Klinefelter’s Syndrome

By: GP

Medical AnswersQ: How does a person inherit Klinefelter’s Syndrome? Is it dominant recessive, sex-linked, too many/ too few chromosomes, or a mutation? A: Klinefelter’s Syndrome is a disorder that only affects males. This rarely occurs, but when it does, it happens when a parent gives an extra “x” chromosome.

Q: What are the possible genotypes of the parents? If the disease is a chromosomal abnormality, describe the abnormality.A: One parent, the female, give two x chromosomes, while the male gives an x and a y chromosome. However during Klinefelter’s syndrome, the offspring obtains an extra x chromosome.

Q: How prevalent is the disease in the population? What are the chances of a person with this disease passing the disease to their offspring ?A: The chances of getting this disorder, is very rare. The chances are between 1 in 500 and 1 in 1000

Q: How is the disease diagnosed?A: The disease is usually diagnosed during the female’s pregnancy, or during the males puberty session

“XXY”

Medical Answers continued…Q: What are physical symptoms of the disease?A: Extra breast, little facial and body, less muscular body, and infertilely

Q: What is the life expectancy of someone with the disease?A: A male with this disease could live as long as a regular person, just with some obstacles during life.

Q: How can this disease be treated?A: A way this disease could be treated, is to take hormone replacement therapy, synthetic testerone.

Personal AnswersQ: What is everyday life like?A: A person having to deal with this disorder, is sometimes very difficult. Since they don’t have a very muscular body, they have to exercise more often, they also have to go to therapy.

Q: What limitations does the person have?A: The person with the disease is not able to produce a sperm, they are least likely to have a child.

Q: What are some organizations that can help a family cope with a child’s disorder?A: There are many organizations to help a family cope with the child’s disorder, like Medscape.com, it shows Klinefelter’s Syndrome treatment and management. Another website is nichd.nih.gov .

Q: How possible is it that cure will be found?A: I believe that a cure will not be found, but some centers provide therapy for people with this disease.

Other Interesting Information

Q: What made you choose this particular disease?A: I chose this disease, because I had no idea what this disease was, but now that I know what it is, if I meet someone with Klinefelter’s syndrome, I could try to help and interact with them.

Q: Include something else about this disorder that interests you.A: This disease, Klinefelter’s Syndrome, was named after Dr. Harry Klinefelter, he was the first diagnosed with the disease.

Work Cited

Bojesen, A., Juul S., & Gravholt, C.H. (2003). Prenatal and postnatal prevalence of Klinefelter syndrome: A national registry study. Journal of Clinical Endocrinology & Metabolism, 88(2), 622-626. 

Milunsky, Aubrey. "Klinefelter's Syndrome." Encyclopedia Americana. Grolier Online, 2014. Web. 26 Feb. 2014.

"Klinefelter Syndrome." Grolier Multimedia Encyclopedia. Grolier Online, 2014. Web. 27 Feb. 2014.

"Klinefelter Syndrome." Klinefelter Syndrome. N.p., n.d. Web. 26 Feb. 2014. <http://learn.genetics.utah.edu/content/disorders/chromosomal/klinefelter/>