cervical ribs in human fetuses

Letter to the Editor Cervical Ribs in Human Fetuses To the Editor: With respect to the letter by Dr. Seller [1998] con- cerning our article “Cervical Ribs in Fetuses With Ull- rich-Turner syndrome”, I should like to respond as fol- lows. The observation of cervical ribs in fetuses with Ull- rich-Turner syndrome has, since publication in this journal, been followed up by a new and extended study, carried out in collaboration with Dr. J.W. Keeling in Edinburgh. This new investigation was completed in 1997 and is now in press in an international journal. Its purposes was to test the usefulness of the published observation of cervical ribs in hydropic fetuses with 45,X karyotype who had not previously been examined specifically for cervical ribs. Anteroposterior radiographs from 36 hydropic fetuses were examined by one author without knowledge of fetal karyotype or pathological findings. Cervical ribs were demonstrated in 15 of 16 45,X fetuses and one of eight with trisomy 21. Cervical ribs were not seen in the remaining fetuses. REFERENCES Seller MJ (1998): Cervical Ribs in Fetuses With UTS. Am J Med Genet 78:397. Inger Kjær* Department of Orthodontics School of Dentistry Faculty of Health Sciences University of Copenhagen Copenhagen, Denmark *Correspondence to: Dr. Inger Kjær, Dept. of Orthodontics, School of Dentistry, Faculty of Health Sciences, University of Copenhagen, Norre Alle ´ 20, DK-2200, Copenhagen N, Denmark. Received 12 January 1998; Accepted 7 April 1998 American Journal of Medical Genetics 78:392 (1998) © 1998 Wiley-Liss, Inc.

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Letter to the Editor

Cervical Ribs in Human Fetuses

To the Editor:

With respect to the letter by Dr. Seller [1998] con-cerning our article “Cervical Ribs in Fetuses With Ull-rich-Turner syndrome”, I should like to respond as fol-lows.

The observation of cervical ribs in fetuses with Ull-rich-Turner syndrome has, since publication in thisjournal, been followed up by a new and extended study,carried out in collaboration with Dr. J.W. Keeling inEdinburgh. This new investigation was completed in1997 and is now in press in an international journal.Its purposes was to test the usefulness of the publishedobservation of cervical ribs in hydropic fetuses with45,X karyotype who had not previously been examinedspecifically for cervical ribs.

Anteroposterior radiographs from 36 hydropic fe-

tuses were examined by one author without knowledgeof fetal karyotype or pathological findings. Cervicalribs were demonstrated in 15 of 16 45,X fetuses andone of eight with trisomy 21. Cervical ribs were notseen in the remaining fetuses.

REFERENCES

Seller MJ (1998): Cervical Ribs in Fetuses With UTS. Am J Med Genet78:397.

Inger Kjær*Department of OrthodonticsSchool of DentistryFaculty of Health SciencesUniversity of CopenhagenCopenhagen, Denmark

*Correspondence to: Dr. Inger Kjær, Dept. of Orthodontics,School of Dentistry, Faculty of Health Sciences, University ofCopenhagen, Norre Alle 20, DK-2200, Copenhagen N, Denmark.

Received 12 January 1998; Accepted 7 April 1998

American Journal of Medical Genetics 78:392 (1998)

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