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Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved. 1 Career Opportunities in the Life Sciences Toby Beth Freedman, Ph.D. February 28 th , 2008 Career Opportunities in Biotechnology and Drug Development

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Page 1: Career Opportunities in the Life Sciences€¦ · Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved. 18 Many Areas to Consider Table

Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved. 1

Career Opportunities in the Life Sciences

Toby Beth Freedman, Ph.D.February 28th, 2008

Career Opportunities in Biotechnologyand Drug Development

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The Experiment

• A comprehensive, systematic assessment of careers in the biotechnology, pharmaceutical and medical device industries

• Not hypothesis driven, discovery based research

• Resource guide for career planning

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Goals: Get on the Right Track

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Goals: Be Sure To Enjoy a Job

If you are doing what you love, then it’s not really “work”

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Methods

• 200+ interviews• 1-2 hour telephone interviews• Mostly VPs, most had Ph.D. or MD or other type

of advanced degree• About 10 interviews per chapter• Data was compiled, analyzed and summarized • Interviewees reviewed draft chapters• Project took three years to complete

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Results: So Many Careers To Choose!Discovery ResearchRecruiting

LawVenture Capital & Banking

Management Consulting

Bio IT

Quality

Operations & Manufacturing

Business Development

Corporate Communications

Product Support

Sales

Marketing

Medical Affairs

Regulatory Affairs

Clinical Development

Project Management

Bio/Pharmaceutical Product Development

Preclinical Research

R&DServices

Operations

Commercial Operations

Page 7: Career Opportunities in the Life Sciences€¦ · Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved. 18 Many Areas to Consider Table

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Careers in ResearchDiscovery ResearchDiscovery ResearchRecruiting

LawVenture Capital & Banking

Management Consulting

Bio IT

Quality

Operations & Manufacturing

Business Development

Corporate Communications

Product Support

Sales

Marketing

Medical Affairs

Regulatory Affairs

Clinical Development

Project Management

Bio/Pharmaceutical Product Development

Preclinical Research

R&DServices

Operations

Commercial Operations

Page 8: Career Opportunities in the Life Sciences€¦ · Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved. 18 Many Areas to Consider Table

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Careers for ChemistsDiscovery ResearchDiscovery ResearchRecruiting

LawVenture Capital & Banking

Management Consulting

Bio IT

QualityQuality

Operations & Manufacturing

Business Development

Corporate Communications

Product Support

Sales

Marketing

Medical Affairs

Regulatory Affairs

Clinical Development

Project Management

Bio/Pharmaceutical Product Development

Bio/Pharmaceutical Product Development

Preclinical ResearchPreclinical Research

R&DServices

Operations

Commercial Operations

Page 9: Career Opportunities in the Life Sciences€¦ · Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved. 18 Many Areas to Consider Table

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Careers for MDsDiscovery ResearchRecruiting

LawVenture Capital & Banking

Venture Capital & Banking

Management ConsultingManagement Consulting

Bio IT

Quality

Operations & Manufacturing

Business Development

Corporate Communications

Product Support

Sales

Marketing

Medical AffairsMedical Affairs

Regulatory Affairs

Clinical DevelopmentClinical Development

Project Management

Bio/Pharmaceutical Product Development

Preclinical Research

R&DServices

Operations

Commercial Operations

Page 10: Career Opportunities in the Life Sciences€¦ · Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved. 18 Many Areas to Consider Table

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Careers for MBAsDiscovery ResearchRecruiting

LawVenture Capital & Banking

Management Consulting

Bio ITBio IT

Quality

Operations & ManufacturingOperations & Manufacturing

Business DevelopmentBusiness Development

Corporate CommunicationsCorporate Communications

Product Support

SalesSales

MarketingMarketing

Medical Affairs

Regulatory Affairs

Clinical Development

Project ManagementProject Management

Bio/Pharmaceutical Product Development

Preclinical Research

R&DServices

Operations

Commercial Operations

Page 11: Career Opportunities in the Life Sciences€¦ · Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved. 18 Many Areas to Consider Table

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If you want a 9-5 jobDiscovery ResearchRecruiting

LawLawVenture Capital & Banking

Management Consulting

Bio IT

QualityQuality

Operations & ManufacturingOperations & Manufacturing

Business Development

Corporate Communications

Product SupportProduct Support

Sales

Marketing

Medical Affairs

Regulatory Affairs

Clinical DevelopmentClinical Development

Project Management

Bio/Pharmaceutical Product Development

Preclinical Research

R&DServices

Operations

Commercial Operations

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Who wants to be a CEO one day?Discovery ResearchDiscovery ResearchRecruiting

LawLawVenture Capital & Banking

Venture Capital & Banking

Management ConsultingManagement Consulting

Bio IT

Quality

Business DevelopmentBusiness Development

Corporate Communications

Product Support

SalesSales

MarketingMarketing

Medical Affairs

Regulatory Affairs

Clinical DevelopmentClinical Development

Project ManagementProject Management

Bio/Pharmaceutical Product Development

Preclinical Research

R&DServices

Operations

Commercial Operations

Operations &

Manufacturing

Operations &

Manufacturing

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$$$ CareersDiscovery ResearchRecruiting

LawLawVenture Capital & Banking

Venture Capital & Banking

Management ConsultingManagement Consulting

Bio IT

Quality

Operations & Manufacturing

Business DevelopmentBusiness Development

Corporate Communications

Product Support

SalesSales

MarketingMarketing

Medical AffairsMedical Affairs

Regulatory Affairs

Clinical DevelopmentClinical Development

Project Management

Bio/Pharmaceutical Product Development

Preclinical Research

R&DServices

Operations

Commercial Operations

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If you love writing...Discovery ResearchRecruiting

LawLawVenture Capital & Banking

Management Consulting

Bio IT

Quality

Operations & Manufacturing

Business Development

Corporate CommunicationsCorporate Communications

Product Support

Sales

MarketingMarketing

Medical Affairs

Regulatory AffairsRegulatory Affairs

Clinical DevelopmentClinical Development

Project Management

Bio/Pharmaceutical Product Development

Preclinical Research

R&DServices

Operations

Commercial Operations

Page 15: Career Opportunities in the Life Sciences€¦ · Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved. 18 Many Areas to Consider Table

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The Hidden JobsDiscovery ResearchRecruiting

LawVenture Capital & Banking

Management Consulting

Bio ITBio IT

QualityQuality

Operations & ManufacturingOperations & Manufacturing

Business Development

Corporate Communications

Product SupportProduct Support

Sales

Marketing

Medical AffairsMedical Affairs

Regulatory AffairsRegulatory Affairs

Clinical DevelopmentClinical Development

Project ManagementProject Management

Bio/Pharmaceutical Product Development

Bio/Pharmaceutical Product Development

Preclinical ResearchPreclinical Research

R&DServices

Operations

Commercial Operations

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Hot JobsDiscovery ResearchRecruiting

LawVenture Capital & Banking

Management Consulting

Bio IT

Quality

Operations & ManufacturingOperations & Manufacturing

Business Development

Corporate Communications

Product Support

Sales

Marketing

Regulatory AffairsRegulatory Affairs

Clinical DevelopmentClinical Development

Project ManagementProject Management

Bio/Pharmaceutical Product Development

Bio/Pharmaceutical Product Development

Preclinical ResearchPreclinical Research

R&DServices

Operations

Commercial Operations

Medical

Affairs

Medical

Affairs

Page 17: Career Opportunities in the Life Sciences€¦ · Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved. 18 Many Areas to Consider Table

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So Many Careers To Choose!Discovery ResearchRecruiting

LawVenture Capital & Banking

Management Consulting

Bio IT

Quality

Operations & Manufacturing

Business Development

Corporate Communications

Product Support

Sales

Marketing

Medical Affairs

Regulatory Affairs

Clinical Development

Project Management

Bio/Pharmaceutical Product Development

Preclinical Research

R&DServices

Operations

Commercial Operations

Page 18: Career Opportunities in the Life Sciences€¦ · Copyright © 2007 Career Opportunities in Biotechnology and Drug Development. All rights reserved. 18 Many Areas to Consider Table

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Many Areas to Consider

Table 6-1: Biotechnology and Drug Development Overview... Where the Jobs Are

Drug Discovery & Development

Biotechnology “Tools”

Biotechnology Services

Other Pharma/ Biotech Areas

Government Institutions

Medical Devices Academia

Pharmaceutical companies

Biotechnologytherapeuticcompanies

Vaccines

Drug delivery

MolecularDiagnostics

Reagents and Chemical suppliers

Instruments (e.g., microscopes)

Platform companies (e.g., genomics, proteomics, nanotechnology)

Bio-IT

Software and hardware

Molecular diagnostics

Management consulting and accounting firms

Law firms

Venture capital and investment banking

Recruiting firms

Contract research organizations (CROs)

Contract manufacturers (CMOs)

Research and clinical testing: clinical labs, customized antibodies

Bio-IT

Other agencies and niche providers: PR, advertising, market research, medical communications

Consultants

Agricultural

Industrial biotechnology

Molecular diagnostics

Veterinary companies

Foundations, non-profits, social philanthropy

Clean tech/energy

Nanotech

Journalism

Food and Drug Administration (FDA) and CBER

Centers for Disease Control (CDC)

National Institutes of Health (NIH)

US Patent and Trademark Office (USPTO)

Research institutes and government labs

Homeland security & defense

CIA, FBI, and NASA

Trade commissions

Medical devices

Diagnostic companies

eHealth

Technology transfer

Industry-supported labs and institutes

Education

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Product Development Overview

Chemical and Biological Development, Operations and Manufacturing, Quality

Discovery Research

Lead Optimization of Drug Candidates

Preclinical Studies

Bio/Chemical Process Development

IND filing

Clinical Trials

Scale-Up / Manufacturing

NDA or BLA filing

FDA review

Product Launch!

Commercial Operations and Sales

Phase IIIB/IV Trials

Discovery Research

Preclinical Studies

Clinical Development and Regulatory Affairs

Medical Affairs

Commercial Operations: Marketing, Sales, and Technical Support

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Drug Development: A Risky Endeavor

Millions of compounds

Discovery Research

Lead Optimization of Drug Candidates

Preclinical Studies

Bio/Chemical Process Development

IND filing

Clinical Trials

Scale-Up / Manufacturing

NDA or BLA filing

FDA review

Product Launch!

Commercial Operations and Sales

Phase IIIB/IV Trials

Discovery Research Preclinical Studies Clinical Development and Regulatory Affairs

6-7 1-2 1 in 6

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Career Ladder in Discovery Research

Postdoc

Scientist I - III

Group Leader

Fellow or Principal Scientist

Track

Director

VP Research or CSO

VP R&D

CEO

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Why Work in Industry???

• Most common answer to why people enjoyed their jobs?

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Why Work in Industry???

• Overwhelming feeling of higher aspirations for developing drugs that promise to benefit mankind

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Additional Pros to Working in Industry

• Applied results• Team orientation • Numerous career choices to consider• Job variety• Intensive and continued learning• Unlimited resources to do “big science”

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Negative Aspects to Working in Industry

• Job security• Travel• Stress and deadline pressure• No time to get to the bottom of interesting

biological questions• Project failures and terminations are

frequent and disappointing• Decision making

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Things you can do to Increase Job Security...

• Learn new skills• Stay at the cutting edge• Become a recognized expert in a niche

area• Work in large companies with robust

pipelines• Work in biotechnology hubs• Stay flexible in career

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Themes to Excel

Personality attributes to be successful, regardless of the career?

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Personality Attributes to be Successful in Industry

• Flexibility• Communication skills• Team player attitude• Interpersonal skills• Can-do positive attitude, sense of humor • Ability to multitask• Being able to see the “forest through the trees”• Ability to understand customer’s point of view• Creative problem solving skills

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Academia is Attractive Also!

• An important role in society• Tenure• Pension plans• Freedom for decision making• Ability to remain an expert/retain narrow

focus

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What You Can do Now to Help Eventually Land a Job...

• Work on projects related to human disease rather than esoteric science

• Do drug screens, applied science• Form collaborations with industry• Gain experience with or learn about clinical

trials• Publish, publish, publish (but don’t perish)• Give presentations and attend conferences

and become a perceived expert (get visibility)• Postdoc in industry

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Follow the Industry News

• BioSpace– www.biospace.com

• FierceBiotech– www.fiercebiotech.com

• FierceBioResearch– www.fiercebioresearcher.com

• Nature Biotechnology and Nature Reviews Drug Discovery– www.nature.com/nbt/

• The Scientist-www.the-scientist.com

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Job Search

• Build your network

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Career Planning

Try to go from big to small

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Career Planning

Embrace the concept of “Continued Life-Long Learning”

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Career Advice...

Try to pick your boss, not the company

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Career Advice...

Make sure you fit into the culture

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More Career Advice...

Interview the company as much as they interview you

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More Interviewing Advice...

• Don’t interview like a postdoc!

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Career Planning

Find your niche

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Bay Area Employment Economics

• Recent and some spectacular layoffs in the Bay Area in both biotech and medical device companies:

Amgen, Roche, Scios, Alza, Renovis, Corgentech, Sunesis, Telik, Ilypsa, Affymetrix, Threshold, Nektar, PDL, more

Boston Scientific, Abbott, Medtronic, more

• Large lay-offs in pharma also• Large pool of qualified talent is available—highly

competitive

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VCs are Funding Biotech and Medical Device Companies

Source: PriceWaterhouseCoopers, Money Tree

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The Future of Biotech is Promising

• Significant unmet medical needs remain—neurological disorders, cancer, infectious diseases, diabetes, obesity, cardiovascular diseases

• Energy• Aging population• Tremendous market opportunity in China

and India

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Thank you!

Wishing you much success in your endeavors!May you find a cure for cancer!

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Speaking Engagements

• Teri Hankes’s ‘Alternative Careers in Medicine Series’, April 17th, Stanford, from 5-6 pm

• Free sample chapter on Careers in Project Management available on my website at www.careersbiotech.com

• Books available at campus career centers

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Contact Information

Toby Freedman, Ph.D.President, Synapsis [email protected]

Website for book: www.careersbiotech.com

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Acknowledgments

• Over 200+ industry professionals

Special Thanks to:• Molly Schmid, Joseph Carlino, Betsy Alberty,

Angelie Agarwal, Bill Lindstaedt

Even More Special Thanks to:• My father, Bill Freedman, who edited the

chapters multiple times and Peter Symonds

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If only books grew on trees!