Limi, System

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    *6

    11+7 Clini,al Appli,ation

    Parinson *isease

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    *;

    Brainstem

    !ree 'arts

    1( Midbrain

    2( Pons

    3( Med#lla blon+ata

    Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.

    Spinal cord

    "halamus

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    *>

    -i#rain

    Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.

    Pyramidal tract

    Pons

    6ptic ner%e6ptic chiasma

    "halamus

    Spinal cord

    Pituitary gland

    Pineal gland

    6ptic tract

    Mammillary body

    (a) (b)

    6li%e

    Corpora uadrigemina

    Cerebral

    peduncles

    Superiorcolliculus

    nerior

    colliculus

    "hird%entricle

    Fourth

    %entricle

    Cerebellarpeduncles

    Medulla

    oblongata

    Bet)een dience'!alon and 'ons%ontains b#ndles of fibers t!at

    oin lo)er 'arts of brainstem and

    s'inal cord )it! !i+!er 'art of

    brain

    %erebral a:#ed#ct%erebral 'ed#ncles $b#ndles of

    ner"e fibers&%or'ora :#adri+emina $centers

    for "is#al and a#ditory reflees&

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    *?

    Pons

    Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.

    Pyramidal tract

    Pons

    6ptic ner%e6ptic chiasma

    "halamus

    Spinal cord

    Pituitary gland

    Pineal gland

    6ptic tract

    Mammillary body

    (a) (b)

    6li%e

    Corpora uadrigemina

    Cerebralpeduncles

    Superior

    colliculus

    neriorcolliculus

    "hird

    %entricle

    Fourth%entricle

    Cerebellar

    peduncles

    Medullaoblongata

    Ro#nded b#l+e on #nderside of

    brainstemBet)een med#lla oblon+ata and

    midbrainHel's re+#late rate and

    de't! of breat!in+Relays ner"e im'#lses to and from

    med#lla oblon+ata and cerebell#m

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    5=

    -e#ulla Olongata

    Enlar+ed contin#ation of

    s'inal cord%ond#cts ascendin+ and

    descendin+ im'#lses bet)een

    brain and s'inal cord%ontains cardiac,

    "asomotor, and res'iratory

    control centers%ontains "ario#s non"ital

    refle control centers

    $co#+!in+, sneein+,

    s)allo)in+, and "omitin+&

    Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.

    Pyramidal tract

    Pons

    6ptic ner%e6ptic chiasma

    "halamus

    Spinal cord

    Pituitary gland

    Pineal gland

    6ptic tract

    Mammillary body

    (a) (b)

    6li%e

    Corpora uadrigemina

    Cerebralpeduncles

    Superior

    colliculus

    neriorcolliculus

    "hird

    %entricle

    Fourth%entricle

    Cerebellar

    peduncles

    Medullaoblongata

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    51

    eti,ular ormation

    %om'le net)or4 of ner"e

    fibers scattered t!ro#+!o#t t!e

    brain stemEtends into t!e dience'!alon

    %onnects to centers of!y'ot!alam#s, basal n#clei,

    cerebell#m, and cerebr#milters incomin+ sensory

    informationAro#ses cerebral corte intostate of )a4ef#lness

    Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.

    Spinal cord

    "halamus

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    52

    $ypes o Sleep

    Slo) )a"eNonREM slee'Person is tired

    -ecreasin+ acti"ity ofretic#lar systemRestf#l-reamlessRed#ced blood 'ress#re and

    res'iratory rateRan+es from li+!t to !ea"yAlternates )it! REM slee'

    Ra'id Eye Mo"ement $REM&Paradoical slee'Some areas of brain acti"e

    Heart and res'iratory ratesirre+#lar-reamin+ occ#rs

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    53

    Cereellum

    9nferior to occi'ital lobesPosterior to 'ons and med#lla

    oblon+ata)o !emis'!eres0ermis connects !emis'!eres

    %erebellar corte $+ray matter&Arbor "itae $)!ite matter&%erebellar 'ed#ncles $ner"e fiber

    tracts&-entate n#cle#s $lar+est n#cle#s in

    cerebell#m&9nte+rates sensory information

    concernin+ 'osition of body 'arts%oordinates s4eletal m#scle acti"ityMaintains 'ost#re

    Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.

    "halamus

    Superior peduncle

    Middle peduncle

    nerior peduncle

    Pons

    Medulla oblongata

    Cerebellum

    Corpus callosum

    'ongitudinal

    issure

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    5*

    -aor Parts o the Brain

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    56

    11+6: Peripheral (er)ous System

    %ranial ner"esarisin+ from t!e brainSomatic fibers connectin+ to t!e s4in and s4eletal m#sclesA#tonomic fibers connectin+ to "iscera

    S'inal ner"esarisin+ from t!e s'inal cordSomatic fibers connectin+ to t!e s4in and s4eletal m#sclesA#tonomic fibers connectin+ to "iscera

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    5;

    (er)ous System Su#i)isions

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    5>

    Stru,ture o a Peripheral (er)eCopyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.

    Peripheral ner%e

    &pineurium

    $xon

    ,eurilemma

    Myelin sheath

    Sch2ann cell

    ,ode o +an%ier

    &ndoneurium

    Perineurium

    Fascicle

    Sensory receptor

    Motor neuron

    ending

    ( # ( i

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    5?

    (er)e an# (er)e ier

    Classii,ation

    Sensory ner"es%ond#ct im'#lses into brain or s'inal cord

    Motor ner"es%ond#ct im'#lses to m#scles or +lands

    Mied $bot! sensory and motor& ner"es%ontain bot! sensory ner"e fibers and motor ner"e fibers

    Most ner"es are mied ner"esA77 s'inal ner"es are mied ner"es $ece't t!e first 'air&

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    6=

    (er)e ier Classii,ation

    Ceneral somatic efferent $CSE& fibers%arry motor im'#lses from %NS to

    s4eletal m#scles

    Ceneral "isceral efferent $C0E& fibers%arry motor im'#lses a)ay from

    %NS to smoot! m#scles and +lands

    Ceneral somatic afferent $CSA& fibers%arry sensory im'#lses to %NS from

    s4in and s4eletal m#scles

    Ceneral "isceral afferent $C0A& fibers%arry sensory im'#lses to %NS from

    blood "essels and internal or+ans

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    62

    Cranial (er)esCopyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.

    6lactory bulb

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    63

    Cranial (er)es

    Remember

    %ranial ner"es are desi+nated D% N

    %ranial ner"es are desi+nated )it! Roman n#merals$9 @ J99&

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    6*

    Cranial (er)es I an# II

    lfactory ner"e $%N 9&Sensory ner"eibers transmit im'#lses

    associated )it! smell

    'tic ner"e $%N 99&Sensory ner"eibers transmit im'#lses

    associated )it! "ision

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    65

    Cranial (er)es III an# I/

    roc!lear ner"e $%N 90&Primarily motor ner"eMotor im'#lses to m#scles

    t!at mo"e t!e eyesSome sensory

    Pro'rioce'tors

    c#lomotor ner"e $%N 999&Primarily motor ner"eMotor im'#lses to m#scles

    t!atRaise eyelidsMo"e t!e eyesoc#s lensAd#st li+!t enterin+ eye

    Some sensoryPro'rioce'tors

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    66

    Cranial (er)e /

    ri+eminal ner"e $%N 0&Mied ner"e.!ree $3& sisters$1& '!t!almic di"ision

    Sensory from s#rface of eyes,

    tear +lands, scal', fore!ead,and #''er eyelids

    $2& Maillary di"isionSensory from #''er teet!,

    #''er +#m, #''er li', 'alate,

    and s4in of face

    $3& Mandib#lar di"isionSensory from scal', s4in of

    a), lo)er teet!, lo)er +#m,

    and lo)er li'

    Motor to m#scles of

    mastication and m#scles infloor of mo#t!

    Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.

    'acrimal ner%e

    &ye

    Maxilla

    Mandible

    'acrimal

    gland

    nraorbital

    ner%e

    "ongue

    Mental

    ner%e

    6phthalmic

    di%ision

    Maxillary

    di%ision

    Mandibular

    di%ision

    'ingual

    ner%e

    nerior

    al%eolar

    ner%e

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    6;

    Cranial (er)es /I an# /II

    Abd#cens ner"e $%N 09&Primarily motor ner"eMotor im'#lses to m#scles

    t!at mo"e t!e eyesSome sensory

    Pro'rioce'tors

    acial ner"e $%N 099&Mied ner"eSensory from taste rece'torsMotor to m#scles of facial

    e'ression, tear +lands, andsali"ary +lands

    Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.

    >ygomatic ner%e

    Buccal ner%e

    Facial ner%e

    Mandibular ner%e

    Cer%ical ner%e

    "emporal ner%e

    Posterior auricular

    ner%e

    Parotid sali%ary

    gland

    6>

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    6>

    Cranial (er)es /III an# I cer"ical ner"es

    $%1 to %>&12 t!oracic ner"es

    $1 to 12&5 l#mbar ner"es

    $71 to 75&5 sacral ner"es$S1 to S5&

    1 coccy+eal ner"e$%o or %c&

    Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.

    Cauda euina

    C1C0C/C-C.C@CAC"1

    "0

    "/

    "-

    ".

    "@

    "A

    "

    "

    "1

    "11

    "10

    '1

    '0

    '/

    '-

    '.

    S0S/

    S-

    S1

    S.Co

    Posterior%ie2

    Cer%ical

    ner%es

    "horacic

    ner%es

    'umbar

    ner%es

    Sacral

    ner%es

    Coccygeal

    ner%e

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    ;3

    Spinal (er)es

    -orsal root $a4a'osteriorroot&

    Sensory rootAons of sensory

    ne#rons are in t!e dorsal

    root +an+lion-orsal root +an+lion

    A4a -RC%ell bodies of sensory

    ne#rons )!ose aons

    cond#ct im'#lses in)ardfrom 'eri'!eral body 'arts

    Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.

    'ateral horn

    #entral root(a)

    (b)

    Dorsal root

    Dorsal root

    Spinal ner%e

    Dorsal root

    ganglion

    Posteriormedian sulcus

    Posterior

    horn

    $nterior

    horn

    Central

    canal

    $nteriormedian

    issure

    Dorsal branch

    o spinal ner%e

    #entral branch

    o spinal ner%e

    #isceral brancho spinal ner%e

    Para%ertebral

    ganglion

    #entral branch

    o spinal ner%e (%entral ramus)

    Dorsal branch

    o spinal ner%e (dorsal ramus)

    Para%ertebral

    ganglion#isceral branch

    o spinal ner%e

    #entral root

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    ;*

    *ermatome

    An area of s4in t!at t!e sensory ner"e fibers of a 'artic#lars'inal ner"e inner"ate

    C0C/

    C-

    C.

    C@

    "1

    C@

    CA

    S0

    S/

    C

    '1

    '0

    '/

    '-

    '.

    "10

    "1

    S1

    (a) (b)

    S.C

    S-S/

    S0

    S1

    '.

    '-

    '/

    '0

    '1

    '.

    '1

    C"1

    "10

    CAC@

    C.C-

    C/

    C0

    Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction o r display.

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    ;5

    Spinal (er)es

    0entral root $a4aanterior root&Motor rootAons of motor ne#rons

    )!ose cell bodies are in t!e

    s'inal cord

    S'inal ner"eInion of "entral root

    and dorsal rootsHence )e no) !a"e a

    .mied ner"e

    Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.

    'ateral horn

    #entral root(a)

    (b)

    Dorsal root

    Dorsal root

    Spinal ner%e

    Dorsal root

    ganglion

    Posteriormedian sulcus

    Posterior

    horn

    $nterior

    horn

    Central

    canal

    $nteriormedian

    issure

    Dorsal branch

    o spinal ner%e

    #entral branch

    o spinal ner%e

    #isceral brancho spinal ner%e

    Para%ertebral

    ganglion

    #entral branch

    o spinal ner%e (%entral ramus)

    Dorsal branch

    o spinal ner%e (dorsal ramus)

    Para%ertebral

    ganglion#isceral branch

    o spinal ner%e

    #entral root

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    ;6

    (er)e Ple3uses

    Ner"e 'le#s%om'le net)or4s formed by anterior branc!es of s'inal ner"es!e fibers of "ario#s s'inal ner"es are sorted and recombined!ere are t!ree $3& ner"e 'le#ses

    $1& %er"ical 'le#sormed by anterior branc!es of %1%* s'inal ner"es7ies dee' in t!e nec4S#''ly to m#scles and s4in of t!e nec4%3%*%5 ner"e roots contrib#te to '!renic ner"es bilaterally

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    ;;

    Bra,hial Ple3us

    $2& Brac!ial 'le#sormed by anterior branc!es %5

    17ies dee' )it!in s!o#lders!ere are fi"e $5& branc!es1( M#sc#loc#taneo#s ner"e

    S#''ly m#scles of anterior arms

    and s4in of forearms

    2( Ilnar and 3( Median ner"esS#''ly m#scles of forearms and

    !ands

    S#''ly s4in of !ands*( Radial ner"eS#''ly 'osterior m#scles of arms

    and s4in of forearms and !ands

    5( Aillary ner"eS#''ly m#scles and s4in of

    anterior, lateral, and 'osterior arms

    Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.

    Musculocutaneous nE

    Musculocutaneous nE

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    ;>

    Lumosa,ral Ple3us

    $3& 7#mbosacral 'le#sormed by t!e anterior branc!es

    of 71S5 roots%an be a l#mbar $7175& 'le#s

    and a sacral $S1S5& 'le#s

    Etends from l#mbar re+ion into'el"ic ca"itybt#rator ner"e

    S#''ly motor im'#lses to

    add#ctors of t!i+!s

    emoral ner"e

    S#''ly motor im'#lses tom#scles of anterior t!i+! and

    sensory im'#lses from s4in of

    t!i+!s and le+s

    Sciatic ner"eS#''ly m#scles and s4in of

    t!i+!s, le+s and feet

    Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.

    Sciatic nE

    Saphenous nE

    Femoral nE

    6bturator nE

    "ibial nE

    Pudendal nE

    (b) (c)(a)

    Femoral nE

    6bturator nE

    Pudendal nE

    Sciatic nE

    '1

    '0

    '/

    '-

    '.

    S1

    S0

    S/

    S-

    S.

    #entralrami

    $nterior

    di%isions

    Posteriordi%isions

    'ateralemoral

    cutaneous nE

    Superior

    gluteal nE

    nerior

    gluteal nE

    Superior

    gluteal nE

    nerior

    gluteal nE

    Sacralplexus

    Commonibular

    (peroneal) nE

    Posterior

    cutaneous nE

    Common

    ibular

    (peroneal) nE"ibial nE

    Pl

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    ;?

    Ple3uses

    C1C0C/C-

    C.C@CAC"1

    "0

    "/

    "-

    ".

    "@

    "

    "

    "1

    "11

    "10

    '1

    '0

    '/

    '-

    '.

    S0S/S-S.

    Co

    Posterior %ie2

    Cer%ical plexus(C15C-)

    'umbosacral plexus("105S.)

    Sciatic ner%e

    Brachial plexus(C.5"1)

    6bturator ner%e

    Phrenic ner%e

    ;lnar ner%e

    Median ner%e

    +adial ner%e

    $xillary ner%e

    "A

    S1

    Cauda euina

    Musculocutaneousner%e

    Femoralner%e

    ntercostalner%es

    Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.

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    >=

    11+= Clini,al Appli,ation

    Spinal (er)e Inuries

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    >1

    11+=: Autonomi, (er)ous System

    #nctions )it!o#t conscio#s effort%ontrols "isceral acti"itiesRe+#lates smoot! m#scle, cardiac m#scle, and +lands

    Efferent fibers ty'ically lead to +an+lia o#tside of t!e %NS

    )o a#tonomic di"isions re+#lateSym'at!etic di"ision $s'eeds #'&

    Pre'ares body for Dfi+!t or fli+!t sit#ations

    Parasym'at!etic di"ision $slo)s do)n&Pre'ares body for Drestin+ and di+estin+ acti"ities

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    >2

    Autonomi, (er)e iers

    All of t!e ne#rons are

    motor $efferent&

    Pre+an+lionicfibersAons of 're+an+lionic

    ne#ronsNe#ron cell bodies in

    %NS

    Post+an+lionicfibersAons of 'ost+an+lionic

    ne#ronsNe#ron cell bodies in

    +an+lia

    Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.nterneurons

    Spinal cord

    Dorsal root ganglion

    #iscera

    (b) Somatic path2ay

    S!in

    Somatic motor neuron

    Dorsal rootganglion

    Sensory

    neuron

    $utonomic

    ganglion

    Preganglioniciber

    Postganglioniciber

    S!eletal

    muscle

    Sensory

    neuron

    (a) $utonomic path2ay

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    >3

    Sympatheti, *i)ision

    !oracol#mbardi"ision @

    location of 're+an+lionic

    ne#rons

    Pre+an+lionic fibers lea"es'inal ner"es t!ro#+! )!ite

    ramiand enter'ara"ertebral

    +an+lia

    Para"erterbral +an+lia andfibers t!at connect t!em

    ma4e #' t!e sym'at!etic

    tr#n4

    Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.

    #entral root

    Spinal ner%es

    Spinal cord

    Dorsal root

    Pia mater

    Sympathetic

    trun!

    Para%ertebralsympathetic

    ganglion

    "rans%erse

    process

    #ertebral notch

    (orms part o

    inter%ertebral

    oramen)

    Body o

    %ertebra

    Dura

    mater

    $rachnoid

    mater

    Dorsal root

    ganglion

    S th ti *i i i

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    >*

    Sympatheti, *i)ision

    Post+an+lionic fibersetend from sym'at!etic

    +an+lia to "isceral or+ans

    Post+an+lionic fibers#s#ally 'ass t!ro#+! +ray

    ramiand ret#rn to a s'inal

    ner"e before 'roceedin+ to an

    effector

    Ece'tion're+an+lionic fibers

    to adrenal med#lla do not

    syna'se )it! 'ost+an+lionic

    ne#rons

    Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.

    Spinal cord

    #entral root

    Dorsal root

    Sympathetic trun!Posterior horn

    'ateral horn

    $nterior horn

    Preganglionic

    neuron

    Postganglionic

    neuron Dorsal root

    ganglion

    Spinal

    ner%e

    #isceral eector

    (intestine)

    Collateral

    ganglion

    "o %isceral eectors

    (smooth muscle

    o blood %essels8arrector pili

    muscles8 and

    s2eat glands)

    Gray

    ramus

    White

    ramus

    Dorsal branch o

    spinal ner%e

    #entral branch o

    spinal ner%e

    Para%ertebral

    sympathetic

    ganglion

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    i i i i

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    >6

    Parasympatheti, *i)ision

    %raniosacraldi"ision @

    location of 're+an+lionic

    ne#rons

    Can+lia are near or)it!in "ario#s or+ans

    erminal +an+lia

    S!ort 'ost+an+lionicfibers

    %ontin#e to

    s'ecific m#scles or

    +lands

    Pre+an+lionic fibers of t!e

    !ead are incl#ded in ner"es

    999, 099, and 9J

    Pre+an+lionic fibers of

    t!ora and abdomen are

    'arts of ner"e J

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    >;

    Parasympatheti, *i)isionCopyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.

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    >>

    Autonomi, (eurotransmitters

    %!oliner+icfibersRelease acetylc!olinePre+an+lionic

    sym'at!etic and

    'arasym'at!etic fibers

    Post+an+lionic'arasym'at!etic fibers

    Adrener+icfibersRelease

    nore'ine'!rineMost

    'ost+an+lionic

    sym'at!etic

    fibers

    Copyright The McGraw-Hill Companies, Inc. Permission required or reproduction or display.

    Brain

    Postganglionic iber (axon)

    Preganglionic iber (axon)

    Ganglion

    Sympathetic neurons

    $Ch 3 acetylcholine (cholinergic)

    ,& 3 norepinephrine (adrenergic)

    $Ch

    $Ch

    $Ch

    $Ch

    $Ch $Ch

    ,&

    ,&

    Cranial

    parasympathetic

    neurons

    Sacral

    parasympathetic

    neurons

    Collateral

    ganglion

    Para%ertebral

    ganglion

    #isceral

    eectors

    A,tions o Autonomi,

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    >?

    A,tions o Autonomi,

    (eurotransmitters

    Res#lt from bindin+ to 'rotein rece'tors in t!e membrane

    of effector cells

    %!oliner+ic rece'tors

    Bind to acetylc!oline $Ac!&M#scarinic

    EcitatorySlo)

    NicotinicEcitatoryRa'id

    Adrener+ic rece'tors

    Bind to e'ine'!rine

    and nore'ine'!rineAl'!a and beta

    Bot! elicit different

    res'onses on "ario#seffectors

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    ?=

    $erminating Autonomi,

    (eurotransmitter A,tions

    !e enyme acetylc!olinesterase ra'idly decom'oses t!e

    acetylc!oline t!at c!oliner+ic fibers release(

    Nore'ine'!rine from adrener+ic fibers is remo"ed by

    acti"e trans'ort(

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    ?1

    Control o Autonomi,

    A,ti)ity%ontrolled lar+ely by %NS

    Med#lla oblon+ata re+#lates cardiac, "asomotor andres'iratory acti"ities

    Hy'ot!alam#s re+#lates "isceral f#nctions, s#c! as body

    tem'erat#re, !#n+er, t!irst, and )ater and electrolyte balance

    7imbic system and cerebral corte control emotional

    res'onses

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    ?2

    11+>: Liespan Changes

    Brain cells be+in to die before birt!"er a"era+e lifetime, brain s!rin4s 1=FMost cell deat! occ#rs in tem'oral lobes

    By a+e ?=, frontal corte !as lost !alf its ne#ronsN#mber of dendritic branc!es decreases-ecreased le"els of ne#rotransmittersadin+ memory

    Slo)ed res'onses and reflees9ncreased ris4 of fallin+%!an+es in slee' 'atterns t!at res#lt in fe)er slee'in+ !o#rs

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    ?3

    Important Points in Chapter 11:

    Out,omes to e Assesse#11+1: Intro#u,tion-escribe t!e +eneral str#ct#re of t!e brain(-escribe t!e relations!i' amon+ t!e brain, brainstem, and s'inal cord(

    11+2: -eninges

    -escribe t!e co"erin+s of t!e brain and s'inal cord(

    11+.: /entri,les an# Cererospinal lui#-escribe t!e formation and f#nction of cerebros'inal fl#id(

    11+4: Spinal Cor#-escribe t!e str#ct#re of t!e s'inal cord and its maor f#nctions(

    -escribe a refle arc(-escribe refle be!a"ior(

    11+7: BrainName t!e maor 'arts of t!e brain and describe t!e f#nctions of eac!(-istin+#is! amon+ motor, sensory, association areas of t!e cerebral

    corte(

    I t t P i t i Ch t 11

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    ?*

    Important Points in Chapter 11:

    Out,omes to e Assesse#

    E'lain !emis'!ere dominance(E'lain sta+es in memory stora+e(E'lain t!e f#nctions of t!e limbic system and retic#lar formation(

    11+6: Peripheral (er)ous System

    7ist t!e maor 'arts of t!e 'eri'!eral ner"o#s system(-escribe t!e str#ct#re of a 'eri'!eral ner"e and !o) its fibers are

    classified(Name t!e cranial ner"es and list t!eir maor f#nctions(E'lain !o) s'inal ner"es are named and t!eir f#nctions

    11+=: Autonomi, (er)ous System

    -escribe t!e +eneral c!aracteristics of t!e a#tonomic ner"o#s system(-istin+#is! bet)een t!e sym'at!etic and t!e 'arasym'at!etic

    di"isions of t!e a#tonomic ner"o#s system(-escribe a sym'at!etic and a 'arasym'at!etic ner"e 'at!)ay(E'lain !o) t!e a#tonomic ne#rotransmitters differently affect

    "isceral effectors

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    K#i 11

    %om'lete K#i 11 no)L

    Read %!a'ter 12(